Overview

ID MAG01683
Name HFD3_bin.23
Sample SMP0045
Taxonomy
Kingdom Bacteria
Phylum Desulfobacterota_E
Class Deferrimicrobia
Order Deferrimicrobiales
Family Deferrimicrobiaceae
Genus FEB-35
Species
Assembly information
Completeness (%) 96.6
Contamination (%) 4.8
GC content (%) 65.0
N50 (bp) 16,537
Genome size (bp) 2,593,667

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2492

Gene name Description KEGG GOs EC E-value Score Sequence
HFD3_k127_1036595_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 3.541e-317 978.0
HFD3_k127_1036595_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 3.316e-253 790.0
HFD3_k127_1036595_10 Belongs to the EPSP synthase family. MurA subfamily K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009122 474.0
HFD3_k127_1036595_11 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008336 427.0
HFD3_k127_1036595_12 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 430.0
HFD3_k127_1036595_13 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004967 431.0
HFD3_k127_1036595_14 SIS domain K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 411.0
HFD3_k127_1036595_15 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 395.0
HFD3_k127_1036595_16 Histidinol dehydrogenase K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 371.0
HFD3_k127_1036595_17 Mur ligase middle domain K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 366.0
HFD3_k127_1036595_18 PFAM peptidase S1 and S6, chymotrypsin Hap K04771,K04772 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009501 366.0
HFD3_k127_1036595_19 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 353.0
HFD3_k127_1036595_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 9.927e-209 655.0
HFD3_k127_1036595_20 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007085 343.0
HFD3_k127_1036595_21 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004604 338.0
HFD3_k127_1036595_22 Mur ligase family, catalytic domain K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 332.0
HFD3_k127_1036595_23 PFAM ABC transporter related K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 308.0
HFD3_k127_1036595_24 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 316.0
HFD3_k127_1036595_25 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007079 294.0
HFD3_k127_1036595_26 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005437 293.0
HFD3_k127_1036595_27 S4 RNA-binding domain K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001139 282.0
HFD3_k127_1036595_28 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000405 274.0
HFD3_k127_1036595_29 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000003711 264.0
HFD3_k127_1036595_3 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007075 609.0
HFD3_k127_1036595_30 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000003233 259.0
HFD3_k127_1036595_31 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000001393 254.0
HFD3_k127_1036595_32 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000002268 254.0
HFD3_k127_1036595_33 Protein of unknown function (DUF1385) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003716 250.0
HFD3_k127_1036595_34 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000003894 250.0
HFD3_k127_1036595_35 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000001148 253.0
HFD3_k127_1036595_36 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000002616 239.0
HFD3_k127_1036595_37 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000002808 240.0
HFD3_k127_1036595_38 imidazoleglycerol-phosphate dehydratase activity K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000001827 237.0
HFD3_k127_1036595_39 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000006225 213.0
HFD3_k127_1036595_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008208 618.0
HFD3_k127_1036595_40 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000000000000002214 201.0
HFD3_k127_1036595_41 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.0000000000000000000000000000000000000000000000000001152 196.0
HFD3_k127_1036595_42 PFAM permease YjgP YjgQ family protein K07091 - - 0.0000000000000000000000000000000000000000000000001545 193.0
HFD3_k127_1036595_43 PFAM permease YjgP YjgQ family protein K11720 - - 0.0000000000000000000000000000000000000000000000618 192.0
HFD3_k127_1036595_44 Ribosomal protein K02871 GO:0000313,GO:0000315,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005762,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0031974,GO:0032543,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013,GO:0071704,GO:0097159,GO:0098798,GO:0140053,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000005671 173.0
HFD3_k127_1036595_45 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000000000000000000000000000000001287 159.0
HFD3_k127_1036595_46 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000000000000000000403 162.0
HFD3_k127_1036595_47 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.0000000000000000000000000000000000003639 144.0
HFD3_k127_1036595_48 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000001491 147.0
HFD3_k127_1036595_49 C4-type zinc ribbon domain K07164 - - 0.000000000000000000000000000000000001521 158.0
HFD3_k127_1036595_5 PEP-utilising enzyme, N-terminal K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 570.0
HFD3_k127_1036595_50 Belongs to the MraZ family K03925 - - 0.00000000000000000000000000000000003277 139.0
HFD3_k127_1036595_51 Yqey-like protein K09117 - - 0.0000000000000000000000000000000004925 135.0
HFD3_k127_1036595_52 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000001148 143.0
HFD3_k127_1036595_53 Reverse transcriptase-like K03469,K06864,K22316 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.73 0.00000000000000000000000000000006456 133.0
HFD3_k127_1036595_54 PFAM PTS system mannose fructose sorbose family IID component K02796 - - 0.0000000000000000000000000000009512 137.0
HFD3_k127_1036595_55 PFAM PTS system fructose subfamily IIA component K02793 - 2.7.1.191 0.000000000000000000000000000001979 138.0
HFD3_k127_1036595_56 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.00000000000000000000000000002166 124.0
HFD3_k127_1036595_57 Belongs to the multicopper oxidase YfiH RL5 family K05810 GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0046983,GO:0055114 - 0.0000000000000000000000000002366 124.0
HFD3_k127_1036595_58 PFAM PTS system sorbose subfamily IIB component K02794 - 2.7.1.191 0.000000000000000000000000001058 125.0
HFD3_k127_1036595_59 Binds the 23S rRNA K02909 - - 0.0000000000000000000000003721 106.0
HFD3_k127_1036595_6 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 519.0
HFD3_k127_1036595_60 PTS system sorbose-specific iic component K02795 - - 0.0000000000000000000000008554 117.0
HFD3_k127_1036595_61 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000005035 103.0
HFD3_k127_1036595_62 - - - - 0.00000000000000000000007767 100.0
HFD3_k127_1036595_63 PTS HPr component phosphorylation site K11189 - - 0.000000000000000000001029 108.0
HFD3_k127_1036595_64 EAL domain - - - 0.00000000000000000004959 102.0
HFD3_k127_1036595_65 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 GO:0003674,GO:0003824,GO:0004731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016154,GO:0016740,GO:0016757,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.1,2.4.2.2 0.0000000000000000002788 90.0
HFD3_k127_1036595_67 cell division K03586 GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0019954,GO:0022402,GO:0022414,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0043093,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944 - 0.0005903 52.0
HFD3_k127_1036595_7 PASTA domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 534.0
HFD3_k127_1036595_8 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 502.0
HFD3_k127_1036595_9 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 500.0
HFD3_k127_1040564_0 nitric oxide reductase activity K22405 - 1.6.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 577.0
HFD3_k127_1040564_1 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 524.0
HFD3_k127_1040564_10 Protein of unknown function DUF47 K02039,K07220 GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.000000000000000000000000000000000000000000000000000000000000000000005658 240.0
HFD3_k127_1040564_11 ATP corrinoid adenosyltransferase K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000002104 213.0
HFD3_k127_1040564_12 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000007343 199.0
HFD3_k127_1040564_13 MGS-like domain K01734 - 4.2.3.3 0.0000000000000000000000000000000000000000003854 162.0
HFD3_k127_1040564_14 the in vivo substrate is - - - 0.000000000000000000000000000000000005357 146.0
HFD3_k127_1040564_15 regulation of single-species biofilm formation K02342,K03763,K13573 - 2.7.7.7 0.000000000000000000000000000001516 126.0
HFD3_k127_1040564_16 Rubredoxin - - - 0.00000000000000000000000126 103.0
HFD3_k127_1040564_17 Rubrerythrin - - - 0.000000000007118 67.0
HFD3_k127_1040564_2 Chromate K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008469 483.0
HFD3_k127_1040564_3 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 422.0
HFD3_k127_1040564_4 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 373.0
HFD3_k127_1040564_5 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008491 334.0
HFD3_k127_1040564_6 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 316.0
HFD3_k127_1040564_7 histidine kinase HAMP region domain protein K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008195 327.0
HFD3_k127_1040564_8 TIGRFAM phosphate ABC transporter K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002192 295.0
HFD3_k127_1040564_9 Transcriptional regulatory protein, C terminal K07658 - - 0.000000000000000000000000000000000000000000000000000000000000000000001491 245.0
HFD3_k127_1065748_0 Homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 465.0
HFD3_k127_1065748_1 PFAM Aminotransferase class I and II K10206,K14261 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 324.0
HFD3_k127_1065748_2 Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 291.0
HFD3_k127_1075644_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 1.552e-230 726.0
HFD3_k127_1075644_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 562.0
HFD3_k127_1075644_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 326.0
HFD3_k127_1075644_3 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005374 306.0
HFD3_k127_1124880_0 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 2.195e-198 635.0
HFD3_k127_1124880_1 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000001454 265.0
HFD3_k127_1124880_2 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000002575 232.0
HFD3_k127_1124880_3 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000004738 218.0
HFD3_k127_1124880_4 Thiamine-binding protein - - - 0.00000000000000000000000000000000000222 139.0
HFD3_k127_1124880_5 - - - - 0.00000000000002333 81.0
HFD3_k127_1124880_6 - - - - 0.0000000000004982 77.0
HFD3_k127_118675_0 Branched-chain amino acid transport system / permease component K01997,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 441.0
HFD3_k127_118675_1 PFAM ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001333 283.0
HFD3_k127_118675_2 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component - - - 0.000000000000000000000000000000000000000000000000000000000000001815 244.0
HFD3_k127_118675_3 CoA-transferase family III - - - 0.0000000000001684 73.0
HFD3_k127_1244924_0 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 481.0
HFD3_k127_1244924_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 390.0
HFD3_k127_1244924_2 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007567 344.0
HFD3_k127_1244924_3 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000001728 240.0
HFD3_k127_1244924_4 GYD domain - - - 0.000000000000000000000000000000000004239 140.0
HFD3_k127_1244924_5 NAD(P)H-binding K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000003423 125.0
HFD3_k127_1279821_0 Putative citrate transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 469.0
HFD3_k127_1279821_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 461.0
HFD3_k127_1279821_2 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 290.0
HFD3_k127_1279821_3 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001366 289.0
HFD3_k127_1279821_4 Peptidase dimerisation domain K13049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007462 273.0
HFD3_k127_1279821_5 SURF4 family K15977 - - 0.0000000000000000000000000004501 117.0
HFD3_k127_1279821_6 Universal stress protein family - - - 0.0000001658 62.0
HFD3_k127_136474_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1959.0
HFD3_k127_136474_1 RNA polymerase beta subunit external 1 domain K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1773.0
HFD3_k127_136474_10 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000004218 84.0
HFD3_k127_136474_11 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000004403 81.0
HFD3_k127_136474_12 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000002472 75.0
HFD3_k127_136474_13 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000000000001485 72.0
HFD3_k127_136474_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1037.0
HFD3_k127_136474_3 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 321.0
HFD3_k127_136474_4 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000001395 247.0
HFD3_k127_136474_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000005952 221.0
HFD3_k127_136474_6 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000008257 214.0
HFD3_k127_136474_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000006706 210.0
HFD3_k127_136474_8 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000005705 161.0
HFD3_k127_136474_9 Ribosomal protein L10 K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000002119 138.0
HFD3_k127_1368523_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.047e-224 724.0
HFD3_k127_1368523_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 578.0
HFD3_k127_1368523_10 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000172 284.0
HFD3_k127_1368523_11 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000213 222.0
HFD3_k127_1368523_12 Cytidylate kinase K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000002076 214.0
HFD3_k127_1368523_13 Bis-adenosyl-polyphosphate hydrolase, FHIT domain-containing K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000000000853 179.0
HFD3_k127_1368523_14 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000001325 130.0
HFD3_k127_1368523_15 bacterial (prokaryotic) histone like domain K05788 - - 0.0000000000000000000000000000003384 125.0
HFD3_k127_1368523_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000948 581.0
HFD3_k127_1368523_3 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 427.0
HFD3_k127_1368523_4 amino acid-binding ACT domain protein K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 434.0
HFD3_k127_1368523_5 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 421.0
HFD3_k127_1368523_6 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 394.0
HFD3_k127_1368523_7 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 297.0
HFD3_k127_1368523_8 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 289.0
HFD3_k127_1368523_9 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001638 300.0
HFD3_k127_1481794_0 CoA binding domain K09181 - - 0.0 1117.0
HFD3_k127_1481794_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain - - - 0.0 1075.0
HFD3_k127_1481794_10 6-phosphofructokinase activity K00850,K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004486 475.0
HFD3_k127_1481794_11 BadF/BadG/BcrA/BcrD ATPase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004528 416.0
HFD3_k127_1481794_12 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074,K15016 - 1.1.1.157,1.1.1.35,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 421.0
HFD3_k127_1481794_13 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 417.0
HFD3_k127_1481794_14 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 392.0
HFD3_k127_1481794_15 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 356.0
HFD3_k127_1481794_16 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 351.0
HFD3_k127_1481794_17 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004306 325.0
HFD3_k127_1481794_18 ACT domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001505 229.0
HFD3_k127_1481794_19 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000001603 198.0
HFD3_k127_1481794_2 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 8.51e-233 735.0
HFD3_k127_1481794_20 Thioesterase K01075,K07107,K12073 - 3.1.2.23,3.1.2.28 0.0000000000000000000009262 107.0
HFD3_k127_1481794_3 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 1.745e-230 719.0
HFD3_k127_1481794_4 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 6.056e-228 717.0
HFD3_k127_1481794_5 Belongs to the thiolase family - - - 1.002e-220 688.0
HFD3_k127_1481794_6 AMP-binding enzyme C-terminal domain - - - 1.027e-217 687.0
HFD3_k127_1481794_7 Alanine dehydrogenase/PNT, C-terminal domain K07538 - 1.1.1.368 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008277 580.0
HFD3_k127_1481794_8 Amino acid amide ABC transporter substrate-binding protein, HAAT family K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 541.0
HFD3_k127_1481794_9 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 511.0
HFD3_k127_1515079_0 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000001561 169.0
HFD3_k127_1515079_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000003296 127.0
HFD3_k127_1515079_2 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000001543 125.0
HFD3_k127_1515079_3 Domain of Unknown function (DUF542) K07322 - - 0.000000000000000002679 85.0
HFD3_k127_1515079_4 Cupin 2, conserved barrel domain protein - - - 0.00000000000000033 82.0
HFD3_k127_1515079_5 Cytochrome C and Quinol oxidase polypeptide I K15862 - 1.9.3.1 0.00000000000002162 78.0
HFD3_k127_1515079_6 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00007439 46.0
HFD3_k127_1515079_7 SNARE associated Golgi protein - - - 0.0001479 46.0
HFD3_k127_151893_0 exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 512.0
HFD3_k127_151893_1 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 359.0
HFD3_k127_151893_2 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000000000000000679 108.0
HFD3_k127_151893_3 HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.0000000194 59.0
HFD3_k127_151893_4 signal sequence binding K07152 - - 0.00001543 51.0
HFD3_k127_1528982_0 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 403.0
HFD3_k127_1528982_1 Psort location CytoplasmicMembrane, score K07793 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 319.0
HFD3_k127_1528982_2 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001339 266.0
HFD3_k127_1528982_3 Protein of unknown function (DUF1343) - - - 0.00000000000000000000000000000000000000000000000002647 183.0
HFD3_k127_1528982_4 protein with SCP PR1 domains - - - 0.000000000000000000000000000000007847 133.0
HFD3_k127_1569202_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1073.0
HFD3_k127_1569202_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.228e-284 896.0
HFD3_k127_1569202_10 Nucleotidyl transferase K04042,K11528 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009526 403.0
HFD3_k127_1569202_11 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 377.0
HFD3_k127_1569202_12 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 381.0
HFD3_k127_1569202_13 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006147 334.0
HFD3_k127_1569202_14 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005024 322.0
HFD3_k127_1569202_15 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009965 314.0
HFD3_k127_1569202_16 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 306.0
HFD3_k127_1569202_17 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001619 284.0
HFD3_k127_1569202_18 Histidine kinase A domain protein K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002436 299.0
HFD3_k127_1569202_19 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000002571 240.0
HFD3_k127_1569202_2 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 2.307e-273 881.0
HFD3_k127_1569202_20 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000005 254.0
HFD3_k127_1569202_21 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000008994 172.0
HFD3_k127_1569202_22 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000000000000000000000005642 164.0
HFD3_k127_1569202_23 EVE domain - - - 0.00000000000000000000000000000000000000001062 160.0
HFD3_k127_1569202_24 Cobalamin biosynthesis protein cbiG - - - 0.00000000000000000000000000000000000000001411 166.0
HFD3_k127_1569202_25 PIN domain - - - 0.0000000000000000000000000000000001395 137.0
HFD3_k127_1569202_26 Uncharacterized conserved protein (DUF2277) - - - 0.0000000000000000000000000000004129 128.0
HFD3_k127_1569202_27 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.00000000000000000000000001531 115.0
HFD3_k127_1569202_28 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000001734 120.0
HFD3_k127_1569202_29 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000004597 121.0
HFD3_k127_1569202_3 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 4.794e-250 787.0
HFD3_k127_1569202_30 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.0000000000000000000000006605 113.0
HFD3_k127_1569202_31 Two component transcriptional regulator, winged helix family K02483,K07657 - - 0.00000000000000000000003934 102.0
HFD3_k127_1569202_32 SpoVT / AbrB like domain - - - 0.0000000000000000002839 91.0
HFD3_k127_1569202_33 cheY-homologous receiver domain - - - 0.000000000000000001455 94.0
HFD3_k127_1569202_34 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000557 89.0
HFD3_k127_1569202_35 Ribosomal protein L34 K02914 - - 0.0000000000001196 72.0
HFD3_k127_1569202_36 Magnesium chelatase, subunit ChlI K03404,K03405 - 6.6.1.1 0.0000000000006473 69.0
HFD3_k127_1569202_37 ATP synthase B/B' CF(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000009098 70.0
HFD3_k127_1569202_38 domain, Protein - - - 0.000000005448 69.0
HFD3_k127_1569202_39 Putative zinc-finger - - - 0.00000007397 64.0
HFD3_k127_1569202_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 4.881e-247 781.0
HFD3_k127_1569202_40 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000008603 63.0
HFD3_k127_1569202_41 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000006183 58.0
HFD3_k127_1569202_42 Tetratricopeptide repeat protein - - - 0.0000744 57.0
HFD3_k127_1569202_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.248e-242 763.0
HFD3_k127_1569202_6 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 4.146e-233 759.0
HFD3_k127_1569202_7 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007581 551.0
HFD3_k127_1569202_8 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 477.0
HFD3_k127_1569202_9 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009094 481.0
HFD3_k127_1571149_0 SMART Elongator protein 3 MiaB NifB - - - 8.819e-212 685.0
HFD3_k127_1571149_1 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000371 559.0
HFD3_k127_1571149_2 sigma factor antagonist activity K04757 - 2.7.11.1 0.0000000000000001405 94.0
HFD3_k127_1577739_0 Belongs to the glycosyl hydrolase 57 family - - - 0.0 1011.0
HFD3_k127_1577739_1 Alpha amylase, catalytic domain K06044 - 5.4.99.15 3.311e-301 952.0
HFD3_k127_1577739_2 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005655 334.0
HFD3_k127_1590368_0 alpha beta alpha domain I K01835 - 5.4.2.2 6.769e-255 803.0
HFD3_k127_1590368_1 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 325.0
HFD3_k127_1590368_10 transferase activity, transferring acyl groups other than amino-acyl groups K03685 - 3.1.26.3 0.0000002191 60.0
HFD3_k127_1590368_2 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 287.0
HFD3_k127_1590368_3 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000001174 263.0
HFD3_k127_1590368_4 Chase2 domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000003 260.0
HFD3_k127_1590368_5 PFAM OmpA MotB domain protein - - - 0.000000000000000000000000000000000000000002611 162.0
HFD3_k127_1590368_6 Membrane - - - 0.00000000000000000000000000000005099 130.0
HFD3_k127_1590368_7 PFAM FecR protein - - - 0.000000000000000000000000000005215 124.0
HFD3_k127_1590368_8 Histone deacetylase domain - - - 0.000000000000000000000001855 104.0
HFD3_k127_1590368_9 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000007567 108.0
HFD3_k127_1612772_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000428 537.0
HFD3_k127_1612772_1 Peptidase U62 modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 464.0
HFD3_k127_1612772_10 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000001035 128.0
HFD3_k127_1612772_11 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K00652,K01935 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004141,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017076,GO:0017144,GO:0018130,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.47,6.3.3.3 0.00000000000000000000000000004681 134.0
HFD3_k127_1612772_12 CAAX protease self-immunity K07052 - - 0.000001111 59.0
HFD3_k127_1612772_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004541 339.0
HFD3_k127_1612772_3 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012,K16180 - 2.8.1.6,5.4.99.58 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005176 333.0
HFD3_k127_1612772_4 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006889 323.0
HFD3_k127_1612772_5 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 291.0
HFD3_k127_1612772_6 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 286.0
HFD3_k127_1612772_7 PFAM extracellular solute-binding protein, family 5 K02035,K13893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003173 254.0
HFD3_k127_1612772_8 HAD-hyrolase-like K01091 - 3.1.3.18 0.000000000000000000000000000000000000000001125 181.0
HFD3_k127_1612772_9 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000000000000000000000000000001512 175.0
HFD3_k127_1649401_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 7.402e-287 888.0
HFD3_k127_1649401_1 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282,K18008 - 1.12.2.1,1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005082 495.0
HFD3_k127_1649401_2 PFAM Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 364.0
HFD3_k127_1649401_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 339.0
HFD3_k127_1649401_4 Belongs to the universal stress protein A family - - - 0.00000000000000000000005928 105.0
HFD3_k127_1673924_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 9.859e-215 693.0
HFD3_k127_1673924_1 Thiolase, C-terminal domain K00626,K07823 - 2.3.1.174,2.3.1.9 5.072e-195 617.0
HFD3_k127_1673924_2 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 333.0
HFD3_k127_1673924_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 301.0
HFD3_k127_1673924_4 SpoIIAA-like - - - 0.000000000000000000000000000000000000000388 153.0
HFD3_k127_1673924_5 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000000004554 109.0
HFD3_k127_1673924_6 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00001248 47.0
HFD3_k127_1673924_7 lactoylglutathione lyase activity - - - 0.00001422 53.0
HFD3_k127_1674582_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.537e-235 738.0
HFD3_k127_1674582_1 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 2.876e-197 657.0
HFD3_k127_1674582_2 phenylalanine-tRNA ligase activity K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 420.0
HFD3_k127_1674582_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.00000000000000000000000000000000000000000000001532 194.0
HFD3_k127_1674582_4 Mannose-6-phosphate isomerase - - - 0.0000000000000000000000000000000000000000000003952 169.0
HFD3_k127_1674582_5 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000006677 152.0
HFD3_k127_1674582_6 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000000000002031 131.0
HFD3_k127_1674582_7 regulatory protein, MerR - - - 0.000000000000000000000556 100.0
HFD3_k127_1674582_8 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000004582 76.0
HFD3_k127_1685996_0 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 464.0
HFD3_k127_1685996_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007543 393.0
HFD3_k127_1685996_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006738 359.0
HFD3_k127_1685996_3 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 309.0
HFD3_k127_1685996_4 Protein of unknown function (DUF3313) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002835 271.0
HFD3_k127_1685996_5 Domain of unknown function (DUF1330) - - - 0.000000000000000000000000000000000000000000000002798 174.0
HFD3_k127_1685996_6 - - - - 0.00000000000000000000000000000000007941 139.0
HFD3_k127_1716431_0 PFAM ribonuclease II K01147 - 3.1.13.1 1.277e-208 664.0
HFD3_k127_1716431_1 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.00000000000000000000000000000004647 128.0
HFD3_k127_1729763_0 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K00404,K15862 GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005488,GO:0005506,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008144,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015975,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0016705,GO:0017144,GO:0019411,GO:0019637,GO:0019646,GO:0019693,GO:0019825,GO:0020037,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045154,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.9.3.1 7.266e-226 708.0
HFD3_k127_1729763_1 Histidine kinase A domain protein - - - 0.0000001174 64.0
HFD3_k127_1729763_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00001796 57.0
HFD3_k127_1729763_3 GGDEF domain - - - 0.0005105 52.0
HFD3_k127_1765802_0 Peptidase family U32 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009667 605.0
HFD3_k127_1765802_1 Chalcone and stilbene synthases, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 437.0
HFD3_k127_1765802_10 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000000000000000000000000000000003356 160.0
HFD3_k127_1765802_11 YceI-like domain - - - 0.00000000000000000000000000000003121 134.0
HFD3_k127_1765802_12 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000004167 126.0
HFD3_k127_1765802_13 Thioesterase superfamily - - - 0.0000000000000000000000000004403 128.0
HFD3_k127_1765802_14 Papain-like cysteine protease AvrRpt2 - - - 0.0000000000000000000000001807 115.0
HFD3_k127_1765802_15 Tetratricopeptide repeat - - - 0.0000000000000000000003414 110.0
HFD3_k127_1765802_16 Thioesterase K01075 - 3.1.2.23 0.000000000000000000003909 107.0
HFD3_k127_1765802_17 belongs to the Fur family K03711 - - 0.0000000000000001795 86.0
HFD3_k127_1765802_18 Putative zinc-finger - - - 0.0000000000005216 80.0
HFD3_k127_1765802_19 - - - - 0.000000004609 59.0
HFD3_k127_1765802_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 322.0
HFD3_k127_1765802_20 gas vesicle protein - - - 0.0000001192 57.0
HFD3_k127_1765802_3 SMART Elongator protein 3 MiaB NifB K07139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 314.0
HFD3_k127_1765802_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008741 278.0
HFD3_k127_1765802_5 penicillin-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001217 272.0
HFD3_k127_1765802_6 AAA domain, putative AbiEii toxin, Type IV TA system K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000002018 248.0
HFD3_k127_1765802_7 Zinc-uptake complex component A periplasmic K09815 - - 0.00000000000000000000000000000000000000000000000000000000424 215.0
HFD3_k127_1765802_8 ABC 3 transport family K09816 - - 0.000000000000000000000000000000000000000000000000000000005054 220.0
HFD3_k127_1765802_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000007998 155.0
HFD3_k127_1766641_0 CoA binding domain K01905,K22224 - 6.2.1.13 1.663e-197 640.0
HFD3_k127_1766641_1 Belongs to the AlaDH PNT family K00259 GO:0000286,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009653,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0030154,GO:0030435,GO:0032502,GO:0043436,GO:0043934,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048646,GO:0048856,GO:0048869,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 361.0
HFD3_k127_1766641_2 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000002785 194.0
HFD3_k127_1766641_3 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.0000000000000000000000000000000000000000000004482 174.0
HFD3_k127_1766641_4 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.00000000000000000000000000000000000001823 167.0
HFD3_k127_1766641_5 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000000000000000002797 109.0
HFD3_k127_1766641_6 sterol carrier protein - - - 0.000000000000000000001651 104.0
HFD3_k127_1766641_7 Short-chain dehydrogenase reductase sdr - - - 0.00000000000000001377 99.0
HFD3_k127_1772925_0 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 382.0
HFD3_k127_1772925_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006496 305.0
HFD3_k127_1772925_2 PFAM NAD-dependent epimerase dehydratase K08678 - 4.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000003182 246.0
HFD3_k127_1795554_0 Uncharacterized ACR, COG1430 K09005 - - 0.000000001379 60.0
HFD3_k127_1795554_1 protein conserved in bacteria - - - 0.000007779 60.0
HFD3_k127_1816993_0 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 497.0
HFD3_k127_1816993_1 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000000000002123 223.0
HFD3_k127_1816993_2 - - - - 0.000000000000000000000000000000000000001796 148.0
HFD3_k127_1816993_3 - - - - 0.00000000000000000000000000000000007585 146.0
HFD3_k127_1816993_4 - - - - 0.0000001229 53.0
HFD3_k127_1816993_5 Belongs to the 'phage' integrase family - - - 0.0002003 45.0
HFD3_k127_1830008_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0 1024.0
HFD3_k127_1830008_1 Bacterial extracellular solute-binding protein K02027,K10236 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 491.0
HFD3_k127_1830008_10 Cytochrome c - - - 0.0000003194 55.0
HFD3_k127_1830008_2 TOBE domain K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006404 371.0
HFD3_k127_1830008_3 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 357.0
HFD3_k127_1830008_4 glycerophosphodiester transmembrane transport K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 337.0
HFD3_k127_1830008_5 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000001449 233.0
HFD3_k127_1830008_6 PFAM FeoA family protein K04758 - - 0.00000000000000000000000000000002769 127.0
HFD3_k127_1830008_7 membrane transporter protein K07090 - - 0.0000000000000000000000434 112.0
HFD3_k127_1830008_8 PFAM FeoA family protein K04758 - - 0.00000000000000003384 85.0
HFD3_k127_184266_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 527.0
HFD3_k127_184266_1 Cupin domain - - - 0.00000000000000000000000000000000000000007411 156.0
HFD3_k127_184266_2 Multicopper oxidase K06324 - 1.16.3.3 0.000000000000000009972 83.0
HFD3_k127_1880149_0 PFAM Glycosyl transferases group 1 K13057 - 2.4.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 607.0
HFD3_k127_1880149_1 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 291.0
HFD3_k127_1880149_2 Alginate export - - - 0.00000000000000000000000000000000000000000002161 168.0
HFD3_k127_1880149_3 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.0000000000000000000000000000000000000001486 157.0
HFD3_k127_1880149_4 helix_turn_helix, Arsenical Resistance Operon Repressor K21903 - - 0.000000000000000000000000000006548 123.0
HFD3_k127_1898322_0 General secretory system II, protein E domain protein K02652 - - 4.706e-233 734.0
HFD3_k127_1898322_1 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003658 570.0
HFD3_k127_1898322_2 Type II secretion system (T2SS), protein F K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 512.0
HFD3_k127_1898322_3 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 435.0
HFD3_k127_1898322_4 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 359.0
HFD3_k127_1898322_5 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004464 276.0
HFD3_k127_1898322_6 PFAM ATP-binding region, ATPase domain protein K02668,K07708,K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002491 289.0
HFD3_k127_1898322_7 regulatory protein GntR HTH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000137 239.0
HFD3_k127_1898322_8 metal-dependent phosphohydrolase HD region - - - 0.00000000000000000000000000000000000000000000000001301 196.0
HFD3_k127_1898322_9 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.0000000000000000000000000000000000000003894 165.0
HFD3_k127_1906214_0 PFAM Cys Met metabolism K01740 - 2.5.1.49 1.458e-216 679.0
HFD3_k127_1906214_1 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005334 328.0
HFD3_k127_1906214_2 Cytochrome C oxidase, cbb3-type, subunit III K08906 - - 0.000000000000000000000000000007043 119.0
HFD3_k127_1913781_0 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006938 426.0
HFD3_k127_1913781_1 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004917 435.0
HFD3_k127_1913781_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 413.0
HFD3_k127_1913781_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 316.0
HFD3_k127_1913781_4 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000004537 236.0
HFD3_k127_1913781_5 Biotin/lipoate A/B protein ligase family K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000002028 196.0
HFD3_k127_1913781_6 Oxidoreductase NAD-binding domain - - - 0.00000000000000000000000000000000000000002326 161.0
HFD3_k127_1913781_7 Cupredoxin-like domain K02275 - 1.9.3.1 0.000000000000000000000000000000005975 132.0
HFD3_k127_1913781_8 cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.0002792 51.0
HFD3_k127_1926950_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 7.369e-261 822.0
HFD3_k127_1926950_1 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 402.0
HFD3_k127_1926950_10 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.000000000000002767 77.0
HFD3_k127_1926950_11 DUF218 domain - - - 0.0000000000001796 82.0
HFD3_k127_1926950_12 Protein of unknown function (DUF3108) - - - 0.000000000008215 75.0
HFD3_k127_1926950_2 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002804 277.0
HFD3_k127_1926950_3 Formyl transferase K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000001271 259.0
HFD3_k127_1926950_4 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000001403 194.0
HFD3_k127_1926950_5 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000001115 168.0
HFD3_k127_1926950_6 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000005036 183.0
HFD3_k127_1926950_7 Domain of unknown function (DUF4416) - - - 0.00000000000000000000000000000000000000004233 166.0
HFD3_k127_1926950_8 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000005982 102.0
HFD3_k127_1926950_9 Trm112p-like protein K09791 - - 0.0000000000000001237 80.0
HFD3_k127_194631_0 Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004952 426.0
HFD3_k127_194631_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005416 349.0
HFD3_k127_194631_10 heat shock protein binding - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000004106 87.0
HFD3_k127_194631_12 Peptidase family M48 - - - 0.0000000002887 74.0
HFD3_k127_194631_2 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007762 311.0
HFD3_k127_194631_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 304.0
HFD3_k127_194631_4 Cytochrome c3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001961 289.0
HFD3_k127_194631_5 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000005433 234.0
HFD3_k127_194631_6 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000006149 206.0
HFD3_k127_194631_7 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000000000000000003661 120.0
HFD3_k127_194631_8 Protein involved in outer membrane biogenesis - - - 0.00000000000000000000009594 99.0
HFD3_k127_194631_9 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 - 1.16.3.1 0.000000000000000000003435 101.0
HFD3_k127_1971786_0 Pfam SNARE associated Golgi protein - - - 3.251e-249 790.0
HFD3_k127_1971786_1 Multicopper oxidase K06324 - 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 318.0
HFD3_k127_1971786_2 Endonuclease Exonuclease Phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000398 284.0
HFD3_k127_1971786_3 Helix-turn-helix domain - - - 0.0000000000000000000000000000000001673 139.0
HFD3_k127_1971786_4 lysine 2,3-aminomutase K01843 - 5.4.3.2 0.0000000008236 63.0
HFD3_k127_1974605_0 Protein of unknown function (DUF512) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 352.0
HFD3_k127_1974605_1 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 350.0
HFD3_k127_1974605_2 GTP-binding GTPase Middle Region K03665 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000391 289.0
HFD3_k127_1974605_3 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.000000000000000000000000000000000002587 140.0
HFD3_k127_1974605_4 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.00000000000000000000000000000000431 139.0
HFD3_k127_1990112_0 Type II secretion system (T2SS), protein F K12511 - - 0.000000000000000001052 99.0
HFD3_k127_1990112_1 Type II secretion system protein F domain-containing protein 1 K12510 - - 0.00000000000000000736 88.0
HFD3_k127_1990112_2 protein kinase activity - - - 0.00000001049 63.0
HFD3_k127_201286_0 Fructose-1,6-bisphosphatase K01622 - 3.1.3.11,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 567.0
HFD3_k127_201286_1 Male sterility protein K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008237 350.0
HFD3_k127_201286_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009911 312.0
HFD3_k127_201286_3 Phosphoglucose isomerase K01810,K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007829 289.0
HFD3_k127_201286_4 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000006325 216.0
HFD3_k127_201286_5 - - - - 0.00000009365 57.0
HFD3_k127_210966_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.257e-272 850.0
HFD3_k127_210966_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.312e-211 669.0
HFD3_k127_210966_10 Transcriptional regulator K13643 - - 0.0000000000000000000000000000000469 133.0
HFD3_k127_210966_11 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000001613 133.0
HFD3_k127_210966_12 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000002615 108.0
HFD3_k127_210966_13 YbbR-like protein - GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 - 0.0000000005713 68.0
HFD3_k127_210966_14 competence protein ComEA helix-hairpin-helix repeat protein K02237 - - 0.00001069 55.0
HFD3_k127_210966_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 572.0
HFD3_k127_210966_3 PFAM aspartate glutamate uridylate kinase K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 563.0
HFD3_k127_210966_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004039 441.0
HFD3_k127_210966_5 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 286.0
HFD3_k127_210966_6 Serine acetyltransferase, N-terminal K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 285.0
HFD3_k127_210966_7 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001558 281.0
HFD3_k127_210966_8 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000006254 204.0
HFD3_k127_210966_9 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000001092 158.0
HFD3_k127_2183353_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 6.685e-286 908.0
HFD3_k127_2183353_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 2.06e-198 631.0
HFD3_k127_2183353_10 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 381.0
HFD3_k127_2183353_11 PFAM aminotransferase class V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 378.0
HFD3_k127_2183353_12 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006484 387.0
HFD3_k127_2183353_13 Conserved protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 353.0
HFD3_k127_2183353_14 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006645 342.0
HFD3_k127_2183353_15 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 332.0
HFD3_k127_2183353_16 Lytic transglycosylase, SLT, LysM and LysM domain-containing K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 334.0
HFD3_k127_2183353_17 ATPase associated with various cellular K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 303.0
HFD3_k127_2183353_18 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003375 283.0
HFD3_k127_2183353_19 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005203 258.0
HFD3_k127_2183353_2 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 586.0
HFD3_k127_2183353_20 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003058 265.0
HFD3_k127_2183353_21 NAD dependent epimerase/dehydratase family K07535 - - 0.000000000000000000000000000000000000000000000000000000000000000000001108 250.0
HFD3_k127_2183353_22 Peptidase family S58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000006682 246.0
HFD3_k127_2183353_23 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000001916 244.0
HFD3_k127_2183353_24 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K13566 - 3.5.1.3 0.00000000000000000000000000000000000000000000000000000000001494 226.0
HFD3_k127_2183353_25 N,N-dimethylaniline monooxygenase activity K07222 - - 0.00000000000000000000000000000000000000000000000000003228 200.0
HFD3_k127_2183353_26 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000001201 213.0
HFD3_k127_2183353_27 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000168 181.0
HFD3_k127_2183353_28 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000005391 192.0
HFD3_k127_2183353_29 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000001138 178.0
HFD3_k127_2183353_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 590.0
HFD3_k127_2183353_30 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000009 164.0
HFD3_k127_2183353_31 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000189 167.0
HFD3_k127_2183353_32 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000002204 162.0
HFD3_k127_2183353_33 metallopeptidase activity K03630 - - 0.0000000000000000000000000000000000000001086 157.0
HFD3_k127_2183353_34 PBS lyase HEAT-like repeat - - - 0.0000000000000000000000000000000000000001653 168.0
HFD3_k127_2183353_35 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.00000000000000000000000000000000000003148 155.0
HFD3_k127_2183353_36 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000001495 147.0
HFD3_k127_2183353_37 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.00000000000000000000000000000000008192 141.0
HFD3_k127_2183353_38 Ribosomal L27 protein K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000513 132.0
HFD3_k127_2183353_39 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000001019 136.0
HFD3_k127_2183353_4 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 578.0
HFD3_k127_2183353_40 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000004838 135.0
HFD3_k127_2183353_41 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000001864 125.0
HFD3_k127_2183353_42 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000002702 123.0
HFD3_k127_2183353_43 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED K20866 - 3.1.3.10 0.000000000000000000000000000004167 139.0
HFD3_k127_2183353_44 Protein of unknown function DUF58 - - - 0.00000000000000000000000000005767 134.0
HFD3_k127_2183353_45 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000000000004664 129.0
HFD3_k127_2183353_46 Phosphoribosyl transferase domain - - - 0.000000000000000000000000009288 121.0
HFD3_k127_2183353_47 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000001355 113.0
HFD3_k127_2183353_48 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000002916 96.0
HFD3_k127_2183353_49 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000005524 93.0
HFD3_k127_2183353_5 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 545.0
HFD3_k127_2183353_50 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000508 89.0
HFD3_k127_2183353_51 - - - - 0.00000000000004481 75.0
HFD3_k127_2183353_52 MlaD protein K02067 - - 0.0000000000001542 72.0
HFD3_k127_2183353_53 Protein of unknown function (DUF3343) - - - 0.00000000001486 68.0
HFD3_k127_2183353_54 Modulates RecA activity K03565 GO:0003674,GO:0005488,GO:0005515,GO:0006282,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019219,GO:0019222,GO:0019899,GO:0030234,GO:0031323,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0048583,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0071496,GO:0080090,GO:0080134,GO:0080135,GO:0098772,GO:2001020 - 0.00000001067 63.0
HFD3_k127_2183353_55 Protein of unknown function (DUF721) - - - 0.00000001159 64.0
HFD3_k127_2183353_56 E-Z type HEAT repeats - - - 0.0004854 50.0
HFD3_k127_2183353_6 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008781 528.0
HFD3_k127_2183353_7 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005059 509.0
HFD3_k127_2183353_8 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006044 509.0
HFD3_k127_2183353_9 chelatase subunit ChlI K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006971 434.0
HFD3_k127_2296749_0 Carbamoyl-phosphate synthetase large chain domain protein K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 598.0
HFD3_k127_2296749_1 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000006534 132.0
HFD3_k127_2296749_2 Tetratricopeptide repeat - - - 0.000000000001493 80.0
HFD3_k127_2296749_3 Tetratricopeptide repeats - - - 0.00000008569 64.0
HFD3_k127_2308276_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 474.0
HFD3_k127_2308276_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 369.0
HFD3_k127_2308276_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000001531 218.0
HFD3_k127_2308276_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000001733 169.0
HFD3_k127_2308276_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000001563 142.0
HFD3_k127_2308276_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000553 110.0
HFD3_k127_2308276_6 Evidence 5 No homology to any previously reported sequences K08303 - - 0.000001903 55.0
HFD3_k127_2310274_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 3.837e-304 942.0
HFD3_k127_2310274_1 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 429.0
HFD3_k127_2310274_2 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 411.0
HFD3_k127_2310274_3 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 374.0
HFD3_k127_2310274_4 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007756 369.0
HFD3_k127_2310274_5 Extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 294.0
HFD3_k127_2310274_6 Peptidase family M23 K21471 - - 0.0000000000000000000000000000000000000000000001973 179.0
HFD3_k127_2310274_7 YtxH-like protein - - - 0.00000000000000000000002641 108.0
HFD3_k127_2310274_8 - - - - 0.000000000748 62.0
HFD3_k127_2339310_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 2.143e-240 754.0
HFD3_k127_2339310_1 Protein of unknown function (DUF1343) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 606.0
HFD3_k127_2339310_2 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000721 268.0
HFD3_k127_2339310_3 - - - - 0.000000000000000000000000000000000000000000001451 172.0
HFD3_k127_236559_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 1.664e-242 758.0
HFD3_k127_236559_1 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 7.595e-228 730.0
HFD3_k127_236559_10 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 339.0
HFD3_k127_236559_11 quinone binding K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000384 345.0
HFD3_k127_236559_12 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 330.0
HFD3_k127_236559_13 Dynamin family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006477 325.0
HFD3_k127_236559_14 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006836 317.0
HFD3_k127_236559_15 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009619 281.0
HFD3_k127_236559_16 NAD binding K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001853 266.0
HFD3_k127_236559_17 NapC/NirT cytochrome c family, N-terminal region K15876 - - 0.000000000000000000000000000000000000000000000000000000000000005087 222.0
HFD3_k127_236559_18 - - - - 0.0000000000000000000000000000000000000000000000000000000000005426 215.0
HFD3_k127_236559_19 response to oxidative stress K04063 - - 0.0000000000000000000000000000000000000000000000000000000000007143 213.0
HFD3_k127_236559_2 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 2.253e-221 695.0
HFD3_k127_236559_20 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000007074 197.0
HFD3_k127_236559_21 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000008521 180.0
HFD3_k127_236559_22 PFAM Protein-tyrosine phosphatase, low molecular weight K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000007658 173.0
HFD3_k127_236559_23 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000004169 177.0
HFD3_k127_236559_24 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000001086 157.0
HFD3_k127_236559_25 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000006047 146.0
HFD3_k127_236559_26 Smr domain - - - 0.0000000000000000000000000000007996 124.0
HFD3_k127_236559_27 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K01768,K07315 - 3.1.3.3,4.6.1.1 0.000000000000000000000000000001801 136.0
HFD3_k127_236559_28 - - - - 0.000000000000000000000000000005395 131.0
HFD3_k127_236559_29 Diguanylate cyclase - - - 0.00000000000000000000000000000569 133.0
HFD3_k127_236559_3 proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 9.714e-197 626.0
HFD3_k127_236559_30 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000004634 125.0
HFD3_k127_236559_31 membrane transporter protein K07090 - - 0.000000000000000000000000001465 117.0
HFD3_k127_236559_32 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000001332 108.0
HFD3_k127_236559_33 Rhomboid family - - - 0.0000000000000000000001777 111.0
HFD3_k127_236559_34 - - - - 0.00004835 51.0
HFD3_k127_236559_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00334,K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 515.0
HFD3_k127_236559_5 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007928 496.0
HFD3_k127_236559_6 Elongation factor SelB winged helix 3 K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 492.0
HFD3_k127_236559_7 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 461.0
HFD3_k127_236559_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 444.0
HFD3_k127_236559_9 formate dehydrogenase (NAD+) activity K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 417.0
HFD3_k127_2369142_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1062.0
HFD3_k127_2369142_1 Carbamoyl-phosphate synthetase large chain domain protein K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 584.0
HFD3_k127_2369142_10 surface antigen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006152 331.0
HFD3_k127_2369142_11 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 313.0
HFD3_k127_2369142_12 ABC transporter, ATP-binding protein K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001642 280.0
HFD3_k127_2369142_13 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006448,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072344,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112,GO:2000113,GO:2001124,GO:2001125 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001708 271.0
HFD3_k127_2369142_14 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002383 273.0
HFD3_k127_2369142_15 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000005461 254.0
HFD3_k127_2369142_16 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000002715 263.0
HFD3_k127_2369142_17 histidine kinase, HAMP - - - 0.000000000000000000000000000000000000000000000000000000000000001358 237.0
HFD3_k127_2369142_18 Belongs to the NadC ModD family K00767 GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000001038 242.0
HFD3_k127_2369142_19 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000000000000000000000000000000000000000004434 227.0
HFD3_k127_2369142_2 PKD domain K01179,K08651 - 3.2.1.4,3.4.21.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 586.0
HFD3_k127_2369142_20 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000001073 194.0
HFD3_k127_2369142_21 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000005964 205.0
HFD3_k127_2369142_22 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000007881 172.0
HFD3_k127_2369142_23 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000001102 186.0
HFD3_k127_2369142_24 PFAM Pilus assembly protein PilO K02664 - - 0.000000000000000000000000000000000000000003298 162.0
HFD3_k127_2369142_25 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000000000000000000005588 173.0
HFD3_k127_2369142_26 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000000000000000001081 150.0
HFD3_k127_2369142_27 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000001155 154.0
HFD3_k127_2369142_28 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000007052 140.0
HFD3_k127_2369142_29 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000003913 136.0
HFD3_k127_2369142_3 Aminotransferase K00812,K22457 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 484.0
HFD3_k127_2369142_30 response regulator - - - 0.000000000000000000000000000000000456 145.0
HFD3_k127_2369142_31 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000003894 132.0
HFD3_k127_2369142_32 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000003015 136.0
HFD3_k127_2369142_33 ATP-binding region ATPase domain protein, response regulator receiver, histidine kinase A domain protein - - - 0.0000000000000000000000001094 116.0
HFD3_k127_2369142_34 Pilus assembly protein, PilP K02665 - - 0.000000000000000000003563 100.0
HFD3_k127_2369142_35 Fimbrial assembly protein (PilN) K02663 - - 0.00000000000000000001896 99.0
HFD3_k127_2369142_36 Domain of unknown function (DUF1858) - - - 0.0000000000000000002499 89.0
HFD3_k127_2369142_37 PFAM helix-turn-helix domain protein - - - 0.00000000000000001726 86.0
HFD3_k127_2369142_38 Outer membrane efflux protein - - - 0.0000000000000001052 94.0
HFD3_k127_2369142_39 membrane protein domain - - - 0.0000000000006201 74.0
HFD3_k127_2369142_4 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 457.0
HFD3_k127_2369142_40 Tetratricopeptide repeats - - - 0.0000000004632 72.0
HFD3_k127_2369142_41 Roadblock/LC7 domain - - - 0.000005245 57.0
HFD3_k127_2369142_5 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009718 441.0
HFD3_k127_2369142_6 fructose-bisphosphate aldolase activity K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 407.0
HFD3_k127_2369142_7 type IV pilus secretin PilQ K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 430.0
HFD3_k127_2369142_8 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 403.0
HFD3_k127_2369142_9 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009163 323.0
HFD3_k127_2381808_0 bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 616.0
HFD3_k127_2381808_1 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008426 338.0
HFD3_k127_2381808_2 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 349.0
HFD3_k127_2381808_3 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 298.0
HFD3_k127_2381808_4 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004443 277.0
HFD3_k127_2381808_5 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0002798 43.0
HFD3_k127_2383449_0 Glycosyl hydrolase family 57 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005725 490.0
HFD3_k127_2383449_1 DNA polymerase alpha chain like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002301 256.0
HFD3_k127_2383449_2 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000001292 145.0
HFD3_k127_2383449_3 Protein conserved in bacteria - - - 0.000000000000002973 86.0
HFD3_k127_2391000_0 Heat shock 70 kDa protein K04043 - - 4.822e-281 875.0
HFD3_k127_2391000_1 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 372.0
HFD3_k127_2391000_2 Belongs to the ClpA ClpB family K03695,K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 334.0
HFD3_k127_2391000_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000001683 248.0
HFD3_k127_2391000_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000000001759 194.0
HFD3_k127_2391000_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000003318 160.0
HFD3_k127_240882_0 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 2.69e-199 627.0
HFD3_k127_240882_1 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006448 595.0
HFD3_k127_240882_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000003872 230.0
HFD3_k127_240882_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000005934 224.0
HFD3_k127_240882_12 ABC-type sugar transport system, periplasmic component K02027 - - 0.0000000000000000000000000000000000000000000000000000000000003045 215.0
HFD3_k127_240882_13 Protein of unknown function (DUF1499) - - - 0.00000000000000000000000000000000000000000000000000000001009 204.0
HFD3_k127_240882_14 - - - - 0.0000000000000000000000000000000000000000000000000000113 196.0
HFD3_k127_240882_15 LemA family K03744 - - 0.00000000000000000000000000000000000000000000001274 177.0
HFD3_k127_240882_16 - - - - 0.00000000000000000000000000000000000000000000004111 179.0
HFD3_k127_240882_17 Protein of unknown function (DUF1318) - - - 0.000000000000000000000000000000000000000000008659 171.0
HFD3_k127_240882_18 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10672,K21579 - 1.21.4.2,1.21.4.4 0.0000000000000000000000000000000004558 132.0
HFD3_k127_240882_19 In the first step of glycine, betaine and sarcosine reductases, the substrate is bound to component PB via a Schiff base intermediate. Then the PB-activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a carboxymethylated selenoether and the respective amine. By action of component PC, acetyl phosphate is formed, leaving component PA in its oxidized state. Finally component PA becomes reduced by the thioredoxin system to start a new catalytic cycle of reductive deamination K10670 - 1.21.4.2,1.21.4.3,1.21.4.4 0.00000000000000000000001447 103.0
HFD3_k127_240882_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K21577 - 1.21.4.2,1.21.4.3,1.21.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 537.0
HFD3_k127_240882_20 Thioredoxin - - - 0.00000000000000005698 85.0
HFD3_k127_240882_21 snoRNA binding - - - 0.00000001375 63.0
HFD3_k127_240882_22 Glycine reductase complex selenoprotein A K10670 - 1.21.4.2,1.21.4.3,1.21.4.4 0.0004828 44.0
HFD3_k127_240882_3 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 510.0
HFD3_k127_240882_4 PFAM Glycine sarcosine betaine reductase complex, protein B, alpha and beta subunits K10671 - 1.21.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007768 441.0
HFD3_k127_240882_5 Glycine reductase complex component B subunit gamma K10672 - 1.21.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008978 417.0
HFD3_k127_240882_6 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007379 379.0
HFD3_k127_240882_7 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 406.0
HFD3_k127_240882_8 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 382.0
HFD3_k127_240882_9 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 324.0
HFD3_k127_2436277_0 PFAM ribonuclease II K01147 - 3.1.13.1 5.422e-208 657.0
HFD3_k127_2436277_1 Domain of unknown function (DUF4070) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 523.0
HFD3_k127_2436277_2 glycosyltransferase 36 associated K00702,K13688 - 2.4.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 475.0
HFD3_k127_2436277_3 AsmA-like C-terminal region K07289 - - 0.00001781 51.0
HFD3_k127_2449865_0 TIGRFAM The (Largely Gram-negative Bacterial) Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 0.0 1688.0
HFD3_k127_2449865_1 Sugar (and other) transporter K03446 - - 1.103e-194 621.0
HFD3_k127_2449865_10 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.000000000000000000000000000000000000000000001553 169.0
HFD3_k127_2449865_11 lysyl-tRNA synthetase K04568 - - 0.00000000000000000000000000000000000022 147.0
HFD3_k127_2449865_12 phenylacetic acid degradation protein K02614 - - 0.00000000216 68.0
HFD3_k127_2449865_2 PFAM Outer membrane efflux protein K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 604.0
HFD3_k127_2449865_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 506.0
HFD3_k127_2449865_4 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007873 335.0
HFD3_k127_2449865_5 Major Facilitator Superfamily K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003781 321.0
HFD3_k127_2449865_6 PFAM Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005402 290.0
HFD3_k127_2449865_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009406 288.0
HFD3_k127_2449865_8 HlyD membrane-fusion protein of T1SS K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001484 284.0
HFD3_k127_2449865_9 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) - - - 0.000000000000000000000000000000000000000000000000000000006961 216.0
HFD3_k127_2453897_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 3.241e-270 844.0
HFD3_k127_2453897_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.919e-230 734.0
HFD3_k127_2453897_2 Acyl-CoA synthetase (NDP forming) K09181 - - 1.043e-205 665.0
HFD3_k127_2453897_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 473.0
HFD3_k127_2453897_4 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 406.0
HFD3_k127_2453897_5 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000001154 224.0
HFD3_k127_2453897_6 PFAM OmpA MotB domain protein K03640 - - 0.000000000000000000000000000000000004149 150.0
HFD3_k127_2453897_7 DRTGG domain protein K06873 - - 0.000000000000000000000000000000002732 138.0
HFD3_k127_2453897_8 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000001082 131.0
HFD3_k127_2580861_0 Major Facilitator Superfamily K02575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 503.0
HFD3_k127_2580861_1 COG1226 Kef-type K transport systems - - - 0.00000000000000000000000000000001612 139.0
HFD3_k127_2630510_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 3.775e-280 880.0
HFD3_k127_2630510_1 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 399.0
HFD3_k127_2630510_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000321 395.0
HFD3_k127_2630510_3 PFAM ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 358.0
HFD3_k127_2630510_4 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008861 241.0
HFD3_k127_2652057_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 336.0
HFD3_k127_2652057_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007997 307.0
HFD3_k127_2652057_2 Capsule synthesis protein K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006481 256.0
HFD3_k127_2652057_3 Alternative locus ID - - - 0.0000000000000000000000000000000000000000000000000000000000005735 226.0
HFD3_k127_2652057_4 PFAM amidohydrolase K20810 - 3.5.4.40 0.00000000000000000000000000000000000000000000000000000007836 212.0
HFD3_k127_2652057_5 LysM domain K01449,K19223 - 3.5.1.28 0.000000000000000000000000000000000000000000000000001624 194.0
HFD3_k127_2652057_6 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000001211 174.0
HFD3_k127_2652057_7 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000001418 158.0
HFD3_k127_2662475_0 associated with various cellular activities K03695,K03696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000507 554.0
HFD3_k127_2662475_1 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009448 499.0
HFD3_k127_2662475_10 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K02405 - - 0.0000000000000000000000000000000000000000000000000000000000002288 221.0
HFD3_k127_2662475_11 Thioesterase K18700 - 3.1.2.29 0.0000000000000000000000000000000000000000000000000303 189.0
HFD3_k127_2662475_12 ribosomal large subunit export from nucleus - - - 0.00000000000000000000000000000000000000000000000006862 183.0
HFD3_k127_2662475_13 RmuC family K09760 - - 0.00000000000000000000000000000000007401 148.0
HFD3_k127_2662475_14 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000001209 143.0
HFD3_k127_2662475_15 Zincin-like metallopeptidase - - - 0.0000000000000000000000000000000221 131.0
HFD3_k127_2662475_16 Glycosyl transferases group 1 K15521 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044249,GO:0044272,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 2.4.1.250 0.0000000000000000000000000000001053 139.0
HFD3_k127_2662475_2 phosphorelay signal transduction system K10941 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009403 425.0
HFD3_k127_2662475_3 PFAM Aminotransferase class I and II K11358 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 415.0
HFD3_k127_2662475_4 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009501 384.0
HFD3_k127_2662475_5 PFAM PfkB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 358.0
HFD3_k127_2662475_6 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005445 357.0
HFD3_k127_2662475_7 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000001096 280.0
HFD3_k127_2662475_8 HlyD family secretion protein K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006254 250.0
HFD3_k127_2662475_9 malic protein domain protein K00027,K00029 - 1.1.1.38,1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000002994 232.0
HFD3_k127_2676822_0 Ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007146 486.0
HFD3_k127_2676822_1 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000000004317 212.0
HFD3_k127_2676822_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000002734 207.0
HFD3_k127_2676822_3 nucleotide phosphatase activity, acting on free nucleotides K06928 - 3.6.1.15 0.0000000000000000000000000000000000005642 146.0
HFD3_k127_2676822_4 Redoxin - - - 0.00000000000000000000000000005579 116.0
HFD3_k127_2684038_0 PFAM PfkB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 368.0
HFD3_k127_2684038_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000000000000000000004846 128.0
HFD3_k127_2886335_0 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 4.047e-226 713.0
HFD3_k127_2886335_1 Belongs to the thiolase family K00626 - 2.3.1.9 3.079e-215 676.0
HFD3_k127_2886335_10 TIGRFAM LAO AO transport system ATPase K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 342.0
HFD3_k127_2886335_11 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 327.0
HFD3_k127_2886335_12 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006715 312.0
HFD3_k127_2886335_13 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000000000000000000000000006671 242.0
HFD3_k127_2886335_14 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000001347 199.0
HFD3_k127_2886335_15 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000000000000597 191.0
HFD3_k127_2886335_16 PFAM Pyruvate ketoisovalerate oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000000000007325 201.0
HFD3_k127_2886335_17 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000009163 200.0
HFD3_k127_2886335_18 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000001414 182.0
HFD3_k127_2886335_19 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000002355 169.0
HFD3_k127_2886335_2 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 486.0
HFD3_k127_2886335_20 Transcription regulator MerR DNA binding K21902 - - 0.000000000000000000000000000000000000001318 151.0
HFD3_k127_2886335_21 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.00000000000002501 84.0
HFD3_k127_2886335_22 Diguanylate cyclase - - - 0.0000000009051 72.0
HFD3_k127_2886335_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 455.0
HFD3_k127_2886335_4 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 448.0
HFD3_k127_2886335_5 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 432.0
HFD3_k127_2886335_6 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 389.0
HFD3_k127_2886335_7 Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 375.0
HFD3_k127_2886335_8 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 396.0
HFD3_k127_2886335_9 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 372.0
HFD3_k127_2896580_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 569.0
HFD3_k127_2896580_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 488.0
HFD3_k127_2896580_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004681 320.0
HFD3_k127_2915988_0 ATPase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 424.0
HFD3_k127_2915988_1 Type II secretion system (T2SS), protein F K12511 - - 0.0000000000000000001393 89.0
HFD3_k127_2915988_2 protein conserved in bacteria - - - 0.00001162 60.0
HFD3_k127_2915988_3 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0001326 51.0
HFD3_k127_2945184_0 AcrB/AcrD/AcrF family - - - 0.0 2002.0
HFD3_k127_2945184_1 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 584.0
HFD3_k127_2945184_10 MlaA lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000755 293.0
HFD3_k127_2945184_11 Trypsin-like serine protease K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 293.0
HFD3_k127_2945184_12 MlaC protein K07323 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000865 255.0
HFD3_k127_2945184_13 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000268 231.0
HFD3_k127_2945184_14 Glycogen debranching enzyme - - - 0.000000000000000000000000000000000009156 139.0
HFD3_k127_2945184_15 - - - - 0.000000000000000000000000000002068 126.0
HFD3_k127_2945184_16 AraC-like ligand binding domain - - - 0.0000000000000000000000001657 116.0
HFD3_k127_2945184_17 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000002892 108.0
HFD3_k127_2945184_18 peroxiredoxin activity K01607 - 4.1.1.44 0.000000000000148 73.0
HFD3_k127_2945184_19 MlaD protein K06192 - - 0.000000000405 62.0
HFD3_k127_2945184_2 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 584.0
HFD3_k127_2945184_20 Beta-lactamase superfamily domain - - - 0.0000001984 57.0
HFD3_k127_2945184_3 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006365 574.0
HFD3_k127_2945184_4 aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 542.0
HFD3_k127_2945184_5 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 528.0
HFD3_k127_2945184_6 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 488.0
HFD3_k127_2945184_7 COGs COG0767 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 425.0
HFD3_k127_2945184_8 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 395.0
HFD3_k127_2945184_9 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 389.0
HFD3_k127_3119280_0 4Fe-4S ferredoxin K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001455 285.0
HFD3_k127_3119280_1 Polysulfide reductase - - - 0.0000000000000000000000000000000000000000000000000004325 206.0
HFD3_k127_3119280_2 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.000000000000000000000000000000000000007633 159.0
HFD3_k127_3119280_3 Protein involved in formate dehydrogenase formation K02380 - - 0.00000000000000000000000000000000158 143.0
HFD3_k127_3119280_4 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.000000000000000001184 86.0
HFD3_k127_3131750_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009738 411.0
HFD3_k127_3131750_1 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009404 357.0
HFD3_k127_3131750_2 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006825 247.0
HFD3_k127_31373_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1076.0
HFD3_k127_31373_1 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 1.603e-296 917.0
HFD3_k127_31373_10 PCRF K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006629 399.0
HFD3_k127_31373_11 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009405 396.0
HFD3_k127_31373_12 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008717 393.0
HFD3_k127_31373_13 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 392.0
HFD3_k127_31373_14 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005868 345.0
HFD3_k127_31373_15 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 351.0
HFD3_k127_31373_16 Metal-dependent phosphohydrolase K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 325.0
HFD3_k127_31373_17 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 318.0
HFD3_k127_31373_18 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 327.0
HFD3_k127_31373_19 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 309.0
HFD3_k127_31373_2 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 3.743e-197 648.0
HFD3_k127_31373_20 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007526 307.0
HFD3_k127_31373_21 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 311.0
HFD3_k127_31373_22 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 296.0
HFD3_k127_31373_23 reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002952 280.0
HFD3_k127_31373_24 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001898 270.0
HFD3_k127_31373_25 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000136 267.0
HFD3_k127_31373_26 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001132 261.0
HFD3_k127_31373_27 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000007982 259.0
HFD3_k127_31373_28 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000000000000005363 236.0
HFD3_k127_31373_29 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000003029 211.0
HFD3_k127_31373_3 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 612.0
HFD3_k127_31373_30 ATP cone domain K07738 - - 0.000000000000000000000000000000000000000000000000000000002425 206.0
HFD3_k127_31373_31 Lumazine binding domain K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000004958 197.0
HFD3_k127_31373_32 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000733 199.0
HFD3_k127_31373_33 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000004076 174.0
HFD3_k127_31373_34 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000009739 183.0
HFD3_k127_31373_35 COG0698 Ribose 5-phosphate isomerase RpiB K01808 - 5.3.1.6 0.0000000000000000000000000000000000000004503 157.0
HFD3_k127_31373_36 Polynucleotide kinase 3 phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000008439 138.0
HFD3_k127_31373_37 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000004136 123.0
HFD3_k127_31373_38 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000002846 128.0
HFD3_k127_31373_39 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000006964 111.0
HFD3_k127_31373_4 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 597.0
HFD3_k127_31373_40 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000000000007601 102.0
HFD3_k127_31373_41 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000004336 96.0
HFD3_k127_31373_42 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000002253 74.0
HFD3_k127_31373_43 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000007038 72.0
HFD3_k127_31373_44 Phage integrase family K07358 - - 0.000000000004838 70.0
HFD3_k127_31373_45 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.000000003044 69.0
HFD3_k127_31373_47 Belongs to the skp family K06142 - - 0.00006939 56.0
HFD3_k127_31373_48 PFAM Tetratricopeptide repeat - - - 0.0001948 54.0
HFD3_k127_31373_5 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 580.0
HFD3_k127_31373_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 575.0
HFD3_k127_31373_7 PFAM Mo-co oxidoreductase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000978 524.0
HFD3_k127_31373_8 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 513.0
HFD3_k127_31373_9 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007947 515.0
HFD3_k127_3140241_0 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008576 541.0
HFD3_k127_3140241_1 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 287.0
HFD3_k127_3140241_2 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000245 194.0
HFD3_k127_3145604_0 PFAM Type II secretion system protein E K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004903 427.0
HFD3_k127_3145604_1 Pilus formation protein N terminal region K02280 - - 0.000000000000000000000000000000000000000000000000003801 196.0
HFD3_k127_3145604_2 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.00000000000000000003365 102.0
HFD3_k127_3145604_3 Type II secretion system (T2SS), protein F - - - 0.00000009415 61.0
HFD3_k127_3171146_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1227.0
HFD3_k127_3171146_1 Domain of unknown function (DUF4118) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 309.0
HFD3_k127_3171146_2 - - - - 0.00000000000000004565 89.0
HFD3_k127_3171146_3 - - - - 0.00000000000000639 75.0
HFD3_k127_3240707_0 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 520.0
HFD3_k127_3240707_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007294 388.0
HFD3_k127_3240707_2 denitrification pathway K02569,K15876 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 362.0
HFD3_k127_3240707_3 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006119 297.0
HFD3_k127_3240707_4 formate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000008731 256.0
HFD3_k127_3240707_5 PFAM Cytochrome b(N-terminal) b6 petB - - - 0.0000000000000000000000000000000000000000000000000000000000004355 222.0
HFD3_k127_3240707_6 Cytochrome b subunit of formate dehydrogenase-like protein - - - 0.000000000000000000000000000000000000000005145 166.0
HFD3_k127_3241842_0 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 498.0
HFD3_k127_3241842_1 Pfam Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003544 268.0
HFD3_k127_3241842_2 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000002473 137.0
HFD3_k127_3241842_3 Glutamine amidotransferases class-II K07008 - 3.5.1.118 0.00000000000008793 81.0
HFD3_k127_3270623_0 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 4.615e-247 779.0
HFD3_k127_3270623_1 BadF/BadG/BcrA/BcrD ATPase family - - - 3.705e-224 701.0
HFD3_k127_3270623_10 KR domain K00023,K00059 - 1.1.1.100,1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 376.0
HFD3_k127_3270623_11 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 379.0
HFD3_k127_3270623_12 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 301.0
HFD3_k127_3270623_13 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 292.0
HFD3_k127_3270623_14 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002901 263.0
HFD3_k127_3270623_15 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000000000002981 229.0
HFD3_k127_3270623_16 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000002664 218.0
HFD3_k127_3270623_17 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000003169 211.0
HFD3_k127_3270623_18 Thioesterase K01075,K07107,K12073 - 3.1.2.23,3.1.2.28 0.00000000000000000000000000000000000000000000009115 179.0
HFD3_k127_3270623_2 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 5.075e-221 707.0
HFD3_k127_3270623_3 Enoyl-CoA hydratase/isomerase K07539 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 1.107e-215 675.0
HFD3_k127_3270623_4 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 3.385e-211 678.0
HFD3_k127_3270623_5 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 541.0
HFD3_k127_3270623_6 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 478.0
HFD3_k127_3270623_7 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006863 446.0
HFD3_k127_3270623_8 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 401.0
HFD3_k127_3270623_9 Branched-chain amino acid transport system / permease component K01997,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 380.0
HFD3_k127_3273988_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 6.332e-209 662.0
HFD3_k127_3273988_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000002598 269.0
HFD3_k127_3273988_2 RNA-metabolising metallo-beta-lactamase K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000761 233.0
HFD3_k127_3273988_3 Cytochrome c oxidase subunit III K02276,K02299 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000003834 194.0
HFD3_k127_3273988_4 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.00000000000000000000000000000000000000000000000000005376 203.0
HFD3_k127_3273988_5 cytochrome oxidase assembly K02259 - - 0.000000000000000000000000007359 122.0
HFD3_k127_3273988_6 TIGRFAM Caa(3)-type oxidase, subunit IV K02277 - 1.9.3.1 0.00000008358 63.0
HFD3_k127_3298935_0 ATPase BadF BadG BcrA BcrD type - - - 1.995e-310 981.0
HFD3_k127_3298935_1 PFAM glycosyl transferase family 51 K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 574.0
HFD3_k127_3298935_10 PFAM ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001181 285.0
HFD3_k127_3298935_11 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000002562 220.0
HFD3_k127_3298935_12 Protein of unknown function (DUF2400) - - - 0.0000000000000000000000000000000000000000000000003244 194.0
HFD3_k127_3298935_13 Methylase involved in ubiquinone menaquinone K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000001428 196.0
HFD3_k127_3298935_14 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000001098 172.0
HFD3_k127_3298935_15 Histidine kinase - - - 0.000000000000000000000000000000000000003861 155.0
HFD3_k127_3298935_16 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.0000000000000000000000000000000000002132 149.0
HFD3_k127_3298935_17 SAM-dependent methyltransferase - - - 0.0000000000000000000000000000000001658 141.0
HFD3_k127_3298935_18 TIGRFAM MJ0042 family finger-like protein - - - 0.00000000000000000000000002232 123.0
HFD3_k127_3298935_19 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000001136 104.0
HFD3_k127_3298935_2 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 419.0
HFD3_k127_3298935_20 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000009124 82.0
HFD3_k127_3298935_21 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000363 75.0
HFD3_k127_3298935_22 Heat shock 70 kDa protein K04043 - - 0.00000000000005654 72.0
HFD3_k127_3298935_23 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117 - - 0.0000000000008209 72.0
HFD3_k127_3298935_25 Response regulator receiver - - - 0.00000002267 61.0
HFD3_k127_3298935_3 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005003 406.0
HFD3_k127_3298935_4 4 iron, 4 sulfur cluster binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 397.0
HFD3_k127_3298935_5 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K11645 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 347.0
HFD3_k127_3298935_6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 346.0
HFD3_k127_3298935_7 ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 318.0
HFD3_k127_3298935_8 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005778 321.0
HFD3_k127_3298935_9 3-dehydroquinate synthase (EC 4.6.1.3) K11646 - 1.4.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 305.0
HFD3_k127_3308280_0 PFAM Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 372.0
HFD3_k127_3308280_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 331.0
HFD3_k127_3308280_2 Protein of unknown function (DUF1499) - - - 0.000000000000000000000000000000000000000000000000000000000000001982 226.0
HFD3_k127_3431812_0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 1.833e-225 710.0
HFD3_k127_3431812_1 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 321.0
HFD3_k127_3431812_2 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000006605 102.0
HFD3_k127_3434743_0 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 0.0 1258.0
HFD3_k127_3434743_1 alpha amylase, catalytic region - - - 3.65e-219 690.0
HFD3_k127_3434743_2 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 396.0
HFD3_k127_3434743_3 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006731 353.0
HFD3_k127_3434743_4 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009975,GO:0016874,GO:0016886,GO:0044424,GO:0044464,GO:0140098 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 323.0
HFD3_k127_3434743_5 PFAM Phosphatidic acid phosphatase type 2 haloperoxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002234 287.0
HFD3_k127_3434743_6 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000008187 217.0
HFD3_k127_3434743_7 Heavy-metal resistance - - - 0.000000000000000000000000008176 116.0
HFD3_k127_3434743_8 Thioesterase-like superfamily K07107 - - 0.00000000000000000000006526 102.0
HFD3_k127_3434743_9 regulation of microtubule-based process K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.000000000002317 79.0
HFD3_k127_34723_0 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 1.73e-250 784.0
HFD3_k127_34723_1 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 612.0
HFD3_k127_34723_2 Glycosyl transferase, family 2 K11936 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 439.0
HFD3_k127_34723_3 PFAM Polysaccharide deacetylase K11931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004556 308.0
HFD3_k127_34723_4 Thioredoxin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000001857 218.0
HFD3_k127_34723_5 Biotin-requiring enzyme - - - 0.00000000000000000000000000009767 126.0
HFD3_k127_34723_6 Carboxyl transferase domain K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 0.000000000000000006205 83.0
HFD3_k127_34723_7 Tetratricopeptide repeat - - - 0.000000000008529 79.0
HFD3_k127_3498579_0 Enoyl-CoA hydratase/isomerase K14469 - 1.3.1.84,4.2.1.116,6.2.1.36 0.000000000000000000000000000001999 143.0
HFD3_k127_3498579_1 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000007602 114.0
HFD3_k127_3498579_2 Enoyl-CoA hydratase K15866 - 5.3.3.18 0.0000000000000141 90.0
HFD3_k127_3498579_3 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 0.000000000001966 83.0
HFD3_k127_3498579_4 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.000000000003403 82.0
HFD3_k127_3498953_0 Glycoprotease family K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 331.0
HFD3_k127_3498953_1 Large family of predicted nucleotide-binding domains K07175 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000318 257.0
HFD3_k127_3498953_2 Deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007075 248.0
HFD3_k127_3498953_3 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000000007638 173.0
HFD3_k127_3498953_4 - - - - 0.000000000000000000000000000001422 128.0
HFD3_k127_3520251_0 Pfam:DUF162 K18929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 357.0
HFD3_k127_3520251_1 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 347.0
HFD3_k127_3520251_2 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029,K10002 - - 0.00000000000000000000000000000000000000000000000004733 179.0
HFD3_k127_3520251_3 LUD domain K00782 - - 0.0000000000000000000000000000000003084 147.0
HFD3_k127_3524471_0 Molybdopterin oxidoreductase Fe4S4 domain K00370 - 1.7.5.1 0.0 1939.0
HFD3_k127_3524471_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1291.0
HFD3_k127_3524471_10 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000001255 123.0
HFD3_k127_3524471_11 Cytochrome c - - - 0.0000000000000000006433 93.0
HFD3_k127_3524471_12 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000001022 61.0
HFD3_k127_3524471_13 PFAM Uncharacterised protein family UPF0150 - - - 0.000000002439 60.0
HFD3_k127_3524471_2 Nitrate reductase, beta subunit K00371,K17051 - 1.7.5.1 9.951e-226 708.0
HFD3_k127_3524471_3 Transporter K02575 - - 1.068e-196 622.0
HFD3_k127_3524471_4 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03753,K13818 - 2.7.7.77 0.0000000000000000000000000000000000000000000000000000000000000000000000001428 250.0
HFD3_k127_3524471_5 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.000000000000000000000000000000000000000000000000000000000000000000000003053 254.0
HFD3_k127_3524471_6 nitrate reductase activity K00370,K00374,K02575 GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006950,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009628,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0036293,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0055114,GO:0070469,GO:0070470,GO:0070482,GO:0071944,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000004719 251.0
HFD3_k127_3524471_7 PFAM ATP-binding region, ATPase domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000009356 187.0
HFD3_k127_3524471_8 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000001375 141.0
HFD3_k127_3524471_9 Nitrate reductase delta subunit K00373 - - 0.0000000000000000000000000000000005227 137.0
HFD3_k127_3548169_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 505.0
HFD3_k127_3548169_1 Biotin-lipoyl like K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 411.0
HFD3_k127_3548169_2 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000637 299.0
HFD3_k127_3548169_3 PFAM outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006708 276.0
HFD3_k127_3579202_0 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 1.506e-243 758.0
HFD3_k127_3579202_1 malic protein domain protein K00027,K00029 - 1.1.1.38,1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 577.0
HFD3_k127_3579202_2 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000005501 210.0
HFD3_k127_3579202_3 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000000000003813 197.0
HFD3_k127_3579202_4 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000001387 160.0
HFD3_k127_3579202_5 TPM domain K06872 - - 0.0000000000000000000000000000000001873 142.0
HFD3_k127_3579202_6 inositol-3-phosphate synthase activity K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.000000000000000000000002865 110.0
HFD3_k127_3579202_7 nucleotidyltransferase activity - - - 0.0000000000000000000000083 110.0
HFD3_k127_3579202_8 RNA-binding protein containing a PIN domain - - - 0.0000000001656 70.0
HFD3_k127_3652483_0 Large extracellular alpha-helical protein K06894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 520.0
HFD3_k127_3652483_1 NAD(P)H-binding K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005303 308.0
HFD3_k127_3652483_2 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000004818 252.0
HFD3_k127_3652483_3 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000009558 73.0
HFD3_k127_3652483_4 Putative regulatory protein - - - 0.00000000001245 66.0
HFD3_k127_3652483_5 Extracellular repeat protein, HAF family - - - 0.0000003296 62.0
HFD3_k127_3659837_0 Elongation factor Tu GTP binding domain K00956 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 613.0
HFD3_k127_3659837_1 Beta-eliminating lyase K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000613 613.0
HFD3_k127_3659837_10 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006667 341.0
HFD3_k127_3659837_11 unfolded protein binding K04083 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0006979,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0031647,GO:0036506,GO:0042026,GO:0042802,GO:0043167,GO:0043169,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0065007,GO:0065008 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 335.0
HFD3_k127_3659837_12 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 300.0
HFD3_k127_3659837_13 PFAM regulatory protein, ArsR - - - 0.0000000000000000000000000000000000006682 142.0
HFD3_k127_3659837_14 PIN domain - - - 0.000000000000000000000000001447 118.0
HFD3_k127_3659837_15 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000001722 64.0
HFD3_k127_3659837_17 Uncharacterized small protein (DUF2292) - - - 0.0000005219 53.0
HFD3_k127_3659837_18 Transcriptional regulator, AbrB family - - - 0.00002568 49.0
HFD3_k127_3659837_2 Pfam Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 544.0
HFD3_k127_3659837_3 Sulfate ABC transporter, periplasmic sulfate-binding protein K02048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 515.0
HFD3_k127_3659837_4 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 521.0
HFD3_k127_3659837_5 TIGRFAM sulfate adenylyltransferase, small subunit K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 440.0
HFD3_k127_3659837_6 Binding-protein-dependent transport system inner membrane component K02047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 435.0
HFD3_k127_3659837_7 Binding-protein-dependent transport system inner membrane component K02046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005279 405.0
HFD3_k127_3659837_8 Phosphate-selective porin O and P K07221 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 363.0
HFD3_k127_3659837_9 uridine phosphorylase activity K00757 - 2.4.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 338.0
HFD3_k127_3667590_0 Chase2 domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 349.0
HFD3_k127_3667590_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 308.0
HFD3_k127_3667590_2 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000006498 247.0
HFD3_k127_3667590_3 - - - - 0.0000000000000000000000000000000008945 137.0
HFD3_k127_3667590_4 - - - - 0.0000000000000009364 81.0
HFD3_k127_3667590_5 Tetratricopeptide repeat - - - 0.000002638 59.0
HFD3_k127_3750142_0 ATP-binding region, ATPase domain protein domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 351.0
HFD3_k127_3750142_1 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 340.0
HFD3_k127_3750142_2 - - - - 0.0000000000000000000000000000000000000000000000000003572 192.0
HFD3_k127_3750142_3 transcription factor binding - - - 0.0000000000000000000000000002713 117.0
HFD3_k127_3750142_4 1,4-alpha-glucan branching enzyme K00700 - 2.4.1.18 0.00000003487 59.0
HFD3_k127_377383_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.13e-223 719.0
HFD3_k127_377383_1 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 455.0
HFD3_k127_377383_2 TIGRFAM DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000005197 236.0
HFD3_k127_377383_3 Type IV pilin PilA K02650 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.000000000000000000000003116 107.0
HFD3_k127_377383_4 LysM domain - - - 0.0000000000000000000000601 110.0
HFD3_k127_377383_5 Type IV pilin PilA K02650 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.00000000000000000007148 96.0
HFD3_k127_378581_0 Glycosyltransferase family 20 K00697,K13057,K20436 - 2.4.1.15,2.4.1.245,2.4.1.347,2.5.1.135 0.0 1067.0
HFD3_k127_378581_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 463.0
HFD3_k127_378581_2 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 451.0
HFD3_k127_378581_3 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000001611 166.0
HFD3_k127_378581_4 Rubrerythrin - - - 0.00003115 53.0
HFD3_k127_38585_0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit - - - 1.518e-222 714.0
HFD3_k127_38585_1 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 611.0
HFD3_k127_38585_10 AAA domain K07321 - - 0.00000000000000000000000000000000000000000000000005414 201.0
HFD3_k127_38585_11 PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000003116 174.0
HFD3_k127_38585_12 PFAM LmbE family protein K18455 - 3.5.1.115 0.00000000000000000000000000000000000177 155.0
HFD3_k127_38585_13 Belongs to the 'phage' integrase family - - - 0.000006622 55.0
HFD3_k127_38585_2 Ammonium Transporter Family K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 580.0
HFD3_k127_38585_3 CO dehydrogenase/acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 404.0
HFD3_k127_38585_4 PFAM ferredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 370.0
HFD3_k127_38585_5 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005528 345.0
HFD3_k127_38585_6 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 309.0
HFD3_k127_38585_7 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000308 252.0
HFD3_k127_38585_8 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000002006 232.0
HFD3_k127_38585_9 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000001961 206.0
HFD3_k127_3887435_0 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 525.0
HFD3_k127_3887435_1 HlyD family secretion protein K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000568 509.0
HFD3_k127_3887435_2 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 452.0
HFD3_k127_3887435_3 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 397.0
HFD3_k127_3887435_4 UPF0126 domain - - - 0.00000000000000000000000000000000000000000000000001485 186.0
HFD3_k127_3887435_5 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0000000000001547 70.0
HFD3_k127_3893739_0 Extracellular solute-binding protein K02027 - - 1.88e-209 661.0
HFD3_k127_3893739_1 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 434.0
HFD3_k127_3893739_2 ABC-type sugar transport system, permease component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 412.0
HFD3_k127_3893739_3 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 403.0
HFD3_k127_3893739_4 ADP-ribosylglycohydrolase K05521 - 3.2.2.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 344.0
HFD3_k127_3893739_5 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) K05951 - 2.4.2.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 291.0
HFD3_k127_3893739_6 - - - - 0.000000000005048 73.0
HFD3_k127_3897469_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005852 592.0
HFD3_k127_3897469_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 594.0
HFD3_k127_3897469_10 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000004437 115.0
HFD3_k127_3897469_11 Regulatory protein, FmdB family - - - 0.000000000000000002437 90.0
HFD3_k127_3897469_12 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000007687 87.0
HFD3_k127_3897469_13 energy transducer activity K03832 - - 0.000000000000008766 85.0
HFD3_k127_3897469_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 418.0
HFD3_k127_3897469_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 367.0
HFD3_k127_3897469_4 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 301.0
HFD3_k127_3897469_5 PFAM Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001027 237.0
HFD3_k127_3897469_6 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000002216 243.0
HFD3_k127_3897469_7 HD domain - - - 0.0000000000000000000000000000000000000000000001668 194.0
HFD3_k127_3897469_8 Universal stress protein K06149 - - 0.000000000000000000000000000000000003695 142.0
HFD3_k127_3897469_9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000008655 119.0
HFD3_k127_3927071_0 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 313.0
HFD3_k127_3927071_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 289.0
HFD3_k127_3927071_2 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000002499 118.0
HFD3_k127_3944028_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009841 484.0
HFD3_k127_3944028_1 phosphatidate phosphatase activity K19302 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009605,GO:0009607,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0042578,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0046467,GO:0046493,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0071704,GO:0075136,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.27 0.0000000000000000000000000000000001519 137.0
HFD3_k127_3944028_2 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.000000000000000000000000000005648 120.0
HFD3_k127_3945460_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.296e-238 752.0
HFD3_k127_3945460_1 thiamine pyrophosphate protein TPP binding domain protein K01652 - 2.2.1.6 3.567e-230 751.0
HFD3_k127_3945460_10 Protein of unknown function (DUF465) K09794 - - 0.00000001502 58.0
HFD3_k127_3945460_12 sequence-specific DNA binding - - - 0.000026 53.0
HFD3_k127_3945460_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007911 610.0
HFD3_k127_3945460_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 500.0
HFD3_k127_3945460_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000462 287.0
HFD3_k127_3945460_5 TIGRFAM acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000001978 227.0
HFD3_k127_3945460_6 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000008533 202.0
HFD3_k127_3945460_7 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000003268 176.0
HFD3_k127_3945460_8 PFAM IS1 transposase - - - 0.0000000000000000000000000000000000000000004477 160.0
HFD3_k127_3945460_9 - - - - 0.00000000000000001564 84.0
HFD3_k127_3946915_0 PFAM Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005092 368.0
HFD3_k127_3946915_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000002825 265.0
HFD3_k127_3946915_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000009839 48.0
HFD3_k127_3991823_0 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 514.0
HFD3_k127_3991823_1 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 387.0
HFD3_k127_3991823_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 288.0
HFD3_k127_3991823_3 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006452 281.0
HFD3_k127_3991823_4 glycosyl transferase family 8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009619 281.0
HFD3_k127_3991823_5 Glycosyl transferase family 2 K00786 - - 0.0000000000000000000000000000000000000000000000000000000004248 208.0
HFD3_k127_3991823_6 Uncharacterized conserved protein (DUF2304) K09153 - - 0.0000000000000004544 88.0
HFD3_k127_4017619_0 FtsX-like permease family K02004 - - 1.188e-285 898.0
HFD3_k127_4017619_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004787 482.0
HFD3_k127_4017619_10 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000000000000000000000000000000000000002198 208.0
HFD3_k127_4017619_11 Domain of unknown function (DUF1848) - - - 0.0000000000000000000000000000000000000000000000000000009906 201.0
HFD3_k127_4017619_12 TraB family K09973 - - 0.0000000000000000000000000000000000000000000002042 181.0
HFD3_k127_4017619_13 Domain of unknown function (DUF4810) - - - 0.0000000000000000000000000000003459 126.0
HFD3_k127_4017619_14 PFAM Cold-shock protein, DNA-binding K03704 - - 0.00000000000000000000000000002424 117.0
HFD3_k127_4017619_15 Preprotein translocase SecG subunit K03075 - - 0.0000000000000000000000002274 109.0
HFD3_k127_4017619_16 - - - - 0.00000000000000000000489 105.0
HFD3_k127_4017619_17 Late embryogenesis abundant protein - - - 0.000005968 55.0
HFD3_k127_4017619_2 FAD dependent oxidoreductase K07137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005121 441.0
HFD3_k127_4017619_3 Curli production assembly/transport component CsgG - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006584 404.0
HFD3_k127_4017619_4 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007666 373.0
HFD3_k127_4017619_5 PFAM ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 363.0
HFD3_k127_4017619_6 nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 304.0
HFD3_k127_4017619_7 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 299.0
HFD3_k127_4017619_8 D-isomer specific 2-hydroxyacid dehydrogenase K00015,K00090 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0016618,GO:0030267,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 300.0
HFD3_k127_4017619_9 Putative bacterial lipoprotein (DUF799) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001415 263.0
HFD3_k127_40306_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298 - 1.10.3.10,1.9.3.1 2.929e-214 678.0
HFD3_k127_40306_1 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004992 568.0
HFD3_k127_40306_10 Major Facilitator Superfamily K08177 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008288 291.0
HFD3_k127_40306_11 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005455 278.0
HFD3_k127_40306_12 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002486 263.0
HFD3_k127_40306_13 AAA domain, putative AbiEii toxin, Type IV TA system K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006191 261.0
HFD3_k127_40306_14 - - - - 0.00000000000000000000000000000000000000000000000000000000007873 213.0
HFD3_k127_40306_15 PFAM secretion protein HlyD family protein K01993,K02005 - - 0.000000000000000000000000000000000000000000000000000000004385 201.0
HFD3_k127_40306_16 signal sequence binding K07152 - - 0.00000000000000000000000000000000000000000000000000000001094 209.0
HFD3_k127_40306_17 Cytochrome c oxidase subunit III K02276,K02299 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000005637 202.0
HFD3_k127_40306_18 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000000001423 198.0
HFD3_k127_40306_19 intermembrane phospholipid transfer K07323 - - 0.00000000000000000000000000000000000000000000000000004444 194.0
HFD3_k127_40306_2 Apoptosis-inducing factor, mitochondrion-associated, C-term - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 536.0
HFD3_k127_40306_20 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000003944 178.0
HFD3_k127_40306_21 PFAM Mammalian cell entry related domain protein K02067 - - 0.00000000000000000000000000000000000000000009757 175.0
HFD3_k127_40306_22 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0048033,GO:0048034,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000000000000000000000000000008324 168.0
HFD3_k127_40306_23 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000171 147.0
HFD3_k127_40306_24 PFAM Cyclic nucleotide-binding K10914,K21563 - - 0.00000000000000000000000000001702 126.0
HFD3_k127_40306_25 Cytochrome oxidase assembly protein K02259 - - 0.00000000000000000000000003326 121.0
HFD3_k127_40306_26 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.0000000000000000000001102 105.0
HFD3_k127_40306_27 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000002315 104.0
HFD3_k127_40306_28 PFAM VacJ family lipoprotein K04754 - - 0.0000000000000000001971 93.0
HFD3_k127_40306_29 oxidase, subunit IV K02277 - 1.9.3.1 0.000000000000000000791 89.0
HFD3_k127_40306_3 RNA-metabolising metallo-beta-lactamase K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 520.0
HFD3_k127_40306_30 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K13810 - 2.2.1.2,5.3.1.9 0.0000000002787 67.0
HFD3_k127_40306_4 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000743 488.0
HFD3_k127_40306_5 Outer membrane efflux protein K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007491 459.0
HFD3_k127_40306_6 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 379.0
HFD3_k127_40306_7 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 323.0
HFD3_k127_40306_8 GTP cyclohydrolase I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 295.0
HFD3_k127_40306_9 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 286.0
HFD3_k127_4033037_0 Cytochrome c554 and c-prime - - - 2.118e-242 757.0
HFD3_k127_4033037_1 Protein of unknown function (DUF3373) - - - 0.00000000000000000000000000000000000000000000000000000314 192.0
HFD3_k127_4033037_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000001594 84.0
HFD3_k127_4065271_0 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007207 368.0
HFD3_k127_4065271_1 Periplasmic binding protein K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005824 336.0
HFD3_k127_4065271_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000876 147.0
HFD3_k127_4103813_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003444 267.0
HFD3_k127_4103813_1 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000001854 199.0
HFD3_k127_4103813_2 Rod shape-determining protein K03569 - - 0.000000000000000000000000000000000000000002427 157.0
HFD3_k127_4103813_3 nucleic acid binding K01174 - 3.1.31.1 0.0000000000000000000000004736 117.0
HFD3_k127_4117343_0 Fumarate reductase flavoprotein C-term K00239,K00244,K00278 GO:0000104,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0022900,GO:0032991,GO:0044237,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803 1.3.5.1,1.3.5.4,1.4.3.16 3.727e-259 810.0
HFD3_k127_4117343_1 Belongs to the peptidase S16 family - - - 5.742e-229 734.0
HFD3_k127_4117343_10 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009637 370.0
HFD3_k127_4117343_11 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671,K22345 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9,4.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 369.0
HFD3_k127_4117343_12 Succinate dehydrogenase fumarate reductase K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008572 348.0
HFD3_k127_4117343_13 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 360.0
HFD3_k127_4117343_14 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007973 337.0
HFD3_k127_4117343_15 NUDIX domain K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 325.0
HFD3_k127_4117343_16 branched-chain amino acid transmembrane transporter activity K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 312.0
HFD3_k127_4117343_17 PFAM ABC transporter related K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 323.0
HFD3_k127_4117343_18 oxidase, subunit K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006268 289.0
HFD3_k127_4117343_19 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001046 283.0
HFD3_k127_4117343_2 PFAM Xanthine uracil vitamin C permease K06901 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 600.0
HFD3_k127_4117343_20 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001316 265.0
HFD3_k127_4117343_21 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000001349 251.0
HFD3_k127_4117343_22 Pfam Enoyl-CoA hydratase isomerase K13816 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001697 254.0
HFD3_k127_4117343_23 PFAM LmbE family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000003839 241.0
HFD3_k127_4117343_24 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000009218 214.0
HFD3_k127_4117343_25 Ferritin-like domain K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000001621 215.0
HFD3_k127_4117343_26 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.00000000000000000000000000000000000000000008833 163.0
HFD3_k127_4117343_27 Cache_2 - - - 0.000000000000000000000000000000000000001462 153.0
HFD3_k127_4117343_28 WYL domain K13573 - - 0.000000000000000000000000000000000164 148.0
HFD3_k127_4117343_29 Rhodanese Homology Domain - - - 0.00000000000000000000000000002248 124.0
HFD3_k127_4117343_3 Histidine kinase K10715,K20974 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 595.0
HFD3_k127_4117343_30 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane K00247 - - 0.0000000000000000000000000001726 117.0
HFD3_k127_4117343_31 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000000000000000000002812 116.0
HFD3_k127_4117343_32 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane K00246 - - 0.00000000000000000000000001176 114.0
HFD3_k127_4117343_33 response regulator, receiver K07814 - - 0.0000000489 56.0
HFD3_k127_4117343_34 Domain of unknown function (DUF4282) - - - 0.000002579 57.0
HFD3_k127_4117343_4 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 563.0
HFD3_k127_4117343_5 Cytochrome bd-type quinol oxidase subunit 1 K00425 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004777 507.0
HFD3_k127_4117343_6 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 489.0
HFD3_k127_4117343_7 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 451.0
HFD3_k127_4117343_8 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 437.0
HFD3_k127_4117343_9 nuclear chromosome segregation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 399.0
HFD3_k127_4144216_0 biotin synthase activity K03150 GO:0003674,GO:0003824,GO:0005488,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0036355,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 443.0
HFD3_k127_4144216_1 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000003637 261.0
HFD3_k127_4144216_2 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000009859 248.0
HFD3_k127_4144216_3 PDGLE domain K02007 - - 0.00000000000000000000000000000000000000000000000000519 187.0
HFD3_k127_4150542_0 MMPL family K07003 - - 0.0 1115.0
HFD3_k127_4150542_1 Protein of unknown function (DUF1302) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 306.0
HFD3_k127_4150542_2 Photosynthesis system II assembly factor YCF48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004968 299.0
HFD3_k127_4162544_0 ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 329.0
HFD3_k127_4162544_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 335.0
HFD3_k127_4162544_2 PFAM ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 289.0
HFD3_k127_4162544_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003403 268.0
HFD3_k127_4180428_0 Domain of unknown function(DUF2779) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 522.0
HFD3_k127_4180428_1 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002768 269.0
HFD3_k127_4194242_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 444.0
HFD3_k127_4194242_1 surface antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009009 325.0
HFD3_k127_4194242_2 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000005542 211.0
HFD3_k127_4194242_3 cheY-homologous receiver domain - - - 0.0000000000000000000000001035 114.0
HFD3_k127_4194242_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000004652 110.0
HFD3_k127_4194242_5 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000006429 77.0
HFD3_k127_4194848_0 PFAM Aldo keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005113 443.0
HFD3_k127_4194848_1 Acetyltransferase (GNAT) domain - - - 0.00000000000002666 79.0
HFD3_k127_4194848_2 YceI-like domain - - - 0.0000004117 59.0
HFD3_k127_4248307_0 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282,K18008 - 1.12.2.1,1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 332.0
HFD3_k127_4248307_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00437,K00533 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.12.2.1,1.12.7.2 0.0000000000000000000000000000000000000000000002312 186.0
HFD3_k127_4248307_2 Hydrogenase accessory protein HypB K03189,K04652 - - 0.000000000000000000000000000000000000000000001621 169.0
HFD3_k127_4248307_3 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000004505 90.0
HFD3_k127_4313213_0 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 447.0
HFD3_k127_4313213_1 Belongs to the class I fructose-bisphosphate aldolase family K01623 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009769 445.0
HFD3_k127_4313213_10 Cytochrome oxidase maturation protein - - - 0.000000005044 58.0
HFD3_k127_4313213_2 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 438.0
HFD3_k127_4313213_3 Zinc-binding dehydrogenase K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003386 280.0
HFD3_k127_4313213_4 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003067 251.0
HFD3_k127_4313213_5 Heavy metal translocating P-type atpase K01533,K17686 - 3.6.3.4,3.6.3.54 0.00000000000000000000000000000000000000000000000000202 188.0
HFD3_k127_4313213_6 17 kDa outer membrane surface antigen - - - 0.00000000000000000000000000000000000000000000000000861 184.0
HFD3_k127_4313213_7 pyrroloquinoline quinone binding - - - 0.0000000000000000000000000000004652 130.0
HFD3_k127_4313213_8 - - - - 0.000000000000008892 77.0
HFD3_k127_4313213_9 OsmC-like protein - - - 0.0000000001102 65.0
HFD3_k127_4338525_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 8.496e-240 755.0
HFD3_k127_4338525_1 Hydrogenase expression formation protein (HypE) K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 346.0
HFD3_k127_4338525_2 Protein of unknown function (DUF1343) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 327.0
HFD3_k127_4338525_3 - - - - 0.0000000000000000000000000000000000000000000000007828 180.0
HFD3_k127_4388488_0 Elongation factor Tu domain 2 K02355 - - 1.912e-239 759.0
HFD3_k127_4388488_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 554.0
HFD3_k127_4388488_10 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000000000004047 261.0
HFD3_k127_4388488_11 ThiF family K03148,K21147 - 2.7.7.73,2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000003684 272.0
HFD3_k127_4388488_12 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002198 255.0
HFD3_k127_4388488_13 Transcriptional regulator, CarD family K07736 - - 0.0000000000000000000000000000000000000000000000000001033 196.0
HFD3_k127_4388488_14 TIGRFAM molybdenum cofactor synthesis domain - - - 0.0000000000000000000000000000000000000000000000000005984 190.0
HFD3_k127_4388488_15 MOSC domain - - - 0.00000000000000000000000000000000000000000000000002721 191.0
HFD3_k127_4388488_16 PBS lyase HEAT-like repeat - - - 0.0000000000000000000000000004407 134.0
HFD3_k127_4388488_17 phosphorelay signal transduction system - - - 0.000000000000000000008441 101.0
HFD3_k127_4388488_18 PFAM GGDEF domain containing protein - - - 0.00000005851 65.0
HFD3_k127_4388488_19 SMART Tetratricopeptide repeat - - - 0.00000939 58.0
HFD3_k127_4388488_2 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 372.0
HFD3_k127_4388488_3 metal-dependent phosphohydrolase HD region K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 361.0
HFD3_k127_4388488_4 Thiamine biosynthesis protein (ThiI) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 353.0
HFD3_k127_4388488_5 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 340.0
HFD3_k127_4388488_6 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 325.0
HFD3_k127_4388488_7 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 332.0
HFD3_k127_4388488_8 PFAM asparagine synthase K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 315.0
HFD3_k127_4388488_9 PFAM BadF BadG BcrA BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001143 268.0
HFD3_k127_4421844_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 7e-323 997.0
HFD3_k127_4421844_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 4.891e-310 979.0
HFD3_k127_4421844_2 HlyD family secretion protein K07798,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 359.0
HFD3_k127_4421844_3 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000001256 224.0
HFD3_k127_4482983_0 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000001928 160.0
HFD3_k127_4482983_1 VIT family - - - 0.00000000000000000000000000000009122 126.0
HFD3_k127_4482983_2 oxidase, subunit K00426 - 1.10.3.14 0.00000000000000000000000000284 116.0
HFD3_k127_4615246_0 Receptor family ligand binding region K01999 - - 4.961e-208 654.0
HFD3_k127_4615246_1 PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal K14534 - 4.2.1.120,5.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 564.0
HFD3_k127_4615246_10 PFAM short-chain dehydrogenase reductase SDR K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000004716 238.0
HFD3_k127_4615246_11 Iron-containing alcohol dehydrogenase - - - 0.00000000001028 69.0
HFD3_k127_4615246_2 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 424.0
HFD3_k127_4615246_3 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 373.0
HFD3_k127_4615246_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 378.0
HFD3_k127_4615246_5 Extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 355.0
HFD3_k127_4615246_6 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 355.0
HFD3_k127_4615246_7 PFAM 4-hydroxyphenylacetate 3-hydroxylase K00483,K21726 - 1.14.13.166,1.14.13.29,1.14.14.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007147 310.0
HFD3_k127_4615246_8 Amino acid amide ABC transporter ATP-binding protein 2, HAAT family K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 293.0
HFD3_k127_4615246_9 amino acid K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007533 290.0
HFD3_k127_4638086_0 TIGRFAM iron-sulfur cluster binding protein K18929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006661 456.0
HFD3_k127_4638086_1 PFAM NAD-dependent epimerase dehydratase K01784,K02473 - 5.1.3.2,5.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009941 404.0
HFD3_k127_4638086_2 Phosphoadenosine phosphosulfate reductase family K21947 - 2.8.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003704 323.0
HFD3_k127_4638086_3 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003327 278.0
HFD3_k127_4638086_4 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 - 2.1.1.219,2.1.1.220 0.000000000000000000000000000000000000000000000000000000000000000000000000000003624 269.0
HFD3_k127_4638086_5 Transposase IS200 like - - - 0.000000000000000000000000000000000000000006176 167.0
HFD3_k127_4638086_6 Cysteine-rich domain K18928 - - 0.00000000000000000000000000000000000000006405 154.0
HFD3_k127_4638086_7 PFAM Uncharacterised ACR, YkgG family COG1556 K00782 - - 0.00000000000008932 81.0
HFD3_k127_4638086_8 thiamine diphosphate biosynthetic process K03154 - - 0.0000000004914 62.0
HFD3_k127_4638086_9 Cytochrome c - - - 0.0001267 49.0
HFD3_k127_4666662_0 TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter K01537 - 3.6.3.8 1.435e-250 782.0
HFD3_k127_4666662_1 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 312.0
HFD3_k127_4666662_2 Tetratricopeptide repeat - - - 0.000000000000000000232 91.0
HFD3_k127_4667003_0 PFAM type II secretion system protein E K02283,K03609 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009712 572.0
HFD3_k127_4667003_1 Pilus formation protein N terminal region K02280 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002259 276.0
HFD3_k127_4667003_2 Flp pilus polar localization response receiver ATPase TadZ, FlhG domain-containing K02282 - - 0.0000000000000000000000000000000000000000000000000000000004852 217.0
HFD3_k127_4667003_3 Flp pilus assembly protein CpaB K02279 - - 0.0000000000000000000000000000000000000193 155.0
HFD3_k127_4667003_4 Putative Flp pilus-assembly TadE/G-like - - - 0.000000000000000000000000000000004016 142.0
HFD3_k127_4667003_5 TadE-like protein - - - 0.0000000000837 68.0
HFD3_k127_4667003_6 Flp/Fap pilin component K02651 - - 0.000003462 50.0
HFD3_k127_4680807_0 Amino acid permease - - - 8.446e-201 647.0
HFD3_k127_4680807_1 Belongs to the DegT DnrJ EryC1 family K13017 - 2.6.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 426.0
HFD3_k127_4680807_10 Glycosyltransferase family 10 (fucosyltransferase) C-term K20151 - 2.4.1.152,2.4.1.65 0.00000000000000000000000000000000000000000000000000000000000000000006526 243.0
HFD3_k127_4680807_11 Glycosyl transferase, family 9 K02841,K02843,K02847,K02849,K21003 - - 0.0000000000000000000000000000000000000000000000000000000000000002556 233.0
HFD3_k127_4680807_12 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.000000000000000000000000000000000000000000000001183 189.0
HFD3_k127_4680807_13 Methyltransferase FkbM domain - - - 0.00000000000000000000000000000000000000000004631 169.0
HFD3_k127_4680807_14 phosphinothricin N-acetyltransferase activity - - - 0.00000000000000000000000000000000000000001198 160.0
HFD3_k127_4680807_15 Cytochrome c554 and c-prime - - - 0.000000000000002448 85.0
HFD3_k127_4680807_16 PFAM Methyltransferase type 11 - - - 0.000000447 62.0
HFD3_k127_4680807_2 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 385.0
HFD3_k127_4680807_3 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 368.0
HFD3_k127_4680807_4 RmlD substrate binding domain K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 341.0
HFD3_k127_4680807_5 PFAM glycosyl transferase family 9 K02841 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001476 289.0
HFD3_k127_4680807_6 Glycosyl transferase family 2 K13005 - 2.4.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001685 299.0
HFD3_k127_4680807_7 Glycosyl transferase, family 2 - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002556 271.0
HFD3_k127_4680807_8 Glycosyl transferase family 2 K12984 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004653 251.0
HFD3_k127_4680807_9 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000385 256.0
HFD3_k127_4694209_0 response regulator receiver K10943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 458.0
HFD3_k127_4694209_1 PFAM ATP-binding region, ATPase domain protein K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000003217 201.0
HFD3_k127_4694209_2 - - - - 0.00000000003138 75.0
HFD3_k127_4696400_0 Belongs to the RtcB family K14415 - 6.5.1.3 1.236e-260 809.0
HFD3_k127_4696400_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 335.0
HFD3_k127_4696400_2 cobalamin synthesis protein, P47K - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 324.0
HFD3_k127_4696400_3 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000000000000000000000000000001862 167.0
HFD3_k127_4696400_4 - - - - 0.000001737 56.0
HFD3_k127_4705253_0 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 469.0
HFD3_k127_4705253_1 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000000000004068 121.0
HFD3_k127_4705253_2 redox-active disulfide protein 2 - - - 0.0000000000000000001977 93.0
HFD3_k127_4705253_3 SpoVT / AbrB like domain - - - 0.000000000002927 68.0
HFD3_k127_4713253_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.121e-198 630.0
HFD3_k127_4713253_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001885 280.0
HFD3_k127_4713253_2 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000000000000000000000000000000000000000000000000007318 188.0
HFD3_k127_4713610_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000008021 113.0
HFD3_k127_4713610_1 - - - - 0.000000000000004932 81.0
HFD3_k127_4713610_2 Putative zinc-finger - - - 0.00004554 52.0
HFD3_k127_4713610_3 - - - - 0.00006653 54.0
HFD3_k127_4721575_0 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 440.0
HFD3_k127_4721575_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006525 383.0
HFD3_k127_4721575_2 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 343.0
HFD3_k127_4721575_3 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 295.0
HFD3_k127_4721575_4 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000006624 234.0
HFD3_k127_4753771_0 Citrate lyase, alpha subunit (CitF) - - - 3.69e-276 865.0
HFD3_k127_4753771_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 4.219e-252 791.0
HFD3_k127_4753771_10 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 346.0
HFD3_k127_4753771_11 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627,K09699 - 2.3.1.12,2.3.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 349.0
HFD3_k127_4753771_12 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005027 321.0
HFD3_k127_4753771_13 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008163 303.0
HFD3_k127_4753771_14 Peptidase U62 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 308.0
HFD3_k127_4753771_15 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007503 298.0
HFD3_k127_4753771_16 RecF/RecN/SMC N terminal domain K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 302.0
HFD3_k127_4753771_17 Amino acid amide ABC transporter ATP-binding protein 1, HAAT family K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 287.0
HFD3_k127_4753771_18 PFAM ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 285.0
HFD3_k127_4753771_19 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.0000000000000000000000000000000000000000000000000000000003096 207.0
HFD3_k127_4753771_2 PFAM Aldehyde dehydrogenase - - - 1.56e-242 756.0
HFD3_k127_4753771_20 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000000000003528 192.0
HFD3_k127_4753771_21 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000004998 182.0
HFD3_k127_4753771_22 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000000000000000005235 173.0
HFD3_k127_4753771_23 Calcineurin-like phosphoesterase K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.0000000000000000000000000000000000000001664 163.0
HFD3_k127_4753771_24 Could be involved in septation K06412 - - 0.000000000000000000000000000001357 123.0
HFD3_k127_4753771_25 Divergent 4Fe-4S mono-cluster K05337 - - 0.000000000000000000004157 95.0
HFD3_k127_4753771_26 PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal K14534 - 4.2.1.120,5.3.3.3 0.0000000000003999 71.0
HFD3_k127_4753771_27 - - - - 0.0005539 53.0
HFD3_k127_4753771_3 Iron-containing alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 526.0
HFD3_k127_4753771_4 AAA ATPase, central domain protein K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000694 490.0
HFD3_k127_4753771_5 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003697 490.0
HFD3_k127_4753771_6 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002774 454.0
HFD3_k127_4753771_7 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 430.0
HFD3_k127_4753771_8 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 391.0
HFD3_k127_4753771_9 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 364.0
HFD3_k127_4754610_0 Domain of unknown function (DUF3536) - - - 3.483e-287 917.0
HFD3_k127_4754610_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700,K01236 - 2.4.1.18,3.2.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 520.0
HFD3_k127_4756865_0 COG0798 Arsenite efflux pump ACR3 and related K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 484.0
HFD3_k127_4756865_1 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 369.0
HFD3_k127_4756865_10 - - - - 0.0000000008437 69.0
HFD3_k127_4756865_2 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000002794 245.0
HFD3_k127_4756865_3 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000001132 243.0
HFD3_k127_4756865_4 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000513 189.0
HFD3_k127_4756865_5 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000001595 174.0
HFD3_k127_4756865_6 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000000000000000000000008821 157.0
HFD3_k127_4756865_7 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000000003426 118.0
HFD3_k127_4756865_9 PFAM histidine kinase, HAMP region domain protein - - - 0.00000000000000000000000000735 125.0
HFD3_k127_4759219_0 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 361.0
HFD3_k127_4759219_1 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000000000000000000000009751 171.0
HFD3_k127_4759219_2 helix_turn_helix, Lux Regulon - - - 0.000006607 51.0
HFD3_k127_4761935_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 1.771e-254 833.0
HFD3_k127_4761935_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 595.0
HFD3_k127_4761935_10 4Fe-4S single cluster domain K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000005658 240.0
HFD3_k127_4761935_11 PFAM Isochorismatase K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000000000000000000811 211.0
HFD3_k127_4761935_12 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000000000000001466 200.0
HFD3_k127_4761935_13 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000001192 107.0
HFD3_k127_4761935_14 Magnesium chelatase, subunit ChlI K03404,K03405 - 6.6.1.1 0.0000000000000000000001653 102.0
HFD3_k127_4761935_15 PFAM AsmA family protein K07289 - - 0.000000000000005305 89.0
HFD3_k127_4761935_16 Pfam:DUF1049 - - - 0.00000128 54.0
HFD3_k127_4761935_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 575.0
HFD3_k127_4761935_3 SMART ATPase, AAA type, core - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 500.0
HFD3_k127_4761935_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 432.0
HFD3_k127_4761935_5 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 409.0
HFD3_k127_4761935_6 THUMP K07444,K12297 - 2.1.1.173,2.1.1.264 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 398.0
HFD3_k127_4761935_7 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 399.0
HFD3_k127_4761935_8 Dimerisation domain of Zinc Transporter K13283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006629 269.0
HFD3_k127_4761935_9 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000008416 271.0
HFD3_k127_4787855_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1325.0
HFD3_k127_4787855_1 Glycosyl hydrolases family 15 - - - 2.337e-233 741.0
HFD3_k127_4787855_10 Amidinotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003398 290.0
HFD3_k127_4787855_11 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001255 265.0
HFD3_k127_4787855_12 Paraquat-inducible protein B - - - 0.0000000000000000000000000000000000000000000000000000000000000000001722 245.0
HFD3_k127_4787855_13 lysyl-tRNA synthetase K04568 - - 0.0000000000000000000000000000000000000000000000000000000000000000007115 240.0
HFD3_k127_4787855_14 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000001604 227.0
HFD3_k127_4787855_15 PBP superfamily domain K02040 - - 0.0000000000000000000000000000000000000000000000000000000002236 213.0
HFD3_k127_4787855_16 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000009014 194.0
HFD3_k127_4787855_17 Low affinity iron permease - - - 0.000000000000000000000000000000000000000000001158 169.0
HFD3_k127_4787855_18 paraquat-inducible protein A K03808 - - 0.00000000000000000000000000000000000000000001854 168.0
HFD3_k127_4787855_19 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000001939 176.0
HFD3_k127_4787855_2 Sugar (and other) transporter K03446 - - 3.283e-200 637.0
HFD3_k127_4787855_20 Class I peptide chain release factor K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.00000000000000000000000000000000000000004715 158.0
HFD3_k127_4787855_21 GYD domain - - - 0.0000000000000000000000000000000000002067 144.0
HFD3_k127_4787855_22 PFAM YbaK prolyl-tRNA synthetase associated region K19055 - - 0.00000000000000000000000000000001502 137.0
HFD3_k127_4787855_23 TIGRFAM cytochrome C family protein - - - 0.000000000000000000000000000004142 132.0
HFD3_k127_4787855_24 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000000004068 120.0
HFD3_k127_4787855_25 Biotin-lipoyl like K07799 - - 0.00000000000000000000001217 101.0
HFD3_k127_4787855_26 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000001655 120.0
HFD3_k127_4787855_27 Protein of unknown function (DUF2628) - - - 0.00000000000000001243 90.0
HFD3_k127_4787855_28 enoyl-CoA hydratase K15866 - 5.3.3.18 0.000000000000001209 94.0
HFD3_k127_4787855_29 - - - - 0.00000000000007745 74.0
HFD3_k127_4787855_3 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 579.0
HFD3_k127_4787855_30 Thioesterase superfamily K02614 - - 0.00000000003892 69.0
HFD3_k127_4787855_31 - - - - 0.0000001401 57.0
HFD3_k127_4787855_32 Class III cytochrome C family - - - 0.0000005674 56.0
HFD3_k127_4787855_33 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.000002466 57.0
HFD3_k127_4787855_34 Putative zinc-finger - - - 0.0001853 53.0
HFD3_k127_4787855_35 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.0003133 43.0
HFD3_k127_4787855_4 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 522.0
HFD3_k127_4787855_5 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 435.0
HFD3_k127_4787855_6 PFAM LOR SDH bifunctional - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 412.0
HFD3_k127_4787855_7 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007922 391.0
HFD3_k127_4787855_8 HlyD membrane-fusion protein of T1SS K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 304.0
HFD3_k127_4787855_9 Major Facilitator Superfamily K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003151 295.0
HFD3_k127_48124_0 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 377.0
HFD3_k127_48124_1 Mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000009627 273.0
HFD3_k127_48124_2 Seryl-tRNA synthetase N-terminal domain K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000009425 250.0
HFD3_k127_48124_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000004996 139.0
HFD3_k127_48124_4 Rubrerythrin - - - 0.00000000000000004722 93.0
HFD3_k127_48124_5 Metallo-beta-lactamase superfamily K22405 - 1.6.3.4 0.0000000000005527 68.0
HFD3_k127_48124_6 Rubrerythrin - - - 0.0000000000009099 74.0
HFD3_k127_4824115_0 CHASE2 K01768 - 4.6.1.1 5.616e-201 645.0
HFD3_k127_4824115_1 FecR protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 396.0
HFD3_k127_4859291_0 Alpha amylase, catalytic domain K06044 - 5.4.99.15 5.566e-313 985.0
HFD3_k127_4859291_1 Belongs to the glycosyl hydrolase 57 family - - - 0.00000000000000000000000000000000000003271 148.0
HFD3_k127_4872957_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1350.0
HFD3_k127_4872957_1 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 501.0
HFD3_k127_4872957_10 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005488,GO:0005507,GO:0005575,GO:0005576,GO:0005615,GO:0005623,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0030288,GO:0030313,GO:0031975,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044421,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 0.00000000000000000000000000000000000000000000005693 191.0
HFD3_k127_4872957_11 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000008237 175.0
HFD3_k127_4872957_12 Haem-degrading - - - 0.0000000000000000000000000000000000001745 150.0
HFD3_k127_4872957_13 - - - - 0.00000000000000000000000007431 108.0
HFD3_k127_4872957_14 - - - - 0.000000000000000001844 88.0
HFD3_k127_4872957_15 Tripartite tricarboxylate transporter TctB family K07794 - - 0.000000005978 63.0
HFD3_k127_4872957_16 Belongs to the 'phage' integrase family - - - 0.000008183 49.0
HFD3_k127_4872957_17 Cupin 2, conserved barrel domain protein - - - 0.0003573 48.0
HFD3_k127_4872957_2 PFAM Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007297 382.0
HFD3_k127_4872957_3 Psort location CytoplasmicMembrane, score K07793 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004001 359.0
HFD3_k127_4872957_4 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 353.0
HFD3_k127_4872957_5 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008374 350.0
HFD3_k127_4872957_6 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 330.0
HFD3_k127_4872957_7 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 288.0
HFD3_k127_4872957_8 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007401 246.0
HFD3_k127_4872957_9 Membrane - - - 0.000000000000000000000000000000000000000000000000000000461 205.0
HFD3_k127_4876000_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 352.0
HFD3_k127_4876000_1 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 297.0
HFD3_k127_4876000_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009168 276.0
HFD3_k127_4876000_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000007762 237.0
HFD3_k127_4876000_4 PFAM AMMECR1 domain protein K09141 - - 0.0000000000000000000000000000000000000000000000945 184.0
HFD3_k127_4876000_5 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000001206 115.0
HFD3_k127_4876000_6 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.0000000000000000000001394 99.0
HFD3_k127_4895883_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1137.0
HFD3_k127_4895883_1 PFAM Glycosyl transferases group 1 K13057 - 2.4.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 537.0
HFD3_k127_4895883_10 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700,K01236 - 2.4.1.18,3.2.1.141 0.0000000000000000000000000000000001659 145.0
HFD3_k127_4895883_11 Necessary for formate dehydrogenase activity K02380 - - 0.000000000000000000000000000001161 137.0
HFD3_k127_4895883_12 His Kinase A (phosphoacceptor) domain - - - 0.000000000000008146 81.0
HFD3_k127_4895883_13 Parallel beta-helix repeats - - - 0.000000000007848 70.0
HFD3_k127_4895883_2 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008629 523.0
HFD3_k127_4895883_3 Mechanosensitive ion channel K03442 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 383.0
HFD3_k127_4895883_4 4Fe-4S ferredoxin K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 293.0
HFD3_k127_4895883_5 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001326 281.0
HFD3_k127_4895883_6 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000002048 219.0
HFD3_k127_4895883_7 Polysulfide reductase - - - 0.0000000000000000000000000000000000000000000000000002657 212.0
HFD3_k127_4895883_8 PFAM Bacterial regulatory protein, Fis family K17763 - - 0.0000000000000000000000000000000000000000003485 182.0
HFD3_k127_4895883_9 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000265 164.0
HFD3_k127_5005455_0 GTP cyclohydrolase I K00950,K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009108,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0042455,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901657,GO:1901659 2.7.6.3,3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000005984 249.0
HFD3_k127_5005455_1 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000000000000000000000009334 176.0
HFD3_k127_5005455_2 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000003766 115.0
HFD3_k127_5005455_3 domain protein K20276 - - 0.0000000000000000002402 95.0
HFD3_k127_5005455_4 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000001698 87.0
HFD3_k127_5005455_5 Rubrerythrin - - - 0.0000000000005499 76.0
HFD3_k127_5005455_6 Protein of unknown function (DUF3106) - - - 0.00009044 53.0
HFD3_k127_5005455_7 Putative zinc-finger - - - 0.0004157 50.0
HFD3_k127_5006876_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 549.0
HFD3_k127_5006876_1 Iron-only hydrogenase maturation rSAM protein HydG K03150 - 4.1.99.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 415.0
HFD3_k127_5006876_10 Colicin V production protein K03558 - - 0.000000000313 68.0
HFD3_k127_5006876_2 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 397.0
HFD3_k127_5006876_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 308.0
HFD3_k127_5006876_4 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005836 304.0
HFD3_k127_5006876_5 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000476 279.0
HFD3_k127_5006876_6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000004984 214.0
HFD3_k127_5006876_7 - - - - 0.0000000000000000000000000000000000000000000002115 185.0
HFD3_k127_5006876_8 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.0000000000000000000000000000000000000000003704 166.0
HFD3_k127_5006876_9 COG2104 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.000000000032 74.0
HFD3_k127_501803_0 B12 binding domain K00548 - 2.1.1.13 0.0 1045.0
HFD3_k127_501803_1 homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 4.384e-283 882.0
HFD3_k127_501803_10 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.000000000000000000000000000000000000001053 155.0
HFD3_k127_501803_11 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000003926 133.0
HFD3_k127_501803_12 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000001098 127.0
HFD3_k127_501803_13 Belongs to the Fur family K09825 - - 0.00000000000000000000006918 102.0
HFD3_k127_501803_14 Cytochrome b(C-terminal)/b6/petD K00412 - - 0.000000000000000000006441 97.0
HFD3_k127_501803_15 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.00000000000003135 86.0
HFD3_k127_501803_16 Rieske [2Fe-2S] domain - - - 0.000000000005985 75.0
HFD3_k127_501803_17 TonB C terminal - - - 0.0002215 52.0
HFD3_k127_501803_2 Belongs to the citrate synthase family K01647,K01659 - 2.3.3.1,2.3.3.5 5.097e-221 696.0
HFD3_k127_501803_3 denitrification pathway K02569,K15876 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008175 421.0
HFD3_k127_501803_4 SMART Nucleotide binding protein, PINc K07175 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 373.0
HFD3_k127_501803_5 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000000000000000000000983 271.0
HFD3_k127_501803_6 Cytochrome c554 and c-prime K03620 - - 0.000000000000000000000000000000000000000000000000000000000000000000000045 270.0
HFD3_k127_501803_7 Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions K02635 GO:0005575,GO:0005622,GO:0005623,GO:0009512,GO:0009579,GO:0016020,GO:0032991,GO:0034357,GO:0042651,GO:0044424,GO:0044436,GO:0044464,GO:0070069 - 0.000000000000000000000000000000000000000000000000000000000002399 217.0
HFD3_k127_501803_8 MotA/TolQ/ExbB proton channel family K03562 - - 0.00000000000000000000000000000000000000000000000000000002819 205.0
HFD3_k127_501803_9 PFAM OmpA MotB domain protein K03640 - - 0.0000000000000000000000000000000000000001517 158.0
HFD3_k127_5139615_0 aconitate hydratase K01681 - 4.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 494.0
HFD3_k127_5139615_1 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 388.0
HFD3_k127_5139615_2 regulatory protein LysR K02019 - - 0.00000000000000000000000000000000000000000000000001448 186.0
HFD3_k127_5139615_3 molybdopterin-guanine dinucleotide biosynthesis K03753 - - 0.000000000000000000000000000143 124.0
HFD3_k127_5199696_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1339.0
HFD3_k127_5199696_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K07516 - 1.1.1.35 2.846e-278 877.0
HFD3_k127_5199696_2 Thiolase, C-terminal domain K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009883 506.0
HFD3_k127_5199696_3 Single cache domain 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 358.0
HFD3_k127_5199696_4 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009343 303.0
HFD3_k127_5199696_5 catechol 2,3-dioxygenase activity - - - 0.00000000000000000000000000002368 123.0
HFD3_k127_5199696_6 Cytochrome c K08906,K12263 - - 0.000000000000008867 78.0
HFD3_k127_5199696_7 - - - - 0.000000000004912 76.0
HFD3_k127_5199696_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000002438 49.0
HFD3_k127_5235613_0 polyribonucleotide nucleotidyltransferase activity K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 2.015e-238 765.0
HFD3_k127_5235613_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 1.038e-209 665.0
HFD3_k127_5235613_10 Domain of unknown function (DUF4124) K08309 - - 0.0000000000000000000000000000000000000000000000003533 181.0
HFD3_k127_5235613_11 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000008136 158.0
HFD3_k127_5235613_12 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000009968 129.0
HFD3_k127_5235613_13 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000002946 106.0
HFD3_k127_5235613_14 - - - - 0.0000000000000001124 88.0
HFD3_k127_5235613_15 COG2801 Transposase and inactivated derivatives K07497 - - 0.000000000001344 69.0
HFD3_k127_5235613_2 Glutamine amidotransferases class-II K00764 - 2.4.2.14 7.914e-197 625.0
HFD3_k127_5235613_3 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 597.0
HFD3_k127_5235613_4 Glycosyltransferase Family 4 K08256 - 2.4.1.345 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 478.0
HFD3_k127_5235613_5 PFAM peptidase M16 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 357.0
HFD3_k127_5235613_6 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 304.0
HFD3_k127_5235613_7 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000001137 215.0
HFD3_k127_5235613_8 dUTPase K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.000000000000000000000000000000000000000000000000001439 188.0
HFD3_k127_5235613_9 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000002232 203.0
HFD3_k127_5246808_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 5.281e-201 647.0
HFD3_k127_5246808_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 1.58e-199 647.0
HFD3_k127_5246808_10 esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000098 340.0
HFD3_k127_5246808_11 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 307.0
HFD3_k127_5246808_12 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008056 300.0
HFD3_k127_5246808_13 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006394 297.0
HFD3_k127_5246808_14 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001873 276.0
HFD3_k127_5246808_15 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000006735 273.0
HFD3_k127_5246808_16 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002164 250.0
HFD3_k127_5246808_17 oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000449 241.0
HFD3_k127_5246808_18 Belongs to the universal ribosomal protein uS5 family K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000001487 219.0
HFD3_k127_5246808_19 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000003212 221.0
HFD3_k127_5246808_2 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 602.0
HFD3_k127_5246808_20 Indole-3-glycerol phosphate synthase K01609 GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000003781 224.0
HFD3_k127_5246808_21 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000197 211.0
HFD3_k127_5246808_22 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000003257 210.0
HFD3_k127_5246808_23 PFAM iron dependent repressor K03709 - - 0.00000000000000000000000000000000000000000000000000000002056 206.0
HFD3_k127_5246808_24 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000002816 205.0
HFD3_k127_5246808_25 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000007252 192.0
HFD3_k127_5246808_26 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000004641 189.0
HFD3_k127_5246808_27 Binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000009373 185.0
HFD3_k127_5246808_28 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000008529 171.0
HFD3_k127_5246808_29 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000001028 170.0
HFD3_k127_5246808_3 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 556.0
HFD3_k127_5246808_30 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000002601 159.0
HFD3_k127_5246808_31 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000009418 153.0
HFD3_k127_5246808_32 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000037 147.0
HFD3_k127_5246808_33 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000002153 144.0
HFD3_k127_5246808_34 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.000000000000000000000000000000000008385 136.0
HFD3_k127_5246808_35 Diguanylate cyclase - - - 0.000000000000000000000000000000000009713 156.0
HFD3_k127_5246808_36 Ribosomal proteins 50S L24/mitochondrial 39S L24 K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000003184 135.0
HFD3_k127_5246808_37 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000006634 124.0
HFD3_k127_5246808_38 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000001372 117.0
HFD3_k127_5246808_39 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000002162 111.0
HFD3_k127_5246808_4 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 546.0
HFD3_k127_5246808_40 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000003187 118.0
HFD3_k127_5246808_41 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000002389 105.0
HFD3_k127_5246808_42 'Cold-shock' DNA-binding domain K03704 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000716 96.0
HFD3_k127_5246808_43 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000002472 75.0
HFD3_k127_5246808_44 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000001667 73.0
HFD3_k127_5246808_45 Ribosomal protein L30p/L7e K02907 - - 0.00000000006393 71.0
HFD3_k127_5246808_46 PEGA domain - - - 0.00000001936 66.0
HFD3_k127_5246808_47 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.000002216 54.0
HFD3_k127_5246808_48 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00002869 48.0
HFD3_k127_5246808_49 - - - - 0.000946 44.0
HFD3_k127_5246808_5 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000414 503.0
HFD3_k127_5246808_6 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 498.0
HFD3_k127_5246808_7 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 460.0
HFD3_k127_5246808_8 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 437.0
HFD3_k127_5246808_9 Ribosomal Proteins L2, C-terminal domain K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005212 403.0
HFD3_k127_5297312_0 PFAM Type II secretion system protein E K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 553.0
HFD3_k127_5297312_1 General secretion pathway protein F K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002844 291.0
HFD3_k127_5297312_2 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000000001851 236.0
HFD3_k127_5297312_3 general secretion pathway protein G K02456 - - 0.00000000000000000000000000000000000000000000000004105 198.0
HFD3_k127_5297312_4 PFAM General secretion pathway protein K K02460 - - 0.00000000000000000000000000000000005677 153.0
HFD3_k127_5297312_5 General secretion pathway protein K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.000000000000008271 87.0
HFD3_k127_5297312_6 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02461 - - 0.0000008316 61.0
HFD3_k127_5297312_7 general secretion pathway protein K02456,K02457,K02458,K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.000002364 55.0
HFD3_k127_5297312_9 Prokaryotic N-terminal methylation motif K02457 - - 0.00003212 55.0
HFD3_k127_5382991_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1307.0
HFD3_k127_5382991_1 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 552.0
HFD3_k127_5382991_10 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000001146 91.0
HFD3_k127_5382991_11 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.00000000000000173 87.0
HFD3_k127_5382991_12 peptidyl-prolyl cis-trans isomerase K03771 - 5.2.1.8 0.0000000000000812 83.0
HFD3_k127_5382991_13 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.00000003653 58.0
HFD3_k127_5382991_2 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006139 499.0
HFD3_k127_5382991_3 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 349.0
HFD3_k127_5382991_4 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007054 312.0
HFD3_k127_5382991_5 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000001128 198.0
HFD3_k127_5382991_6 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000001503 188.0
HFD3_k127_5382991_7 Tautomerase enzyme K01821 - 5.3.2.6 0.0000000000000000000000000001146 118.0
HFD3_k127_5382991_8 metal cluster binding - - - 0.00000000000000000000000001974 117.0
HFD3_k127_5382991_9 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000006974 96.0
HFD3_k127_5437086_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1030.0
HFD3_k127_5437086_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 1.186e-207 675.0
HFD3_k127_5437086_10 nitrogen compound transport K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 342.0
HFD3_k127_5437086_11 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 336.0
HFD3_k127_5437086_12 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008658 330.0
HFD3_k127_5437086_13 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 331.0
HFD3_k127_5437086_14 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000003484 255.0
HFD3_k127_5437086_15 - - - - 0.000000000000000000000000000000000000000000000000000000000000000002369 239.0
HFD3_k127_5437086_16 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000001356 230.0
HFD3_k127_5437086_17 PFAM Appr-1-p processing - - - 0.000000000000000000000000000000000000000000000000000001479 218.0
HFD3_k127_5437086_18 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000003583 173.0
HFD3_k127_5437086_19 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000001818 182.0
HFD3_k127_5437086_2 pfam fad - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 544.0
HFD3_k127_5437086_20 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000000006121 164.0
HFD3_k127_5437086_21 adenylylsulfate kinase activity K00860,K00955 - 2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000004854 157.0
HFD3_k127_5437086_22 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.000000000000000000000000000000000000001377 150.0
HFD3_k127_5437086_23 FecR protein - - - 0.00000000000000000000000000000000000003352 163.0
HFD3_k127_5437086_24 Domain of unknown function (DUF1992) - - - 0.00000000000000000000000000000000000007841 151.0
HFD3_k127_5437086_25 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000005152 123.0
HFD3_k127_5437086_26 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.000000000000000000000000002313 128.0
HFD3_k127_5437086_27 Transcriptional regulator - - - 0.0000000000000000006318 90.0
HFD3_k127_5437086_28 - - - - 0.00000000000006224 78.0
HFD3_k127_5437086_29 - - - - 0.0000000000004659 78.0
HFD3_k127_5437086_3 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 516.0
HFD3_k127_5437086_4 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 499.0
HFD3_k127_5437086_5 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 439.0
HFD3_k127_5437086_6 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009958 436.0
HFD3_k127_5437086_7 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005858 422.0
HFD3_k127_5437086_8 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007375 392.0
HFD3_k127_5437086_9 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005105 376.0
HFD3_k127_5451949_0 PFAM Sodium sulphate symporter K03319,K11106 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 593.0
HFD3_k127_5451949_1 PFAM Acetyl-CoA hydrolase transferase K01067 - 3.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007349 475.0
HFD3_k127_5451949_2 membrane protein, TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 454.0
HFD3_k127_5451949_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005234 309.0
HFD3_k127_5451949_4 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000001461 161.0
HFD3_k127_5451949_5 - - - - 0.000000000000000000000000000000000000000005639 167.0
HFD3_k127_5451949_6 DoxX family K15977 - - 0.00000000000000000000005277 104.0
HFD3_k127_5451949_7 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000001134 95.0
HFD3_k127_5451949_8 Belongs to the WrbA family K03809 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.6.5.2 0.0000000000008017 68.0
HFD3_k127_5451949_9 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.000005126 52.0
HFD3_k127_5476583_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 7.153e-212 672.0
HFD3_k127_5476583_1 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 7.476e-209 681.0
HFD3_k127_5476583_10 Protein of unknown function, DUF393 - - - 0.00000000000000000000000001421 116.0
HFD3_k127_5476583_11 hydrogen uptake protein K03605 - - 0.000000000000000000000002702 117.0
HFD3_k127_5476583_12 - - - - 0.000000000000000000000003377 107.0
HFD3_k127_5476583_13 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000025 116.0
HFD3_k127_5476583_14 HupF/HypC family K04653 - - 0.00000000000000004439 86.0
HFD3_k127_5476583_15 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.000000000004869 70.0
HFD3_k127_5476583_16 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.00000000008228 76.0
HFD3_k127_5476583_17 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000005968 55.0
HFD3_k127_5476583_18 binding domain protein - - - 0.0004928 51.0
HFD3_k127_5476583_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 588.0
HFD3_k127_5476583_3 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005848 446.0
HFD3_k127_5476583_4 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 406.0
HFD3_k127_5476583_5 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 353.0
HFD3_k127_5476583_6 PFAM V-type ATPase 116 kDa K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005686 345.0
HFD3_k127_5476583_7 2-methylcitrate dehydratase K01720 - 4.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000009155 252.0
HFD3_k127_5476583_8 PFAM regulatory protein TetR K16137 - - 0.0000000000000000000000000000000000000000000000000000000000004457 218.0
HFD3_k127_5476583_9 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.0000000000000000000000000000000000000000000001204 182.0
HFD3_k127_5481860_0 response regulator K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004613 479.0
HFD3_k127_5481860_1 PAS domain K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 478.0
HFD3_k127_5481860_10 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000000000000000000003484 158.0
HFD3_k127_5481860_11 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000001925 128.0
HFD3_k127_5481860_12 COG NOG14600 non supervised orthologous group - - - 0.00000000000000000000000000005458 115.0
HFD3_k127_5481860_13 Type II secretion system protein F domain-containing protein 1 K12510 - - 0.00000000000000000000008193 114.0
HFD3_k127_5481860_14 Protein of unknown function (DUF2905) - - - 0.000000000000000000003174 94.0
HFD3_k127_5481860_15 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.0000000000002584 82.0
HFD3_k127_5481860_16 Domain of unknown function (DUF4390) - - - 0.000000000001254 76.0
HFD3_k127_5481860_19 Type II secretion system (T2SS), protein F K12510 - - 0.00000007318 63.0
HFD3_k127_5481860_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005293 455.0
HFD3_k127_5481860_20 COG NOG14600 non supervised orthologous group - - - 0.0000003037 53.0
HFD3_k127_5481860_3 Type II IV secretion system protein K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 426.0
HFD3_k127_5481860_4 regulation of RNA biosynthetic process - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 317.0
HFD3_k127_5481860_5 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002654 293.0
HFD3_k127_5481860_6 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000004332 241.0
HFD3_k127_5481860_7 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000004571 210.0
HFD3_k127_5481860_8 Belongs to the GSP D family K02280 - - 0.00000000000000000000000000000000000000000000000000009362 205.0
HFD3_k127_5483994_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000414 284.0
HFD3_k127_5483994_1 Carotenoid biosynthesis protein K22502 - 5.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000002446 267.0
HFD3_k127_5483994_2 Cupin domain - - - 0.0000000000000000000000007098 110.0
HFD3_k127_5483994_3 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000002722 104.0
HFD3_k127_5487678_0 FAD-dependent dehydrogenases - - - 1.289e-197 625.0
HFD3_k127_5487678_1 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005961 470.0
HFD3_k127_5487678_10 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000005488 159.0
HFD3_k127_5487678_11 CoA binding domain K06929 - - 0.0000000000000000000000000000000000000007817 158.0
HFD3_k127_5487678_12 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000009232 136.0
HFD3_k127_5487678_13 diguanylate cyclase activity K02000,K04767,K05847,K07168,K09137 - 3.6.3.32 0.000000000000000000000000000001463 129.0
HFD3_k127_5487678_2 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 437.0
HFD3_k127_5487678_3 PFAM Alcohol dehydrogenase K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 436.0
HFD3_k127_5487678_4 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 337.0
HFD3_k127_5487678_5 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006748 334.0
HFD3_k127_5487678_6 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 321.0
HFD3_k127_5487678_7 Belongs to the UPF0173 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002168 243.0
HFD3_k127_5487678_8 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000002256 217.0
HFD3_k127_5487678_9 GHMP kinases N terminal domain K07031 - 2.7.1.168 0.00000000000000000000000000000000000000001028 168.0
HFD3_k127_5499924_0 'glutamate synthase K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 1.319e-217 684.0
HFD3_k127_5499924_1 Major Facilitator Superfamily K08224 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 419.0
HFD3_k127_5499924_2 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000006332 233.0
HFD3_k127_5499924_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000009557 234.0
HFD3_k127_5499924_4 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 GO:0001130,GO:0003674,GO:0003700,GO:0003824,GO:0003908,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006355,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016740,GO:0016741,GO:0018125,GO:0018193,GO:0018198,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044728,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0046872,GO:0046914,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070988,GO:0071704,GO:0080090,GO:0080111,GO:0090304,GO:0140110,GO:1901360,GO:1901564,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 2.1.1.63 0.00000000000000000000000000000000000000000000000000000001412 203.0
HFD3_k127_5499924_5 - - - - 0.0000000000000000000000000000000000000000000007705 181.0
HFD3_k127_5499924_6 - - - - 0.0000000000000000000000000000000000003371 145.0
HFD3_k127_5499924_7 Dodecin K09165 - - 0.00000000000000000000003646 106.0
HFD3_k127_5499924_8 carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.00000000000000000007383 90.0
HFD3_k127_5499924_9 Smr protein MutS2 - - - 0.00000000000001701 77.0
HFD3_k127_550284_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1079.0
HFD3_k127_550284_1 2Fe-2S iron-sulfur cluster binding domain K00240,K00245 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009813 434.0
HFD3_k127_5510204_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 4.915e-204 665.0
HFD3_k127_5510204_1 PFAM peptidase U32 K08303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 376.0
HFD3_k127_5510204_10 Domain of unknown function (DUF1858) - - - 0.000002458 54.0
HFD3_k127_5510204_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 363.0
HFD3_k127_5510204_3 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 303.0
HFD3_k127_5510204_4 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000004974 212.0
HFD3_k127_5510204_5 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000002183 204.0
HFD3_k127_5510204_6 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000002569 216.0
HFD3_k127_5510204_7 phosphinothricin N-acetyltransferase activity - - - 0.0000000000000000000000000000000000000000002815 168.0
HFD3_k127_5510204_8 domain, Protein - - - 0.00000000000000000000000005882 114.0
HFD3_k127_5510204_9 Domain of unknown function (DUF4442) - - - 0.0000000007263 66.0
HFD3_k127_5524850_0 beta-glucosidase activity K05350 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003131 351.0
HFD3_k127_5524850_1 Two component transcriptional regulator, winged helix family K07658 - - 0.00000000000000000000000000000000000000000004662 166.0
HFD3_k127_5524850_2 Diacylglycerol kinase - - - 0.0000000000000000000000000000000000001366 151.0
HFD3_k127_5547966_0 MlaD protein K06192 - - 0.0000000000000000000000000000000000000000000000000000000000000005618 231.0
HFD3_k127_5547966_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000000000000000001133 197.0
HFD3_k127_5547966_2 - - - - 0.0000000000000000000000000000000000004321 144.0
HFD3_k127_5547966_3 ABC-type transport auxiliary lipoprotein component K09857 - - 0.000000000000000000000000000002994 132.0
HFD3_k127_5558122_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 426.0
HFD3_k127_5558122_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 366.0
HFD3_k127_5558122_2 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006449 323.0
HFD3_k127_5558122_3 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 304.0
HFD3_k127_5558122_4 PFAM ABC transporter related K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 305.0
HFD3_k127_5558122_5 dienelactone hydrolase - - - 0.000000000000000000000000000000000000000000002103 166.0
HFD3_k127_5558122_6 AMP-binding enzyme C-terminal domain K00666 - - 0.00000000000000000000000000000000000000000003132 164.0
HFD3_k127_5564318_0 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 477.0
HFD3_k127_5564318_1 PFAM phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 449.0
HFD3_k127_5564318_10 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000009262 107.0
HFD3_k127_5564318_11 Rubrerythrin - - - 0.000000008188 64.0
HFD3_k127_5564318_12 Glutaredoxin K03676 - - 0.00000009362 55.0
HFD3_k127_5564318_13 Sigma-54 interaction domain - - - 0.0005701 51.0
HFD3_k127_5564318_2 2-nitropropane dioxygenase K02371 - 1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 413.0
HFD3_k127_5564318_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007949 376.0
HFD3_k127_5564318_4 Ferredoxin--NADP reductase K21567 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 308.0
HFD3_k127_5564318_5 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002286 246.0
HFD3_k127_5564318_6 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000003767 250.0
HFD3_k127_5564318_7 Glyoxalase-like domain K05606 - 5.1.99.1 0.00000000000000000000000000000000000000000007004 177.0
HFD3_k127_5564318_8 Diacylglycerol kinase catalytic domain (presumed) - - - 0.00000000000000000000000000000000000000000009791 172.0
HFD3_k127_5564318_9 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000001012 156.0
HFD3_k127_5639431_0 Pyruvate synthase K00169 - 1.2.7.1 7.909e-294 936.0
HFD3_k127_5639431_1 helix_turn_helix, Lux Regulon - - - 4.448e-220 694.0
HFD3_k127_5639431_10 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 326.0
HFD3_k127_5639431_11 peptidase U32 K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005626 303.0
HFD3_k127_5639431_12 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 315.0
HFD3_k127_5639431_13 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000007348 231.0
HFD3_k127_5639431_14 AAA domain, putative AbiEii toxin, Type IV TA system K01996 - - 0.0000000000000000000000000000000000000000000000000005105 194.0
HFD3_k127_5639431_15 PFAM Roadblock LC7 family protein - - - 0.000000000000000000000000000000000000000000000001815 179.0
HFD3_k127_5639431_16 Belongs to the binding-protein-dependent transport system permease family K11960 - - 0.000000000000000000000000000000000000000000000003003 196.0
HFD3_k127_5639431_17 trehalose biosynthetic process K01087 - 3.1.3.12 0.0000000000000000000000000000000000000000000005886 178.0
HFD3_k127_5639431_18 ABC transporter K01995 - - 0.00000000000000000000000000000000000000005645 173.0
HFD3_k127_5639431_19 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000001189 155.0
HFD3_k127_5639431_2 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 392.0
HFD3_k127_5639431_20 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000003322 136.0
HFD3_k127_5639431_21 CBS domain K04767 - - 0.000000000000000000000000000000001252 137.0
HFD3_k127_5639431_22 - - - - 0.000003731 56.0
HFD3_k127_5639431_3 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 399.0
HFD3_k127_5639431_4 Voltage gated chloride channel K03281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 376.0
HFD3_k127_5639431_5 oxidoreductase gamma subunit K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 360.0
HFD3_k127_5639431_6 PFAM peptidase U32 K08303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000376 349.0
HFD3_k127_5639431_7 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004234 351.0
HFD3_k127_5639431_8 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 357.0
HFD3_k127_5639431_9 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 323.0
HFD3_k127_5667208_0 COG0457 FOG TPR repeat - - - 3.494e-261 817.0
HFD3_k127_5667208_1 FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 511.0
HFD3_k127_5667208_10 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000001164 188.0
HFD3_k127_5667208_11 Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein) - - - 0.00000000000000000000000000000000000004678 152.0
HFD3_k127_5667208_13 - - - - 0.0000000000007461 79.0
HFD3_k127_5667208_14 Serine aminopeptidase, S33 - - - 0.00000001557 57.0
HFD3_k127_5667208_15 Domain of unknown function (DUF1330) - - - 0.0000002704 56.0
HFD3_k127_5667208_16 Domain of unknown function (DUF4398) - - - 0.00000331 54.0
HFD3_k127_5667208_17 Cupin domain - - - 0.00001864 51.0
HFD3_k127_5667208_19 - - - - 0.0009684 46.0
HFD3_k127_5667208_2 Pirin K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007604 440.0
HFD3_k127_5667208_3 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005402 389.0
HFD3_k127_5667208_4 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 312.0
HFD3_k127_5667208_5 Protein of unknown function (DUF3455) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001329 258.0
HFD3_k127_5667208_6 Carotenoid biosynthesis protein K22502 - 5.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000005062 255.0
HFD3_k127_5667208_7 pfkB family carbohydrate kinase K18478 - 2.7.1.184 0.000000000000000000000000000000000000000000000000000000000005818 220.0
HFD3_k127_5667208_8 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000007443 190.0
HFD3_k127_5667208_9 PFAM oxidoreductase, molybdopterin binding - - - 0.00000000000000000000000000000000000000000000000005479 190.0
HFD3_k127_5704135_0 AMP-binding enzyme C-terminal domain K08295 - 6.2.1.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 297.0
HFD3_k127_570549_0 tRNA nucleotidyltransferase poly(A) polymerase K00974 - 2.7.7.72 2.195e-265 843.0
HFD3_k127_570549_1 Fumarate reductase, iron-sulfur protein K00240,K00245 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005478 439.0
HFD3_k127_570549_2 fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 426.0
HFD3_k127_570549_3 TIGRFAM tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 413.0
HFD3_k127_570549_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000008491 224.0
HFD3_k127_570549_5 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000001542 220.0
HFD3_k127_570549_6 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.000000000000000000000000000000000000000000000000000000001425 213.0
HFD3_k127_570549_7 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000327 182.0
HFD3_k127_5720726_0 DNA polymerase K02347 - - 9.963e-208 661.0
HFD3_k127_5720726_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 609.0
HFD3_k127_5720726_10 Mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000627 302.0
HFD3_k127_5720726_11 Inositol monophosphatase K01082,K01092 GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006369 295.0
HFD3_k127_5720726_12 pfam abc K02006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000287 275.0
HFD3_k127_5720726_13 cobalt ion transport K02007 GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015675,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000002718 244.0
HFD3_k127_5720726_14 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - 0.0000000000000000000000000000000000000001209 158.0
HFD3_k127_5720726_15 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000006911 153.0
HFD3_k127_5720726_16 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.000000000000000000000000000000000001972 141.0
HFD3_k127_5720726_17 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000007941 139.0
HFD3_k127_5720726_18 Cobalt transport protein K02008 - - 0.000000000000000000000000000000346 138.0
HFD3_k127_5720726_19 PFAM Cupin 2 conserved barrel domain protein - - - 0.00000000000000000000002603 110.0
HFD3_k127_5720726_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 521.0
HFD3_k127_5720726_20 - - - - 0.0000000000000000003705 88.0
HFD3_k127_5720726_21 Rubrerythrin - - - 0.0000000000000000005672 93.0
HFD3_k127_5720726_22 Rubrerythrin - - - 0.000000000000002753 82.0
HFD3_k127_5720726_23 cobalt ion transport K02009 - - 0.000000000000004726 87.0
HFD3_k127_5720726_24 Periplasmic protein TonB links inner and outer membranes K03832 - - 0.000000000003701 69.0
HFD3_k127_5720726_25 PFAM YcfA family protein - - - 0.0000000003584 64.0
HFD3_k127_5720726_26 PFAM Flavin reductase like domain - - - 0.0000001342 63.0
HFD3_k127_5720726_27 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.0000005263 51.0
HFD3_k127_5720726_28 uncharacterised conserved protein UCP017998 - - - 0.000002085 59.0
HFD3_k127_5720726_3 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007213 532.0
HFD3_k127_5720726_4 Mycolic acid cyclopropane synthetase K00574,K20238 - 2.1.1.317,2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007843 530.0
HFD3_k127_5720726_5 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 481.0
HFD3_k127_5720726_6 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007834 429.0
HFD3_k127_5720726_7 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11779,K11784 - 1.21.98.1,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 426.0
HFD3_k127_5720726_8 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000498 364.0
HFD3_k127_5720726_9 His Kinase A (phosphoacceptor) domain K10125 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 345.0
HFD3_k127_5724253_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0 1444.0
HFD3_k127_5724253_1 4Fe-4S dicluster domain K00124 GO:0005575,GO:0005623,GO:0009326,GO:0032991,GO:0042597,GO:0044464,GO:1902494 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 393.0
HFD3_k127_5724253_2 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006999 318.0
HFD3_k127_5724253_3 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000001993 165.0
HFD3_k127_5724253_4 PFAM DSBA oxidoreductase - - - 0.0005555 44.0
HFD3_k127_5735826_0 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007731 268.0
HFD3_k127_5735826_1 Domain of unknown function (DUF4388) - - - 0.0002429 45.0
HFD3_k127_5735826_2 Tetratricopeptide TPR_2 repeat protein - - - 0.0007765 52.0
HFD3_k127_5746598_0 Arginosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 606.0
HFD3_k127_5746598_1 PFAM fumarate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 550.0
HFD3_k127_5746598_2 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 458.0
HFD3_k127_5746598_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 359.0
HFD3_k127_5746598_4 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000008849 63.0
HFD3_k127_5803712_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 2.599e-204 662.0
HFD3_k127_5803712_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 600.0
HFD3_k127_5803712_2 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 533.0
HFD3_k127_5803712_3 PSP1 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000006557 239.0
HFD3_k127_5803712_4 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000001798 209.0
HFD3_k127_5803712_5 Curli production assembly/transport component CsgG - - - 0.00000000000000000000000000000000000000000008776 164.0
HFD3_k127_5803712_6 DNA polymerase III, delta subunit, C terminal K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000001307 174.0
HFD3_k127_5803712_7 - - - - 0.000000000000000000000000000001225 128.0
HFD3_k127_5820441_0 KaiB K08481 - - 0.00000000000000000000000000000000000007327 149.0
HFD3_k127_5820441_1 KaiB K08481 - - 0.000000000000000000000000000000007399 132.0
HFD3_k127_5820441_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000694 138.0
HFD3_k127_5820441_3 Pfam:KaiC K08482 - - 0.000000000000000000000007084 107.0
HFD3_k127_589269_0 PFAM natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009875 578.0
HFD3_k127_589269_1 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 419.0
HFD3_k127_589269_2 MgtE intracellular N domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 390.0
HFD3_k127_589269_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007289 347.0
HFD3_k127_589269_4 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006725 304.0
HFD3_k127_589269_5 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007139 298.0
HFD3_k127_589269_6 protein conserved in bacteria - - - 0.0005638 48.0
HFD3_k127_5906169_0 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 538.0
HFD3_k127_5906169_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000136 257.0
HFD3_k127_5906169_2 Glycosyltransferase family 10 (fucosyltransferase) C-term K20151 - 2.4.1.152,2.4.1.65 0.0000000000000000000000000000000000000000000000000000000000000000495 237.0
HFD3_k127_5906169_3 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000006347 222.0
HFD3_k127_5906169_4 PFAM glycosyl transferase family 9 K02841 - - 0.0000000000000000000000000000001562 128.0
HFD3_k127_6006612_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 1.338e-195 621.0
HFD3_k127_6006612_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008301 611.0
HFD3_k127_6006612_10 Acylphosphatase K01512 - 3.6.1.7 0.000000000000000000001167 96.0
HFD3_k127_6006612_11 AAA domain, putative AbiEii toxin, Type IV TA system K01996 - - 0.0000000000000000001229 88.0
HFD3_k127_6006612_12 Cytochrome c - - - 0.00000000000002467 85.0
HFD3_k127_6006612_13 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.0004424 45.0
HFD3_k127_6006612_2 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 492.0
HFD3_k127_6006612_3 Mo-co oxidoreductase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 419.0
HFD3_k127_6006612_4 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 401.0
HFD3_k127_6006612_5 PFAM Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 366.0
HFD3_k127_6006612_6 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 308.0
HFD3_k127_6006612_7 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000001024 260.0
HFD3_k127_6006612_8 PFAM Sulphate transporter K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004719 257.0
HFD3_k127_6006612_9 ABC transporter K01996 - - 0.000000000000000000000000000000379 123.0
HFD3_k127_6239897_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K21025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 411.0
HFD3_k127_6239897_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000003015 264.0
HFD3_k127_6239897_2 PFAM Colicin V production protein K03558 - - 0.000005602 56.0
HFD3_k127_6253645_0 Membrane protein, TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003743 320.0
HFD3_k127_6253645_1 MgtC family K07507 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001346 269.0
HFD3_k127_6253645_2 Probably functions as a manganese efflux pump - - - 0.0000000000000000000000000000000000000000000000000000000000002715 216.0
HFD3_k127_6253645_3 Glycine zipper - - - 0.00000000000000000000000000000000000003714 148.0
HFD3_k127_6253645_4 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.00000000000000000002201 93.0
HFD3_k127_6262143_0 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 9.464e-219 704.0
HFD3_k127_6262143_1 Alpha-2-Macroglobulin K06894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 614.0
HFD3_k127_6262143_2 SMART Elongator protein 3 MiaB NifB K22227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 553.0
HFD3_k127_6262143_3 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004759 472.0
HFD3_k127_6262143_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 419.0
HFD3_k127_6262143_5 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 336.0
HFD3_k127_6262143_6 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 301.0
HFD3_k127_6262143_7 - - - - 0.00000000000000000000000000000000000000000000000000000000009718 211.0
HFD3_k127_6262143_8 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000002632 159.0
HFD3_k127_6262143_9 Cupin 2 conserved barrel domain - - - 0.00000000000000000000000003285 112.0
HFD3_k127_6331082_0 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.0 1200.0
HFD3_k127_6331082_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 534.0
HFD3_k127_6331082_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 454.0
HFD3_k127_6331082_3 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 436.0
HFD3_k127_6331082_4 DRTGG domain K13788 - 2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000211 221.0
HFD3_k127_6331082_5 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.0000008322 52.0
HFD3_k127_6346009_0 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000296 499.0
HFD3_k127_6346009_1 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 460.0
HFD3_k127_6346009_2 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004688 292.0
HFD3_k127_6346009_3 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000139 214.0
HFD3_k127_6346009_4 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000003334 158.0
HFD3_k127_6346009_5 - - - - 0.0000000000001398 74.0
HFD3_k127_6390370_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.484e-218 706.0
HFD3_k127_6390370_1 Protein involved in outer membrane biogenesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004361 599.0
HFD3_k127_6390370_2 Branched-chain amino acid aminotransferase K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000043 458.0
HFD3_k127_6390370_3 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003427 386.0
HFD3_k127_6390370_4 ABC-2 type transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 350.0
HFD3_k127_6390370_5 chlorophyll binding K03286,K03640 - - 0.0000000000000000000000000000000000000000000000000000000009639 214.0
HFD3_k127_6390370_6 COG3284 Transcriptional activator of acetoin glycerol metabolism K21405 - - 0.0000000000000000000000000000000002805 144.0
HFD3_k127_6391177_0 4Fe-4S dicluster domain K00184 - - 0.0 1036.0
HFD3_k127_6391177_1 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 589.0
HFD3_k127_6391177_2 Vitamin K epoxide reductase family - - - 0.0000000000000000000000000000000000000000000000000000000002575 216.0
HFD3_k127_6391177_3 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000002269 201.0
HFD3_k127_6391177_4 Cytochrome c - - - 0.00000000000000000000000000000000001391 154.0
HFD3_k127_6391177_5 - - - - 0.000000000000649 68.0
HFD3_k127_6391177_6 Cytochrome c K00425,K07245,K08738 - 1.10.3.14 0.00000000004103 76.0
HFD3_k127_6395484_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1484.0
HFD3_k127_6395484_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.391e-270 844.0
HFD3_k127_6395484_10 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 411.0
HFD3_k127_6395484_11 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 374.0
HFD3_k127_6395484_12 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006491 370.0
HFD3_k127_6395484_13 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 355.0
HFD3_k127_6395484_14 radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 312.0
HFD3_k127_6395484_15 TIGRFAM signal peptidase I K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000004483 248.0
HFD3_k127_6395484_16 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000001016 233.0
HFD3_k127_6395484_17 Belongs to the purine pyrimidine phosphoribosyltransferase family. PyrR subfamily K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000003432 226.0
HFD3_k127_6395484_18 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000006614 229.0
HFD3_k127_6395484_19 Mur ligase, middle domain protein K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000005071 231.0
HFD3_k127_6395484_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 2.815e-207 665.0
HFD3_k127_6395484_20 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000003144 224.0
HFD3_k127_6395484_21 acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.000000000000000000000000000001605 124.0
HFD3_k127_6395484_22 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000005264 119.0
HFD3_k127_6395484_23 Plasmid stabilization system - - - 0.0000000000000000000003454 98.0
HFD3_k127_6395484_24 4 iron, 4 sulfur cluster binding K00176 - 1.2.7.3 0.000000000000000000003763 94.0
HFD3_k127_6395484_25 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 0.000000000000001145 78.0
HFD3_k127_6395484_26 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.00000000000002518 75.0
HFD3_k127_6395484_3 Aminotransferase class I and II K10206,K14261 GO:0003674,GO:0003824,GO:0004021,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0030632,GO:0032787,GO:0042851,GO:0042852,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0047635,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006065 574.0
HFD3_k127_6395484_4 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 526.0
HFD3_k127_6395484_5 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 483.0
HFD3_k127_6395484_6 Homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006604 481.0
HFD3_k127_6395484_7 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005031 458.0
HFD3_k127_6395484_8 Proposed homoserine kinase K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006355 437.0
HFD3_k127_6395484_9 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007644 418.0
HFD3_k127_6438960_0 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 8.592e-219 689.0
HFD3_k127_6438960_1 NADH-quinone oxidoreductase chain L K00341 - 1.6.5.3 2.144e-197 639.0
HFD3_k127_6438960_2 NAD binding K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009901 447.0
HFD3_k127_6438960_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007865 421.0
HFD3_k127_6438960_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000005575 227.0
HFD3_k127_6438960_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000005321 188.0
HFD3_k127_6438960_6 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.00000000000000000000000000000000001799 138.0
HFD3_k127_6438960_7 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000119 136.0
HFD3_k127_6438960_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000203 105.0
HFD3_k127_6438960_9 Protein conserved in bacteria K09986 - - 0.0000000000000007772 87.0
HFD3_k127_6505251_0 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005424 486.0
HFD3_k127_6505251_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 313.0
HFD3_k127_6505251_2 Thioredoxin domain - - - 0.000000000000000000000000001658 113.0
HFD3_k127_657400_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 2.896e-267 835.0
HFD3_k127_657400_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.726e-225 713.0
HFD3_k127_657400_2 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 1.893e-206 666.0
HFD3_k127_657400_3 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000519 416.0
HFD3_k127_657400_4 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000001232 192.0
HFD3_k127_657400_5 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000003379 177.0
HFD3_k127_657400_6 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000003555 171.0
HFD3_k127_6577810_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K00344,K00966,K01840,K03431,K15778,K16881 - 1.6.5.5,2.7.7.13,5.4.2.10,5.4.2.2,5.4.2.8 1.952e-285 899.0
HFD3_k127_6577810_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K12257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007269 511.0
HFD3_k127_6577810_10 LysE type translocator - - - 0.00000000000000000000000000000000000000000000000000007718 198.0
HFD3_k127_6577810_11 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000002788 177.0
HFD3_k127_6577810_12 PFAM Stage II sporulation K06381 - - 0.00000000000000000000000000000000000000000007095 182.0
HFD3_k127_6577810_13 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.000000000000000000000000005719 114.0
HFD3_k127_6577810_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 410.0
HFD3_k127_6577810_3 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 405.0
HFD3_k127_6577810_4 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 390.0
HFD3_k127_6577810_5 PFAM Band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 369.0
HFD3_k127_6577810_6 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 327.0
HFD3_k127_6577810_7 SMART PUA domain containing protein K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008248 301.0
HFD3_k127_6577810_8 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000003422 224.0
HFD3_k127_6577810_9 beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000003962 228.0
HFD3_k127_6597051_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005718 549.0
HFD3_k127_6597051_1 Fe-S oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 531.0
HFD3_k127_6597051_10 Domain of unknown function (DUF2437) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002502 277.0
HFD3_k127_6597051_11 4Fe-4S dicluster domain K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000001017 254.0
HFD3_k127_6597051_12 PFAM regulatory protein TetR K13770 - - 0.000000000000000000000000000000000000000000000000002532 189.0
HFD3_k127_6597051_13 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000001061 186.0
HFD3_k127_6597051_14 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000158 128.0
HFD3_k127_6597051_15 TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000003126 118.0
HFD3_k127_6597051_16 PFAM ADP-ribosylation Crystallin J1 - - - 0.0000000000000000000003689 111.0
HFD3_k127_6597051_2 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 512.0
HFD3_k127_6597051_3 FAD linked oxidase domain protein K00102,K00104 - 1.1.2.4,1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 488.0
HFD3_k127_6597051_4 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 466.0
HFD3_k127_6597051_5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 434.0
HFD3_k127_6597051_6 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 382.0
HFD3_k127_6597051_7 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 301.0
HFD3_k127_6597051_8 regulatory protein IclR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 294.0
HFD3_k127_6597051_9 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001165 290.0
HFD3_k127_6610720_0 AcrB/AcrD/AcrF family K03296,K18138 - - 0.0 1666.0
HFD3_k127_6610720_1 AcrB/AcrD/AcrF family K03296,K18138 - - 0.0 1653.0
HFD3_k127_6610720_10 Bacterial extracellular solute-binding protein K02027,K10236 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 525.0
HFD3_k127_6610720_11 HlyD family secretion protein K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003638 498.0
HFD3_k127_6610720_12 PFAM FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 500.0
HFD3_k127_6610720_13 HlyD family secretion protein K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 499.0
HFD3_k127_6610720_14 TOBE domain K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006916 376.0
HFD3_k127_6610720_15 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 357.0
HFD3_k127_6610720_16 glycerophosphodiester transmembrane transport K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 342.0
HFD3_k127_6610720_17 intracellular protease K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000000000009467 234.0
HFD3_k127_6610720_18 Flavin reductase like domain K00484,K16048 - 1.5.1.36 0.00000000000000000000001769 115.0
HFD3_k127_6610720_19 - - - - 0.0000000000000000000005277 102.0
HFD3_k127_6610720_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 1.486e-298 924.0
HFD3_k127_6610720_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 4.018e-274 854.0
HFD3_k127_6610720_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K11383 - 2.7.13.3 5.487e-224 710.0
HFD3_k127_6610720_5 PFAM response regulator receiver K11384 - - 1.055e-208 659.0
HFD3_k127_6610720_6 Major facilitator superfamily K08167 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 613.0
HFD3_k127_6610720_7 transcription factor binding K02584,K12146,K12266,K15836,K21009 GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 622.0
HFD3_k127_6610720_8 PFAM Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 563.0
HFD3_k127_6610720_9 PFAM Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 565.0
HFD3_k127_668593_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 371.0
HFD3_k127_668593_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004808 340.0
HFD3_k127_668593_10 dihydromethanopterin reductase activity - - - 0.00000000000000000002389 92.0
HFD3_k127_668593_2 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007988 334.0
HFD3_k127_668593_3 Peptidase family M50 K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000965 356.0
HFD3_k127_668593_4 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 301.0
HFD3_k127_668593_5 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000125 284.0
HFD3_k127_668593_6 Ribosome recycling factor K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000001964 206.0
HFD3_k127_668593_7 PFAM phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.00000000000000000000000000000000000000002727 162.0
HFD3_k127_668593_8 PFAM IS1 transposase K07480 - - 0.0000000000000000000000000000000000000342 143.0
HFD3_k127_668593_9 Glycoprotease family K14742 - - 0.00000000000000000000000000000000000003479 156.0
HFD3_k127_6729565_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 1.083e-306 972.0
HFD3_k127_6729565_1 Histidine kinase A domain protein K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003727 268.0
HFD3_k127_6729565_2 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000005361 226.0
HFD3_k127_6729565_3 Histidine kinase - - - 0.000000000000000009028 99.0
HFD3_k127_6729565_4 phosphorelay signal transduction system - - - 0.000004927 49.0
HFD3_k127_6762791_0 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006081 502.0
HFD3_k127_6762791_1 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008925 517.0
HFD3_k127_6762791_10 IMP dehydrogenase activity K04767 - - 0.00000000000000000000000000000000000000000001198 170.0
HFD3_k127_6762791_11 Nitroreductase family - - - 0.000000000000000000000000000000000004512 145.0
HFD3_k127_6762791_12 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.000000000000000000000000000005104 125.0
HFD3_k127_6762791_13 PFAM CBS domain - - - 0.00000000000000000000000000002712 132.0
HFD3_k127_6762791_14 PFAM nitrogen-fixing NifU domain protein - - - 0.00000000000000000000000002271 111.0
HFD3_k127_6762791_15 Nitrogen regulation K07712 - - 0.0000000000000002417 87.0
HFD3_k127_6762791_16 Ferredoxin - GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114 - 0.0000000000000006955 83.0
HFD3_k127_6762791_17 Tfp pilus assembly protein FimV - - - 0.0000000000001223 85.0
HFD3_k127_6762791_18 PFAM Rhodanese domain protein - - - 0.00001218 54.0
HFD3_k127_6762791_19 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0001659 47.0
HFD3_k127_6762791_2 Beta-eliminating lyase K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 441.0
HFD3_k127_6762791_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883,K15526 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16,6.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 402.0
HFD3_k127_6762791_4 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 304.0
HFD3_k127_6762791_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K14986 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001848 287.0
HFD3_k127_6762791_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002975 258.0
HFD3_k127_6762791_7 Dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000002863 218.0
HFD3_k127_6762791_8 assembly protein, NifU family K04488 - - 0.00000000000000000000000000000000000000000000000002923 198.0
HFD3_k127_6762791_9 DNA integration K14059 - - 0.00000000000000000000000000000000000000000000002644 179.0
HFD3_k127_6767854_0 Seven times multi-haem cytochrome CxxCH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 515.0
HFD3_k127_6767854_1 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 438.0
HFD3_k127_6767854_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 372.0
HFD3_k127_6767854_3 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00162,K00627 - 1.2.4.1,2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008678 354.0
HFD3_k127_6767854_4 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020,K00042,K18121 - 1.1.1.31,1.1.1.60,1.1.1.79 0.00000000000000000000000000000000000000000000000000000000000006223 226.0
HFD3_k127_6767854_5 Polypeptide deformylase K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000004788 199.0
HFD3_k127_6767854_6 helix_turn_helix, cAMP Regulatory protein K01420,K21563 - - 0.00000000000000000000000000000000000000000000000000004471 195.0
HFD3_k127_6767854_7 ACT domain K03567 - - 0.0000000000000000000000000000000000000000000000001005 184.0
HFD3_k127_6767854_8 TPR repeat K02656 - - 0.000000000002046 78.0
HFD3_k127_6782619_0 Curli production assembly/transport component CsgG - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 432.0
HFD3_k127_6782619_1 Putative bacterial lipoprotein (DUF799) - - - 0.00000000000000000000000000000000000000000000000000000000000000000007205 244.0
HFD3_k127_6782619_2 Domain of unknown function (DUF4810) - - - 0.0000000000000000000000000000003545 127.0
HFD3_k127_6782619_3 - - - - 0.00000000000000000000000006946 110.0
HFD3_k127_6782619_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000009856 98.0
HFD3_k127_6795117_0 4Fe-4S single cluster domain K03639,K20967 - 4.1.99.22,4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 329.0
HFD3_k127_6795117_1 ABC transporter K06857 - 3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000001629 244.0
HFD3_k127_6795117_2 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000009827 228.0
HFD3_k127_6795117_3 Probable molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000002373 187.0
HFD3_k127_6795117_4 Binding-protein-dependent transport system inner membrane component K05773 - - 0.0000000000000000000001017 97.0
HFD3_k127_6830801_0 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 6.085e-197 622.0
HFD3_k127_6830801_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679,K01744 - 4.2.1.2,4.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 529.0
HFD3_k127_6830801_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007527 288.0
HFD3_k127_6830801_3 cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000978 226.0
HFD3_k127_6830801_4 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000007602 209.0
HFD3_k127_6830801_5 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000000000000002331 117.0
HFD3_k127_6986259_0 COG0058 Glucan phosphorylase K00688 - 2.4.1.1 1.611e-292 922.0
HFD3_k127_6986259_1 Conserved carboxylase domain K01958 - 6.4.1.1 4.844e-228 734.0
HFD3_k127_6986259_10 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007961 391.0
HFD3_k127_6986259_11 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 390.0
HFD3_k127_6986259_12 PFAM ABC transporter transmembrane region K06147,K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009356 390.0
HFD3_k127_6986259_13 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 373.0
HFD3_k127_6986259_14 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 343.0
HFD3_k127_6986259_15 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 310.0
HFD3_k127_6986259_16 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006459 280.0
HFD3_k127_6986259_17 oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009544 275.0
HFD3_k127_6986259_18 Bacterial membrane protein, YfhO - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002425 280.0
HFD3_k127_6986259_19 TIGRFAM methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000111 228.0
HFD3_k127_6986259_2 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 572.0
HFD3_k127_6986259_20 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000003626 199.0
HFD3_k127_6986259_21 Uncharacterized BCR, COG1636 K03470,K09765 - 1.17.99.6,3.1.26.4 0.000000000000000000000000000000000000000000004814 173.0
HFD3_k127_6986259_22 Including oxidative damage repair enzymes - - - 0.0000000000000000000000000000000000005997 148.0
HFD3_k127_6986259_23 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000005881 143.0
HFD3_k127_6986259_24 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000008504 139.0
HFD3_k127_6986259_25 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000004037 119.0
HFD3_k127_6986259_26 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.0000000000000002741 86.0
HFD3_k127_6986259_28 - - - - 0.00001872 47.0
HFD3_k127_6986259_29 positive regulation of growth - - - 0.00004407 50.0
HFD3_k127_6986259_3 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006167 537.0
HFD3_k127_6986259_31 Phage integrase family - - - 0.0001992 49.0
HFD3_k127_6986259_4 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009707 531.0
HFD3_k127_6986259_5 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 520.0
HFD3_k127_6986259_6 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01959 - 6.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 502.0
HFD3_k127_6986259_7 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 484.0
HFD3_k127_6986259_8 ABC transporter transmembrane region K06147,K18890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 504.0
HFD3_k127_6986259_9 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 446.0
HFD3_k127_7004212_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 432.0
HFD3_k127_7004212_1 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008986 414.0
HFD3_k127_7004212_10 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000001266 163.0
HFD3_k127_7004212_11 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000003237 134.0
HFD3_k127_7004212_12 YGGT family K02221 - - 0.000000000000000000000000000004446 122.0
HFD3_k127_7004212_13 Essential cell division protein K03589 - - 0.0000000000000000000000000002382 124.0
HFD3_k127_7004212_14 - - - - 0.00000000000000000000000006375 113.0
HFD3_k127_7004212_15 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000001517 99.0
HFD3_k127_7004212_16 Belongs to the UPF0235 family K09131 - - 0.00000000000000000003594 97.0
HFD3_k127_7004212_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 410.0
HFD3_k127_7004212_3 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 363.0
HFD3_k127_7004212_4 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 369.0
HFD3_k127_7004212_5 Quinohemoprotein amine dehydrogenase, alpha subunit domain II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 323.0
HFD3_k127_7004212_6 Enoyl-(Acyl carrier protein) reductase K00059,K00068 - 1.1.1.100,1.1.1.140 0.00000000000000000000000000000000000000000000000000000000000000000000001141 253.0
HFD3_k127_7004212_7 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000002477 218.0
HFD3_k127_7004212_8 Belongs to the pyrroline-5-carboxylate reductase family K00286 GO:0003674,GO:0003824,GO:0004735,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009651,GO:0016491,GO:0016645,GO:0016646,GO:0030312,GO:0044424,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.5.1.2 0.00000000000000000000000000000000000000000000000000000002874 211.0
HFD3_k127_7004212_9 Maf-like protein K06287 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000006191 170.0
HFD3_k127_7004819_0 aconitate hydratase K01681 - 4.2.1.3 0.0 1192.0
HFD3_k127_7004819_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.0 1094.0
HFD3_k127_7004819_10 PFAM 4Fe-4S K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005032 496.0
HFD3_k127_7004819_11 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 512.0
HFD3_k127_7004819_12 3-beta hydroxysteroid dehydrogenase/isomerase family K10011,K12449 - 1.1.1.305,2.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 472.0
HFD3_k127_7004819_13 PFAM 2-nitropropane dioxygenase NPD K00459,K02371 - 1.13.12.16,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 440.0
HFD3_k127_7004819_14 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K01810,K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 385.0
HFD3_k127_7004819_15 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007388 385.0
HFD3_k127_7004819_16 4Fe-4S binding domain K08358 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 376.0
HFD3_k127_7004819_17 PFAM glycosyl transferase family 39 K07264 - 2.4.2.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006802 378.0
HFD3_k127_7004819_18 ATP-binding region, ATPase domain protein domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 387.0
HFD3_k127_7004819_19 PFAM Integral membrane protein TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 353.0
HFD3_k127_7004819_2 1,4-alpha-glucan branching enzyme activity K00700,K01236 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18,3.2.1.141 0.0 1032.0
HFD3_k127_7004819_20 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K04013,K15876 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006423 330.0
HFD3_k127_7004819_21 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 326.0
HFD3_k127_7004819_22 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 342.0
HFD3_k127_7004819_23 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 345.0
HFD3_k127_7004819_24 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 306.0
HFD3_k127_7004819_25 Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides K01784,K10011 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006040,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016741,GO:0016742,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0022607,GO:0033319,GO:0033320,GO:0034214,GO:0034641,GO:0034654,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046349,GO:0046483,GO:0046677,GO:0048037,GO:0048040,GO:0050662,GO:0050896,GO:0051259,GO:0051287,GO:0055086,GO:0055114,GO:0065003,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:0099618,GO:0099619,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:2001313,GO:2001315 1.1.1.305,2.1.2.13,5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006789 312.0
HFD3_k127_7004819_26 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 304.0
HFD3_k127_7004819_27 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 311.0
HFD3_k127_7004819_28 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 293.0
HFD3_k127_7004819_29 Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006863 257.0
HFD3_k127_7004819_3 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 3.118e-259 815.0
HFD3_k127_7004819_30 TRAP transporter T-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002367 263.0
HFD3_k127_7004819_31 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002799 253.0
HFD3_k127_7004819_32 Signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000484 246.0
HFD3_k127_7004819_33 Probably functions as a manganese efflux pump - - - 0.00000000000000000000000000000000000000000000000000000000000001114 220.0
HFD3_k127_7004819_34 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000003414 207.0
HFD3_k127_7004819_35 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000562 201.0
HFD3_k127_7004819_36 PFAM filamentation induced by cAMP protein Fic - - - 0.00000000000000000000000000000000000000000000005319 183.0
HFD3_k127_7004819_37 DoxX K15977 - - 0.0000000000000000000000000000000000000000004151 163.0
HFD3_k127_7004819_38 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.000000000000000000000000000000000000000002246 177.0
HFD3_k127_7004819_39 - - - - 0.00000000000000000000000000000000000006374 160.0
HFD3_k127_7004819_4 GTP-binding protein TypA K06207 - - 3.894e-252 796.0
HFD3_k127_7004819_40 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000003139 147.0
HFD3_k127_7004819_41 PFAM ROSMUCR transcriptional regulator - - - 0.0000000000000000000000000000002426 128.0
HFD3_k127_7004819_42 domain protein - - - 0.00000000000000000000000000000242 132.0
HFD3_k127_7004819_43 Two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.00000000000000000000000005729 114.0
HFD3_k127_7004819_44 CBS domain K04767 - - 0.0000000000000000000000003974 116.0
HFD3_k127_7004819_45 PFAM Phosphoglycerate mutase K08296 - - 0.000000000000000000007573 98.0
HFD3_k127_7004819_46 Calcineurin-like phosphoesterase - - - 0.00000000000000000003892 100.0
HFD3_k127_7004819_47 - - - - 0.000000000000000003075 87.0
HFD3_k127_7004819_48 Rubrerythrin - - - 0.0000003437 59.0
HFD3_k127_7004819_5 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 1.546e-236 741.0
HFD3_k127_7004819_6 PFAM Polysulphide reductase, NrfD K00185 - - 3.183e-215 679.0
HFD3_k127_7004819_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007942 565.0
HFD3_k127_7004819_8 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 515.0
HFD3_k127_7004819_9 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 511.0
HFD3_k127_7015363_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 593.0
HFD3_k127_7015363_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 565.0
HFD3_k127_7015363_2 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009713 536.0
HFD3_k127_7015363_3 COGs COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002738 296.0
HFD3_k127_7015363_4 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000004156 251.0
HFD3_k127_7015363_5 phosphotransferase related to Ser Thr protein kinases K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000001242 183.0
HFD3_k127_7015363_6 Nucleotidyl transferase K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000001482 182.0
HFD3_k127_7015363_7 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000001271 169.0
HFD3_k127_7015363_8 transglycosylase K08309 - - 0.0000000000000000000000001799 124.0
HFD3_k127_7015363_9 Xylose isomerase-like TIM barrel - - - 0.00000000000000000001024 102.0
HFD3_k127_70764_0 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 598.0
HFD3_k127_70764_1 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 485.0
HFD3_k127_70764_2 metal-dependent phosphohydrolase HD region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006685 374.0
HFD3_k127_70764_3 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000001613 246.0
HFD3_k127_70764_4 Secreted repeat of unknown function - - - 0.000000000000000000000000000000000000000003728 158.0
HFD3_k127_70764_5 LemA family K03744 - - 0.000000000000000000000000000000001551 131.0
HFD3_k127_7121805_0 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009681 361.0
HFD3_k127_7121805_1 4-hydroxyphenylacetate 3-hydroxylase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 334.0
HFD3_k127_7121805_3 Stage II sporulation protein M K06384 - - 0.0000000000000001815 93.0
HFD3_k127_7124460_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000006496 253.0
HFD3_k127_7124460_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000005994 198.0
HFD3_k127_7124460_2 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000000000000003416 166.0
HFD3_k127_7124460_3 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000817 149.0
HFD3_k127_71362_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 410.0
HFD3_k127_71362_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000005221 214.0
HFD3_k127_71362_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000006502 126.0
HFD3_k127_71362_3 domain, Protein - - - 0.0000000000000002436 86.0
HFD3_k127_7161170_0 O-methyltransferase activity - - - 9.438e-236 747.0
HFD3_k127_7161170_1 Belongs to the peptidase M16 family K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 624.0
HFD3_k127_7161170_10 Nucleoside recognition - - - 0.0000000000000000000000000003046 121.0
HFD3_k127_7161170_11 Nucleoside recognition - - - 0.0000000000000000000000324 113.0
HFD3_k127_7161170_12 Protein of unknown function (DUF2889) - - - 0.0009893 51.0
HFD3_k127_7161170_2 peptidase M29 K19689 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 335.0
HFD3_k127_7161170_3 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 329.0
HFD3_k127_7161170_4 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000553 286.0
HFD3_k127_7161170_5 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001404 269.0
HFD3_k127_7161170_6 HAD-superfamily hydrolase subfamily IA, variant 3 K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000573 246.0
HFD3_k127_7161170_7 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000004034 248.0
HFD3_k127_7161170_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000002302 238.0
HFD3_k127_7161170_9 protein possibly involved in aromatic compounds catabolism - - - 0.00000000000000000000000000000000000000000000001864 176.0
HFD3_k127_7179539_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 2.014e-253 811.0
HFD3_k127_7179539_1 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000006603 219.0
HFD3_k127_7179539_2 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000000000002131 196.0
HFD3_k127_7179539_3 RNA signal recognition particle 4.5S RNA - - - 0.0000000000000000000000000000000000000000000000000000006929 195.0
HFD3_k127_7179539_4 YCII-related domain - - - 0.00000000001376 66.0
HFD3_k127_7229813_0 PFAM response regulator receiver K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 552.0
HFD3_k127_7229813_1 Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009164 477.0
HFD3_k127_7229813_10 Glycine cleavage H-protein - - - 0.00000000000000000000000006524 118.0
HFD3_k127_7229813_11 Glycine cleavage H-protein - - - 0.0000000000000000000000004557 114.0
HFD3_k127_7229813_13 General secretion pathway protein C K02452 - - 0.0000000000001697 81.0
HFD3_k127_7229813_2 Type II and III secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 438.0
HFD3_k127_7229813_3 HAMP domain K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 407.0
HFD3_k127_7229813_4 4Fe-4S dicluster domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009616 315.0
HFD3_k127_7229813_5 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000000001366 194.0
HFD3_k127_7229813_6 Glycine cleavage H-protein - - - 0.000000000000000000000000000000000000000000000076 177.0
HFD3_k127_7229813_7 metallopeptidase activity K06974 - - 0.0000000000000000000000000000000000000004961 154.0
HFD3_k127_7229813_8 PFAM Type II secretion system protein E K02454 - - 0.000000000000000000000000000000000123 140.0
HFD3_k127_7229813_9 Transcription factor zinc-finger K09981 - - 0.0000000000000000000000000002476 117.0
HFD3_k127_7236697_0 NUDIX domain K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 325.0
HFD3_k127_7236697_1 dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003881 250.0
HFD3_k127_7236697_2 Pfam:Pyridox_oxidase - - - 0.000000000000000000000000000000003378 136.0
HFD3_k127_7236697_3 Rhodanese Homology Domain - - - 0.000000000000000000000000000002722 124.0
HFD3_k127_7236697_4 ferroxidase activity K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.00004754 45.0
HFD3_k127_7246267_0 Domain of unknown function (DUF4105) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005476 502.0
HFD3_k127_7246267_1 Protein of unknown function (DUF3015) - - - 0.000000000000000000000000000000001644 132.0
HFD3_k127_7255289_0 ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006571 364.0
HFD3_k127_7255289_1 Peptidase family U32 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 298.0
HFD3_k127_7255289_2 Radical SAM superfamily K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003044 285.0
HFD3_k127_7255289_3 Protein of unknown function (DUF1329) - - - 0.000000000000000000000000000000000001733 143.0
HFD3_k127_7255289_4 Subtilase family - - - 0.0000000000000000000000000000000003104 141.0
HFD3_k127_7255289_5 Quinohemoprotein amine dehydrogenase - - - 0.000000000000000000000000005948 124.0
HFD3_k127_7255289_6 peptidase U32 - - - 0.0000000000000000000000003113 118.0
HFD3_k127_7255289_7 Quinohemoprotein amine dehydrogenase, gamma subunit - - - 0.00000000000000000000007801 105.0
HFD3_k127_7360866_0 AMP-binding enzyme C-terminal domain K08295 - 6.2.1.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001358 283.0
HFD3_k127_7360866_1 Pfam:UPF0118 - - - 0.0000000000000000000000000000000000000000000000000000000001027 218.0
HFD3_k127_7360866_2 heat shock protein binding K03686,K04082,K05516 - - 0.00000000001192 70.0
HFD3_k127_7395845_0 Berberine and berberine like - - - 9.509e-228 715.0
HFD3_k127_7395845_1 PFAM Fatty acid hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 345.0
HFD3_k127_7395845_2 uridine phosphorylase activity K00757 - 2.4.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 335.0
HFD3_k127_7395845_3 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000005325 207.0
HFD3_k127_7395845_4 PFAM YbaK prolyl-tRNA synthetases associated domain - - - 0.00000000000000000000000005218 122.0
HFD3_k127_7469339_0 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 514.0
HFD3_k127_7469339_1 PFAM Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 450.0
HFD3_k127_7469339_10 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000001946 128.0
HFD3_k127_7469339_11 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000007392 131.0
HFD3_k127_7469339_12 - - - - 0.0000000000000000000000009236 114.0
HFD3_k127_7469339_13 HD domain - - - 0.000000000000000000003336 107.0
HFD3_k127_7469339_14 cellular modified histidine biosynthetic process - - - 0.00000000000000000003892 100.0
HFD3_k127_7469339_15 Putative regulatory protein - - - 0.00000000000227 70.0
HFD3_k127_7469339_2 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009334 344.0
HFD3_k127_7469339_3 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 375.0
HFD3_k127_7469339_4 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005949 291.0
HFD3_k127_7469339_5 Calcineurin-like phosphoesterase K07096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003796 287.0
HFD3_k127_7469339_6 Cytochrome c K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001722 285.0
HFD3_k127_7469339_7 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000004124 274.0
HFD3_k127_7469339_8 Pfam Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001218 267.0
HFD3_k127_7469339_9 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000001159 226.0
HFD3_k127_7499163_0 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase - - - 2.362e-199 633.0
HFD3_k127_7499163_1 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009645 321.0
HFD3_k127_7499163_2 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000001251 241.0
HFD3_k127_7499163_4 BON domain - - - 0.0000000000000000000000000000000499 129.0
HFD3_k127_7499163_5 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000002197 54.0
HFD3_k127_7499163_6 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.00004633 46.0
HFD3_k127_7570457_0 TRAP transporter solute receptor TAXI family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 598.0
HFD3_k127_7570457_1 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000001796 225.0
HFD3_k127_7570457_2 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000005831 198.0
HFD3_k127_7643734_0 Major Facilitator Superfamily K02575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006138 510.0
HFD3_k127_7643734_1 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002645 291.0
HFD3_k127_7643734_2 recombinase XerD K04763 GO:0000150,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009314,GO:0009628,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0071139,GO:0071704,GO:0090304,GO:0140097,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000003886 256.0
HFD3_k127_7643734_3 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.00000000002754 63.0
HFD3_k127_7754282_0 Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 2.489e-226 713.0
HFD3_k127_7754282_1 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 379.0
HFD3_k127_7754282_2 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002035 284.0
HFD3_k127_7754282_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000001113 227.0
HFD3_k127_7754282_4 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.0000000000000000000000000000000000000000000000000005772 185.0
HFD3_k127_7754282_5 Crp-like helix-turn-helix domain K10914 - - 0.0000000000000000001501 93.0
HFD3_k127_776969_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0 1245.0
HFD3_k127_776969_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 5e-323 1005.0
HFD3_k127_776969_10 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001129 256.0
HFD3_k127_776969_11 Nitrogen fixation master sensor histidine kinase, PAS domain-containing K02668,K07708,K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000206 193.0
HFD3_k127_776969_12 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K13053,K14160 - - 0.00000000000000000000000000000000000000000000000007626 194.0
HFD3_k127_776969_13 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000001856 177.0
HFD3_k127_776969_14 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000009122 158.0
HFD3_k127_776969_15 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000000002355 153.0
HFD3_k127_776969_16 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000008464 160.0
HFD3_k127_776969_17 Single-strand binding protein family K03111 - - 0.00000000000000000000000000000000000001001 148.0
HFD3_k127_776969_18 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000002912 147.0
HFD3_k127_776969_19 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000002041 140.0
HFD3_k127_776969_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 9.863e-319 1012.0
HFD3_k127_776969_20 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000001393 103.0
HFD3_k127_776969_21 PIN domain - - - 0.00000000000000000000004634 105.0
HFD3_k127_776969_22 Protein of unknown function (DUF3047) - - - 0.00000000000000001475 84.0
HFD3_k127_776969_23 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000001689 85.0
HFD3_k127_776969_24 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.000000000000001986 78.0
HFD3_k127_776969_25 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.00000001568 66.0
HFD3_k127_776969_26 - - - - 0.000002438 49.0
HFD3_k127_776969_3 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 4.871e-288 910.0
HFD3_k127_776969_4 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000591 527.0
HFD3_k127_776969_5 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 428.0
HFD3_k127_776969_6 response regulator K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 399.0
HFD3_k127_776969_7 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 380.0
HFD3_k127_776969_8 carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 313.0
HFD3_k127_776969_9 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000006971 261.0
HFD3_k127_796354_0 H( )-stimulated, divalent metal cation uptake system K03322 - - 2.311e-227 725.0
HFD3_k127_796354_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 1.161e-212 681.0
HFD3_k127_796354_2 Sigma-54 interaction domain K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 440.0
HFD3_k127_796354_3 glucose sorbosone K00117 - 1.1.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 431.0
HFD3_k127_796354_4 HlyD family secretion protein K07798,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 358.0
HFD3_k127_796354_5 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002545 271.0
HFD3_k127_796354_6 Domains HisKA, HATPase_c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004081 258.0
HFD3_k127_796354_7 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000001267 237.0
HFD3_k127_796354_8 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000002928 220.0
HFD3_k127_796354_9 Predicted membrane protein (DUF2318) - - - 0.00000000000000000000000000000001039 138.0
HFD3_k127_79874_0 helix_turn_helix, Lux Regulon K03556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 464.0
HFD3_k127_79874_1 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.000000000000000000000000000000000000001192 151.0
HFD3_k127_79874_2 RF-1 domain K15034 - - 0.00000002262 55.0
HFD3_k127_813824_0 Translation-initiation factor 2 K02519 - - 5.131e-236 755.0
HFD3_k127_813824_1 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 445.0
HFD3_k127_813824_10 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000001697 117.0
HFD3_k127_813824_11 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000001459 91.0
HFD3_k127_813824_12 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000000001499 92.0
HFD3_k127_813824_13 Protein of unknown function (DUF503) K09764 - - 0.000000000001815 71.0
HFD3_k127_813824_14 Protein of unknown function (DUF448) K07742 - - 0.0000003541 63.0
HFD3_k127_813824_2 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004154 427.0
HFD3_k127_813824_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648,K18003 - 2.3.1.180,2.3.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 395.0
HFD3_k127_813824_4 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 371.0
HFD3_k127_813824_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 302.0
HFD3_k127_813824_6 Arginase family K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000151 280.0
HFD3_k127_813824_7 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000001214 258.0
HFD3_k127_813824_8 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.00000000000000000000000000000000000000001836 166.0
HFD3_k127_813824_9 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000000000000000000000000428 133.0
HFD3_k127_820266_0 Belongs to the PEP-utilizing enzyme family K01006,K22424 - 2.7.3.13,2.7.9.1 0.0 1114.0
HFD3_k127_820266_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007813 623.0
HFD3_k127_820266_10 YmdB-like protein K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 291.0
HFD3_k127_820266_11 sodium-dependent phosphate transmembrane transporter activity K03324 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000558 292.0
HFD3_k127_820266_12 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000002849 230.0
HFD3_k127_820266_13 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000002996 211.0
HFD3_k127_820266_14 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000001939 137.0
HFD3_k127_820266_15 - - - - 0.00000000000000000000000001596 109.0
HFD3_k127_820266_16 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000006103 107.0
HFD3_k127_820266_17 Tetratricopeptide repeat - - - 0.0000000000000000000001068 113.0
HFD3_k127_820266_18 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000008205 90.0
HFD3_k127_820266_19 Domain of unknown function (DUF4115) K15539 - - 0.00000000001124 78.0
HFD3_k127_820266_2 Domain of unknown function (DUF3552) K18682 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 600.0
HFD3_k127_820266_20 - - - - 0.000000002355 63.0
HFD3_k127_820266_3 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 627.0
HFD3_k127_820266_4 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 511.0
HFD3_k127_820266_5 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 485.0
HFD3_k127_820266_6 PFAM thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 385.0
HFD3_k127_820266_7 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004432 380.0
HFD3_k127_820266_8 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005979 349.0
HFD3_k127_820266_9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 319.0
HFD3_k127_845270_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 481.0
HFD3_k127_845270_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 460.0
HFD3_k127_845270_10 RDD family - - - 0.00000000000000000000000203 108.0
HFD3_k127_845270_11 Cell surface protein - - - 0.00000000000000000000000292 120.0
HFD3_k127_845270_12 SpoVT / AbrB like domain - - - 0.0000000000000000000005473 96.0
HFD3_k127_845270_13 NADPH-dependent FMN reductase K19784 - - 0.00000000621 56.0
HFD3_k127_845270_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 453.0
HFD3_k127_845270_3 Mur ligase family, catalytic domain K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 437.0
HFD3_k127_845270_4 Peptidase dimerisation domain K12941 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008599 376.0
HFD3_k127_845270_5 LD-carboxypeptidase K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000003026 213.0
HFD3_k127_845270_6 Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.0000000000000000000000000000000000000000000000000001097 211.0
HFD3_k127_845270_7 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000001507 182.0
HFD3_k127_845270_8 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000001878 196.0
HFD3_k127_845270_9 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000000000000000009488 156.0
HFD3_k127_845794_0 Bacterial DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1159.0
HFD3_k127_845794_1 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 5.082e-213 672.0
HFD3_k127_845794_10 - - - - 0.00000001306 63.0
HFD3_k127_845794_11 Virulence factor BrkB K07058 - - 0.00007733 56.0
HFD3_k127_845794_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 384.0
HFD3_k127_845794_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009814 363.0
HFD3_k127_845794_4 Ferrous iron transport protein B K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 346.0
HFD3_k127_845794_5 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001742 306.0
HFD3_k127_845794_6 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004958 279.0
HFD3_k127_845794_7 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000001835 170.0
HFD3_k127_845794_8 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000003654 153.0
HFD3_k127_845794_9 - - - - 0.0000000000000000000000000000191 131.0
HFD3_k127_849843_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1176.0
HFD3_k127_849843_1 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 524.0
HFD3_k127_849843_10 Protein of unknown function (DUF2384) - - - 0.0000000000000000000000000005946 119.0
HFD3_k127_849843_11 GIY-YIG catalytic domain K07461 - - 0.000000000000000000001221 97.0
HFD3_k127_849843_12 Protein of unknown function (DUF507) - - - 0.000000000000000001592 90.0
HFD3_k127_849843_14 Protein of unknown function (DUF507) - - - 0.00001266 56.0
HFD3_k127_849843_2 NeuB family K03856,K04516 - 2.5.1.54,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 469.0
HFD3_k127_849843_3 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 329.0
HFD3_k127_849843_4 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 329.0
HFD3_k127_849843_5 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008221 291.0
HFD3_k127_849843_6 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000142 249.0
HFD3_k127_849843_7 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.00000000000000000000000000000000000000181 150.0
HFD3_k127_849843_8 RES - - - 0.000000000000000000000000000000000005004 149.0
HFD3_k127_849843_9 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000008 141.0
HFD3_k127_853513_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000168 164.0
HFD3_k127_853513_1 Class III cytochrome C family - - - 0.00000000000003634 82.0
HFD3_k127_863890_0 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 578.0
HFD3_k127_864037_0 sigma factor activity K03088 - - 8.424e-197 621.0
HFD3_k127_864037_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001651 255.0
HFD3_k127_864037_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000169 255.0
HFD3_k127_864037_3 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008187 244.0
HFD3_k127_864037_4 nadph quinone oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000001386 211.0
HFD3_k127_864037_5 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000000000001609 200.0
HFD3_k127_864037_6 RNA signal recognition particle 4.5S RNA - - - 0.00000000000000000000000000000000000000000000000000009933 189.0
HFD3_k127_864037_7 YCII-related domain - - - 0.00000000000000000000000000000000000000000000000003712 183.0
HFD3_k127_864037_8 PFAM DGPFAETKE family protein - - - 0.0000000000000000000000000000000000000000000000001433 183.0
HFD3_k127_882327_0 Type II secretion system (T2SS), protein K K02460 - - 0.000000001619 63.0
HFD3_k127_887276_0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000003483 237.0
HFD3_k127_887276_1 Belongs to the pseudouridine synthase RluA family K06180 - 5.4.99.23 0.00000000000000000000000000007527 128.0
HFD3_k127_887276_2 Universal stress protein family - - - 0.0000000000000000000003653 106.0
HFD3_k127_887276_3 PFAM outer membrane efflux protein - - - 0.000000000000000000000375 105.0
HFD3_k127_909635_0 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006638 468.0
HFD3_k127_909635_1 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000428 428.0
HFD3_k127_909635_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 330.0
HFD3_k127_909635_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008044 298.0
HFD3_k127_909635_4 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000001924 204.0
HFD3_k127_909635_5 Cytochrome c - - - 0.000000000000000000000000000000000000000001597 173.0
HFD3_k127_909635_6 AraC-like ligand binding domain - - - 0.00000000000000000000000005211 111.0
HFD3_k127_909635_7 2-Nitropropane dioxygenase - - - 0.0000000000000007524 83.0
HFD3_k127_910014_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 9.847e-200 642.0
HFD3_k127_910014_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006957 401.0
HFD3_k127_910301_0 PFAM Glu Leu Phe Val dehydrogenase K15371 - 1.4.1.2 0.0 1265.0
HFD3_k127_910301_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.238e-303 960.0
HFD3_k127_910301_10 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 332.0
HFD3_k127_910301_11 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 313.0
HFD3_k127_910301_12 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 305.0
HFD3_k127_910301_13 Belongs to the LarC family K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008733 311.0
HFD3_k127_910301_14 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008771 295.0
HFD3_k127_910301_15 transmembrane transport K16052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005428 302.0
HFD3_k127_910301_16 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008173 292.0
HFD3_k127_910301_17 L,D-transpeptidase catalytic domain K16291 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001654 275.0
HFD3_k127_910301_18 Transporter associated domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005329 267.0
HFD3_k127_910301_19 Transporter associated domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000003594 263.0
HFD3_k127_910301_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 512.0
HFD3_k127_910301_20 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000001615 246.0
HFD3_k127_910301_21 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000473 230.0
HFD3_k127_910301_22 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000003353 207.0
HFD3_k127_910301_23 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000001914 204.0
HFD3_k127_910301_24 regulatory protein TetR - - - 0.000000000000000000000000000000000000000000000000002194 188.0
HFD3_k127_910301_25 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000001043 175.0
HFD3_k127_910301_26 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000004623 169.0
HFD3_k127_910301_27 PFAM Cytochrome c, class I - - - 0.000000000000000000000000000000000000106 146.0
HFD3_k127_910301_28 COG1226 Kef-type K transport systems - - - 0.0000000000000000000000000000000003427 142.0
HFD3_k127_910301_29 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000000000000000007814 129.0
HFD3_k127_910301_3 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006267 488.0
HFD3_k127_910301_30 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000004849 111.0
HFD3_k127_910301_31 CGNR zinc finger - - - 0.0000000000000000000000006148 112.0
HFD3_k127_910301_32 Belongs to the universal stress protein A family - - - 0.0000000000000002687 86.0
HFD3_k127_910301_33 Receptor family ligand binding region K01999 - - 0.000000000003344 81.0
HFD3_k127_910301_34 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000006356 78.0
HFD3_k127_910301_36 deaminase K01485 - 3.5.4.1 0.0000005898 53.0
HFD3_k127_910301_37 - - - - 0.0001145 48.0
HFD3_k127_910301_38 Helix-turn-helix XRE-family like proteins - - - 0.0001872 48.0
HFD3_k127_910301_4 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 483.0
HFD3_k127_910301_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 484.0
HFD3_k127_910301_6 SMART helicase c2 K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009074 471.0
HFD3_k127_910301_7 Fic/DOC family N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004116 454.0
HFD3_k127_910301_8 DnaJ central domain K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 430.0
HFD3_k127_910301_9 PFAM Radical SAM K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 352.0
HFD3_k127_921383_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 2.608e-217 694.0
HFD3_k127_921383_1 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 2.167e-206 663.0
HFD3_k127_921383_10 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001902 264.0
HFD3_k127_921383_11 Polyprenyl synthetase K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000001734 246.0
HFD3_k127_921383_12 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000000000000000000005971 253.0
HFD3_k127_921383_13 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000002289 233.0
HFD3_k127_921383_14 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000001443 231.0
HFD3_k127_921383_15 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000002033 199.0
HFD3_k127_921383_16 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000002116 147.0
HFD3_k127_921383_17 peroxiredoxin activity - - - 0.000000000000000000000000000000000000583 153.0
HFD3_k127_921383_18 protein conserved in bacteria K09798 - - 0.000000000000000000000000000001802 132.0
HFD3_k127_921383_19 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000004853 132.0
HFD3_k127_921383_2 Bacterial membrane protein, YfhO - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 535.0
HFD3_k127_921383_20 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000001386 106.0
HFD3_k127_921383_21 - - - - 0.0000000000000000000005428 105.0
HFD3_k127_921383_22 Type III secretion system lipoprotein chaperone (YscW) K09914 - - 0.0000000000000000017 93.0
HFD3_k127_921383_23 ATPases associated with a variety of cellular activities - - - 0.00000000000000007276 89.0
HFD3_k127_921383_24 Peptidase family M23 K21471 - - 0.00000000000002508 87.0
HFD3_k127_921383_25 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000002127 72.0
HFD3_k127_921383_26 Ubiquinone biosynthesis O-methyltransferase - - - 0.0000000000273 76.0
HFD3_k127_921383_27 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000004804 70.0
HFD3_k127_921383_28 May be involved in cell division K05803 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009987,GO:0016020,GO:0030674,GO:0044464,GO:0051301,GO:0060090,GO:0071944 - 0.000003565 60.0
HFD3_k127_921383_29 peptidyl-prolyl cis-trans isomerase activity K03769,K03771 - 5.2.1.8 0.000006379 58.0
HFD3_k127_921383_3 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009364 486.0
HFD3_k127_921383_30 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation K09811 - - 0.00001172 58.0
HFD3_k127_921383_32 peptidyl-prolyl isomerase K03769 - 5.2.1.8 0.0001884 53.0
HFD3_k127_921383_4 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008046 447.0
HFD3_k127_921383_5 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009843 445.0
HFD3_k127_921383_6 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007368 449.0
HFD3_k127_921383_7 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009382 407.0
HFD3_k127_921383_8 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 347.0
HFD3_k127_921383_9 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003858 307.0
HFD3_k127_927265_0 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01738,K01883,K12339 - 2.5.1.47,6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 448.0
HFD3_k127_927265_1 PFAM Cys Met metabolism K01739,K01760 - 2.5.1.48,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008909 419.0
HFD3_k127_927265_10 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K16168 - - 0.0000000000000000000008254 95.0
HFD3_k127_927265_11 - K07245 - - 0.000000002796 64.0
HFD3_k127_927265_12 Belongs to the sulfur carrier protein TusA family - - - 0.000000005663 66.0
HFD3_k127_927265_13 - - - - 0.0000002962 58.0
HFD3_k127_927265_2 nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008672 322.0
HFD3_k127_927265_3 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 301.0
HFD3_k127_927265_4 Belongs to the ABC transporter superfamily K02052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001164 299.0
HFD3_k127_927265_5 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000005445 249.0
HFD3_k127_927265_6 Extracellular solute-binding protein K02048 - - 0.0000000000000000000000000000000000000000000000000000000000000008253 231.0
HFD3_k127_927265_7 sulfate transport system, permease K02047 - - 0.000000000000000000000000000000000000000000000000004361 194.0
HFD3_k127_927265_8 - - - - 0.000000000000000000000000001106 121.0
HFD3_k127_927265_9 Transcriptional regulator - - - 0.00000000000000000000000003145 113.0