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Overview

ID MAG01682
Name HFD3_bin.22
Sample SMP0045
Taxonomy
Kingdom Bacteria
Phylum Gemmatimonadota
Class Gemmatimonadetes
Order Gemmatimonadales
Family Gemmatimonadaceae
Genus UBA4720
Species
Assembly information
Completeness (%) 53.27
Contamination (%) 0.33
GC content (%) 60.0
N50 (bp) 4,048
Genome size (bp) 2,104,309

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2163

Gene name Description KEGG GOs EC E-value Score Sequence
HFD3_k127_1012149_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.781e-197 624.0
HFD3_k127_1012149_1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00263 - 1.4.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 508.0
HFD3_k127_1012149_2 - - - - 0.0000000000000000000000000000000000000000000000000002446 188.0
HFD3_k127_1012149_3 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000005582 63.0
HFD3_k127_1016283_0 Carboxypeptidase regulatory-like domain - - - 2.265e-295 921.0
HFD3_k127_1039620_0 coagulation factor 5 8 type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 527.0
HFD3_k127_1039620_1 COG2723 Beta-glucosidase 6-phospho-beta-glucosidase beta- galactosidase K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 374.0
HFD3_k127_1057233_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 301.0
HFD3_k127_1057233_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000001158 237.0
HFD3_k127_1057233_2 NUDIX domain K08310 - 3.6.1.67 0.00000000000001024 74.0
HFD3_k127_1063285_0 Cytochrome C biogenesis protein transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000178 205.0
HFD3_k127_1063285_1 Disulphide bond corrector protein DsbC K04084 - 1.8.1.8 0.00000000000000001555 92.0
HFD3_k127_1070307_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 509.0
HFD3_k127_1070307_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004694 483.0
HFD3_k127_1070307_2 MoaE protein K03635 - 2.8.1.12 0.00000000000000000000000000000000003568 139.0
HFD3_k127_1070307_3 molybdopterin converting factor K03635,K21142 - 2.8.1.12 0.0000000008987 62.0
HFD3_k127_1082569_0 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 407.0
HFD3_k127_1082569_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003741 330.0
HFD3_k127_1082569_2 MotA/TolQ/ExbB proton channel family K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001944 283.0
HFD3_k127_1082569_3 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.00000000000000000000000000000000000000000000000001552 183.0
HFD3_k127_1082569_4 TIGRFAM siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.00000000000003924 84.0
HFD3_k127_1082569_5 PFAM cytochrome c assembly protein - - - 0.0000000002703 70.0
HFD3_k127_1085536_0 Tricorn protease homolog - - - 3.86e-225 718.0
HFD3_k127_1085536_1 Glycosyl hydrolase family 20, domain 2 K12373 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 470.0
HFD3_k127_109486_0 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000451 435.0
HFD3_k127_109486_1 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006199 334.0
HFD3_k127_109486_2 M42 glutamyl aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 319.0
HFD3_k127_109486_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000007375 215.0
HFD3_k127_109486_4 - - - - 0.00000000000000000000000000000001255 131.0
HFD3_k127_1108022_0 Amidohydrolase family - - - 6.316e-230 722.0
HFD3_k127_1108022_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009468 488.0
HFD3_k127_1108022_2 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000000000000000000000000000000000000000000000000000001306 210.0
HFD3_k127_1108807_0 Domain of unknown function (DUF3471) K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 480.0
HFD3_k127_1108807_1 Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 0.000000000000000006712 93.0
HFD3_k127_1124647_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0 1208.0
HFD3_k127_1124647_1 Surface antigen K07277,K07278 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 374.0
HFD3_k127_1135171_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 7.132e-232 725.0
HFD3_k127_1135171_1 Carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000001219 197.0
HFD3_k127_1135171_2 Elongation factor SelB winged helix K03833 - - 0.0000000000000002449 86.0
HFD3_k127_1139105_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 - 6.1.1.14 1.769e-217 680.0
HFD3_k127_1139105_1 metalloendopeptidase activity K08602 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007293 541.0
HFD3_k127_1139105_2 Peptidase family M20/M25/M40 K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003564 283.0
HFD3_k127_1147038_0 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 442.0
HFD3_k127_1147038_1 Glycosyl transferases group 1 K13668 - 2.4.1.346 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 361.0
HFD3_k127_1147038_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 302.0
HFD3_k127_1147038_3 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003961 295.0
HFD3_k127_1158191_0 Tetratricopeptide repeat K08884,K12132 - 2.7.11.1 1.581e-239 759.0
HFD3_k127_1158191_1 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000003246 205.0
HFD3_k127_1166637_0 Bacterial extracellular solute-binding protein K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009535 389.0
HFD3_k127_1166637_1 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 317.0
HFD3_k127_1166637_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 306.0
HFD3_k127_1166637_3 TIGRFAM phosphate ABC transporter K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000802 302.0
HFD3_k127_1166637_4 ATPases associated with a variety of cellular activities K02036 - 3.6.3.27 0.000000000000000000000000005858 113.0
HFD3_k127_1190275_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 425.0
HFD3_k127_1190275_1 Protein of unknown function (DUF541) K09797 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003262 276.0
HFD3_k127_1190275_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000002809 145.0
HFD3_k127_1195582_0 Protein kinase domain K12132 - 2.7.11.1 1.042e-262 818.0
HFD3_k127_1195582_1 Transcriptional regulator K21701 - - 0.000000000000000001209 90.0
HFD3_k127_1201281_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain K15778 - 5.4.2.2,5.4.2.8 1.543e-204 644.0
HFD3_k127_1201281_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 494.0
HFD3_k127_1201281_2 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000009473 209.0
HFD3_k127_1201281_3 Uncharacterised protein family (UPF0182) K09118 - - 0.0000000000000000000000000000003404 130.0
HFD3_k127_1206261_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004666 291.0
HFD3_k127_1206261_1 CarboxypepD_reg-like domain - - - 0.000000000000000000000000000000000000000000001527 168.0
HFD3_k127_120662_0 lysine 2,3-aminomutase activity K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000008042 264.0
HFD3_k127_120662_1 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000005079 119.0
HFD3_k127_1215645_0 Cytidylate kinase K00876 - 2.7.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 305.0
HFD3_k127_1215645_1 - - - - 0.00000000000000000000008724 104.0
HFD3_k127_1215645_2 Transcription factor zinc-finger K09981 - - 0.0000000000000000000009853 101.0
HFD3_k127_1215645_3 transferase activity, transferring glycosyl groups - - - 0.0000000006758 68.0
HFD3_k127_1215645_4 - - - - 0.00001096 50.0
HFD3_k127_122030_0 TIGRFAM NiFe hydrogenase maturation protein HypF K04656 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000702 636.0
HFD3_k127_122030_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 359.0
HFD3_k127_122030_2 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000896 228.0
HFD3_k127_122030_3 Prokaryotic cytochrome b561 K03620 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000002299 166.0
HFD3_k127_122030_4 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.000000000000000000000000000001239 127.0
HFD3_k127_1225999_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 2.263e-211 664.0
HFD3_k127_1225999_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007993 477.0
HFD3_k127_1225999_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009941,GO:0031967,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0048046 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 328.0
HFD3_k127_1225999_3 Protein of unknown function (DUF520) K09767 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001291 247.0
HFD3_k127_1237142_0 beta-N-acetylglucosaminidase K01197 - 3.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 467.0
HFD3_k127_1237142_1 Phosphoesterase family K01114 - 3.1.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 407.0
HFD3_k127_1237142_2 Belongs to the MtfA family K09933 - - 0.000000000000000000000000000000000000000000000000000000000000000001258 237.0
HFD3_k127_1237142_3 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000009915 193.0
HFD3_k127_1237142_4 NmrA-like family - - - 0.0000000000000000000000000000000000000000000001731 179.0
HFD3_k127_1237142_5 Protein of unknown function (DUF1697) - - - 0.00000000000000001817 90.0
HFD3_k127_1252597_0 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 429.0
HFD3_k127_1252597_1 polysaccharide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 324.0
HFD3_k127_1252597_2 NAD(P)H-binding K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000001196 205.0
HFD3_k127_1252597_3 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000007464 165.0
HFD3_k127_1253454_0 SAF domain K01654,K15898,K18430 - 2.5.1.101,2.5.1.56,2.5.1.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 382.0
HFD3_k127_1253454_1 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000001141 171.0
HFD3_k127_1253454_2 ABC-type polysaccharide polyol phosphate transport system, ATPase component K09691 - - 0.00000000001349 73.0
HFD3_k127_1253454_3 Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase K07257 - - 0.00000343 53.0
HFD3_k127_126279_0 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000006305 241.0
HFD3_k127_126279_1 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000004638 220.0
HFD3_k127_1263607_0 Thymidine kinase K00857 - 2.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 314.0
HFD3_k127_1263607_1 DbpA RNA binding domain K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000001076 253.0
HFD3_k127_1263607_2 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000000000000004567 240.0
HFD3_k127_1263607_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000001996 175.0
HFD3_k127_1276790_0 TonB-linked outer membrane protein, SusC RagA family - - - 0.0 1308.0
HFD3_k127_1276790_1 Starch-binding associating with outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 429.0
HFD3_k127_1279455_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0 1389.0
HFD3_k127_1279455_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008189 434.0
HFD3_k127_1279455_2 Biotin/lipoate A/B protein ligase family K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000000000000000000000000000002589 237.0
HFD3_k127_1279455_3 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000007109 57.0
HFD3_k127_1306729_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 612.0
HFD3_k127_1306729_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003765 253.0
HFD3_k127_1306729_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000008674 207.0
HFD3_k127_1306729_3 Major intrinsic protein K06188 - - 0.00000000000000000000000000000000000001149 148.0
HFD3_k127_1315046_0 GMC oxidoreductase K03333 - 1.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 355.0
HFD3_k127_1315046_1 Cytochrome C oxidase, cbb3-type, subunit III K19713 - 1.8.2.2 0.00000000000000000000000000002186 123.0
HFD3_k127_1329226_0 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) K00164 GO:0003674,GO:0003824,GO:0004591,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016624,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494,GO:1990204,GO:1990234 1.2.4.2 1.842e-243 781.0
HFD3_k127_1329226_1 GlcNAc-PI de-N-acetylase - - - 1.108e-223 722.0
HFD3_k127_1329226_2 iron ion homeostasis K02012 - - 0.000000000000000000000000000000018 129.0
HFD3_k127_133849_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 5.044e-321 990.0
HFD3_k127_133849_1 Serine dehydratase beta chain K01752 - 4.3.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 362.0
HFD3_k127_133849_2 Serine dehydratase alpha chain K01752 - 4.3.1.17 0.000000000000000000000000002431 113.0
HFD3_k127_1348829_0 Capsule assembly protein Wzi - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005715 317.0
HFD3_k127_1348829_1 undecaprenyl-phosphate glucose phosphotransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008926 277.0
HFD3_k127_1348829_2 Capsule assembly protein Wzi - - - 0.00000000000000000000000000000000000000000000000149 186.0
HFD3_k127_1366252_0 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 394.0
HFD3_k127_1366252_1 Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008135 340.0
HFD3_k127_1366252_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006175 324.0
HFD3_k127_1377015_0 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000007557 231.0
HFD3_k127_1377015_1 - - - - 0.000000000000000000000000000001312 128.0
HFD3_k127_1377015_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000001681 115.0
HFD3_k127_1381806_0 pyrroloquinoline quinone binding - - - 2.566e-200 631.0
HFD3_k127_1381806_1 Belongs to the HpcH HpaI aldolase family K18292 - 4.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000802 500.0
HFD3_k127_1381806_2 Urate oxidase N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 497.0
HFD3_k127_1381806_3 tRNA wobble adenosine to inosine editing - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002355 255.0
HFD3_k127_1381806_4 allantoin biosynthetic process K01477,K16840 - 3.5.3.4,4.1.1.97 0.0000000000000000000000000000000000000000000002477 171.0
HFD3_k127_1381806_5 DNA-binding transcription factor activity - - - 0.00000000000000000000000000000000000000002131 157.0
HFD3_k127_1381806_6 hydroxyisourate hydrolase activity K07127,K13485 GO:0006139,GO:0006144,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009112,GO:0009987,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:1901360,GO:1901564 3.5.2.17,4.1.1.97 0.0000000000000000000000000000000226 130.0
HFD3_k127_1381806_7 PFAM OsmC family protein - - - 0.00000000000000000000008855 103.0
HFD3_k127_1381806_8 methylamine metabolic process K15977 - - 0.000000007125 58.0
HFD3_k127_1387864_0 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 318.0
HFD3_k127_1387864_1 Glutathione peroxidase - - - 0.0000000000000000000000000000000000000000000000004736 181.0
HFD3_k127_1387864_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000085 171.0
HFD3_k127_1387864_3 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.000000000000000000000002127 112.0
HFD3_k127_1387864_4 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000001141 89.0
HFD3_k127_139704_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 9.935e-228 715.0
HFD3_k127_139704_1 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 299.0
HFD3_k127_139704_2 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000008512 207.0
HFD3_k127_139704_3 Major facilitator Superfamily - - - 0.000000000000000000000000000000000003457 145.0
HFD3_k127_1408134_0 CcmB protein K02194 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 300.0
HFD3_k127_1408134_1 Cytochrome C assembly protein K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000003617 233.0
HFD3_k127_1408134_2 ABC transporter K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000000000003935 217.0
HFD3_k127_1408134_3 sequence-specific DNA binding - - - 0.000000000000000000000000000000000000000000001733 169.0
HFD3_k127_1409279_0 Saccharopine dehydrogenase C-terminal domain K19064 - 1.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 573.0
HFD3_k127_1409279_1 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008874 537.0
HFD3_k127_1409279_2 CoA binding domain K06929 - - 0.00000000000000000000000000000000000000000000000000000009087 199.0
HFD3_k127_1409279_3 - - - - 0.00000000000000000000000000000000009238 139.0
HFD3_k127_1409279_4 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.0000003716 51.0
HFD3_k127_1419398_0 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006938 258.0
HFD3_k127_1419398_1 Zinc carboxypeptidase K14054 - - 0.000000000000000000000000000002044 124.0
HFD3_k127_1438700_0 Domain of unknown function (DUF5117) - - - 2.486e-258 814.0
HFD3_k127_1438700_1 Putative peptidoglycan binding domain K21470 - - 0.00000000002873 65.0
HFD3_k127_1444210_0 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002523 339.0
HFD3_k127_1444210_1 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000000000000003092 195.0
HFD3_k127_1444210_2 Glycosyl transferase family 2 - - - 0.0000000000000000000000001088 108.0
HFD3_k127_1453401_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 2.157e-287 892.0
HFD3_k127_1453401_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004257 523.0
HFD3_k127_1453401_2 Aromatic amino acid lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000001035 245.0
HFD3_k127_1453401_3 Amidohydrolase family K01468 - 3.5.2.7 0.000006245 49.0
HFD3_k127_1458138_0 heme-copper terminal oxidase activity K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 617.0
HFD3_k127_1458138_1 cytochrome c oxidase (Subunit II) - - - 0.000000000000000000000000000000000000000000000000000000139 204.0
HFD3_k127_1458138_2 Transcriptional regulator - - - 0.000000000000000000000000003207 116.0
HFD3_k127_1458138_3 - - - - 0.0002445 46.0
HFD3_k127_1470625_0 Peptidase S46 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 552.0
HFD3_k127_1470625_1 Uncharacterized protein family (UPF0051) K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 439.0
HFD3_k127_1470625_2 SIS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008178 387.0
HFD3_k127_1470625_3 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 327.0
HFD3_k127_1470625_4 Psort location CytoplasmicMembrane, score 10.00 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001581 283.0
HFD3_k127_1470625_5 SnoaL-like domain - - - 0.00000000000000000000000000000000000004395 148.0
HFD3_k127_1470625_6 the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE K09013 - - 0.000000000000000000001879 93.0
HFD3_k127_1470625_7 - - - - 0.000000000000000001319 87.0
HFD3_k127_1470625_8 PFAM Forkhead-associated protein - - - 0.00000000002055 71.0
HFD3_k127_1508317_0 Flavin containing amine oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 4.308e-210 664.0
HFD3_k127_1508317_1 Carotenoid biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002196 277.0
HFD3_k127_1508317_2 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000005075 267.0
HFD3_k127_1508317_4 Acyl-transferase K00655 - 2.3.1.51 0.00006543 49.0
HFD3_k127_151248_0 Peptidase C26 K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000003215 220.0
HFD3_k127_1519267_0 Metallopeptidase family M24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007761 530.0
HFD3_k127_1519267_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 375.0
HFD3_k127_1519267_2 - - - - 0.000000000000000000000000000000000000000000000000000000000001674 222.0
HFD3_k127_1519267_3 Integral membrane protein DUF92 - - - 0.000000000000000000000000000000000000000000000000000000000007419 217.0
HFD3_k127_1519267_4 B12 binding domain K04034 - 1.21.98.3 0.00000000000000004692 85.0
HFD3_k127_1519267_5 Glycosyl hydrolases family 18 - - - 0.0002546 52.0
HFD3_k127_1520069_0 Putative glucoamylase - - - 1.362e-197 626.0
HFD3_k127_1520069_1 coagulation factor 5 8 type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 554.0
HFD3_k127_1520069_2 ABC transporter substrate-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003653 449.0
HFD3_k127_1520069_3 transmembrane transport K02025,K15771 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005092 399.0
HFD3_k127_1520069_4 ABC-type sugar transport system, permease component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 343.0
HFD3_k127_1520069_5 TonB-dependent receptor - - - 0.0000000000000000000000000000000000001779 149.0
HFD3_k127_152046_0 Transporter associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 589.0
HFD3_k127_152046_1 Two component, sigma54 specific, transcriptional regulator, Fis family K02667,K07713,K07714,K19641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 445.0
HFD3_k127_152046_2 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 301.0
HFD3_k127_152046_3 PAS domain K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000006776 279.0
HFD3_k127_152046_4 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000001043 145.0
HFD3_k127_152046_5 Prokaryotic N-terminal methylation motif K02456,K02650,K02655 - - 0.00000000000000009043 86.0
HFD3_k127_1541283_0 RecQ zinc-binding K03654 - 3.6.4.12 2.087e-194 615.0
HFD3_k127_1541283_1 Glycosyltransferase family 9 (heptosyltransferase) K02841,K02843,K02849,K12982 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.00000000000000000000000001936 110.0
HFD3_k127_1542386_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 597.0
HFD3_k127_1542386_1 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000000000000000000001056 243.0
HFD3_k127_1542386_2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000007442 171.0
HFD3_k127_157305_0 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 9.228e-235 740.0
HFD3_k127_157305_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 500.0
HFD3_k127_157305_2 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 438.0
HFD3_k127_157305_3 HD superfamily hydrolase involved in NAD metabolism K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000002021 214.0
HFD3_k127_1574423_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.97e-271 841.0
HFD3_k127_1574423_1 Protein of unknown function (DUF1232) - - - 0.0000000000000000000000000000000000000006547 153.0
HFD3_k127_1574423_2 - - - - 0.0000000000000000000007388 100.0
HFD3_k127_1593526_0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 558.0
HFD3_k127_1593526_1 Transketolase, pyrimidine binding domain K00167,K11381,K21417 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 293.0
HFD3_k127_1593526_2 PFAM Glycosyl transferases group 1 - - - 0.000000000001654 71.0
HFD3_k127_1596202_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007916 507.0
HFD3_k127_1608748_0 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000001323 224.0
HFD3_k127_1608748_1 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.0000001658 55.0
HFD3_k127_1615811_0 Multicopper oxidase K22348 - 1.16.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008183 529.0
HFD3_k127_1615811_1 Multicopper oxidase K00368 - 1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 410.0
HFD3_k127_1615811_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 305.0
HFD3_k127_1615811_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 296.0
HFD3_k127_1615811_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07675 - 2.7.13.3 0.000000000000000000000003309 115.0
HFD3_k127_1633045_0 Threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 323.0
HFD3_k127_1633045_1 peroxiredoxin activity K03564 - 1.11.1.15 0.00000000000000000000000007794 115.0
HFD3_k127_1649612_0 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000002815 149.0
HFD3_k127_1649612_1 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000003163 147.0
HFD3_k127_1649612_2 Glycosyltransferase like family 2 - - - 0.000000000000000003036 96.0
HFD3_k127_1649612_3 nodulation K00612 - - 0.0000000000000003893 84.0
HFD3_k127_1649612_4 Nodulation protein S (NodS) - - - 0.000000000000003707 84.0
HFD3_k127_1664421_0 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 411.0
HFD3_k127_1664421_1 flavoprotein involved in K transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009332 259.0
HFD3_k127_1664421_2 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K00950,K01633 GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042221,GO:0042364,GO:0042398,GO:0042493,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.13.11.81,2.5.1.15,2.7.6.3,4.1.2.25,5.1.99.8 0.00000000000000000000000000002048 122.0
HFD3_k127_1714530_0 Insulinase (Peptidase family M16) K07263 - - 5.812e-268 856.0
HFD3_k127_174693_0 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 340.0
HFD3_k127_174693_1 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009104 259.0
HFD3_k127_174693_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000000000000000001299 226.0
HFD3_k127_174693_3 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000000000000002218 218.0
HFD3_k127_174693_4 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000001979 195.0
HFD3_k127_174693_5 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000000000000000002177 165.0
HFD3_k127_174693_6 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000000000000116 134.0
HFD3_k127_174693_7 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000001742 100.0
HFD3_k127_174693_8 Ribosomal L29 protein K02904 - - 0.00000000000001024 78.0
HFD3_k127_1787729_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000002439 164.0
HFD3_k127_1787729_1 BON domain - - - 0.000000000000000000000000000000000002121 142.0
HFD3_k127_1787729_2 Transglycosylase associated protein - - - 0.0000000000000000000000000000001498 128.0
HFD3_k127_1788538_0 DEAD DEAH box K03724 - - 7.913e-208 687.0
HFD3_k127_1788538_1 Protein of unknown function (DUF1624) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005962 379.0
HFD3_k127_1788538_2 MerR HTH family regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004282 256.0
HFD3_k127_1788538_3 hydrolase activity, acting on ester bonds K01563 - 3.8.1.5 0.00000000000000000000000000000000000000000000000000009142 197.0
HFD3_k127_1793646_0 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 310.0
HFD3_k127_1793646_1 tail specific protease K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003188 273.0
HFD3_k127_1793646_2 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000000000000000000000000000000005297 157.0
HFD3_k127_1793646_3 Domain of unknown function (DUF2520) - - - 0.00000000000000000000000000000009569 135.0
HFD3_k127_1796678_0 MatE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 509.0
HFD3_k127_1796678_1 DegT DnrJ EryC1 StrS aminotransferase family K02805 - 2.6.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000006062 259.0
HFD3_k127_1796678_2 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000001789 224.0
HFD3_k127_1813525_0 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 294.0
HFD3_k127_1813525_1 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000001317 169.0
HFD3_k127_1813525_2 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000006185 147.0
HFD3_k127_1813525_3 O-antigen polysaccharide polymerase Wzy - - - 0.00000000000000000000000000000997 134.0
HFD3_k127_1813525_4 transferase activity, transferring glycosyl groups K00786 - - 0.00000000000000000000001106 102.0
HFD3_k127_1813525_5 Glycosyl transferase family group 2 - - - 0.000000000000000003242 96.0
HFD3_k127_1813525_6 Glycosyltransferase like family 2 - - - 0.000000000007534 77.0
HFD3_k127_1836926_0 Peptidase dimerisation domain K13049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005831 488.0
HFD3_k127_1836926_1 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 317.0
HFD3_k127_1836926_2 DinB family - - - 0.0000001737 61.0
HFD3_k127_1842006_0 Tetratricopeptide repeat - - - 1.284e-207 660.0
HFD3_k127_1842006_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 305.0
HFD3_k127_1842006_2 Bacterial Ig-like domain 2 - - - 0.0000001262 64.0
HFD3_k127_1846177_0 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 549.0
HFD3_k127_1846177_1 Domain of unknown function (DUF4112) - - - 0.000000000000000000000000000000000000001883 152.0
HFD3_k127_1846177_2 - - - - 0.000000000000001573 77.0
HFD3_k127_1846177_3 Domain of unknown function (DUF4412) - - - 0.0000001081 63.0
HFD3_k127_1846177_4 - - - - 0.0002447 49.0
HFD3_k127_1862_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007105 568.0
HFD3_k127_1862_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000003945 147.0
HFD3_k127_1878645_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 571.0
HFD3_k127_1878645_1 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000000000000000005198 211.0
HFD3_k127_1878645_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0001742 47.0
HFD3_k127_1880778_0 Dipeptidyl carboxypeptidase K01284 - 3.4.15.5 3.323e-249 782.0
HFD3_k127_1880778_1 transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 532.0
HFD3_k127_1904417_0 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 445.0
HFD3_k127_1921475_0 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 515.0
HFD3_k127_1921475_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006614 386.0
HFD3_k127_1921475_2 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 315.0
HFD3_k127_1921475_3 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000001929 113.0
HFD3_k127_1921475_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000001488 87.0
HFD3_k127_1921475_5 TIGRFAM thiamine biosynthesis protein ThiS K03154 - - 0.000000000004755 69.0
HFD3_k127_192250_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 1.228e-231 722.0
HFD3_k127_192250_1 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007743 516.0
HFD3_k127_192250_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007649 442.0
HFD3_k127_192250_3 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 385.0
HFD3_k127_1926407_0 Competence-damaged protein K03742 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 449.0
HFD3_k127_1926407_1 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000000000005013 184.0
HFD3_k127_1926407_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000005345 141.0
HFD3_k127_1959871_0 Aminotransferase class-V - - - 2.021e-194 621.0
HFD3_k127_1959871_1 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004496 375.0
HFD3_k127_1959871_2 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000008597 155.0
HFD3_k127_1959871_3 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000005412 135.0
HFD3_k127_1961116_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K02567 - - 3.42e-282 888.0
HFD3_k127_1961116_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.000000000000001259 90.0
HFD3_k127_1962957_0 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 368.0
HFD3_k127_1962957_1 cheY-homologous receiver domain - - - 0.000000000000000000000000000000262 124.0
HFD3_k127_1963379_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 549.0
HFD3_k127_1963379_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006004 471.0
HFD3_k127_1963379_2 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 463.0
HFD3_k127_1963379_3 BON domain - - - 0.000000000000000000000000000000000000000000000000000000002374 210.0
HFD3_k127_1981675_0 Pyridoxal-dependent decarboxylase conserved domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001942 240.0
HFD3_k127_1981675_1 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000007043 149.0
HFD3_k127_1981675_2 PRC-barrel domain - - - 0.00000000000000009546 91.0
HFD3_k127_1981675_3 Beta-eliminating lyase K01667 - 4.1.99.1 0.000000000000004593 76.0
HFD3_k127_1981675_4 activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation - - - 0.000000000002662 68.0
HFD3_k127_1982648_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 1e-323 1007.0
HFD3_k127_1982648_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 - 5.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009456 430.0
HFD3_k127_1982648_2 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 414.0
HFD3_k127_1982648_3 Protein kinase domain K08884,K12132 - 2.7.11.1 0.000000000000000002226 87.0
HFD3_k127_2013060_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 3.202e-200 659.0
HFD3_k127_2013060_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003684 558.0
HFD3_k127_2013060_2 Surface antigen K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 557.0
HFD3_k127_2025577_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 452.0
HFD3_k127_2025577_1 AcrB/AcrD/AcrF family K07787,K15726 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003253 253.0
HFD3_k127_2027664_0 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000002067 227.0
HFD3_k127_2027664_1 STAS domain K04749 - - 0.000000000000000000000000000000000000000000000000000007825 191.0
HFD3_k127_2027664_2 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.000000000000000000000000000000000000000002744 160.0
HFD3_k127_2027664_3 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000006963 147.0
HFD3_k127_2029642_0 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 333.0
HFD3_k127_2029642_1 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000001356 164.0
HFD3_k127_2032677_0 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005422 329.0
HFD3_k127_2032677_1 thiolester hydrolase activity - - - 0.00000000007654 67.0
HFD3_k127_2037459_0 Sortilin, neurotensin receptor 3, - - - 0.0 1030.0
HFD3_k127_2043204_0 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 374.0
HFD3_k127_2043204_1 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 359.0
HFD3_k127_2043204_2 - - - - 0.0000000000000000000000007482 111.0
HFD3_k127_2043204_3 OsmC-like protein K07397 - - 0.000007112 48.0
HFD3_k127_2045369_0 Heavy metal translocating P-type atpase K01533 - 3.6.3.4 9.338e-196 625.0
HFD3_k127_2045369_1 P-type ATPase K17686 - 3.6.3.54 0.0000000000002516 74.0
HFD3_k127_2048777_0 Succinyl-CoA ligase like flavodoxin domain - - - 5.502e-271 854.0
HFD3_k127_2048777_1 Domain of unknown function (DUF4010) - - - 0.0000000000000000000000000000000000000000000000000000000000002047 223.0
HFD3_k127_2048777_2 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000002109 156.0
HFD3_k127_2048777_3 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.00000000000000000000000000000000003859 139.0
HFD3_k127_2048777_4 Yip1 domain - - - 0.0000000000000000000000000000002438 133.0
HFD3_k127_2048777_5 helix_turn_helix, Lux Regulon - - - 0.000000000000000000002592 100.0
HFD3_k127_2055982_0 Fumarase C C-terminus K01744 - 4.3.1.1 9.757e-228 713.0
HFD3_k127_2055982_1 asparaginase K01424,K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.1,3.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 457.0
HFD3_k127_2055982_2 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000001032 239.0
HFD3_k127_2055982_3 Methyl-accepting chemotaxis protein (MCP) signaling domain K03406 - - 0.000000000000000000001008 109.0
HFD3_k127_2064177_0 Formiminotransferase domain, N-terminal subdomain K13990 - 2.1.2.5,4.3.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008293 407.0
HFD3_k127_2064177_1 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 368.0
HFD3_k127_2064177_2 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000001961 245.0
HFD3_k127_208682_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000003356 223.0
HFD3_k127_208682_1 Protein of unknown function (DUF1343) - - - 0.00000000000000000000000000000000000000000000000000006276 194.0
HFD3_k127_208682_2 - - - - 0.0002311 48.0
HFD3_k127_2095869_0 tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 3.415e-211 663.0
HFD3_k127_2095869_1 protein histidine kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005641 308.0
HFD3_k127_2095869_2 MazG nucleotide pyrophosphohydrolase domain K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000001214 258.0
HFD3_k127_2104514_0 - - - - 0.00000000000000000000000000000000000000000000000000007227 190.0
HFD3_k127_2104514_1 N-acetyltransferase K00675 - 2.3.1.118 0.000000000000000000000000000001226 133.0
HFD3_k127_2104514_2 - - - - 0.00000000000000000007025 90.0
HFD3_k127_2104514_3 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00001215 56.0
HFD3_k127_2115370_0 COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 341.0
HFD3_k127_2115370_1 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000002609 174.0
HFD3_k127_2115370_2 Domain of unknown function (DUF1707) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000004449 53.0
HFD3_k127_2140896_0 Peptidase M15 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005482 296.0
HFD3_k127_2140896_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000001632 163.0
HFD3_k127_2140896_2 Prokaryotic N-terminal methylation motif K02456,K02650,K02655 - - 0.0000000001011 66.0
HFD3_k127_2149421_0 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 346.0
HFD3_k127_2149421_1 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 311.0
HFD3_k127_2149421_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K05606 - 5.1.99.1 0.0000000000000000000000000000000003696 131.0
HFD3_k127_2149421_3 - - - - 0.00000000000000000000000008059 115.0
HFD3_k127_2149421_4 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000002689 82.0
HFD3_k127_2149421_5 - - - - 0.000002213 55.0
HFD3_k127_2159392_0 6-phosphogluconolactonase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 301.0
HFD3_k127_2159392_1 PFAM cytochrome c biogenesis protein transmembrane region - - - 0.00000000000000000000000000000000000000000000000000000000004505 211.0
HFD3_k127_2159392_10 - - - - 0.0000004634 57.0
HFD3_k127_2159392_2 Sigma-70 region 2 - - - 0.000000000000000000000000000000000000000000000000000000001074 208.0
HFD3_k127_2159392_3 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000000000000003367 198.0
HFD3_k127_2159392_4 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000002162 181.0
HFD3_k127_2159392_5 Protein of unknown function, DUF417 - - - 0.0000000000000000000000000000000001862 138.0
HFD3_k127_2159392_6 Bacterial transcriptional activator domain K12132 - 2.7.11.1 0.00000000000000001968 84.0
HFD3_k127_2159392_7 Putative zinc-finger - - - 0.0000000000000001258 84.0
HFD3_k127_2159392_9 flavoprotein K19784 - - 0.00000000008687 68.0
HFD3_k127_217278_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 5.477e-299 935.0
HFD3_k127_217278_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 371.0
HFD3_k127_217278_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000001717 98.0
HFD3_k127_217278_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000266 79.0
HFD3_k127_2174039_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.5e-323 1000.0
HFD3_k127_2174039_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000003394 254.0
HFD3_k127_2174039_2 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000004816 251.0
HFD3_k127_2174039_3 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000000001893 150.0
HFD3_k127_2174666_0 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 444.0
HFD3_k127_2174666_1 Fimbrial assembly protein (PilN) - - - 0.00000000000000000000000000000000000000000000000000007421 195.0
HFD3_k127_2174666_2 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000000000000000000001063 156.0
HFD3_k127_2174666_3 - - - - 0.0000000000000000000000004739 109.0
HFD3_k127_2174666_4 - - - - 0.000000000007042 70.0
HFD3_k127_2191882_0 Peptidase dimerisation domain K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000496 411.0
HFD3_k127_2191882_1 PFAM iron-containing alcohol dehydrogenase K00217 - 1.3.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 344.0
HFD3_k127_2191882_2 Phospholipase/Carboxylesterase K06999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000381 282.0
HFD3_k127_2192953_0 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 440.0
HFD3_k127_2192953_1 Aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 323.0
HFD3_k127_2192953_3 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.00000000000000000000000000000000000000001348 158.0
HFD3_k127_2192953_4 TonB dependent receptor K02014,K16087 - - 0.00000000000000000000000000000000000005294 162.0
HFD3_k127_2214124_0 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 323.0
HFD3_k127_2214124_1 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000002084 237.0
HFD3_k127_2220439_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 428.0
HFD3_k127_2220439_1 Biotin-lipoyl like K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 392.0
HFD3_k127_2220439_2 Outer membrane efflux protein K12340 - - 0.000000000000000000001899 94.0
HFD3_k127_2224142_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 6.693e-319 986.0
HFD3_k127_2224142_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 314.0
HFD3_k127_2224142_2 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007772 267.0
HFD3_k127_2224142_3 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.000000000000000000006551 93.0
HFD3_k127_2227962_0 Cupin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 319.0
HFD3_k127_2227962_1 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000004947 205.0
HFD3_k127_2227962_2 Histidine kinase K07675 - 2.7.13.3 0.000000000000000000101 92.0
HFD3_k127_2232177_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 7.673e-242 756.0
HFD3_k127_2232177_1 tRNA (Uracil-5-)-methyltransferase K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004952 410.0
HFD3_k127_2232177_2 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 322.0
HFD3_k127_2232177_3 Biotin-requiring enzyme - - - 0.0000000001615 65.0
HFD3_k127_2260705_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 347.0
HFD3_k127_2260705_1 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006493 338.0
HFD3_k127_2260705_2 Acyl transferase domain K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002092 277.0
HFD3_k127_2260705_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000000000033 139.0
HFD3_k127_228577_0 Biotin-lipoyl like K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003592 453.0
HFD3_k127_228577_1 Outer membrane efflux protein K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 411.0
HFD3_k127_228577_2 creatininase K01470,K22232 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008701 293.0
HFD3_k127_2291686_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1064.0
HFD3_k127_2291686_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 1.196e-209 656.0
HFD3_k127_2291686_2 self proteolysis - - - 0.00000000000000000000001034 112.0
HFD3_k127_2312493_0 peptidase - - - 1.665e-216 685.0
HFD3_k127_2312493_1 amino acid K20265 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0006873,GO:0006885,GO:0008150,GO:0008509,GO:0008514,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0019725,GO:0022804,GO:0022857,GO:0030003,GO:0030004,GO:0030641,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0045852,GO:0046942,GO:0046943,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0051454,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:0098771,GO:1902475,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006071 462.0
HFD3_k127_2312493_2 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 417.0
HFD3_k127_2312493_3 Tryptophan-rich sensory protein K05770 - - 0.00000000000000000000000000000000000000000000000000000000000009873 216.0
HFD3_k127_2312493_4 DinB family - - - 0.000000000000000000000000000000000000000000000000000003096 197.0
HFD3_k127_2312493_5 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000005728 156.0
HFD3_k127_2312493_6 ketosteroid isomerase - - - 0.0000000007846 66.0
HFD3_k127_2321607_0 Penicillin binding protein transpeptidase domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 595.0
HFD3_k127_2321607_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000003731 145.0
HFD3_k127_2321607_2 - - - - 0.00001507 49.0
HFD3_k127_2335449_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 481.0
HFD3_k127_2335449_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 482.0
HFD3_k127_2335449_2 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 432.0
HFD3_k127_2335449_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000001049 195.0
HFD3_k127_2345932_0 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004155 458.0
HFD3_k127_2345932_1 HEAT repeats - - - 0.000000000000000000000000000000000000000006728 157.0
HFD3_k127_2349943_0 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 379.0
HFD3_k127_2349943_1 Transglycosylase K21464 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 305.0
HFD3_k127_2349943_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000008376 199.0
HFD3_k127_2349943_3 - - - - 0.0000000001004 63.0
HFD3_k127_2354253_0 Sigma-54 interaction domain K07715 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000454 399.0
HFD3_k127_2359086_0 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 420.0
HFD3_k127_2359086_1 cheY-homologous receiver domain - - - 0.00000000000000000000003167 99.0
HFD3_k127_2363576_0 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007784 440.0
HFD3_k127_2363576_1 Domain of unknown function (DUF4974) K07165 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001045 281.0
HFD3_k127_2363576_2 ECF sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000000000000000002791 222.0
HFD3_k127_2363576_3 - - - - 0.00000000000000000000000000000000000000000000000000000007626 207.0
HFD3_k127_2363576_4 Peptidase family M3 K01284 - 3.4.15.5 0.00000000000000000000000000000000000000000000578 165.0
HFD3_k127_2363576_5 - - - - 0.0000000000000000000000000000000000226 143.0
HFD3_k127_2363891_0 PFAM Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 301.0
HFD3_k127_2363891_1 Peptidase m28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001474 246.0
HFD3_k127_2368003_0 Aldehyde dehydrogenase family K00128,K00130 - 1.2.1.3,1.2.1.8 1.196e-239 749.0
HFD3_k127_2368003_1 DeoC/LacD family aldolase - - - 0.00000000000000000000000000000000000000000000000000000000000000218 219.0
HFD3_k127_2368003_2 SnoaL-like domain - - - 0.00000000000004565 78.0
HFD3_k127_2374414_0 Domain of unknown function (DUF2172) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 574.0
HFD3_k127_2374414_1 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008514 514.0
HFD3_k127_2374414_2 aminoglycoside 3-N-acetyltransferase activity K00662 - 2.3.1.81 0.0000000000000000000000000005491 130.0
HFD3_k127_2374414_4 KR domain - - - 0.0000000000000001426 81.0
HFD3_k127_2379145_0 Fumarylacetoacetate (FAA) hydrolase K01555 - 3.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009715 569.0
HFD3_k127_2379145_1 histidine-tRNA ligase activity K01892,K02502 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000967 226.0
HFD3_k127_2379145_2 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.000000000000000000000000208 108.0
HFD3_k127_2391150_0 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - 1.226e-267 854.0
HFD3_k127_2391150_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000004981 90.0
HFD3_k127_2400429_0 P2 response regulator binding domain K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009143 277.0
HFD3_k127_2400429_1 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000000215 144.0
HFD3_k127_2402727_0 TonB dependent receptor - - - 5.784e-274 869.0
HFD3_k127_2402727_1 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001895 284.0
HFD3_k127_2402727_2 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000001891 123.0
HFD3_k127_2402727_3 PQQ-like domain K05889 - 1.1.2.6 0.000000000003674 70.0
HFD3_k127_2416027_0 Oxidoreductase family, C-terminal alpha/beta domain K13020 - 1.1.1.335 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 542.0
HFD3_k127_2416027_1 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 408.0
HFD3_k127_2416027_2 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 284.0
HFD3_k127_2416027_3 Hexapeptide repeat of succinyl-transferase K13018 - 2.3.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007537 271.0
HFD3_k127_2420287_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005076 525.0
HFD3_k127_2420287_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 518.0
HFD3_k127_2420287_2 Cell cycle protein K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 469.0
HFD3_k127_2420287_3 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 428.0
HFD3_k127_2420287_4 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 293.0
HFD3_k127_2420287_5 Cell division protein FtsQ K03589 - - 0.000000000000000000000000000000000000000000006966 172.0
HFD3_k127_2420287_6 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000008668 66.0
HFD3_k127_2420389_0 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000002491 262.0
HFD3_k127_2443548_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 457.0
HFD3_k127_2443548_1 Glycosyl transferase family 2 K08301 - - 0.00000000000000000000000000000000000000000000000000000000001277 211.0
HFD3_k127_2443548_2 gamma-glutamyl-gamma-aminobutyrate hydrolase activity K07010 - - 0.00000000000000000000000000000000000000000000000000000004803 205.0
HFD3_k127_2443548_3 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000003702 203.0
HFD3_k127_2443548_4 POT family K03305 - - 0.000000000000000000000000000000000000000000000004119 175.0
HFD3_k127_2452570_0 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000009539 226.0
HFD3_k127_2452570_1 - - - - 0.000000000000000000000000000000000000000000043 169.0
HFD3_k127_2464850_0 Belongs to the bacterial solute-binding protein 9 family - - - 0.000000000000000000000000000000000000000000000000000000000000000002224 245.0
HFD3_k127_2487542_0 Insulinase (Peptidase family M16) K07263 - - 2e-322 1018.0
HFD3_k127_2487542_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000774 467.0
HFD3_k127_2487542_10 VKc - - - 0.0000000000000000007465 92.0
HFD3_k127_2487542_11 Zinc metalloprotease (Elastase) - - - 0.00002392 56.0
HFD3_k127_2487542_2 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 325.0
HFD3_k127_2487542_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K19340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005374 306.0
HFD3_k127_2487542_4 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000000001456 227.0
HFD3_k127_2487542_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000008402 195.0
HFD3_k127_2487542_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.000000000000000000000000000000000001506 145.0
HFD3_k127_2487542_7 - - - - 0.00000000000000000000000126 106.0
HFD3_k127_2488604_0 protein histidine kinase activity - - - 1.019e-320 1000.0
HFD3_k127_2488604_1 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000003262 199.0
HFD3_k127_2488604_2 Histidine kinase - - - 0.0000000001394 66.0
HFD3_k127_2492239_0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 500.0
HFD3_k127_2492239_1 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 289.0
HFD3_k127_2492239_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000002188 252.0
HFD3_k127_2492239_3 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000935 213.0
HFD3_k127_2492239_4 Domain of unknown function (DUF892) - - - 0.000000000000000000000000000000000000000000000000008117 185.0
HFD3_k127_2492239_5 - - - - 0.0000000000000000000000000000000009149 133.0
HFD3_k127_2503895_0 Cytidylyltransferase - - - 0.000000000000000000000000000000000000000000000000000000004834 205.0
HFD3_k127_2503895_1 PFAM oxidoreductase domain protein K09949 - - 0.0000000000000000000000000003094 126.0
HFD3_k127_2521137_0 Ftsk_gamma K03466 - - 4.271e-267 844.0
HFD3_k127_2521137_1 2-phosphosulpholactate phosphatase K05979 - 3.1.3.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 290.0
HFD3_k127_253602_0 Cytochrome c K07243 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 337.0
HFD3_k127_253602_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004145 310.0
HFD3_k127_253602_2 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003493 283.0
HFD3_k127_253602_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005463 269.0
HFD3_k127_253602_4 CYTH domain K01768,K05873 - 4.6.1.1 0.0000000000000000000000000000000000000000000007005 172.0
HFD3_k127_253602_6 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000005159 70.0
HFD3_k127_2543398_0 Tricorn protease homolog - - - 1.211e-297 936.0
HFD3_k127_2543398_1 Putative esterase - - - 0.000000000002582 71.0
HFD3_k127_2562157_0 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007947 332.0
HFD3_k127_2562157_1 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 313.0
HFD3_k127_2562157_2 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 316.0
HFD3_k127_2562157_3 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000559 258.0
HFD3_k127_2562157_4 Zn peptidase - - - 0.000000000000000000000000000000000000000000000000000000001378 209.0
HFD3_k127_2562157_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000000000000000002008 115.0
HFD3_k127_2562157_6 Adenosine/AMP deaminase K01488 - 3.5.4.4 0.00008326 45.0
HFD3_k127_2582611_0 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006997 343.0
HFD3_k127_2582611_1 COG3911 Predicted ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005268 251.0
HFD3_k127_2582611_2 PFAM CBS domain - - - 0.00000000001565 73.0
HFD3_k127_2582611_3 Universal stress protein - - - 0.0000002459 63.0
HFD3_k127_2582611_4 - - - - 0.000003109 56.0
HFD3_k127_2582611_5 FtsX-like permease family K02004 - - 0.0001211 45.0
HFD3_k127_2592314_0 Prolyl oligopeptidase - - - 1.709e-229 734.0
HFD3_k127_2592314_1 EVE domain - - - 0.00000000000000000000000000000000000000000000000000000000004014 210.0
HFD3_k127_2592314_2 MarR family - - - 0.00000000000000000000000000000000000000000000000000000001163 203.0
HFD3_k127_2592314_3 YGGT family K02221 - - 0.000000000000000000000000000000000000000000000001939 183.0
HFD3_k127_2592314_4 Proposed role in polysaccahride synthesis K07077 - - 0.00000000000000000000000000000000000001729 144.0
HFD3_k127_2592314_5 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000003077 113.0
HFD3_k127_2592314_6 Belongs to the UPF0235 family K09131 - - 0.0000000000000000004899 93.0
HFD3_k127_2601042_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005622 535.0
HFD3_k127_2601042_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 353.0
HFD3_k127_2601042_2 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 353.0
HFD3_k127_2601042_3 - - - - 0.000000000000000000000000000000000000000000000002442 188.0
HFD3_k127_2601042_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000003783 59.0
HFD3_k127_2601042_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0005722 53.0
HFD3_k127_2609871_0 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000001879 173.0
HFD3_k127_2609871_1 heptosyltransferase K02843 - - 0.000000000000001754 88.0
HFD3_k127_2622544_0 Tetratricopeptide repeat K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 376.0
HFD3_k127_2622544_1 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 350.0
HFD3_k127_2622544_2 cyanophycin synthetase K03802 - 6.3.2.29,6.3.2.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000216 282.0
HFD3_k127_2622544_3 DNA-templated transcription, initiation K02405 - - 0.0000000000000000000000000000000000000000000000002917 186.0
HFD3_k127_2622544_4 domain protein K13735 - - 0.000000007602 67.0
HFD3_k127_2635799_0 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004134 417.0
HFD3_k127_2635799_1 DNA restriction-modification system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 345.0
HFD3_k127_2635799_2 SNF2 family N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 320.0
HFD3_k127_2644068_0 Sortilin, neurotensin receptor 3, - - - 0.0 1090.0
HFD3_k127_2644068_1 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 494.0
HFD3_k127_2644068_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007213 250.0
HFD3_k127_2644068_3 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000002173 190.0
HFD3_k127_2644068_4 ABC1 family - - - 0.000000000000000000000000000000000000000000000001118 180.0
HFD3_k127_2644068_5 AntiSigma factor - - - 0.000000000000000000000000000000000000003941 154.0
HFD3_k127_2644068_6 DinB superfamily - - - 0.00000000000000000000000000000000002155 144.0
HFD3_k127_2644068_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000001052 137.0
HFD3_k127_2644068_8 ketosteroid isomerase - - - 0.00000002304 63.0
HFD3_k127_2672693_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 5.627e-273 851.0
HFD3_k127_2672693_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 371.0
HFD3_k127_2673834_0 PFAM Glycosyl transferase family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 348.0
HFD3_k127_2676465_0 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 360.0
HFD3_k127_2676465_1 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003653 311.0
HFD3_k127_2676465_2 helix_turn _helix lactose operon repressor K02529 - - 0.0000000000000000000000000000000000000000000003295 169.0
HFD3_k127_2682954_0 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 469.0
HFD3_k127_268533_0 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 2.838e-283 884.0
HFD3_k127_2688836_0 Electron transfer flavoprotein domain K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006868 426.0
HFD3_k127_2688836_1 oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor K00311 GO:0003674,GO:0003824,GO:0004174,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016645,GO:0016649,GO:0016722,GO:0017133,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031304,GO:0031305,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032592,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043783,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045251,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070013,GO:0098573,GO:0098798,GO:1902494,GO:1990204 1.5.5.1 0.0000000000000000000000000000000000000000000000000005591 189.0
HFD3_k127_2698680_0 Domain of unknown function (DUF3471) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004577 509.0
HFD3_k127_2698680_1 PFAM D-aminoacylase, C-terminal region K06015 - 3.5.1.81 0.000000000000000000000000000000000001855 139.0
HFD3_k127_2701611_0 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000002905 201.0
HFD3_k127_2701611_1 luxR family - - - 0.000000000000000000000000000000000000003362 156.0
HFD3_k127_2701611_2 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000003764 140.0
HFD3_k127_2701611_3 - - - - 0.00000000000000000000000000000000004713 142.0
HFD3_k127_2701611_5 peptidase K01415,K07386 - 3.4.24.71 0.000000000000000008223 86.0
HFD3_k127_2708147_0 Capsule assembly protein Wzi - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002823 265.0
HFD3_k127_2708147_1 Capsule assembly protein Wzi - - - 0.00000000000000000000000000000000000000000000000000002374 207.0
HFD3_k127_2708147_2 PFAM Glycosyl transferase family 4 K02851,K13007 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000001083 134.0
HFD3_k127_2708147_3 Modulates the polysaccharide chain length of enterobacterial common antigen (ECA) - - - 0.000000000000000000003037 107.0
HFD3_k127_2726402_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2272.0
HFD3_k127_2730821_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007825 469.0
HFD3_k127_2730821_1 arylformamidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009898 295.0
HFD3_k127_2730821_2 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001279 280.0
HFD3_k127_2730821_3 Belongs to the BI1 family K06890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001752 271.0
HFD3_k127_2730821_4 HAD-hyrolase-like K06019 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000007335 234.0
HFD3_k127_2730821_5 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000004485 175.0
HFD3_k127_2730821_6 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000000506 124.0
HFD3_k127_2730821_7 Large extracellular alpha-helical protein K13735 - - 0.0000007562 61.0
HFD3_k127_2735131_0 GMC oxidoreductase - - - 2.736e-300 928.0
HFD3_k127_2735131_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 416.0
HFD3_k127_2735131_2 Gluconate 2-dehydrogenase subunit 3 - - - 0.0000000000000000000000000000000000000000000000000000003189 201.0
HFD3_k127_2737880_0 DNA topoisomerase type I activity K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 384.0
HFD3_k127_2737880_1 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000103 245.0
HFD3_k127_2737880_2 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 0.00000000000000000000000000000009414 132.0
HFD3_k127_2746294_0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000001269 258.0
HFD3_k127_2746294_1 Outer membrane efflux protein K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003807 258.0
HFD3_k127_2746294_2 ECF sigma factor K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000006079 226.0
HFD3_k127_2746294_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000004382 149.0
HFD3_k127_2746294_4 - - - - 0.0002033 49.0
HFD3_k127_2767166_0 TonB-dependent receptor - - - 1.582e-207 667.0
HFD3_k127_2767166_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 315.0
HFD3_k127_2778682_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 329.0
HFD3_k127_2778682_1 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005498 273.0
HFD3_k127_2778682_2 Psort location Cytoplasmic, score K00945 - 2.7.4.25 0.000000000000000000000000000305 122.0
HFD3_k127_2778682_3 Threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000007977 115.0
HFD3_k127_2783842_0 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 469.0
HFD3_k127_2783842_1 PFAM Amidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 363.0
HFD3_k127_2783842_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001683 226.0
HFD3_k127_2785257_0 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001535 249.0
HFD3_k127_2785257_1 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000000000000000000000000000000005661 191.0
HFD3_k127_2785257_2 DinB family - - - 0.000000000000000000002005 96.0
HFD3_k127_2788325_0 Cellulose biosynthesis protein BcsQ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004257 392.0
HFD3_k127_2788325_1 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 377.0
HFD3_k127_2788325_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000002647 186.0
HFD3_k127_2788325_3 - - - - 0.0000000000000000001308 102.0
HFD3_k127_2788325_4 Phosphoribosyl transferase domain K07101 - - 0.0000000000000128 74.0
HFD3_k127_2803591_0 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007546 369.0
HFD3_k127_2803591_1 transcriptional regulators - - - 0.00000000000000000000006617 104.0
HFD3_k127_2803591_2 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000004674 86.0
HFD3_k127_2817743_0 WD40-like Beta Propeller Repeat - - - 1.288e-207 669.0
HFD3_k127_2825800_0 Cys/Met metabolism PLP-dependent enzyme K01758 - 4.4.1.1 5.674e-197 619.0
HFD3_k127_2825800_1 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006486 328.0
HFD3_k127_2825800_2 Endonuclease Exonuclease Phosphatase - - - 0.0000001174 57.0
HFD3_k127_2831037_0 Binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000000000000000000000000000000000005105 228.0
HFD3_k127_2831037_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000007323 237.0
HFD3_k127_2831037_2 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000000000000002741 172.0
HFD3_k127_2831037_3 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000000000000001002 164.0
HFD3_k127_2831037_4 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000000003158 114.0
HFD3_k127_2831037_5 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000001302 111.0
HFD3_k127_2854283_0 long-chain fatty acid transporting porin activity K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 470.0
HFD3_k127_2854283_1 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004629 457.0
HFD3_k127_2854283_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000004653 226.0
HFD3_k127_2854283_3 glyoxalase III activity - - - 0.000000000000000000327 88.0
HFD3_k127_2854319_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 312.0
HFD3_k127_2854319_1 Protein of unknown function (DUF1697) - - - 0.00000000000000000000000000000000000000000000008941 175.0
HFD3_k127_2854319_2 leukotriene A-4 hydrolase - - - 0.000000000000000000000000000000000000000001872 162.0
HFD3_k127_2855376_0 cellulose binding - - - 0.0 1180.0
HFD3_k127_2855376_1 ABC transporter K06020 - 3.6.3.25 7.898e-256 799.0
HFD3_k127_2855376_10 - - - - 0.00000000000000000000000000000000000000009213 154.0
HFD3_k127_2855376_11 Cysteine-rich CPXCG - - - 0.00000000000000249 89.0
HFD3_k127_2855376_12 - - - - 0.000008902 55.0
HFD3_k127_2855376_2 FAD dependent oxidoreductase - - - 1.99e-209 666.0
HFD3_k127_2855376_3 BAAT / Acyl-CoA thioester hydrolase C terminal K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 505.0
HFD3_k127_2855376_4 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 449.0
HFD3_k127_2855376_5 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 337.0
HFD3_k127_2855376_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000444 287.0
HFD3_k127_2855376_7 Protein of unknown function (DUF1810) - - - 0.000000000000000000000000000000000000000000000000000006793 194.0
HFD3_k127_2855376_8 cellulose binding - - - 0.00000000000000000000000000000000000000000003951 166.0
HFD3_k127_2855376_9 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000752 155.0
HFD3_k127_2862251_0 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000669 178.0
HFD3_k127_2862251_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000001344 154.0
HFD3_k127_2896780_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008574 436.0
HFD3_k127_2896780_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 299.0
HFD3_k127_2896780_2 PFAM peptidase - - - 0.00000000000000000000000000000006686 133.0
HFD3_k127_290510_0 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 592.0
HFD3_k127_290510_1 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000597 567.0
HFD3_k127_290510_2 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007125 355.0
HFD3_k127_290510_3 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000002901 214.0
HFD3_k127_2911609_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 359.0
HFD3_k127_2911609_1 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000474 264.0
HFD3_k127_2912151_0 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003394 285.0
HFD3_k127_2912151_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800,K00945 - 2.5.1.19,2.7.4.25 0.00000000000000000000000000000000000000000007418 165.0
HFD3_k127_2912151_2 Psort location CytoplasmicMembrane, score - - - 0.00006219 47.0
HFD3_k127_2920828_0 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005167 455.0
HFD3_k127_2920828_1 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000005551 260.0
HFD3_k127_2927890_0 4 iron, 4 sulfur cluster binding K03737 - 1.2.7.1 1.905e-202 645.0
HFD3_k127_2932242_0 - - - - 0.00000000000000000000000000000000000000000000000000000291 216.0
HFD3_k127_2932242_1 Copper/zinc superoxide dismutase (SODC) K04565 - 1.15.1.1 0.000000000000000000000000000000000000000000001094 171.0
HFD3_k127_2952816_0 3-ketoacyl-coa thiolase, mitochondrial. Source PGD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 397.0
HFD3_k127_2952816_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006061 317.0
HFD3_k127_2952816_2 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 300.0
HFD3_k127_2952816_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000006502 249.0
HFD3_k127_2952816_4 Peptidase dimerisation domain K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000001005 199.0
HFD3_k127_2952816_5 - - - - 0.000000000000000000000000000000000000000000000000000001153 201.0
HFD3_k127_2952816_6 - - - - 0.0000000000000000000000000000000009834 140.0
HFD3_k127_2952816_7 - - - - 0.0000000000004171 72.0
HFD3_k127_2962692_0 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 283.0
HFD3_k127_2962692_1 Domain of unknown function (DUF4956) - - - 0.00000000000000000000000000000000000009559 156.0
HFD3_k127_2962692_2 SdiA-regulated - - - 0.0000000000000000000000000000000000109 147.0
HFD3_k127_2962692_3 acetyltransferase K22441 - 2.3.1.57 0.00000000000000000000000000000000005106 143.0
HFD3_k127_2962692_4 - - - - 0.0000000000000000000000001842 109.0
HFD3_k127_3005451_0 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003022 263.0
HFD3_k127_3005451_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000000005895 151.0
HFD3_k127_3005451_2 OmpA family K03640 - - 0.0000000000000000000000000000001586 130.0
HFD3_k127_3005451_3 Outer membrane lipoprotein - - - 0.0000000000473 73.0
HFD3_k127_3005795_0 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 356.0
HFD3_k127_3005795_1 Beta-eliminating lyase K00639 - 2.3.1.29 0.000000000000000000000000000000000000000001327 159.0
HFD3_k127_3005795_2 NAD(P)H-binding K01784 - 5.1.3.2 0.00000000000000005009 87.0
HFD3_k127_301856_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004392 510.0
HFD3_k127_301856_1 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 477.0
HFD3_k127_301856_2 Protein of unknown function (DUF1343) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000637 407.0
HFD3_k127_301856_3 Domain of Unknown Function (DUF1206) - - - 0.0000000000000000000000000000001306 138.0
HFD3_k127_3020716_0 Enoyl-CoA hydratase/isomerase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 1.88e-229 728.0
HFD3_k127_3020716_1 Thiolase, C-terminal domain K00632 - 2.3.1.16 4.31e-202 636.0
HFD3_k127_3020716_2 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 419.0
HFD3_k127_3020716_3 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 392.0
HFD3_k127_3020716_4 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001517 282.0
HFD3_k127_3020716_5 Transcription elongation factor, N-terminal K03624 - - 0.000000000000000000000000000000000000000000000000000000000000001365 222.0
HFD3_k127_3020806_0 protein catabolic process K03420,K13525,K17681 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006351 389.0
HFD3_k127_3020806_1 Multicopper oxidase K22348 - 1.16.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007271 292.0
HFD3_k127_3049981_0 PFAM peptidase M13 K07386 - - 5.673e-201 646.0
HFD3_k127_3049981_1 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000000000000000298 175.0
HFD3_k127_3049981_2 DinB superfamily - - - 0.00000000000000000000000000000002004 132.0
HFD3_k127_3067258_0 PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004133 399.0
HFD3_k127_3067258_1 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 394.0
HFD3_k127_3067258_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008506 287.0
HFD3_k127_3067258_3 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000002519 261.0
HFD3_k127_3070454_0 diguanylate cyclase K02488 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009181 392.0
HFD3_k127_3082256_0 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001688 265.0
HFD3_k127_3082256_1 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.0000000000000000000000000000000000000000000001018 174.0
HFD3_k127_3089093_0 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001757 280.0
HFD3_k127_3089093_1 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000004906 206.0
HFD3_k127_3089093_2 Lysin motif - - - 0.0000002915 61.0
HFD3_k127_3113748_0 Sodium/hydrogen exchanger family K03455 - - 4.535e-226 720.0
HFD3_k127_3113748_1 KaiC K08482 - - 0.0000000000000000000000000002571 117.0
HFD3_k127_3113748_2 Domain of unknown function (DUF5117) - - - 0.000000000000000000001828 100.0
HFD3_k127_3128106_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 488.0
HFD3_k127_3128106_1 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 379.0
HFD3_k127_3128106_2 ketosteroid isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 358.0
HFD3_k127_3128106_3 - - - - 0.000000000000000000000000000000000000000000000003078 184.0
HFD3_k127_3129514_0 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000005721 214.0
HFD3_k127_3129514_2 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000009852 204.0
HFD3_k127_3129514_3 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.00000000000000148 85.0
HFD3_k127_3129921_0 Clp amino terminal domain, pathogenicity island component K03696 - - 5.992e-298 919.0
HFD3_k127_3129921_1 ATP:guanido phosphotransferase, C-terminal catalytic domain K19405 - 2.7.14.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 546.0
HFD3_k127_3129921_2 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002939 272.0
HFD3_k127_3129921_3 PFAM UvrB UvrC protein K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.0002641 50.0
HFD3_k127_31400_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007979 347.0
HFD3_k127_31400_1 Putative glycosyl hydrolase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004343 267.0
HFD3_k127_31400_2 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000002967 184.0
HFD3_k127_31400_3 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 0.00000000000000000000000000000002018 134.0
HFD3_k127_3150087_0 3-phosphoshikimate 1-carboxyvinyltransferase activity K00800 GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:0071944,GO:1901576 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 454.0
HFD3_k127_3150087_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 398.0
HFD3_k127_3150087_2 Tetrahydrodipicolinate N-succinyltransferase N-terminal K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 394.0
HFD3_k127_3150087_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000238 207.0
HFD3_k127_3150087_4 glycosyl transferase group 1 - - - 0.000000000000000000000000000000008069 138.0
HFD3_k127_3156585_0 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.0000000000000000000000000000000000000000000001326 178.0
HFD3_k127_3156585_1 Uncharacterized conserved protein (DUF2249) - - - 0.0000000000000000000000000000002467 130.0
HFD3_k127_3156585_2 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000003503 91.0
HFD3_k127_3156585_3 - - - - 0.000000000000000007816 85.0
HFD3_k127_3156585_4 Domain of Unknown function (DUF542) K07322 - - 0.00000000008804 64.0
HFD3_k127_3156585_5 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.0001393 44.0
HFD3_k127_3157766_0 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 504.0
HFD3_k127_3157766_1 Putative glycosyl hydrolase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 460.0
HFD3_k127_3157766_2 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000001748 238.0
HFD3_k127_3157766_3 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000000000000000000001289 136.0
HFD3_k127_3157766_4 Acts as a magnesium transporter K06213 GO:0000287,GO:0003674,GO:0005488,GO:0005515,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015693,GO:0030001,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0051179,GO:0051234,GO:0070838,GO:0072511 - 0.0000000000000000000000000000001016 124.0
HFD3_k127_3157766_5 - - - - 0.0000000000000000000004109 107.0
HFD3_k127_3157766_7 mercury ion transmembrane transporter activity K07213 - - 0.000000003503 63.0
HFD3_k127_3158811_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 510.0
HFD3_k127_3158811_1 von Willebrand factor type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 482.0
HFD3_k127_3158811_2 Protein of unknown function (DUF1194) K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 340.0
HFD3_k127_3197210_0 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 2.452e-217 691.0
HFD3_k127_3197210_1 Cell cycle protein K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 516.0
HFD3_k127_3197210_2 rod shape-determining protein MreD K03571 - - 0.0000000000000000000000000000000000000000000000000000000007302 206.0
HFD3_k127_3197210_3 rod shape-determining protein MreC K03570 - - 0.000000000000000000000094 104.0
HFD3_k127_320260_0 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008638 448.0
HFD3_k127_320260_1 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 383.0
HFD3_k127_320260_2 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 381.0
HFD3_k127_320260_3 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.0000000000000000000000000003233 116.0
HFD3_k127_3205226_0 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005125 439.0
HFD3_k127_3205226_1 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 400.0
HFD3_k127_3205226_2 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001323 301.0
HFD3_k127_3214397_0 cellulose binding - - - 0.0 1143.0
HFD3_k127_3214397_1 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 334.0
HFD3_k127_3214397_2 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000000000000000000000000000004671 219.0
HFD3_k127_3217958_0 Sigma-70 region 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 591.0
HFD3_k127_3217958_1 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008749 342.0
HFD3_k127_3231721_0 hydrolase activity, acting on glycosyl bonds - - - 5e-324 1008.0
HFD3_k127_3231721_1 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000003857 218.0
HFD3_k127_3231721_2 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000002362 161.0
HFD3_k127_3311494_0 Acyclic terpene utilisation family protein AtuA - - - 0.00000000000000000000000000000000000000000000000000000000000001871 216.0
HFD3_k127_3311494_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00824 - 2.6.1.21 0.0000000000000000000000000000000000000000000000000000000000003687 222.0
HFD3_k127_3311494_2 - - - - 0.0000000000000000000000000000000000000000000000007122 183.0
HFD3_k127_3313757_0 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 453.0
HFD3_k127_3313757_1 KaiC K08482 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 407.0
HFD3_k127_3331658_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006748 526.0
HFD3_k127_3331658_1 Ribosomal protein S2 K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006453 447.0
HFD3_k127_3331658_10 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000672 94.0
HFD3_k127_3331658_11 Ribosomal protein S9/S16 K02996 - - 0.0000000000006459 68.0
HFD3_k127_3331658_2 Peptidase family M50 K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008768 406.0
HFD3_k127_3331658_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003976 349.0
HFD3_k127_3331658_4 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 314.0
HFD3_k127_3331658_5 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003407 264.0
HFD3_k127_3331658_6 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000000000000002997 237.0
HFD3_k127_3331658_7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000001636 230.0
HFD3_k127_3331658_8 Biotin-requiring enzyme - - - 0.00000000000000000000000000000000000001298 146.0
HFD3_k127_3331658_9 Ribosomal protein S9/S16 K02996 - - 0.0000000000000000000000000000000000002705 141.0
HFD3_k127_3334332_0 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007343 275.0
HFD3_k127_3334332_1 Fe-S metabolism associated domain K02426 - - 0.000000000000000000000000000000000000000000000000002774 184.0
HFD3_k127_3334332_2 - - - - 0.0000000000000000000000001348 111.0
HFD3_k127_3334332_3 - - - - 0.00000000003904 65.0
HFD3_k127_3345926_0 COG3119 Arylsulfatase A K01137 - 3.1.6.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 487.0
HFD3_k127_3345926_1 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000002318 241.0
HFD3_k127_3345926_2 Protein of unknown function (DUF1460) - - - 0.000000000000000000000000000000000000000000000000006985 194.0
HFD3_k127_3365667_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 6.523e-313 969.0
HFD3_k127_3365667_1 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 304.0
HFD3_k127_3365667_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000702 254.0
HFD3_k127_3365667_3 Transglycosylase SLT domain K08309 - - 0.000000000000000000000000000000000000006762 166.0
HFD3_k127_3365667_4 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000009139 142.0
HFD3_k127_3365667_5 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.0000000000000000000000000000000000009765 145.0
HFD3_k127_3392035_0 Pyrimidine nucleoside phosphorylase C-terminal domain K00756 - 2.4.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 585.0
HFD3_k127_3392035_1 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 352.0
HFD3_k127_3392035_2 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000003278 233.0
HFD3_k127_3392035_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000004894 239.0
HFD3_k127_3393571_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007862 539.0
HFD3_k127_3393571_1 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006968 407.0
HFD3_k127_3393571_2 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000008487 246.0
HFD3_k127_3393571_3 Domain of unknown function (DUF892) - - - 0.00000000000000000000000000000000000000000000005596 176.0
HFD3_k127_3393571_4 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 0.000000000000000000000000000006668 122.0
HFD3_k127_3393571_5 Hsp20/alpha crystallin family - - - 0.00000000000000000000000002564 115.0
HFD3_k127_3393571_6 Protein of unknown function (DUF541) K09807 - - 0.0000000000000000008527 97.0
HFD3_k127_3393571_7 Peroxiredoxin K03564 - 1.11.1.15 0.000000000000001036 78.0
HFD3_k127_3393571_9 - - - - 0.00002911 49.0
HFD3_k127_3433084_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1096.0
HFD3_k127_3433084_1 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000000000000000000000001227 220.0
HFD3_k127_3433084_2 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925,K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000003099 194.0
HFD3_k127_3433084_3 Glycoprotease family K14742 - - 0.0000000000000000000000000000000000000000000006077 174.0
HFD3_k127_3433084_4 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000000000000000000000000002993 140.0
HFD3_k127_3433084_5 Lysin motif - - - 0.00000000000006363 78.0
HFD3_k127_3435803_0 chlorophyll binding K02557,K03286 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006048 302.0
HFD3_k127_3435803_1 Protein conserved in bacteria - - - 0.000000000000000002714 92.0
HFD3_k127_3437973_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000074 258.0
HFD3_k127_3437973_1 phosphinothricin N-acetyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000001182 216.0
HFD3_k127_3437973_2 ECF sigma factor K03088 - - 0.000000000000000000000000000000000000005809 153.0
HFD3_k127_3437973_3 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000004324 136.0
HFD3_k127_3437973_4 - - - - 0.000000000000000000001602 95.0
HFD3_k127_3437973_6 Anti-sigma-K factor rskA - - - 0.000000004255 68.0
HFD3_k127_3444808_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 9.399e-234 734.0
HFD3_k127_3444808_1 TonB-dependent Receptor Plug K16092 - - 0.000001098 57.0
HFD3_k127_3444808_2 - - - - 0.0002643 43.0
HFD3_k127_3458972_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009433 243.0
HFD3_k127_3473798_0 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 318.0
HFD3_k127_3473798_1 - - - - 0.000000000000000000000000000000000000000002966 177.0
HFD3_k127_3473798_2 - - - - 0.0000000000000000000000000000000003076 139.0
HFD3_k127_3473798_3 Methyltransferase FkbM domain - - - 0.000001289 53.0
HFD3_k127_349350_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1.341e-221 697.0
HFD3_k127_349350_1 Phage integrase, N-terminal SAM-like domain K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 430.0
HFD3_k127_349350_2 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 423.0
HFD3_k127_349350_3 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000425 337.0
HFD3_k127_349350_4 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 302.0
HFD3_k127_349350_5 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005369 284.0
HFD3_k127_349350_7 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000007509 53.0
HFD3_k127_3504052_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 0.0 1140.0
HFD3_k127_3504992_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000001538 179.0
HFD3_k127_3504992_1 homoserine dehydrogenase K00003 - 1.1.1.3 0.00003359 51.0
HFD3_k127_3544195_0 Peptidase dimerisation domain K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 287.0
HFD3_k127_3544195_2 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000001174 205.0
HFD3_k127_3557557_0 Bacterial transcriptional activator domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000003597 196.0
HFD3_k127_3571885_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 2.416e-237 742.0
HFD3_k127_3571885_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 503.0
HFD3_k127_3571885_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004518 498.0
HFD3_k127_3571885_3 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 387.0
HFD3_k127_3571885_4 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 362.0
HFD3_k127_3589925_0 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 493.0
HFD3_k127_3589925_1 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005358 266.0
HFD3_k127_3603976_0 Polysaccharide biosynthesis/export protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 511.0
HFD3_k127_3603976_1 Glycosyl transferase family 2 K07011 - - 0.0000000000000000000000000000000000000000002684 173.0
HFD3_k127_3603976_2 Modulates the polysaccharide chain length of enterobacterial common antigen (ECA) - - - 0.0000000000000000000000000008951 127.0
HFD3_k127_3614762_0 Mur ligase family, glutamate ligase domain K03802 - 6.3.2.29,6.3.2.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 546.0
HFD3_k127_3614762_1 RimK-like ATP-grasp domain K03802 - 6.3.2.29,6.3.2.30 0.000000000000000000000000000000000005802 151.0
HFD3_k127_3619763_0 - - - - 0.000000000000000000000000000000000000000003987 168.0
HFD3_k127_3619763_1 FR47-like protein K03825 - - 0.00000000000000000000000000000000000008888 149.0
HFD3_k127_3654052_0 oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor K00311 GO:0003674,GO:0003824,GO:0004174,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016645,GO:0016649,GO:0016722,GO:0017133,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031304,GO:0031305,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032592,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043783,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045251,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070013,GO:0098573,GO:0098798,GO:1902494,GO:1990204 1.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 518.0
HFD3_k127_3654052_1 Lysine methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000002378 220.0
HFD3_k127_3662766_0 Carboxyl transferase domain - - - 3.442e-266 829.0
HFD3_k127_3662766_1 Acyclic terpene utilisation family protein AtuA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 532.0
HFD3_k127_3662766_2 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000005339 155.0
HFD3_k127_3665052_0 Elongation factor G C-terminus K06207 - - 2.933e-312 965.0
HFD3_k127_3665052_1 PFAM phospholipase Carboxylesterase - - - 0.0000000000000000000000000000000000000000000000000003192 190.0
HFD3_k127_3669550_0 permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004924 432.0
HFD3_k127_3669550_1 Serine dehydratase alpha chain K01752 - 4.3.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 349.0
HFD3_k127_3669550_2 PspA/IM30 family K03969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 319.0
HFD3_k127_3669550_3 Belongs to the ABC transporter superfamily K02052 - - 0.0000000000000003341 87.0
HFD3_k127_3679090_0 Methylmalonyl-CoA mutase K01848,K11942 - 5.4.99.13,5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 594.0
HFD3_k127_3679090_1 ArgK protein K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 481.0
HFD3_k127_3679090_2 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000003646 161.0
HFD3_k127_3679090_3 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000001687 142.0
HFD3_k127_3681756_0 Bacterial membrane protein YfhO - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 528.0
HFD3_k127_3681756_1 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005765 368.0
HFD3_k127_3681756_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001315 282.0
HFD3_k127_3681756_3 Tetratricopeptide repeat-like domain - - - 0.00000000000000000000000000000168 128.0
HFD3_k127_3689247_0 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 366.0
HFD3_k127_3689247_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000004402 189.0
HFD3_k127_3689247_2 - - - - 0.000000000000000001227 97.0
HFD3_k127_369031_0 Arginosuccinate synthase K01940 - 6.3.4.5 6.008e-218 681.0
HFD3_k127_369031_1 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 505.0
HFD3_k127_369031_10 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.0000000000000000000000000000000000000000000000000000007572 201.0
HFD3_k127_369031_11 Regulates arginine biosynthesis genes K03402 - - 0.00000000000000000000000000000000000000000000000000002684 192.0
HFD3_k127_369031_12 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000000000000000000000000000000003905 137.0
HFD3_k127_369031_13 - - - - 0.0000000000000000000000000000000001846 141.0
HFD3_k127_369031_14 cell redox homeostasis - - - 0.00000000000002406 76.0
HFD3_k127_369031_2 Fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007775 466.0
HFD3_k127_369031_3 cell redox homeostasis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009359 447.0
HFD3_k127_369031_4 Aldo Keto reductase K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003723 379.0
HFD3_k127_369031_5 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 360.0
HFD3_k127_369031_6 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 299.0
HFD3_k127_369031_7 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000002632 251.0
HFD3_k127_369031_8 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000007126 210.0
HFD3_k127_369031_9 cyclic nucleotide binding K07001,K10914 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0030551,GO:0030552,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000006733 208.0
HFD3_k127_3693738_0 HELICc2 K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 361.0
HFD3_k127_3693738_1 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000034 281.0
HFD3_k127_3693738_2 Aminotransferase class I and II K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000008118 168.0
HFD3_k127_3724751_0 Surface antigen K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 589.0
HFD3_k127_3724751_1 Clp amino terminal domain, pathogenicity island component K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003034 530.0
HFD3_k127_3729941_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008162 544.0
HFD3_k127_3729941_1 Aminotransferase class-V K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 417.0
HFD3_k127_3729941_2 GlcNAc-PI de-N-acetylase K01463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 352.0
HFD3_k127_3729941_3 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 0.000000000000000000000000000000000000000000000000005116 190.0
HFD3_k127_3736545_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 574.0
HFD3_k127_3736545_1 protein histidine kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 375.0
HFD3_k127_3736545_2 Protein of unknown function (DUF4242) - - - 0.0000000000000000000000000006112 116.0
HFD3_k127_3736545_3 Methyltransferase - - - 0.00000000000000000000004934 110.0
HFD3_k127_3736545_4 Nodulation protein S (NodS) - - - 0.000000000000000001402 89.0
HFD3_k127_3736545_5 Predicted membrane protein (DUF2339) - - - 0.0000000000000004496 92.0
HFD3_k127_3752354_0 Dehydrogenase - - - 0.0 1003.0
HFD3_k127_3752354_1 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 4.504e-248 775.0
HFD3_k127_3752354_2 Multicopper oxidase K22348 - 1.16.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005378 447.0
HFD3_k127_3752354_3 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.00000000000000000000000000000000000000000000002524 177.0
HFD3_k127_3752354_4 - - - - 0.00000000000000000000000000000001414 132.0
HFD3_k127_3752354_5 - - - - 0.00000000000000000000000000000006165 136.0
HFD3_k127_3752354_6 ketosteroid isomerase - - - 0.00000000000000000000001032 111.0
HFD3_k127_3752354_8 Stress-responsive transcriptional regulator - - - 0.000000000000000005249 85.0
HFD3_k127_3787348_0 Putative zinc-binding metallo-peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000791 304.0
HFD3_k127_3787348_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000201 295.0
HFD3_k127_3787348_2 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000006716 262.0
HFD3_k127_3787348_3 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - - 0.00000000000000000000000000000000000000000000000000000000000002716 226.0
HFD3_k127_3787348_4 - - - - 0.00001542 50.0
HFD3_k127_3787855_0 Tetratricopeptide repeat K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000004296 266.0
HFD3_k127_3787855_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000267 165.0
HFD3_k127_380019_0 COG0433 Predicted ATPase K06915 - - 3.425e-317 982.0
HFD3_k127_380019_1 Calcineurin-like phosphoesterase superfamily domain K03547 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008456 414.0
HFD3_k127_380019_2 AAA domain K03546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004693 244.0
HFD3_k127_380019_3 - - - - 0.000000000000000000000000002619 122.0
HFD3_k127_380019_4 COGs COG2380 conserved - - - 0.000000000000000000002608 94.0
HFD3_k127_3821222_0 Glycosyltransferase family 9 (heptosyltransferase) K12982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 439.0
HFD3_k127_3821222_1 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000301 239.0
HFD3_k127_3821222_2 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000000000000000000001831 217.0
HFD3_k127_3829671_0 ABC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008373 288.0
HFD3_k127_3829671_1 YCII-related domain - - - 0.0000000000000000000000000000000003387 134.0
HFD3_k127_3854038_0 Sugar nucleotidyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 460.0
HFD3_k127_3854038_1 Nucleotidyl transferase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 453.0
HFD3_k127_3854038_2 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000002747 171.0
HFD3_k127_3854038_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000002593 143.0
HFD3_k127_3854038_4 Roadblock/LC7 domain K07131 - - 0.000000000000000000003962 96.0
HFD3_k127_3859195_0 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008969 361.0
HFD3_k127_3859195_1 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 347.0
HFD3_k127_3859195_2 AcrB/AcrD/AcrF family K03296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007757 303.0
HFD3_k127_3892120_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 387.0
HFD3_k127_3892120_1 Sigma-54 interaction domain - - - 0.000000000000000000000000000001251 125.0
HFD3_k127_3892120_2 OST-HTH/LOTUS domain - - - 0.000000000000000000000000000001944 125.0
HFD3_k127_3912865_0 Sodium/calcium exchanger protein K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 319.0
HFD3_k127_3912865_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000003279 236.0
HFD3_k127_3912865_2 HD domain K01139 - 2.7.6.5,3.1.7.2 0.000000000000000000000000000000000000000000005446 171.0
HFD3_k127_3926392_0 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 386.0
HFD3_k127_3926392_1 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.000000000000000000000000000000000000000000000000000000000000399 214.0
HFD3_k127_3926392_3 Recombinase zinc beta ribbon domain - - - 0.0002794 47.0
HFD3_k127_3928025_0 Putative zinc-binding metallo-peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 475.0
HFD3_k127_3928025_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 394.0
HFD3_k127_3928025_2 - - - - 0.00000000000000000003315 96.0
HFD3_k127_3928025_4 Ig domain protein group 2 domain protein - - - 0.0007299 50.0
HFD3_k127_3930086_0 Phospholipase D. Active site motifs. K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 534.0
HFD3_k127_3930086_1 DEAD/H associated K03724 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 491.0
HFD3_k127_3930086_2 Replication initiator protein A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 372.0
HFD3_k127_3930086_3 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000003253 149.0
HFD3_k127_3950002_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.735e-272 846.0
HFD3_k127_3950002_1 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005171 247.0
HFD3_k127_3950002_2 Diacylglycerol kinase catalytic domain (presumed) K07029 - 2.7.1.107 0.0000000000000000000000000000000000000004743 156.0
HFD3_k127_3970288_0 DALR_2 K01883 - 6.1.1.16 7.303e-217 681.0
HFD3_k127_3987181_0 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 388.0
HFD3_k127_3987181_1 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003903 281.0
HFD3_k127_4007147_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 6.407e-296 917.0
HFD3_k127_4007147_1 Protein of unknown function (DUF512) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 479.0
HFD3_k127_4007147_2 MviN-like protein K03980 - - 0.0000000000000000000000000000000000000000000001946 172.0
HFD3_k127_4025755_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000079 347.0
HFD3_k127_4025755_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000824 254.0
HFD3_k127_4025755_2 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.000000000000000000000000000000000000000028 153.0
HFD3_k127_4025755_3 - - - - 0.0000000000000009585 85.0
HFD3_k127_4025755_4 Transcriptional regulatory protein, C terminal K02483,K07667 GO:0008150,GO:0040007 - 0.000000000000002014 86.0
HFD3_k127_4029412_0 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 571.0
HFD3_k127_4029412_1 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 361.0
HFD3_k127_4029412_2 Nodulation protein S (NodS) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 309.0
HFD3_k127_4029412_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000003018 225.0
HFD3_k127_4029412_4 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000001532 186.0
HFD3_k127_4029412_5 - - - - 0.0000000000000000000000000000000000000000000000001687 196.0
HFD3_k127_4057188_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.999e-283 884.0
HFD3_k127_4057188_1 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000001764 94.0
HFD3_k127_4066849_0 lysine biosynthetic process via aminoadipic acid - - - 1.649e-203 645.0
HFD3_k127_4081969_0 Elongation factor SelB winged helix 3 K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 353.0
HFD3_k127_4081969_1 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005977 253.0
HFD3_k127_4081969_2 TonB dependent receptor K02014,K16092 - - 0.000000000000000000000000002898 118.0
HFD3_k127_408210_0 Phenylacetic acid catabolic protein K02609 - 1.14.13.149 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 537.0
HFD3_k127_408210_1 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 303.0
HFD3_k127_408210_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000003158 207.0
HFD3_k127_408210_3 4-amino-4-deoxy-L-arabinose transferase activity K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000008364 185.0
HFD3_k127_408210_4 Phenylacetic acid degradation B K02610 - - 0.000000000000000000000000000000000000000008063 155.0
HFD3_k127_408210_5 Protein of unknown function (DUF3761) - - - 0.0009133 46.0
HFD3_k127_408979_0 Elongation factor G, domain IV K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006381 356.0
HFD3_k127_408979_1 - - - - 0.00000000000000000000000000000000000000000000000008102 184.0
HFD3_k127_408979_2 Outer membrane protein beta-barrel domain - - - 0.00000000000000000000000000003765 121.0
HFD3_k127_408979_3 Phosphoglycerate mutase family - - - 0.00000000000000001497 91.0
HFD3_k127_408979_4 Putative prokaryotic signal transducing protein - - - 0.00000001082 59.0
HFD3_k127_408979_5 Lysozyme inhibitor LprI - - - 0.0007475 51.0
HFD3_k127_4093444_0 permease for cytosine purines, uracil, thiamine, allantoin K03457 - - 9.53e-197 625.0
HFD3_k127_4093444_1 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01431 - 3.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 478.0
HFD3_k127_4093444_2 protein histidine kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 409.0
HFD3_k127_4093444_3 Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 387.0
HFD3_k127_4093444_4 TIGRFAM dihydroorotase, multifunctional complex type K01464 - 3.5.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 357.0
HFD3_k127_4095250_0 ABC transporter transmembrane region - - - 2.05e-238 751.0
HFD3_k127_4095250_1 CarboxypepD_reg-like domain - - - 3.314e-234 764.0
HFD3_k127_4095250_2 Amino acid permease K03294 - - 4.364e-198 627.0
HFD3_k127_4095250_3 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 425.0
HFD3_k127_4095250_4 Cytochrome oxidase assembly protein K02259 - - 0.000000000000000000000000000000000000000000000000000000000000000000001299 251.0
HFD3_k127_4095250_5 siderophore transport K02014 - - 0.0000000000000000000000000000000000000000000000000000000000001609 221.0
HFD3_k127_4095250_6 - - - - 0.00001303 50.0
HFD3_k127_4120083_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 8.806e-196 615.0
HFD3_k127_4120083_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 464.0
HFD3_k127_4120083_2 GIY-YIG type nucleases (URI domain) K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 423.0
HFD3_k127_4120083_3 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 327.0
HFD3_k127_4120083_4 ECF sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002773 276.0
HFD3_k127_4120083_5 Polymer-forming cytoskeletal - - - 0.0000000000000000000003424 104.0
HFD3_k127_4120083_6 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.000000000000000000001456 97.0
HFD3_k127_4120083_7 COG0694 Thioredoxin-like proteins and domains - - - 0.0001812 47.0
HFD3_k127_4128149_0 (Rhomboid) family - - - 0.000000000000000000000000000000000000000000000000000000000000000002096 234.0
HFD3_k127_4128149_1 Tetratricopeptide repeat K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000001422 200.0
HFD3_k127_4128149_2 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000001104 125.0
HFD3_k127_4128149_3 Asp/Glu/Hydantoin racemase K01779 - 5.1.1.13 0.0002185 50.0
HFD3_k127_4163936_0 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008546 329.0
HFD3_k127_4208844_0 UDP binding domain K13015 - 1.1.1.136 6.738e-206 651.0
HFD3_k127_4208844_1 UDP binding domain K00012 - 1.1.1.22 1.924e-199 629.0
HFD3_k127_4208844_2 Outer membrane lipoprotein K05807 - - 0.0000000000000000000000000000000000000000000000000000000000003568 226.0
HFD3_k127_4208844_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000000009997 194.0
HFD3_k127_4208844_4 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000003451 162.0
HFD3_k127_4208844_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.00000000006204 63.0
HFD3_k127_4217298_0 Cys/Met metabolism PLP-dependent enzyme K01761 - 4.4.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 304.0
HFD3_k127_4217298_1 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000001454 166.0
HFD3_k127_422819_0 Domain of unknown function (DUF4118) K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 320.0
HFD3_k127_422819_1 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007197 249.0
HFD3_k127_422819_2 Domain of unknown function (DUF4142) K08995 - - 0.000000000000000000000000000000000000000000000000000000000000000003893 230.0
HFD3_k127_422819_3 amino acid - - - 0.0000000000000000000000000000002052 126.0
HFD3_k127_426019_0 Uncharacterised protein family (UPF0182) K09118 - - 4.647e-238 765.0
HFD3_k127_426019_1 COGs COG4299 conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 490.0
HFD3_k127_4272548_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 432.0
HFD3_k127_4272548_1 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 369.0
HFD3_k127_4272548_2 Cytochrome c oxidase subunit III K02276,K02299 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008955 351.0
HFD3_k127_4272548_3 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.000000000000000000000000000000006669 130.0
HFD3_k127_4272548_4 - - - - 0.000000000009931 68.0
HFD3_k127_4275804_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1423.0
HFD3_k127_4275804_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006169 446.0
HFD3_k127_4275804_2 Prokaryotic dksA/traR C4-type zinc finger - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002892 239.0
HFD3_k127_4275804_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000000000000000000000000004676 228.0
HFD3_k127_4275804_4 DivIVA protein K04074 - - 0.000000000000001388 79.0
HFD3_k127_4275804_5 PFAM CheW domain protein K03408 - - 0.0000000000003169 76.0
HFD3_k127_4281793_0 E1-E2 ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004151 565.0
HFD3_k127_4281793_1 COGs COG2823 periplasmic or secreted lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000003647 226.0
HFD3_k127_4281793_2 Domain of unknown function (DUF4010) - - - 0.000000000000000000003949 97.0
HFD3_k127_4281793_3 Universal stress protein family - - - 0.0000000000000303 83.0
HFD3_k127_4281793_4 Universal stress protein family - - - 0.00001813 56.0
HFD3_k127_4281793_5 Universal stress protein family K06149 - - 0.00009891 54.0
HFD3_k127_435448_0 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 360.0
HFD3_k127_435448_1 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004365 353.0
HFD3_k127_435448_2 Phosphoglucose isomerase K01810 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000001135 218.0
HFD3_k127_4354743_0 Trypsin K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 419.0
HFD3_k127_4354743_1 - - - - 0.00000002959 63.0
HFD3_k127_43689_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 4.795e-214 681.0
HFD3_k127_4399312_0 (ABC) transporter K06147,K06148 - - 9.941e-212 674.0
HFD3_k127_4399312_1 Zinc carboxypeptidase - - - 0.00000000000000000000000000000004028 127.0
HFD3_k127_4399312_2 - - - - 0.000000000000000000000000000002488 130.0
HFD3_k127_4436605_0 Adenylosuccinate lyase C-terminus K01756 - 4.3.2.2 3.957e-201 635.0
HFD3_k127_4436605_1 Trypsin K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 535.0
HFD3_k127_4436605_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005117 409.0
HFD3_k127_4436605_3 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 355.0
HFD3_k127_4436605_4 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000007308 207.0
HFD3_k127_4436605_5 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K08313,K08314 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016832,GO:0044424,GO:0044464,GO:0097023 2.2.1.2 0.00000000000000000000000000000000000000000000726 170.0
HFD3_k127_4444065_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 459.0
HFD3_k127_4444065_1 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 409.0
HFD3_k127_4444065_2 Flavinator of succinate dehydrogenase K09159 - - 0.0000000006915 65.0
HFD3_k127_4446000_0 Carbamoyltransferase C-terminus K00612 - - 9.363e-284 883.0
HFD3_k127_4446000_1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000135 274.0
HFD3_k127_4446000_2 YceI-like domain - - - 0.000000000000000000000000000000000000000000000000001448 188.0
HFD3_k127_4446000_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000002942 178.0
HFD3_k127_4446000_4 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000000000000007935 138.0
HFD3_k127_4446000_5 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000002988 66.0
HFD3_k127_4452971_0 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 438.0
HFD3_k127_4458327_0 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006798 271.0
HFD3_k127_4458327_1 CoA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000002277 207.0
HFD3_k127_4458327_2 Nodulation protein S (NodS) - - - 0.000000000000000000000000000000000003317 146.0
HFD3_k127_4459107_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 478.0
HFD3_k127_4459107_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000411 222.0
HFD3_k127_446698_0 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009541 301.0
HFD3_k127_446698_1 Roadblock/LC7 domain - - - 0.000000000000000000000000000000000000000000000000002547 184.0
HFD3_k127_446698_2 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000004805 133.0
HFD3_k127_446698_3 - - - - 0.0000000000001079 76.0
HFD3_k127_446698_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0003329 49.0
HFD3_k127_4467007_0 Bacterial membrane protein YfhO - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004436 359.0
HFD3_k127_4467007_1 glycosyl transferase group 1 - - - 0.0000000000000000000000000065 114.0
HFD3_k127_4468278_0 polysaccharide deacetylase K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008111 604.0
HFD3_k127_4468278_1 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 413.0
HFD3_k127_4468278_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 330.0
HFD3_k127_4468278_3 N-acetylglucosaminylinositol deacetylase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007593 291.0
HFD3_k127_4468278_4 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000001344 227.0
HFD3_k127_4468278_5 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000003548 197.0
HFD3_k127_4468278_6 Aspartyl protease - - - 0.00000000000000000000000000000001948 142.0
HFD3_k127_4468278_7 - - - - 0.00000000000000001217 91.0
HFD3_k127_4468278_8 DNA-binding transcription factor activity - - - 0.0000000000000001856 93.0
HFD3_k127_4468956_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 544.0
HFD3_k127_4468956_1 MgsA AAA+ ATPase C terminal K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 540.0
HFD3_k127_4468956_2 transporter K07238,K11021,K16267 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005083 253.0
HFD3_k127_4468956_3 CobQ CobB MinD ParA nucleotide binding domain K16554,K16692 - - 0.0000000000000000000000000000000000000000000000000000000000000003173 231.0
HFD3_k127_4468956_4 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000001043 217.0
HFD3_k127_4468956_5 Late embryogenesis abundant protein - - - 0.0000000000000000000000000000000000000000000000000002234 189.0
HFD3_k127_4468956_6 - - - - 0.000000000000000000000000000000000002059 140.0
HFD3_k127_4472397_0 Endoribonuclease that initiates mRNA decay K18682 - - 2.166e-241 755.0
HFD3_k127_4472397_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000002376 153.0
HFD3_k127_4472397_2 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000000005968 95.0
HFD3_k127_4472397_3 - - - - 0.0000000000000001651 82.0
HFD3_k127_4485242_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000001035 268.0
HFD3_k127_4485242_1 Bacterial Ig-like domain - - - 0.0000000000000000000000000000000000000000000000000000000001173 221.0
HFD3_k127_4490045_0 metallopeptidase activity K03568 - - 5.661e-225 708.0
HFD3_k127_4490045_1 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 386.0
HFD3_k127_4490045_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000002565 121.0
HFD3_k127_4504875_0 Aromatic amino acid lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 419.0
HFD3_k127_4504875_1 Domain of unknown function (DUF1835) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000675 256.0
HFD3_k127_4506940_0 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 551.0
HFD3_k127_4506940_1 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000002771 222.0
HFD3_k127_4506940_2 Belongs to the UPF0271 (lamB) family K07160 - - 0.000000000000000007615 97.0
HFD3_k127_4514509_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000761 372.0
HFD3_k127_4514509_1 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.00000000000000000000000000000000000000000000000000001225 205.0
HFD3_k127_454111_0 Major facilitator Superfamily K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 470.0
HFD3_k127_454111_1 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 368.0
HFD3_k127_454111_2 Dipeptidyl peptidase IV (DPP IV) N-terminal region - - - 0.00000000000000000000000000000003483 126.0
HFD3_k127_454111_3 Selenoprotein, putative - - - 0.00000000000002284 77.0
HFD3_k127_4572767_0 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005755 598.0
HFD3_k127_4572767_1 Fructose-bisphosphate aldolase class-II - - - 0.00000000000000000000000000002665 119.0
HFD3_k127_4572767_2 YtxH-like protein - - - 0.0000000000000000000000000003881 117.0
HFD3_k127_4589074_0 MaoC like domain K02618 - 1.2.1.91,3.3.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 514.0
HFD3_k127_4589074_1 Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001384 261.0
HFD3_k127_4589074_2 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000008375 69.0
HFD3_k127_4612509_0 PFAM ABC transporter transmembrane K06147 - - 5.46e-199 627.0
HFD3_k127_4612509_1 extracellular polysaccharide biosynthetic process K13582 - - 0.0000000000000000000000000000000000000000000000000000000000000000001344 243.0
HFD3_k127_4612509_2 Carbohydrate family 9 binding domain-like - - - 0.00000000000000000000000000000000000000000000000000000000006175 209.0
HFD3_k127_4612509_3 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000002412 161.0
HFD3_k127_4612509_4 Putative adhesin - - - 0.00000000000000000000003143 111.0
HFD3_k127_4671664_0 succinyl-diaminopimelate desuccinylase activity K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 446.0
HFD3_k127_4671664_1 Dehydrogenase K07077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000725 333.0
HFD3_k127_4673205_0 Acyl-CoA dehydrogenase, middle domain - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 317.0
HFD3_k127_4673205_1 SURF1 family K14998 - - 0.000000000000000000000000000000000000000000000000000000000007242 214.0
HFD3_k127_4673618_0 2-Nitropropane dioxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006086 604.0
HFD3_k127_4673618_1 Cytochrome C and Quinol oxidase polypeptide I K15862 - 1.9.3.1 0.000000000000000000000000000000000000004092 151.0
HFD3_k127_4673618_2 PFAM blue (type 1) copper domain protein K00368 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.2.1 0.000000000000000000000000000000001014 141.0
HFD3_k127_4673618_3 - K01992,K19341 - - 0.00000000000000000000000285 105.0
HFD3_k127_4673618_4 Cytochrome C and Quinol oxidase polypeptide I - - - 0.000000000009201 65.0
HFD3_k127_47114_0 Protein of unknown function (DUF1624) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000536 362.0
HFD3_k127_47114_1 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001437 255.0
HFD3_k127_4760458_0 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 343.0
HFD3_k127_4760458_1 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.0000000000000000000000000000000000000000000000000000000009648 205.0
HFD3_k127_4760458_2 Methyltransferase domain - - - 0.000000003253 59.0
HFD3_k127_4784475_0 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009434 474.0
HFD3_k127_4784475_1 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 387.0
HFD3_k127_4784475_2 epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007578 298.0
HFD3_k127_4784475_3 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000003921 153.0
HFD3_k127_4784475_4 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000006955 146.0
HFD3_k127_4803106_0 Sodium:solute symporter family - - - 6.239e-226 709.0
HFD3_k127_4803106_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 318.0
HFD3_k127_4803106_2 BadF/BadG/BcrA/BcrD ATPase family K18676 - 2.7.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 293.0
HFD3_k127_4803106_3 Iron-sulphur cluster biosynthesis - - - 0.00000000000000000000000000000000000000000000000000001674 190.0
HFD3_k127_4808546_0 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 352.0
HFD3_k127_4808546_1 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000000000001932 267.0
HFD3_k127_4808546_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001996 245.0
HFD3_k127_4853074_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 9.691e-199 627.0
HFD3_k127_4853074_1 Na H antiporter K03315 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 430.0
HFD3_k127_4853074_2 Cys/Met metabolism PLP-dependent enzyme K01761 - 4.4.1.11 0.000000000000000000000000001051 115.0
HFD3_k127_4854839_0 Amidohydrolase - - - 7.538e-194 611.0
HFD3_k127_4854839_1 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 446.0
HFD3_k127_4854839_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007696 321.0
HFD3_k127_4854839_3 lipolytic protein G-D-S-L family K01179,K01183 - 3.2.1.14,3.2.1.4 0.0000000000000000000000000000000000000000000000000000000004583 211.0
HFD3_k127_4854839_4 PFAM Squalene phytoene synthase K00801 - 2.5.1.21 0.00000000000000000000000000000000000000000000000000005117 192.0
HFD3_k127_4854839_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000004939 170.0
HFD3_k127_4854839_6 Acyl-transferase K00655 - 2.3.1.51 0.0000000000000000000000000000002849 133.0
HFD3_k127_4854839_7 Catalyzes the transfer of an acetyl group from acetyl- CoA to the 6'-amino group of aminoglycoside molecules conferring resistance to antibiotics containing the purpurosamine ring K18816 - 2.3.1.82 0.0008554 47.0
HFD3_k127_488254_0 Pilus formation protein N terminal region K02280 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 349.0
HFD3_k127_488254_1 Flp pilus assembly protein CpaB K02279 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009065 255.0
HFD3_k127_488254_2 aspartic-type endopeptidase activity K02278,K02654 - 3.4.23.43 0.0000000000000000000001563 104.0
HFD3_k127_488254_3 AAA domain K02282 - - 0.000000000001611 76.0
HFD3_k127_488254_4 PFAM Flp Fap pilin component K02651 - - 0.0007442 43.0
HFD3_k127_4913361_0 PFAM ATP dependent DNA ligase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007407 457.0
HFD3_k127_4913361_1 PFAM Phenazine biosynthesis PhzC PhzF protein K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 323.0
HFD3_k127_4913361_2 TonB-dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001572 263.0
HFD3_k127_4913361_3 translation initiation inhibitor, yjgF family K04782 - 4.2.99.21 0.000000000000000000000000000000000000000000000003765 177.0
HFD3_k127_4913361_4 Cold shock protein domain K03704 - - 0.00000000000000000000000000000000006624 136.0
HFD3_k127_4913361_5 - - - - 0.0000000000000005515 83.0
HFD3_k127_4933270_0 cystathionine K01739 - 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 510.0
HFD3_k127_4933270_1 Belongs to the AB hydrolase superfamily. MetX family K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000003977 224.0
HFD3_k127_4933270_2 Homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000003876 195.0
HFD3_k127_4933270_3 membrane - - - 0.0000000000000000000000003732 112.0
HFD3_k127_4933270_4 COG2207 AraC-type DNA-binding domain-containing proteins - - - 0.00000000000000000002636 102.0
HFD3_k127_4933793_0 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006908 332.0
HFD3_k127_4933793_1 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000001883 206.0
HFD3_k127_4933793_2 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000006699 195.0
HFD3_k127_4933793_3 domain, Protein - - - 0.000000000000000004454 94.0
HFD3_k127_4944009_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005055 646.0
HFD3_k127_4944009_1 23S rRNA-intervening sequence protein - - - 0.000000000000001337 81.0
HFD3_k127_4945431_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006142 509.0
HFD3_k127_4945431_1 protein kinase activity - - - 0.000000000000002502 78.0
HFD3_k127_4953112_0 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 471.0
HFD3_k127_4953112_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 445.0
HFD3_k127_4953112_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0000988,GO:0000989,GO:0003674,GO:0003756,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010556,GO:0015035,GO:0015036,GO:0016020,GO:0016032,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0016989,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031326,GO:0032991,GO:0034641,GO:0034645,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0055114,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0140096,GO:0140110,GO:1901360,GO:1901576,GO:1903506,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 342.0
HFD3_k127_4953112_3 Met-10+ like-protein K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 293.0
HFD3_k127_4953112_4 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000000000002613 255.0
HFD3_k127_4953112_5 HIT domain K02503 - - 0.00000000000000000000000000000000000001597 153.0
HFD3_k127_4953112_6 23S rRNA-intervening sequence protein - - - 0.00000000000000004 84.0
HFD3_k127_4954571_0 Sodium:solute symporter family K14392 - - 7.94e-200 629.0
HFD3_k127_4954571_1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 500.0
HFD3_k127_4954571_2 helix_turn _helix lactose operon repressor K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006719 342.0
HFD3_k127_4954571_3 - - - - 0.0000000000000000000000000000000000005867 146.0
HFD3_k127_495649_0 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001918 266.0
HFD3_k127_495649_2 Methyltransferase domain - - - 0.0000000000001978 80.0
HFD3_k127_4957915_0 Peptidase dimerisation domain - - - 7.163e-210 661.0
HFD3_k127_4957915_1 Highly conserved protein containing a thioredoxin domain K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 545.0
HFD3_k127_4957915_2 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000000009097 116.0
HFD3_k127_4957915_3 GDP-mannose mannosyl hydrolase activity - - - 0.000000000000000000000001367 108.0
HFD3_k127_4957915_4 Domain of unknown function (DUF4173) - - - 0.000003874 53.0
HFD3_k127_4982719_0 - - GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008757,GO:0016278,GO:0016740,GO:0016741,GO:0032259 - 1.312e-309 987.0
HFD3_k127_4982719_1 Predicted permease YjgP/YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000574 456.0
HFD3_k127_4982719_2 Predicted permease YjgP/YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 421.0
HFD3_k127_4982719_3 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009701 323.0
HFD3_k127_4982719_4 siderophore transport K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 286.0
HFD3_k127_4982719_5 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006107 269.0
HFD3_k127_4982719_6 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000008307 109.0
HFD3_k127_4986906_0 AMP-binding enzyme C-terminal domain K01907 - 6.2.1.16 6.911e-267 836.0
HFD3_k127_4986906_1 homogentisate 1,2-dioxygenase K00451 - 1.13.11.5 2.458e-226 704.0
HFD3_k127_4986906_2 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005181 570.0
HFD3_k127_4986906_3 - - - - 0.000000007774 56.0
HFD3_k127_4996216_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 1.452e-314 980.0
HFD3_k127_4996216_1 asparaginase activity K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000001451 164.0
HFD3_k127_4996216_2 - - - - 0.0000000007024 63.0
HFD3_k127_5001678_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.759e-208 656.0
HFD3_k127_5001678_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 295.0
HFD3_k127_5001678_2 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000782 142.0
HFD3_k127_5001678_3 Protein of unknown function (DUF494) K03747 - - 0.000000000000000001951 87.0
HFD3_k127_50048_0 5'-nucleotidase, C-terminal domain K01081 - 3.1.3.5 7.851e-280 895.0
HFD3_k127_50048_1 Adenosine/AMP deaminase K01488 - 3.5.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005515 388.0
HFD3_k127_50048_2 Transcriptional regulatory protein, C terminal K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 335.0
HFD3_k127_50048_3 histidine kinase HAMP region domain protein K07636 - 2.7.13.3 0.000000000000000004644 95.0
HFD3_k127_5013680_0 Transport of potassium into the cell K03549 - - 5.757e-252 792.0
HFD3_k127_5013680_1 Transport of potassium into the cell K03549 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 539.0
HFD3_k127_5013680_2 cellular manganese ion homeostasis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000424 377.0
HFD3_k127_5013680_3 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003221 267.0
HFD3_k127_5013680_4 S4 RNA-binding domain K04762 - - 0.000000000000000000000000000000000009127 142.0
HFD3_k127_5013680_5 PDZ domain (Also known as DHR or GLGF) - - - 0.0000000000000000000002256 110.0
HFD3_k127_5039960_0 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 402.0
HFD3_k127_5039960_1 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009166 331.0
HFD3_k127_5039960_2 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000008406 198.0
HFD3_k127_5041484_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 336.0
HFD3_k127_5041484_1 Domain of unknown function (DUF4956) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 299.0
HFD3_k127_5041484_2 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564 2.7.4.1 0.000000000000000000000000000001232 135.0
HFD3_k127_5053327_0 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 496.0
HFD3_k127_5053327_1 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006292 469.0
HFD3_k127_5053327_2 metal ion transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 355.0
HFD3_k127_5053327_3 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000001646 197.0
HFD3_k127_5053327_4 Protein of unknown function (DUF1003) - - - 0.00000000000000000000000000000000000000000000882 169.0
HFD3_k127_5053537_0 Glycosyltransferase K19424 GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016758 - 0.00000000000000000000000000000000005591 148.0
HFD3_k127_5053537_1 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000004035 133.0
HFD3_k127_5053537_2 Vibrio cholerae RfbT protein - - - 0.0000000000000008594 88.0
HFD3_k127_5081128_0 Protein kinase domain K12132 - 2.7.11.1 7.096e-208 672.0
HFD3_k127_5081128_1 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006133 512.0
HFD3_k127_5081128_2 Peptidase family S58 K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 478.0
HFD3_k127_5081128_3 double-stranded DNA 3'-5' exodeoxyribonuclease activity K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005456 276.0
HFD3_k127_5081128_5 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000000000000000006124 165.0
HFD3_k127_5081128_6 PFAM DsrE DsrF-like family K09004 - - 0.000000000000000000000000000000000005253 148.0
HFD3_k127_5081128_7 Sortilin, neurotensin receptor 3, - - - 0.00000000000000000000000000000000001143 139.0
HFD3_k127_5081128_8 Sortilin, neurotensin receptor 3, - - - 0.00000002613 56.0
HFD3_k127_5115966_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 560.0
HFD3_k127_5115966_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000687 547.0
HFD3_k127_5115966_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 353.0
HFD3_k127_5115966_3 Preprotein translocase subunit K03210 - - 0.0000000000000000000000000000005555 129.0
HFD3_k127_5115966_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000007551 122.0
HFD3_k127_5115966_5 Aminotransferase class I and II K10907 - - 0.000000000000000000000000004803 112.0
HFD3_k127_5125489_0 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 587.0
HFD3_k127_5125489_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 316.0
HFD3_k127_5125489_2 - - - - 0.00000000000000000000000000000000000000000000000007533 188.0
HFD3_k127_5125489_3 Diguanylate cyclase, GGDEF domain - - - 0.000000000000000000000000000000401 124.0
HFD3_k127_5146047_0 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 327.0
HFD3_k127_5146047_1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.0000000000000000000000000000000000000009401 154.0
HFD3_k127_5146047_2 Carbohydrate kinase - - - 0.00000000000000000000000002031 110.0
HFD3_k127_5146047_4 chaperone-mediated protein folding - - - 0.0000005753 52.0
HFD3_k127_5156259_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006 - 2.7.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 306.0
HFD3_k127_5156259_1 PFAM Glycosyl transferase, group 1 K08256 - 2.4.1.345 0.000000000000000000000000000000000000000000000000000000000000000000000000000008291 276.0
HFD3_k127_5156259_2 Polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000000000000000000000000003028 185.0
HFD3_k127_5156259_3 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000001047 64.0
HFD3_k127_517268_0 Methionine synthase B12-binding module cap domain protein K00548,K15023 - 2.1.1.13,2.1.1.258 0.0 1291.0
HFD3_k127_517268_1 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005903 480.0
HFD3_k127_5175837_0 Atp-dependent helicase - - - 0.0 1212.0
HFD3_k127_5175837_1 - - - - 0.000000000000000002865 89.0
HFD3_k127_5175837_2 Rdx family K07401 - - 0.000002909 51.0
HFD3_k127_5212495_0 AAA ATPase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004432 481.0
HFD3_k127_5230241_0 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 549.0
HFD3_k127_5230241_1 Uncharacterised conserved protein (DUF2156) - - - 0.0000000000000000000000000000000000000000000000000006241 188.0
HFD3_k127_5257537_0 4 iron, 4 sulfur cluster binding K03737 - 1.2.7.1 0.0 1055.0
HFD3_k127_525989_0 Belongs to the binding-protein-dependent transport system permease family K01989,K05832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003402 256.0
HFD3_k127_525989_1 PFAM ABC transporter related K05833 - - 0.000000000000000000000000000000000000000000000000000000000004865 216.0
HFD3_k127_5269155_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004573 491.0
HFD3_k127_5269155_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 414.0
HFD3_k127_5269155_2 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 311.0
HFD3_k127_5269155_3 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002757 263.0
HFD3_k127_5274441_0 Beta-lactamase K21469 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005415 332.0
HFD3_k127_5274441_1 COG3119 Arylsulfatase A K01137 - 3.1.6.14 0.0000000000000000000000000000000000000004319 153.0
HFD3_k127_5290637_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007319 361.0
HFD3_k127_5290637_1 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000001389 245.0
HFD3_k127_5290637_2 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000000002645 216.0
HFD3_k127_5290637_3 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits - - - 0.00000000000000000000000007054 107.0
HFD3_k127_5296858_0 4Fe-4S binding domain K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 561.0
HFD3_k127_5296858_1 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 334.0
HFD3_k127_5296858_2 FAD binding domain K11472 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 306.0
HFD3_k127_5296858_3 23S rRNA-intervening sequence protein - - - 0.0000000000000005839 82.0
HFD3_k127_5321796_0 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 5.765e-316 979.0
HFD3_k127_5321796_1 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 3.358e-242 758.0
HFD3_k127_5321796_2 PFAM FAD dependent oxidoreductase - - - 4.084e-201 638.0
HFD3_k127_5321796_3 Bacterial protein of unknown function (DUF853) K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 474.0
HFD3_k127_5321796_4 Putative cyclase K07130 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000000000402 203.0
HFD3_k127_5321796_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K15975 - - 0.0000000000000000000000009373 104.0
HFD3_k127_5338560_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 6.925e-256 799.0
HFD3_k127_5338560_1 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 1.422e-245 770.0
HFD3_k127_5338560_2 Fructose-1-6-bisphosphatase, N-terminal domain K03841 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 563.0
HFD3_k127_5338560_3 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 511.0
HFD3_k127_5338560_4 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 466.0
HFD3_k127_5338560_5 Competence protein K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 285.0
HFD3_k127_5338560_6 Regulatory protein, FmdB family - - - 0.00000000000004449 76.0
HFD3_k127_5338560_7 - - - - 0.000001084 56.0
HFD3_k127_5338818_0 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 471.0
HFD3_k127_5338818_1 Protein tyrosine kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.00000000001843 78.0
HFD3_k127_5338818_2 - - - - 0.000001564 59.0
HFD3_k127_5344525_0 Aminoacyl tRNA synthetase class II, N-terminal domain K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000437 459.0
HFD3_k127_5344525_1 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002287 264.0
HFD3_k127_5344525_2 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000000000009232 188.0
HFD3_k127_5344525_3 Ribosomal protein L35 K02916 - - 0.00000000000000005068 83.0
HFD3_k127_5344525_4 B3/4 domain K01890 - 6.1.1.20 0.000000000001191 70.0
HFD3_k127_5344525_5 Metallo-beta-lactamase superfamily - - - 0.0000004165 51.0
HFD3_k127_5369998_0 Fumarase C C-terminus K01744 - 4.3.1.1 1.388e-230 721.0
HFD3_k127_5369998_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009336 481.0
HFD3_k127_5369998_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001118 276.0
HFD3_k127_5369998_3 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003446 240.0
HFD3_k127_5369998_4 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.000000000000000000000000000000000000000000000000000000000005417 212.0
HFD3_k127_5369998_5 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000001 114.0
HFD3_k127_5370854_0 Protein of unknown function (DUF1343) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000963 463.0
HFD3_k127_5370854_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 412.0
HFD3_k127_5384662_0 Transglycosylase K21464 - 2.4.1.129,3.4.16.4 1.483e-205 655.0
HFD3_k127_5384662_1 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 604.0
HFD3_k127_5385114_0 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 3.637e-196 629.0
HFD3_k127_5385114_1 dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes K13356 - 1.2.1.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 350.0
HFD3_k127_5385114_2 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000003738 226.0
HFD3_k127_5385114_3 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00008974 52.0
HFD3_k127_539084_0 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000001903 231.0
HFD3_k127_539084_1 Leishmanolysin - - - 0.000000000000000000000000000000000000000001033 168.0
HFD3_k127_5404589_0 DNA ligase D K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 421.0
HFD3_k127_5404589_1 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000002373 234.0
HFD3_k127_540711_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 468.0
HFD3_k127_540711_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 375.0
HFD3_k127_540711_2 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007597 251.0
HFD3_k127_540711_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000000000001329 175.0
HFD3_k127_540711_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000001596 109.0
HFD3_k127_5430319_0 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 542.0
HFD3_k127_5430319_1 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 423.0
HFD3_k127_5443620_1 NIF3 (NGG1p interacting factor 3) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000852 249.0
HFD3_k127_5443620_2 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000000000000003744 210.0
HFD3_k127_5443620_3 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000001347 149.0
HFD3_k127_5443620_4 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000001672 101.0
HFD3_k127_54552_0 DNA/RNA non-specific endonuclease - - - 3.285e-232 753.0
HFD3_k127_54552_1 Peptidase dimerisation domain - - - 3.498e-197 625.0
HFD3_k127_54552_2 glutamate decarboxylase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 472.0
HFD3_k127_54552_3 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 355.0
HFD3_k127_54552_4 - - - - 0.000000000000000000000000000000000000000000000000000000000009852 222.0
HFD3_k127_54552_5 Protein of Unknown function (DUF2784) - - - 0.00000000000000000000000000000000000000224 151.0
HFD3_k127_54552_6 Predicted membrane protein (DUF2127) - - - 0.000000000000000000000000000000005515 134.0
HFD3_k127_54552_7 - - - - 0.0001577 49.0
HFD3_k127_5477225_0 COG1174 ABC-type proline glycine betaine transport systems, permease component K05845,K05846 - - 0.000000000000000000000000000000000000000000000000000000000000384 227.0
HFD3_k127_5477225_1 ATPases associated with a variety of cellular activities K05847 - - 0.00000000000000000000000000005573 119.0
HFD3_k127_5477225_2 ABC transporter K05846 - - 0.0000000000000001225 93.0
HFD3_k127_5485151_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 327.0
HFD3_k127_5485151_1 - - - - 0.0006137 50.0
HFD3_k127_5498328_0 carbamoyl transferase, NodU family K00612 - - 9.994e-210 667.0
HFD3_k127_5498328_1 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000658 190.0
HFD3_k127_5498328_2 polysaccharide export K01991,K20988 - - 0.000000000002519 76.0
HFD3_k127_5498328_3 Chain length determinant protein - - - 0.0000005484 62.0
HFD3_k127_5502770_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 548.0
HFD3_k127_5502770_1 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 318.0
HFD3_k127_5502770_2 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000009783 91.0
HFD3_k127_5515542_0 5TM C-terminal transporter carbon starvation CstA K06200 - - 7.334e-314 970.0
HFD3_k127_5515542_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 435.0
HFD3_k127_5515542_2 SprT-like family - - - 0.00000000000000000000000000000001689 137.0
HFD3_k127_5527948_0 Carbohydrate family 9 binding domain-like - - - 5e-324 1010.0
HFD3_k127_5527948_1 CarboxypepD_reg-like domain - - - 0.0000000000000000000000000000000000001009 158.0
HFD3_k127_5527948_2 Bacterial regulatory proteins, tetR family - GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000005094 83.0
HFD3_k127_5530703_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 6.436e-244 770.0
HFD3_k127_5530703_1 (ABC) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 413.0
HFD3_k127_5530703_2 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008207 358.0
HFD3_k127_5530703_3 cAMP biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000008893 245.0
HFD3_k127_5530703_4 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000234 220.0
HFD3_k127_5530703_5 Bacterial transcriptional activator domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000001913 201.0
HFD3_k127_5537255_0 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007188 530.0
HFD3_k127_5551876_0 Involved in the tonB-independent uptake of proteins - - - 8.647e-320 1003.0
HFD3_k127_5551876_1 Sporulation related domain - - - 0.00000000000000000000000000000002845 132.0
HFD3_k127_5566524_0 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005776 405.0
HFD3_k127_5566524_1 GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 295.0
HFD3_k127_5566524_2 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000000000000000005081 209.0
HFD3_k127_5566524_3 KR domain - - - 0.000000000000000000000000000000000000000000000000000002758 198.0
HFD3_k127_5566524_4 - - - - 0.0000000000000000000000000000000005767 138.0
HFD3_k127_5570380_0 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001992 267.0
HFD3_k127_5570380_1 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004262 253.0
HFD3_k127_5570380_2 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000009347 227.0
HFD3_k127_5570380_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000003079 122.0
HFD3_k127_5575786_0 Dipeptidyl peptidase IV (DPP IV) N-terminal region - - - 1.774e-232 741.0
HFD3_k127_5575786_1 5TM C-terminal transporter carbon starvation CstA K06200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000079 368.0
HFD3_k127_559820_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 386.0
HFD3_k127_559820_1 HNH nucleases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 327.0
HFD3_k127_559820_2 - - - - 0.0000000000000000000000000000000000000000000000000000000004955 210.0
HFD3_k127_559820_3 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000305 86.0
HFD3_k127_559820_4 - - - - 0.000006884 49.0
HFD3_k127_5602703_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005945 559.0
HFD3_k127_5602703_1 L-asparaginase II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 447.0
HFD3_k127_5602703_2 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 308.0
HFD3_k127_5602703_3 DNA recombination-mediator protein A K04096 - - 0.000000000000000000000000000000000000000000000000000000000001827 218.0
HFD3_k127_5602703_4 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000000000000007496 216.0
HFD3_k127_5610516_0 Outer membrane protein beta-barrel family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005296 531.0
HFD3_k127_5610516_1 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 501.0
HFD3_k127_5610516_2 Pfam:SusD K21572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 462.0
HFD3_k127_5610516_3 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000000001179 203.0
HFD3_k127_5610516_4 - - - - 0.0000000000000000000000000000000000000000000000000002946 200.0
HFD3_k127_5610516_5 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000003387 190.0
HFD3_k127_5610516_6 Glycogen recognition site of AMP-activated protein kinase - - - 0.0000000000000004955 87.0
HFD3_k127_5612991_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009936 262.0
HFD3_k127_5612991_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000002976 224.0
HFD3_k127_5612991_2 Iron-sulfur cluster assembly protein - - - 0.000000000000000000000000000000000000000000392 160.0
HFD3_k127_5614311_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003808 289.0
HFD3_k127_5614311_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000001521 235.0
HFD3_k127_566986_0 Cytochrome c-type biogenesis protein CcmF C-terminal K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 456.0
HFD3_k127_566986_1 Serine aminopeptidase, S33 K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 324.0
HFD3_k127_566986_2 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000000000000000000000000000000000000001048 230.0
HFD3_k127_5689314_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 4.221e-209 666.0
HFD3_k127_5689314_1 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000003395 228.0
HFD3_k127_5689314_2 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000001011 168.0
HFD3_k127_5698955_0 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 502.0
HFD3_k127_5698955_1 Amidinotransferase K01482 - 3.5.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000006107 269.0
HFD3_k127_5698955_10 - - - - 0.0000000034 62.0
HFD3_k127_5698955_11 - - - - 0.000002218 51.0
HFD3_k127_5698955_2 Zinc carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003137 236.0
HFD3_k127_5698955_3 Domain of unknown function (DUF4386) - - - 0.00000000000000000000000000000000000000000000000000000000000004812 221.0
HFD3_k127_5698955_4 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000002462 214.0
HFD3_k127_5698955_5 Protein of unknown function (DUF2975) - - - 0.00000000000000000000000000000000000000000104 162.0
HFD3_k127_5698955_6 Calcium/calmodulin dependent protein kinase II association domain - - - 0.000000000000000000000000000000000000000001224 165.0
HFD3_k127_5698955_7 Transcriptional regulator K07727 - - 0.000000000000000000000000005719 111.0
HFD3_k127_5698955_8 Protein of unknown function (DUF1272) K09984 - - 0.000000000000000000006433 93.0
HFD3_k127_5698955_9 - - - - 0.00000000000000001264 88.0
HFD3_k127_5701334_0 Aldehyde dehydrogenase family K22187 - - 1.156e-272 844.0
HFD3_k127_5701334_1 Bacterial regulatory protein, Fis family - - - 6.263e-212 668.0
HFD3_k127_5701334_2 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 345.0
HFD3_k127_5701334_3 - - - - 0.00000000000000000000000000000000000000000000002553 176.0
HFD3_k127_5705542_0 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 528.0
HFD3_k127_5705542_1 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004408 422.0
HFD3_k127_5705542_2 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000003923 160.0
HFD3_k127_5705542_3 Protein of unknown function, DUF - - - 0.00000000000000000189 89.0
HFD3_k127_571858_0 nitrous-oxide reductase activity K00376,K02275 GO:0000041,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0008150,GO:0015677,GO:0030001,GO:0042597,GO:0044464,GO:0051179,GO:0051234 1.7.2.4,1.9.3.1 3.602e-317 982.0
HFD3_k127_571858_1 HlyD family secretion protein K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003089 285.0
HFD3_k127_571858_2 lipoprotein involved in nitrous oxide reduction K19342 - - 0.0000000000000000000000000000000000000000000000000005914 188.0
HFD3_k127_571858_3 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000006387 190.0
HFD3_k127_571858_4 - - - - 0.0000000000000000000000000001369 121.0
HFD3_k127_5726873_0 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 510.0
HFD3_k127_5726873_1 metal ion transmembrane transporter activity - - - 0.00000000000000000000000000006367 119.0
HFD3_k127_5726873_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000001127 97.0
HFD3_k127_5762270_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008059 327.0
HFD3_k127_5762270_1 NlpC/P60 family - - - 0.00000000000000000000000000000000000000000000000000000000007004 213.0
HFD3_k127_5775871_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009181 555.0
HFD3_k127_5775871_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000004688 256.0
HFD3_k127_5794641_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008832 498.0
HFD3_k127_5794641_1 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 499.0
HFD3_k127_5794641_2 4Fe-4S single cluster domain K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 427.0
HFD3_k127_5794641_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000002687 149.0
HFD3_k127_5801562_0 PFAM Methylated-DNA- protein -cysteine S-methyltransferase DNA binding K10778 - 2.1.1.63 0.00000000000000000000000000000000000003703 154.0
HFD3_k127_5801562_1 copper resistance D domain protein K14166 - - 0.00000000000000000001592 105.0
HFD3_k127_5805797_0 PFAM glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000008576 131.0
HFD3_k127_5805797_1 Glycosyl transferase family 21 - - - 0.00000000000000001485 86.0
HFD3_k127_5889861_0 NapC/NirT cytochrome c family, N-terminal region - - - 0.00000000000000000000038 111.0
HFD3_k127_5894038_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 376.0
HFD3_k127_5894038_1 Putative ATP-binding cassette K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004582 344.0
HFD3_k127_5894038_2 CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000000000000003106 146.0
HFD3_k127_5915319_0 Rhodanese Homology Domain K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 494.0
HFD3_k127_5915319_1 (ABC) transporter K06147,K06148 - - 0.000000000000000000000000000000000000009896 150.0
HFD3_k127_5916891_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1133.0
HFD3_k127_5916891_1 metal ion transmembrane transporter activity - - - 0.00000000602 57.0
HFD3_k127_5922908_0 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 542.0
HFD3_k127_5922908_1 ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004746 520.0
HFD3_k127_5922908_2 SIS domain K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005524 407.0
HFD3_k127_5922908_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 347.0
HFD3_k127_5922908_4 Lipopolysaccharide-assembly, LptC-related - - - 0.000000000000000000000000000000000000000000001226 171.0
HFD3_k127_5922908_5 2-dehydro-3-deoxyphosphooctonate aldolase K01627 - 2.5.1.55 0.0000000000000000000009754 95.0
HFD3_k127_5930932_0 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 407.0
HFD3_k127_5930932_1 Domain of unknown function (DUF4403) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006257 317.0
HFD3_k127_5930932_2 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000002329 198.0
HFD3_k127_5930932_3 metalloendopeptidase activity K03799 - - 0.00000000000000000000000000000000000000000000000000002341 201.0
HFD3_k127_5930932_4 protein secretion by the type I secretion system K11085 - - 0.000000000000000000000000000000000003192 139.0
HFD3_k127_5930932_5 Amino acid permease - - - 0.000000000000000000000000000000113 128.0
HFD3_k127_5948345_0 - - GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008757,GO:0016278,GO:0016740,GO:0016741,GO:0032259 - 2.654e-271 872.0
HFD3_k127_5978423_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 372.0
HFD3_k127_5978423_1 Hsp20/alpha crystallin family K13993 - - 0.000000000000000000000000002994 119.0
HFD3_k127_598302_0 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009365 339.0
HFD3_k127_598302_1 protease with the C-terminal PDZ domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002111 241.0
HFD3_k127_598302_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000002968 107.0
HFD3_k127_6027767_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 1.682e-212 664.0
HFD3_k127_6027767_1 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 313.0
HFD3_k127_6027767_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000004484 129.0
HFD3_k127_6027767_3 Ribosomal protein L33 K02913 - - 0.0000000000000000000000004648 104.0
HFD3_k127_6027767_4 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000000000000000000002043 95.0
HFD3_k127_6035076_0 PFAM Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 376.0
HFD3_k127_6035076_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000005268 71.0
HFD3_k127_603967_0 Tricorn protease C1 domain K08676 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 564.0
HFD3_k127_603967_1 serine-type endopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 378.0
HFD3_k127_603967_2 Helix-turn-helix domain - - - 0.000000001371 68.0
HFD3_k127_6065440_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 477.0
HFD3_k127_6065440_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 402.0
HFD3_k127_6065440_2 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000965 372.0
HFD3_k127_6065440_3 Pyridine nucleotide-disulphide oxidoreductase K21567 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 336.0
HFD3_k127_6065440_4 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007447 305.0
HFD3_k127_6065440_5 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000004129 224.0
HFD3_k127_6065440_6 3D domain protein - - - 0.00000000000000000000000000000000001778 143.0
HFD3_k127_6072639_0 oxidoreductase activity K00274 - 1.4.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000003492 277.0
HFD3_k127_6072639_1 protein kinase activity - - - 0.00000000000000000000001329 108.0
HFD3_k127_6072639_2 acetyltransferase - GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 - 0.000001462 60.0
HFD3_k127_6076941_0 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309,K11102,K11103 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008775 494.0
HFD3_k127_6076941_1 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002616 428.0
HFD3_k127_6076941_2 glycosyl hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003651 280.0
HFD3_k127_6076941_3 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004364 254.0
HFD3_k127_6076941_4 NmrA-like family K19267 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000001231 253.0
HFD3_k127_6076941_5 - - - - 0.000000000000000000000000000000000000000000000005685 179.0
HFD3_k127_6076941_7 - - - - 0.000000000000000000001623 102.0
HFD3_k127_6076941_8 Dynamin family - - - 0.00000000000000000005849 93.0
HFD3_k127_6076941_9 Ig domain protein group 1 domain protein - - - 0.00009613 48.0
HFD3_k127_6080316_0 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000005543 164.0
HFD3_k127_609223_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1366.0
HFD3_k127_609223_1 cyclic-guanylate-specific phosphodiesterase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008781 566.0
HFD3_k127_6143495_0 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 367.0
HFD3_k127_6143495_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006434 346.0
HFD3_k127_6143495_2 ABC transporter K01990 - - 0.000000000612 63.0
HFD3_k127_6165754_0 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003879 341.0
HFD3_k127_6165754_1 Belongs to the peptidase S51 family K13282 - 3.4.15.6 0.0000000000000000000000000000000000000005726 158.0
HFD3_k127_6179458_0 SurA N-terminal domain K03770 - 5.2.1.8 1.42e-209 667.0
HFD3_k127_6179458_1 Polyprenyl synthetase K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005197 385.0
HFD3_k127_6179458_2 Amidohydrolase family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 346.0
HFD3_k127_6179458_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001261 292.0
HFD3_k127_6179458_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000001062 181.0
HFD3_k127_6179458_5 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000005353 158.0
HFD3_k127_6179458_6 Domain of unknown function (DUF4321) - - - 0.000000000000000000000000000000000009444 143.0
HFD3_k127_6179458_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000001353 91.0
HFD3_k127_6197691_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 424.0
HFD3_k127_6197691_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 332.0
HFD3_k127_6197691_2 HisG, C-terminal domain K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000568 265.0
HFD3_k127_6197691_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000002869 233.0
HFD3_k127_6197691_4 Histidine biosynthesis protein K01814 - 5.3.1.16 0.000000000001189 70.0
HFD3_k127_6220436_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 1.145e-233 729.0
HFD3_k127_6220436_1 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 588.0
HFD3_k127_6220436_2 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 549.0
HFD3_k127_6220436_3 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008198 449.0
HFD3_k127_6220436_4 Conserved TM helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 339.0
HFD3_k127_6220436_5 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004287 313.0
HFD3_k127_6220436_6 - - - - 0.000000000000000000000000002506 112.0
HFD3_k127_6220436_7 Protein of unknown function (DUF1501) - - - 0.000001026 50.0
HFD3_k127_6220436_8 Acetyltransferase (GNAT) family - - - 0.000004721 57.0
HFD3_k127_6252732_0 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 411.0
HFD3_k127_6252732_1 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000366 264.0
HFD3_k127_6252732_2 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000003599 236.0
HFD3_k127_6252732_3 polysaccharide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000001358 216.0
HFD3_k127_6252732_4 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000003296 73.0
HFD3_k127_6258055_0 Pyridine nucleotide-disulphide oxidoreductase - - - 7.898e-211 667.0
HFD3_k127_6258055_1 GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008619 311.0
HFD3_k127_6258055_2 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000032 268.0
HFD3_k127_6258055_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000005069 223.0
HFD3_k127_6258055_4 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000131 187.0
HFD3_k127_6260455_0 BlaR1 peptidase M56 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008349 440.0
HFD3_k127_6260455_1 glyoxalase bleomycin resistance protein dioxygenase K15975 - - 0.000000000000000000000000000000000000000000000000000000000000001029 221.0
HFD3_k127_6260455_2 Penicillinase repressor - - - 0.0000000000000000000000000000000000000000009653 160.0
HFD3_k127_6309952_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001165 263.0
HFD3_k127_6310547_0 Carboxypeptidase regulatory-like domain - - - 0.0 1125.0
HFD3_k127_6310547_1 - - - - 0.0000000000000000000000000000000000000000000000007206 183.0
HFD3_k127_6319594_0 membrane organization - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000517 511.0
HFD3_k127_6319594_1 Glycosyl hydrolase-like 10 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 446.0
HFD3_k127_6319594_2 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000009634 225.0
HFD3_k127_6319594_3 - - - - 0.00000000000000000000006537 111.0
HFD3_k127_6319600_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1313.0
HFD3_k127_6319600_1 EamA-like transporter family - - - 0.000000000000000000000000000000000002179 143.0
HFD3_k127_6338224_0 FecCD transport family K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007722 356.0
HFD3_k127_6338224_1 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007863 292.0
HFD3_k127_6338224_2 ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002079 284.0
HFD3_k127_6338224_3 Cytochrome c - - - 0.0000000000000000000002158 100.0
HFD3_k127_6348574_0 TonB-dependent receptor - - - 1.008e-197 646.0
HFD3_k127_6348574_1 Transcriptional regulator K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 335.0
HFD3_k127_6348574_2 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003131 312.0
HFD3_k127_6359396_0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 353.0
HFD3_k127_6359396_1 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000000000000000000000000005545 230.0
HFD3_k127_6359396_2 Ham1 family K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000008078 228.0
HFD3_k127_6359396_3 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000005026 124.0
HFD3_k127_6371785_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007226 486.0
HFD3_k127_6371785_1 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 415.0
HFD3_k127_6371785_2 ankyrin repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009967 394.0
HFD3_k127_6371785_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003381 351.0
HFD3_k127_6371785_4 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008271 311.0
HFD3_k127_6371785_5 B domain of TMEM189, localisation domain K20656 - - 0.0000000000000000000000000000000000000000000000005266 183.0
HFD3_k127_6373608_0 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 321.0
HFD3_k127_6373608_1 protein kinase activity - - - 0.0000000000000000008822 91.0
HFD3_k127_6392052_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 471.0
HFD3_k127_6392052_1 Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA. It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base. The complementary strand guanine functions in substrate recognition. Required for DNA damage lesion repair in stationary-phase cells K03649 - 3.2.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000004378 244.0
HFD3_k127_6392052_2 Protein of unknown function (DUF2911) - - - 0.0000000000000000000000000000000000000000000000000000001126 201.0
HFD3_k127_6392052_3 enzyme related to lactoylglutathione lyase K06996 - - 0.0000000000000000000000000000000000000000000002475 179.0
HFD3_k127_6392052_4 COG2346, Truncated hemoglobins K06886 - - 0.0000000000000000000000000000000000000000002402 163.0
HFD3_k127_6392052_5 glyoxalase III activity - - - 0.00000000000000002737 81.0
HFD3_k127_6397073_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 5.636e-273 847.0
HFD3_k127_6397073_1 Zn peptidase - - - 0.000000000000000000000000000000000000000000000004565 178.0
HFD3_k127_6397073_2 Protein of unknown function (DUF445) - - - 0.00000001455 66.0
HFD3_k127_6420017_0 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000001651 255.0
HFD3_k127_6420017_1 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000003511 220.0
HFD3_k127_6420017_2 - - - - 0.00000000000000000000000000000000000000000000000000005438 197.0
HFD3_k127_6420017_3 - - - - 0.00000000000000000000000000000000000000000001243 173.0
HFD3_k127_6420017_4 - - - - 0.0000000000000000000000006092 115.0
HFD3_k127_6420017_5 sister chromatid segregation - - - 0.0000000000001833 76.0
HFD3_k127_6430259_0 Pyridoxal-dependent decarboxylase conserved domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 566.0
HFD3_k127_6430259_1 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000395 285.0
HFD3_k127_6430259_2 Sortilin, neurotensin receptor 3, - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003683 261.0
HFD3_k127_6430259_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000003293 164.0
HFD3_k127_6431377_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 2.976e-231 737.0
HFD3_k127_6431377_1 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003099 246.0
HFD3_k127_647489_0 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 348.0
HFD3_k127_647489_1 Fe-S cluster K03616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007499 318.0
HFD3_k127_647489_2 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000004361 103.0
HFD3_k127_647489_3 4 iron, 4 sulfur cluster binding K03737 - 1.2.7.1 0.00000000000000698 75.0
HFD3_k127_6489030_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005303 493.0
HFD3_k127_6489030_1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K02564 - 3.5.99.6 0.00000000000000000000000001805 111.0
HFD3_k127_6489030_2 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000007109 91.0
HFD3_k127_6490516_0 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 6.062e-235 735.0
HFD3_k127_6490516_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000008089 228.0
HFD3_k127_6490516_2 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000001859 224.0
HFD3_k127_6490516_3 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000001131 198.0
HFD3_k127_6490516_4 HAD-hyrolase-like K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000003299 173.0
HFD3_k127_6492737_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009415 462.0
HFD3_k127_6492737_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 338.0
HFD3_k127_6492737_2 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003682 254.0
HFD3_k127_6492737_3 - - - - 0.000000000000000000000000002595 113.0
HFD3_k127_6492737_4 Bacterial protein of unknown function (DUF885) - - - 0.000000000000002515 83.0
HFD3_k127_6495677_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 2.794e-213 668.0
HFD3_k127_6495677_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000241 282.0
HFD3_k127_6495677_2 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000003543 268.0
HFD3_k127_6495677_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000006545 247.0
HFD3_k127_6502002_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007656 538.0
HFD3_k127_6502002_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 313.0
HFD3_k127_6502002_2 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 306.0
HFD3_k127_6502002_3 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000000000000000253 148.0
HFD3_k127_6505666_0 3' exoribonuclease, RNase T-like K03656,K03657 - 3.6.4.12 0.000000000000000000000000000000002281 145.0
HFD3_k127_6524703_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.555e-226 714.0
HFD3_k127_6524703_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000001433 112.0
HFD3_k127_6524703_2 4-vinyl reductase, 4VR - - - 0.00000000000000000001428 98.0
HFD3_k127_6548419_0 Belongs to the universal stress protein A family - - - 0.00000000000000000000000003006 119.0
HFD3_k127_6548419_1 translation release factor activity - - - 0.0000000000008405 80.0
HFD3_k127_6548419_2 HicB family - - - 0.0000004301 54.0
HFD3_k127_6548419_3 Sulfite exporter TauE/SafE K07090 - - 0.0001373 48.0
HFD3_k127_6573589_0 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006077 305.0
HFD3_k127_6573589_1 MerR, DNA binding K13639 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002491 246.0
HFD3_k127_6573589_2 glyoxalase III activity - - - 0.000000000000000000000000000000000000000008072 163.0
HFD3_k127_6573589_3 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000001188 64.0
HFD3_k127_6573589_4 Sodium:dicarboxylate symporter family - - - 0.00000006963 55.0
HFD3_k127_6582948_0 Cytochrome c-type biogenesis protein K02198 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006086 588.0
HFD3_k127_6582948_1 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 475.0
HFD3_k127_6582948_2 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003649 287.0
HFD3_k127_6582948_3 Redoxin K02199 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000000000000000000000000417 135.0
HFD3_k127_6582948_4 - - - - 0.00000000000000000000000000004126 125.0
HFD3_k127_6582948_5 subunit of a heme lyase K02200 - - 0.00000000000000000000003456 107.0
HFD3_k127_6605270_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008929 321.0
HFD3_k127_6605813_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 376.0
HFD3_k127_6609131_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 599.0
HFD3_k127_6609131_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001925 249.0
HFD3_k127_6611643_0 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001666 244.0
HFD3_k127_6611643_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000003801 228.0
HFD3_k127_6611643_2 dihydrofolate reductase activity K00287 - 1.5.1.3 0.000000000000000000000000000000007199 129.0
HFD3_k127_6611643_3 Acetyltransferase (GNAT) domain - GO:0003674,GO:0003824,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747 - 0.00001965 48.0
HFD3_k127_6613748_0 Outer membrane protein beta-barrel family - - - 0.000000000000000000000000000000000000000000000000000001885 204.0
HFD3_k127_6624657_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 358.0
HFD3_k127_6624657_1 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 319.0
HFD3_k127_6624657_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006886 283.0
HFD3_k127_6624657_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000002316 115.0
HFD3_k127_6626518_0 Amino acid kinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 583.0
HFD3_k127_6626518_1 Semialdehyde dehydrogenase, NAD binding domain K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004958 421.0
HFD3_k127_6628568_0 xanthine dehydrogenase activity K13479 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 377.0
HFD3_k127_6628568_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01466 GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 372.0
HFD3_k127_6628568_2 2 iron, 2 sulfur cluster binding K03518,K07302,K13483 - 1.2.5.3,1.3.99.16 0.0000000000000000000000000000000000000215 144.0
HFD3_k127_6652569_0 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 400.0
HFD3_k127_6652569_1 alcohol dehydrogenase K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 402.0
HFD3_k127_6652569_2 Belongs to the UPF0178 family K09768 - - 0.0000000000000000000000000000000000000000000000102 175.0
HFD3_k127_6652569_3 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000882 169.0
HFD3_k127_6652569_5 - - - - 0.0000000000000000000000000000001617 131.0
HFD3_k127_6652569_6 - - - - 0.000000000000000000000000000002156 123.0
HFD3_k127_666427_0 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004828 565.0
HFD3_k127_666427_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 466.0
HFD3_k127_666427_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 364.0
HFD3_k127_666427_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000931 74.0
HFD3_k127_6669039_0 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K16363 - 3.5.1.108,4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005705 580.0
HFD3_k127_6669039_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008811 409.0
HFD3_k127_6669039_2 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 383.0
HFD3_k127_6669039_3 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009528 354.0
HFD3_k127_6669039_4 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000005233 115.0
HFD3_k127_6671738_0 Homoserine dehydrogenase, NAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005449 430.0
HFD3_k127_6671738_1 Stage II sporulation protein K06381 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000452 355.0
HFD3_k127_6671738_2 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000002513 183.0
HFD3_k127_6671738_3 Domain of unknown function (DUF4105) - - - 0.00000000000000000008979 93.0
HFD3_k127_6674773_0 Serine/Threonine protein kinases, catalytic domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006409 476.0
HFD3_k127_6674773_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 423.0
HFD3_k127_6676985_0 ABC transporter transmembrane region K18890 - - 5.498e-227 719.0
HFD3_k127_6676985_1 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005881 287.0
HFD3_k127_6715770_0 beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003812 455.0
HFD3_k127_6715770_1 Belongs to the UPF0173 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001111 253.0
HFD3_k127_6715770_2 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000009184 245.0
HFD3_k127_6715770_3 Uncharacterised conserved protein (DUF2156) - - - 0.000000000000000000000000000000000000000000000000002274 187.0
HFD3_k127_6715770_4 helix_turn_helix, mercury resistance K22491 - - 0.000000000000000000000000000000000000000000001985 177.0
HFD3_k127_6715770_5 Beta-Ig-H3 fasciclin - - - 0.000000000000000000000000000000001052 137.0
HFD3_k127_6715770_6 Protein of unknown function (DUF4230) - - - 0.000000000009817 73.0
HFD3_k127_6719461_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 5.347e-297 935.0
HFD3_k127_6719461_1 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000008554 242.0
HFD3_k127_6719461_2 COGs COG2380 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000373 233.0
HFD3_k127_6719461_3 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000000000000000004808 139.0
HFD3_k127_6774391_0 NADH:flavin oxidoreductase / NADH oxidase family K09461 - 1.14.13.40 0.0 1159.0
HFD3_k127_6774391_1 AMP-binding enzyme C-terminal domain K08295 - 6.2.1.32 2.058e-255 797.0
HFD3_k127_6774391_10 Protein of unknown function (DUF3037) - - - 0.000000000000000000000000000001305 125.0
HFD3_k127_6774391_2 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 490.0
HFD3_k127_6774391_3 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 471.0
HFD3_k127_6774391_4 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 386.0
HFD3_k127_6774391_5 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007922 303.0
HFD3_k127_6774391_6 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003422 308.0
HFD3_k127_6774391_7 cellular response to dsDNA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001299 265.0
HFD3_k127_6774391_8 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000002795 181.0
HFD3_k127_6774391_9 methyltransferase activity - - - 0.000000000000000000000000000000000005575 145.0
HFD3_k127_6779856_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008679 440.0
HFD3_k127_6779856_1 Peptidase family M49 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004788 243.0
HFD3_k127_6779856_2 haloacid dehalogenase-like hydrolase K01079 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000009107 199.0
HFD3_k127_6795314_0 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000006472 233.0
HFD3_k127_6797012_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 505.0
HFD3_k127_6797012_1 cytochrome c oxidase subunit I K02274 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007546 350.0
HFD3_k127_6803562_0 DNA restriction-modification system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 408.0
HFD3_k127_6803562_1 Mechanosensitive ion channel - - - 0.0000003045 59.0
HFD3_k127_6813227_0 LD-carboxypeptidase K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 318.0
HFD3_k127_6813227_1 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 290.0
HFD3_k127_6813227_2 alpha beta K06889 - - 0.00000000000000000000000000000000000000000000002138 181.0
HFD3_k127_6813227_3 Rhodanese Homology Domain - - - 0.000000000000000000000000000000005533 131.0
HFD3_k127_6813227_4 Glycosyl transferase family 21 K00721 - 2.4.1.83 0.00000000000000000006856 91.0
HFD3_k127_681415_0 Bacterial periplasmic substrate-binding proteins K02029,K02030 - - 1.062e-207 656.0
HFD3_k127_681415_1 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 364.0
HFD3_k127_681415_2 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002592 271.0
HFD3_k127_681415_3 AAA domain, putative AbiEii toxin, Type IV TA system K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000001978 252.0
HFD3_k127_681415_4 Pyridoxal-phosphate dependent enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000003322 235.0
HFD3_k127_681415_5 Clp amino terminal domain, pathogenicity island component K03696 - - 0.0000000000000000000000000000000000000000000000006788 188.0
HFD3_k127_681415_6 DinB family - - - 0.000000000000000000017 104.0
HFD3_k127_681415_7 COG4846 Membrane protein involved in cytochrome C biogenesis - - - 0.00000000000002974 80.0
HFD3_k127_68177_0 PFAM Dynamin family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003023 275.0
HFD3_k127_68177_1 Protein of unknown function (DUF1572) - - - 0.000000000000000001378 89.0
HFD3_k127_6830081_0 Sortilin, neurotensin receptor 3, - - - 1.516e-292 932.0
HFD3_k127_6830081_1 cytochrome p450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 548.0
HFD3_k127_6830081_2 Putative serine dehydratase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008939 400.0
HFD3_k127_6830081_3 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000006287 243.0
HFD3_k127_6830081_4 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000003233 203.0
HFD3_k127_6830081_5 IMP dehydrogenase activity - GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0030312,GO:0035821,GO:0036293,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052564,GO:0052572,GO:0070482,GO:0071944,GO:0075136 - 0.000000000000000000000000000001065 127.0
HFD3_k127_6830081_6 Domain of unknown function (DUF4142) K08995 - - 0.0000000000000000000000000002213 124.0
HFD3_k127_6830081_7 Aldehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000004005 51.0
HFD3_k127_6830849_0 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007002 293.0
HFD3_k127_6830849_1 TPR repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000001124 187.0
HFD3_k127_6830849_2 Wd-40 repeat - - - 0.000000000000000000000000000002049 128.0
HFD3_k127_6839981_0 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006476 303.0
HFD3_k127_6839981_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000001769 228.0
HFD3_k127_6839981_2 ECF sigma factor - - - 0.00000000000000000000000000000000000000000195 162.0
HFD3_k127_6839981_3 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000000000000000000002289 117.0
HFD3_k127_6839981_4 ribosomal protein - - - 0.00000000000007114 78.0
HFD3_k127_6839981_5 cAMP biosynthetic process - - - 0.0000000000001621 82.0
HFD3_k127_685680_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 4.835e-308 952.0
HFD3_k127_685680_1 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840 - 5.4.2.8 4.383e-205 646.0
HFD3_k127_685680_2 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000003447 142.0
HFD3_k127_6871503_0 Elongation factor G, domain IV K02355 - - 2.195e-213 671.0
HFD3_k127_6871503_1 lactoylglutathione lyase activity K01759 - 4.4.1.5 0.000000000000000000000000000000000000001178 152.0
HFD3_k127_6871503_2 - - - - 0.0000000000000000000000000000006502 126.0
HFD3_k127_6871503_3 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000009373 122.0
HFD3_k127_6871503_4 Protein of Unknown function (DUF2784) - - - 0.0000000000000000002976 94.0
HFD3_k127_6884218_0 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 571.0
HFD3_k127_6884218_1 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000899 189.0
HFD3_k127_6884218_2 Tfp pilus assembly protein FimT - - - 0.000000000000001719 81.0
HFD3_k127_6884218_3 - - - - 0.0007442 43.0
HFD3_k127_6888056_0 membrane organization - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000107 292.0
HFD3_k127_6901896_0 Participates in the control of copper homeostasis K06201 - - 0.000000000000000000000000000000000000000000000000000002699 194.0
HFD3_k127_6901896_1 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000001848 183.0
HFD3_k127_6901896_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000009313 134.0
HFD3_k127_6901896_3 amidohydrolase - - - 0.0000000000000000000000000000001374 126.0
HFD3_k127_6901896_5 - - - - 0.0001627 51.0
HFD3_k127_6940533_0 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 386.0
HFD3_k127_6940533_1 TPR repeat - - - 0.00001064 57.0
HFD3_k127_6954211_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000625 467.0
HFD3_k127_6954211_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 443.0
HFD3_k127_6954211_2 response regulator K02477 - - 0.0000000000000000000000000000000000000000000000000000000003175 212.0
HFD3_k127_6954211_3 Histidine kinase K08082 - 2.7.13.3 0.000000000000000000000000000000000000000000000000007189 195.0
HFD3_k127_6954211_4 sirohydrochlorin cobaltochelatase activity K03794 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009058,GO:0009507,GO:0009536,GO:0009987,GO:0016829,GO:0018130,GO:0019354,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046156,GO:0046483,GO:0048037,GO:0050896,GO:0051186,GO:0051188,GO:0051266,GO:0051536,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.4 0.0000000000000000000000000000009457 127.0
HFD3_k127_6954211_5 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000003797 117.0
HFD3_k127_6954211_6 Putative esterase K07017 - - 0.00000000000000000001667 106.0
HFD3_k127_6965221_0 Sortilin, neurotensin receptor 3, - - - 0.0 1038.0
HFD3_k127_6965221_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.515e-301 929.0
HFD3_k127_6965221_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000008341 234.0
HFD3_k127_6965221_3 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000003077 214.0
HFD3_k127_6965221_4 ErfK ybiS ycfS ynhG family protein K19234 - - 0.00000000000000000000000000000000000000000000000000000000006532 210.0
HFD3_k127_6965221_5 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000001238 213.0
HFD3_k127_6965221_6 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000000000006031 159.0
HFD3_k127_6965221_7 - - - - 0.0000000000000000000000000003741 122.0
HFD3_k127_6965221_8 Protein of unknown function (DUF1572) - - - 0.0000000000000000000000003769 114.0
HFD3_k127_6970193_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 7.079e-264 820.0
HFD3_k127_6970193_1 lipopolysaccharide-transporting ATPase activity K06861 - - 0.000000000000000000001554 98.0
HFD3_k127_6976747_0 lysine biosynthetic process via aminoadipic acid - - - 2.342e-289 900.0
HFD3_k127_6976747_1 Domain of Unknown Function (DUF1259) - - - 0.00000000000000000000001626 104.0
HFD3_k127_6994272_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 495.0
HFD3_k127_6994272_1 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001435 276.0
HFD3_k127_7001278_0 MBOAT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008373 557.0
HFD3_k127_7001278_1 - - - - 0.000000000000000000000000000000000000002132 160.0
HFD3_k127_7001278_2 - - - - 0.000000000000000000000000000000000000009001 160.0
HFD3_k127_7001278_3 Helix-turn-helix domain - - - 0.0000000009831 69.0
HFD3_k127_7010124_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004107 462.0
HFD3_k127_7010124_1 RadC-like JAB domain K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 320.0
HFD3_k127_7031593_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006804 606.0
HFD3_k127_7031593_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006901 373.0
HFD3_k127_7031593_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004396 258.0
HFD3_k127_7031593_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000001511 255.0
HFD3_k127_7038616_0 peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 376.0
HFD3_k127_7038616_1 Domain of unknown function (DUF4386) - - - 0.000000000000000000000000000000000000000000000000000000000000000001431 235.0
HFD3_k127_7038616_2 Sortilin, neurotensin receptor 3, - - - 0.0000000000000000000000000000000000000000000000000000000000001087 221.0
HFD3_k127_7038616_3 Protein of unknown function (DUF998) - - - 0.00000000000000000000000000000000000000000000004728 178.0
HFD3_k127_7038616_4 Belongs to the DapA family K01714 - 4.3.3.7 0.000000000000000000000000000000000000000004478 157.0
HFD3_k127_7038616_5 - - - - 0.00000000000000000000000001205 117.0
HFD3_k127_7043917_0 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 403.0
HFD3_k127_7043917_1 Diacylglycerol kinase catalytic domain (presumed) K07029 - 2.7.1.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002032 295.0
HFD3_k127_7050658_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007496 356.0
HFD3_k127_7050658_1 Domain of unknown function (DUF4105) - - - 0.0000000000000000000000000000000000000000000000000000000000000002633 231.0
HFD3_k127_7060283_0 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 330.0
HFD3_k127_7060283_1 Belongs to the bacterial solute-binding protein 9 family - - - 0.000000000000000000001964 99.0
HFD3_k127_7060283_2 - - - - 0.000000000000000003565 94.0
HFD3_k127_7061171_0 Domain of unknown function (DUF5118) - - - 3.348e-267 846.0
HFD3_k127_7061171_1 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 521.0
HFD3_k127_7061171_10 TonB-dependent receptor - - - 0.000000000000000000000001699 115.0
HFD3_k127_7061171_11 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000005831 106.0
HFD3_k127_7061171_2 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008264 326.0
HFD3_k127_7061171_3 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 318.0
HFD3_k127_7061171_4 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000001286 240.0
HFD3_k127_7061171_5 2'-5' RNA ligase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000001037 223.0
HFD3_k127_7061171_6 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000001383 224.0
HFD3_k127_7061171_7 phosphatidate phosphatase activity K00901,K01096,K19302 - 2.7.1.107,3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.000000000000000000000000000000000000000000000004759 182.0
HFD3_k127_7061171_8 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000009788 148.0
HFD3_k127_7061171_9 Vault protein inter-alpha-trypsin domain K07114 - - 0.0000000000000000000000000000000000000155 157.0
HFD3_k127_7075199_0 Hsp70 protein K03569 - - 3.716e-198 620.0
HFD3_k127_7075199_1 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007837 606.0
HFD3_k127_7075199_2 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000006065 222.0
HFD3_k127_7075199_3 rod shape-determining protein MreC K03570 - - 0.00000000000000000000000000000000000000008106 159.0
HFD3_k127_7086497_0 Polysaccharide biosynthesis/export protein K01991 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 419.0
HFD3_k127_7086497_1 Capsule assembly protein Wzi - - - 0.000000000000000000000008257 117.0
HFD3_k127_7086497_2 Predicted periplasmic lipoprotein (DUF2279) - - - 0.000000000000001512 82.0
HFD3_k127_7092426_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 2.29e-261 817.0
HFD3_k127_7092426_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 494.0
HFD3_k127_7092426_10 PTS system fructose IIA component K02744 - - 0.00000000000000000000000000004068 121.0
HFD3_k127_7092426_11 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000009109 93.0
HFD3_k127_7092426_2 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009884 435.0
HFD3_k127_7092426_3 PTS system mannose/fructose/sorbose family IID component K02796 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 314.0
HFD3_k127_7092426_4 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000000000004117 243.0
HFD3_k127_7092426_5 PTS system sorbose subfamily IIB component K19507 - - 0.0000000000000000000000000000000000000000000000000000000000006191 215.0
HFD3_k127_7092426_6 PTS system sorbose-specific iic component K02795 - - 0.000000000000000000000000000000000000000000000000000000001454 207.0
HFD3_k127_7092426_7 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000000000000000002119 184.0
HFD3_k127_7092426_8 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000001069 130.0
HFD3_k127_7092426_9 PTS HPr component phosphorylation site K11189 - - 0.000000000000000000000000000004059 122.0
HFD3_k127_7098610_0 ABC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 438.0
HFD3_k127_7098610_1 Histidine biosynthesis bifunctional protein HisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000002819 261.0
HFD3_k127_7102441_0 Protein export membrane protein - - - 0.0 1559.0
HFD3_k127_7102441_1 Protein of unknown function (DUF2892) - - - 0.000000000000000000000002957 103.0
HFD3_k127_7102441_2 DNA-binding transcription factor activity K03892 - - 0.000000000000001047 80.0
HFD3_k127_7105907_0 Transglycosylase K21464 - 2.4.1.129,3.4.16.4 7.133e-269 844.0
HFD3_k127_7105907_1 NAD synthase K01916 - 6.3.1.5 9.049e-252 793.0
HFD3_k127_7105907_3 - - - - 0.00000000000001548 82.0
HFD3_k127_7116199_0 His Kinase A (phosphoacceptor) domain - - - 0.0 1180.0
HFD3_k127_7116199_1 RecQ zinc-binding K03654 - 3.6.4.12 2.27e-231 724.0
HFD3_k127_7116199_2 Putative RNA methylase family UPF0020 K07444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 321.0
HFD3_k127_7116199_3 transcriptional regulator K09017 - - 0.000000000000000000000000000000000000000000000000000000000000259 218.0
HFD3_k127_7116199_4 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000004127 174.0
HFD3_k127_7116199_5 OsmC-like protein K04063 - - 0.0000000000000000000000000000000000004575 144.0
HFD3_k127_7128228_0 ABC transporter K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 623.0
HFD3_k127_7128228_1 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 505.0
HFD3_k127_7128228_2 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003658 443.0
HFD3_k127_7128228_3 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004707 384.0
HFD3_k127_7128228_4 ArsC family - - - 0.00000000000000000000000000000000002383 136.0
HFD3_k127_7131320_0 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008777 349.0
HFD3_k127_7131320_1 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 355.0
HFD3_k127_7131320_2 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000000000000008126 218.0
HFD3_k127_7131320_3 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000000000000000000000000004056 216.0
HFD3_k127_7131320_4 Intracellular proteinase inhibitor - - - 0.0000000000000000000000000002226 120.0
HFD3_k127_7131320_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000003029 96.0
HFD3_k127_7131320_6 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.00000000000003936 75.0
HFD3_k127_7131320_7 - - - - 0.000002418 57.0
HFD3_k127_7131528_0 Nucleoside H+ symporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 490.0
HFD3_k127_7131528_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 407.0
HFD3_k127_7131528_2 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000002486 230.0
HFD3_k127_7133672_0 Belongs to the amidase family K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 539.0
HFD3_k127_7133672_1 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 319.0
HFD3_k127_7133672_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 284.0
HFD3_k127_7133672_3 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000007593 222.0
HFD3_k127_7133672_4 PAS domain K07716,K11357 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.00000000000000003088 83.0
HFD3_k127_7148502_0 PFAM sigma-70 region 2 domain protein K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 387.0
HFD3_k127_7148502_1 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 316.0
HFD3_k127_7148502_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 295.0
HFD3_k127_7148502_3 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000000000000000008548 177.0
HFD3_k127_7148502_4 YCII-related domain - - - 0.00000000000000000000000000000000001711 139.0
HFD3_k127_7148502_5 translation initiation factor activity K06996 - - 0.0000000000000000000000001686 110.0
HFD3_k127_7148502_6 translation initiation factor activity K06996 - - 0.000001657 51.0
HFD3_k127_7148502_7 - - - - 0.000005002 50.0
HFD3_k127_7180820_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006 - 2.7.9.1 0.0 1072.0
HFD3_k127_7180820_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 549.0
HFD3_k127_719812_0 General secretory system II protein E domain protein K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 580.0
HFD3_k127_719812_1 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009726 564.0
HFD3_k127_719812_2 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 518.0
HFD3_k127_719812_3 - - - - 0.000000000000000000000000000002726 135.0
HFD3_k127_719812_4 Type II/IV secretion system protein K02669 - - 0.000000000001937 69.0
HFD3_k127_7204704_0 Domain of unknown function (DUF4388) - - - 0.00000000002432 68.0
HFD3_k127_7204704_1 Domain of unknown function (DUF4388) - - - 0.000001627 52.0
HFD3_k127_7204704_2 Roadblock/LC7 domain - - - 0.00006702 52.0
HFD3_k127_7204704_3 Roadblock LC7 family protein K07131 GO:0001101,GO:0003674,GO:0005085,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0009719,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0019899,GO:0023051,GO:0023056,GO:0032006,GO:0032008,GO:0032947,GO:0042221,GO:0043200,GO:0044464,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051020,GO:0051716,GO:0065007,GO:0065009,GO:0070887,GO:0071229,GO:0071230,GO:0071310,GO:0071417,GO:0071495,GO:0098772,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 - 0.00009212 50.0
HFD3_k127_7210769_0 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008841 379.0
HFD3_k127_7210769_1 ABC-type multidrug transport system ATPase and permease K06147,K06148,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000009907 246.0
HFD3_k127_7210769_2 Dehydrogenase E1 component K11381 - 1.2.4.4 0.0000000001235 63.0
HFD3_k127_7215808_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 383.0
HFD3_k127_7215808_1 Peptidase family M23 K21472 - - 0.00000000000000000000000000000000000000000000001414 179.0
HFD3_k127_7215808_2 DNA-templated transcription, initiation K03088 - - 0.000000000000000000001377 96.0
HFD3_k127_7219916_0 PFAM Peptidase M16 inactive domain K07263 - - 7.793e-267 851.0
HFD3_k127_7219916_1 tRNA (guanine-N7-)-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006466 270.0
HFD3_k127_7231173_0 DHH family K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 607.0
HFD3_k127_7231173_1 Zn-ribbon protein possibly nucleic acid-binding K07164 - - 0.0000000000000000000003438 100.0
HFD3_k127_7246295_0 Cys/Met metabolism PLP-dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 544.0
HFD3_k127_7246295_1 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008958 386.0
HFD3_k127_7246295_2 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 332.0
HFD3_k127_7246295_3 Part of the ABC transporter FtsEX involved in K09811 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 313.0
HFD3_k127_7246295_4 ABC transporter K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005949 288.0
HFD3_k127_7246295_5 - - - - 0.00000000000000000000000000000000000000000001028 170.0
HFD3_k127_7246295_6 Peptidase family M23 - - - 0.0000000000000000000000000000000000000005504 160.0
HFD3_k127_7246295_7 - - - - 0.00000000000000002977 87.0
HFD3_k127_7250998_0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000341 273.0
HFD3_k127_7250998_1 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002587 257.0
HFD3_k127_7250998_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000002355 236.0
HFD3_k127_7250998_3 Low molecular weight phosphatase family K01104 - 3.1.3.48 0.0000000000000000000000000000000000001197 145.0
HFD3_k127_7264220_0 - - - - 1.346e-202 657.0
HFD3_k127_7264220_1 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008357 314.0
HFD3_k127_7264220_2 ABC transporter K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007807 291.0
HFD3_k127_7264220_3 - - - - 0.0000000000000000000000000000000004604 141.0
HFD3_k127_7264220_4 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000002545 129.0
HFD3_k127_7264220_5 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000001734 87.0
HFD3_k127_7266633_0 Part of a membrane complex involved in electron transport K00347,K03614 - 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 325.0
HFD3_k127_7266633_1 Part of a membrane complex involved in electron transport K03615 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000167 259.0
HFD3_k127_7266633_2 Part of a membrane complex involved in electron transport - - - 0.00000000000000000000000000000000002197 145.0
HFD3_k127_7269022_0 Glycoside Hydrolase - - - 5.633e-246 774.0
HFD3_k127_7269022_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000003507 231.0
HFD3_k127_7269022_2 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.000000000000000000000000000000000000000000000000000000000008772 216.0
HFD3_k127_7269022_3 Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor K00697 - 2.4.1.15,2.4.1.347 0.00000000000000000000000000000000000000000000000003606 181.0
HFD3_k127_7299082_0 PFAM polysaccharide biosynthesis protein K03328 - - 0.0000000000000000000000000000000000000000000000000000000000000128 230.0
HFD3_k127_7299082_1 - - - - 0.0000000006524 67.0
HFD3_k127_7322309_0 protein histidine kinase activity K03407,K12257 - 2.7.13.3 0.0 1680.0
HFD3_k127_7322309_1 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 520.0
HFD3_k127_7322309_2 protein-glutamate O-methyltransferase activity K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 420.0
HFD3_k127_7322309_3 protein-glutamate methylesterase activity K03412,K03413 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000007101 201.0
HFD3_k127_7325756_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 428.0
HFD3_k127_7325756_1 HEAT repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 402.0
HFD3_k127_7325756_2 Divergent 4Fe-4S mono-cluster - - - 0.00000000000000003206 83.0
HFD3_k127_7362740_0 alpha/beta hydrolase fold K14731 - 3.1.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 291.0
HFD3_k127_7362740_1 - - - - 0.000000000000000000000000000000000009861 146.0
HFD3_k127_7364535_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 9.44e-261 809.0
HFD3_k127_7364535_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 400.0
HFD3_k127_7364535_2 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006145 349.0
HFD3_k127_7364535_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00000000000000000000000000008603 117.0
HFD3_k127_7364535_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000000000000001749 83.0
HFD3_k127_7366912_0 PglZ domain - - - 2.184e-277 859.0
HFD3_k127_7366912_1 ABC transporter transmembrane region K11085 - - 1.432e-233 737.0
HFD3_k127_7366912_10 DUF based on E. rectale Gene description (DUF3880) K06320 - - 0.000005824 57.0
HFD3_k127_7366912_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 315.0
HFD3_k127_7366912_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000005611 256.0
HFD3_k127_7366912_4 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000000000000000000119 222.0
HFD3_k127_7366912_5 transferase activity, transferring glycosyl groups K13057 - 2.4.1.245 0.00000000000000000000000000000000000000000000000000000000002292 219.0
HFD3_k127_7366912_6 Glycosyl transferase family 2 K12984 - - 0.0000000000000000000000000000000000000000000000000000009177 201.0
HFD3_k127_7366912_7 - - - - 0.00000000000000000000000000007617 123.0
HFD3_k127_7366912_8 - - - - 0.0000000001368 67.0
HFD3_k127_7366912_9 protein kinase activity - - - 0.00000005289 55.0
HFD3_k127_7378221_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003183 594.0
HFD3_k127_7378221_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008923 278.0
HFD3_k127_7378221_2 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000001001 224.0
HFD3_k127_7378221_3 Suf system fes assembly protein, nifu family K04488 - - 0.00000000000000000000000000000000000000001425 157.0
HFD3_k127_7383936_0 Sugar (and other) transporter - - - 4.184e-204 642.0
HFD3_k127_7383936_1 Beta-lactamase K17836 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 323.0
HFD3_k127_7383936_2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 309.0
HFD3_k127_7383936_3 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000000000001565 192.0
HFD3_k127_7383936_4 DUF218 domain - - - 0.000000000000000000000000000000000005253 148.0
HFD3_k127_7398392_0 Sulfate permease family K03321 - - 5.144e-225 710.0
HFD3_k127_7398392_1 Putative modulator of DNA gyrase - - - 6.381e-201 633.0
HFD3_k127_7399003_0 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 342.0
HFD3_k127_7399003_1 ECF sigma factor K03088 - - 0.0000000000000000000000000000000000000000000000000002793 187.0
HFD3_k127_7399003_2 - - - - 0.0000000000000000000000002992 113.0
HFD3_k127_7399003_3 Domain present in PSD-95, Dlg, and ZO-1/2. K04771 - 3.4.21.107 0.000000000000000000001572 104.0
HFD3_k127_7399003_4 Alpha/beta hydrolase family K01259 - 3.4.11.5 0.00000000000001646 75.0
HFD3_k127_7399898_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 495.0
HFD3_k127_7399898_1 isocitrate K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 372.0
HFD3_k127_7399898_2 alginic acid biosynthetic process K10297 - - 0.00003744 48.0
HFD3_k127_7403467_0 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009085 407.0
HFD3_k127_7403467_1 - - - - 0.0000000000000000000119 91.0
HFD3_k127_7403467_2 - - - - 0.000000000006911 67.0
HFD3_k127_7424134_0 Sugar (and other) transporter K03446 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 571.0
HFD3_k127_7424134_1 Biotin-lipoyl like K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 364.0
HFD3_k127_7424134_2 - - - - 0.000000000000000000000000000000000000000000004294 172.0
HFD3_k127_7424134_3 PFAM peptidylprolyl isomerase FKBP-type K01802 - 5.2.1.8 0.00000000000000000000000001075 113.0
HFD3_k127_7460294_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 356.0
HFD3_k127_7460294_1 Protein of unknown function (DUF456) K09793 - - 0.000000000000000000000000000000000000005439 157.0
HFD3_k127_7461160_0 NADH:flavin oxidoreductase / NADH oxidase family - - - 7.197e-194 609.0
HFD3_k127_7461160_1 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009736 265.0
HFD3_k127_7461160_2 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.000000000000168 71.0
HFD3_k127_7468908_0 PFAM ThiJ PfpI domain protein K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002335 269.0
HFD3_k127_7468908_1 Phosphoesterase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002761 261.0
HFD3_k127_7468908_2 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000004488 229.0
HFD3_k127_7468908_3 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000003906 119.0
HFD3_k127_7468908_4 Dodecin K09165 - - 0.000000000000000000001521 97.0
HFD3_k127_7471925_0 Aldo Keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 411.0
HFD3_k127_7471925_1 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 372.0
HFD3_k127_7471925_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003947 359.0
HFD3_k127_7471925_3 tail specific protease K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001144 303.0
HFD3_k127_7471925_4 DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003764 282.0
HFD3_k127_7471925_5 Releases the N-terminal proline from various substrates K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004341 280.0
HFD3_k127_7471925_6 Cysteine-rich motif following a subset of SET domains K07117 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006784 259.0
HFD3_k127_7471925_7 PFAM Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000002937 201.0
HFD3_k127_7471925_8 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000001462 168.0
HFD3_k127_7471925_9 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000004484 150.0
HFD3_k127_7481392_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 3.576e-200 632.0
HFD3_k127_7481392_1 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 297.0
HFD3_k127_7481392_2 - - - - 0.0000000000000000000000001954 114.0
HFD3_k127_7489408_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 562.0
HFD3_k127_7502124_0 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 371.0
HFD3_k127_7502124_1 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 356.0
HFD3_k127_7502124_2 Bacterial regulatory proteins, tetR family - - - 0.000000000008587 68.0
HFD3_k127_752081_0 xanthine dehydrogenase activity - - - 6.079e-205 642.0
HFD3_k127_752081_1 XdhC and CoxI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 438.0
HFD3_k127_752081_2 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000121 291.0
HFD3_k127_752081_3 MobA-Related Protein K00087,K07141,K07402,K19190 - 1.1.1.328,1.17.1.4,2.7.7.76 0.00000000000000000000000000000000000000000002339 175.0
HFD3_k127_7523087_0 Phosphoglycerate kinase K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 539.0
HFD3_k127_7523087_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 326.0
HFD3_k127_7523087_2 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000002317 260.0
HFD3_k127_7537573_0 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 599.0
HFD3_k127_7537573_1 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000002098 261.0
HFD3_k127_7537573_2 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.00000000000000000000000000000000007071 144.0
HFD3_k127_7542750_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 396.0
HFD3_k127_7542750_1 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 383.0
HFD3_k127_7542750_2 Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000000000000000000000001745 139.0
HFD3_k127_7568919_0 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000578 572.0
HFD3_k127_7568919_1 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 476.0
HFD3_k127_7568919_2 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 441.0
HFD3_k127_7578729_0 von Willebrand factor type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000001699 194.0
HFD3_k127_7578729_1 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000001357 142.0
HFD3_k127_7581452_0 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000679 198.0
HFD3_k127_7581452_1 methyltransferase - - - 0.000000000000000000000000000967 119.0
HFD3_k127_7581452_2 peroxidase activity K00435 - - 0.0000000000000000005084 91.0
HFD3_k127_761216_0 Heat shock 70 kDa protein K04043 - - 7.091e-269 833.0
HFD3_k127_761216_1 PDZ domain (Also known as DHR or GLGF) K04771 - 3.4.21.107 0.00004194 54.0
HFD3_k127_7629278_0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001557 267.0
HFD3_k127_7629278_1 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000004279 164.0
HFD3_k127_7629278_2 pathogenesis - - - 0.000000000000000000000000000000000000000008236 165.0
HFD3_k127_7629278_3 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000004936 150.0
HFD3_k127_7642160_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 540.0
HFD3_k127_7642160_1 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000002039 115.0
HFD3_k127_7647552_0 palmitoyl-(protein) hydrolase activity K06999,K15975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001362 263.0
HFD3_k127_7647552_1 diguanylate cyclase activity K13069 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0052621 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000002209 225.0
HFD3_k127_7647552_2 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000001558 191.0
HFD3_k127_7666796_0 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 481.0
HFD3_k127_7666796_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 409.0
HFD3_k127_7666796_2 secondary active sulfate transmembrane transporter activity K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000597 316.0
HFD3_k127_7667557_0 PFAM ABC transporter related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004805 377.0
HFD3_k127_7667557_1 PFAM secretion protein HlyD family protein K01993,K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006189 312.0
HFD3_k127_7667557_2 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000008232 228.0
HFD3_k127_7667557_3 PFAM ABC transporter K01990,K01992,K09695 - - 0.000000000000000000000005637 104.0
HFD3_k127_7668013_0 AcrB/AcrD/AcrF family K03296 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 419.0
HFD3_k127_7668013_1 PFAM Chlorite dismutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001858 263.0
HFD3_k127_7675995_0 HEAT repeats - - - 0.000000000000000000000000000000000000000000000000005085 196.0
HFD3_k127_7675995_1 HEAT repeats - - - 0.00000000000000000000000000000000000000056 151.0
HFD3_k127_7676117_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 2.123e-232 726.0
HFD3_k127_7676117_1 Transglycosylase associated protein - - - 0.0000000000000000002129 90.0
HFD3_k127_7676117_2 Transglycosylase associated protein - - - 0.0001857 44.0
HFD3_k127_7713923_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 441.0
HFD3_k127_7713923_1 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000001912 225.0
HFD3_k127_7727665_0 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004688 263.0
HFD3_k127_7727665_1 Amidinotransferase K01478 - 3.5.3.6 0.000000000000000000000000000000000000000000000000000000000000000000001035 250.0
HFD3_k127_7740616_0 PFAM Type II secretion system protein E K02652 - - 5.226e-230 724.0
HFD3_k127_789701_0 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000452 501.0
HFD3_k127_78977_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 8.701e-224 699.0
HFD3_k127_78977_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003747 280.0
HFD3_k127_78977_2 Metallopeptidase family M24 K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000003133 232.0
HFD3_k127_808147_0 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 1.037e-200 640.0
HFD3_k127_808147_1 Rieske (2fe-2S) K00499 - 1.14.15.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005282 380.0
HFD3_k127_808147_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000001096 259.0
HFD3_k127_808147_3 DinB family - - - 0.000000000000000000000000000000000000000000000000008436 186.0
HFD3_k127_808681_0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 546.0
HFD3_k127_808681_1 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000000000000001317 206.0
HFD3_k127_808681_2 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000004335 184.0
HFD3_k127_808681_3 Bacillithiol biosynthesis BshC K22136 - - 0.0000000000000000000000002371 109.0
HFD3_k127_822716_0 M61 glycyl aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 551.0
HFD3_k127_822716_1 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006175 252.0
HFD3_k127_822716_2 - - - - 0.000000000000000000000000000000000000000000000000000001262 200.0
HFD3_k127_822716_3 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00003119 51.0
HFD3_k127_828375_0 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007258 370.0
HFD3_k127_828375_1 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000000000000001739 178.0
HFD3_k127_832405_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 7.129e-232 722.0
HFD3_k127_832405_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 287.0
HFD3_k127_838700_0 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002844 291.0
HFD3_k127_838700_1 transferase activity, transferring glycosyl groups K00786 - - 0.00000000000000000000000000000000000000000000000000000000000000000005919 240.0
HFD3_k127_855369_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005053 319.0
HFD3_k127_855369_1 Nodulation protein S (NodS) - - - 0.00000000000000000000000000000000000000000000000000001843 194.0
HFD3_k127_855369_2 Peptidase family M28 - - - 0.00000000000000000000001789 101.0
HFD3_k127_895804_0 Helix-hairpin-helix motif K02337 - 2.7.7.7 0.0 1334.0
HFD3_k127_914703_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000577 388.0
HFD3_k127_914703_1 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 329.0
HFD3_k127_914703_2 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000001786 169.0
HFD3_k127_914703_3 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000003132 166.0
HFD3_k127_914703_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.0000000000000000000000000000000000000000000279 162.0
HFD3_k127_932419_0 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 480.0
HFD3_k127_932419_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000007378 269.0
HFD3_k127_932419_2 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000007715 160.0
HFD3_k127_939608_0 FMN-dependent dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 461.0
HFD3_k127_939608_1 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007391 359.0
HFD3_k127_939608_2 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000002588 195.0
HFD3_k127_939608_3 GDP-mannose mannosyl hydrolase activity K01858,K03207,K03574 - 3.6.1.55,5.5.1.4 0.00000000000000000000000000000000000000000000000000344 186.0
HFD3_k127_939608_4 - - - - 0.000000000000000000000000000000000181 140.0
HFD3_k127_939608_5 - - - - 0.000000000000000000001093 98.0
HFD3_k127_939608_6 Sugar (and other) transporter - - - 0.00000000006764 64.0
HFD3_k127_946678_0 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 410.0
HFD3_k127_946678_1 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003399 285.0
HFD3_k127_951076_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.903e-221 721.0
HFD3_k127_951076_1 SurA N-terminal domain K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 387.0
HFD3_k127_951076_2 PPIC-type PPIASE domain K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 368.0
HFD3_k127_951076_3 Pyridoxal phosphate biosynthetic protein PdxA K00097 - 1.1.1.262 0.000000000000000004877 87.0
HFD3_k127_990022_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 1.444e-195 616.0
HFD3_k127_990022_1 Peptidase M16 inactive domain K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006971 480.0
HFD3_k127_990022_2 protein tyrosine kinase activity K16692 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 328.0
HFD3_k127_990022_3 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006137 280.0
HFD3_k127_990022_4 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006084 273.0
HFD3_k127_990022_5 Domain present in phytochromes and cGMP-specific phosphodiesterases. K08968 - 1.8.4.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000618 258.0
HFD3_k127_990022_6 Copper binding proteins, plastocyanin/azurin family K02638 - - 0.00000000000000000000000000000000000000000000000000000000000000006381 226.0
HFD3_k127_990022_7 - - - - 0.000000000000000000000000000000000000000000001018 169.0
HFD3_k127_990022_8 Cold shock protein domain K03704 - - 0.00000000000000000000000000000000001659 136.0