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Overview

ID MAG01684
Name HFD3_bin.24
Sample SMP0045
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Blastocatellia
Order UBA7656
Family UBA7656
Genus JBFMDH01
Species
Assembly information
Completeness (%) 75.64
Contamination (%) 1.64
GC content (%) 52.0
N50 (bp) 3,572
Genome size (bp) 5,629,203

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes4734

Gene name Description KEGG GOs EC E-value Score Sequence
HFD3_k127_1000876_0 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000428 323.0
HFD3_k127_1000876_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00007893 54.0
HFD3_k127_1009433_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 344.0
HFD3_k127_1009433_1 Predicted Zn-dependent protease (DUF2268) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002076 279.0
HFD3_k127_1009433_2 Ankyrin repeat K06867 - - 0.0000000000001386 78.0
HFD3_k127_1011373_0 NurA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 328.0
HFD3_k127_1011373_1 PFAM ADP-ribosylglycohydrolase K05521 - 3.2.2.24 0.000000000000000000000000000000000000000000000000000000000000000001512 231.0
HFD3_k127_1011373_2 23S rRNA-intervening sequence protein - - - 0.0000000002899 61.0
HFD3_k127_1016101_0 GAF domain - - - 0.000000001051 70.0
HFD3_k127_1018240_0 hydrolase, family 65, central catalytic K15923 - 3.2.1.51 5.897e-199 631.0
HFD3_k127_1018240_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003125 287.0
HFD3_k127_1018240_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000001879 257.0
HFD3_k127_1019406_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 367.0
HFD3_k127_1019772_0 PFAM type I phosphodiesterase nucleotide pyrophosphatase K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000001153 235.0
HFD3_k127_1022136_0 Associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 390.0
HFD3_k127_1022136_1 - - - - 0.0000000000000000000000000000000000000000000002363 173.0
HFD3_k127_1022136_2 DinB superfamily - - - 0.00000000000000000455 90.0
HFD3_k127_1024450_0 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000172 292.0
HFD3_k127_1024450_1 LexA-binding, inner membrane-associated putative hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000003409 219.0
HFD3_k127_1024450_2 CARDB - - - 0.000000000000000000000000000000000000000000000000000000000005828 223.0
HFD3_k127_1024450_3 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000006659 202.0
HFD3_k127_1024450_5 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000000000000000000000000000000004988 144.0
HFD3_k127_1024450_6 - - - - 0.000000000000000000004975 103.0
HFD3_k127_1024450_7 - - - - 0.000000000000002759 83.0
HFD3_k127_1024450_8 tetratricopeptide repeat - - - 0.00000003576 65.0
HFD3_k127_1027416_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001814 271.0
HFD3_k127_1035308_0 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000645 234.0
HFD3_k127_1035308_1 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000000000000000000000000132 148.0
HFD3_k127_1035308_2 - - - - 0.0007951 50.0
HFD3_k127_1053836_0 Peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007826 431.0
HFD3_k127_1053836_1 mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 413.0
HFD3_k127_1053836_2 Low affinity iron permease - - - 0.00000000000000000000000000000000000000000005992 165.0
HFD3_k127_1053836_3 Dienelactone hydrolase family - - - 0.0000000000000000001603 88.0
HFD3_k127_106527_0 PFAM D-aminoacylase, C-terminal region K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 580.0
HFD3_k127_1080520_0 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000002384 187.0
HFD3_k127_1080520_1 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000009042 129.0
HFD3_k127_1080520_2 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.000000000000003052 79.0
HFD3_k127_1084909_0 - - - - 0.000000000000000000000000000000000000000001475 174.0
HFD3_k127_1084909_1 Prokaryotic N-terminal methylation motif - - - 0.00000002276 66.0
HFD3_k127_1084909_2 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00002538 57.0
HFD3_k127_1089346_0 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009094 406.0
HFD3_k127_1089346_1 - - - - 0.00004407 50.0
HFD3_k127_1094807_0 - - - - 0.00000000000000000000000000000000000000000000000000003478 199.0
HFD3_k127_1094807_1 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000006438 154.0
HFD3_k127_1094807_2 copper resistance K07245,K14166 - - 0.0000352 53.0
HFD3_k127_1096435_0 Lanthionine synthetase C family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006254 329.0
HFD3_k127_1096435_1 of the major facilitator superfamily K08151 - - 0.00000000000000000000000000000000000000000000000000000000000107 217.0
HFD3_k127_1096435_2 TIGRFAM geranylgeranyl reductase - - - 0.0000000000000000000000000000000000000000000000000000000895 211.0
HFD3_k127_1096435_3 Prolyl 4-hydroxylase alpha subunit homologues. - - - 0.000000000000000000000000000000000002832 140.0
HFD3_k127_1100576_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 422.0
HFD3_k127_1100576_1 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000000147 136.0
HFD3_k127_1100576_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000002647 134.0
HFD3_k127_1100576_3 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000002647 117.0
HFD3_k127_1101048_0 D-alanyl-d-alanine carboxypeptidase K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 402.0
HFD3_k127_1101048_1 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006548 351.0
HFD3_k127_1101048_2 - - - - 0.00000000000000000000005608 108.0
HFD3_k127_1104454_0 PFAM peptidase S45 penicillin amidase K01434,K07116 - 3.5.1.11,3.5.1.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005357 438.0
HFD3_k127_1104454_1 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001425 276.0
HFD3_k127_111071_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 575.0
HFD3_k127_111071_1 Phosphotriesterase K07048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 524.0
HFD3_k127_111071_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.0000000000000000000000000000000000001507 144.0
HFD3_k127_111271_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000397 568.0
HFD3_k127_111271_1 Carboxypeptidase regulatory-like domain - - - 0.00000005882 61.0
HFD3_k127_1116789_0 glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000002958 141.0
HFD3_k127_1116789_1 glycosyl transferase family 2 - - - 0.000000000000004109 83.0
HFD3_k127_112374_0 Two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 538.0
HFD3_k127_112374_1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000003668 179.0
HFD3_k127_112374_2 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000000006445 104.0
HFD3_k127_112374_3 PFAM membrane-flanked domain - - - 0.0000000000002771 78.0
HFD3_k127_112374_4 Domain of unknown function (DUF4912) K09942 - - 0.00008447 54.0
HFD3_k127_112684_0 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10562 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 437.0
HFD3_k127_112684_1 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate K18929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 437.0
HFD3_k127_112684_2 PFAM Uncharacterised ACR, YkgG family COG1556 K00782 - - 0.0000000000000000000003855 106.0
HFD3_k127_1128415_0 3-oxo-5-alpha-steroid 4-dehydrogenase K12343 - 1.3.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 288.0
HFD3_k127_1128415_1 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000009131 246.0
HFD3_k127_1132621_0 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 404.0
HFD3_k127_1132621_1 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000004696 161.0
HFD3_k127_1138486_0 Cys/Met metabolism PLP-dependent enzyme K01760,K17217 - 4.4.1.1,4.4.1.2,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 502.0
HFD3_k127_1138486_1 PFAM AMP-dependent synthetase and ligase - - - 0.000000000000006243 87.0
HFD3_k127_1142971_0 Alpha-L-arabinofuranosidase C-terminus K01209 - 3.2.1.55 1.868e-206 656.0
HFD3_k127_1142971_1 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000176 271.0
HFD3_k127_1142971_2 alpha-L-rhamnosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001318 245.0
HFD3_k127_1146065_0 PFAM Organic solvent tolerance protein K04744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009681 268.0
HFD3_k127_1146065_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000005728 97.0
HFD3_k127_1146736_0 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000004521 204.0
HFD3_k127_1146736_1 MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000001547 164.0
HFD3_k127_1146736_2 Putative mono-oxygenase ydhR - - - 0.0000000000000000002914 90.0
HFD3_k127_1153561_0 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008542 524.0
HFD3_k127_1153561_1 Mechanosensitive ion channel K05802,K22051 - - 0.0000000000000000000000000000000000000000000000000002544 198.0
HFD3_k127_1153561_2 - - - - 0.00000001136 61.0
HFD3_k127_1154449_0 Methyltransferase domain - - - 0.000000000000000000000000000001755 132.0
HFD3_k127_1167078_0 Nucleoside H+ symporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 397.0
HFD3_k127_1167078_2 Bacterial SH3 domain - - - 0.000000000000000000000000000000000000000000000000000000000000001624 230.0
HFD3_k127_1167078_3 cAMP biosynthetic process K12132 - 2.7.11.1 0.0000000000000000007471 98.0
HFD3_k127_1174728_0 transcriptional regulator K03556 - - 0.000000000000000000000000000000000000000000002053 181.0
HFD3_k127_1174728_1 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Binds and recognizes a DNA motif (called the malT box) 5'-GGA TG GA-3' K03556 GO:0003674,GO:0003700,GO:0005488,GO:0005515,GO:0005975,GO:0006355,GO:0008150,GO:0008152,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030246,GO:0031323,GO:0031326,GO:0042802,GO:0044238,GO:0048031,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070492,GO:0071704,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000001682 89.0
HFD3_k127_1179400_0 Domain of unknown function (DUF4136) - - - 0.000000000000000000000000000000000000001237 154.0
HFD3_k127_1179400_1 Domain of unknown function (DUF4136) - - - 0.00000000000000001115 89.0
HFD3_k127_1179400_2 - - - - 0.000000000001493 77.0
HFD3_k127_1180337_0 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000002318 183.0
HFD3_k127_1180337_1 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000007551 128.0
HFD3_k127_1180337_2 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000001321 111.0
HFD3_k127_1187960_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 2.62e-213 678.0
HFD3_k127_1187960_1 synthetase, class II (G H P K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 421.0
HFD3_k127_1187960_2 PFAM acyl-CoA dehydrogenase domain protein K00255,K11731 - 1.3.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 294.0
HFD3_k127_1187960_3 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009473 285.0
HFD3_k127_1187960_4 - - - - 0.0000000000000000000000000000000000000000000000000000004015 205.0
HFD3_k127_1187960_5 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000000872 193.0
HFD3_k127_1195117_0 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 366.0
HFD3_k127_1195117_1 - - - - 0.00000000000000000000000001678 114.0
HFD3_k127_1195377_0 Radical SAM superfamily K11779 - 2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 417.0
HFD3_k127_1195377_1 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000399 245.0
HFD3_k127_1195377_2 Fibronectin-binding A domain protein - - - 0.000000000000000000000000000000000000000000000306 185.0
HFD3_k127_1195454_0 Domain of unknown function (DUF3471) K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 526.0
HFD3_k127_1196528_0 Protein of unknown function (DUF2934) - - - 0.00000000000000000002022 97.0
HFD3_k127_1196528_1 Tfp pilus assembly protein FimV - - - 0.00000000000006813 79.0
HFD3_k127_1196528_2 GAF domain - - - 0.000000002251 59.0
HFD3_k127_1197722_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 314.0
HFD3_k127_1201731_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 6.095e-301 941.0
HFD3_k127_1201731_1 Lysin motif K08307 - - 0.00001351 53.0
HFD3_k127_1205411_0 CarboxypepD_reg-like domain K02014,K16089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 395.0
HFD3_k127_12083_0 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 362.0
HFD3_k127_12083_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000002572 276.0
HFD3_k127_12083_2 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000007645 129.0
HFD3_k127_1215506_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.01e-279 870.0
HFD3_k127_1219900_0 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 565.0
HFD3_k127_1219900_1 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000001611 210.0
HFD3_k127_1219900_2 Domain of unknown function (DUF4347) - - - 0.000000000000000000000000000000000000000000000000003101 209.0
HFD3_k127_1220716_0 oxidoreductase activity K12511 - - 0.000000000000000000000000000000000000000000000000001575 196.0
HFD3_k127_1220716_1 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000005595 186.0
HFD3_k127_1220716_2 von Willebrand factor, type A - - - 0.000000000000000000000000000000000003366 149.0
HFD3_k127_1220716_3 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000004456 112.0
HFD3_k127_1224036_0 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000007158 220.0
HFD3_k127_1243624_0 Glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 336.0
HFD3_k127_1243624_1 Transcriptional regulator, LysR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002819 264.0
HFD3_k127_1243624_3 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000001237 66.0
HFD3_k127_1247717_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 498.0
HFD3_k127_1247717_1 mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 397.0
HFD3_k127_1247717_2 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005419 389.0
HFD3_k127_1247717_3 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000002503 78.0
HFD3_k127_124944_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000001598 242.0
HFD3_k127_124944_1 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain K11527 - 2.7.13.3 0.00000000000000008257 95.0
HFD3_k127_124944_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K21025 - - 0.000003341 60.0
HFD3_k127_1251700_0 MotA TolQ ExbB proton channel K03561,K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003544 271.0
HFD3_k127_1251700_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000003687 224.0
HFD3_k127_1251700_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.00000000000000000000000000000000001428 138.0
HFD3_k127_1251700_3 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000000000000000000003571 111.0
HFD3_k127_1251700_4 TIGRFAM TonB K03832 - - 0.000000000000000001257 90.0
HFD3_k127_1251700_5 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.00000000000000006158 86.0
HFD3_k127_1251700_6 Tetratricopeptide repeat - - - 0.000000000000006414 85.0
HFD3_k127_1258224_0 valine-tRNA ligase activity K01873 GO:0000287,GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006417,GO:0006418,GO:0006438,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045903,GO:0046483,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0052689,GO:0060255,GO:0061475,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:2000112 6.1.1.9 6.944e-308 967.0
HFD3_k127_1258993_0 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001001 261.0
HFD3_k127_1258993_1 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000001557 239.0
HFD3_k127_1262630_0 alpha-L-rhamnosidase - - - 2.413e-227 721.0
HFD3_k127_126749_0 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000001542 166.0
HFD3_k127_126749_1 Transcriptional regulator K03641 - - 0.0000000000000000000000000000000000000001534 161.0
HFD3_k127_126749_2 Belongs to the 'phage' integrase family - - - 0.00000000000005213 74.0
HFD3_k127_1281193_0 PFAM binding-protein-dependent transport systems inner membrane component K02033,K15581 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001754 269.0
HFD3_k127_1281193_1 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000001256 195.0
HFD3_k127_1281193_2 Diguanylate cyclase K02034,K16201 - - 0.00000000000000000000000000000000000000000000000000002117 196.0
HFD3_k127_1281675_0 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 303.0
HFD3_k127_1281675_1 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000694 273.0
HFD3_k127_1288976_0 threonine synthase activity K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 328.0
HFD3_k127_1288976_1 Cysteine synthase B K12339 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002443 269.0
HFD3_k127_1288976_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000004512 254.0
HFD3_k127_1288976_3 Molybdopterin converting factor, small subunit K03636 - - 0.000000000000000000000000000165 117.0
HFD3_k127_1294016_0 siderophore transport K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000661 502.0
HFD3_k127_1294016_1 symporter activity K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009666 387.0
HFD3_k127_1300171_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 324.0
HFD3_k127_1300171_1 - - - - 0.00000000000000002589 87.0
HFD3_k127_1300171_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000006593 71.0
HFD3_k127_1301229_0 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 532.0
HFD3_k127_1301229_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 319.0
HFD3_k127_1301229_2 Beta-lactamase class C and other penicillin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005238 264.0
HFD3_k127_1301229_3 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000000005055 217.0
HFD3_k127_1301229_4 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000001351 186.0
HFD3_k127_1301506_0 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 343.0
HFD3_k127_1301506_1 Protein of unknown function (DUF433) - - - 0.000000000000000001259 85.0
HFD3_k127_1301506_2 - - - - 0.00000002369 57.0
HFD3_k127_1301959_0 Cysteine-rich domain K00113 - 1.1.5.3 1.339e-211 667.0
HFD3_k127_1301959_1 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000000000000000000000000000000001066 220.0
HFD3_k127_1301959_2 - K05594 - - 0.0000000000000000002057 94.0
HFD3_k127_1310200_0 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004847 391.0
HFD3_k127_1310200_1 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.0000000000000000000000000000000000000000000000000002513 193.0
HFD3_k127_1310200_2 - - - - 0.00000000000005069 78.0
HFD3_k127_1314755_0 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 389.0
HFD3_k127_1316063_0 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003277 633.0
HFD3_k127_1316063_1 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 622.0
HFD3_k127_1316063_2 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000611 217.0
HFD3_k127_1316063_3 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000007973 193.0
HFD3_k127_1318589_0 MacB-like periplasmic core domain K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006761 322.0
HFD3_k127_1318589_1 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000772 322.0
HFD3_k127_1318589_2 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009667 253.0
HFD3_k127_1318589_3 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000000000000000000006387 190.0
HFD3_k127_1318589_4 Belongs to the ClpA ClpB family K03696 - - 0.00000000000000000000000000000000000000000000003018 173.0
HFD3_k127_1318589_5 ChrR Cupin-like domain - - - 0.0000000000000000000001171 106.0
HFD3_k127_1320834_0 PFAM methyltransferase - - - 0.00000000000000000000000000000000001823 148.0
HFD3_k127_1320834_1 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000000000000000002447 115.0
HFD3_k127_1320834_2 RHS Repeat - - - 0.000000000000001994 90.0
HFD3_k127_1320834_3 Large extracellular alpha-helical protein - - - 0.00000000001999 76.0
HFD3_k127_1320834_4 PKD domain containing protein - - - 0.00000001161 68.0
HFD3_k127_1320834_5 Belongs to the peptidase M10A family K07994 GO:0000003,GO:0000323,GO:0001501,GO:0001503,GO:0001554,GO:0001649,GO:0001666,GO:0001958,GO:0001968,GO:0002791,GO:0002793,GO:0003006,GO:0003416,GO:0003417,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0004252,GO:0005102,GO:0005488,GO:0005509,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005773,GO:0005794,GO:0005911,GO:0006508,GO:0006518,GO:0006807,GO:0006950,GO:0007275,GO:0007507,GO:0007548,GO:0007567,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008237,GO:0008270,GO:0008406,GO:0008585,GO:0009056,GO:0009605,GO:0009612,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009887,GO:0009888,GO:0009987,GO:0010033,GO:0012505,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022411,GO:0022414,GO:0022602,GO:0022617,GO:0030054,GO:0030154,GO:0030198,GO:0030282,GO:0030326,GO:0030574,GO:0031214,GO:0032501,GO:0032502,GO:0032504,GO:0032879,GO:0032880,GO:0032963,GO:0033554,GO:0034405,GO:0034641,GO:0035107,GO:0035108,GO:0035113,GO:0035116,GO:0035137,GO:0035265,GO:0036075,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0042698,GO:0043062,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0043627,GO:0044057,GO:0044058,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044267,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0044706,GO:0044849,GO:0044877,GO:0045137,GO:0046545,GO:0046581,GO:0046660,GO:0046872,GO:0046914,GO:0048306,GO:0048511,GO:0048513,GO:0048518,GO:0048522,GO:0048589,GO:0048598,GO:0048608,GO:0048609,GO:0048705,GO:0048731,GO:0048736,GO:0048856,GO:0048869,GO:0050708,GO:0050714,GO:0050750,GO:0050789,GO:0050794,GO:0050878,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051216,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051704,GO:0051716,GO:0060173,GO:0060348,GO:0060349,GO:0060350,GO:0060351,GO:0060456,GO:0061448,GO:0061458,GO:0065007,GO:0065008,GO:0070011,GO:0070201,GO:0070325,GO:0070482,GO:0071498,GO:0071704,GO:0071840,GO:0072359,GO:0090087,GO:0090186,GO:0090187,GO:0098868,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1903530,GO:1903532,GO:1904242,GO:1904244,GO:1904951 - 0.000002262 61.0
HFD3_k127_1332112_0 Low molecular weight phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001036 295.0
HFD3_k127_1332112_1 acyl-CoA dehydrogenase activity - - - 0.000000000000000000000000000000000000000000005891 166.0
HFD3_k127_1332112_2 2OG-Fe(II) oxygenase superfamily - - - 0.00000000000000000000000000000000000000001052 162.0
HFD3_k127_1339703_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007549 602.0
HFD3_k127_1339703_1 peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 366.0
HFD3_k127_1339703_2 Putative lumazine-binding - - - 0.000000000000000000000000000000000000000004037 159.0
HFD3_k127_1339780_0 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004925 361.0
HFD3_k127_1339780_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00016 - 1.1.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 331.0
HFD3_k127_1339780_2 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.00000000000000000000000000000000002581 137.0
HFD3_k127_1340204_0 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 578.0
HFD3_k127_1340204_1 Domain of unknown function (DUF4349) - - - 0.00000000000000000000000000000000002519 146.0
HFD3_k127_1343722_0 Peptidase family M23 K21472 - - 0.00000000000000000000000000000000000000000000000000001493 196.0
HFD3_k127_1345758_0 SPFH domain-Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006466 286.0
HFD3_k127_1345758_1 Putative adhesin K11621 - - 0.0008302 46.0
HFD3_k127_1355358_0 Phage late control gene D protein (GPD) K11904 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006056 479.0
HFD3_k127_1355358_1 Domain of unknown function (DUF4123) - - - 0.000000000000000000000000000000000000000000001594 170.0
HFD3_k127_1355358_2 PAAR repeat-containing protein - - - 0.0000000000000000000000000000000000000000002258 159.0
HFD3_k127_1356950_0 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000002598 237.0
HFD3_k127_1356950_1 Universal stress protein family - - - 0.0000000000000000000000000001053 126.0
HFD3_k127_1364470_0 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005808 439.0
HFD3_k127_1364470_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714,K21062 - 3.5.4.22,4.3.3.7 0.0000000000000000004065 87.0
HFD3_k127_1370779_0 Methyltransferase small domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 476.0
HFD3_k127_1370779_1 PFAM inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000444 151.0
HFD3_k127_1370779_2 peroxiredoxin activity K03564 - 1.11.1.15 0.000000000000000000000000000002678 122.0
HFD3_k127_1370779_3 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000008596 119.0
HFD3_k127_1370779_4 Redoxin K03564 - 1.11.1.15 0.00000000000003154 72.0
HFD3_k127_1370779_5 - - - - 0.000001259 60.0
HFD3_k127_13776_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000002828 262.0
HFD3_k127_13776_1 Tyrosine phosphatase family - - - 0.0000000000000000000009598 102.0
HFD3_k127_13776_2 - - - - 0.00000000993 61.0
HFD3_k127_1382740_0 Zn_pept - - - 0.00000000000000000000000002574 113.0
HFD3_k127_1382740_1 Tetratricopeptide repeat - - - 0.0000000000000000000001574 100.0
HFD3_k127_1382740_2 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.0000000000000001258 84.0
HFD3_k127_1384184_0 - - - - 0.00000000000000000009625 97.0
HFD3_k127_1389739_0 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177,K03483 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000008186 215.0
HFD3_k127_1389739_1 Phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000000000000001935 177.0
HFD3_k127_139092_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000004447 113.0
HFD3_k127_1391633_0 Domain of unknown function (DUF3488) - - - 0.00000000000000000000000000000000000000000000000000000000000001157 237.0
HFD3_k127_1397490_0 Serine carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 457.0
HFD3_k127_1397490_1 Peptidase family M1 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009432 329.0
HFD3_k127_1397490_2 chlorophyll binding K01186,K02487,K12543 - 3.2.1.18 0.000000000000000001062 94.0
HFD3_k127_1397490_3 - - - - 0.00000002117 61.0
HFD3_k127_139757_0 helix_turn_helix, arabinose operon control protein K07506 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001217 261.0
HFD3_k127_139757_1 Protein of unknown function (DUF1223) - - - 0.0000000000000000000000000000000000000000000000000000000004355 219.0
HFD3_k127_139757_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000003732 224.0
HFD3_k127_139757_3 Cytochrome P460 - - - 0.000000000000000000000000000000000000000007061 159.0
HFD3_k127_139757_4 Cysteine-rich secretory protein family - - - 0.000000000000000000000000002442 119.0
HFD3_k127_139757_5 - - - - 0.00000000000000000001771 105.0
HFD3_k127_139757_6 general secretion pathway protein G K02456 - - 0.00002729 53.0
HFD3_k127_1401693_0 Glycosyl hydrolase family 1 - - - 5.177e-222 692.0
HFD3_k127_1401693_1 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 304.0
HFD3_k127_1401693_2 UDP-glucose 4-epimerase K01784 - 5.1.3.2 0.000000000000002162 77.0
HFD3_k127_1408498_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.0000000000000000000000000000000000000000000000000000009749 194.0
HFD3_k127_1408498_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000002477 164.0
HFD3_k127_1409030_0 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 384.0
HFD3_k127_1409030_1 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 289.0
HFD3_k127_1409030_2 Belongs to the metal hydrolase YfiT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001633 248.0
HFD3_k127_1409030_4 Belongs to the bacterial plant glucose-1-phosphate adenylyltransferase family K00975 - 2.7.7.27 0.0000000000000000001778 88.0
HFD3_k127_1409030_5 exo-alpha-(2->6)-sialidase activity - - - 0.00003411 56.0
HFD3_k127_1411925_0 lactate racemase activity K22373 - 5.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008728 545.0
HFD3_k127_1411925_1 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 291.0
HFD3_k127_1411925_2 lipoprotein localization to outer membrane K02004,K09808 - - 0.000000000000000000000000000000000000000000000007566 185.0
HFD3_k127_1411925_3 - - - - 0.00000000000000001204 89.0
HFD3_k127_1412772_0 WD40-like Beta Propeller Repeat - - - 1.051e-234 736.0
HFD3_k127_1412772_1 cAMP biosynthetic process - - - 0.0000000000000001049 82.0
HFD3_k127_1413958_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007769 574.0
HFD3_k127_1413958_1 - - - - 0.00000001419 66.0
HFD3_k127_1420010_0 Phage tail sheath C-terminal domain K06907 - - 1.577e-241 764.0
HFD3_k127_1420010_1 T4-like virus tail tube protein gp19 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004826 274.0
HFD3_k127_1420010_2 Protein of unknown function (DUF4255) - - - 0.00000000000000000000000000000000000000009872 155.0
HFD3_k127_1420010_3 - - - - 0.00000000000000000000000000000000000009678 153.0
HFD3_k127_1420010_4 Phage tail sheath protein subtilisin-like domain - - - 0.0000000000000000000001496 98.0
HFD3_k127_14273_0 Vault protein inter-alpha-trypsin domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005217 346.0
HFD3_k127_14273_1 - - - - 0.0000000002075 70.0
HFD3_k127_1434943_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003842 499.0
HFD3_k127_1434943_1 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00966,K16881 - 2.7.7.13,5.4.2.8 0.0000000000000000000000000000000001042 136.0
HFD3_k127_1435395_0 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 482.0
HFD3_k127_1435395_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 371.0
HFD3_k127_1438347_0 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000004103 126.0
HFD3_k127_1439920_0 COG0515 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000003574 124.0
HFD3_k127_1440835_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003061 270.0
HFD3_k127_1443674_0 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749 297.0
HFD3_k127_1443674_1 6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000006442 259.0
HFD3_k127_1443674_2 DJ-1/PfpI family - - - 0.000000000000000000000000000000000000000000000000000000000000000001846 235.0
HFD3_k127_1443674_3 protein phosphatase 2C domain protein K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000001388 216.0
HFD3_k127_1443674_4 Sucrose-6F-phosphate phosphohydrolase - - - 0.00000000000000000000000000000000000000000000000001187 189.0
HFD3_k127_1443674_5 Small Multidrug Resistance protein K03297,K11741 - - 0.00000000000000000000000000000000000000004639 154.0
HFD3_k127_1443674_6 Forkhead associated domain - - - 0.0000000000000003801 91.0
HFD3_k127_1443674_7 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00001369 49.0
HFD3_k127_1443674_8 Psort location Cytoplasmic, score - - - 0.00005925 55.0
HFD3_k127_1450257_0 gluconolactonase K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 402.0
HFD3_k127_1450257_1 phosphatidate phosphatase activity - - - 0.00000000000000006341 92.0
HFD3_k127_1450257_2 helix_turn_helix, Lux Regulon - - - 0.00000000004068 72.0
HFD3_k127_1454138_0 COGs COG0160 4-aminobutyrate aminotransferase and related aminotransferase K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 535.0
HFD3_k127_1454138_1 Amidohydrolase family K01464 - 3.5.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 298.0
HFD3_k127_1458433_0 Oxidoreductase family, C-terminal alpha beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 346.0
HFD3_k127_1458433_1 and related - - - 0.00000000000000000000000000000000000000000000000000000000000000362 235.0
HFD3_k127_1458433_2 DoxX K16937 - 1.8.5.2 0.00000000000000000000000000000214 128.0
HFD3_k127_1458433_3 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000673 124.0
HFD3_k127_1460691_0 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002293 275.0
HFD3_k127_1460691_1 dienelactone hydrolase - - - 0.00000000000000000000000000000000389 137.0
HFD3_k127_1467814_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 413.0
HFD3_k127_1467814_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 317.0
HFD3_k127_1467814_10 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000007146 49.0
HFD3_k127_1467814_2 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001557 269.0
HFD3_k127_1467814_3 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000004336 213.0
HFD3_k127_1467814_4 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000000001267 199.0
HFD3_k127_1467814_5 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000005076 139.0
HFD3_k127_1467814_6 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000002059 123.0
HFD3_k127_1467814_7 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000001375 106.0
HFD3_k127_1467814_8 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000001305 101.0
HFD3_k127_1467814_9 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000001304 59.0
HFD3_k127_147358_0 GAF domain K02584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000302 293.0
HFD3_k127_1475823_0 domain protein - - - 2.054e-239 782.0
HFD3_k127_1475823_1 domain protein - - - 4.478e-229 753.0
HFD3_k127_1479289_0 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000000000000000002988 90.0
HFD3_k127_1479289_1 TPR repeat - - - 0.00001097 57.0
HFD3_k127_1479289_2 Transglutaminase-like superfamily - - - 0.00001489 57.0
HFD3_k127_1484813_0 PFAM Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000007791 237.0
HFD3_k127_1484813_1 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000006855 200.0
HFD3_k127_1484813_2 peptidyl-lysine modification to peptidyl-hypusine - - - 0.0000000000000000000000000000000000000000001151 163.0
HFD3_k127_1484813_3 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000001355 136.0
HFD3_k127_1493913_0 Aerotolerance regulator N-terminal - - - 0.0000000000000000000000000000000000000000000000000001024 208.0
HFD3_k127_1501168_0 Belongs to the glycosyl hydrolase 31 family K01811 - 3.2.1.177 1.621e-257 807.0
HFD3_k127_1505186_0 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 464.0
HFD3_k127_1505186_1 PFAM phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 379.0
HFD3_k127_1505186_2 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000006488 168.0
HFD3_k127_1506686_0 Flotillin K07192 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 387.0
HFD3_k127_1513746_0 GTP-binding GTPase Middle Region K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009988 402.0
HFD3_k127_1513746_1 tRNA processing K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 295.0
HFD3_k127_1513746_2 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002464 273.0
HFD3_k127_1513746_3 PFAM LemA family protein K03744 - - 0.0000000000000000000000000000000000000000000000000000000004243 207.0
HFD3_k127_1513746_4 Involved in DNA repair and RecF pathway recombination K03474,K03584 GO:0008150,GO:0009314,GO:0009628,GO:0050896 2.6.99.2 0.000000000000000000000000000000000000000007051 164.0
HFD3_k127_1513746_5 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000000000000000000000000000000000009587 157.0
HFD3_k127_1513746_6 Tyrosine phosphatase family - - - 0.00000000000000000005277 97.0
HFD3_k127_1513746_7 - - - - 0.000000000025 74.0
HFD3_k127_1514252_0 FAD binding domain K11472 - - 0.0000000000000000000000000000000000000000000000000000000004536 218.0
HFD3_k127_1514252_1 Domain of unknown function (DUF309) K09763 - - 0.000000000004491 70.0
HFD3_k127_1517013_0 Putative stress-induced transcription regulator - - - 0.000000000001977 67.0
HFD3_k127_1517013_1 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0005376 53.0
HFD3_k127_1518985_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000363 247.0
HFD3_k127_1520608_0 Proline racemase K01777 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016855,GO:0018112,GO:0019752,GO:0036361,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0047661,GO:0050346,GO:0071704,GO:1901564 5.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 546.0
HFD3_k127_1520608_1 4Fe-4S binding domain K00395,K02572,K03616 - 1.8.99.2 0.0000000000000000000000000000000000000000002977 160.0
HFD3_k127_1522114_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 302.0
HFD3_k127_1522114_1 Thioesterase superfamily K07107 - - 0.00000000000000000001939 97.0
HFD3_k127_1530377_0 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 341.0
HFD3_k127_1530377_1 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000003923 169.0
HFD3_k127_1530377_2 Protein involved in hydrolase activity K06889 - - 0.000000000000000000000000000000000008847 151.0
HFD3_k127_1530377_3 - - - - 0.000000009597 63.0
HFD3_k127_1532538_0 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006051 410.0
HFD3_k127_1532538_1 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000003992 192.0
HFD3_k127_1532538_2 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.00000000002128 65.0
HFD3_k127_1544418_0 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000000000000003836 153.0
HFD3_k127_1544418_1 Belongs to the GSP D family K02453 - - 0.0000000000000000000000000000000009304 150.0
HFD3_k127_1544418_2 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000001661 106.0
HFD3_k127_1545244_0 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007937 338.0
HFD3_k127_1545244_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007892 323.0
HFD3_k127_1545244_2 Protein of unknown function (DUF1326) - - - 0.000000000000000000000000000000000000000000000000000000000000000008365 228.0
HFD3_k127_1549197_0 Aminotransferase class-V K00830,K00839 GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.112,2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 398.0
HFD3_k127_1549197_1 Forkhead associated domain - - - 0.000000000000000000000000000000000000009216 160.0
HFD3_k127_1549197_2 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.000000000000000000000000000001873 124.0
HFD3_k127_1558239_0 L-sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005111 432.0
HFD3_k127_1558239_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000002736 209.0
HFD3_k127_1558264_0 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 539.0
HFD3_k127_1558264_1 Cytochrome c K08685 - 1.4.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000004925 257.0
HFD3_k127_1558264_2 - - - - 0.00000001373 58.0
HFD3_k127_1558671_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 554.0
HFD3_k127_1558671_1 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000002837 157.0
HFD3_k127_1558671_2 metallopeptidase activity - - - 0.0000000000000000000000000000000000005812 154.0
HFD3_k127_1558671_3 Major facilitator Superfamily - - - 0.000212 51.0
HFD3_k127_1560156_0 metalloendopeptidase activity K01283 - 3.4.15.1 8.062e-247 777.0
HFD3_k127_1560156_1 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 414.0
HFD3_k127_1560156_2 Transglycosylase associated protein - - - 0.000000000000000000000005133 104.0
HFD3_k127_1560156_3 WD40 domain protein beta Propeller - - - 0.00000000000000001466 88.0
HFD3_k127_1562879_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 293.0
HFD3_k127_1562879_1 deoxyhypusine monooxygenase activity K05385 - - 0.0000000000000000000000000000000000000000000000001526 181.0
HFD3_k127_1563591_0 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007779 313.0
HFD3_k127_1563591_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000001399 227.0
HFD3_k127_1563591_2 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000001014 166.0
HFD3_k127_156644_0 MMPL family K07003 - - 0.000000000000000003994 92.0
HFD3_k127_156644_1 Outer membrane lipoprotein-sorting protein - - - 0.00001187 56.0
HFD3_k127_157244_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007555 291.0
HFD3_k127_157244_1 ROK family - - - 0.00000000000000000000000000000000000000000000000000000000003097 221.0
HFD3_k127_157244_2 glyoxalase III activity - - - 0.000000000008325 70.0
HFD3_k127_157244_3 ASPIC and UnbV - - - 0.0001209 45.0
HFD3_k127_1575528_0 Sigma-54 interaction domain - - - 0.0000000007431 61.0
HFD3_k127_1575528_1 PAS domain - - - 0.00000001896 67.0
HFD3_k127_158964_0 amine oxidase K00276 - 1.4.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 397.0
HFD3_k127_158964_1 PFAM peptidase M48 Ste24p - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 319.0
HFD3_k127_1592155_0 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000004473 239.0
HFD3_k127_1592155_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000002357 190.0
HFD3_k127_1594797_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 3.885e-219 693.0
HFD3_k127_1594797_1 ROK family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008087 267.0
HFD3_k127_1594797_2 - - - - 0.000000000000000000000000000000000008433 145.0
HFD3_k127_1597206_0 heat shock protein DnaJ domain protein K05516 - - 0.000000000000000000000000000000000000006366 150.0
HFD3_k127_1597206_1 Domain of unknown function (DUF5122) beta-propeller - - - 0.00000000000000000000000005695 116.0
HFD3_k127_1599046_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000005737 251.0
HFD3_k127_159918_0 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - 0.000000000000000000001174 100.0
HFD3_k127_159918_1 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.00000000000000004331 86.0
HFD3_k127_1599407_0 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 529.0
HFD3_k127_1601265_0 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 480.0
HFD3_k127_1601265_1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006224 315.0
HFD3_k127_1601265_2 Phosphoribulokinase / Uridine kinase family K00855,K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.19,2.7.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000001387 257.0
HFD3_k127_1601265_3 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.000000000000000000000000000000000000000000001219 168.0
HFD3_k127_1601966_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008519 571.0
HFD3_k127_1601966_1 OsmC-like protein - - - 0.000000000000000000000000000000000000003536 151.0
HFD3_k127_1602030_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K00256 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005599 543.0
HFD3_k127_1602030_1 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000000000000000000533 209.0
HFD3_k127_1602030_2 protein conserved in bacteria - - - 0.00000000000000000000000000000000002363 138.0
HFD3_k127_1602550_0 Domain of unknown function (DUF4440) - - - 0.0000000000000000000000000000000000000004241 154.0
HFD3_k127_1602550_1 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000004311 144.0
HFD3_k127_1602550_2 Stress responsive A/B Barrel Domain - - - 0.0000000000000000114 85.0
HFD3_k127_160728_0 Caspase domain - - - 0.0004919 53.0
HFD3_k127_1611934_0 Dehydrogenase E1 component K11381 - 1.2.4.4 6.423e-220 696.0
HFD3_k127_1611934_1 Phage integrase family - - - 0.000001178 56.0
HFD3_k127_1611934_2 - - - - 0.0009014 46.0
HFD3_k127_1612387_0 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004083 278.0
HFD3_k127_1612387_1 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000003488 230.0
HFD3_k127_1612387_2 oxidation-reduction process K09022 - 3.5.99.10 0.0000000000000000000000000000000000001548 142.0
HFD3_k127_1612387_3 - - - - 0.000000000004064 72.0
HFD3_k127_1615541_0 Peptidase C14 caspase catalytic subunit p20 - - - 0.000000000000000000000000000000005166 135.0
HFD3_k127_1615541_1 TPR domain protein - - - 0.00002129 53.0
HFD3_k127_1616329_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 1.037e-204 647.0
HFD3_k127_1616329_1 Peptidase M56 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 462.0
HFD3_k127_162192_0 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 368.0
HFD3_k127_162192_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000001044 222.0
HFD3_k127_162192_2 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000002291 198.0
HFD3_k127_162192_3 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000007011 143.0
HFD3_k127_1622074_0 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001222 289.0
HFD3_k127_1622074_1 Ferritin, Dps family protein K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000009571 215.0
HFD3_k127_1622074_2 - - - - 0.000000000001315 69.0
HFD3_k127_1627396_0 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 286.0
HFD3_k127_1627396_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003335 296.0
HFD3_k127_1627396_2 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000004127 272.0
HFD3_k127_1629651_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 434.0
HFD3_k127_1629651_1 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 314.0
HFD3_k127_1629651_2 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000005044 163.0
HFD3_k127_1629651_3 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000001139 150.0
HFD3_k127_162976_0 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000421 252.0
HFD3_k127_1631906_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000129 233.0
HFD3_k127_1633351_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000006005 123.0
HFD3_k127_1633351_1 Hep Hag repeat protein - - - 0.0000003468 55.0
HFD3_k127_163658_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 4.825e-285 900.0
HFD3_k127_163658_1 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000361 93.0
HFD3_k127_1653374_0 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000009792 164.0
HFD3_k127_1653374_1 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000001479 141.0
HFD3_k127_1653374_2 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.000009605 52.0
HFD3_k127_1660722_0 - - - - 0.0000000000000000000000000000000000000000000000000000001103 201.0
HFD3_k127_1660722_1 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) K08964 - 4.2.1.109 0.00000000000000000000000000000000000007929 149.0
HFD3_k127_1660722_2 Protein of unknown function (DUF2847) - - - 0.00000000000000000000000006847 111.0
HFD3_k127_1660722_3 PFAM glycosyl transferase family 39 - - - 0.000000000000000000002272 109.0
HFD3_k127_1662738_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 378.0
HFD3_k127_1662738_1 - - - - 0.0000000000000000000001763 107.0
HFD3_k127_1662777_0 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.000000000000000000000000000000000000005274 157.0
HFD3_k127_1664399_0 glutamate decarboxylase activity K01593 - 4.1.1.105,4.1.1.28 0.00000000000000000000000000000000000000000000000005001 182.0
HFD3_k127_1664424_0 Peptidase dimerisation domain protein K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000001615 228.0
HFD3_k127_1664424_1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.0000000000000000000004269 101.0
HFD3_k127_1664424_2 Redoxin domain protein - - - 0.000001035 58.0
HFD3_k127_1664980_0 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 314.0
HFD3_k127_1664980_1 Cupin 2, conserved barrel domain protein K11477 - - 0.000000000000000000000000000000000000000000000000002339 187.0
HFD3_k127_1664980_2 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000641 171.0
HFD3_k127_1664980_3 Belongs to the glycosyl hydrolase 13 family - - - 0.00000000000000006197 85.0
HFD3_k127_166913_0 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000001143 199.0
HFD3_k127_166913_1 PFAM Nickel cobalt transporter, high-affinity - - - 0.000000000000000000000000000000000000000000000000005523 190.0
HFD3_k127_166913_2 bacterial (prokaryotic) histone like domain K03530 - - 0.00000000000000000000000000000000005821 137.0
HFD3_k127_166913_3 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000005402 132.0
HFD3_k127_166913_4 Prokaryotic N-terminal methylation motif K02650 - - 0.00000113 52.0
HFD3_k127_1672682_0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 421.0
HFD3_k127_1672682_1 PDZ domain (Also known as DHR or GLGF) K08372 - - 0.00000000000000000000000000000000000000000000000000000000000000000001303 241.0
HFD3_k127_1672682_2 Lamin Tail Domain - - - 0.0000000000000000000000000000000004913 153.0
HFD3_k127_1672682_3 guanyl-nucleotide exchange factor activity K06978,K12287,K21105 - 3.1.1.102 0.0000000000000000000000000000001252 145.0
HFD3_k127_1672682_4 Putative adhesin - - - 0.00000000000000000005451 99.0
HFD3_k127_1673708_0 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008917 414.0
HFD3_k127_1673708_1 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000000003411 216.0
HFD3_k127_1673708_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.000000000000000000007122 94.0
HFD3_k127_1678544_0 helix_turn_helix isocitrate lyase regulation K13641 - - 0.000000000000000005895 87.0
HFD3_k127_1678544_1 transglycosylase K08309 - - 0.00000000000000006616 87.0
HFD3_k127_1678544_2 Belongs to the 5'-nucleotidase family K11751 - 3.1.3.5,3.6.1.45 0.00000003281 65.0
HFD3_k127_1690438_0 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006188 511.0
HFD3_k127_1690438_1 Major Facilitator Superfamily K02575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 417.0
HFD3_k127_1690438_2 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009878 316.0
HFD3_k127_1690438_3 Cytochrome c - - - 0.000000000000000000000000000000000000000000001498 170.0
HFD3_k127_1690438_4 cytochrome c - - - 0.0000000000000000000000000000000000000002116 156.0
HFD3_k127_1701707_0 Hep Hag repeat protein K21449 - - 0.000000000000000000000000000000000000000000000000000000000000007275 222.0
HFD3_k127_1701707_1 domain, Protein - - - 0.0000000000000000000000000000006841 140.0
HFD3_k127_1701707_3 Type VI secretion system effector, Hcp K11903 - - 0.0000000005616 67.0
HFD3_k127_1706414_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000173 232.0
HFD3_k127_1706414_1 Divergent 4Fe-4S mono-cluster - - - 0.0000000000000000000000000000000000000000000000003313 181.0
HFD3_k127_1706414_2 Vault protein inter-alpha-trypsin domain K07114 - - 0.000000000000000000000000000000000000000000000003533 183.0
HFD3_k127_1710304_0 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003739 248.0
HFD3_k127_1710304_1 PFAM Haloacid dehalogenase domain protein hydrolase - - - 0.000000000000000000000000000000002903 139.0
HFD3_k127_1710304_2 PFAM transposase, IS4 family protein - - - 0.0000001493 54.0
HFD3_k127_1711608_0 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000000001538 216.0
HFD3_k127_1711608_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000001393 126.0
HFD3_k127_171293_0 ABC transporter K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005518 261.0
HFD3_k127_171293_1 ABC transporter K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002705 250.0
HFD3_k127_171293_2 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000007202 98.0
HFD3_k127_171293_3 SurA N-terminal domain K07533 - 5.2.1.8 0.00000000000000000003964 104.0
HFD3_k127_1715713_0 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 466.0
HFD3_k127_1715713_1 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007573 378.0
HFD3_k127_1715713_2 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 344.0
HFD3_k127_1715713_3 Transcriptional regulatory protein, C terminal K07665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 319.0
HFD3_k127_1715713_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000007943 126.0
HFD3_k127_1715713_5 monooxygenase activity - - - 0.00000000000000000000000000001919 121.0
HFD3_k127_1715713_7 Histidine kinase - - - 0.0006407 49.0
HFD3_k127_1722613_0 KaiC K08482 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 557.0
HFD3_k127_1722613_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 415.0
HFD3_k127_1722613_2 - - - - 0.000000000000000000000000000009562 124.0
HFD3_k127_1723536_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006391 279.0
HFD3_k127_1729385_0 Domain of unknown function (DUF389) - - - 0.000000000000000000000000000000000000000004309 170.0
HFD3_k127_1729770_0 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009128 358.0
HFD3_k127_1729770_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007322 299.0
HFD3_k127_1729770_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000001764 162.0
HFD3_k127_1729770_3 - - - - 0.000000000000001637 85.0
HFD3_k127_1730604_0 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 419.0
HFD3_k127_1733610_0 MacB-like periplasmic core domain - - - 8.168e-206 667.0
HFD3_k127_1733610_1 Penicillinase repressor - - - 0.000000000000000000000000000000000000000000000001407 177.0
HFD3_k127_1733610_2 - - - - 0.000000000000000000000000000000000000000000000002264 198.0
HFD3_k127_1733610_3 Peptidase M56 - - - 0.00000000000000000000000000003389 125.0
HFD3_k127_1733610_4 - - - - 0.00000000000000009553 91.0
HFD3_k127_1734924_0 PFAM Peptidase M19, renal dipeptidase K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009607 339.0
HFD3_k127_1734924_1 Periplasmic protease - - - 0.0000000001425 65.0
HFD3_k127_1735128_0 Alcohol dehydrogenase GroES-like domain K00001,K18369 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 569.0
HFD3_k127_1735128_1 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000002131 205.0
HFD3_k127_1735128_2 COG0720 6-pyruvoyl-tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000003988 61.0
HFD3_k127_1735128_3 transposase activity - - - 0.0000009189 52.0
HFD3_k127_1739243_0 nucleotide metabolic process - - - 0.0000000000000000000000000000000000000000000000000000001924 203.0
HFD3_k127_1739243_1 von Willebrand factor, type A - - - 0.00000000000000000000000001533 113.0
HFD3_k127_1745554_0 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 340.0
HFD3_k127_1745554_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000001297 151.0
HFD3_k127_1748285_0 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.00000000000000000000000000000000000000000000000006052 185.0
HFD3_k127_1748285_1 Sodium/calcium exchanger protein K07300 - - 0.00000000000000000000000000000000000000000005154 163.0
HFD3_k127_1748432_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 533.0
HFD3_k127_1748432_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000002445 195.0
HFD3_k127_1758008_0 Carboxypeptidase regulatory-like domain - - - 0.0 1047.0
HFD3_k127_1758008_1 PFAM Na dependent nucleoside transporter K03317 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 332.0
HFD3_k127_1758008_2 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000001541 267.0
HFD3_k127_1758008_3 MbtH-like protein K05375 - - 0.0000000000000000000000000000000157 129.0
HFD3_k127_1758008_4 Transposase IS200 like - - - 0.000000000000000000008628 98.0
HFD3_k127_1758008_5 Belongs to the carbohydrate kinase PfkB family K21057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0071704 2.7.1.213 0.000000005884 68.0
HFD3_k127_1758008_6 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0000002356 53.0
HFD3_k127_176681_0 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004871 592.0
HFD3_k127_176681_1 Protein of unknown function (DUF1003) - - - 0.000000000000000000000000000000000000000000085 166.0
HFD3_k127_176965_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 452.0
HFD3_k127_176965_1 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000009493 107.0
HFD3_k127_1770381_0 Belongs to the ClpA ClpB family K03696 - - 0.0000000000000000000000000000000000000000001431 166.0
HFD3_k127_1770381_1 - - - - 0.000002223 59.0
HFD3_k127_1770749_0 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 460.0
HFD3_k127_1770749_1 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 338.0
HFD3_k127_1770749_2 Molybdopterin oxidoreductase Fe4S4 domain K08357 - - 0.00000000000000000000000000000000000000000000000000000002168 214.0
HFD3_k127_1770749_3 Protein of unknown function (DUF3341) - - - 0.0005076 46.0
HFD3_k127_17753_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840,K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 531.0
HFD3_k127_17753_1 TIGRFAM Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000001044 102.0
HFD3_k127_1776750_0 Glycosyltransferase family 87 - - - 0.00000000000003301 85.0
HFD3_k127_1776750_1 - - - - 0.0000000000006072 79.0
HFD3_k127_1776750_3 O-Antigen ligase K18814 - - 0.0000000004197 72.0
HFD3_k127_1778238_0 efflux transmembrane transporter activity - - - 1.334e-200 653.0
HFD3_k127_1778238_1 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 459.0
HFD3_k127_1778238_2 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003209 271.0
HFD3_k127_1781886_0 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008243 282.0
HFD3_k127_1781886_1 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000002386 168.0
HFD3_k127_1781886_2 Trehalose utilisation K09992 - - 0.000000000000000009947 88.0
HFD3_k127_1781886_3 - - - - 0.00000000005688 68.0
HFD3_k127_178344_0 esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 321.0
HFD3_k127_178344_1 Alpha/beta hydrolase of unknown function (DUF900) - - - 0.0000000000000008016 81.0
HFD3_k127_1790396_0 PFAM molybdopterin dehydrogenase, FAD-binding K11178 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 365.0
HFD3_k127_1790396_1 aldehyde oxidase and xanthine dehydrogenase a b hammerhead K11177 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000004337 224.0
HFD3_k127_1794621_0 Hydrolase CocE NonD family - - - 1e-322 998.0
HFD3_k127_1794621_1 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000002665 151.0
HFD3_k127_1794621_2 serine threonine protein kinase afsK - - - 0.000000000000000000000000000000000000008612 147.0
HFD3_k127_180288_0 Alpha-L-arabinofuranosidase C-terminus K01209 - 3.2.1.55 2.253e-246 770.0
HFD3_k127_180288_1 PA14 domain K05349 - 3.2.1.21 4.993e-203 638.0
HFD3_k127_180288_2 Belongs to the 'phage' integrase family K03733,K04763 - - 0.0004395 45.0
HFD3_k127_1803494_0 Y_Y_Y domain - - - 0.00000000000000000000000000000000000000000000000000000000004057 223.0
HFD3_k127_1803494_1 Transcriptional regulator K06921 - - 0.0000000000000000000000000000000000000000000000000000000001371 214.0
HFD3_k127_1804571_0 transmembrane transporter activity K03535,K08194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 439.0
HFD3_k127_1804571_1 Alpha/beta hydrolase family K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 408.0
HFD3_k127_1804571_2 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005756 269.0
HFD3_k127_1804862_0 Belongs to the glycosyl hydrolase 30 family K01201 - 3.2.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 601.0
HFD3_k127_1804862_1 esterase - - - 0.00000002429 57.0
HFD3_k127_1814173_0 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000001229 171.0
HFD3_k127_1814173_1 PhoQ Sensor K07640 - 2.7.13.3 0.0000000000000000000000000000000002686 135.0
HFD3_k127_1817244_0 chlorophyll binding - - - 0.00000000000000000000000000000000000000000000000000000003142 212.0
HFD3_k127_1817244_1 von Willebrand factor, type A - - - 0.00000000000000000000000000000001251 139.0
HFD3_k127_1817244_2 ASPIC and UnbV - - - 0.00000000000000000000001136 104.0
HFD3_k127_1819308_0 TonB-dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000006406 220.0
HFD3_k127_1828996_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 364.0
HFD3_k127_1828996_1 AcrB/AcrD/AcrF family K03296 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004218 271.0
HFD3_k127_1828996_2 Bacterial regulatory proteins, tetR family K09017 - - 0.000000000000000000000000000000000000001089 156.0
HFD3_k127_1839186_0 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000002326 214.0
HFD3_k127_1839186_1 (Rhomboid) family - - - 0.0000000653 63.0
HFD3_k127_1839226_0 PhoPQ-activated pathogenicity-related protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 487.0
HFD3_k127_1839226_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 427.0
HFD3_k127_1839226_2 Belongs to the peptidase S8 family K14645,K20754 - 3.4.21.111 0.0000004367 57.0
HFD3_k127_1839777_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000006148 242.0
HFD3_k127_1839777_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000001692 109.0
HFD3_k127_1839777_2 Elongator protein 3, MiaB family, Radical SAM K03644 - 2.8.1.8 0.00000000000000000000000205 103.0
HFD3_k127_1843057_1 Tetratricopeptide repeat - - - 0.000000003678 66.0
HFD3_k127_1843057_2 cell redox homeostasis - - - 0.0001416 44.0
HFD3_k127_1846401_0 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000003958 215.0
HFD3_k127_1846401_1 conserved protein, contains double-stranded beta-helix domain - - - 0.0000000000000000000000007858 103.0
HFD3_k127_1847831_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009191 280.0
HFD3_k127_1847831_1 PFAM amidohydrolase - - - 0.000000000000001184 81.0
HFD3_k127_1856193_0 transcription factor binding K15836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003082 251.0
HFD3_k127_1856193_1 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000003288 229.0
HFD3_k127_1856193_2 Major facilitator superfamily - - - 0.0000000000000000008093 90.0
HFD3_k127_185624_0 Sodium:sulfate symporter transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 371.0
HFD3_k127_185624_1 PQQ enzyme repeat - - - 0.0000000000000000000000000000000004583 146.0
HFD3_k127_1858930_0 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000004188 169.0
HFD3_k127_1858930_1 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000007734 174.0
HFD3_k127_1858930_2 Chorismate mutase type II - - - 0.00000000000000000000000982 104.0
HFD3_k127_1858930_3 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.000000000000000000005233 98.0
HFD3_k127_1860441_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000226 244.0
HFD3_k127_1860441_1 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001551 243.0
HFD3_k127_1860441_2 Response regulator, receiver K06147 - - 0.00000000000000000000000000000000004125 138.0
HFD3_k127_1862331_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000001242 203.0
HFD3_k127_1862331_1 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000005374 143.0
HFD3_k127_1862826_1 tail collar domain protein K21449 - - 0.00000000000000000000000000000000000000002536 171.0
HFD3_k127_1862826_3 Hep Hag repeat protein K09942,K21449 - - 0.0000000000001645 83.0
HFD3_k127_1863691_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006588 277.0
HFD3_k127_1863691_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.7.7.87 0.000000000000000000000000000000002827 131.0
HFD3_k127_1870749_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 376.0
HFD3_k127_1870749_1 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.000000000000000000000000000000000000001128 153.0
HFD3_k127_1876170_0 Fibronectin type III-like domain K05349 - 3.2.1.21 0.0 1058.0
HFD3_k127_1876170_1 PFAM ROK family - - - 0.000000000000000000000000000000000000000000000000000000000000000000003356 243.0
HFD3_k127_1876170_2 ligase activity - - - 0.00000000000000000000000001302 111.0
HFD3_k127_1876170_3 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0006809 48.0
HFD3_k127_1880319_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006618 423.0
HFD3_k127_1880319_1 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 323.0
HFD3_k127_1880319_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000008004 231.0
HFD3_k127_1880319_3 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000001091 212.0
HFD3_k127_1881845_0 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 306.0
HFD3_k127_1881845_1 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000000000000000000000000000000000000000000011 194.0
HFD3_k127_1881845_2 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 0.0000000000000000000000000000000000000000000007281 176.0
HFD3_k127_1889270_0 PFAM response regulator receiveR - - - 0.0000000000000000000000000000000000000000000000000000000000001129 216.0
HFD3_k127_1889270_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000003493 182.0
HFD3_k127_1891108_0 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006348 418.0
HFD3_k127_1891108_1 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001732 241.0
HFD3_k127_1915837_0 Acetyl xylan esterase (AXE1) - - - 3.137e-239 757.0
HFD3_k127_1915837_1 Zinc metalloprotease (Elastase) K20274 - - 0.00000000000000000000000000000000000000000000000000000000003646 233.0
HFD3_k127_1915837_2 lactoylglutathione lyase activity K11210,K21253,K21264,K21265 GO:0003674,GO:0003824,GO:0004364,GO:0008150,GO:0016740,GO:0016765,GO:0042221,GO:0046677,GO:0050896 2.5.1.18 0.000000000000000000000000000000000000000000003769 167.0
HFD3_k127_1915837_3 - - - - 0.000000000003621 71.0
HFD3_k127_1919687_0 Penicillin amidase K01434 - 3.5.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 462.0
HFD3_k127_1919687_1 Dystroglycan-type cadherin-like domains. - - - 0.00001001 55.0
HFD3_k127_1933928_0 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008672 484.0
HFD3_k127_1934271_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000001124 141.0
HFD3_k127_1934271_1 Domain of unknown function (DUF4288) - - - 0.00000000000000000000000000003598 121.0
HFD3_k127_1934271_2 Aldo/keto reductase family - - - 0.0000000000000000000000000009469 113.0
HFD3_k127_1934271_3 transporter - - - 0.00000003681 56.0
HFD3_k127_1934271_4 TRANSCRIPTIONal - - - 0.00000006228 54.0
HFD3_k127_1934749_0 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01431 - 3.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 427.0
HFD3_k127_1934749_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 410.0
HFD3_k127_1934749_2 Hydroxymethylglutaryl-coenzyme A reductase K00021 - 1.1.1.34 0.000000000003528 67.0
HFD3_k127_1936237_0 PFAM Alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 314.0
HFD3_k127_1936237_1 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000002158 100.0
HFD3_k127_1936237_2 antisigma-factor antagonist K04749 - - 0.0000003517 57.0
HFD3_k127_1936237_3 Belongs to the peptidase S8 family K14645 - - 0.00002651 53.0
HFD3_k127_1939002_0 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005255 285.0
HFD3_k127_1942338_0 Major facilitator superfamily K08151 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 430.0
HFD3_k127_1942338_1 dihydrofolate reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003939 258.0
HFD3_k127_1942338_2 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000003766 205.0
HFD3_k127_1942338_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000009066 194.0
HFD3_k127_1942338_4 DoxX-like family - - - 0.0000000000000000000000000000000000000000000002783 172.0
HFD3_k127_1942338_5 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000005393 163.0
HFD3_k127_1942338_6 Glyoxalase-like domain K07032 - - 0.000000000000000000000000000001104 126.0
HFD3_k127_1942338_7 - - - - 0.0000000000000006696 78.0
HFD3_k127_1942338_8 Pyridoxamine 5'-phosphate oxidase - - - 0.000000009088 59.0
HFD3_k127_1942338_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000006704 57.0
HFD3_k127_1945993_0 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000004031 217.0
HFD3_k127_1946479_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 386.0
HFD3_k127_1946479_1 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000002585 230.0
HFD3_k127_1946479_2 tigr00255 - - - 0.000000000000000000000000000000000000000000000000000000000000002498 228.0
HFD3_k127_1946479_3 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000001418 200.0
HFD3_k127_1946479_4 Transcription factor zinc-finger - - - 0.00000000000000000000000000000000000000000000000000007972 192.0
HFD3_k127_1946479_5 COGs COG1132 ABC-type multidrug transport system ATPase and permease components K11085 - - 0.0000000000000000000000000001024 117.0
HFD3_k127_1946479_6 YbbR-like protein - - - 0.0000000000000001424 91.0
HFD3_k127_1946479_7 DNA-directed 5'-3' RNA polymerase activity K03060 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.00009889 48.0
HFD3_k127_1950268_0 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005153 289.0
HFD3_k127_1956678_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 4.295e-215 677.0
HFD3_k127_1956678_1 Alcohol dehydrogenase zinc-binding domain protein K07119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 446.0
HFD3_k127_1956678_2 S4 RNA-binding domain - - - 0.000000000000006477 77.0
HFD3_k127_1961298_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 447.0
HFD3_k127_1961298_1 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000006193 237.0
HFD3_k127_1961298_2 SMART alpha amylase, catalytic sub domain - - - 0.000000000000000000000000000000000000000000103 166.0
HFD3_k127_1961298_3 Belongs to the 'phage' integrase family K04763 - - 0.0000000036 62.0
HFD3_k127_1971106_0 Protein of unknown function (DUF1572) - - - 0.00000000000000000000002478 106.0
HFD3_k127_1971106_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000009303 98.0
HFD3_k127_1972864_0 PFAM malic K00027,K00029 - 1.1.1.38,1.1.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 469.0
HFD3_k127_1986259_0 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 321.0
HFD3_k127_1986259_1 helix_turn_helix ASNC type K03719 - - 0.000000000000000000000000000000000000000000000000000001495 196.0
HFD3_k127_1986259_2 tRNA pseudouridine synthase - - - 0.0000000000000000000000000000000000000000000000000009007 187.0
HFD3_k127_1987214_0 Domain of unknown function (DUF4010) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003604 369.0
HFD3_k127_1987214_1 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000004665 213.0
HFD3_k127_1987214_2 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000002358 199.0
HFD3_k127_1987214_3 Tautomerase enzyme - - - 0.0000000002337 62.0
HFD3_k127_1988977_0 FtsX-like permease family K02004 - - 2.123e-292 917.0
HFD3_k127_1988977_1 HlyD family secretion protein K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 329.0
HFD3_k127_1988977_2 PFAM ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000009042 190.0
HFD3_k127_1988977_3 Universal stress protein - - - 0.0000000537 63.0
HFD3_k127_1989613_0 Transcriptional regulator - - - 0.00000000000000000000000000000000000000001134 162.0
HFD3_k127_199618_0 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008207 370.0
HFD3_k127_199618_1 radical SAM domain protein - - - 0.00000000000000000000000000000000001602 146.0
HFD3_k127_199618_2 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000001845 128.0
HFD3_k127_1996835_0 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000001057 168.0
HFD3_k127_1998620_0 TIGRFAM metallophosphoesterase, MG_246 BB_0505 family K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 306.0
HFD3_k127_2002879_0 Sensor diguanylate cyclase, GAF domain-containing - - - 0.00000000000000000000000000006674 129.0
HFD3_k127_2004971_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1052.0
HFD3_k127_2004971_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 421.0
HFD3_k127_2004971_2 Transcriptional regulatory protein, C terminal K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 296.0
HFD3_k127_2004971_3 ABC transporter K11953,K15579 - - 0.000000005963 58.0
HFD3_k127_2004971_4 Histidine kinase-like ATPases - - - 0.0000003982 61.0
HFD3_k127_2004971_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000934 48.0
HFD3_k127_2016192_0 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 523.0
HFD3_k127_2016192_1 ABC-type proline glycine betaine transport K05847 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 331.0
HFD3_k127_2016192_2 Histidine-specific methyltransferase, SAM-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006668 295.0
HFD3_k127_2018719_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000001325 248.0
HFD3_k127_2018719_1 ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000008115 223.0
HFD3_k127_2018719_2 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000000000000000000000000000000000004157 217.0
HFD3_k127_2018719_3 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000002579 138.0
HFD3_k127_20200_0 PFAM Glycoside hydrolase family 42 domain protein K12308 - 3.2.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006585 550.0
HFD3_k127_20200_1 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 466.0
HFD3_k127_20200_2 SMART Tetratricopeptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 414.0
HFD3_k127_20200_3 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 379.0
HFD3_k127_2023565_0 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000002128 134.0
HFD3_k127_2023565_1 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000000003992 120.0
HFD3_k127_2023565_2 Phosphoribosyl transferase domain - - - 0.000000000000000000000000006485 120.0
HFD3_k127_2023565_3 TonB-dependent Receptor Plug Domain - - - 0.00000001291 61.0
HFD3_k127_2027031_1 Belongs to the CinA family K03742 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000005513 232.0
HFD3_k127_2030897_0 Participates in initiation and elongation during chromosome replication K02314 GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 1.312e-266 847.0
HFD3_k127_2030897_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000009872 151.0
HFD3_k127_2031499_0 ATP-dependent transcriptional regulator, MalT-like, LuxR family K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 498.0
HFD3_k127_2031499_1 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 363.0
HFD3_k127_2031499_2 shikimate kinase activity K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000000000000000000000000001095 225.0
HFD3_k127_203439_0 PFAM TonB-dependent Receptor Plug - - - 0.0 1275.0
HFD3_k127_203439_1 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide - - - 5.696e-288 906.0
HFD3_k127_2038925_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003086 353.0
HFD3_k127_2038925_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000001709 92.0
HFD3_k127_2040849_0 PFAM Tetratricopeptide repeat - - - 0.000000000000000001848 98.0
HFD3_k127_2040849_1 - - - - 0.0000000002389 66.0
HFD3_k127_2040849_2 Centrosomin N-terminal motif 1 - GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005815,GO:0005816,GO:0005823,GO:0005856,GO:0015630,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044450,GO:0044464,GO:0044732,GO:0061493,GO:0071958,GO:0110092 - 0.000002512 61.0
HFD3_k127_2044798_0 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000666 245.0
HFD3_k127_2044798_1 PA domain - - - 0.0000000000000000000000000000000000003762 152.0
HFD3_k127_2048159_0 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 422.0
HFD3_k127_2048363_0 COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006687 444.0
HFD3_k127_2048363_1 PFAM N-acetylneuraminic acid synthase, N-terminal K01654 - 2.5.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 421.0
HFD3_k127_2048363_2 G-rich domain on putative tyrosine kinase K08252,K16554 - 2.7.10.1 0.0000000000000000000000000000000000000000000000000000000000000000007301 250.0
HFD3_k127_2048363_3 UDP-N-acetylglucosamine 2-epimerase K08068,K18429 - 3.2.1.183,3.2.1.184 0.00000000000000000000000000000000000000000000000000000000000007991 214.0
HFD3_k127_2055538_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 465.0
HFD3_k127_2056205_0 macromolecule localization K01992,K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004503 306.0
HFD3_k127_2056205_1 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001087 256.0
HFD3_k127_2056205_2 teichoic acid transport K01990,K09689,K09691 - 3.6.3.38 0.000000000009747 68.0
HFD3_k127_2057061_0 s cog3422 K09946 GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000003552 119.0
HFD3_k127_2057061_1 Sigma-54 interaction domain K07714 - - 0.00000000000000000000000001804 113.0
HFD3_k127_2062508_0 Belongs to the binding-protein-dependent transport system permease family K10559,K10561 - - 1.179e-268 842.0
HFD3_k127_2062508_1 Belongs to the binding-protein-dependent transport system permease family K10560 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 336.0
HFD3_k127_2065578_0 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 508.0
HFD3_k127_2065578_1 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000001325 246.0
HFD3_k127_2065578_2 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000001794 173.0
HFD3_k127_2065578_3 Protein involved in hydrolase activity K06889 - - 0.0000000000000000000000000000000002371 145.0
HFD3_k127_2065578_4 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.000000005303 58.0
HFD3_k127_207282_0 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000003046 217.0
HFD3_k127_2073648_0 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000001012 258.0
HFD3_k127_2073648_1 Glycosyl transferase family 4 K02851 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576 2.7.8.33,2.7.8.35 0.0000000000000000000968 99.0
HFD3_k127_2076898_0 COG0635 Coproporphyrinogen III oxidase and related Fe-S - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007058 533.0
HFD3_k127_2076898_1 COG0644 Dehydrogenases (flavoproteins) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 401.0
HFD3_k127_2076898_2 NHL repeat - - - 0.0000000000000000000000000000000000000000000000001326 181.0
HFD3_k127_2079040_0 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009097 451.0
HFD3_k127_2079962_0 AntiSigma factor - - - 0.000000000000000000000000000000000000000000329 169.0
HFD3_k127_2079962_1 Lactonase, 7-bladed beta-propeller - - - 0.000000000000000000000000000000000001983 153.0
HFD3_k127_2079962_2 PKD domain containing protein - - - 0.000000000009475 78.0
HFD3_k127_2079962_3 Belongs to the peptidase M10A family - - - 0.000002608 60.0
HFD3_k127_2084744_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000004096 253.0
HFD3_k127_2085308_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000009403 180.0
HFD3_k127_2086428_0 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 533.0
HFD3_k127_2086428_1 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001796 249.0
HFD3_k127_2088465_0 Amino acid permease K03294,K19540 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039 - 2.577e-195 616.0
HFD3_k127_2088465_1 PFAM TrkA-C domain protein K11105 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 514.0
HFD3_k127_2088567_0 Prolyl oligopeptidase family K01303 - 3.4.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 423.0
HFD3_k127_2088567_1 cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000004561 250.0
HFD3_k127_2092807_0 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007304 334.0
HFD3_k127_2092807_1 gluconolactonase activity K01053,K13735 - 3.1.1.17 0.000000000000000000000004086 105.0
HFD3_k127_2092807_2 AraC-like ligand binding domain - - - 0.000000000000000000001173 101.0
HFD3_k127_2097083_0 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 6.66e-321 1003.0
HFD3_k127_2097083_1 xanthine dehydrogenase activity - - - 6.605e-231 737.0
HFD3_k127_2097083_2 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 508.0
HFD3_k127_2097083_3 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000002323 187.0
HFD3_k127_2100298_0 Sortilin, neurotensin receptor 3, - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 430.0
HFD3_k127_2104942_0 Amidohydrolase family - - - 0.000000000000000000000000000006713 120.0
HFD3_k127_2104942_1 phosphorelay signal transduction system K02488,K04757 - 2.7.11.1,2.7.7.65 0.00000000000000000000001375 108.0
HFD3_k127_2107_0 - - - - 1.447e-220 705.0
HFD3_k127_2107_1 PQQ-like domain K05889 - 1.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005687 563.0
HFD3_k127_2107_2 carboxylic ester hydrolase activity K03929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007546 445.0
HFD3_k127_2107_3 Metal-dependent hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006205 377.0
HFD3_k127_2107_5 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000002128 129.0
HFD3_k127_2108277_0 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002727 307.0
HFD3_k127_2108277_1 response regulator - - - 0.000007308 50.0
HFD3_k127_2111835_0 Permease, YjgP YjgQ - - - 0.000000000000000000000000000000000000000000000000000000000000000000004371 261.0
HFD3_k127_2111835_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K04750 - - 0.000000000000000000000000000000000000002933 153.0
HFD3_k127_2115248_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 501.0
HFD3_k127_2115248_1 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002529 353.0
HFD3_k127_2115248_2 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000002964 147.0
HFD3_k127_2121743_0 Pyrrolo-quinoline quinone K00114 - 1.1.2.8 3.623e-290 901.0
HFD3_k127_2121743_1 PFAM extracellular solute-binding protein, family 3 K16254 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005476 325.0
HFD3_k127_2121743_2 PFAM Cytochrome C K00406 - - 0.000000000000000000000000000000000000000000000003249 179.0
HFD3_k127_2121743_3 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.00000000001396 73.0
HFD3_k127_2126146_0 membrane organization K07277,K09800 - - 0.0000000000000000000000000000000000000000000000000000000000000001689 252.0
HFD3_k127_2127097_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 331.0
HFD3_k127_2127097_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000004039 155.0
HFD3_k127_2128446_0 Caspase domain - - - 0.000000000000000000000000000000000000000005114 167.0
HFD3_k127_2128446_1 tetratricopeptide repeat - - - 0.00000000000000003256 93.0
HFD3_k127_2128506_0 Proposed nucleic acid binding domain - - - 4.168e-241 773.0
HFD3_k127_2128506_1 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000001458 170.0
HFD3_k127_2130689_0 Cell shape determining protein MreB Mrl K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006896 310.0
HFD3_k127_2130689_1 N-Acetylmuramoyl-L-alanine amidase K11066,K12287 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000005363 229.0
HFD3_k127_2130689_2 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000001544 209.0
HFD3_k127_2130689_3 serine threonine protein kinase K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.00000000000000000000000000000000000000000000000002668 196.0
HFD3_k127_2130689_4 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.000000000000000001024 92.0
HFD3_k127_2133692_0 PFAM peptidase M48 Ste24p - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 291.0
HFD3_k127_2133692_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000001759 164.0
HFD3_k127_2133692_2 transmembrane signaling receptor activity K03406 - - 0.00000000000000000000000000005496 121.0
HFD3_k127_2133692_3 domain, Protein - - - 0.00000000000000003223 91.0
HFD3_k127_2133692_4 S1/P1 Nuclease - - - 0.000000000000000556 81.0
HFD3_k127_2133692_5 S1/P1 Nuclease - - - 0.0000000006242 67.0
HFD3_k127_2136277_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 458.0
HFD3_k127_2136277_1 Belongs to the N(4) N(6)-methyltransferase family K00571 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 440.0
HFD3_k127_2136277_2 PFAM Phosphoglycerate mutase - - - 0.000000000000000000000000002824 120.0
HFD3_k127_2137207_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 538.0
HFD3_k127_2137681_0 (ABC) transporter K06147,K18890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007659 620.0
HFD3_k127_2137681_1 ABC transporter, transmembrane K18889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000739 595.0
HFD3_k127_2137681_2 - - - - 0.00000000000000000000000000000000000002737 151.0
HFD3_k127_2144878_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000002454 221.0
HFD3_k127_2144878_1 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000001446 160.0
HFD3_k127_2144878_2 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000003544 151.0
HFD3_k127_2144878_3 helix_turn_helix, arabinose operon control protein K07506 - - 0.000000000000000000000000000000196 134.0
HFD3_k127_2146943_0 Sodium:solute symporter family - - - 1.953e-205 649.0
HFD3_k127_2150794_0 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000001233 216.0
HFD3_k127_2152817_0 Fungal trichothecene efflux pump (TRI12) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 332.0
HFD3_k127_2152817_1 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000002777 179.0
HFD3_k127_2156361_0 - - - - 0.000000000000000000000000000000000000000000002007 169.0
HFD3_k127_2156361_1 - - - - 0.00000000000000000000000002015 115.0
HFD3_k127_2158663_0 Protein of unknown function (DUF979) - - - 0.0000000000000000000000000000000000000000000000000008821 191.0
HFD3_k127_2158663_1 ATP-grasp - - - 0.00000000000000000003041 93.0
HFD3_k127_2165025_0 cellulose binding - - - 3.8e-225 707.0
HFD3_k127_2165025_1 Sh3 type 3 domain protein - - - 0.00000000001662 76.0
HFD3_k127_2169769_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000006096 156.0
HFD3_k127_2169769_1 Calcineurin-like phosphoesterase - - - 0.00000000000000000005969 91.0
HFD3_k127_2178046_0 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0008199 48.0
HFD3_k127_2180393_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 8.227e-314 979.0
HFD3_k127_2180393_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 320.0
HFD3_k127_2180393_2 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000002093 228.0
HFD3_k127_2193049_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000402 219.0
HFD3_k127_2193049_1 - - - - 0.000000000000000000000000000000006089 135.0
HFD3_k127_2203129_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 452.0
HFD3_k127_2203129_1 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 325.0
HFD3_k127_2203129_2 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003476 272.0
HFD3_k127_2203129_3 FR47-like protein K18816 - 2.3.1.82 0.000000000000000000000000000000000009825 138.0
HFD3_k127_2204309_0 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007553 312.0
HFD3_k127_2204309_1 response regulator - - - 0.0000000000000000000005382 101.0
HFD3_k127_2204756_0 LVIVD repeat - - - 3.953e-288 910.0
HFD3_k127_2204756_1 Cytochrome c7 and related cytochrome c - - - 0.00000000004462 74.0
HFD3_k127_2204756_2 Cyclic nucleotide-monophosphate binding domain - - - 0.000002126 54.0
HFD3_k127_2204756_3 Class III cytochrome C family - - - 0.00001954 53.0
HFD3_k127_2204756_4 Cytochrome c554 and c-prime - - - 0.0003731 52.0
HFD3_k127_2206434_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007766 314.0
HFD3_k127_2210335_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009911 433.0
HFD3_k127_2210335_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007419 336.0
HFD3_k127_2210335_2 Preprotein translocase, YajC subunit K03210 - - 0.0000000000000000001443 93.0
HFD3_k127_2210335_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000007103 75.0
HFD3_k127_2212463_0 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007478 528.0
HFD3_k127_2217119_0 mannose-ethanolamine phosphotransferase activity K01077 GO:0003674,GO:0003824,GO:0004035,GO:0004346,GO:0005488,GO:0005575,GO:0005623,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008877,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046872,GO:0046914,GO:0050308,GO:0050309,GO:0098519 3.1.3.1 0.00000000000000000000000000000000000000000000000000000766 197.0
HFD3_k127_2217119_1 TPR repeat-containing protein - - - 0.0000001854 63.0
HFD3_k127_2232052_0 Peptidase family S51 K05995 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.13.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 288.0
HFD3_k127_2232052_1 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000005982 111.0
HFD3_k127_2232052_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000003681 98.0
HFD3_k127_2233728_0 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.00000000000000000000000000000000000000001506 164.0
HFD3_k127_2234368_0 succinyl-diaminopimelate desuccinylase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005707 426.0
HFD3_k127_2234368_1 succinyl-diaminopimelate desuccinylase activity - - - 0.000000000000000000000000003883 113.0
HFD3_k127_2234368_2 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000001048 98.0
HFD3_k127_2234368_3 PFAM Forkhead-associated protein - - - 0.0000000000000003318 89.0
HFD3_k127_2235071_0 PFAM AMP-dependent synthetase and ligase K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005899 333.0
HFD3_k127_2235071_1 RNA-binding protein containing a PIN domain K06962 - - 0.000000000000000000000000005366 115.0
HFD3_k127_2235573_0 - - - - 0.000000004625 67.0
HFD3_k127_2236824_0 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 409.0
HFD3_k127_2236824_1 PFAM Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000000000002176 200.0
HFD3_k127_2236824_2 PFAM Major Facilitator Superfamily K08223 - - 0.000000000000000000000000001412 117.0
HFD3_k127_2236824_3 abc-type fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.0000000000000000000001219 105.0
HFD3_k127_224092_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 367.0
HFD3_k127_2241677_0 Type VI secretion protein, EvpB/VC_A0108, tail sheath K11900 - - 3.5e-229 718.0
HFD3_k127_2241677_1 type VI secretion protein, VC_A0114 family K11893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 345.0
HFD3_k127_2241677_2 Protein conserved in bacteria K11902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001985 265.0
HFD3_k127_2241677_3 Protein of avirulence locus involved in temperature-dependent protein secretion K03217,K11898 - - 0.00000000000000000000000000000000000000000000000000000000000000000002817 242.0
HFD3_k127_2241677_4 type VI secretion protein K11901 - - 0.00000000000000000000000000000000000000000000000000000000006175 209.0
HFD3_k127_2241677_5 Type VI secretion system effector, Hcp K11903 - - 0.000000000000000000000000000000000000000000000000000003226 194.0
HFD3_k127_2243085_0 Baseplate J-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003077 279.0
HFD3_k127_2243085_1 GPW gp25 family protein K06903 - - 0.000000000000000000000000000000000000000000004898 166.0
HFD3_k127_2243704_0 PFAM glycoside hydrolase, family 29 K01206 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000082 533.0
HFD3_k127_2243704_1 Alginate lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 361.0
HFD3_k127_2243704_2 Pkd domain containing protein K07407 - 3.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 301.0
HFD3_k127_226305_0 Heparinase II/III N-terminus - - - 1.205e-254 804.0
HFD3_k127_226305_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 511.0
HFD3_k127_226305_2 Phenylacetate--CoA ligase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007005 499.0
HFD3_k127_226305_3 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 476.0
HFD3_k127_226305_4 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004734 299.0
HFD3_k127_226305_5 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000009019 144.0
HFD3_k127_226305_6 Bacterial sugar transferase - - - 0.0000000789 55.0
HFD3_k127_227980_0 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000002959 219.0
HFD3_k127_227980_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000002192 179.0
HFD3_k127_2279842_0 phosphatase homologous to the C-terminal domain of histone macroH2A1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009449 245.0
HFD3_k127_2279842_1 PFAM Endonuclease Exonuclease phosphatase K07004 - - 0.00000000000000000000000000000000000000703 164.0
HFD3_k127_2279842_2 Hep Hag repeat protein K11904,K21449 - - 0.000000000000000000000005406 108.0
HFD3_k127_2279842_3 Hhip-like - - - 0.0005617 48.0
HFD3_k127_228246_0 Heparinase II/III N-terminus - - - 0.0000000000000000000000000000000000000000000000000001237 198.0
HFD3_k127_228246_1 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.00008646 55.0
HFD3_k127_2289613_0 PFAM Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008805 376.0
HFD3_k127_2289613_1 Ferric uptake regulator family K09825 - - 0.00000000000000000000000000000001452 131.0
HFD3_k127_2289613_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000001051 77.0
HFD3_k127_229166_0 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000002207 221.0
HFD3_k127_229166_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000003374 165.0
HFD3_k127_229166_2 Belongs to the ClpA ClpB family K03696 - - 0.000000000000000000000000000000001529 138.0
HFD3_k127_229166_3 Fe-S cluster K04488 - - 0.00000000000000000000000000531 113.0
HFD3_k127_229166_4 Double zinc ribbon - - - 0.00003438 51.0
HFD3_k127_2298633_0 Mo-molybdopterin cofactor metabolic process K03148,K03636,K21029,K21147 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.73,2.7.7.80,2.8.1.11 1.265e-196 625.0
HFD3_k127_2298633_1 Belongs to the cysteine synthase cystathionine beta- synthase family K12339,K21148 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113,2.5.1.47 0.0000000000000000000000000000000000000000000000001466 179.0
HFD3_k127_2298633_2 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.00000000000000000000000000000005534 130.0
HFD3_k127_2298633_3 FAD linked oxidases, C-terminal domain K00102,K00104 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.2.4,1.1.3.15 0.0000000000000000000000001001 111.0
HFD3_k127_2305001_0 PFAM phosphoesterase, PA-phosphatase related - - - 0.00000000000000000000000000000000000000000000000002856 192.0
HFD3_k127_2305001_1 Phosphate acyltransferases K01897 - 6.2.1.3 0.0000000000000000001237 91.0
HFD3_k127_2307931_0 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 514.0
HFD3_k127_2307931_1 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000000000000000000000000000000000000000575 244.0
HFD3_k127_2324878_0 Tetratricopeptide repeats - - - 0.000000000000001358 85.0
HFD3_k127_2324878_1 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000007086 61.0
HFD3_k127_2332038_0 Alpha-L-fucosidase K01206 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000416 572.0
HFD3_k127_2332038_1 RND efflux system, outer membrane lipoprotein - - - 0.000000002306 68.0
HFD3_k127_2333117_0 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 437.0
HFD3_k127_2333117_1 SH3, type 3 domain protein - - - 0.0000000000000000000003424 104.0
HFD3_k127_233371_0 TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter K01537 - 3.6.3.8 9.991e-245 764.0
HFD3_k127_233371_1 FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000003285 162.0
HFD3_k127_2334084_0 iron-nicotianamine transmembrane transporter activity - - - 1.491e-252 795.0
HFD3_k127_2334084_1 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000384 181.0
HFD3_k127_2338824_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005469 354.0
HFD3_k127_2338824_1 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000126 198.0
HFD3_k127_2338824_2 enterobactin catabolic process K07214 - - 0.00000000000000000000000000000000000000000000000002193 193.0
HFD3_k127_2338824_3 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000001096 133.0
HFD3_k127_2338824_4 YceI-like domain - - - 0.0000000000000001061 89.0
HFD3_k127_2350265_0 Glycoside hydrolase family 44 - - - 8.395e-245 767.0
HFD3_k127_235394_0 Heparinase II/III-like protein - - - 0.00000000000000000000000000000008843 144.0
HFD3_k127_235394_1 - - - - 0.0005435 52.0
HFD3_k127_236071_0 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006981 453.0
HFD3_k127_236071_1 PFAM Peptidase M16 inactive domain K07263 - - 0.000000000000000000000000000000109 145.0
HFD3_k127_2364582_0 PQQ-like domain K00114 - 1.1.2.8 3.992e-227 715.0
HFD3_k127_2364582_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000003995 241.0
HFD3_k127_237600_0 O-Antigen ligase K02847 - - 0.00000000000000000000000000000000000000000000000000397 198.0
HFD3_k127_237600_1 Acyl-CoA dehydrogenase, C-terminal domain K00248,K00249 - 1.3.8.1,1.3.8.7 0.00000000000000000000000000000000000017 145.0
HFD3_k127_237600_2 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.000000000002967 75.0
HFD3_k127_237600_3 repeat-containing protein - - - 0.00001708 57.0
HFD3_k127_2383767_0 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 385.0
HFD3_k127_2383767_1 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000001459 211.0
HFD3_k127_2383767_2 Hep Hag repeat protein K11904,K21449 - - 0.00000015 58.0
HFD3_k127_2390508_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007042 595.0
HFD3_k127_2390508_1 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02031,K02032,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009583 405.0
HFD3_k127_2390508_2 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001012 271.0
HFD3_k127_2390508_3 PTS system fructose IIA component K02793,K02794,K02821 - 2.7.1.191,2.7.1.194 0.00000000000000000000000000000001484 131.0
HFD3_k127_2398309_0 myo-inosose-2 dehydratase activity K03335,K15652 - 4.2.1.118,4.2.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 312.0
HFD3_k127_2398309_1 Highly conserved protein containing a thioredoxin domain K18581 - 3.2.1.180 0.00000000000000000000000000000000000000000000007438 172.0
HFD3_k127_2407800_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 339.0
HFD3_k127_2407800_1 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 325.0
HFD3_k127_2407800_2 PFAM sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000004046 222.0
HFD3_k127_240995_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 3.319e-241 752.0
HFD3_k127_240995_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 412.0
HFD3_k127_2412489_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 371.0
HFD3_k127_2412489_1 - - - - 0.00000000000004248 79.0
HFD3_k127_2414860_0 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 513.0
HFD3_k127_2414860_1 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 434.0
HFD3_k127_2414860_2 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960,K20810 - 3.5.4.28,3.5.4.31,3.5.4.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 362.0
HFD3_k127_2414860_3 Amidohydrolase family K01465,K06015 - 3.5.1.81,3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000006508 232.0
HFD3_k127_2421422_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 408.0
HFD3_k127_2421422_1 Leucine Rich Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000009624 233.0
HFD3_k127_2421422_2 - - - - 0.00004337 46.0
HFD3_k127_242363_0 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000001029 102.0
HFD3_k127_242363_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00004431 56.0
HFD3_k127_2428260_0 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 320.0
HFD3_k127_2428260_1 Protein phosphatase 2C - - - 0.000000000000000000000000000000000000000000000000000000000000008209 231.0
HFD3_k127_2428260_2 translation initiation factor activity K01256 - 3.4.11.2 0.000001866 52.0
HFD3_k127_2434457_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 430.0
HFD3_k127_2444025_0 iron-sulfur binding K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 565.0
HFD3_k127_2444025_1 PFAM Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000747 175.0
HFD3_k127_244598_0 - - - - 0.000000000001345 75.0
HFD3_k127_2447044_0 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000001548 265.0
HFD3_k127_2447044_1 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000005776 189.0
HFD3_k127_2447044_2 Peptidase family M50 - - - 0.0000000000000000000000000005727 127.0
HFD3_k127_2447101_0 dehydrogenases and related proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 535.0
HFD3_k127_2447101_1 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005523 417.0
HFD3_k127_2447101_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000235 198.0
HFD3_k127_2450861_0 Putative auto-transporter adhesin, head GIN domain - - - 0.000000000000001358 85.0
HFD3_k127_2451504_0 cellulose binding - - - 0.0 1047.0
HFD3_k127_2451504_1 argininosuccinate lyase K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 441.0
HFD3_k127_2469447_0 Polysaccharide biosynthesis/export protein K01991 - - 0.00000000000000000000000488 115.0
HFD3_k127_2469447_1 Lipid A core-O-antigen ligase-like enyme K18814 - - 0.000000000000000003153 91.0
HFD3_k127_2469447_2 Chain length determinant protein - - - 0.00000001146 65.0
HFD3_k127_2469447_3 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.00001614 53.0
HFD3_k127_2469479_0 Catalyzes the cleavage of the C5-C6 bond of 2-hydroxy-6- oxononadienedioate and 2-hydroxy-6-oxononatrienedioate, a dienol ring fission product of the bacterial meta-cleavage pathway for degradation of phenylpropionic acid K05714 - 3.7.1.14 0.0000000000000000000000000000000000000000000000000008921 196.0
HFD3_k127_2469479_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000007223 59.0
HFD3_k127_2469479_2 SnoaL-like domain - - - 0.00000003596 63.0
HFD3_k127_2471969_0 Belongs to the ompA family - - - 0.00000000000000000000000000000004568 134.0
HFD3_k127_2471969_1 Methyltransferase type 11 - - - 0.0000000000000000000000000000166 122.0
HFD3_k127_2476594_0 Trehalose utilisation K08685 - 1.4.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004933 421.0
HFD3_k127_2476594_1 Alpha/beta hydrolase family - - - 0.000000000000004256 86.0
HFD3_k127_2476777_0 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006135 317.0
HFD3_k127_2476777_1 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004595 262.0
HFD3_k127_2476777_2 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000008641 186.0
HFD3_k127_248147_0 WD40-like Beta Propeller K03641 - - 0.0000000000000000000000000000000000000000000000000000000000001258 229.0
HFD3_k127_248147_1 PFAM MotA TolQ ExbB proton channel K03562 - - 0.00000000000000000000000000000000000000000004355 169.0
HFD3_k127_248147_2 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.00000000000000000000000000009705 123.0
HFD3_k127_248147_3 protein kinase activity - - - 0.000000002159 66.0
HFD3_k127_248147_4 TIGRFAM TonB family K03832 - - 0.0009411 50.0
HFD3_k127_2484326_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000001316 144.0
HFD3_k127_2484326_1 PFAM ResB family protein K07399 - - 0.0000000000000000000000000000004886 139.0
HFD3_k127_2484326_2 PFAM Cytochrome c assembly protein - - - 0.000000001468 69.0
HFD3_k127_2485259_0 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000004207 254.0
HFD3_k127_2485259_1 Two component regulator three Y - - - 0.000000000000000000000000000000000000000003425 179.0
HFD3_k127_2485259_2 - - - - 0.00005127 46.0
HFD3_k127_2485259_3 Opioid growth factor receptor (OGFr) conserved region - - - 0.0008668 42.0
HFD3_k127_248638_0 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 2.828e-261 825.0
HFD3_k127_248638_1 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004881 427.0
HFD3_k127_248638_2 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000293 271.0
HFD3_k127_2488738_0 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 316.0
HFD3_k127_2488738_1 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003081 267.0
HFD3_k127_2488738_2 dihydrofolate reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001233 242.0
HFD3_k127_2488738_3 Dienelactone hydrolase family - - - 0.0002916 46.0
HFD3_k127_2493724_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003165 249.0
HFD3_k127_2493724_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001189 232.0
HFD3_k127_2493724_2 - - - - 0.0000000000000000000000000000000005759 134.0
HFD3_k127_2498363_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K15727 - - 0.00000000000000000000000000000000000000000000000000000000005226 220.0
HFD3_k127_2498363_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K15725 - - 0.00000000000000000000000000000000000000000000002062 189.0
HFD3_k127_2504218_0 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005275 520.0
HFD3_k127_2504218_1 DinB superfamily - - - 0.000000000000000000000000000009917 123.0
HFD3_k127_2504218_2 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000001976 109.0
HFD3_k127_2504218_3 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000001998 85.0
HFD3_k127_2504433_0 PFAM peptidase K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 340.0
HFD3_k127_2505033_0 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005116 539.0
HFD3_k127_2505033_1 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000001694 194.0
HFD3_k127_2511624_0 cellulose binding - - - 3.2e-252 808.0
HFD3_k127_2511624_1 Repeat of unknown function (DUF346) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003612 262.0
HFD3_k127_2511624_2 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000000006621 209.0
HFD3_k127_2523776_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 306.0
HFD3_k127_2524892_0 Fibronectin type 3 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006314 494.0
HFD3_k127_2535423_0 Transposase DDE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 531.0
HFD3_k127_2537901_0 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000003919 161.0
HFD3_k127_2537901_1 dTDP biosynthetic process K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000001207 133.0
HFD3_k127_2537901_2 cellulose binding - - - 0.000003882 58.0
HFD3_k127_2539308_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008021 568.0
HFD3_k127_2539308_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 475.0
HFD3_k127_2541300_0 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009911 597.0
HFD3_k127_2541300_1 transport - - - 0.00000000000000000000000000000002022 130.0
HFD3_k127_2541300_2 TIGRFAM TIGR03032 family protein - - - 0.0000000000000068 87.0
HFD3_k127_254516_0 serine threonine protein kinase K12132 - 2.7.11.1 3.249e-217 709.0
HFD3_k127_254516_1 Tricorn protease homolog - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 291.0
HFD3_k127_2550067_0 Belongs to the heme-copper respiratory oxidase family K02274 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 605.0
HFD3_k127_2550067_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003244 297.0
HFD3_k127_2550067_2 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000004408 244.0
HFD3_k127_2550067_3 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000001295 240.0
HFD3_k127_2550067_4 heme a metabolic process K02259,K03110 - - 0.00000000000000000000000000000000000001139 156.0
HFD3_k127_2550067_5 PFAM cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000008523 154.0
HFD3_k127_2552644_0 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006705 311.0
HFD3_k127_2552644_1 TIGRFAM riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000005038 205.0
HFD3_k127_2552644_2 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000001111 203.0
HFD3_k127_2552644_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000008322 52.0
HFD3_k127_2558871_0 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009464 580.0
HFD3_k127_2558871_1 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001507 277.0
HFD3_k127_2559364_1 Cupin 2, conserved barrel domain protein K18991 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009438,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019243,GO:0019249,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046185,GO:0046394,GO:0051596,GO:0061727,GO:0071704,GO:0072330,GO:1901575,GO:1901576,GO:1901615,GO:1901617 - 0.000000000000000000000001949 108.0
HFD3_k127_2559364_3 periplasmic or secreted lipoprotein - - - 0.00000001973 63.0
HFD3_k127_2560632_0 Pfam Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000006138 203.0
HFD3_k127_2564665_0 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009096 516.0
HFD3_k127_2564665_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000484 332.0
HFD3_k127_2564665_2 response regulator K02477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001785 246.0
HFD3_k127_2564665_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000009474 164.0
HFD3_k127_2565232_0 Dual specificity phosphatase, catalytic domain - - - 0.000000000000003484 84.0
HFD3_k127_2565247_0 Domain of unknown function (DUF5069) - - - 0.0000000000000000000000000000009437 125.0
HFD3_k127_2565247_1 HNH nucleases - - - 0.0000000009356 60.0
HFD3_k127_2577269_0 ArgK protein K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 336.0
HFD3_k127_2577269_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000001421 221.0
HFD3_k127_2577269_2 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000002588 176.0
HFD3_k127_2577269_3 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000000000000000000000001271 168.0
HFD3_k127_2577269_4 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759,K05606 - 4.4.1.5,5.1.99.1 0.0000000000000000000000000000000000000003581 154.0
HFD3_k127_2577269_5 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000001227 139.0
HFD3_k127_2577269_6 SurA N-terminal domain K03769,K07533 - 5.2.1.8 0.0000000000000000000000000000002028 138.0
HFD3_k127_257994_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 578.0
HFD3_k127_257994_1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00263 - 1.4.1.9 0.0000000000000000000000000000000000000000000000000002684 188.0
HFD3_k127_257994_2 Domain of unknown function (DUF4437) - - - 0.00000000000000000000000000000000318 134.0
HFD3_k127_2583155_0 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 616.0
HFD3_k127_2583155_1 Fungalysin/Thermolysin Propeptide Motif K08603 - 3.4.24.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000004764 282.0
HFD3_k127_2583975_0 Protein of unknown function (DUF1501) - - - 1.569e-252 785.0
HFD3_k127_2589924_0 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000006052 171.0
HFD3_k127_260614_0 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 615.0
HFD3_k127_260614_1 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 312.0
HFD3_k127_260614_2 TIGRFAM polymorphic outer membrane protein K21449 - - 0.0000000000009867 76.0
HFD3_k127_260614_3 Cupin 2, conserved barrel domain protein - - - 0.00000000001686 71.0
HFD3_k127_2611446_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000001125 209.0
HFD3_k127_2611991_0 Sh3 type 3 domain protein K04772,K08372,K22278 - 3.5.1.104 0.000000000000000000004231 107.0
HFD3_k127_2611991_1 Domain of unknown function (DUF4384) - - - 0.0003546 51.0
HFD3_k127_2611991_3 Caspase domain - - - 0.0008945 50.0
HFD3_k127_2612641_0 Dihydroorotate dehydrogenase K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006867 340.0
HFD3_k127_2612641_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000002052 143.0
HFD3_k127_261693_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 358.0
HFD3_k127_261693_1 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000000000002065 223.0
HFD3_k127_2619392_0 PFAM SpoVR family protein K06415 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006415 547.0
HFD3_k127_2619392_1 Domain of unknown function (DUF4184) - - - 0.0000000000000000000000000004158 124.0
HFD3_k127_2620377_0 RNA-directed DNA polymerase (Reverse transcriptase) K00986 - 2.7.7.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009069 608.0
HFD3_k127_2620377_1 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 299.0
HFD3_k127_2620377_2 PFAM alpha beta hydrolase fold K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000005115 184.0
HFD3_k127_2621946_0 Amidohydrolase family - - - 9.932e-245 781.0
HFD3_k127_2627485_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 357.0
HFD3_k127_2627485_1 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004392 350.0
HFD3_k127_2628138_0 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000002258 228.0
HFD3_k127_2628138_1 Molybdenum Cofactor Synthesis C K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.0000000000000000000000000000000000000000004582 162.0
HFD3_k127_2628138_2 - - - - 0.000000000000000000000000000000000000000325 153.0
HFD3_k127_2631952_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009586 499.0
HFD3_k127_2631952_1 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009138 478.0
HFD3_k127_2631952_2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 367.0
HFD3_k127_2631952_3 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000007169 214.0
HFD3_k127_2631952_4 Putative metallopeptidase - - - 0.000000000001281 69.0
HFD3_k127_2632354_0 phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 419.0
HFD3_k127_2632354_1 very-long-chain-acyl-CoA dehydrogenase activity K17880,K18817 - 2.7.1.119,2.7.1.163 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006169 347.0
HFD3_k127_2632354_2 PFAM ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000004551 168.0
HFD3_k127_2632354_4 PFAM Uncharacterised protein family UPF0150 K18843 - - 0.0000000000000000000000000000007293 122.0
HFD3_k127_2632354_5 HicA toxin of bacterial toxin-antitoxin, K07339 - - 0.00000000000000000000000000008688 116.0
HFD3_k127_2632354_6 Belongs to the 'phage' integrase family K03733,K04763 - - 0.000006373 49.0
HFD3_k127_2643613_0 signal sequence binding K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007688 291.0
HFD3_k127_2643613_1 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000000000000000000001751 97.0
HFD3_k127_2643613_2 - - - - 0.0000002489 58.0
HFD3_k127_2655870_0 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 567.0
HFD3_k127_2655870_1 protein related to plant photosystem II stability assembly factor - - - 0.000001398 59.0
HFD3_k127_2658482_0 Tyrosine phosphatase family - - - 0.0000000000000004558 85.0
HFD3_k127_2664028_0 Transketolase, pyrimidine binding domain K00167 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001138 273.0
HFD3_k127_2664028_1 Contains PIN domain - - - 0.00000000000000000000000000000000000000000001252 164.0
HFD3_k127_2664028_2 Uncharacterised protein family (UPF0175) - - - 0.000000000000000000000000001395 113.0
HFD3_k127_2664028_3 - - - - 0.000000000000000000000826 102.0
HFD3_k127_2664028_4 Contains PIN domain - - - 0.00000004266 58.0
HFD3_k127_2664028_5 Transketolase, pyrimidine binding domain K00167,K11381,K21417 - 1.2.4.4 0.0000002234 52.0
HFD3_k127_2665415_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000008003 117.0
HFD3_k127_2675371_0 Zinc-binding dehydrogenase K13979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 567.0
HFD3_k127_2675371_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005602 287.0
HFD3_k127_2675507_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008984 326.0
HFD3_k127_2675507_1 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001063 261.0
HFD3_k127_2675507_2 HAD-hyrolase-like K07025 - - 0.000000000000000000000000000001218 130.0
HFD3_k127_2675507_3 - - - - 0.0000000000009391 77.0
HFD3_k127_2675507_4 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000007618 68.0
HFD3_k127_2675507_5 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine - - - 0.00000001183 61.0
HFD3_k127_2676081_0 Polysaccharide deacetylase K01452 - 3.5.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000001216 269.0
HFD3_k127_2676081_1 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000002 151.0
HFD3_k127_2676081_2 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000006696 85.0
HFD3_k127_2676081_3 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0001727 45.0
HFD3_k127_2679271_0 formate dehydrogenase K00127,K08350 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009326,GO:0009987,GO:0015942,GO:0015944,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0020037,GO:0022900,GO:0031224,GO:0031226,GO:0032787,GO:0032991,GO:0033554,GO:0036397,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0051716,GO:0052738,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.0000000000000000000000000000000000000000009478 167.0
HFD3_k127_2679271_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000006156 107.0
HFD3_k127_2681576_0 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 372.0
HFD3_k127_2681576_1 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000000000000000000001455 195.0
HFD3_k127_2681576_2 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.0000000000000000000000000000000007579 148.0
HFD3_k127_2681576_3 Bacterial membrane protein YfhO - - - 0.0000000000000000000006611 106.0
HFD3_k127_2681743_0 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 599.0
HFD3_k127_2692130_0 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006749 296.0
HFD3_k127_2692130_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004377 312.0
HFD3_k127_2692130_10 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000001927 77.0
HFD3_k127_2692130_11 xylan catabolic process K03932 - - 0.0000179 55.0
HFD3_k127_2692130_2 LytTr DNA-binding domain K02477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002059 259.0
HFD3_k127_2692130_3 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000006378 267.0
HFD3_k127_2692130_4 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000006329 203.0
HFD3_k127_2692130_5 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000000000003732 175.0
HFD3_k127_2692130_6 Domain of unknown function (DUF5050) K03641 - - 0.000000000000000000000000000000000000003118 158.0
HFD3_k127_2692130_7 TIGRFAM squalene-associated FAD-dependent desaturase - - - 0.0000000000000000000000000000000000009464 147.0
HFD3_k127_2692130_8 hydrolase of the alpha beta superfamily K07017 - - 0.0000000000000000000000000000003221 141.0
HFD3_k127_2692130_9 Putative phosphatase (DUF442) - - - 0.0000000000000000001469 97.0
HFD3_k127_2695198_0 ABC transporter K10441 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007781 457.0
HFD3_k127_2695198_1 ABC-type sugar transport system periplasmic component K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009766 285.0
HFD3_k127_2699165_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 479.0
HFD3_k127_2699165_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 388.0
HFD3_k127_2699165_2 Inorganic pyrophosphatase K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 297.0
HFD3_k127_2699165_3 TIGRFAM galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006991 284.0
HFD3_k127_2699165_4 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000003957 233.0
HFD3_k127_2699165_5 GrpB protein - - - 0.00000000000000000000000000000000000000004978 157.0
HFD3_k127_2699463_0 ferrous iron transmembrane transporter activity K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006853 471.0
HFD3_k127_2699463_1 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000000000000000003104 197.0
HFD3_k127_2699463_2 - - - - 0.0000000000000000000000000000000002257 135.0
HFD3_k127_2699463_3 FeoA K04758 - - 0.00000000001978 67.0
HFD3_k127_2699463_4 Heavy-metal resistance - - - 0.00007975 52.0
HFD3_k127_27044_0 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000884 462.0
HFD3_k127_2706709_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 4.982e-216 684.0
HFD3_k127_2706709_1 Tetratricopeptide repeat - - - 0.00001086 54.0
HFD3_k127_2707390_0 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 492.0
HFD3_k127_2707390_1 beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 288.0
HFD3_k127_2714482_0 PFAM Archaeal ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007877 410.0
HFD3_k127_2714482_1 AAA-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008578 392.0
HFD3_k127_2714482_2 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000002506 268.0
HFD3_k127_2714482_3 DNA-templated transcription, initiation K02405 - - 0.0000000000000000000000000000000000002476 143.0
HFD3_k127_2714482_4 WD domain, G-beta repeat - GO:0002244,GO:0002376,GO:0002520,GO:0007275,GO:0008150,GO:0009987,GO:0030097,GO:0030154,GO:0032501,GO:0032502,GO:0048513,GO:0048534,GO:0048731,GO:0048856,GO:0048869 - 0.00000000000000000000000156 120.0
HFD3_k127_2730550_0 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000002391 106.0
HFD3_k127_2730550_1 Bacterial regulatory protein, Fis family - - - 0.000000000000742 72.0
HFD3_k127_2730550_2 PFAM Colicin V production protein K03558 - - 0.00000006044 61.0
HFD3_k127_2731579_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008598 411.0
HFD3_k127_2731579_1 Histidine kinase - - - 0.000000002209 62.0
HFD3_k127_27338_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005984 370.0
HFD3_k127_27338_1 Putative esterase K07214 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 306.0
HFD3_k127_27338_2 Enoyl-CoA hydratase/isomerase K01692,K13766 - 4.2.1.17,4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003222 276.0
HFD3_k127_27338_3 Dioxygenase K00449 - 1.13.11.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000004742 261.0
HFD3_k127_27338_4 Thioredoxin - - - 0.00000000000000000000176 99.0
HFD3_k127_2734068_0 Domain of unknown function DUF87 K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 344.0
HFD3_k127_2734068_1 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000000000000000000000000689 179.0
HFD3_k127_2734068_2 Thioredoxin-like - - - 0.00000000000000000000000000000002442 132.0
HFD3_k127_2734068_3 Protein involved in meta-pathway of phenol degradation - - - 0.000000000102 74.0
HFD3_k127_2747776_0 Glycosyl hydrolase family 9 K01179 - 3.2.1.4 2.079e-251 797.0
HFD3_k127_2747776_1 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001258 269.0
HFD3_k127_2747776_2 Beta-lactamase - - - 0.0000000000000000371 83.0
HFD3_k127_2750227_0 Wd40 repeat-containing protein - - - 0.000000000000001371 85.0
HFD3_k127_2750227_1 Protein of unknown function (DUF3500) - - - 0.0000000000005248 69.0
HFD3_k127_2773733_0 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 2.438e-315 982.0
HFD3_k127_2773733_1 sequence-specific DNA binding K01697,K01738 GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363 2.5.1.47,4.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 519.0
HFD3_k127_2773733_2 - - - - 0.000000009875 67.0
HFD3_k127_2775371_0 Pfam Beta-galactosidase trimerisation domain K12308 - 3.2.1.23 1.909e-267 841.0
HFD3_k127_2775371_1 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000006465 215.0
HFD3_k127_2775371_2 Tetratricopeptide repeat K12132 - 2.7.11.1 0.0000000000000009428 78.0
HFD3_k127_2775798_0 Belongs to the enoyl-CoA hydratase isomerase family K01692 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004731 303.0
HFD3_k127_2775798_1 Domain of unknown function (DUF4956) - - - 0.0000000007282 68.0
HFD3_k127_2779225_0 Belongs to the glycosyl hydrolase 28 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003571 529.0
HFD3_k127_2779225_1 FCD K05799 - - 0.00000000000000000000000000000000000000000000000000000000000000000009837 241.0
HFD3_k127_2784069_0 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 550.0
HFD3_k127_2784069_1 Belongs to the ATCase OTCase family K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0043857,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 333.0
HFD3_k127_2784069_2 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000000001674 210.0
HFD3_k127_2788578_0 SMART Tetratricopeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007255 407.0
HFD3_k127_2788578_1 COG3392 Adenine-specific DNA methylase K07318 - 2.1.1.72 0.00000000000000000000000005126 110.0
HFD3_k127_280021_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 315.0
HFD3_k127_280021_1 protease with the C-terminal PDZ domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002378 266.0
HFD3_k127_280021_2 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000000000000000000000002294 199.0
HFD3_k127_280021_3 DoxX K15977 - - 0.0000000000000000000000000000000000000000007 161.0
HFD3_k127_280021_4 Alpha beta K06889 - - 0.000000000000000000003563 105.0
HFD3_k127_280021_5 Belongs to the UPF0312 family - - - 0.000003583 49.0
HFD3_k127_2800284_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000004992 192.0
HFD3_k127_2800284_1 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.00000000000000000000000000003786 122.0
HFD3_k127_2803424_0 domain protein K02238 - - 0.00000000000000000000000000000000000000000000000000000000056 214.0
HFD3_k127_2803424_1 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000001257 82.0
HFD3_k127_2803424_2 Protein of unknown function (DUF3006) - - - 0.0000478 49.0
HFD3_k127_280506_0 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.000000000000000000000000000000000000000000000000000000000000000001953 239.0
HFD3_k127_2806123_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006886 602.0
HFD3_k127_2809046_0 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000001692 85.0
HFD3_k127_2809046_1 HD domain - - - 0.00000000000001091 85.0
HFD3_k127_280945_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000007498 180.0
HFD3_k127_280945_1 PBS lyase HEAT-like repeat - - - 0.00000000000000000000000000001129 132.0
HFD3_k127_280945_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000005137 123.0
HFD3_k127_280945_3 PBS lyase HEAT-like repeat - - - 0.0000000000000001226 93.0
HFD3_k127_2810960_0 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 367.0
HFD3_k127_2810960_1 GDP-mannose mannosyl hydrolase activity K01515,K03574,K12944 - 3.6.1.13,3.6.1.55 0.0000000000001726 82.0
HFD3_k127_2814666_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 6.324e-229 723.0
HFD3_k127_2818854_0 Belongs to the IlvD Edd family K01687,K22186 - 4.2.1.82,4.2.1.9 1.64e-210 662.0
HFD3_k127_2818854_1 Alginate lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 543.0
HFD3_k127_2818854_2 Periplasmic binding protein domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 311.0
HFD3_k127_283_0 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000003572 264.0
HFD3_k127_283_1 Redoxin - - - 0.000000000000000000000000000000000000000000007284 167.0
HFD3_k127_2833523_0 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K02003 - - 0.000000000000000000000000000000000000000000000000000000001906 203.0
HFD3_k127_2833523_1 Domain of unknown function (DUF4198) - - - 0.00002568 49.0
HFD3_k127_283411_0 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000002573 211.0
HFD3_k127_283411_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000002045 168.0
HFD3_k127_283411_2 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000003331 158.0
HFD3_k127_283411_3 Helix-hairpin-helix domain K02347 - - 0.0000000000000000000000000142 115.0
HFD3_k127_2842466_0 ABC-2 type transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000814 308.0
HFD3_k127_2842466_1 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000002304 219.0
HFD3_k127_2853505_0 Pyrimidine nucleoside phosphorylase C-terminal domain K00756,K00758 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2,2.4.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 454.0
HFD3_k127_2853505_1 Asparaginase K01424,K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.1,3.5.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 367.0
HFD3_k127_2853505_2 acetylesterase activity - - - 0.0000000000000004085 81.0
HFD3_k127_2855857_0 Thioredoxin - - - 0.0000000000000000000006018 110.0
HFD3_k127_2855857_1 YCII-related domain - - - 0.000000000000000000002888 96.0
HFD3_k127_2855857_2 Sigma-70 region 2 K03088 - - 0.00000000000000000005573 94.0
HFD3_k127_2861607_0 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 329.0
HFD3_k127_2861607_1 PFAM transposase mutator type K07493 - - 0.0000006516 51.0
HFD3_k127_2862277_0 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 402.0
HFD3_k127_2862277_1 Uncharacterized conserved protein (DUF2203) - - - 0.00000000000000000000000000007225 120.0
HFD3_k127_2862277_2 Bacterial DNA-binding protein K03530 - - 0.00000000000000000000000005108 111.0
HFD3_k127_2862277_3 FAD dependent oxidoreductase - - - 0.00000000000000000000000007928 107.0
HFD3_k127_2862277_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000121 64.0
HFD3_k127_2862600_0 sh3 domain protein - - - 0.0000000007017 65.0
HFD3_k127_2868647_0 Zinc carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003867 246.0
HFD3_k127_2868647_1 Methyltransferase K08316 - 2.1.1.171 0.000000000000000000000002543 107.0
HFD3_k127_2869608_0 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003746 548.0
HFD3_k127_2869608_1 FAD dependent oxidoreductase K15736 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006549 533.0
HFD3_k127_2869608_2 aromatic amino acid beta-eliminating lyase threonine aldolase - - - 0.0000000000000000000000000000005715 126.0
HFD3_k127_2869608_3 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.000000000004817 65.0
HFD3_k127_2870575_0 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 463.0
HFD3_k127_2870575_1 oxidoreductase activity K00274 - 1.4.3.4 0.0000000000000000000000000000000000000000000000000001115 192.0
HFD3_k127_2870575_2 Beta-lactamase K17836 - 3.5.2.6 0.0000000000000000000000000000001449 136.0
HFD3_k127_2870575_3 Gram-negative bacterial TonB protein C-terminal - - - 0.000001283 58.0
HFD3_k127_2870600_0 Protein kinase domain K12132 - 2.7.11.1 4.114e-216 700.0
HFD3_k127_2870600_1 Type I secretion membrane fusion protein, HlyD K11003,K12532 - - 0.000006976 50.0
HFD3_k127_2872428_0 - - - - 0.0000000000000775 76.0
HFD3_k127_288154_0 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 341.0
HFD3_k127_288154_1 Hydrophobe amphiphile Efflux-1 (HAE1) family K03296,K18138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003181 273.0
HFD3_k127_2887286_0 Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000000004722 88.0
HFD3_k127_2887286_1 prohibitin homologues - - - 0.000000000000008187 79.0
HFD3_k127_2887286_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.000004681 57.0
HFD3_k127_2892099_0 PFAM periplasmic binding protein LacI transcriptional regulator K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 394.0
HFD3_k127_2892099_1 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004863 268.0
HFD3_k127_2892099_2 Major Facilitator Superfamily - - - 0.0000000000000000001182 96.0
HFD3_k127_2894554_0 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 497.0
HFD3_k127_2898532_0 ABC transporter transmembrane region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003653 434.0
HFD3_k127_2898532_1 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002995 260.0
HFD3_k127_2899163_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 582.0
HFD3_k127_2899163_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system - - - 0.000000000000003364 81.0
HFD3_k127_2900677_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006799 530.0
HFD3_k127_2900677_1 virion core protein (lumpy skin disease virus) - - - 0.0000000003237 61.0
HFD3_k127_2913775_0 PFAM aminotransferase, class I K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 393.0
HFD3_k127_2913775_1 PFAM Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 345.0
HFD3_k127_2913775_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000004721 208.0
HFD3_k127_2913775_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000002732 192.0
HFD3_k127_2922605_0 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002911 291.0
HFD3_k127_2922605_1 Histidine kinase K02478 - 2.7.13.3 0.00000000006466 69.0
HFD3_k127_2922657_0 FR47-like protein - - - 0.00000000000000000000000000000000000000000000000123 177.0
HFD3_k127_2922657_1 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000007282 156.0
HFD3_k127_2928648_0 spermidine synthase activity K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 349.0
HFD3_k127_2928648_1 Tetratricopeptide repeat - - - 0.00003251 57.0
HFD3_k127_2933553_0 flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase - - - 0.0000000000000000000000000000000000000001138 154.0
HFD3_k127_2934678_0 Peptidase M14, carboxypeptidase A - - - 0.0 1092.0
HFD3_k127_2934678_1 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000007114 138.0
HFD3_k127_2934678_2 PFAM isocitrate isopropylmalate dehydrogenase K00030,K07246 - 1.1.1.41,1.1.1.83,1.1.1.93,4.1.1.73 0.00000000000000000006381 91.0
HFD3_k127_294085_0 H( )-stimulated, divalent metal cation uptake system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 332.0
HFD3_k127_294085_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 - 2.7.6.5,3.1.7.2 0.000000000000000002882 90.0
HFD3_k127_2949462_0 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007756 344.0
HFD3_k127_2949462_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 340.0
HFD3_k127_2949462_2 PFAM Glycosyl transferase family 2 - - - 0.0000000006833 62.0
HFD3_k127_2956164_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 347.0
HFD3_k127_2956164_1 Peptidase family C25 - - - 0.000000000000000000000008675 117.0
HFD3_k127_2956164_2 Transcriptional regulator - - - 0.00000005488 66.0
HFD3_k127_2961107_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 606.0
HFD3_k127_2961107_1 Methyltransferase type 11 - - - 0.00000000000000000000000000006781 120.0
HFD3_k127_2965133_0 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007746 408.0
HFD3_k127_2965133_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003515 264.0
HFD3_k127_2965133_2 Putative carbohydrate binding domain K12373 - 3.2.1.52 0.00000000001858 68.0
HFD3_k127_2965192_0 Involved in the heme and chlorophyll biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000005702 256.0
HFD3_k127_2965192_1 Zinc carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000002191 215.0
HFD3_k127_2965192_2 Tyrosine phosphatase family - - - 0.0000000000000000000000000000000000000001604 157.0
HFD3_k127_2965192_3 Tyrosine phosphatase family - - - 0.0000000000000000000000001386 114.0
HFD3_k127_297857_0 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008109 392.0
HFD3_k127_297857_1 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000412 266.0
HFD3_k127_297857_2 Belongs to the glycosyl hydrolase 26 family - - - 0.0000000000000003578 88.0
HFD3_k127_2978945_0 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008255 436.0
HFD3_k127_2978945_1 ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000001447 260.0
HFD3_k127_2987073_0 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 490.0
HFD3_k127_2987073_1 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 481.0
HFD3_k127_2987073_2 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 316.0
HFD3_k127_2987073_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000002186 181.0
HFD3_k127_2999775_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006525 460.0
HFD3_k127_2999775_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993,K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003322 320.0
HFD3_k127_2999775_2 ABC transporter K02003,K09814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008383 285.0
HFD3_k127_3006167_0 PFAM glycoside hydrolase family 39 K01198 - 3.2.1.37 8.656e-249 779.0
HFD3_k127_3006167_1 PFAM Transposase - - - 0.0000000000000000000000000000000000000000000000000006176 188.0
HFD3_k127_301243_0 Phosphoglycerate kinase K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 480.0
HFD3_k127_301243_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000227 279.0
HFD3_k127_301243_2 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000003082 224.0
HFD3_k127_301243_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000533 98.0
HFD3_k127_301243_4 Preprotein translocase SecG subunit K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0000004286 57.0
HFD3_k127_3015926_0 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02481,K11384 - - 0.000000000000008867 78.0
HFD3_k127_3017669_0 and related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 482.0
HFD3_k127_3017669_1 ABC-type sugar transport system periplasmic component K10439 - - 0.000000000000000005415 87.0
HFD3_k127_3031328_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 2.76e-197 630.0
HFD3_k127_3037094_0 Belongs to the amidase family K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000497 550.0
HFD3_k127_3037094_1 PFAM AMP-dependent synthetase and ligase K00666,K01897,K02182,K22133 - 6.2.1.3,6.2.1.48,6.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005346 400.0
HFD3_k127_3037094_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000006274 244.0
HFD3_k127_3042423_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 9.145e-201 635.0
HFD3_k127_3042423_1 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000000000000000000000106 224.0
HFD3_k127_3042423_2 Bacterial membrane protein YfhO - - - 0.00000000000000000000000000000002521 146.0
HFD3_k127_3042423_3 Fibronectin type 3 domain - - - 0.000000000000000000001072 108.0
HFD3_k127_3042423_4 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000007259 53.0
HFD3_k127_3042580_0 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.000000000000000000000000000003354 138.0
HFD3_k127_3042580_1 amino acid transport K03294 - - 0.00000000000000000000000000001731 122.0
HFD3_k127_304546_0 Transcriptional regulator K06921 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 507.0
HFD3_k127_304546_1 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000001753 239.0
HFD3_k127_3045659_0 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005398 417.0
HFD3_k127_3045659_1 Transmembrane and TPR repeat-containing protein - - - 0.00000000000000001203 94.0
HFD3_k127_3046871_0 nitrate reductase beta subunit K00371 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0033554,GO:0042126,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 554.0
HFD3_k127_3046871_1 TIGRFAM respiratory nitrate reductase, gamma subunit K00374 - 1.7.5.1 0.0000000000000000000000000001668 119.0
HFD3_k127_3046871_2 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.00000000000000000000002858 106.0
HFD3_k127_3049281_0 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000497 311.0
HFD3_k127_3049281_1 Roadblock/LC7 domain - - - 0.000000000000000000000000000000000000000000000000000007603 193.0
HFD3_k127_3049281_2 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000002567 188.0
HFD3_k127_3049281_3 NIPSNAP - - - 0.000006978 48.0
HFD3_k127_3056119_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 473.0
HFD3_k127_3056119_1 enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000001911 207.0
HFD3_k127_3056119_2 TIGRFAM cytochrome C family protein - - - 0.00009716 53.0
HFD3_k127_3058000_0 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 1.844e-202 636.0
HFD3_k127_3058000_1 endo-1,4-beta-xylanase activity K01181 - 3.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000001033 270.0
HFD3_k127_3058497_0 PFAM NAD-dependent epimerase dehydratase K01709 - 4.2.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 351.0
HFD3_k127_3058497_1 Nucleotidyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 304.0
HFD3_k127_3058497_2 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000006597 162.0
HFD3_k127_3058497_3 Glycosyltransferase Family 4 - - - 0.0004795 46.0
HFD3_k127_3063471_0 Nucleotidyl transferase - - - 0.0000000000000000000000000000000000000000000000003229 187.0
HFD3_k127_3063471_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000763 183.0
HFD3_k127_3063471_2 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase - - - 0.0000000000000347 84.0
HFD3_k127_306437_0 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009157 361.0
HFD3_k127_3071479_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 578.0
HFD3_k127_3071479_1 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000342 229.0
HFD3_k127_3071479_2 cAMP biosynthetic process - - - 0.0000000000000000000000001813 112.0
HFD3_k127_3073219_0 Thiolase, C-terminal domain K00632 - 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 522.0
HFD3_k127_3073219_1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K07516 - 1.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004692 392.0
HFD3_k127_3073219_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009251 363.0
HFD3_k127_3076452_0 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.0000000000000007347 91.0
HFD3_k127_3077315_0 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 315.0
HFD3_k127_3077315_1 Virulence activator alpha C-term - - - 0.0000000000000000000000000000000000000000000003065 177.0
HFD3_k127_3077315_2 NAD dependent epimerase dehydratase family - - - 0.0000000000000000000001366 109.0
HFD3_k127_3080015_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 5.695e-305 951.0
HFD3_k127_3080015_1 Anthranilate synthase K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006924 274.0
HFD3_k127_3080015_2 Belongs to the TrpC family K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000001445 205.0
HFD3_k127_3080015_3 protein possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000000008927 131.0
HFD3_k127_3086416_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 316.0
HFD3_k127_3086416_1 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000002331 216.0
HFD3_k127_3086416_2 DinB family - - - 0.00000001421 61.0
HFD3_k127_3091599_0 Cyclomaltodextrinase, N-terminal K21575 - 3.2.1.135 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 611.0
HFD3_k127_3091599_1 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000002065 120.0
HFD3_k127_3105766_0 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000000000000000000000006908 128.0
HFD3_k127_3105766_1 Glycoprotease K14742 - - 0.00000000000003937 80.0
HFD3_k127_3105766_2 - - - - 0.000001654 57.0
HFD3_k127_311448_0 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005686 286.0
HFD3_k127_3116890_0 - - - - 0.0000000000000000000000000000000000000000000000000000002153 206.0
HFD3_k127_3116890_1 KR domain - - - 0.0000000000000000000000000000000000000000000000001727 187.0
HFD3_k127_3116890_2 PHB/PHA accumulation regulator DNA-binding domain - - - 0.00000000000000000000002465 108.0
HFD3_k127_3116890_3 - - - - 0.00000000329 66.0
HFD3_k127_311706_0 Patatin-like phospholipase K07001 GO:0003674,GO:0003824,GO:0016787 - 0.000000000000001101 87.0
HFD3_k127_3124853_0 PAS fold - - - 0.0000000000000000000002075 110.0
HFD3_k127_3124853_1 histone H2A K63-linked ubiquitination K04771,K07003 - 3.4.21.107 0.00000004816 58.0
HFD3_k127_3131473_0 Aminotransferase K10907 - - 0.0000000000000000000000000000000000000000000000000000000000003338 229.0
HFD3_k127_3131473_1 outer membrane autotransporter barrel domain protein - - - 0.000000000000000000000006182 105.0
HFD3_k127_314956_0 Oxidoreductase domain protein - - - 1.78e-208 654.0
HFD3_k127_314956_1 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process - - - 0.0000000000001011 80.0
HFD3_k127_314956_2 domain, Protein K03112 - - 0.00000000001167 74.0
HFD3_k127_3152662_0 - - - - 0.00000000000000000000000002998 113.0
HFD3_k127_3152662_1 Dehydrogenase E1 component K00164 - 1.2.4.2 0.0000000000000000000000005656 113.0
HFD3_k127_3153226_0 Cysteine synthase A K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 385.0
HFD3_k127_3153226_1 protein flavinylation K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000005786 227.0
HFD3_k127_3153226_2 Magnesium chelatase, subunit ChlI K03404,K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000426 199.0
HFD3_k127_3153226_3 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000001167 149.0
HFD3_k127_3153226_4 - - - - 0.000000000000000001951 87.0
HFD3_k127_3153931_0 pfam abc1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 347.0
HFD3_k127_3153931_1 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000007585 138.0
HFD3_k127_3156401_0 Belongs to the amidase family K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 587.0
HFD3_k127_3156401_1 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005995 347.0
HFD3_k127_3162282_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 396.0
HFD3_k127_3162282_1 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008681 333.0
HFD3_k127_3162282_2 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004254 326.0
HFD3_k127_3162282_3 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000001299 248.0
HFD3_k127_3162282_4 electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000112 237.0
HFD3_k127_3162282_5 Beta-lactamase - - - 0.000000000000000000000000000000000006339 142.0
HFD3_k127_3174845_0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000426 146.0
HFD3_k127_3174845_1 membrane organization K07277,K09800 - - 0.0007846 53.0
HFD3_k127_3174845_2 Bacterial protein of unknown function (DUF922) - - - 0.0008146 43.0
HFD3_k127_31803_0 TIGRFAM amino acid adenylation domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 586.0
HFD3_k127_3184942_0 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 289.0
HFD3_k127_3184942_1 thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.00000000000000000000000000000000000000000000000000000000001076 212.0
HFD3_k127_3184942_2 photosynthesis - - - 0.00000000000000000000000000000000000000000000000000006612 192.0
HFD3_k127_3184942_3 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000007256 190.0
HFD3_k127_3184942_4 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000007288 122.0
HFD3_k127_3184942_5 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000007746 82.0
HFD3_k127_3187681_0 D-arabinono-1,4-lactone oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006345 457.0
HFD3_k127_3187719_0 Cytochrome c - - - 1.586e-221 721.0
HFD3_k127_3187719_1 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001088 254.0
HFD3_k127_3188876_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 496.0
HFD3_k127_3188876_1 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000001066 224.0
HFD3_k127_3188876_2 MCM2/3/5 family K03924 - - 0.0000000000000000000000000008708 116.0
HFD3_k127_3199904_0 ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 529.0
HFD3_k127_3199904_1 PFAM Glycosyl transferases group 1 K12995 - 2.4.1.348 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 357.0
HFD3_k127_3199904_2 Glycosyltransferase family 28 C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 316.0
HFD3_k127_3199904_3 Heparinase II/III N-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000005637 224.0
HFD3_k127_3199904_4 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000002229 181.0
HFD3_k127_3199904_5 Acid phosphatase homologues - - - 0.000000000000000000000000000000000000000007669 166.0
HFD3_k127_3200319_0 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000001448 247.0
HFD3_k127_3200319_1 Ami_2 - - - 0.00000000000139 79.0
HFD3_k127_3200319_2 NHL repeat - - - 0.0000716 54.0
HFD3_k127_3200496_0 Haem-degrading - - - 0.00000000000000000000000000000000000000000000000000000000003241 220.0
HFD3_k127_3200496_1 tRNA 3'-trailer cleavage K00784,K01120 - 3.1.26.11,3.1.4.17 0.00000000000000000000000000000000000000000000000007298 186.0
HFD3_k127_3200496_2 - - - - 0.00000000000000000000000000002962 124.0
HFD3_k127_3204113_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 552.0
HFD3_k127_3204113_1 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000003673 100.0
HFD3_k127_3211756_0 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008924 481.0
HFD3_k127_3211756_1 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 357.0
HFD3_k127_3211756_2 NADPH quinone reductase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 338.0
HFD3_k127_3211756_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001997 260.0
HFD3_k127_3211756_4 PFAM OsmC family protein K04063 - - 0.000000000000000000000000000000000000000004278 157.0
HFD3_k127_3215992_0 Peptidase family C25 - - - 0.00000000000000000000000000000000000000000000000000000000000007923 240.0
HFD3_k127_3217365_0 Belongs to the peptidase S8 family K14645,K20754 - 3.4.21.111 0.00000000000000000000000000000000000000000000000000000000000000003051 231.0
HFD3_k127_3217365_1 S1/P1 Nuclease - - - 0.0000000000000000001929 100.0
HFD3_k127_3224626_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000009549 181.0
HFD3_k127_3224626_1 PD-(D/E)XK nuclease superfamily - - - 0.0000000000001424 80.0
HFD3_k127_322488_0 Ankyrin repeats (many copies) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009206 334.0
HFD3_k127_322488_1 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000001097 177.0
HFD3_k127_3226322_0 Ribosomal protein S1 K02945 - - 4.412e-204 652.0
HFD3_k127_3226322_1 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000001499 114.0
HFD3_k127_3227496_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007995 396.0
HFD3_k127_3227496_1 pyrroloquinoline quinone binding - - - 0.000000000000000000006683 96.0
HFD3_k127_3227496_2 H( )-stimulated, divalent metal cation uptake system - - - 0.000000000001675 71.0
HFD3_k127_3227496_3 Tetratricopeptide repeats - - - 0.000000005351 64.0
HFD3_k127_3227523_0 PFAM Type II secretion system F domain K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007706 309.0
HFD3_k127_3227523_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004833 277.0
HFD3_k127_3234237_0 - - - - 7.837e-194 620.0
HFD3_k127_3235422_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006641 327.0
HFD3_k127_3235422_1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000001469 193.0
HFD3_k127_3235422_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000004112 102.0
HFD3_k127_3237856_0 desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006365 355.0
HFD3_k127_3237856_1 myo-inosose-2 dehydratase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004107 326.0
HFD3_k127_3237856_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.0000000000000000000000000000000001429 137.0
HFD3_k127_323979_0 cytochrome p450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 534.0
HFD3_k127_323979_1 EVE domain - - - 0.000000191 59.0
HFD3_k127_3242212_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006494 321.0
HFD3_k127_3242212_1 D-glycero-D-manno-heptose 7-phosphate metabolic process K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 286.0
HFD3_k127_3242212_2 HAD-hyrolase-like K03273 - 3.1.3.82,3.1.3.83 0.00000000000002536 76.0
HFD3_k127_3272205_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008132 352.0
HFD3_k127_3272205_1 There are 9 addittional ORFs identical to this one - - - 0.000000000000000000000000000000000000000000000000000000000000001537 229.0
HFD3_k127_3272205_2 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000002004 160.0
HFD3_k127_3272205_3 DinB superfamily - - - 0.00000000000000000000000000000000000006006 149.0
HFD3_k127_3274301_0 Phage late control gene D protein (GPD) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 337.0
HFD3_k127_3275945_0 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000001446 211.0
HFD3_k127_3275945_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000009188 150.0
HFD3_k127_3281960_0 membrane protein, TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 396.0
HFD3_k127_3281960_1 Peptidase family C25 - - - 0.000000000000005703 79.0
HFD3_k127_3288179_0 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006142 392.0
HFD3_k127_3288940_0 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000001508 117.0
HFD3_k127_3288940_1 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.00000000000000002325 96.0
HFD3_k127_3290769_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 451.0
HFD3_k127_3290769_1 Peptidase family C69 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 359.0
HFD3_k127_3290769_2 Domain of unknown function (DUF4112) - - - 0.0000000000000000000000000003266 122.0
HFD3_k127_3290769_3 DedA family - - - 0.000000000001013 78.0
HFD3_k127_329500_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005143 297.0
HFD3_k127_329500_1 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000112 167.0
HFD3_k127_3310034_0 Enoyl-CoA hydratase/isomerase K01715,K07537 - 4.2.1.100,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 342.0
HFD3_k127_3310034_1 Caspase domain - - - 0.00000000000000000000000000000000000000000000000001174 203.0
HFD3_k127_3310034_2 - - - - 0.00000000000000000006551 97.0
HFD3_k127_3323297_0 Carboxyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 467.0
HFD3_k127_3323297_1 - - - - 0.00006615 51.0
HFD3_k127_3335540_0 Aromatic amino acid lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009899 549.0
HFD3_k127_3335885_0 PFAM Conserved region in glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 2.246e-312 983.0
HFD3_k127_3337552_0 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009708 513.0
HFD3_k127_3337552_1 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002818 274.0
HFD3_k127_3337552_2 Peptidase family C25 - - - 0.000000000000000000000000000000000000000000000000000000000000000001175 253.0
HFD3_k127_3337552_3 Carboxypeptidase regulatory-like domain - - - 0.00004116 48.0
HFD3_k127_3337552_4 Ethanolamine utilisation protein EutN/carboxysome - - - 0.0001422 45.0
HFD3_k127_3338895_0 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.0000000000000000000000000000000000000000000000000000000000000001414 226.0
HFD3_k127_3338895_1 Lysylphosphatidylglycerol synthase TM region - - - 0.000000000000000002221 96.0
HFD3_k127_3338895_2 - - - - 0.0000682 52.0
HFD3_k127_3361163_0 Peptidase M14, carboxypeptidase A - - - 0.0 1264.0
HFD3_k127_3361163_1 Trypsin-like peptidase domain - - - 0.0000000000000000000000000000002982 128.0
HFD3_k127_3371717_0 acetyltransferase - - - 0.00000000000000000000000000000000000000000000004693 173.0
HFD3_k127_337315_0 PrkA AAA domain protein K07180 - - 1.177e-246 769.0
HFD3_k127_337315_1 Belongs to the UPF0229 family K09786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 470.0
HFD3_k127_337315_2 PFAM SpoVR family protein K06415 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000376 332.0
HFD3_k127_3377617_0 Alpha-L-rhamnosidase N-terminal domain K05989 - 3.2.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 477.0
HFD3_k127_3386926_0 Tetratricopeptide repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003516 387.0
HFD3_k127_3386926_1 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000005244 160.0
HFD3_k127_3386926_2 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000005328 108.0
HFD3_k127_3392483_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005736 463.0
HFD3_k127_3392483_1 PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 439.0
HFD3_k127_3392483_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 380.0
HFD3_k127_3392483_3 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 300.0
HFD3_k127_3392483_4 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000002047 182.0
HFD3_k127_3392483_5 metallopeptidase activity K08738,K20276 - - 0.0000000000000000000000001881 118.0
HFD3_k127_3398750_0 TonB-dependent Receptor Plug K02014 - - 0.0000000000000000000000000000000000000000000000000000000001355 222.0
HFD3_k127_3398750_1 phosphoprotein phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000006869 205.0
HFD3_k127_3398750_2 - - - - 0.00000000003083 74.0
HFD3_k127_3406492_0 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 400.0
HFD3_k127_340904_0 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004337 281.0
HFD3_k127_340904_2 - - - - 0.0000000000000000000004792 108.0
HFD3_k127_3409897_0 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 373.0
HFD3_k127_3424077_0 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.0 1127.0
HFD3_k127_3424502_0 acyl-CoA dehydrogenase activity K00248,K00253 - 1.3.8.1,1.3.8.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 456.0
HFD3_k127_3424502_1 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000000001739 214.0
HFD3_k127_3424502_2 cAMP biosynthetic process K00870,K12132 - 2.7.1.37,2.7.11.1 0.00000000000000004172 88.0
HFD3_k127_3428923_0 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000006367 194.0
HFD3_k127_3428923_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000001418 171.0
HFD3_k127_3428923_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006183,GO:0006195,GO:0006204,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009125,GO:0009126,GO:0009127,GO:0009128,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009154,GO:0009156,GO:0009158,GO:0009161,GO:0009163,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009169,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009261,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046037,GO:0046039,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:0097292,GO:0097293,GO:1901068,GO:1901070,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 0.0000000002624 66.0
HFD3_k127_3429454_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000553 404.0
HFD3_k127_3429454_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01751,K01754,K06016,K17989,K21400 GO:0000287,GO:0003674,GO:0003824,GO:0003941,GO:0004793,GO:0004794,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006090,GO:0006464,GO:0006520,GO:0006549,GO:0006563,GO:0006565,GO:0006566,GO:0006567,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008838,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009071,GO:0009081,GO:0009082,GO:0009097,GO:0009987,GO:0016020,GO:0016053,GO:0016054,GO:0016597,GO:0016829,GO:0016830,GO:0016832,GO:0016840,GO:0016841,GO:0016853,GO:0016854,GO:0016855,GO:0017144,GO:0018249,GO:0019538,GO:0019752,GO:0019842,GO:0030170,GO:0030378,GO:0030848,GO:0031406,GO:0032787,GO:0036094,GO:0036211,GO:0036361,GO:0042219,GO:0042802,GO:0042803,GO:0042866,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046416,GO:0046437,GO:0046872,GO:0046983,GO:0047661,GO:0048037,GO:0050662,GO:0070178,GO:0070179,GO:0070279,GO:0071704,GO:0071944,GO:0072330,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.3.1.263,3.5.1.6,3.5.1.87,4.3.1.15,4.3.1.17,4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000712 394.0
HFD3_k127_3429454_2 Transcriptional regulator, LysR - - - 0.000000000000000000000000000000000139 141.0
HFD3_k127_3440990_0 Fungal family of unknown function (DUF1776) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 405.0
HFD3_k127_3440990_1 PFAM Alcohol dehydrogenase GroES-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 336.0
HFD3_k127_3440990_2 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000006572 226.0
HFD3_k127_3444422_0 GGDEF domain - - - 8.22e-200 651.0
HFD3_k127_3444422_1 proline dipeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 592.0
HFD3_k127_3444422_2 Sulfatase-modifying factor enzyme 1 K13444 - 1.8.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 331.0
HFD3_k127_3444422_3 Peptidase S9, prolyl oligopeptidase active site domain protein K01322 - 3.4.21.26 0.0000000000000000000000000000000000000000000000000000000000003311 214.0
HFD3_k127_3445464_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 414.0
HFD3_k127_3445464_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 368.0
HFD3_k127_3445464_2 homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 374.0
HFD3_k127_3445464_3 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 296.0
HFD3_k127_3445464_4 PFAM Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000001574 188.0
HFD3_k127_3445464_5 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000003611 158.0
HFD3_k127_3445464_6 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.0000000000000000000000000000000004963 138.0
HFD3_k127_3452086_0 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004606 553.0
HFD3_k127_3452086_1 DinB family - - - 0.00000000000000000000000000000002096 132.0
HFD3_k127_345631_0 DNAJ heat shock N-terminal domain-containing protein - - - 0.0002611 53.0
HFD3_k127_3459881_0 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000000000000000000006297 179.0
HFD3_k127_3459881_1 mttA/Hcf106 family K03116 - - 0.00000000000001609 79.0
HFD3_k127_3467450_0 COG2801 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007842 437.0
HFD3_k127_3467450_1 Chaperone of endosialidase - - - 0.000000006361 68.0
HFD3_k127_3467450_2 Adenylate cyclase - - - 0.0000001396 56.0
HFD3_k127_3467450_3 Hep Hag repeat protein - - - 0.000000181 64.0
HFD3_k127_3467764_0 protein kinase related protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 457.0
HFD3_k127_3467764_1 Mechanosensitive ion channel K05802 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 388.0
HFD3_k127_3467764_2 beta-propeller repeat - - - 0.000000000000000000007853 98.0
HFD3_k127_3471874_0 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005058 250.0
HFD3_k127_3471874_1 Ferric uptake regulator family K03711,K09825 - - 0.00000000000000000000000000002008 124.0
HFD3_k127_3474810_0 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 328.0
HFD3_k127_3474810_1 Chaperone of endosialidase - - - 0.0000000007721 68.0
HFD3_k127_3476628_0 C-terminal, D2-small domain, of ClpB protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 458.0
HFD3_k127_3476628_1 PFAM SNARE associated Golgi protein - - - 0.000000000000000000001535 102.0
HFD3_k127_3476628_2 Stage II sporulation protein K06381 - - 0.000000000000000000003481 104.0
HFD3_k127_3476628_3 Stage II sporulation protein K06381 - - 0.000000000000001477 83.0
HFD3_k127_3476939_0 phosphoesterase RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 394.0
HFD3_k127_3476939_1 Glycosyltransferase like family 2 K10012 - 2.4.2.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008309 377.0
HFD3_k127_3476939_2 Glycosyl transferase WecB/TagA/CpsF family K05946 - 2.4.1.187 0.0000000000000000000000000000000000000000000000000000000000000000002802 240.0
HFD3_k127_3476939_3 oxidoreductase activity K00274 - 1.4.3.4 0.000000000000000000000000000008022 128.0
HFD3_k127_3477376_0 molybdate ABC transporter, permease protein K02017,K02018 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000006993 245.0
HFD3_k127_3477376_1 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000003129 232.0
HFD3_k127_3477376_2 ATPase activity K02017 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000001727 192.0
HFD3_k127_3477376_3 Beta-lactamase - - - 0.00000000000000000000000000000000000003047 147.0
HFD3_k127_3477376_4 TOBE domain - - - 0.00000000000000000000000000008758 118.0
HFD3_k127_3478992_0 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000000000000000000000000000000000001254 153.0
HFD3_k127_3478992_1 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.0000000000000000000000000002296 118.0
HFD3_k127_3478992_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.0000000000000005323 79.0
HFD3_k127_3478992_3 Polysaccharide deacetylase - - - 0.0000000000007774 78.0
HFD3_k127_348260_0 spectrin binding - - - 0.0000000000123 76.0
HFD3_k127_3485304_0 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 596.0
HFD3_k127_3496811_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 417.0
HFD3_k127_3496811_1 DNA-templated transcription, initiation - - - 0.000000000000000000000000000001149 134.0
HFD3_k127_3496811_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000003984 121.0
HFD3_k127_350054_0 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 319.0
HFD3_k127_350054_1 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.0000000000000002396 85.0
HFD3_k127_3508774_0 thiolester hydrolase activity K06889 - - 0.000000000000000000000000000000000000000000001425 177.0
HFD3_k127_3508774_1 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000002458 109.0
HFD3_k127_3522008_0 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 601.0
HFD3_k127_3522008_1 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005365 316.0
HFD3_k127_3525339_0 glutathione-regulated potassium exporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000124 255.0
HFD3_k127_3525339_1 von Willebrand factor, type A - - - 0.0000004544 55.0
HFD3_k127_3529114_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666 - - 1.185e-224 710.0
HFD3_k127_3529114_1 major pilin protein fima - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008175 428.0
HFD3_k127_3529114_2 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001915 292.0
HFD3_k127_3529114_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000001483 174.0
HFD3_k127_3530708_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007055 275.0
HFD3_k127_3530708_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000001508 193.0
HFD3_k127_3538230_0 MacB-like periplasmic core domain - - - 5.404e-247 786.0
HFD3_k127_3538230_1 efflux transmembrane transporter activity - - - 1.723e-210 680.0
HFD3_k127_3538230_2 aminopeptidase activity - - - 0.000000000000001207 79.0
HFD3_k127_3538230_3 Beta-lactamase - - - 0.000000000000009246 74.0
HFD3_k127_3541159_0 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006033 360.0
HFD3_k127_3541159_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000005031 242.0
HFD3_k127_3541159_2 Bacterial regulatory proteins, tetR family - - - 0.000000000001625 69.0
HFD3_k127_3541159_3 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000005097 53.0
HFD3_k127_3541159_4 TIGRFAM Outer membrane assembly lipoprotein YfiO K05807 - - 0.000003599 55.0
HFD3_k127_3543849_0 Transcriptional regulator K03641 - - 0.0000000000000000000000000000000000001517 153.0
HFD3_k127_354527_0 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006522 491.0
HFD3_k127_354527_1 ABC transporter K02003,K05685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001508 248.0
HFD3_k127_354527_2 lipoprotein localization to outer membrane K02004 - - 0.000000000000000000000000000000000000000000000002249 188.0
HFD3_k127_3548594_0 tail specific protease - - - 0.00000000001282 70.0
HFD3_k127_3548594_1 peptidase activity - - - 0.00000001275 62.0
HFD3_k127_3548594_2 TonB-dependent receptor - - - 0.000002321 50.0
HFD3_k127_3549904_0 PFAM UDP-galactopyranose mutase, C-terminal K01854 - 5.4.99.9 1.193e-199 626.0
HFD3_k127_3549904_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 506.0
HFD3_k127_3549904_2 beta-glucosidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 494.0
HFD3_k127_3549904_3 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 376.0
HFD3_k127_3549904_4 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 377.0
HFD3_k127_3549904_5 COGs COG0596 hydrolase or acyltransferase (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000002125 189.0
HFD3_k127_3549904_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000001015 122.0
HFD3_k127_3549904_7 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.00000000000000000000000003594 122.0
HFD3_k127_3560346_0 Cadherin repeats. - - - 0.0000000000000000000000000000000000000000000000009862 196.0
HFD3_k127_35611_0 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 327.0
HFD3_k127_35611_1 ABC-type transport system involved in multi-copper enzyme maturation permease component - - - 0.00000000000000000000000283 113.0
HFD3_k127_3561752_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006372 490.0
HFD3_k127_356643_0 Glyoxalase-like domain K06996 - - 0.00000000000000000000000000000000000000000000000000001197 192.0
HFD3_k127_356643_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000001368 58.0
HFD3_k127_3568497_0 PFAM N-acetylneuraminic acid synthase K01654 - 2.5.1.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 452.0
HFD3_k127_3568497_1 Glycosyltransferase like family 2 - - - 0.000000133 63.0
HFD3_k127_3568640_0 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000006723 125.0
HFD3_k127_3568640_1 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 - - 0.00000000000000000000006832 115.0
HFD3_k127_3568640_2 PFAM Tetratricopeptide - - - 0.00001792 58.0
HFD3_k127_3569931_0 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007057 348.0
HFD3_k127_3574721_0 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007367 329.0
HFD3_k127_3574721_1 PFAM Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005306 294.0
HFD3_k127_3574721_2 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000000000000000000000000000000000005104 229.0
HFD3_k127_3574721_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000003836 204.0
HFD3_k127_357580_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 491.0
HFD3_k127_357580_1 DNA helicase K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000102 274.0
HFD3_k127_3577338_0 undecaprenyl-diphosphatase activity K06153 GO:0006950,GO:0008150,GO:0050896,GO:0051409 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 293.0
HFD3_k127_3577338_1 Histidine kinase - - - 0.000000000000000000000000000006712 128.0
HFD3_k127_3577338_2 - - - - 0.000003682 48.0
HFD3_k127_3577338_3 Belongs to the 'phage' integrase family - - - 0.0002378 45.0
HFD3_k127_3577338_4 COG1403 Restriction endonuclease - - - 0.0009014 46.0
HFD3_k127_3585893_0 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004702 598.0
HFD3_k127_3585893_1 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000006331 185.0
HFD3_k127_3592541_0 Domain of unknown function DUF87 K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000002163 227.0
HFD3_k127_3602870_0 Highly conserved protein containing a thioredoxin domain K18581 - 3.2.1.180 9.221e-249 785.0
HFD3_k127_3602870_1 PFAM Major Facilitator Superfamily K08191 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003293 540.0
HFD3_k127_3602870_2 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006267 348.0
HFD3_k127_3602870_3 enzyme involved in inositol metabolism K03337 - 5.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000003181 252.0
HFD3_k127_3602870_4 AraC-like ligand binding domain - - - 0.000000000000000004563 88.0
HFD3_k127_3603043_0 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000002548 248.0
HFD3_k127_3603043_1 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000008852 149.0
HFD3_k127_3603043_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000004899 112.0
HFD3_k127_3603726_0 Domain of unknown function (DUF4431) - - - 0.00000000000000005487 90.0
HFD3_k127_3603892_0 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 396.0
HFD3_k127_3603892_1 cellulose binding - - - 0.000000000000000000000000177 117.0
HFD3_k127_3604723_0 ABC-type multidrug transport system ATPase component K19340 - - 0.0000000000000000000000000000000000000000000001489 176.0
HFD3_k127_3604723_1 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000004049 143.0
HFD3_k127_3607572_0 metal cluster binding - - - 0.000000000000000000000000000000000000000000000000000000000000002621 226.0
HFD3_k127_3607572_1 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000001189 218.0
HFD3_k127_3607572_2 Protein of unknown function (DUF1211) - GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016043,GO:0022607,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0043933,GO:0044085,GO:0046873,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055085,GO:0065003,GO:0071804,GO:0071805,GO:0071840,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000001417 95.0
HFD3_k127_3607572_3 DNA-templated transcription, initiation K03088 - - 0.0004845 45.0
HFD3_k127_3607940_0 beta-glucosidase activity K05350 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004288 500.0
HFD3_k127_3607940_1 Glycosyl hydrolases family 43 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003879 292.0
HFD3_k127_3607940_2 Tetratricopeptide repeat - - - 0.0000000004211 70.0
HFD3_k127_3612153_0 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000002888 72.0
HFD3_k127_3612153_1 Fibronectin type 3 domain - - - 0.00000001594 62.0
HFD3_k127_3614490_0 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007245 460.0
HFD3_k127_3614490_1 PFAM Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 438.0
HFD3_k127_3614490_2 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000005303 142.0
HFD3_k127_3614490_3 PFAM aldo keto reductase - - - 0.0000001375 53.0
HFD3_k127_3614585_0 Penicillin amidase K01434 - 3.5.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 362.0
HFD3_k127_3614640_0 PFAM Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 295.0
HFD3_k127_3614640_1 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000008951 146.0
HFD3_k127_3614640_2 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000007972 139.0
HFD3_k127_3615303_0 Belongs to the ClpA ClpB family K03694 - - 5.09e-286 897.0
HFD3_k127_3615303_1 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009846 476.0
HFD3_k127_3615303_2 conserved protein (COG2071) K09166 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 310.0
HFD3_k127_3615303_3 - K07283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001777 275.0
HFD3_k127_3615303_4 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000005554 244.0
HFD3_k127_3615303_5 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000001462 168.0
HFD3_k127_3615303_6 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000002954 119.0
HFD3_k127_3618803_0 PFAM major facilitator superfamily MFS_1 K08151 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009208 383.0
HFD3_k127_3618803_1 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 318.0
HFD3_k127_3618803_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768,K01769 - 4.6.1.1,4.6.1.2 0.000000000000000000000000000000000002735 148.0
HFD3_k127_3618803_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00002911 49.0
HFD3_k127_3624942_0 Beta-lactamase K01256,K17836 - 3.4.11.2,3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007631 285.0
HFD3_k127_3624942_1 - - - - 0.00000000000000000000000000000000009997 138.0
HFD3_k127_3624942_2 PFAM Bacterial SH3 domain - - - 0.000000000000000000000000000004687 126.0
HFD3_k127_3624942_3 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K16363 - 3.5.1.108,4.2.1.59 0.0000639 48.0
HFD3_k127_3634256_0 peptidase activity, acting on L-amino acid peptides K07004,K09955 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008942 451.0
HFD3_k127_3634256_1 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000002786 213.0
HFD3_k127_3644441_0 DNA-K related protein - - - 1.128e-238 769.0
HFD3_k127_3644441_1 MreB/Mbl protein - - - 1.636e-233 737.0
HFD3_k127_3644441_2 Domain of unknown function (DUF2760) - - - 0.0000000000000000000002154 98.0
HFD3_k127_3650387_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 - 3.4.21.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 458.0
HFD3_k127_3650387_1 SMART Tetratricopeptide domain protein - - - 0.00000057 53.0
HFD3_k127_365498_0 choline dehydrogenase activity - - - 5.814e-273 849.0
HFD3_k127_365498_1 cellulase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 433.0
HFD3_k127_366221_0 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 295.0
HFD3_k127_366221_1 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000005169 171.0
HFD3_k127_366221_2 Tetratricopeptide repeat - - - 0.0000000000000009592 87.0
HFD3_k127_366221_3 Cupin 2, conserved barrel domain protein - - - 0.0000008588 53.0
HFD3_k127_3663841_0 TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007358 342.0
HFD3_k127_3665873_0 Tricorn protease PDZ domain K08676 - - 7.98e-219 702.0
HFD3_k127_3665873_1 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004778 289.0
HFD3_k127_3667984_0 pfkB family carbohydrate kinase K18478 - 2.7.1.184 0.00000000000000000000000000000000000000000000000000000000000000000000004752 248.0
HFD3_k127_3667984_1 Subtilase family - - - 0.0000000000000000000187 97.0
HFD3_k127_3673120_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 5.78e-199 625.0
HFD3_k127_3673120_1 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.00000000000000000000000000000000000000000000000000000000000000000253 228.0
HFD3_k127_3673459_0 Glycogen debranching enzyme, glucanotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 339.0
HFD3_k127_3673459_1 MFS/sugar transport protein K16211 - - 0.00000000000000000000000000000000007609 136.0
HFD3_k127_3681283_0 Domain of unknown function K03737 - 1.2.7.1 1.494e-247 771.0
HFD3_k127_3684160_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 496.0
HFD3_k127_3684160_1 pfam abc1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 368.0
HFD3_k127_3684160_2 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000578 294.0
HFD3_k127_3684160_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000003537 227.0
HFD3_k127_3684160_4 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000000000000000000000000000000000003836 184.0
HFD3_k127_3684160_5 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000005323 145.0
HFD3_k127_3684160_6 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000007613 128.0
HFD3_k127_368772_0 magnesium chelatase K03404,K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 425.0
HFD3_k127_368772_1 Oxidoreductase molybdopterin binding domain K00387,K07147 - 1.8.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009949 353.0
HFD3_k127_368772_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.000000000000001787 83.0
HFD3_k127_3688334_0 Tetratricopeptide repeat - - - 0.0000000000000000003966 100.0
HFD3_k127_368889_0 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 455.0
HFD3_k127_368889_1 - - - - 0.00001088 51.0
HFD3_k127_368889_2 DNA-templated transcription, initiation K02405 - - 0.0001032 45.0
HFD3_k127_3689650_0 lytic transglycosylase activity K03194 - - 0.0000000001844 73.0
HFD3_k127_3692614_0 F5/8 type C domain - - - 2.811e-209 673.0
HFD3_k127_3692614_1 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 476.0
HFD3_k127_3692614_2 inositol monophosphate 1-phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009393 405.0
HFD3_k127_3692614_3 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 GO:0003674,GO:0003824,GO:0004335,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006012,GO:0006793,GO:0006796,GO:0008108,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019200,GO:0019318,GO:0019320,GO:0019388,GO:0033499,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0046872,GO:0046914,GO:0070569,GO:0071704,GO:1901575 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000005915 261.0
HFD3_k127_3696260_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 445.0
HFD3_k127_3696260_1 oxidoreductase activity, acting on diphenols and related substances as donors K02636,K03886 - 1.10.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000002547 246.0
HFD3_k127_3696260_2 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins - - - 0.0000000000001918 73.0
HFD3_k127_3696260_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000004065 69.0
HFD3_k127_3696260_4 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.00000001223 57.0
HFD3_k127_3698119_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000716 370.0
HFD3_k127_3698119_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000126 295.0
HFD3_k127_3698119_2 Belongs to the glycosyl hydrolase 2 family K01192 - 3.2.1.25 0.00000000000000000000000000000000000000000001943 173.0
HFD3_k127_3703193_0 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 483.0
HFD3_k127_3703193_1 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000001277 131.0
HFD3_k127_370350_0 PhoPQ-activated pathogenicity-related protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 554.0
HFD3_k127_370350_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 550.0
HFD3_k127_3711989_0 Helix-turn-helix domain K15539 - - 0.00000000000004303 83.0
HFD3_k127_3711989_1 BMC K04027 - - 0.0000000000001598 71.0
HFD3_k127_3711989_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006563,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009069,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019752,GO:0019842,GO:0020012,GO:0030170,GO:0030312,GO:0030682,GO:0036094,GO:0042133,GO:0042783,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044464,GO:0046983,GO:0048037,GO:0050662,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0071944,GO:0075136,GO:0097159,GO:1901363,GO:1901564,GO:1901605 2.1.2.1 0.00000001832 56.0
HFD3_k127_3716793_0 amine dehydrogenase activity - - - 0.0000000000005156 83.0
HFD3_k127_3718032_0 AAA ATPase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000173 279.0
HFD3_k127_3718032_1 DNA-templated transcription, initiation K02405 - - 0.0000000000000000000000000000000000000002075 153.0
HFD3_k127_3718400_0 Glycosyl-hydrolase 97 N-terminal K01187 - 3.2.1.20 5.253e-257 808.0
HFD3_k127_3718400_1 Pkd domain containing protein K07407 - 3.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 328.0
HFD3_k127_372553_0 Peptidoglycan-binding domain 1 protein - - - 0.00000000000000000000000000000000000000000000000001518 185.0
HFD3_k127_372553_1 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.00000000000000000000000000000007464 132.0
HFD3_k127_372553_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000003952 98.0
HFD3_k127_3728583_0 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 392.0
HFD3_k127_3728583_1 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000004374 182.0
HFD3_k127_3728583_2 Penicillin amidase K01434 - 3.5.1.11 0.00000000000000000000000000000000000000000005648 160.0
HFD3_k127_3728583_3 Belongs to the amidase family K01426 - 3.5.1.4 0.00000000000001212 78.0
HFD3_k127_3730043_0 Site-specific DNA-methyltransferase (adenine-specific) K06223 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009729 331.0
HFD3_k127_3730640_0 Beta-L-arabinofuranosidase, GH127 K09955 - - 2.364e-248 784.0
HFD3_k127_3730640_1 - - - - 3.928e-226 711.0
HFD3_k127_3734579_0 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000004283 156.0
HFD3_k127_3734579_1 integral membrane protein K07027 - - 0.000000000007934 77.0
HFD3_k127_3738011_0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000003342 151.0
HFD3_k127_3738011_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000211 61.0
HFD3_k127_3738011_2 protein phosphatase 2C domain protein - - - 0.000009528 58.0
HFD3_k127_3743281_0 Peptidase family C25 - - - 0.0000000000000000000000000000000000000000000000000000000004424 224.0
HFD3_k127_3743281_1 PRMT5 oligomerisation domain K11434 - 2.1.1.319 0.000000000000000000000005569 113.0
HFD3_k127_3743281_2 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0000000000000001945 85.0
HFD3_k127_3753225_0 RNA polymerase sigma-54 factor K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 391.0
HFD3_k127_3753225_1 PFAM ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004806 312.0
HFD3_k127_3753225_2 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000004294 112.0
HFD3_k127_3755252_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 426.0
HFD3_k127_3755252_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001773 235.0
HFD3_k127_3755252_2 domain, Protein K07277,K07278,K21449 - - 0.000005709 57.0
HFD3_k127_3757427_0 PFAM Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000001185 240.0
HFD3_k127_3757427_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000002275 64.0
HFD3_k127_3757427_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.000000003417 59.0
HFD3_k127_3757427_3 Belongs to the RtcB family K14415 - 6.5.1.3 0.0000001062 57.0
HFD3_k127_3757427_4 tRNA-splicing ligase RtcB K14415,K18148 - 6.5.1.3 0.000001533 53.0
HFD3_k127_3768288_0 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000507 463.0
HFD3_k127_3768288_1 PFAM ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005011 283.0
HFD3_k127_3769352_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004074 503.0
HFD3_k127_3769352_1 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006635 443.0
HFD3_k127_3769352_2 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006389 256.0
HFD3_k127_3769352_3 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000009202 237.0
HFD3_k127_3769352_4 Putative esterase - - - 0.000000000000000000000000000000000000000000000000001017 196.0
HFD3_k127_3769352_5 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000001664 174.0
HFD3_k127_3769352_6 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000002493 155.0
HFD3_k127_3769352_7 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.0000000696 59.0
HFD3_k127_3769352_8 Tetratricopeptide repeat - - - 0.0003383 53.0
HFD3_k127_3781388_0 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004529 292.0
HFD3_k127_3781388_1 - - - - 0.000000000000000000000000000000000000000000000002286 179.0
HFD3_k127_378641_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 2.067e-269 841.0
HFD3_k127_378641_1 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.00000000000000000000000000138 115.0
HFD3_k127_378641_2 protocatechuate 3,4-dioxygenase activity K03381 - 1.13.11.1 0.000000000000000002992 93.0
HFD3_k127_378641_3 Adenylate cyclase K01768 - 4.6.1.1 0.00000000005945 75.0
HFD3_k127_378641_4 Dienelactone hydrolase family - - - 0.0000001935 64.0
HFD3_k127_3791120_0 AcrB/AcrD/AcrF family K03296 - - 6.775e-318 994.0
HFD3_k127_3791120_1 AcrB/AcrD/AcrF family K03296 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 361.0
HFD3_k127_3797963_0 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000142 253.0
HFD3_k127_38051_0 Aldehyde dehydrogenase family K13877 - 1.2.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009471 367.0
HFD3_k127_38051_1 glycoside hydrolase family 2, TIM barrel K01192 - 3.2.1.25 0.00000000000000000000000000000000000000000000001304 196.0
HFD3_k127_3815659_1 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000007915 76.0
HFD3_k127_382844_0 Tetratricopeptide repeat - - - 0.000000004349 67.0
HFD3_k127_3833433_0 Cation efflux family K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003885 277.0
HFD3_k127_3833433_1 peptidoglycan biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000274 229.0
HFD3_k127_3833433_2 PFAM peptidylprolyl isomerase FKBP-type K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000003098 203.0
HFD3_k127_3833433_3 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000001179 183.0
HFD3_k127_3833433_4 SnoaL-like domain - - - 0.000000000000000000000001878 108.0
HFD3_k127_3844110_0 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 469.0
HFD3_k127_3844110_1 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.0000000000000000000000000000000000000000000000000000000003671 208.0
HFD3_k127_3844110_2 - - - - 0.00000000000000000000000000000000000000000000388 179.0
HFD3_k127_3846611_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 478.0
HFD3_k127_3846611_1 Peptidase, M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000001084 216.0
HFD3_k127_3846611_2 Domain of unknown function (DUF4142) K08995 - - 0.0000000000000000000000000000000000000157 153.0
HFD3_k127_3846611_3 - - - - 0.000000000000000000000000006074 112.0
HFD3_k127_3851470_0 Belongs to the ABC transporter superfamily K02010,K10112 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000904 374.0
HFD3_k127_3851470_1 glycerophosphodiester transmembrane transport K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005557 321.0
HFD3_k127_3851470_2 transmembrane transport K02025,K15771 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002061 283.0
HFD3_k127_3851470_3 Xylose isomerase-like TIM barrel K06606 - 5.3.99.11 0.000000000000000000000000000000000000000000000000000000000000008844 225.0
HFD3_k127_3851470_4 Sulfatase - - - 0.0000001862 54.0
HFD3_k127_3862820_0 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 533.0
HFD3_k127_3862820_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000001086 221.0
HFD3_k127_386881_0 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000002538 233.0
HFD3_k127_386881_1 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.000000000000000000000000001051 115.0
HFD3_k127_3873798_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 7.014e-213 692.0
HFD3_k127_3873798_1 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 325.0
HFD3_k127_3882755_0 Di-haem oxidoreductase, putative peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004288 307.0
HFD3_k127_3882755_1 Predicted membrane protein (DUF2238) K08984 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008355 263.0
HFD3_k127_3882755_2 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000002162 214.0
HFD3_k127_3882755_3 PFAM penicillin-binding protein transpeptidase K05364 - - 0.000000000000000000000000000000000000000000000001181 195.0
HFD3_k127_3882755_4 Belongs to the SEDS family K03588 GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136 - 0.0000000000000000000000000000000000004144 159.0
HFD3_k127_3882755_5 von Willebrand factor, type A K07114 - - 0.0000000005698 70.0
HFD3_k127_3882755_6 Forkhead associated domain - - - 0.00000001721 65.0
HFD3_k127_3886210_0 3-beta hydroxysteroid dehydrogenase isomerase K00091 - 1.1.1.219 0.00000000000000000001717 98.0
HFD3_k127_3886210_1 Belongs to the glycosyl hydrolase 30 family K01201 - 3.2.1.45 0.0000000007299 72.0
HFD3_k127_3886726_0 DNA alkylation repair - - - 0.000000000000000000001102 96.0
HFD3_k127_3886748_0 PFAM NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008275 584.0
HFD3_k127_3888742_0 efflux transmembrane transporter activity K02004 - - 2.37e-226 726.0
HFD3_k127_3888742_1 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 618.0
HFD3_k127_3888742_2 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 555.0
HFD3_k127_3888742_3 YceI-like domain - - - 0.000000000000000000000000000005557 126.0
HFD3_k127_3888742_4 MacB-like periplasmic core domain - - - 0.000000000000000007569 83.0
HFD3_k127_3888742_5 efflux transmembrane transporter activity K02004 - - 0.0000000000000596 72.0
HFD3_k127_3891098_0 PFAM Glycosyl transferase family 2 K00786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005314 457.0
HFD3_k127_3891098_1 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007833 408.0
HFD3_k127_3891098_2 Peptidase M16 inactive domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001146 280.0
HFD3_k127_3891098_3 Peptidase M16 - - - 0.000000000000000000000000000000000000000000000000000000000000000009491 231.0
HFD3_k127_3891098_4 PFAM Peptidase M16 inactive domain - - - 0.0000000000000000000000000000000055 136.0
HFD3_k127_3891098_5 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0005343 46.0
HFD3_k127_389241_0 High-affinity nickel-transport protein K08970 - - 0.000000000000000000000000000000000000000000000000000000000000000002373 243.0
HFD3_k127_389241_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000004123 243.0
HFD3_k127_389241_2 Domain of unknown function (DUF4331) - - - 0.0000000000000000000000000000381 131.0
HFD3_k127_3899375_0 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000227 279.0
HFD3_k127_3899375_1 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity K02372,K02535,K13599,K16363 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171 3.5.1.108,4.2.1.59 0.0000000000000000000000000000000000000000000000000002912 189.0
HFD3_k127_3899375_2 Protein of unknown function (DUF1009) K09949 - - 0.0000000000000000114 85.0
HFD3_k127_38995_0 Vault protein inter-alpha-trypsin domain K07114 - - 0.000000000000000000000000000000000000000000000004834 177.0
HFD3_k127_38995_1 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000695 119.0
HFD3_k127_3899622_0 Subtilase family K14645 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 406.0
HFD3_k127_3899622_1 self proteolysis - - - 0.000000000000000000000000000000000000001463 160.0
HFD3_k127_3899696_0 Ferredoxin K00529,K04755,K08952,K08953,K08954,K15765 GO:0005575,GO:0005622,GO:0005623,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0046858 1.18.1.3 0.000000000000000000000000000000000000000001011 170.0
HFD3_k127_3899696_1 Belongs to the UPF0502 family K09915 - - 0.000000000000000000000000000000000000001136 149.0
HFD3_k127_3899696_2 secreted protein - - - 0.00000000000000001284 86.0
HFD3_k127_39027_0 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 403.0
HFD3_k127_39027_1 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007934 283.0
HFD3_k127_39027_2 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000002957 220.0
HFD3_k127_39027_3 cAMP biosynthetic process K00870,K12132 - 2.7.1.37,2.7.11.1 0.0000000000003333 74.0
HFD3_k127_3902940_0 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 552.0
HFD3_k127_3902940_1 Domain of unknown function (DUF4037) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 312.0
HFD3_k127_3905629_0 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 320.0
HFD3_k127_3905629_1 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000000000005609 171.0
HFD3_k127_3905629_2 - - - - 0.000000000000000009357 86.0
HFD3_k127_3905629_3 - - - - 0.000000000002051 69.0
HFD3_k127_3907548_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006767 362.0
HFD3_k127_3907548_1 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 348.0
HFD3_k127_3907548_2 SMART regulatory protein MerR - - - 0.0000000000000000003478 89.0
HFD3_k127_3908974_0 Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 459.0
HFD3_k127_3908974_1 phosphatase activity K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002523 271.0
HFD3_k127_3908974_2 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003666 274.0
HFD3_k127_3908974_4 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000005675 144.0
HFD3_k127_3908974_5 NTP pyrophosphohydrolases including oxidative damage repair enzymes K03574 - 3.6.1.55 0.000001623 52.0
HFD3_k127_3910474_0 ABC transporter transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000113 259.0
HFD3_k127_3910474_1 - - - - 0.0000000000000000000000000000000000000000000000000000000009688 215.0
HFD3_k127_3910474_2 - - - - 0.00000000000000000000000000000000000000000000000000006751 201.0
HFD3_k127_3910474_3 methyltransferase activity - - - 0.000000000000000000000000000000000009091 143.0
HFD3_k127_3910474_4 Cupin 2, conserved barrel domain protein K18991 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009438,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019243,GO:0019249,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046185,GO:0046394,GO:0051596,GO:0061727,GO:0071704,GO:0072330,GO:1901575,GO:1901576,GO:1901615,GO:1901617 - 0.00000000000000000000000008366 111.0
HFD3_k127_391286_0 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003895 452.0
HFD3_k127_391286_1 response regulator - - - 0.0000000000000000000000000000000000000000000000000000002843 201.0
HFD3_k127_3913995_0 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006303 291.0
HFD3_k127_392754_0 PFAM Bile acid sodium symporter K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 487.0
HFD3_k127_392754_1 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004893 319.0
HFD3_k127_392754_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0050896 4.4.1.5 0.00000000000000000000000000000000000000000000000003322 183.0
HFD3_k127_392754_3 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000008428 176.0
HFD3_k127_392754_4 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000000000000000000004183 151.0
HFD3_k127_392754_5 - - - - 0.000000003315 61.0
HFD3_k127_3928744_0 Belongs to the UbiD family K03182 - 4.1.1.98 3.085e-208 658.0
HFD3_k127_3928744_1 CoA binding domain - - - 0.00000000000000000000000000000000000000002501 161.0
HFD3_k127_3945978_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000001576 271.0
HFD3_k127_3945978_1 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000115 226.0
HFD3_k127_3945978_2 Glycosyl transferase 4-like domain K03525 - 2.7.1.33 0.0000000000000000000000000000000000007327 153.0
HFD3_k127_3945978_3 PFAM SMP-30 Gluconolaconase K20952 - - 0.0000000000000000001079 97.0
HFD3_k127_3946917_0 Acyl-CoA dehydrogenase, C-terminal domain K00248,K09478 - 1.3.8.1,1.3.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 575.0
HFD3_k127_3946917_1 esterase lipase K01432 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000000001212 205.0
HFD3_k127_3946917_2 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000002156 188.0
HFD3_k127_3946917_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000006978 165.0
HFD3_k127_3946917_4 - - - - 0.00007137 51.0
HFD3_k127_3949394_0 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007926 361.0
HFD3_k127_3949394_1 cytochrome C family protein - - - 0.000000000000000000000000000000000000000000000000001769 186.0
HFD3_k127_3949831_0 regulator, PATAN and FRGAF domain-containing - - - 0.0000000000000000000000434 113.0
HFD3_k127_3949831_1 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000639 48.0
HFD3_k127_3959364_0 cytochrome p450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 520.0
HFD3_k127_3959364_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000001259 162.0
HFD3_k127_3959364_2 Acetyltransferase (GNAT) family - - - 0.0000000000000000000747 95.0
HFD3_k127_3959777_0 FR47-like protein - - - 0.0000000000000000000000000000000000000002299 154.0
HFD3_k127_3959777_1 - - - - 0.0000000002217 64.0
HFD3_k127_3965501_0 beta-ketoacyl-acyl-carrier-protein synthase III activity K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 327.0
HFD3_k127_3965501_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000004908 170.0
HFD3_k127_3967876_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007584 451.0
HFD3_k127_3967876_1 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000002267 271.0
HFD3_k127_3967876_2 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000001646 126.0
HFD3_k127_3970395_0 Sigma-70 region 2 K03088 - - 0.000000000000000000000000005692 119.0
HFD3_k127_3970395_1 TatD related DNase K03424 - - 0.000000000000000007193 83.0
HFD3_k127_3970395_2 COG3678 P pilus assembly Cpx signaling pathway, periplasmic inhibitor zinc-resistance associated protein K06006 - - 0.00000001568 63.0
HFD3_k127_3970395_3 - - - - 0.0003 49.0
HFD3_k127_3971732_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000895 536.0
HFD3_k127_3972140_0 Alcohol dehydrogenase GroES-like domain K13953,K18382 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 405.0
HFD3_k127_3972140_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000007353 205.0
HFD3_k127_3973175_0 BNR repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005382 396.0
HFD3_k127_3973175_1 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 378.0
HFD3_k127_3974556_0 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 525.0
HFD3_k127_3974556_1 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 316.0
HFD3_k127_3978796_0 DJ-1/PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007659 276.0
HFD3_k127_3978796_1 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003457 270.0
HFD3_k127_3978796_2 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000006072 210.0
HFD3_k127_3978796_3 protocatechuate 3,4-dioxygenase activity K00449 - 1.13.11.3 0.000000000000000000003023 101.0
HFD3_k127_3987814_0 Glutamine amidotransferases class-II K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 359.0
HFD3_k127_3987814_1 Surface antigen variable number - - - 0.0000000000000000000000000000000000000000000005447 183.0
HFD3_k127_3987814_2 peptidylprolyl isomerase K03771 - 5.2.1.8 0.0000006427 59.0
HFD3_k127_3990929_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K17228 - 1.14.14.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 448.0
HFD3_k127_3990929_1 abc-type fe3 -hydroxamate transport system, periplasmic component - - - 0.000000000000000004814 85.0
HFD3_k127_3990929_2 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000001968 84.0
HFD3_k127_3990929_3 ATP-grasp protein-like protein - - - 0.0000184 48.0
HFD3_k127_3999932_0 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 313.0
HFD3_k127_3999932_1 Peptidase family M50 K11749 - - 0.00000000000000000000000000000000000000000000000000000000002114 220.0
HFD3_k127_3999932_2 PFAM peptidase M24 - - - 0.00000000000000000000000000000000000009965 145.0
HFD3_k127_4000072_0 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001056 292.0
HFD3_k127_4000072_1 Protein of unknown function (DUF1440) - - - 0.0000000000007321 74.0
HFD3_k127_4001414_0 benzoate-CoA ligase K04105 - 6.2.1.25,6.2.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004852 391.0
HFD3_k127_4001414_1 Photosynthesis system II assembly factor YCF48 - - - 0.0000000000000000000000000000000000001263 154.0
HFD3_k127_4001414_2 Bacterial regulatory protein, Fis family - - - 0.000000000000000003577 100.0
HFD3_k127_4001414_3 Transposase - - - 0.0000000000000002991 94.0
HFD3_k127_400197_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 379.0
HFD3_k127_400197_1 Zn peptidase - - - 0.000000000000000000000000000000000000000000000000003867 198.0
HFD3_k127_4002703_0 Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000152 174.0
HFD3_k127_4002703_1 PFAM pentapeptide repeat protein - - - 0.000000000001722 79.0
HFD3_k127_4002703_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000003467 63.0
HFD3_k127_4003359_0 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009207 411.0
HFD3_k127_4003359_1 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 304.0
HFD3_k127_4003359_2 KWG Leptospira - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008489 265.0
HFD3_k127_4003359_3 - - - - 0.000000000000000000000000000000000000002072 150.0
HFD3_k127_4003359_4 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00000000000000002592 94.0
HFD3_k127_4003359_5 Sigma-70 region 2 K03088 - - 0.00000004148 62.0
HFD3_k127_4005668_0 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 294.0
HFD3_k127_4005668_1 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000001069 160.0
HFD3_k127_4010593_0 DNA polymerase K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004279 456.0
HFD3_k127_4010593_1 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000000000000000004775 231.0
HFD3_k127_4012277_0 Cell shape determining protein MreB Mrl K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 291.0
HFD3_k127_4012277_1 hyperosmotic response - - - 0.000000002781 68.0
HFD3_k127_4012277_2 Nucleotidyltransferase DNA polymerase involved in DNA repair K03502 - - 0.0000001065 54.0
HFD3_k127_4014797_0 siderophore transport K02014 - - 1.623e-248 784.0
HFD3_k127_4014797_1 Dihydrodipicolinate synthetase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004801 272.0
HFD3_k127_4014797_2 ROK family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004801 259.0
HFD3_k127_4017565_0 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000001895 244.0
HFD3_k127_4017982_0 Cyclomaltodextrinase, N-terminal K21575 - 3.2.1.135 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 606.0
HFD3_k127_4017982_1 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 451.0
HFD3_k127_4024117_0 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 594.0
HFD3_k127_4024117_1 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 308.0
HFD3_k127_4024117_2 - - - - 0.0000000000000000000000000000000000000000000002727 177.0
HFD3_k127_4024586_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 608.0
HFD3_k127_4024586_1 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008715 389.0
HFD3_k127_402518_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001374 236.0
HFD3_k127_402518_1 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.00000000000000000000000003367 109.0
HFD3_k127_402518_2 TIGRFAM Caa(3)-type oxidase, subunit IV K02277 - 1.9.3.1 0.000000000004776 73.0
HFD3_k127_4033878_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 1.794e-209 656.0
HFD3_k127_4033878_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 284.0
HFD3_k127_4036003_0 Cation transport regulator - - - 0.000000000000000000000000000000000000000000000000000000000000003501 221.0
HFD3_k127_4036003_1 TonB-dependent Receptor Plug Domain K02014,K16092 - - 0.0000000000000000000000000000000000000001163 160.0
HFD3_k127_4036003_2 Cytochrome b subunit of formate dehydrogenase-like protein - - - 0.00000004534 63.0
HFD3_k127_4036003_3 Putative peptidoglycan binding domain - - - 0.0000006101 59.0
HFD3_k127_4041748_0 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 319.0
HFD3_k127_4041748_1 DNA methylase K00571,K07319 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000001069 282.0
HFD3_k127_4041748_2 flagellar motor protein K02557 - - 0.0000003243 53.0
HFD3_k127_4042700_0 O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009749 288.0
HFD3_k127_4042700_1 heptosyltransferase II K02843 - - 0.000000000000005659 85.0
HFD3_k127_4042700_2 - - - - 0.00000000000001378 80.0
HFD3_k127_4042700_3 Glycosyl transferase family 2 - - - 0.000000001061 64.0
HFD3_k127_4049402_0 response regulator - - - 0.000000000000000000000000000000000000000000000000000000001003 207.0
HFD3_k127_4049402_1 Two component regulator propeller - - - 0.00000000000000000000000000000000000001203 154.0
HFD3_k127_4049402_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00002989 55.0
HFD3_k127_4050004_0 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 437.0
HFD3_k127_4050004_1 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 323.0
HFD3_k127_4050004_2 MafB19-like deaminase K01485 - 3.5.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000001478 250.0
HFD3_k127_4050004_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000009362 185.0
HFD3_k127_4050115_0 Peptidase S9, prolyl oligopeptidase active site domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 320.0
HFD3_k127_4050115_1 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K02014 - - 0.0000000000000000000000000000000000000000000000004407 187.0
HFD3_k127_4050234_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 319.0
HFD3_k127_4050234_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01751,K01754,K06016,K17989 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008838,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.6,3.5.1.87,4.3.1.15,4.3.1.17,4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006855 279.0
HFD3_k127_4051990_0 Domain of Unknown function (DUF542) K07322 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000314 248.0
HFD3_k127_4051990_1 nitrite transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000004624 237.0
HFD3_k127_4051990_2 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0050896,GO:0055114 1.2.7.1 0.000000000000000000000000000000000005545 138.0
HFD3_k127_4052014_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K13810 - 2.2.1.2,5.3.1.9 9.449e-201 633.0
HFD3_k127_4052014_1 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000001751 130.0
HFD3_k127_406027_0 anion transmembrane transporter activity K02028,K02045,K02049 - 3.6.3.21,3.6.3.25 0.000000000000000000000000000000000000000000000000000000000006123 219.0
HFD3_k127_406027_1 PFAM S23 ribosomal protein - - - 0.000000000000000000000000000000000000000001658 158.0
HFD3_k127_406027_3 COGs COG0600 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.000000000000000000000000000000003191 139.0
HFD3_k127_4062389_0 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007348 489.0
HFD3_k127_4062389_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 318.0
HFD3_k127_4062389_2 histidine kinase HAMP region domain protein K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000449 209.0
HFD3_k127_4062389_3 TIGRFAM TonB K03832 - - 0.000007203 57.0
HFD3_k127_4065613_0 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 368.0
HFD3_k127_4065613_1 Peptidase family C25 - - - 0.0000000000000000000008291 102.0
HFD3_k127_4069226_0 (Rhomboid) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004433 315.0
HFD3_k127_4069226_1 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000001426 167.0
HFD3_k127_4071331_0 carbohydrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007608 583.0
HFD3_k127_4071331_1 aldo keto reductase - - - 0.0000000000000000009363 87.0
HFD3_k127_407461_0 - - - - 0.00000000000000000000000000000000000000000000000002028 190.0
HFD3_k127_407461_1 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000002434 183.0
HFD3_k127_407461_2 - - - - 0.00000000000000000000000000000000000000000000002767 177.0
HFD3_k127_4081621_0 ABC transporter K02003 - - 0.00000000000000000000000000000000000042 141.0
HFD3_k127_4081621_1 PAS domain - - - 0.0000000000000000000000000011 115.0
HFD3_k127_4081621_2 Xanthine and CO dehydrogenases maturation factor XdhC CoxF K07402 - - 0.000000000000000000000009214 105.0
HFD3_k127_4081621_4 Outer membrane lipoprotein-sorting protein - - - 0.00004461 53.0
HFD3_k127_4082530_0 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 379.0
HFD3_k127_4082530_1 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000121 217.0
HFD3_k127_4082671_0 Molybdenum cofactor synthesis domain protein K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 317.0
HFD3_k127_4082671_1 DinB family - - - 0.000000000000000000000000000000000000000000000000000000008675 207.0
HFD3_k127_4082671_2 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000008394 182.0
HFD3_k127_4095389_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005382 325.0
HFD3_k127_4095389_1 EamA-like transporter family - - - 0.0000000000000000000000000000002869 127.0
HFD3_k127_4097362_0 Probable zinc-ribbon domain - - - 0.00000000000000000000000000000000005992 141.0
HFD3_k127_4097362_1 Sigma-70 region 2 K03088 - - 0.00000000000000000709 91.0
HFD3_k127_4097362_2 A disintegrin and metallopeptidase domain 17b K06059 GO:0000079,GO:0001558,GO:0001666,GO:0001708,GO:0001775,GO:0001817,GO:0001819,GO:0001932,GO:0001934,GO:0001936,GO:0001938,GO:0001959,GO:0001961,GO:0002009,GO:0002011,GO:0002237,GO:0002250,GO:0002252,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002460,GO:0002467,GO:0002520,GO:0002521,GO:0002532,GO:0002682,GO:0002684,GO:0002685,GO:0002687,GO:0002688,GO:0002690,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0004252,GO:0005102,GO:0005112,GO:0005126,GO:0005138,GO:0005178,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005886,GO:0005887,GO:0006508,GO:0006509,GO:0006807,GO:0006928,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007154,GO:0007155,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007173,GO:0007176,GO:0007186,GO:0007219,GO:0007220,GO:0007275,GO:0007346,GO:0007399,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008237,GO:0008284,GO:0009605,GO:0009607,GO:0009611,GO:0009617,GO:0009628,GO:0009653,GO:0009888,GO:0009893,GO:0009966,GO:0009967,GO:0009968,GO:0009986,GO:0009987,GO:0010033,GO:0010469,GO:0010562,GO:0010564,GO:0010594,GO:0010595,GO:0010604,GO:0010632,GO:0010634,GO:0010646,GO:0010647,GO:0010648,GO:0010721,GO:0010803,GO:0010819,GO:0010820,GO:0010941,GO:0010975,GO:0010977,GO:0015629,GO:0016020,GO:0016021,GO:0016324,GO:0016477,GO:0016787,GO:0017015,GO:0017171,GO:0019220,GO:0019221,GO:0019222,GO:0019538,GO:0019904,GO:0022008,GO:0022610,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030097,GO:0030098,GO:0030154,GO:0030165,GO:0030183,GO:0030217,GO:0030307,GO:0030334,GO:0030335,GO:0030511,GO:0030512,GO:0031224,GO:0031226,GO:0031293,GO:0031323,GO:0031325,GO:0031344,GO:0031345,GO:0031399,GO:0031401,GO:0031657,GO:0031659,GO:0032101,GO:0032103,GO:0032268,GO:0032270,GO:0032496,GO:0032501,GO:0032502,GO:0032642,GO:0032722,GO:0032879,GO:0033025,GO:0033032,GO:0033077,GO:0033209,GO:0033619,GO:0033627,GO:0033674,GO:0033993,GO:0034097,GO:0034612,GO:0035313,GO:0035624,GO:0035625,GO:0036293,GO:0038127,GO:0040008,GO:0040011,GO:0040012,GO:0040017,GO:0042058,GO:0042060,GO:0042110,GO:0042113,GO:0042127,GO:0042221,GO:0042325,GO:0042327,GO:0042493,GO:0042742,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043085,GO:0043170,GO:0043207,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043408,GO:0043410,GO:0043535,GO:0043536,GO:0043549,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044319,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044877,GO:0045121,GO:0045165,GO:0045177,GO:0045321,GO:0045595,GO:0045596,GO:0045664,GO:0045665,GO:0045737,GO:0045741,GO:0045742,GO:0045787,GO:0045859,GO:0045860,GO:0045927,GO:0045937,GO:0046649,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048536,GO:0048583,GO:0048584,GO:0048585,GO:0048646,GO:0048679,GO:0048699,GO:0048729,GO:0048731,GO:0048856,GO:0048869,GO:0048870,GO:0050678,GO:0050679,GO:0050730,GO:0050731,GO:0050767,GO:0050768,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050830,GO:0050839,GO:0050896,GO:0050920,GO:0050921,GO:0051088,GO:0051093,GO:0051128,GO:0051129,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051247,GO:0051270,GO:0051272,GO:0051338,GO:0051347,GO:0051674,GO:0051704,GO:0051707,GO:0051716,GO:0051726,GO:0051960,GO:0051961,GO:0060255,GO:0060284,GO:0060429,GO:0060548,GO:0060759,GO:0060760,GO:0061097,GO:0061098,GO:0065007,GO:0065008,GO:0065009,GO:0070011,GO:0070372,GO:0070374,GO:0070482,GO:0070570,GO:0070851,GO:0070887,GO:0071310,GO:0071345,GO:0071356,GO:0071402,GO:0071403,GO:0071704,GO:0071900,GO:0071902,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0090092,GO:0090100,GO:0090101,GO:0090287,GO:0090288,GO:0090504,GO:0090505,GO:0098542,GO:0098589,GO:0098590,GO:0098805,GO:0098857,GO:0120035,GO:0140096,GO:0140131,GO:1901184,GO:1901186,GO:1901564,GO:1901623,GO:1901700,GO:1901987,GO:1901990,GO:1902531,GO:1902533,GO:1902806,GO:1903034,GO:1903265,GO:1903844,GO:1903845,GO:1903846,GO:1904029,GO:1904031,GO:1905562,GO:1905564,GO:2000026,GO:2000045,GO:2000106,GO:2000145,GO:2000147,GO:2000273,GO:2000401,GO:2000403,GO:2000404,GO:2000406,GO:2001222 3.4.24.86 0.000391 51.0
HFD3_k127_409775_0 3-demethylubiquinone-9 3-O-methyltransferase activity K00568,K18827 - 2.1.1.222,2.1.1.294,2.1.1.64,2.7.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006279 302.0
HFD3_k127_409775_1 pathogenesis - - - 0.000000001233 70.0
HFD3_k127_409775_2 Domain of unknown function (DUF4129) - - - 0.0000004231 62.0
HFD3_k127_409775_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0004406 49.0
HFD3_k127_409775_4 Penicillin amidase K01434 - 3.5.1.11 0.0007807 45.0
HFD3_k127_41058_0 D-xylose transmembrane transport K10543 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005975,GO:0005996,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0015749,GO:0015750,GO:0015753,GO:0019321,GO:0030246,GO:0030288,GO:0030313,GO:0031975,GO:0034219,GO:0036094,GO:0042597,GO:0042732,GO:0044238,GO:0044281,GO:0044464,GO:0048029,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003667 400.0
HFD3_k127_41058_1 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007411 271.0
HFD3_k127_4109061_0 PFAM Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 560.0
HFD3_k127_4109061_1 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000002517 215.0
HFD3_k127_4109061_2 deoxyhypusine monooxygenase activity - - - 0.0000000000000000007959 95.0
HFD3_k127_4109061_3 TPR repeat-containing protein - - - 0.0002931 54.0
HFD3_k127_4110333_0 PFAM DAHP synthetase I KDSA K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 339.0
HFD3_k127_4110915_0 electron transfer activity K00428 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000579 290.0
HFD3_k127_4110915_1 Carboxyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001321 254.0
HFD3_k127_4110915_2 dehydrogenase complex catalyzes the overall conversion of - - - 0.00000000000000000000000000000004977 138.0
HFD3_k127_4115882_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 394.0
HFD3_k127_4115882_1 Belongs to the CinA family K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.000000000000000000000000000000000000000000004814 168.0
HFD3_k127_4115882_2 Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.000000000000000000000000000003588 126.0
HFD3_k127_4115882_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.000000000000004778 85.0
HFD3_k127_4117894_0 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006469 436.0
HFD3_k127_4117894_1 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 351.0
HFD3_k127_4117894_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002056 243.0
HFD3_k127_4117894_3 LytTr DNA-binding domain K02477 - - 0.00000000000000000000003473 100.0
HFD3_k127_4117934_0 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000005149 225.0
HFD3_k127_4117934_1 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000000000000000825 220.0
HFD3_k127_4117934_2 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.00000000000000000000000000427 113.0
HFD3_k127_4119235_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 499.0
HFD3_k127_4119235_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 389.0
HFD3_k127_4119235_2 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.00000000000000000000000000003805 126.0
HFD3_k127_4121581_0 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 366.0
HFD3_k127_4121581_1 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 309.0
HFD3_k127_4128826_0 Putative lumazine-binding - - - 0.00000000000000000000000000000000000000000000000002709 184.0
HFD3_k127_4128826_1 Putative lumazine-binding - - - 0.000000000000000000000000000000000000000001919 160.0
HFD3_k127_4129875_0 Phospholipase/Carboxylesterase - - - 0.0000000000000000000000000000000000000000000000204 183.0
HFD3_k127_4130037_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 559.0
HFD3_k127_4130037_1 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 432.0
HFD3_k127_4130037_2 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000000000001815 223.0
HFD3_k127_4131504_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 537.0
HFD3_k127_4131504_1 C-terminal domain of CHU protein family - - - 0.00000000000000000000000000000000000000000005188 179.0
HFD3_k127_4131504_2 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.00000004563 66.0
HFD3_k127_4136564_0 domain, Protein - - - 0.000000000000000000000000000002776 140.0
HFD3_k127_4136564_1 Protein of unknown function (DUF4242) - - - 0.0000000000000000000000000001029 119.0
HFD3_k127_4136564_2 Hep Hag repeat protein - - - 0.00003474 57.0
HFD3_k127_4141312_0 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000005 220.0
HFD3_k127_4141312_1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000005231 205.0
HFD3_k127_4141312_2 Alpha/beta hydrolase family K07020 - - 0.00000000000000000000000000000000000000000000000006826 185.0
HFD3_k127_4141394_0 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000002184 138.0
HFD3_k127_4141394_1 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000004655 102.0
HFD3_k127_4142148_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 370.0
HFD3_k127_4142148_1 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000000005639 173.0
HFD3_k127_4143228_0 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 6.376e-203 644.0
HFD3_k127_4143228_1 membrane protein (homolog of Drosophila rhomboid) - - - 0.000000000000000000000000008842 124.0
HFD3_k127_4144301_0 Belongs to the aldehyde dehydrogenase family K00140,K22187 - 1.2.1.18,1.2.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 383.0
HFD3_k127_4144301_1 PFAM pyruvate phosphate dikinase PEP pyruvate-binding - - - 0.00000000000002118 80.0
HFD3_k127_4148425_0 metallopeptidase activity K06212,K06402 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031224,GO:0031226,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 409.0
HFD3_k127_4148425_1 involved in molybdopterin and thiamine biosynthesis family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008856 303.0
HFD3_k127_4148425_2 - - - - 0.0000000000000000000000962 109.0
HFD3_k127_4151608_0 BNR repeat-like domain K05989 - 3.2.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 439.0
HFD3_k127_4151608_1 FtsX-like permease family K02004 - - 0.0000000000000000000001505 104.0
HFD3_k127_4158764_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 617.0
HFD3_k127_4158764_1 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000002274 221.0
HFD3_k127_4158764_2 Hep Hag repeat protein K11904,K21449 - - 0.000000000000000000009086 108.0
HFD3_k127_4158764_3 Hep Hag repeat protein - - - 0.0000000000000004778 93.0
HFD3_k127_4158764_4 Chaperone of endosialidase - - - 0.00000003838 67.0
HFD3_k127_4158764_5 protein secretion K21449 - - 0.00005284 57.0
HFD3_k127_4159587_0 Sortilin, neurotensin receptor 3, - - - 0.0 1091.0
HFD3_k127_4159587_1 tetratricopeptide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 588.0
HFD3_k127_4159587_2 Peptidase family C25 - - - 0.0000000000000000000000000000000000000000000000000000000000000892 236.0
HFD3_k127_4163052_0 Protein containing tetrapyrrole methyltransferase domain and MazG-like K02428,K02499 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000002701 267.0
HFD3_k127_4163052_1 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000002257 131.0
HFD3_k127_4163052_2 protein conserved in cyanobacteria - - - 0.00000001363 59.0
HFD3_k127_4167660_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000004783 182.0
HFD3_k127_4174072_0 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 302.0
HFD3_k127_4174072_1 D12 class N6 adenine-specific DNA methyltransferase K07318 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000006146 242.0
HFD3_k127_4174072_2 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000001079 132.0
HFD3_k127_4178978_0 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002452 274.0
HFD3_k127_4178978_1 Proton-conducting membrane transporter K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000431 258.0
HFD3_k127_4180238_0 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 382.0
HFD3_k127_4180238_1 lipid kinase, YegS Rv2252 BmrU family - - - 0.0000000000000000000005407 100.0
HFD3_k127_4181327_0 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008659 362.0
HFD3_k127_4181327_1 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000002038 257.0
HFD3_k127_4181327_2 monooxygenase activity - - - 0.000000000000000000000000004052 115.0
HFD3_k127_4190132_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 7.331e-256 807.0
HFD3_k127_4196273_0 two-component system, chemotaxis family, sensor kinase CheA with response regulator domain K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 377.0
HFD3_k127_4196273_1 CheB methylesterase K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 303.0
HFD3_k127_4196273_2 CheR methyltransferase, all-alpha domain K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000001366 248.0
HFD3_k127_4196273_3 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660,K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000003024 239.0
HFD3_k127_4196273_4 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000007321 136.0
HFD3_k127_4196273_5 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000001983 113.0
HFD3_k127_4197203_0 Domain of unknown function (DUF4091) - - - 0.00000000000000000000000000000000000000000000000000000000000009297 235.0
HFD3_k127_4197203_1 symporter activity - - - 0.00000000000000000000000000000000000000004613 168.0
HFD3_k127_4200528_0 DNA topological change - - - 1.162e-274 867.0
HFD3_k127_4200528_1 Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007429 285.0
HFD3_k127_4202640_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000002115 252.0
HFD3_k127_4202640_1 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.0000000000000000000000000000000003381 136.0
HFD3_k127_4204244_0 cAMP biosynthetic process K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 456.0
HFD3_k127_4204244_1 serine-type peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005021 358.0
HFD3_k127_4204244_2 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006008 294.0
HFD3_k127_4204482_0 Tricorn protease PDZ domain K08676 - - 2.808e-205 651.0
HFD3_k127_4204482_1 ABC-2 family transporter protein - - - 0.000000000000000000000000000000000000000002079 165.0
HFD3_k127_4204482_2 Bacitracin ABC transporter ATP-binding protein K20459 - - 0.00005153 47.0
HFD3_k127_4205637_0 histone H2A K63-linked ubiquitination K00998,K06131 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000006868 267.0
HFD3_k127_4205637_1 Protein of unknown function (DUF2752) - - - 0.00000006083 61.0
HFD3_k127_4205637_2 Serine aminopeptidase, S33 - - - 0.000007097 54.0
HFD3_k127_4212726_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000006734 213.0
HFD3_k127_4212907_0 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008524 391.0
HFD3_k127_4212907_1 deoxyhypusine monooxygenase activity K01256,K01387 - 3.4.11.2,3.4.24.3 0.000000000000000000000000000000000002503 152.0
HFD3_k127_4220324_0 TPR repeat - - - 0.0000000006211 71.0
HFD3_k127_4224634_0 Putative glutamine amidotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009301 332.0
HFD3_k127_4229122_0 Caspase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005992 453.0
HFD3_k127_4231233_0 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000001308 178.0
HFD3_k127_4231233_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000006583 92.0
HFD3_k127_4231233_2 Putative zinc-finger - GO:0005575,GO:0016020 - 0.00003759 52.0
HFD3_k127_4232341_0 RmlD substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 410.0
HFD3_k127_4232341_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000006071 237.0
HFD3_k127_4234_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000001872 162.0
HFD3_k127_4234_1 Glycosyl transferases group 1 - - - 0.0000000000000000002151 101.0
HFD3_k127_4234_2 TIGRFAM TonB K03832 - - 0.00000000000000009274 93.0
HFD3_k127_4237743_0 Acyl dehydratase - - - 0.0000000000000000000000000000000000000000005865 160.0
HFD3_k127_4237743_1 dehydratase - - - 0.000000000000000000000006339 106.0
HFD3_k127_4237743_2 VanZ like family - - - 0.00000000000000000001301 96.0
HFD3_k127_4240542_0 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004485 448.0
HFD3_k127_4240542_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 381.0
HFD3_k127_4243583_0 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002803 278.0
HFD3_k127_4243583_1 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104,K03325,K03741,K03892,K18701 - 1.20.4.1,2.8.4.2,3.1.3.48 0.0000000000000000000000005259 111.0
HFD3_k127_4243583_2 Pyruvate phosphate dikinase - - - 0.0000000000000000006748 93.0
HFD3_k127_4243583_3 Pyruvate phosphate dikinase - - - 0.00000000000000009005 81.0
HFD3_k127_4245085_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1011.0
HFD3_k127_4245085_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 8.261e-204 651.0
HFD3_k127_4245085_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000002559 101.0
HFD3_k127_424897_0 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000000000003013 220.0
HFD3_k127_424947_0 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 438.0
HFD3_k127_424947_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000004909 224.0
HFD3_k127_424947_2 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000005218 155.0
HFD3_k127_424947_3 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.000000000002971 72.0
HFD3_k127_424947_4 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.00001654 53.0
HFD3_k127_4251211_0 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006192 498.0
HFD3_k127_4251628_0 Alkyl sulfatase dimerisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 308.0
HFD3_k127_4251628_1 BtpA family K06971 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001616 281.0
HFD3_k127_4253127_0 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004678 265.0
HFD3_k127_4253127_1 Oligopeptide/dipeptide transporter, C-terminal region K02031,K15583 - - 0.000000000000000000003918 94.0
HFD3_k127_4253947_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 8.756e-240 752.0
HFD3_k127_4253947_1 DinB superfamily - - - 0.000002823 52.0
HFD3_k127_4264270_0 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 344.0
HFD3_k127_4264270_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 284.0
HFD3_k127_4264270_2 Methyltransferase domain K00598 - 2.1.1.144 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 285.0
HFD3_k127_4264270_3 Hep Hag repeat protein K11904,K21449 - - 0.00000000000000000006149 97.0
HFD3_k127_4264270_4 Frataxin-like domain K06202 - - 0.0000000000000000001323 93.0
HFD3_k127_4264270_5 Protein of unknown function (DUF1460) - - - 0.0000000000000000005947 91.0
HFD3_k127_4264843_0 stress-induced mitochondrial fusion - - - 0.00000000000000000000000000000000000000000000000000000000000009671 222.0
HFD3_k127_4266625_0 - - - - 0.00000000000000000000000000001664 132.0
HFD3_k127_4266625_1 diguanylate cyclase - - - 0.0000000000000000000006792 97.0
HFD3_k127_4266625_2 Acetyltransferase (GNAT) family - - - 0.00000000000001398 76.0
HFD3_k127_4277847_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 548.0
HFD3_k127_4277847_1 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000008264 230.0
HFD3_k127_4277847_2 SNARE associated Golgi protein - - - 0.00000000000000000000000008702 114.0
HFD3_k127_4277847_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00006577 52.0
HFD3_k127_4282903_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 597.0
HFD3_k127_4282903_1 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005314 254.0
HFD3_k127_4290331_0 Subtilase family - - - 0.0000000000000000000000000006137 122.0
HFD3_k127_4290331_1 Domain of unknown function (DUF4081) K06976 - - 0.00000000000000000000001468 111.0
HFD3_k127_4299714_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004501 507.0
HFD3_k127_4302270_0 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 497.0
HFD3_k127_4302270_1 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 378.0
HFD3_k127_4302270_2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K21310 - 2.1.1.334 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 334.0
HFD3_k127_4302270_3 Protein of unknown function (DUF3455) - - - 0.000000000000000000001207 102.0
HFD3_k127_4302270_4 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - - 0.0001766 51.0
HFD3_k127_4307303_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 462.0
HFD3_k127_4307303_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 325.0
HFD3_k127_4307303_2 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000005503 187.0
HFD3_k127_4307672_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 414.0
HFD3_k127_4307672_1 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 298.0
HFD3_k127_4307672_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000197 232.0
HFD3_k127_4307672_3 diguanylate cyclase - - - 0.00000000000008403 83.0
HFD3_k127_4314675_0 - - - - 0.0000001568 54.0
HFD3_k127_4314675_1 Protein of unknown function (DUF3828) - - - 0.000007034 55.0
HFD3_k127_4314675_2 Beta-lactamase - - - 0.0005155 46.0
HFD3_k127_4330374_0 Heavy-metal-associated domain K17686 GO:0000041,GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0008150,GO:0015677,GO:0016020,GO:0030001,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0051179,GO:0051234,GO:0071944 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003661 268.0
HFD3_k127_4330374_1 ThiJ PfpI - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005752 250.0
HFD3_k127_4330374_2 Cupredoxin-like domain - - - 0.000000000000000000000000000000000000000007039 157.0
HFD3_k127_4330374_3 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0000000000000000000000000000004543 126.0
HFD3_k127_433353_0 phosphate-selective porin O and P K07221 - - 0.00000000000000000000000000000000000000000000000000000000000000006161 241.0
HFD3_k127_433353_1 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000003689 190.0
HFD3_k127_4341739_0 Acts as a magnesium transporter K03281,K04767,K06213,K15986 GO:0000287,GO:0003674,GO:0005488,GO:0005515,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015693,GO:0030001,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0051179,GO:0051234,GO:0070838,GO:0072511 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 324.0
HFD3_k127_4341739_1 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814,K05365 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000004176 162.0
HFD3_k127_4341778_0 Aminopeptidase I zinc metalloprotease (M18) K01267 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008270,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006877 430.0
HFD3_k127_4341778_1 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 410.0
HFD3_k127_4341778_2 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) K07259 - 3.4.16.4 0.0000000004093 63.0
HFD3_k127_4358182_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 3.766e-205 647.0
HFD3_k127_4358182_1 thiolester hydrolase activity K07000 - - 0.0000000000000000000000000000000000000000000000000004413 194.0
HFD3_k127_4358182_2 Protein of unknown function (DUF1569) - - - 0.000000000000000000000000000000000005021 142.0
HFD3_k127_436006_0 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000004475 198.0
HFD3_k127_436006_1 helix_turn_helix, arabinose operon control protein - - - 0.00003926 48.0
HFD3_k127_436360_0 - - - - 0.00000375 55.0
HFD3_k127_4365864_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 336.0
HFD3_k127_4365864_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 324.0
HFD3_k127_4365864_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000002817 86.0
HFD3_k127_4366965_0 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 415.0
HFD3_k127_4366965_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 407.0
HFD3_k127_4366965_2 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 394.0
HFD3_k127_4366965_3 protein conserved in cyanobacteria - - - 0.000000000000000000000000000000000000000000000000000000000004965 213.0
HFD3_k127_4366965_4 Domain of unknown function (DUF4178) - - - 0.000000000000000000000000000000000000006295 149.0
HFD3_k127_4366965_5 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K00797,K01611 - 2.5.1.16,4.1.1.50 0.000000000000000000000000000000000375 136.0
HFD3_k127_4366965_6 Domain of unknown function (DUF4149) - - - 0.00000000000000229 83.0
HFD3_k127_4377331_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001005 293.0
HFD3_k127_4377331_1 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001034 299.0
HFD3_k127_4377331_2 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03404 - 6.6.1.1 0.00001147 49.0
HFD3_k127_4383683_0 Erythromycin esterase - - - 1.197e-205 647.0
HFD3_k127_4383683_1 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000006371 140.0
HFD3_k127_440143_0 Carbamoyltransferase C-terminus K00612 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000543 439.0
HFD3_k127_440143_1 PFAM NAD dependent epimerase dehydratase family K01784,K08678 - 4.1.1.35,5.1.3.2 0.0000000000000000000000000000000000914 136.0
HFD3_k127_440143_2 glycosyl transferase group 1 - - - 0.000001445 51.0
HFD3_k127_4403566_0 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001254 309.0
HFD3_k127_4403566_1 acetyltransferase K15520 - 2.3.1.189 0.000000000006074 68.0
HFD3_k127_4404505_0 mRNA capping enzyme, catalytic domain K01971 - 6.5.1.1 0.00000000000000000000000000002342 119.0
HFD3_k127_4404505_1 dna ligase K10747 GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000007985 112.0
HFD3_k127_4414309_1 RQC K03654 - 3.6.4.12 0.000000001946 61.0
HFD3_k127_4414309_2 PFAM CHAD domain containing protein - - - 0.00003576 52.0
HFD3_k127_441985_0 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002107 243.0
HFD3_k127_441985_1 protocatechuate 3,4-dioxygenase beta subunit K00449 - 1.13.11.3 0.0000000000000000000000000000000000000000000000000000000000001352 219.0
HFD3_k127_441985_2 Putative lumazine-binding - - - 0.00000000000000000000000000000000000000000000000000002019 190.0
HFD3_k127_4427658_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 2.214e-292 932.0
HFD3_k127_4427658_1 TIGRFAM PAS sensor protein - - - 0.00000000000000000000000003634 121.0
HFD3_k127_4442862_0 Belongs to the glycosyl hydrolase 2 family - - - 1.145e-295 916.0
HFD3_k127_4442862_1 beta-glucosidase activity K21000 - - 4.095e-208 650.0
HFD3_k127_4442862_2 beta-glucosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000965 412.0
HFD3_k127_4442862_3 - - - - 0.000000000000000004031 88.0
HFD3_k127_4444486_0 Fibronectin type 3 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006205 320.0
HFD3_k127_4444809_0 Exodeoxyribonuclease iii K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007931 314.0
HFD3_k127_4444809_1 COGs COG2026 Cytotoxic translational repressor of toxin-antitoxin stability system K06218 - - 0.000000000000000000001855 95.0
HFD3_k127_4444809_2 Diguanylate cyclase - - - 0.000000000000002187 78.0
HFD3_k127_4445398_0 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 555.0
HFD3_k127_4445398_1 Autotransporter beta-domain - - - 0.00000000000000000000000006756 124.0
HFD3_k127_4446699_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1319.0
HFD3_k127_4446699_1 Copper binding periplasmic protein CusF K07152 - - 0.00000000000000000000000000000000000000000000000000000007721 201.0
HFD3_k127_4449245_1 Peptidoglycan-binding LysM - - - 0.000000007762 66.0
HFD3_k127_4452202_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 9.831e-300 960.0
HFD3_k127_4452202_1 - - - - 0.000001333 49.0
HFD3_k127_4452202_2 response regulator receiver - - - 0.00003749 48.0
HFD3_k127_4452332_0 polygalacturonase activity K01184 - 3.2.1.15 6.038e-203 642.0
HFD3_k127_4452332_1 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 336.0
HFD3_k127_4454524_0 PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000001394 209.0
HFD3_k127_4454524_1 Mo-co oxidoreductase dimerisation domain K00387 - 1.8.3.1 0.0000000000000000000000000000000000000000000000000009858 196.0
HFD3_k127_4454524_2 - - - - 0.00000000000000000000000000000000000000002544 158.0
HFD3_k127_4454524_4 collagen metabolic process K17948 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0016853,GO:0016854,GO:0016857,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 5.1.3.24 0.000001148 60.0
HFD3_k127_4461036_0 NAD(P)-binding Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 507.0
HFD3_k127_4461036_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 401.0
HFD3_k127_4461036_2 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.0000000000000000000000000000000000000000000000004503 183.0
HFD3_k127_4461036_3 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000000009338 171.0
HFD3_k127_4465476_0 LuxR family transcriptional regulator K03424 - - 0.00000000000000000000000000000000000000000000000000000009506 201.0
HFD3_k127_4465476_1 MerR, DNA binding - - - 0.000000000000000000000000000609 119.0
HFD3_k127_4465476_2 - - - - 0.000000000000000001655 91.0
HFD3_k127_4465476_3 SnoaL-like domain - - - 0.00000000000002618 74.0
HFD3_k127_4466990_0 Amidohydrolase family K01468 - 3.5.2.7 0.00000000000000000000000000000000000003398 146.0
HFD3_k127_4466990_1 RDD domain containing protein - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000009306 107.0
HFD3_k127_447245_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000001443 231.0
HFD3_k127_4489725_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000006531 240.0
HFD3_k127_449409_0 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 370.0
HFD3_k127_449409_1 PFAM Glycosyl Hydrolase Family 88 K18581 - 3.2.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 304.0
HFD3_k127_449409_2 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000447 237.0
HFD3_k127_449409_3 PFAM peptidase K16922 - - 0.00000000000000000000000000000000000000000000003748 192.0
HFD3_k127_4496872_0 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 373.0
HFD3_k127_4496872_1 Cyclin-dependent kinase inhibitor 3 (CDKN3) - - - 0.0000000000000000000000000000000000000001153 155.0
HFD3_k127_4497243_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 488.0
HFD3_k127_4497243_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005675 358.0
HFD3_k127_450421_0 Subtilase family - - - 2.664e-209 690.0
HFD3_k127_450421_1 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000003961 239.0
HFD3_k127_450421_2 acylphosphatase activity K01512 - 3.6.1.7 0.00000000000000001191 85.0
HFD3_k127_450421_3 - - - - 0.00000142 52.0
HFD3_k127_450421_4 Carboxypeptidase regulatory-like domain - - - 0.00003323 55.0
HFD3_k127_4507815_0 polysaccharide deacetylase K22278 - 3.5.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 309.0
HFD3_k127_4507815_1 integral membrane protein - - - 0.00000000000009899 80.0
HFD3_k127_4509685_0 Amidohydrolase family K12960,K20810 - 3.5.4.28,3.5.4.31,3.5.4.40 0.00000000000000000000000000000000000000000000000000000000000000000000000001567 262.0
HFD3_k127_4509685_1 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000003928 177.0
HFD3_k127_4509685_2 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.000000000000000000000000000001074 125.0
HFD3_k127_4510281_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009617 469.0
HFD3_k127_4510281_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003132 262.0
HFD3_k127_4510281_2 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000001228 218.0
HFD3_k127_4510281_3 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000002792 193.0
HFD3_k127_4510281_4 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000619 177.0
HFD3_k127_4510281_5 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000006084 142.0
HFD3_k127_4510281_6 Ribosomal protein L17 K02879 - - 0.0000000000000000000000000000000003383 137.0
HFD3_k127_4510281_7 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000007345 72.0
HFD3_k127_4511150_0 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005814 308.0
HFD3_k127_4511150_1 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000003245 222.0
HFD3_k127_4511150_2 - - - - 0.000000000000000000000000000000000000000000000000003949 188.0
HFD3_k127_4511150_3 BlaR1 peptidase M56 - - - 0.0000000000000000000000000006763 128.0
HFD3_k127_4511150_4 TIGRFAM TonB family K03832 - - 0.00000000000000000003676 104.0
HFD3_k127_4516125_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 2.146e-245 769.0
HFD3_k127_4516125_1 Transposase - - - 0.00000000000005178 82.0
HFD3_k127_4520145_0 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 432.0
HFD3_k127_4520145_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 370.0
HFD3_k127_4520145_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000001441 144.0
HFD3_k127_4520145_3 Yip1 domain - - - 0.0000000000861 73.0
HFD3_k127_4521617_0 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000001284 213.0
HFD3_k127_4521617_1 - - - - 0.0005947 49.0
HFD3_k127_4524642_0 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000001281 187.0
HFD3_k127_4524642_1 peptidyl-tyrosine sulfation - - - 0.00000001377 63.0
HFD3_k127_4524642_2 - - - - 0.0000009634 57.0
HFD3_k127_4524642_3 WD40-like Beta Propeller Repeat - - - 0.000003151 58.0
HFD3_k127_4533315_0 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 305.0
HFD3_k127_4533315_1 Protein of unknown function (DUF3616) - - - 0.0000000000000000000005541 113.0
HFD3_k127_4533315_2 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000003864 80.0
HFD3_k127_4533315_3 involved in transcriptional mechanism. thought to regulate the biosynthesis of the mycobacterial cell wall arabinan and resistance to ethambutol (Emb - - - 0.00000000004636 77.0
HFD3_k127_4533315_4 dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0002859 54.0
HFD3_k127_4533315_5 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0009916 48.0
HFD3_k127_4544900_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.066e-255 797.0
HFD3_k127_4544900_1 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 555.0
HFD3_k127_4544900_2 phosphate acetyltransferase K00625 GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 349.0
HFD3_k127_4544900_3 Zinc-binding dehydrogenase K00060 - 1.1.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000009154 265.0
HFD3_k127_4544900_4 regulation of ruffle assembly - - - 0.00000000000000000000000000000000000000000000000000000000001292 214.0
HFD3_k127_4544900_5 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000004214 148.0
HFD3_k127_4544900_6 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000001084 139.0
HFD3_k127_4544900_7 PFAM 3D domain - - - 0.00000000000001598 82.0
HFD3_k127_4544900_8 Anti-sigma-K factor rskA - - - 0.0008695 50.0
HFD3_k127_4550547_0 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007957 372.0
HFD3_k127_4550547_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 288.0
HFD3_k127_4553475_0 Belongs to the TPP enzyme family K01577 - 4.1.1.8 0.0000000000000007482 83.0
HFD3_k127_4553475_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000001563 74.0
HFD3_k127_4557737_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 332.0
HFD3_k127_4557737_1 CheC inhibitor of MCP methylation K03410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001081 253.0
HFD3_k127_4566282_0 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000001099 268.0
HFD3_k127_4566282_1 Cytochrome c554 and c-prime K04013 - - 0.0002032 50.0
HFD3_k127_4576558_0 Elongation factor SelB winged helix 3 K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009746 435.0
HFD3_k127_4576558_1 DolP-mannose mannosyltransferase - GO:0000030,GO:0003674,GO:0003824,GO:0004169,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006486,GO:0006493,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019538,GO:0034645,GO:0035268,GO:0035269,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044464,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.000000001022 71.0
HFD3_k127_4576882_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 7.271e-237 744.0
HFD3_k127_4576882_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 401.0
HFD3_k127_4576882_2 glutamate synthase alpha subunit domain protein K00265 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000001374 120.0
HFD3_k127_4579282_0 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007678 350.0
HFD3_k127_4579282_1 Hep Hag repeat protein K11904,K21449 - - 0.00000000000000004133 95.0
HFD3_k127_4581673_0 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005897 366.0
HFD3_k127_4584169_0 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004639 425.0
HFD3_k127_4584169_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 366.0
HFD3_k127_4584169_2 Cro/C1-type HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000007891 220.0
HFD3_k127_4584169_3 Belongs to the DapB family K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000003479 210.0
HFD3_k127_4584169_4 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000001773 192.0
HFD3_k127_4584169_5 PFAM peptidase K01438 - 3.5.1.16 0.000000000000002162 77.0
HFD3_k127_4585218_0 Two component regulator propeller - - - 0.00000000000000000000000007572 118.0
HFD3_k127_4586303_0 Protein of unknown function (DUF3142) - - - 0.000000000000006551 88.0
HFD3_k127_4588967_0 Caspase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008074 494.0
HFD3_k127_4588967_1 CHAT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000248 304.0
HFD3_k127_4588967_2 CHAT domain - - - 0.00000000000000000000001289 109.0
HFD3_k127_459664_0 tRNA nucleotidyltransferase poly(A) polymerase K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000009371 211.0
HFD3_k127_459664_1 - - - - 0.0000000182 67.0
HFD3_k127_4597080_0 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring - - - 0.00000000000000000000000000000000000000000000000000000001687 206.0
HFD3_k127_4597080_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000009704 193.0
HFD3_k127_4600779_0 dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000002238 215.0
HFD3_k127_4600779_1 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000007672 94.0
HFD3_k127_4600779_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000001138 72.0
HFD3_k127_4600779_3 PFAM peptidase S1 and S6 chymotrypsin Hap - - - 0.000000009437 68.0
HFD3_k127_4600779_4 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.00002735 50.0
HFD3_k127_4600779_5 Putative zinc-finger - - - 0.0007687 49.0
HFD3_k127_4603861_0 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000004976 240.0
HFD3_k127_4606430_0 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008270,GO:0008534,GO:0009987,GO:0016787,GO:0016788,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006993 286.0
HFD3_k127_4606430_1 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000003915 205.0
HFD3_k127_4606430_2 isoform II - - - 0.0000000000000000000001864 104.0
HFD3_k127_4606430_3 NUDIX domain K03575 - - 0.000000006902 59.0
HFD3_k127_4609002_0 TipAS antibiotic-recognition domain - - - 0.00000000000000000000000000000000000000000000000000000000004049 212.0
HFD3_k127_4615092_0 Carbon starvation protein K06200 - - 1.43e-218 694.0
HFD3_k127_4615092_1 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006804 301.0
HFD3_k127_4615092_2 IstB-like ATP binding protein K02315 - - 0.000000000000000000000000000000000000000000000000000000001661 207.0
HFD3_k127_4615092_3 PNKP adenylyltransferase domain, ligase domain K01090 - 3.1.3.16 0.0000000000000000000000000000000000000001354 156.0
HFD3_k127_4620602_0 DJ-1/PfpI family - - - 0.000000000000000000000000000000000000000000000000007928 188.0
HFD3_k127_4623556_0 Methyl-accepting chemotaxis protein (MCP) signaling domain K11525 - - 0.000000000003385 79.0
HFD3_k127_4623556_1 His Kinase A (phosphoacceptor) domain - - - 0.00000001963 67.0
HFD3_k127_4628916_0 Sodium:solute symporter family - - - 2.316e-248 779.0
HFD3_k127_4628916_1 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001137 271.0
HFD3_k127_4628916_2 Protein of unknown function (DUF455) - - - 0.0000000000000000000000001733 121.0
HFD3_k127_4634617_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 296.0
HFD3_k127_4634617_1 - - - - 0.0000000000000000000008442 101.0
HFD3_k127_4634617_2 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00007403 48.0
HFD3_k127_4635464_0 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567,K07443 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 2.1.1.63 0.000000000000000000000008872 107.0
HFD3_k127_4635464_1 DinB family - - - 0.00000000000001651 79.0
HFD3_k127_4635464_2 Thioesterase superfamily K02614 - - 0.000004154 53.0
HFD3_k127_4637279_0 PKD domain containing protein K01337,K20276,K21449 - 3.4.21.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 385.0
HFD3_k127_4640287_0 amino acid K03294,K13868 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000127 274.0
HFD3_k127_4640287_1 outer membrane autotransporter barrel domain - - - 0.000000000000000000000000000000000001685 156.0
HFD3_k127_4640287_2 - - - - 0.0000000000000000001349 97.0
HFD3_k127_4640287_3 bacterial-type flagellum-dependent cell motility - - - 0.000000000000004096 89.0
HFD3_k127_4640287_4 Kelch domain-containing protein - - - 0.00000000009876 74.0
HFD3_k127_4640697_0 AMP-binding enzyme K01912 - 6.2.1.30 0.000000000000000000000000000000000000000007367 159.0
HFD3_k127_4640697_1 Transcriptional regulatory protein, C terminal K07776 - - 0.0000000000361 76.0
HFD3_k127_4640780_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004671 499.0
HFD3_k127_4648361_0 PFAM Peptidase M20 K12941 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 561.0
HFD3_k127_4648361_1 Belongs to the MlaE permease family K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000182 249.0
HFD3_k127_4648361_2 PFAM HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000001576 228.0
HFD3_k127_4648361_3 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000002178 187.0
HFD3_k127_4648361_4 N-formylglutamate amidohydrolase - - - 0.0000000000000000000000000008191 119.0
HFD3_k127_4650024_0 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001597 264.0
HFD3_k127_4650024_1 Caspase domain - - - 0.0000000000000000000000000000001432 127.0
HFD3_k127_4653146_0 sulfate adenylyltransferase K00958 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005678 497.0
HFD3_k127_4653146_1 3-demethylubiquinone-9 3-O-methyltransferase activity K00568,K15257 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000002414 142.0
HFD3_k127_4661750_0 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 493.0
HFD3_k127_4661750_1 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 420.0
HFD3_k127_4661750_2 Alanine-glyoxylate amino-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007174 378.0
HFD3_k127_4661750_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 360.0
HFD3_k127_4661750_4 Glutamine amidotransferase class-I K01937 - 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000597 260.0
HFD3_k127_4661750_5 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000003341 224.0
HFD3_k127_4661750_6 Gnat family - - - 0.0000000000000000000000000000000000000000000000003313 181.0
HFD3_k127_4661750_8 Histidine biosynthesis bifunctional protein HisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000001807 172.0
HFD3_k127_4661750_9 Protein of unknown function (DUF2911) - - - 0.000002063 58.0
HFD3_k127_4664765_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.019e-269 856.0
HFD3_k127_4664765_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009745 246.0
HFD3_k127_4664765_2 6-phosphofructokinase activity K00850,K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000001378 117.0
HFD3_k127_466565_0 PFAM response regulator receiver K07657 - - 0.0000000000000000000005841 100.0
HFD3_k127_466565_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000001074 91.0
HFD3_k127_466565_2 - - - - 0.00002388 49.0
HFD3_k127_4681289_0 chitinase K01183 - 3.2.1.14 0.00000000000000000003572 96.0
HFD3_k127_4683927_0 guanyl-nucleotide exchange factor activity K01179,K03929,K09612,K12287,K19701,K19702 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005623,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.2.1.4,3.4.11.10,3.4.11.24,3.4.11.6 0.0000000001418 74.0
HFD3_k127_4684502_0 Glycoside hydrolase family 44 - - - 0.00000000000001655 85.0
HFD3_k127_4684502_1 Chain-length determining protein - - - 0.0001758 50.0
HFD3_k127_4686346_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008844 486.0
HFD3_k127_4686346_1 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000000001452 194.0
HFD3_k127_469219_0 pyrroloquinoline quinone binding K01206,K01218 - 3.2.1.51,3.2.1.78 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 353.0
HFD3_k127_469219_1 Domain of unknown function (DUF4159) - - - 0.0002377 46.0
HFD3_k127_4703953_0 PFAM peptidase - - - 3.201e-220 696.0
HFD3_k127_4703953_1 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000002079 231.0
HFD3_k127_4703953_2 WD40 domain protein beta Propeller - - - 0.000000000000000002094 92.0
HFD3_k127_4704364_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1060.0
HFD3_k127_4704364_1 PhoH-like protein K06217 - - 0.00000000000000000000008514 103.0
HFD3_k127_4704586_0 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 386.0
HFD3_k127_4704586_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000001856 183.0
HFD3_k127_4704586_2 Involved in the anomeric conversion of L-rhamnose K03534 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 5.1.3.32 0.0000000000000000000000000000003771 124.0
HFD3_k127_470460_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1184.0
HFD3_k127_470460_1 Lysin motif K08307 - - 0.000000000000000000000000000000001305 143.0
HFD3_k127_4705069_0 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004926 377.0
HFD3_k127_4705069_1 electron transfer activity K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000249 231.0
HFD3_k127_4708637_0 Molybdopterin oxidoreductase Fe4S4 domain K08357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001508 254.0
HFD3_k127_4708637_1 cell redox homeostasis K16089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003935 247.0
HFD3_k127_4708637_2 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000434 143.0
HFD3_k127_47153_0 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005709 515.0
HFD3_k127_47153_1 Peptidase family S58 K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 474.0
HFD3_k127_47153_2 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 466.0
HFD3_k127_47153_3 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003741 426.0
HFD3_k127_47153_4 NmrA-like family K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 389.0
HFD3_k127_47153_5 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000124 158.0
HFD3_k127_47153_6 - - - - 0.0000000000000000000000000000000000002506 145.0
HFD3_k127_47153_7 Protein of unknown function (DUF433) - - - 0.000000000000000000000000001803 115.0
HFD3_k127_47153_8 Phosphorylase superfamily K01243 - 3.2.2.9 0.0000000000000001112 89.0
HFD3_k127_4717902_0 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 334.0
HFD3_k127_4717902_1 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009176 322.0
HFD3_k127_4717902_2 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002348 285.0
HFD3_k127_4717902_3 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.00000000000000007632 89.0
HFD3_k127_4717902_4 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00001148 48.0
HFD3_k127_4723720_0 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009922 391.0
HFD3_k127_4723720_1 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 359.0
HFD3_k127_4723720_2 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.000000000000000000000000000000000000000000000000001297 186.0
HFD3_k127_4723720_3 thiamine diphosphate biosynthetic process K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.000000000000000000000000000000000000000000000000001618 185.0
HFD3_k127_4723720_4 Thiamine biosynthesis protein ThiS K03154 - - 0.000000000002243 70.0
HFD3_k127_4723720_5 - - - - 0.0000000000044 77.0
HFD3_k127_472752_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000235 274.0
HFD3_k127_472752_1 Modulates RecA activity K03565 - - 0.0000000002982 69.0
HFD3_k127_472752_2 Domain of unknown function (DUF4388) - - - 0.00003455 55.0
HFD3_k127_4735027_0 ATPase activity K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 312.0
HFD3_k127_4735027_1 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000001379 197.0
HFD3_k127_4735027_2 - - - - 0.00000000000000000000000000000000000000004221 171.0
HFD3_k127_4735027_3 Rhomboid family - - - 0.000000000000000000000000000000000001945 142.0
HFD3_k127_4735027_4 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000004522 135.0
HFD3_k127_4736482_0 tyrosine recombinase XerC K03733,K04763 - - 0.0000000000000000000000005084 117.0
HFD3_k127_4736482_1 Belongs to the 'phage' integrase family - - - 0.00000000007568 68.0
HFD3_k127_4749882_0 Peptidase dimerisation domain K01436 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 442.0
HFD3_k127_4749882_1 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000000000000009283 209.0
HFD3_k127_4749882_2 - - - - 0.000000000002017 76.0
HFD3_k127_4749882_3 transcriptional regulator, ArsR family - - - 0.00005114 50.0
HFD3_k127_4751883_0 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007891 437.0
HFD3_k127_4751883_1 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001202 262.0
HFD3_k127_4751883_2 - - - - 0.00000002091 59.0
HFD3_k127_4756322_0 cellulase activity K01183,K01728 - 3.2.1.14,4.2.2.2 0.00000134 55.0
HFD3_k127_4771221_0 Protein of unknown function (DUF1003) - - - 0.00000000000000000000000000000000000000000000001034 179.0
HFD3_k127_4771221_1 CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000001568 115.0
HFD3_k127_4771221_2 alpha/beta hydrolase fold - - - 0.00004522 49.0
HFD3_k127_4774247_0 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006169 414.0
HFD3_k127_4774247_1 Beta-eliminating lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 400.0
HFD3_k127_4774247_2 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006924 350.0
HFD3_k127_4774247_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004004 254.0
HFD3_k127_4774247_4 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007516 256.0
HFD3_k127_4774247_5 DNA-templated transcription, initiation K03088 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0010565,GO:0016020,GO:0019216,GO:0019217,GO:0019222,GO:0030312,GO:0031323,GO:0044464,GO:0050789,GO:0050794,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090 - 0.000000000000000000000000000000000000000000000000007591 186.0
HFD3_k127_4774247_6 6-phosphogluconolactonase activity - - - 0.000000000000000008655 99.0
HFD3_k127_4774247_7 Anti-sigma-K factor RskA - - - 0.000000000000006183 87.0
HFD3_k127_4774247_8 Psort location CytoplasmicMembrane, score - - - 0.0000000000005601 75.0
HFD3_k127_4779443_0 GlcNAc-PI de-N-acetylase K01463 - - 0.0000000000000000000000000000000000000000000000000000000001362 212.0
HFD3_k127_4779443_1 glycosyl transferase group 1 K00754 - - 0.000000000000000000000000000000000000000009118 156.0
HFD3_k127_4784032_0 Collagen triple helix repeat (20 copies) - - - 0.0000001229 64.0
HFD3_k127_4789485_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 614.0
HFD3_k127_4789485_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001438 252.0
HFD3_k127_4789485_2 cAMP biosynthetic process - - - 0.000000000000000000000000000000000000000000000008574 181.0
HFD3_k127_4796771_0 Sulfate permease family K01673,K03321 - 4.2.1.1 1.827e-207 659.0
HFD3_k127_4796771_1 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001516 273.0
HFD3_k127_4796771_2 Belongs to the UPF0502 family K09915 - - 0.00000000000000000000000000000000000000000000000000000000000000000005362 238.0
HFD3_k127_4796771_3 - - - - 0.00000000000000000000000000005136 121.0
HFD3_k127_4801268_0 RDD family - - - 0.0000000000000000000000000000000000000000000002192 177.0
HFD3_k127_4801268_1 - - - - 0.000000000000000000000000000008112 134.0
HFD3_k127_4801268_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000004793 71.0
HFD3_k127_4809280_0 MacB-like periplasmic core domain - - - 8.067e-232 742.0
HFD3_k127_4809280_1 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 437.0
HFD3_k127_4809280_2 Acyl-CoA thioester hydrolase/BAAT N-terminal region K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003732 266.0
HFD3_k127_4809280_3 BlaR1 peptidase M56 - - - 0.00000000000000000000000000009296 119.0
HFD3_k127_4817764_0 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 419.0
HFD3_k127_481829_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000001406 205.0
HFD3_k127_4818856_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 2.15e-203 642.0
HFD3_k127_4823711_0 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 415.0
HFD3_k127_4823932_0 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000001269 269.0
HFD3_k127_4823932_1 Caspase domain - - - 0.000000000000000000002403 109.0
HFD3_k127_4823932_2 Trypsin-like peptidase domain - - - 0.000001783 61.0
HFD3_k127_4824513_0 aromatic amino acid beta-eliminating lyase threonine aldolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 344.0
HFD3_k127_4824513_1 Bacterial sugar transferase K19428 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005365 279.0
HFD3_k127_4824513_2 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000001551 168.0
HFD3_k127_4827372_0 Tricorn protease PDZ domain K08676 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001602 272.0
HFD3_k127_4827372_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006389 267.0
HFD3_k127_4827372_2 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000271 157.0
HFD3_k127_4831957_0 PFAM Ribonuclease BN-like family K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 310.0
HFD3_k127_4835926_0 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000004043 166.0
HFD3_k127_4837279_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002438 252.0
HFD3_k127_4837279_1 - - - - 0.000000000000000000000009214 105.0
HFD3_k127_484081_0 von Willebrand factor, type A K07114 - - 7.426e-198 631.0
HFD3_k127_484081_2 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000005629 188.0
HFD3_k127_484081_3 Sugar transferase K19428 - - 0.000000000000000000000001346 113.0
HFD3_k127_484081_4 von Willebrand factor, type A K07114 - - 0.0000000000000000005994 89.0
HFD3_k127_484081_5 pfam yhs - - - 0.00003149 46.0
HFD3_k127_484081_6 Methionine biosynthesis protein MetW - - - 0.0003683 45.0
HFD3_k127_4843347_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1341.0
HFD3_k127_4851078_0 CarboxypepD_reg-like domain - - - 8.57e-204 670.0
HFD3_k127_4852683_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 359.0
HFD3_k127_4859263_0 NIPSNAP family containing protein - - - 0.000000000000000000000000000000000000000003273 161.0
HFD3_k127_4859263_1 Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene) K09880 - 3.1.3.77 0.00000000000000000000000000000000003865 138.0
HFD3_k127_4859263_2 Alpha/beta hydrolase family - - - 0.0000000000000000000000001038 108.0
HFD3_k127_4859263_3 - - - - 0.000000000004207 72.0
HFD3_k127_4861401_0 Outer membrane efflux protein K15725 - - 0.00000000000000000000000000000000000000000000000003914 190.0
HFD3_k127_4862054_0 Trehalose utilisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 420.0
HFD3_k127_4862054_1 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 400.0
HFD3_k127_4862054_2 Amidohydrolase K07045 - - 0.0009593 44.0
HFD3_k127_4862767_0 Histidine kinase K02480,K07683 - 2.7.13.3 9.662e-229 743.0
HFD3_k127_4862767_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000002811 231.0
HFD3_k127_4862767_2 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000002994 59.0
HFD3_k127_4875916_0 - - - - 0.00000000000000000000000000000000000000000000000000000001885 217.0
HFD3_k127_4875916_1 Bacterial protein of unknown function (DUF937) - - - 0.0000000000000000000000000000000000009373 146.0
HFD3_k127_4877012_0 Iron-binding zinc finger CDGSH type - - - 0.000000000000000000000000000000000000000006825 164.0
HFD3_k127_4877012_1 Lysin motif - - - 0.000000000000000000000000000000000000002175 152.0
HFD3_k127_4884358_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000187 282.0
HFD3_k127_4884358_1 MerR HTH family regulatory protein K13640 - - 0.0000000000000000000000000000001208 129.0
HFD3_k127_4884358_2 Pfam:N_methyl_2 - - - 0.00000000000000000003627 96.0
HFD3_k127_4884358_3 Pfam:N_methyl_2 - - - 0.0000000000000001323 86.0
HFD3_k127_4888723_0 Belongs to the ClpA ClpB family K03695,K03696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007449 334.0
HFD3_k127_4888723_1 Sulfatase-modifying factor enzyme 1 K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007862 306.0
HFD3_k127_4888723_2 MMPL family K07003 - - 0.000000000000000000000000000000000000000000001301 185.0
HFD3_k127_4889395_0 serine-type peptidase activity K01303,K12132 - 2.7.11.1,3.4.19.1 3.992e-248 788.0
HFD3_k127_4891507_0 Transposase mutator type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 316.0
HFD3_k127_4891507_1 - - - - 0.0000000000000000000000000000000000000000000000001134 184.0
HFD3_k127_4891507_2 Transposase DDE domain - - - 0.000000000000000000000005619 106.0
HFD3_k127_4892637_0 introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX K03404 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000002693 242.0
HFD3_k127_4892637_1 Lysin motif K08307 - - 0.00001543 51.0
HFD3_k127_4893409_0 C-terminal, D2-small domain, of ClpB protein K11907 - - 3.422e-319 989.0
HFD3_k127_4893409_1 polysaccharide deacetylase - - - 0.0000000000003004 76.0
HFD3_k127_4895414_0 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008448 260.0
HFD3_k127_4895414_1 Cyclic nucleotide-monophosphate binding domain K10914 - - 0.0000000000000000000000000000000000000000000000000000000286 203.0
HFD3_k127_4898416_0 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004759 262.0
HFD3_k127_4898416_1 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005359 255.0
HFD3_k127_4898416_2 peroxiredoxin activity K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000001478 216.0
HFD3_k127_4898416_3 Belongs to the peptidase S8 family K17734 - - 0.000000000000000000000000000000000000000000000000000007007 206.0
HFD3_k127_4898416_4 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.0000000000000000000000000000000000001497 143.0
HFD3_k127_4899421_0 Sugar (and other) transporter - - - 1.696e-208 659.0
HFD3_k127_4899421_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000009084 196.0
HFD3_k127_4899421_2 - - - - 0.0000000000000000000000000000000000000002386 160.0
HFD3_k127_4900328_0 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007052 321.0
HFD3_k127_4900328_1 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 287.0
HFD3_k127_4900328_2 PKD domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000001184 232.0
HFD3_k127_4900328_3 Matrixin - - - 0.000000001752 72.0
HFD3_k127_4900377_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.0000000000000000000000000000000000000000000000000004042 209.0
HFD3_k127_4902170_0 Carboxypeptidase regulatory-like domain - - - 3.463e-201 642.0
HFD3_k127_490387_0 Vault protein inter-alpha-trypsin domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 377.0
HFD3_k127_490387_1 - K19693 - - 0.00000000000000000000000000000000000000000000000000002633 205.0
HFD3_k127_490387_2 PFAM Transposase K07491 - - 0.000000000000000000000000000006406 124.0
HFD3_k127_4906963_0 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 370.0
HFD3_k127_4906963_1 Belongs to the carbohydrate kinase PfkB family. LacC subfamily K00882 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 2.7.1.56 0.00004913 55.0
HFD3_k127_4919087_0 Belongs to the serpin family K13963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 316.0
HFD3_k127_4919087_1 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000004708 166.0
HFD3_k127_4930690_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000005734 274.0
HFD3_k127_4930690_1 DNA-templated transcription, initiation K02405 - - 0.00000000000000000000000000000006008 128.0
HFD3_k127_4931128_0 CHAT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 353.0
HFD3_k127_4931128_1 Serine protease, subtilase family K08651 - 3.4.21.66 0.00000000000000000000000000000000000000005179 173.0
HFD3_k127_4935068_0 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 558.0
HFD3_k127_4935068_1 Transcriptional regulatory protein, C terminal K07662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 295.0
HFD3_k127_4935068_2 PhoQ Sensor K07640 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000186 228.0
HFD3_k127_4939227_0 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 361.0
HFD3_k127_4939227_1 membrane - - - 0.0000000000000000000000000000000000000000000000000001965 190.0
HFD3_k127_4940627_0 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 392.0
HFD3_k127_4940627_1 Phosphate acyltransferases K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000001367 200.0
HFD3_k127_4940627_2 ribosomal large subunit export from nucleus - - - 0.0000000000000000000000000006112 116.0
HFD3_k127_4941194_0 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667 - 4.1.99.1 2.77e-214 674.0
HFD3_k127_4941194_1 hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000009644 149.0
HFD3_k127_4941194_2 Enoyl-CoA hydratase K07537 - 4.2.1.100 0.00000000000000000000569 94.0
HFD3_k127_4947133_0 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 425.0
HFD3_k127_4947133_1 Peptidase M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007091 366.0
HFD3_k127_4947133_2 NAD-dependent epimerase - - - 0.00000000000000000000001111 103.0
HFD3_k127_4947133_3 Updated (2006) note Literature search identified paper linking product function of Cj1296 Cj1297 Cj1298 to antimicrobial efflux pumps K00662 - 2.3.1.81 0.0000000000000000000001844 113.0
HFD3_k127_4953027_0 Aminoglycoside phosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 379.0
HFD3_k127_4953027_1 PFAM Ornithine cyclodeaminase mu-crystallin K01750,K19244 - 1.4.1.1,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000794 243.0
HFD3_k127_4953027_2 Histidine kinase-like ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000009551 220.0
HFD3_k127_4953027_3 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0001011 44.0
HFD3_k127_4956990_0 COG0657 Esterase lipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002423 274.0
HFD3_k127_4957500_0 Sugar kinase of the NBD HSP70 family, may containing an N-terminal HTH domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006084 340.0
HFD3_k127_4957500_1 Threonine/Serine exporter, ThrE - - - 0.00000000000000000000000000000000000000000000000000001961 194.0
HFD3_k127_4963513_0 TrkA-C domain K10716 - - 0.0000000000000000000000000000006863 127.0
HFD3_k127_4963513_1 PDZ DHR GLGF domain protein - - - 0.00000000000000000000000000001829 131.0
HFD3_k127_4964277_0 - - - - 0.0000000000000000000000000000000000000000000000000008853 202.0
HFD3_k127_4965248_0 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005201 325.0
HFD3_k127_4965248_1 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000003561 222.0
HFD3_k127_4965248_2 Transposase DDE domain - - - 0.0002844 47.0
HFD3_k127_4965499_0 Von Willebrand factor type A K02448 - - 0.0000000000000000000000000000000000001492 145.0
HFD3_k127_4965499_1 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000000000000000000000000003038 152.0
HFD3_k127_4965499_2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000009238 62.0
HFD3_k127_4971822_0 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 313.0
HFD3_k127_4971822_1 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000598 202.0
HFD3_k127_4973090_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 7.077e-195 620.0
HFD3_k127_4973090_1 Domain of Unknown Function (DUF350) - - - 0.0000000000000000258 84.0
HFD3_k127_4973090_2 Mut7-C RNAse domain K00525 - 1.17.4.1 0.0005346 44.0
HFD3_k127_4974730_0 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 408.0
HFD3_k127_4974730_1 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002847 258.0
HFD3_k127_4974730_2 - - - - 0.000000000000000000000000001222 120.0
HFD3_k127_497588_0 sigma factor antagonist activity K04757 - 2.7.11.1 0.0000000000000258 87.0
HFD3_k127_4982058_0 PFAM D-galactarate dehydratase Altronate hydrolase K01685 - 4.2.1.7 1.792e-255 797.0
HFD3_k127_4982058_1 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 373.0
HFD3_k127_4988473_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009573 340.0
HFD3_k127_4988473_1 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.000000000000000000000000000000000000000005591 160.0
HFD3_k127_4988473_2 PFAM Transcription regulator MerR DNA binding K13638 - - 0.000000000000000000000000003221 116.0
HFD3_k127_4992477_0 PFAM UMUC domain protein DNA-repair protein K02346,K03502 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000008522 211.0
HFD3_k127_4992477_1 Belongs to the peptidase S24 family K03503 - - 0.00000000000000000000000000000000002008 141.0
HFD3_k127_4992477_2 COG0433 Predicted ATPase - - - 0.0000000000000000000001482 101.0
HFD3_k127_4996832_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 474.0
HFD3_k127_4996832_1 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.000000000000000000000000003608 115.0
HFD3_k127_4996832_2 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.000000145 54.0
HFD3_k127_4999739_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008148 320.0
HFD3_k127_4999739_1 - - - - 0.0000000000001068 82.0
HFD3_k127_4999739_2 Protein of unknown function DUF84 - - - 0.000000000003032 71.0
HFD3_k127_5003610_0 S-layer domain protein - - - 0.00000000000002316 85.0
HFD3_k127_5003610_1 Carboxypeptidase regulatory-like domain - - - 0.0000000004111 73.0
HFD3_k127_5003610_2 domain protein - - - 0.000000007037 69.0
HFD3_k127_5003610_3 Carboxypeptidase regulatory-like domain - - - 0.000005058 57.0
HFD3_k127_500869_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.924e-197 638.0
HFD3_k127_500869_1 IgA Peptidase M64 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006042 564.0
HFD3_k127_500869_2 cell redox homeostasis K16089 - - 0.00000000000000000000000000000000000000000002748 171.0
HFD3_k127_501115_0 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008229 344.0
HFD3_k127_501115_1 PhoD-like phosphatase K01113 - 3.1.3.1 0.000000000000000000000000000000000000000000000004158 175.0
HFD3_k127_501115_2 Winged helix DNA-binding domain - - - 0.000000000000000003504 85.0
HFD3_k127_5037792_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 7.917e-219 683.0
HFD3_k127_5037792_1 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 330.0
HFD3_k127_5040007_0 Glycosyl transferase family group 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 454.0
HFD3_k127_5040007_1 Polysaccharide pyruvyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007228 384.0
HFD3_k127_5040007_2 methyltransferase - - - 0.0000000000000000000000000000000000000000000709 184.0
HFD3_k127_504346_0 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000003853 188.0
HFD3_k127_504346_1 PFAM Glycosyl transferases group 1 - - - 0.00000117 57.0
HFD3_k127_504346_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0007167 52.0
HFD3_k127_5046525_0 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 484.0
HFD3_k127_5046525_1 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000001669 179.0
HFD3_k127_5047119_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 342.0
HFD3_k127_5047119_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009902 287.0
HFD3_k127_5047119_2 four-way junction helicase activity K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.0000000000000000000000000000000000000000000000969 176.0
HFD3_k127_5047119_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00002349 56.0
HFD3_k127_5047119_4 - - - - 0.0007058 43.0
HFD3_k127_5047517_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006651 401.0
HFD3_k127_5047736_0 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006856 481.0
HFD3_k127_50481_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007956 442.0
HFD3_k127_5048146_0 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 458.0
HFD3_k127_5048146_1 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 297.0
HFD3_k127_5048146_2 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001078 277.0
HFD3_k127_5053512_0 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 520.0
HFD3_k127_5053512_1 Cytochrome c K19713 - 1.8.2.2 0.0001065 50.0
HFD3_k127_5056138_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 508.0
HFD3_k127_5056138_1 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000002024 235.0
HFD3_k127_5056138_2 - - - - 0.000000000000000000000000000000000000000000000000000000002905 210.0
HFD3_k127_5056138_3 Protein conserved in bacteria - - - 0.0000001456 57.0
HFD3_k127_5062217_0 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001852 251.0
HFD3_k127_5062217_1 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000004217 220.0
HFD3_k127_5069985_0 Chain length determinant protein - - - 0.0000000000000000000000000000000005094 147.0
HFD3_k127_5072982_0 Fe-S oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 620.0
HFD3_k127_5072982_1 PFAM Electron transfer flavoprotein domain K03522 - - 0.0000000000000000000000000000000000000000000000000000000000009407 221.0
HFD3_k127_5072982_2 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000003655 197.0
HFD3_k127_5072982_3 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000003037 145.0
HFD3_k127_5075094_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006228 538.0
HFD3_k127_5075094_1 BON domain - - - 0.000000000000000000000000000000000000000000000045 175.0
HFD3_k127_5075094_2 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.000000000000001629 81.0
HFD3_k127_5075094_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000002565 64.0
HFD3_k127_5078_0 - - - - 0.00000000002586 73.0
HFD3_k127_5078_1 Putative adhesin - - - 0.0001031 55.0
HFD3_k127_5085922_0 gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 375.0
HFD3_k127_5085922_1 Adenylate cyclase - - - 0.0000003143 61.0
HFD3_k127_5087905_0 Hep Hag repeat protein - - - 0.00000000000000000002576 108.0
HFD3_k127_5087905_1 domain, Protein - - - 0.0000000000001392 83.0
HFD3_k127_5087905_2 - - - - 0.0009145 52.0
HFD3_k127_5097351_0 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 475.0
HFD3_k127_5101978_0 TIGRFAM tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007055 393.0
HFD3_k127_5101978_1 pyrroloquinoline quinone binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004882 307.0
HFD3_k127_5101978_2 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000001212 199.0
HFD3_k127_5101978_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000001741 179.0
HFD3_k127_5101978_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000003057 172.0
HFD3_k127_5101978_5 Peptidase family M50 - - - 0.000000000000000000000000000000000000001334 156.0
HFD3_k127_5117615_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 585.0
HFD3_k127_5117615_1 acetyltransferase - - - 0.0000000000000000000000000000000000000000000007152 179.0
HFD3_k127_5117615_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0001562 45.0
HFD3_k127_5122499_0 Molybdopterin oxidoreductase Fe4S4 domain K00370 - 1.7.5.1 0.0 1592.0
HFD3_k127_5122499_1 Cytochrome c - - - 0.0000000000000000003604 94.0
HFD3_k127_5125175_0 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007885 420.0
HFD3_k127_5125175_1 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 331.0
HFD3_k127_5125175_2 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004513 314.0
HFD3_k127_5125175_3 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002667 273.0
HFD3_k127_5130198_0 MaoC like domain K14449,K18290 - 4.2.1.148,4.2.1.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 347.0
HFD3_k127_5130198_1 Sodium/calcium exchanger protein K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000002693 236.0
HFD3_k127_5135701_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 340.0
HFD3_k127_5135701_1 thiamine pyrophosphate protein TPP binding domain protein K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 325.0
HFD3_k127_5135701_2 Transcriptional regulator, LysR - - - 0.0000000000000000001944 90.0
HFD3_k127_5146546_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 4.771e-202 644.0
HFD3_k127_5146546_1 peptidase - - - 0.00000000000000000000000000000000121 142.0
HFD3_k127_5146617_0 ISFtu1 transposase K01152 - - - 0.0000000000000000000000207 106.0
HFD3_k127_5146617_1 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.00000000000008396 82.0
HFD3_k127_5146617_2 DDE superfamily endonuclease - - - 0.0000001343 59.0
HFD3_k127_5153410_0 acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000001329 242.0
HFD3_k127_5153410_1 Zn-dependent hydrolase, glyoxylase - - - 0.000000000000000000000000000000000000000000000000000003539 203.0
HFD3_k127_5153544_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000002589 237.0
HFD3_k127_5153544_1 Domain of unknown function (DUF4922) - - - 0.0000000000000000000000000000000003135 138.0
HFD3_k127_5153544_2 - - - - 0.000000000000000000000000001407 117.0
HFD3_k127_5153544_3 Prokaryotic N-terminal methylation motif K02650 - - 0.0000164 55.0
HFD3_k127_5157274_0 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007346 387.0
HFD3_k127_5157274_1 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000003012 258.0
HFD3_k127_5157274_2 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000004483 191.0
HFD3_k127_5157274_3 Psort location CytoplasmicMembrane, score - - - 0.000000000001819 74.0
HFD3_k127_5157274_4 - - - - 0.0007807 45.0
HFD3_k127_5159485_0 Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction - - - 0.000000000000000000000000000000000000000000000000000006562 192.0
HFD3_k127_5159485_1 Transcriptional regulatory protein, C terminal - - - 0.00000000000000006381 86.0
HFD3_k127_5163017_0 serine-type peptidase activity - - - 0.0 1082.0
HFD3_k127_5163017_1 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 379.0
HFD3_k127_5170755_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 7.628e-303 940.0
HFD3_k127_5170755_1 4 iron, 4 sulfur cluster binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003834 518.0
HFD3_k127_5170755_2 Biogenesis protein K09792 - - 0.000000000000000000000000000000000000000000000000000000007073 206.0
HFD3_k127_5170755_3 F420H(2)-dependent quinone reductase - - - 0.00000000000000000000000000000000007449 135.0
HFD3_k127_5188798_0 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000006318 228.0
HFD3_k127_5188798_1 sugar phosphate isomerase involved in capsule formation K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000002 203.0
HFD3_k127_5188798_2 Elongation factor SelB, winged helix K03833 - - 0.000000000000000000000000000001262 130.0
HFD3_k127_5189162_0 Bacillithiol biosynthesis BshC K22136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 339.0
HFD3_k127_5189162_1 Belongs to the DapA family K01714,K22397 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0019520,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0047440,GO:0071704,GO:0072329,GO:1901575 4.1.2.28,4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007227 273.0
HFD3_k127_5189162_2 Cupin 2 conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000001638 184.0
HFD3_k127_5201772_0 FtsX-like permease family - - - 1.508e-199 649.0
HFD3_k127_5203639_0 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 316.0
HFD3_k127_5203639_1 PIN domain - - - 0.000000000000000000000000000000000000124 145.0
HFD3_k127_5211642_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 588.0
HFD3_k127_5211642_1 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 429.0
HFD3_k127_5211642_2 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 349.0
HFD3_k127_5211642_3 - - - - 0.0000000000000000000000000000000000000000000000000000002366 207.0
HFD3_k127_5211642_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000004728 176.0
HFD3_k127_5211642_5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000005968 95.0
HFD3_k127_5211642_6 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000002272 62.0
HFD3_k127_521359_0 Caspase domain - - - 0.00000000000000000000000145 119.0
HFD3_k127_5214676_0 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002019 275.0
HFD3_k127_5214676_1 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000002382 220.0
HFD3_k127_5214676_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000001564 188.0
HFD3_k127_5214676_3 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein - - - 0.00000000000000000000000000000129 139.0
HFD3_k127_5214676_4 Uncharacterized conserved protein (DUF2304) - - - 0.00000000001765 70.0
HFD3_k127_5214676_5 Glycine oxidase ThiO K03149,K03153 - 1.4.3.19,2.8.1.10 0.0000009651 52.0
HFD3_k127_5219432_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 385.0
HFD3_k127_5219432_1 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000056 317.0
HFD3_k127_5219432_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000002375 188.0
HFD3_k127_5219432_3 Putative regulatory protein - - - 0.00000000000000001918 85.0
HFD3_k127_5219432_4 peptidyl-tyrosine sulfation - - - 0.000000000007781 77.0
HFD3_k127_5219432_5 PFAM Tetratricopeptide repeat - - - 0.0003126 51.0
HFD3_k127_5219432_6 - - - - 0.0004311 48.0
HFD3_k127_5220758_0 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 437.0
HFD3_k127_5220758_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 317.0
HFD3_k127_5220758_2 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004211 255.0
HFD3_k127_5220758_3 KAP family P-loop domain - - - 0.00000000000000000000000000000000000000000000000000000005192 214.0
HFD3_k127_5224693_0 Ankyrin repeats (many copies) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 557.0
HFD3_k127_5226441_0 Amidase K01426 - 3.5.1.4 2.1e-206 658.0
HFD3_k127_5226441_1 Peptidase family M1 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005518 326.0
HFD3_k127_5226441_2 Major facilitator Superfamily - - - 0.00000000000000000000000002765 116.0
HFD3_k127_5226441_3 ABC-type transport system, periplasmic component surface lipoprotein K07335 - - 0.000000000000001395 78.0
HFD3_k127_5226682_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008744 292.0
HFD3_k127_5226682_1 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000285 200.0
HFD3_k127_5226682_2 glycoside hydrolase family 81 - - - 0.0001623 49.0
HFD3_k127_523078_0 polysaccharide catabolic process K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 506.0
HFD3_k127_523078_1 Myo-inositol oxygenase K00469 - 1.13.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006488 366.0
HFD3_k127_5231723_0 Pyruvate phosphate dikinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001119 241.0
HFD3_k127_5231723_1 TonB dependent receptor K02014,K16087 - - 0.000000000000000000000000000114 133.0
HFD3_k127_5235649_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000681 217.0
HFD3_k127_5235649_1 - - - - 0.00000000000000000000001279 107.0
HFD3_k127_5235649_2 Alpha/beta hydrolase of unknown function (DUF900) - - - 0.00000000000000000001979 96.0
HFD3_k127_5235649_3 Histidine kinase - - - 0.000000000000000003409 90.0
HFD3_k127_5235792_1 WD domain, G-beta repeat - - - 0.000000000000000000000000000000000000000002145 162.0
HFD3_k127_5235792_2 amine dehydrogenase activity - - - 0.000000000000000000000000001865 127.0
HFD3_k127_5242834_0 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000001511 107.0
HFD3_k127_5251591_0 - - - - 0.0000000000000000000000000000000000000000000000000000006098 202.0
HFD3_k127_5251591_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000004079 154.0
HFD3_k127_5251591_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000003251 96.0
HFD3_k127_5252581_0 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002565 271.0
HFD3_k127_5252581_1 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.0000003934 57.0
HFD3_k127_5254106_0 Carboxypeptidase regulatory-like domain - - - 0.0 1183.0
HFD3_k127_5254106_1 FCD K05799 - - 0.00000000000000000000000000000000000000000000000000000000000000001808 233.0
HFD3_k127_5254106_2 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins - - - 0.000000000000000000000000000000000000000000000000000000005123 201.0
HFD3_k127_5260448_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001185 278.0
HFD3_k127_5260448_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18302 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002657 275.0
HFD3_k127_5267648_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 406.0
HFD3_k127_5267648_1 protein-disulfide reductase activity K04084,K06196 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004164 362.0
HFD3_k127_5267648_2 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 289.0
HFD3_k127_5271232_0 Ankyrin repeats (many copies) - - - 4.089e-197 639.0
HFD3_k127_5271232_2 electron transfer activity - - - 0.00000000000004072 78.0
HFD3_k127_5272259_0 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003415 258.0
HFD3_k127_5272259_1 WD40 domain protein beta Propeller - - - 0.000000000000000000000008432 108.0
HFD3_k127_5272259_2 amine dehydrogenase activity - - - 0.0000002623 60.0
HFD3_k127_527251_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 2.608e-244 761.0
HFD3_k127_527255_0 - - - - 0.000000000000000000000000000000000000000000000000000000000003165 212.0
HFD3_k127_528290_0 - - - - 0.00000008147 61.0
HFD3_k127_5291336_0 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000001784 215.0
HFD3_k127_5291336_1 Hep Hag repeat protein K11904,K21449 - - 0.0000000000000000000004375 112.0
HFD3_k127_5291336_2 Fibronectin type 3 domain - - - 0.0000000002044 71.0
HFD3_k127_5291336_3 Chaperone of endosialidase - - - 0.000002719 61.0
HFD3_k127_529427_0 Domain of unknown function (DUF4139) - - - 0.000000000000000000000000000000000000000000000000000000001764 214.0
HFD3_k127_5295040_0 hydrolase, family 3 K05349 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 456.0
HFD3_k127_5295040_1 PFAM carbohydrate kinase K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 338.0
HFD3_k127_529750_0 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008854 419.0
HFD3_k127_529750_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000008109 261.0
HFD3_k127_529750_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000009469 219.0
HFD3_k127_529750_3 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000001109 113.0
HFD3_k127_529750_4 helix_turn_helix, mercury resistance - - - 0.000000000000000000000126 105.0
HFD3_k127_529750_5 Dehydrogenase K00117 - 1.1.5.2 0.000000000001345 75.0
HFD3_k127_529750_6 Domain of unknown function (DU1801) - - - 0.000000001145 64.0
HFD3_k127_529750_7 hydrolase K01048 - 3.1.1.5 0.00002578 47.0
HFD3_k127_5298540_0 ATPase activity K01990,K09697 - 3.6.3.7 0.0000000000000000000000000000000000000000000000000000000000000002117 228.0
HFD3_k127_5298540_1 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00966,K00973,K00992 GO:0000166,GO:0000270,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006040,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019752,GO:0030203,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044281,GO:0046872,GO:0070569,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.7.13,2.7.7.24,2.7.7.99 0.00000000000000000000000000000000000000000000000000332 195.0
HFD3_k127_5298540_2 peptidoglycan turnover K07102 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 0.0000000000000000000000000000000000000002034 164.0
HFD3_k127_5298540_3 CYTH domain K05873 - 4.6.1.1 0.00000000000000000000002147 107.0
HFD3_k127_530260_0 COGs COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001862 268.0
HFD3_k127_530260_1 peptidyl-tyrosine sulfation - - - 0.00000000000000003413 94.0
HFD3_k127_531077_0 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000623 498.0
HFD3_k127_5315735_0 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 449.0
HFD3_k127_5315735_1 amine dehydrogenase activity K17285 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 309.0
HFD3_k127_5315735_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005226 254.0
HFD3_k127_5315877_0 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006192 277.0
HFD3_k127_5315877_1 von Willebrand factor, type A - - - 0.0000000000000000000004455 105.0
HFD3_k127_5319637_0 Bacterial protein of unknown function (DUF885) - - - 4.618e-217 689.0
HFD3_k127_5319637_1 Organic Anion Transporter Polypeptide (OATP) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006797 462.0
HFD3_k127_5319637_2 - - - - 0.000000000000000000000000000000000000003512 152.0
HFD3_k127_5319637_3 3-oxoacyl- acyl-carrier-protein reductase K00059 - 1.1.1.100 0.00000000000000000002356 100.0
HFD3_k127_5319637_4 Pfam:DUF2029 - - - 0.000000001651 66.0
HFD3_k127_5320754_0 phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005752 603.0
HFD3_k127_5320754_1 - - - - 0.000000000000000000000000000000000000000000000000000001157 205.0
HFD3_k127_5320754_2 Tyrosine phosphatase family - - - 0.0000000000000000000000003485 112.0
HFD3_k127_5320754_3 - - - - 0.000000000000000000001966 102.0
HFD3_k127_5320754_4 BON domain - - - 0.00000000000000002206 90.0
HFD3_k127_5326419_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006934 389.0
HFD3_k127_5326419_1 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 316.0
HFD3_k127_5326419_2 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 0.000000000000002057 77.0
HFD3_k127_5330559_0 Belongs to the mandelate racemase muconate lactonizing enzyme family K01706 - 4.2.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 335.0
HFD3_k127_5330559_1 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 301.0
HFD3_k127_5330559_2 Lipocalin / cytosolic fatty-acid binding protein family K03098 - - 0.0000000000000000000000000000000000000000000000000000000000007375 215.0
HFD3_k127_5337924_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 310.0
HFD3_k127_5337924_1 Multicopper oxidase K22348 - 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000004155 259.0
HFD3_k127_5337924_2 Predicted membrane protein (DUF2318) - - - 0.00000000000000000000000000000000000182 144.0
HFD3_k127_5337940_0 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000001373 230.0
HFD3_k127_533825_0 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 286.0
HFD3_k127_533825_1 converts alpha-aldose to the beta-anomer - - - 0.000000000000000000000000000000000000000000000000000000000000211 221.0
HFD3_k127_5343037_0 Squalene/phytoene synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001599 287.0
HFD3_k127_5343037_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001876 284.0
HFD3_k127_5343037_2 ergosterol biosynthetic process K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000001414 260.0
HFD3_k127_5343037_3 Flavin containing amine oxidoreductase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000545 155.0
HFD3_k127_5343037_4 CarD-like/TRCF domain K07736 - - 0.00000000000000000000000000000000000008225 148.0
HFD3_k127_534657_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 299.0
HFD3_k127_5355659_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 348.0
HFD3_k127_5355659_1 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000001312 120.0
HFD3_k127_5355659_2 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0000004734 52.0
HFD3_k127_5356178_0 hydrolase, family 65, central catalytic K15923 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 400.0
HFD3_k127_5356178_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003998 307.0
HFD3_k127_5362491_0 Calcineurin-like phosphoesterase K14379 - 3.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 386.0
HFD3_k127_5362491_1 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 329.0
HFD3_k127_5362491_2 Histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000005403 243.0
HFD3_k127_5362491_3 PFAM response regulator receiver K02483,K07658,K07668 - - 0.000000000000000000002005 96.0
HFD3_k127_537278_0 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 369.0
HFD3_k127_5373751_0 PFAM carbohydrate kinase K00854 - 2.7.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 380.0
HFD3_k127_5373751_1 Protein of unknown function (DUF1232) - - - 0.000000000000000000000001001 109.0
HFD3_k127_5384109_0 domain, Protein - - - 0.0000000002483 70.0
HFD3_k127_5385676_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004386 423.0
HFD3_k127_5385676_1 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000006059 232.0
HFD3_k127_5385676_2 Membrane - - - 0.0000000000000000000000000000000000000000298 155.0
HFD3_k127_5385676_3 peptidase - - - 0.00000000000000000000000000000000946 132.0
HFD3_k127_5385676_4 - - - - 0.0000000000000000000000000005217 122.0
HFD3_k127_5391992_0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 309.0
HFD3_k127_5391992_1 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000007477 214.0
HFD3_k127_5391992_2 Participates in transcription elongation, termination and antitermination K02601 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000007797 108.0
HFD3_k127_5391992_3 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000002243 74.0
HFD3_k127_5394891_0 Transporter-associated region K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 346.0
HFD3_k127_5394891_1 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.0000000000000000000002072 101.0
HFD3_k127_5402181_0 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007724 429.0
HFD3_k127_5402181_1 - - - - 0.00000000000000000000000000000000000000000000000000567 185.0
HFD3_k127_5402181_2 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000009426 129.0
HFD3_k127_5402181_3 PFAM Hemerythrin HHE cation binding domain - - - 0.00000000000000000000002307 106.0
HFD3_k127_5402181_4 glucose sorbosone - - - 0.0000001917 56.0
HFD3_k127_5404748_0 AMP-binding enzyme C-terminal domain K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 499.0
HFD3_k127_5404748_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007963 400.0
HFD3_k127_5412087_0 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.000000001473 61.0
HFD3_k127_5416609_0 MacB-like periplasmic core domain - - - 4.184e-219 705.0
HFD3_k127_5416609_1 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 509.0
HFD3_k127_5416609_2 COG0577 ABC-type antimicrobial peptide transport system permease component - - - 0.00000000000000000000000000000000000000000000000000000001686 205.0
HFD3_k127_5428012_0 - - - - 0.00000000000000000000000000000000000009971 149.0
HFD3_k127_5428012_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000002927 120.0
HFD3_k127_5429511_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 575.0
HFD3_k127_5429511_1 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000003176 103.0
HFD3_k127_5430914_0 phosphorelay signal transduction system K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 464.0
HFD3_k127_5430914_1 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000004078 218.0
HFD3_k127_5430914_2 response regulator K02282 - - 0.000000000000000000000000008755 113.0
HFD3_k127_5433768_0 Predicted integral membrane protein (DUF2270) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001705 249.0
HFD3_k127_5433768_1 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000000001432 133.0
HFD3_k127_5434990_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.672e-309 992.0
HFD3_k127_5441208_0 Sulfatase K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 475.0
HFD3_k127_5442130_0 Pfam:Pyridox_oxidase K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000000001297 235.0
HFD3_k127_5442130_1 Phospholipid methyltransferase - - - 0.000000000000000000000000000000153 125.0
HFD3_k127_5442130_2 hydrolase - - - 0.0000002327 52.0
HFD3_k127_5448318_0 Protein export membrane protein K03296,K18138 - - 0.0 1093.0
HFD3_k127_5448318_1 Biotin-lipoyl like K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 383.0
HFD3_k127_5448318_2 Domain of unknown function (DUF1956) - - - 0.0000000000000000000000000459 116.0
HFD3_k127_5460723_0 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 334.0
HFD3_k127_546118_0 PFAM ABC transporter related K06020 - 3.6.3.25 2.939e-289 895.0
HFD3_k127_546118_1 protein kinase activity - - - 0.000000000000000002343 94.0
HFD3_k127_546118_2 Protein of unknown function (DUF1501) - - - 0.000000000003382 69.0
HFD3_k127_5470386_0 Carboxypeptidase regulatory-like domain - - - 1.392e-207 669.0
HFD3_k127_5470386_1 Beta-galactosidase - - - 6.909e-196 626.0
HFD3_k127_548649_0 metal-dependent hydrolase of the TIM-barrel fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005836 424.0
HFD3_k127_548649_1 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005147 361.0
HFD3_k127_548649_2 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000007573 250.0
HFD3_k127_5488782_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 432.0
HFD3_k127_5488782_1 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007781 324.0
HFD3_k127_5488782_2 Chain length determinant protein - - - 0.000006414 57.0
HFD3_k127_5488782_3 -O-antigen K02847 - - 0.0002942 53.0
HFD3_k127_5488782_4 Evidence 4 Homologs of previously reported genes of - - - 0.0004188 49.0
HFD3_k127_5491419_0 domain, Protein - - - 0.00000000000000000000008973 114.0
HFD3_k127_5491419_1 Hep Hag repeat protein K11904,K21449 - - 0.000000000000002222 90.0
HFD3_k127_5491419_2 BNR repeat-like domain - - - 0.0000000002561 66.0
HFD3_k127_549286_0 Family of unknown function (DUF695) - - - 0.000000000000000000000000000000009548 132.0
HFD3_k127_549286_1 PFAM pyridoxamine 5'-phosphate oxidase-related, FMN-binding K07006 - - 0.00000000000000000000000001983 113.0
HFD3_k127_549286_2 Sodium/calcium exchanger protein K07301 - - 0.000000000000000000002944 97.0
HFD3_k127_5502557_0 Caspase domain - - - 0.0000004637 59.0
HFD3_k127_5502557_1 N-acetylmuramoyl-L-alanine amidase - - - 0.000001224 59.0
HFD3_k127_5502557_2 Transposase (IS116 IS110 IS902 family) - - - 0.000005466 49.0
HFD3_k127_5503340_0 lyase activity - - - 0.000000000000000000000000000000000000000000000000000000002238 210.0
HFD3_k127_5503340_1 O-methyltransferase activity K00543,K13169 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008172,GO:0008757,GO:0009058,GO:0009059,GO:0009308,GO:0009309,GO:0009987,GO:0010467,GO:0010817,GO:0016740,GO:0016741,GO:0017096,GO:0017144,GO:0018130,GO:0019438,GO:0019538,GO:0030186,GO:0030187,GO:0032259,GO:0034641,GO:0034645,GO:0034754,GO:0042401,GO:0042430,GO:0042435,GO:0042445,GO:0042446,GO:0042802,GO:0042803,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046483,GO:0046983,GO:0048519,GO:0050789,GO:0050793,GO:0051093,GO:0051239,GO:0051241,GO:0065007,GO:0065008,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1905939,GO:1905940,GO:2000018,GO:2000019,GO:2000026,GO:2000241,GO:2000242 2.1.1.4 0.00000000000000000000000000000005039 133.0
HFD3_k127_5509826_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 393.0
HFD3_k127_5509826_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000008011 109.0
HFD3_k127_5512385_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 362.0
HFD3_k127_5512385_1 PFAM Rhomboid family protein K19225 - 3.4.21.105 0.000000000000000000000000000000003949 143.0
HFD3_k127_5512385_2 AI-2E family transporter - - - 0.0000000000001025 82.0
HFD3_k127_5512385_3 Bacterial regulatory protein, Fis family - - - 0.0000001006 65.0
HFD3_k127_5516376_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05825 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 481.0
HFD3_k127_5516376_1 cytokinin biosynthetic process K06966 - 3.2.2.10 0.000000000000000000000000239 111.0
HFD3_k127_5519168_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 564.0
HFD3_k127_5519168_1 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 336.0
HFD3_k127_5519168_2 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000008781 119.0
HFD3_k127_5519168_3 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000003081 82.0
HFD3_k127_5521506_0 Protein of unknown function (DUF3089) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007426 447.0
HFD3_k127_5521506_1 PBS lyase HEAT-like repeat - - - 0.00000000000000000000000000001715 134.0
HFD3_k127_5521506_2 Alpha beta hydrolase - - - 0.0000000000000000002763 91.0
HFD3_k127_5521506_3 oxidoreductase activity K12511 - - 0.00000001408 61.0
HFD3_k127_5521506_4 - - - - 0.000778 46.0
HFD3_k127_5523388_0 Hep Hag repeat protein K21449 - - 0.000000000000000000000000000000000000000000000000000000000000001153 237.0
HFD3_k127_5523388_1 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000001647 201.0
HFD3_k127_5523388_2 Protein of unknown function (DUF3455) - - - 0.000000000000000000000006548 109.0
HFD3_k127_5528271_0 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000002932 205.0
HFD3_k127_5528271_1 Cytochrome c K08685 - 1.4.9.1 0.0000000000000000000000000001274 124.0
HFD3_k127_5528271_2 SnoaL-like polyketide cyclase - - - 0.0000000000000000000177 96.0
HFD3_k127_5528276_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 456.0
HFD3_k127_5528276_1 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K02003,K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007479 254.0
HFD3_k127_5528276_2 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000005245 212.0
HFD3_k127_5528276_3 FtsX-like permease family - - - 0.000000000000000000000000000000008024 134.0
HFD3_k127_5529915_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007783 418.0
HFD3_k127_5532748_0 acetyl-coa acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 509.0
HFD3_k127_5532748_1 Alpha beta hydrolase K14731 - 3.1.1.83 0.0000000000000000000000000000000000000000000000648 173.0
HFD3_k127_5532748_2 Protein of unknown function (DUF962) - - - 0.0000000000000000000000000000000000000000001111 160.0
HFD3_k127_5532748_3 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.0000000000000000000000000000000000000007548 152.0
HFD3_k127_5532748_4 - - - - 0.000000001873 65.0
HFD3_k127_5535576_0 Carboxypeptidase regulatory-like domain - - - 6.338e-208 672.0
HFD3_k127_554635_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000049 624.0
HFD3_k127_5552358_0 Beta-lactamase K01286 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 489.0
HFD3_k127_5564102_0 - - - - 0.0000000000000000002246 102.0
HFD3_k127_5565155_0 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 336.0
HFD3_k127_5565155_1 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006793 267.0
HFD3_k127_5582178_0 Iron-containing alcohol dehydrogenase K00001,K13954 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009285 402.0
HFD3_k127_5582178_1 protein kinase related protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006194 311.0
HFD3_k127_5582178_2 PQQ-like domain - - - 0.0000000000000000001845 90.0
HFD3_k127_5587529_0 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005581 509.0
HFD3_k127_5594376_0 KR domain K13774 - - 0.0000000000001542 73.0
HFD3_k127_5594376_1 Belongs to the glycosyl hydrolase 13 family K21575 - 3.2.1.135 0.0000000000007249 77.0
HFD3_k127_5594376_2 Transposase IS200 like - - - 0.000000000004507 72.0
HFD3_k127_5606915_0 amine oxidase K00276 - 1.4.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006434 279.0
HFD3_k127_5606915_1 Protein of unknown function (DUF2911) - - - 0.000000000000000006675 91.0
HFD3_k127_5611449_0 GTP-binding protein TypA K06207 - - 3.248e-264 825.0
HFD3_k127_5611449_1 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006379 344.0
HFD3_k127_5612280_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 508.0
HFD3_k127_5615600_0 Removes 5-oxoproline from various penultimate amino acid residues except L-proline K01304 GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 3.4.19.3 0.00000000000000000000000000000000000000000000000000000000000000000005914 237.0
HFD3_k127_5617619_0 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000401 410.0
HFD3_k127_5617619_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000003724 230.0
HFD3_k127_562035_0 peptidase S9B dipeptidylpeptidase IV domain protein K01278 - 3.4.14.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 608.0
HFD3_k127_562035_1 Lamin Tail Domain K07004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 471.0
HFD3_k127_562035_2 Putative porin - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000001957 55.0
HFD3_k127_5622786_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004465 609.0
HFD3_k127_5626074_0 beta-galactosidase activity - - - 1.277e-203 642.0
HFD3_k127_5626074_1 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 432.0
HFD3_k127_5626074_2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain K05989 - 3.2.1.40 0.000000000000000000000000000000000000000000005738 169.0
HFD3_k127_5630985_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 613.0
HFD3_k127_5630985_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007675 345.0
HFD3_k127_5630985_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000001796 255.0
HFD3_k127_5630985_3 methyltransferase - - - 0.00000000000000000000000000000000000000000000000003425 185.0
HFD3_k127_5630985_4 metallopeptidase activity - - - 0.0000000000000000000003409 98.0
HFD3_k127_5633172_0 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000007217 164.0
HFD3_k127_5633172_1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000518 94.0
HFD3_k127_5633172_2 RESPONSE REGULATOR receiver - - - 0.000000000000000002529 89.0
HFD3_k127_5633172_3 Response regulator, receiver K06147 - - 0.000000000000002531 81.0
HFD3_k127_5642259_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009344 438.0
HFD3_k127_5642259_1 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003375 374.0
HFD3_k127_5642259_2 extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 366.0
HFD3_k127_5642259_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009632 297.0
HFD3_k127_5642259_4 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000007613 128.0
HFD3_k127_5642259_5 Phosphotransferase System K11189 - - 0.0000000000000000005994 89.0
HFD3_k127_5643306_0 Belongs to the ompA family - - - 0.00000004825 64.0
HFD3_k127_5643306_1 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000003567 61.0
HFD3_k127_5643306_2 Alpha-amylase domain K01182 - 3.2.1.10 0.000004639 51.0
HFD3_k127_5647425_0 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 371.0
HFD3_k127_5647425_1 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001341 282.0
HFD3_k127_564771_0 PFAM SMP-30 Gluconolaconase K20952 - - 0.00000000000000000000000000000000000000001112 166.0
HFD3_k127_564771_1 Tetratricopeptide repeat - - - 0.000002372 59.0
HFD3_k127_5649144_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 446.0
HFD3_k127_5650792_0 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000002887 236.0
HFD3_k127_5654882_0 Secretion system protein K12276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 506.0
HFD3_k127_5660550_0 tRNA (guanine(37)-N(1))-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 361.0
HFD3_k127_5660550_1 Dehydrogenase K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000006881 217.0
HFD3_k127_5661492_0 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 405.0
HFD3_k127_5661492_1 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003401 270.0
HFD3_k127_5661492_2 Thiamine-binding protein - - - 0.000000000000000000005201 95.0
HFD3_k127_5661492_3 WD domain, G-beta repeat - - - 0.00000000000000001862 89.0
HFD3_k127_5661492_4 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000009462 68.0
HFD3_k127_5665360_0 cellulose binding - - - 0.000000000000004039 89.0
HFD3_k127_5667520_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 1.344e-208 670.0
HFD3_k127_5667520_1 PBS lyase HEAT-like repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004707 344.0
HFD3_k127_5667520_2 Two component signalling adaptor domain K03408 - - 0.0000002931 52.0
HFD3_k127_5667834_0 Belongs to the peptidase S8 family K17734 - - 0.00000000000000000000000000000000000000002625 171.0
HFD3_k127_5667834_1 Bacterial transcriptional activator domain - - - 0.000000000442 71.0
HFD3_k127_5676282_0 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 346.0
HFD3_k127_5676282_1 Putative adhesin K11621 - - 0.000000005474 66.0
HFD3_k127_5676852_0 Aminotransferase class-V K01556 - 3.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 547.0
HFD3_k127_5676852_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009711 534.0
HFD3_k127_5676852_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001956 228.0
HFD3_k127_5689736_0 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 330.0
HFD3_k127_5691703_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 384.0
HFD3_k127_5691703_1 Polysaccharide biosynthesis protein K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 349.0
HFD3_k127_5691703_2 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000002122 199.0
HFD3_k127_5691703_3 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000002251 144.0
HFD3_k127_5691703_4 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000006295 84.0
HFD3_k127_5691703_5 spectrin binding - - - 0.000000000003621 71.0
HFD3_k127_56997_0 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 317.0
HFD3_k127_56997_1 Transporter associated domain - - - 0.000000000000000000000000000000000000000000000000000000000001159 226.0
HFD3_k127_56997_2 7TM-HD extracellular K07037 - - 0.0000000000000000000000000000000000000000000000000000001825 200.0
HFD3_k127_56997_3 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000001968 189.0
HFD3_k127_56997_4 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000005034 102.0
HFD3_k127_5700129_0 Peptidase family M49 - - - 5.873e-201 641.0
HFD3_k127_5700129_1 membrane - - - 0.00000000000000000008629 98.0
HFD3_k127_57087_0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000253 196.0
HFD3_k127_5714223_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000002308 213.0
HFD3_k127_5714223_1 acetyltransferase - - - 0.0000000000000000000001508 104.0
HFD3_k127_5717182_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 477.0
HFD3_k127_5717182_1 surface antigen - - - 0.000000000000003337 91.0
HFD3_k127_5720536_0 Heparinase II/III-like protein K19051 GO:0003674,GO:0003824,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006082,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008201,GO:0009056,GO:0009057,GO:0009987,GO:0016829,GO:0016835,GO:0016837,GO:0030202,GO:0030203,GO:0030211,GO:0042597,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044248,GO:0044273,GO:0044281,GO:0044464,GO:0047488,GO:0071704,GO:0097367,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1901681,GO:1903510 4.2.2.7,4.2.2.8 0.0000000000000000000000000000000000000000000002235 191.0
HFD3_k127_5721662_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305 396.0
HFD3_k127_5721662_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000001637 210.0
HFD3_k127_5721662_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000000002496 198.0
HFD3_k127_5721662_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000001377 166.0
HFD3_k127_5721662_4 binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000001629 143.0
HFD3_k127_5721662_5 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000002352 104.0
HFD3_k127_5721662_6 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000003386 107.0
HFD3_k127_5724371_0 TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005212 403.0
HFD3_k127_5724371_1 SPTR Transposase, IS4 family protein - - - 0.000000000000000002767 95.0
HFD3_k127_5724677_0 Sortilin, neurotensin receptor 3, - - - 4.705e-223 700.0
HFD3_k127_5725970_0 Transcriptional regulator - - - 2.673e-267 832.0
HFD3_k127_5725970_1 Proposed nucleic acid binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000005306 230.0
HFD3_k127_57262_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00334,K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 496.0
HFD3_k127_57262_1 formate dehydrogenase (NAD+) activity K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 340.0
HFD3_k127_57262_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000006752 171.0
HFD3_k127_57262_3 NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000252 160.0
HFD3_k127_5732480_0 efflux transmembrane transporter activity - - - 4.039e-196 640.0
HFD3_k127_5732480_1 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 480.0
HFD3_k127_5732480_2 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 400.0
HFD3_k127_5735412_0 Cytochrome C and Quinol oxidase polypeptide I K00404 - 1.9.3.1 8.9e-260 805.0
HFD3_k127_5735412_1 Cytochrome C oxidase, mono-heme subunit/FixO K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 353.0
HFD3_k127_5735412_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 308.0
HFD3_k127_5738304_0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein - - - 0.0000000000000000000000000000008099 137.0
HFD3_k127_5739739_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000006612 175.0
HFD3_k127_5745540_0 Putative carbohydrate binding domain K12373 - 3.2.1.52 7.421e-220 695.0
HFD3_k127_574576_0 Phosphate acyltransferases K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 480.0
HFD3_k127_574576_1 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000000000000001493 120.0
HFD3_k127_574576_2 Universal stress protein - - - 0.0001395 53.0
HFD3_k127_5752846_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K00256 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 331.0
HFD3_k127_5752846_1 [2Fe-2S] binding domain - - - 0.000000000000000000000000000000000000000000000000000000000001075 213.0
HFD3_k127_575696_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 397.0
HFD3_k127_5758952_0 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005368 377.0
HFD3_k127_5758952_1 Histidine kinase K07675 - 2.7.13.3 0.000000000000000000001682 96.0
HFD3_k127_5758952_2 Psort location Cytoplasmic, score 8.87 K07407 - 3.2.1.22 0.000000000000000007775 96.0
HFD3_k127_5758952_3 helix_turn_helix, Lux Regulon - - - 0.000000000000000144 81.0
HFD3_k127_5758952_4 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.000000000000002593 79.0
HFD3_k127_5763478_0 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000005649 135.0
HFD3_k127_5763478_1 Hfq protein - - - 0.0000000000000000000000000003006 119.0
HFD3_k127_5763478_2 COG3209 Rhs family protein - - - 0.00003749 51.0
HFD3_k127_5764549_0 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000654 259.0
HFD3_k127_5768173_0 Tachylectin - - - 0.000000000000000000000003309 115.0
HFD3_k127_5768173_1 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000005908 117.0
HFD3_k127_5775430_0 with different specificities (related to short-chain alcohol K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 292.0
HFD3_k127_5775430_1 PFAM GCN5-related N-acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000003292 213.0
HFD3_k127_5775430_2 alpha-ribazole phosphatase activity K01834 GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009628,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036293,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.4.2.11 0.00000000000000000000009225 105.0
HFD3_k127_578941_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01707 - 4.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 334.0
HFD3_k127_578941_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006192 277.0
HFD3_k127_578941_2 KR domain K00065 - 1.1.1.127 0.0000000000000000000000000000000000000006014 149.0
HFD3_k127_578941_3 Belongs to the IlvD Edd family K01687,K22186 - 4.2.1.82,4.2.1.9 0.0000000000000000000000000000000103 128.0
HFD3_k127_5791212_0 Acyclic terpene utilisation family protein AtuA - - - 6.601e-201 634.0
HFD3_k127_5791212_1 PFAM Iron sulphur-containing domain, CDGSH-type - - - 0.00000000000000000000672 94.0
HFD3_k127_5791212_2 - - - - 0.000000000000001089 78.0
HFD3_k127_5791212_3 Prolyl oligopeptidase family - - - 0.00004683 51.0
HFD3_k127_5795557_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 442.0
HFD3_k127_5795557_1 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000008394 201.0
HFD3_k127_5795557_2 Ribosomal protein S9/S16 K02996 - - 0.0000000000000000000000000000000000000000000000001078 180.0
HFD3_k127_5795557_3 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000001148 98.0
HFD3_k127_5796461_0 Ftsk_gamma K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006734 610.0
HFD3_k127_5803668_0 Hep Hag repeat protein - - - 0.00000000000000000003604 99.0
HFD3_k127_5803668_1 response regulator - - - 0.000000000000000126 82.0
HFD3_k127_5822_0 - - - - 0.000002155 59.0
HFD3_k127_5823103_0 Protein kinase domain K08884 - 2.7.11.1 0.00000000000000000000000000000000000000000000000001389 198.0
HFD3_k127_5828326_0 SCO1/SenC K07152,K08976 - - 0.000000000000000000000000000000000000000008045 157.0
HFD3_k127_5828326_1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases K03830 - - 0.00000001008 62.0
HFD3_k127_5830525_0 domain protein - - - 0.000000000000002124 90.0
HFD3_k127_5834234_0 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000005379 192.0
HFD3_k127_5834234_1 lactoylglutathione lyase activity K03088 - - 0.000000003963 68.0
HFD3_k127_5834234_2 - - - - 0.00000003045 62.0
HFD3_k127_583720_0 Prolyl oligopeptidase family - - - 1.237e-273 859.0
HFD3_k127_583720_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 469.0
HFD3_k127_583720_2 - - - - 0.00000000000001106 76.0
HFD3_k127_5839560_0 PAP2 superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000005113 226.0
HFD3_k127_5839560_1 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000001818 120.0
HFD3_k127_5842440_0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 2.53e-251 783.0
HFD3_k127_5842440_1 Belongs to the glycosyl hydrolase 28 family - - - 0.0000000000000000003791 90.0
HFD3_k127_5854152_0 Required for morphogenesis under gluconeogenic growth conditions - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 329.0
HFD3_k127_5854152_1 Tetrapyrrole (Corrin/Porphyrin) Methylases K01719,K02302,K02303,K13542 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.00000000000000000000000000000000000000000000000000000218 202.0
HFD3_k127_5854152_2 Tetratricopeptide repeat - - - 0.0000000000005362 79.0
HFD3_k127_5854152_3 Beta-lactamase - - - 0.000000000004877 66.0
HFD3_k127_5854152_4 membrane - - - 0.0000006421 59.0
HFD3_k127_5864292_0 Protein of unknown function (DUF1009) K09949 - - 0.000000000000000000000000000000000000000000000000000000000000131 218.0
HFD3_k127_5864292_1 Outer membrane protein (OmpH-like) K06142 - - 0.000000003428 66.0
HFD3_k127_5864292_2 outer membrane chaperone Skp (OmpH) K06142 - - 0.0000004605 59.0
HFD3_k127_5864292_3 Domain of unknown function (DUF4388) - - - 0.0004594 51.0
HFD3_k127_587515_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000006394 244.0
HFD3_k127_587515_1 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.00000000000000000000000000000000000000000000000000000003436 226.0
HFD3_k127_587515_2 WD40-like Beta Propeller Repeat K03641 - - 0.000000000000000000000000000000000000000000843 182.0
HFD3_k127_587515_3 Hep Hag repeat protein K11904,K21449 - - 0.000000000000001896 90.0
HFD3_k127_587515_4 6-phosphogluconolactonase activity - - - 0.000000009142 70.0
HFD3_k127_587650_0 Uncharacterised nucleotidyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000001387 228.0
HFD3_k127_587650_2 signal peptide processing K13280 - 3.4.21.89 0.0000000006316 66.0
HFD3_k127_5876967_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006884 583.0
HFD3_k127_5880733_0 AntiSigma factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003235 260.0
HFD3_k127_5880733_1 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000000000006074 206.0
HFD3_k127_5880733_2 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000008949 177.0
HFD3_k127_5886085_0 - - - - 0.0000000000000000005264 89.0
HFD3_k127_5886085_1 Transcription factor K07736 - - 0.0000000001685 68.0
HFD3_k127_5888319_0 TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001642 256.0
HFD3_k127_5893283_0 ATP-dependent DNA helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 556.0
HFD3_k127_5893283_1 DNA polymerase A domain K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000002764 269.0
HFD3_k127_5893283_2 PFAM isochorismatase hydrolase - - - 0.0000000000000000000000000000000000000001931 156.0
HFD3_k127_5893283_3 Glycosyl transferase family 41 - - - 0.0000001638 63.0
HFD3_k127_5895637_0 Amidohydrolase family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000008026 206.0
HFD3_k127_5895637_1 Similarity to COG0471 Di- and tricarboxylate transporters(Evalue K14445 - - 0.0000000000000000001405 91.0
HFD3_k127_5895637_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K16079 - - 0.000000000000000000644 94.0
HFD3_k127_5899044_0 efflux transmembrane transporter activity K02004 - - 9.737e-217 700.0
HFD3_k127_5899044_1 lipoprotein transporter activity K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001029 250.0
HFD3_k127_5899044_2 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000001234 253.0
HFD3_k127_5899044_3 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000001573 138.0
HFD3_k127_591055_0 thymidylate synthase (FAD) activity K03465 - 2.1.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000004284 256.0
HFD3_k127_59107_0 virulence factor MVIN family protein K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006573 415.0
HFD3_k127_5920588_0 SPFH domain / Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 297.0
HFD3_k127_5920588_1 Iron-sulfur cluster loop - - - 0.000000195 59.0
HFD3_k127_5924147_0 Glucuronate isomerase K01812 - 5.3.1.12 3.556e-209 659.0
HFD3_k127_5924147_1 ABC-type sugar transport system periplasmic component K02058,K10439 - - 0.00000000000000000000000000000000000000000000000000006502 198.0
HFD3_k127_5924147_2 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.00000000000000000000000000000000000000000000000001619 181.0
HFD3_k127_592929_0 PFAM Class II aldolase adducin K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000000000000001036 237.0
HFD3_k127_592929_1 BMC - - - 0.0000000000000000000000000000000004113 132.0
HFD3_k127_592929_2 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.0000000000000000000000000005107 116.0
HFD3_k127_592929_3 - - - - 0.00000006961 61.0
HFD3_k127_5950170_0 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 610.0
HFD3_k127_5950170_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 375.0
HFD3_k127_5950170_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000004117 205.0
HFD3_k127_5950170_3 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000001225 128.0
HFD3_k127_5955965_0 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000000000000000000000000000000000000000001034 188.0
HFD3_k127_5957566_0 C-terminal domain of CHU protein family - - - 0.000000000000000000000000000000003494 147.0
HFD3_k127_5957652_0 Peptidase family C25 - - - 0.000000000000000000000000000000000000000000000000000000000002279 233.0
HFD3_k127_5970491_0 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000004175 216.0
HFD3_k127_5970491_1 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000008904 207.0
HFD3_k127_5970491_2 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0000000000000000000000000000000000000000000000000006176 188.0
HFD3_k127_5970491_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000007794 180.0
HFD3_k127_5970491_4 Binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000003564 166.0
HFD3_k127_5970491_5 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000000000003591 164.0
HFD3_k127_5970491_6 Ribosomal protein L30 K02907 - - 0.0000000000000000001858 91.0
HFD3_k127_5970491_7 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000001603 80.0
HFD3_k127_5971934_0 Tricorn protease C1 domain K08676 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 607.0
HFD3_k127_5976332_0 Domain of unknown function (DUF4123) - - - 0.000000000000000005309 89.0
HFD3_k127_5977911_0 serine-type peptidase activity - - - 3.077e-250 796.0
HFD3_k127_5977911_1 Mur ligase middle domain protein K02558 - 6.3.2.45 0.00000000000000000000000000000000000000000000000000000000000000000000004394 247.0
HFD3_k127_5977911_2 PFAM OsmC-like protein K07397 - - 0.0008282 42.0
HFD3_k127_5978637_0 PFAM Type II secretion system protein E K02652 - - 7.399e-210 668.0
HFD3_k127_5978637_1 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000004781 94.0
HFD3_k127_5978637_2 type II and III secretion system protein K02453 - - 0.00001723 51.0
HFD3_k127_5990115_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005269 438.0
HFD3_k127_5990115_1 Peptidase family C25 - - - 0.00000000000000000000000000000000000005883 164.0
HFD3_k127_5990115_2 PFAM single-stranded nucleic acid binding R3H K06346 - - 0.000000000002844 67.0
HFD3_k127_5990115_3 Pentapeptide repeats (9 copies) - - - 0.00002593 48.0
HFD3_k127_5990947_0 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000009929 191.0
HFD3_k127_5990947_1 - - - - 0.00000000003 73.0
HFD3_k127_5990947_2 PD-(D/E)XK nuclease superfamily K01144,K03406,K03582,K03658,K07464,K16898,K19465 GO:0000166,GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008854,GO:0009314,GO:0009338,GO:0009628,GO:0009987,GO:0015616,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016895,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032392,GO:0032508,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044355,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0099046,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.1.11.5,3.1.12.1,3.6.4.12 0.0000264 51.0
HFD3_k127_5996030_0 LVIVD repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 447.0
HFD3_k127_5996030_1 - K11891,K16091 - - 0.0000000000000000000000000000000000000005926 154.0
HFD3_k127_60118_0 Fibronectin type III domain - - - 0.000000000000000000000000000000000000000001155 171.0
HFD3_k127_6012235_0 lipopolysaccharide transport K22110 - - 0.0 1090.0
HFD3_k127_6013984_0 Required for morphogenesis under gluconeogenic growth conditions - - - 0.0000000000000000000000000000000000000000000000000128 184.0
HFD3_k127_6013984_1 Uroporphyrinogen-III synthase K01719,K13542 - 2.1.1.107,4.2.1.75 0.000000000000000000001912 97.0
HFD3_k127_6013984_2 Tetratricopeptide repeat - - - 0.00000000000677 76.0
HFD3_k127_6014186_0 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 398.0
HFD3_k127_6014186_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000001359 83.0
HFD3_k127_601938_0 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 340.0
HFD3_k127_601938_1 Sigma-54 interaction domain K15836 - - 0.000000000000000000003419 99.0
HFD3_k127_601938_2 ABC-2 family transporter protein K01992 - - 0.000000000000000001527 90.0
HFD3_k127_601938_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.000000000001876 67.0
HFD3_k127_601938_4 transcription factor binding K02584,K12146,K12266,K15836,K21009 GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141 - 0.0000004763 53.0
HFD3_k127_6028085_0 Integrin alpha (beta-propellor repeats). - - - 0.00000000000000000000000000000000000000000000000000585 205.0
HFD3_k127_6028085_1 Cold shock protein domain K03704 - - 0.0000000000000000000000001124 107.0
HFD3_k127_6028085_2 - - - - 0.000000000001079 75.0
HFD3_k127_6036493_0 serine-type peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 346.0
HFD3_k127_6038451_0 oxidoreductase activity - - - 1.152e-202 646.0
HFD3_k127_6038451_1 Associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007115 399.0
HFD3_k127_6038451_2 - - - - 0.00000000000000000000000000000000000000000000009006 182.0
HFD3_k127_6038451_3 - - - - 0.00000000000000000000000000000000000000009981 157.0
HFD3_k127_6038890_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 390.0
HFD3_k127_6038890_1 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000009032 183.0
HFD3_k127_6038890_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000001787 123.0
HFD3_k127_6038890_3 ACT domain - - - 0.000000001118 66.0
HFD3_k127_6039946_0 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 313.0
HFD3_k127_6039946_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000001308 213.0
HFD3_k127_6045492_0 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000008121 155.0
HFD3_k127_6045492_1 Carboxypeptidase regulatory-like domain - - - 0.000004154 53.0
HFD3_k127_6048163_0 Spermidine putrescine-binding periplasmic protein K11069,K11070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 485.0
HFD3_k127_605084_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404 519.0
HFD3_k127_605084_1 Heparinase II/III-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004455 256.0
HFD3_k127_605084_2 Glycosyl transferase family 4 K02851 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000003794 175.0
HFD3_k127_605084_3 capsular - - - 0.00000000000000000000000000000000000000004481 156.0
HFD3_k127_605084_4 Heparinase II/III N-terminus - - - 0.00000000000000000000000000003062 126.0
HFD3_k127_6057233_0 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 475.0
HFD3_k127_6057233_1 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.00000000000000000000000000000000000004063 145.0
HFD3_k127_6059409_0 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760,K15780 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8,6.3.4.19 0.000000000000000000000000000000000000000000000007062 174.0
HFD3_k127_6069022_0 Polysaccharide deacetylase - - - 0.00000000000000000006696 102.0
HFD3_k127_6069022_1 DolP-mannose mannosyltransferase - GO:0000030,GO:0003674,GO:0003824,GO:0004169,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006486,GO:0006493,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019538,GO:0034645,GO:0035268,GO:0035269,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044464,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.0001378 53.0
HFD3_k127_607111_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 453.0
HFD3_k127_607111_1 PFAM ADP-ribosylglycohydrolase K05521 - 3.2.2.24 0.00000000000000000000000000000000000000000001108 165.0
HFD3_k127_6075951_0 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 521.0
HFD3_k127_6081177_0 type II secretion system protein K - - - 0.0000000000000000000000896 115.0
HFD3_k127_6085102_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 306.0
HFD3_k127_6085102_1 response regulator K02485 - - 0.000000000000000000000000000000000000000000000000000001722 194.0
HFD3_k127_6085102_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000001702 151.0
HFD3_k127_6085102_3 PAS fold - - - 0.00000000000000000000000000006273 116.0
HFD3_k127_6089764_0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 497.0
HFD3_k127_6089764_1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000004135 242.0
HFD3_k127_6089764_2 Domain of unknown function (DUF1977) K09518 GO:0001671,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0006457,GO:0006508,GO:0006511,GO:0006807,GO:0006950,GO:0008047,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010033,GO:0010243,GO:0010498,GO:0012505,GO:0016020,GO:0019538,GO:0019941,GO:0030163,GO:0030234,GO:0030433,GO:0030544,GO:0031072,GO:0031984,GO:0032781,GO:0033554,GO:0034975,GO:0034976,GO:0036503,GO:0042175,GO:0042221,GO:0043085,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043462,GO:0043632,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0050790,GO:0050896,GO:0051336,GO:0051345,GO:0051603,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071704,GO:0098772,GO:0098827,GO:1901564,GO:1901565,GO:1901575,GO:1901698 - 0.00001546 57.0
HFD3_k127_6092700_0 Universal stress protein family - - - 0.0000000000000000000000000000000000000008878 160.0
HFD3_k127_6092700_1 AMP binding - - - 0.00000000000000000000000000000123 129.0
HFD3_k127_6092700_2 SPTR Pyridoxamine 5'-phosphate oxidase-related FMN-binding protein K07005 - - 0.0000000000000000000000003325 110.0
HFD3_k127_6094462_0 D5 N terminal like K06919 - - 0.000000000000000000000000009932 118.0
HFD3_k127_6094462_2 DNA excision - - - 0.000000000000000276 83.0
HFD3_k127_6100865_0 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001229 258.0
HFD3_k127_6101226_0 PQQ enzyme repeat K00117 - 1.1.5.2 1.168e-298 932.0
HFD3_k127_6101226_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 556.0
HFD3_k127_6101226_2 - - - - 0.00005363 51.0
HFD3_k127_6102012_0 serine-type peptidase activity K01278 - 3.4.14.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 576.0
HFD3_k127_6102171_0 transferase hexapeptide K13018 - 2.3.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 293.0
HFD3_k127_6102171_1 Belongs to the ArsC family K00537 - 1.20.4.1 0.000000000000000000000000000000000000009939 149.0
HFD3_k127_6102171_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.00000000000000000000000000000002401 130.0
HFD3_k127_6102171_3 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000002508 77.0
HFD3_k127_6103489_0 Vault protein inter-alpha-trypsin domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 562.0
HFD3_k127_6103489_1 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000000000000000000004996 204.0
HFD3_k127_6103489_2 Protein of unknown function (DUF541) - - - 0.000000000000000000000000000000000005585 148.0
HFD3_k127_6103672_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 347.0
HFD3_k127_6103672_1 Phage integrase, N-terminal SAM-like domain K03733,K04763 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000064 175.0
HFD3_k127_6103672_2 DNA-templated transcription, initiation K03088 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0010565,GO:0016020,GO:0019216,GO:0019217,GO:0019222,GO:0030312,GO:0031323,GO:0044464,GO:0050789,GO:0050794,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090 - 0.00000000000000000000000000000000000000000004243 168.0
HFD3_k127_6103672_3 Anti-sigma factor K07167 - - 0.0000000000002006 79.0
HFD3_k127_610529_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000721 203.0
HFD3_k127_610529_1 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000001745 125.0
HFD3_k127_610529_2 tail specific protease K03797 - 3.4.21.102 0.0000000000000000000000002577 109.0
HFD3_k127_6110241_0 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 528.0
HFD3_k127_6110241_1 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 - 1.1.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 397.0
HFD3_k127_6110241_2 Thg1 C terminal domain - - - 0.00000000000000000000000000002258 120.0
HFD3_k127_6110241_3 AAA domain K01090 - 3.1.3.16 0.000000001775 61.0
HFD3_k127_6112539_0 Putative Ig domain - - - 0.000000000000000000000000000000000000009657 166.0
HFD3_k127_6112539_1 alpha beta - - - 0.00000000000000000000009184 115.0
HFD3_k127_6112539_2 Fibronectin, type III domain - - - 0.0002422 54.0
HFD3_k127_6117703_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006577 257.0
HFD3_k127_6117703_1 CHRD domain - - - 0.00000000000000000000000000000008463 129.0
HFD3_k127_6117703_2 Belongs to the peptidase S8 family - - - 0.0000001627 61.0
HFD3_k127_6122496_0 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 549.0
HFD3_k127_6122496_1 PFAM glycoside hydrolase, family 29 K01206 - 3.2.1.51 0.000000000000000000002393 95.0
HFD3_k127_6127857_0 PFAM carbon monoxide dehydrogenase subunit G K09386 - - 0.00000000000000000000000000000000000002256 151.0
HFD3_k127_6127857_1 Outer membrane efflux protein K12340 - - 0.00000000002243 66.0
HFD3_k127_6128701_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 435.0
HFD3_k127_6128701_1 protein kinase activity - - - 0.000000000000000000000000000000001911 147.0
HFD3_k127_6128701_2 Sulfatase-modifying factor enzyme 1 - - - 0.0000008487 62.0
HFD3_k127_6130419_0 transmembrane transporter activity K08191 - - 4.114e-195 617.0
HFD3_k127_6130419_1 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006587 594.0
HFD3_k127_6130419_2 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 360.0
HFD3_k127_6130419_3 PFAM KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000001313 57.0
HFD3_k127_6138168_0 cell redox homeostasis K02199 - - 0.00000000000000000000006869 106.0
HFD3_k127_6138168_1 COG1024 Enoyl-CoA hydratase carnithine racemase - - - 0.00000000000000000001472 96.0
HFD3_k127_6138168_2 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000000005537 81.0
HFD3_k127_6138168_3 - - - - 0.0000001673 55.0
HFD3_k127_6138168_4 - - - - 0.00005684 46.0
HFD3_k127_6141453_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 4.162e-242 770.0
HFD3_k127_6141453_2 General stress protein - - - 0.00004383 52.0
HFD3_k127_6147243_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000008171 186.0
HFD3_k127_6147243_1 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000008682 116.0
HFD3_k127_6147243_2 - - - - 0.000000028 61.0
HFD3_k127_615112_0 Belongs to the LarC family K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 354.0
HFD3_k127_615112_1 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 346.0
HFD3_k127_615112_2 modulates the activities of several proteins which are inactive in their K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000007326 235.0
HFD3_k127_615112_3 - - - - 0.00000000000003508 81.0
HFD3_k127_615494_0 TIGRFAM phosphate ABC transporter, phosphate-binding protein K02040 - - 0.000000000000000000000000000000000000000000000000000000000003188 214.0
HFD3_k127_615494_1 - - - - 0.000000000000007243 84.0
HFD3_k127_6156049_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 457.0
HFD3_k127_6156049_1 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.0000000000000000000000000000000000000000000006706 168.0
HFD3_k127_6156399_0 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000002178 230.0
HFD3_k127_6156399_1 - - - - 0.0000000000000000005468 95.0
HFD3_k127_6156399_2 Calcineurin-like phosphoesterase - - - 0.000000000000005631 78.0
HFD3_k127_6158049_0 aminopeptidase K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 503.0
HFD3_k127_6159405_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006901 291.0
HFD3_k127_6159405_1 FMN-dependent dehydrogenase K16422 - 1.1.3.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007537 295.0
HFD3_k127_6159405_2 - - - - 0.0000000000000000000000000405 112.0
HFD3_k127_6159405_3 Heat shock 70 kDa protein K18640 - - 0.0000000009776 70.0
HFD3_k127_6167622_0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002673 312.0
HFD3_k127_6167622_1 translation initiation inhibitor yjgF family - - - 0.0000000000000000000000000000000000004621 143.0
HFD3_k127_6172518_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000002675 220.0
HFD3_k127_6172518_1 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000001619 174.0
HFD3_k127_6172518_2 B-1 B cell differentiation - - - 0.0000000000000000000000000000352 136.0
HFD3_k127_6172518_3 Belongs to the peptidase S1C family K04691,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009897,GO:0009986,GO:0009987,GO:0010033,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0033554,GO:0035966,GO:0035967,GO:0042221,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0051788,GO:0070011,GO:0070887,GO:0071218,GO:0071310,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564 - 0.000000000000003619 88.0
HFD3_k127_6172518_4 alginic acid biosynthetic process K09815,K15727,K20276 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.000000006426 70.0
HFD3_k127_6172518_5 - - - - 0.00000006645 61.0
HFD3_k127_6172518_6 Domain of unknown function (DUF4384) - - - 0.000002484 58.0
HFD3_k127_6172518_7 - - - - 0.0008616 51.0
HFD3_k127_6173681_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 486.0
HFD3_k127_6173681_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 336.0
HFD3_k127_6173681_2 Protein of unknown function (DUF1385) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007727 264.0
HFD3_k127_6173681_3 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000003298 219.0
HFD3_k127_6173681_4 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000008966 114.0
HFD3_k127_6173681_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000004301 114.0
HFD3_k127_6173681_6 Hydrolase, alpha beta domain protein K06889 - - 0.0000000000000002914 89.0
HFD3_k127_6173681_7 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000003884 65.0
HFD3_k127_6173681_8 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000008518 54.0
HFD3_k127_6173899_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008705 563.0
HFD3_k127_6178333_0 Trehalose utilisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006227 428.0
HFD3_k127_6178333_1 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000008775 196.0
HFD3_k127_6178333_2 PQQ-like domain - - - 0.00000000000000000000000000007631 118.0
HFD3_k127_6179960_0 Phosphoesterase family K01114 - 3.1.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008563 434.0
HFD3_k127_6179960_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000001028 62.0
HFD3_k127_621073_0 Glycosyltransferase family 28 C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 292.0
HFD3_k127_621073_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000004433 104.0
HFD3_k127_6217999_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 396.0
HFD3_k127_6220421_0 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K01501 - 3.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009475 316.0
HFD3_k127_6220421_1 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003349 266.0
HFD3_k127_6220421_2 Protein of unknown function (DUF1326) - - - 0.00000000001137 65.0
HFD3_k127_6223326_0 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.0000000000000000000000000002461 117.0
HFD3_k127_6223326_1 Belongs to the peptidase M10A family K07761,K07999 GO:0001101,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009628,GO:0009651,GO:0009719,GO:0009725,GO:0009753,GO:0010033,GO:0010035,GO:0010038,GO:0016020,GO:0016787,GO:0019538,GO:0031224,GO:0031225,GO:0032502,GO:0040007,GO:0042221,GO:0043170,GO:0044238,GO:0044425,GO:0044464,GO:0046686,GO:0048519,GO:0048580,GO:0048583,GO:0048589,GO:0048831,GO:0050789,GO:0050793,GO:0050896,GO:0051093,GO:0051239,GO:0051241,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080186,GO:0140096,GO:1900055,GO:1900056,GO:1901564,GO:1901700,GO:1905622,GO:2000024,GO:2000026,GO:2000028,GO:2000241 - 0.00007777 55.0
HFD3_k127_622634_0 Carboxypeptidase regulatory-like domain - - - 0.00000003783 59.0
HFD3_k127_622634_1 Tetratricopeptide repeat - - - 0.00001276 57.0
HFD3_k127_6228727_0 Permease, YjgP YjgQ - - - 0.00000000000000000000000000000000004756 150.0
HFD3_k127_6228727_1 TIGRFAM VWFA-related Acidobacterial domain - - - 0.0000000000000000000000002951 114.0
HFD3_k127_6236486_0 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000001286 245.0
HFD3_k127_6236486_1 TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000004408 244.0
HFD3_k127_6238905_0 transcription factor binding K02584,K12146,K12266,K15836,K21009 GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 602.0
HFD3_k127_6239715_0 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 297.0
HFD3_k127_6239715_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000007962 242.0
HFD3_k127_6239715_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000001496 142.0
HFD3_k127_6241394_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 467.0
HFD3_k127_6241394_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 334.0
HFD3_k127_6241394_2 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000589 154.0
HFD3_k127_6243649_0 TonB-dependent Receptor Plug Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005258 292.0
HFD3_k127_6243649_1 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000005788 146.0
HFD3_k127_6246982_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 472.0
HFD3_k127_6248829_0 DEAD-like helicases superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 483.0
HFD3_k127_6248829_1 Protein of unknown function (DUF790) K09744 - - 0.0000000000000000000000000000001274 130.0
HFD3_k127_6253933_0 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006358 412.0
HFD3_k127_6257995_0 - - - - 0.00002524 56.0
HFD3_k127_6258109_0 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000002584 89.0
HFD3_k127_6258109_1 - - - - 0.0000000000588 68.0
HFD3_k127_6258109_2 Hep Hag repeat protein K11904,K21449 - - 0.0000000001011 66.0
HFD3_k127_6259588_0 Peptidase M14, carboxypeptidase A - - - 1.222e-226 726.0
HFD3_k127_6259588_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000003252 87.0
HFD3_k127_6263611_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008205 410.0
HFD3_k127_6263611_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 408.0
HFD3_k127_6263611_2 Essential cell division protein K01921,K03589,K06438 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0040007,GO:0042802,GO:0043093,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.0002961 52.0
HFD3_k127_6267024_0 Major Facilitator Superfamily K08191 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009774 541.0
HFD3_k127_6267024_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000006382 216.0
HFD3_k127_6267024_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000001099 87.0
HFD3_k127_6267024_3 Galactokinase galactose-binding signature K00849 - 2.7.1.6 0.000000000004042 79.0
HFD3_k127_6267093_0 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001083 258.0
HFD3_k127_6267093_1 Inorganic pyrophosphatase - - - 0.00000000000000000000000000000000000000000000002201 176.0
HFD3_k127_6267220_0 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 355.0
HFD3_k127_6267220_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004442 342.0
HFD3_k127_6267220_2 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 347.0
HFD3_k127_6267220_3 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000005286 172.0
HFD3_k127_6273066_0 Putative serine dehydratase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 468.0
HFD3_k127_6273066_1 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000000000003967 222.0
HFD3_k127_6275524_0 OmpA family K02557,K03286 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005039 462.0
HFD3_k127_6275524_1 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000002951 169.0
HFD3_k127_6275524_2 cheY-homologous receiver domain - - - 0.000000000000000000000000000009982 124.0
HFD3_k127_6275524_3 Transglycosylase associated protein - - - 0.00000000002068 67.0
HFD3_k127_6277828_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 560.0
HFD3_k127_6277828_1 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000000000002476 203.0
HFD3_k127_6277828_2 metallophosphoesterase K07098 - - 0.000000000000000000000000000000002442 138.0
HFD3_k127_6285291_0 Domain of unknown function (DUF1731) K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 371.0
HFD3_k127_6285291_1 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009207 362.0
HFD3_k127_6285291_3 CHASE K02488,K21009 - 2.7.7.65 0.00000000000000000000000000000000000000000000002207 183.0
HFD3_k127_6285291_4 COGs COG3372 conserved K09744 - - 0.0000000000000000000000000000000000000000000006134 173.0
HFD3_k127_6285291_5 blue (type 1) copper K00368 - 1.7.2.1 0.000000000000000008313 88.0
HFD3_k127_6295044_0 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000005562 270.0
HFD3_k127_6295044_1 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000003533 181.0
HFD3_k127_6296001_0 cell shape determining protein MreB K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004012 252.0
HFD3_k127_6296001_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000002109 183.0
HFD3_k127_6299118_0 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009922 313.0
HFD3_k127_6299118_1 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000004291 200.0
HFD3_k127_6299118_2 Peptidase family M1 domain - - - 0.00000000000003607 85.0
HFD3_k127_6303631_0 domain protein - - - 0.0000000000000000000000000000000000000000000006633 173.0
HFD3_k127_6303631_1 PFAM Integrase core domain K07497 - - 0.0000000000000006749 81.0
HFD3_k127_6303631_2 PFAM Integrase core domain K07497 - - 0.0000000004683 62.0
HFD3_k127_6315131_0 Alkaline phosphatase K01113 - 3.1.3.1 1.52e-247 782.0
HFD3_k127_6315131_1 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000003124 167.0
HFD3_k127_6315131_2 MacB-like periplasmic core domain - - - 0.000000000000000001524 87.0
HFD3_k127_6315744_0 - - - - 0.00000000000000000000000000000000000000000000006798 176.0
HFD3_k127_6315744_1 PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000002522 139.0
HFD3_k127_6325598_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000001335 241.0
HFD3_k127_6325598_1 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814,K05365 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000009849 203.0
HFD3_k127_6325598_2 Putative phosphatase (DUF442) - - - 0.00000000000000001691 90.0
HFD3_k127_6331508_0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 286.0
HFD3_k127_6331508_1 protein deglycation K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000005628 245.0
HFD3_k127_6331508_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000002599 216.0
HFD3_k127_6331508_3 Ferritin-like domain K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000003908 199.0
HFD3_k127_6331508_4 Pyridoxamine 5'-phosphate oxidase K05558 - - 0.0000000000000000000000000000000000001776 145.0
HFD3_k127_6331508_5 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000008183 49.0
HFD3_k127_633776_0 TonB dependent receptor K16090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 626.0
HFD3_k127_633776_1 Domain of unknown function (DUF4912) K09942 - - 0.00004235 55.0
HFD3_k127_6348273_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002488 267.0
HFD3_k127_6348273_1 Metallopeptidase family M24 K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000004142 239.0
HFD3_k127_6348273_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000003151 222.0
HFD3_k127_6351825_0 LytTr DNA-binding domain - - - 0.00000000000000000000000000000000000000007101 162.0
HFD3_k127_6351825_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000008349 94.0
HFD3_k127_6351825_2 Histidine kinase - - - 0.0000000002521 63.0
HFD3_k127_6353796_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 628.0
HFD3_k127_6353796_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000002024 208.0
HFD3_k127_6353796_2 Protein of unknown function (DUF3303) - - - 0.000000000000000000000000000001926 122.0
HFD3_k127_6353796_3 Domain of unknown function (DUF427) - - - 0.0000000000000000000000005317 104.0
HFD3_k127_635612_0 Phosphoesterase family K21302 - 3.1.3.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 306.0
HFD3_k127_635612_1 Protein of unknown function (DUF1349) - - - 0.00000000000000001644 95.0
HFD3_k127_6356526_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.469e-207 655.0
HFD3_k127_6356526_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075,K15780 - 2.4.2.8,6.3.4.19 0.00000000000000000000000000000000000000000002063 182.0
HFD3_k127_6356526_2 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.000000000001898 68.0
HFD3_k127_6357496_0 Hep Hag repeat protein - - - 0.0000000000000000000000000002699 130.0
HFD3_k127_6357496_1 Hep Hag repeat protein K11904,K21449 - - 0.0000000000000001087 95.0
HFD3_k127_6357496_2 tail collar domain protein - - - 0.00000000006882 73.0
HFD3_k127_6368647_0 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 486.0
HFD3_k127_6368647_1 helix_turn_helix, arabinose operon control protein K07506 - - 0.00000000000000000000000000000000000000000000000000000000000000000006821 242.0
HFD3_k127_6368647_2 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000008408 112.0
HFD3_k127_6368647_3 SnoaL-like domain - - - 0.00005131 46.0
HFD3_k127_6369610_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 346.0
HFD3_k127_6369610_1 response regulator - - - 0.000000000000000000000000000000000000000000005086 171.0
HFD3_k127_6369610_2 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000006932 161.0
HFD3_k127_6369610_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000008905 65.0
HFD3_k127_6373647_0 Protein of unknown function (DUF2723) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000585 274.0
HFD3_k127_6373647_1 - - - - 0.00000000000000000000000000000000000000000000000000000001494 207.0
HFD3_k127_6373647_3 Xylose isomerase-like TIM barrel K01816 - 5.3.1.22 0.000000001674 62.0
HFD3_k127_6374356_0 AAA ATPase domain K01768 - 4.6.1.1 0.000002056 60.0
HFD3_k127_6377343_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 2.304e-266 854.0
HFD3_k127_6379911_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 330.0
HFD3_k127_6379911_1 peroxiredoxin activity K01607 - 4.1.1.44 0.00000000000000000000000000000000000001493 146.0
HFD3_k127_6379911_2 - - - - 0.00000000000005434 79.0
HFD3_k127_6389304_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 5.025e-269 848.0
HFD3_k127_6389304_1 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000003727 203.0
HFD3_k127_6389304_2 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000001734 174.0
HFD3_k127_6391727_0 Peptidase S46 - - - 4.379e-212 679.0
HFD3_k127_6391727_1 Bacitracin transport ATP binding cassette transporter, ABC protein K20459 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 289.0
HFD3_k127_639670_0 short-chain dehydrogenase reductase SDR K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 375.0
HFD3_k127_639670_1 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 319.0
HFD3_k127_639670_2 Carbamoyltransferase C-terminus K00612 - - 0.00000000000000000000000000000000000000000000000000000000000000001476 230.0
HFD3_k127_639670_3 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000212 231.0
HFD3_k127_639670_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000136 128.0
HFD3_k127_639670_5 - - - - 0.00000000000008522 82.0
HFD3_k127_639670_6 - - - - 0.0000000000001909 80.0
HFD3_k127_6397724_0 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 292.0
HFD3_k127_6397724_1 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000369 239.0
HFD3_k127_6397724_2 DinB family - - - 0.0000000006665 59.0
HFD3_k127_6398382_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00066 - 1.1.1.132 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 448.0
HFD3_k127_6398382_1 Methyltransferase FkbM domain - - - 0.00000000000000000006306 100.0
HFD3_k127_6413429_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005247 596.0
HFD3_k127_6413429_1 repeat-containing protein - - - 0.0000000000000000000000000000000003945 140.0
HFD3_k127_6413429_2 - - - - 0.000000004514 64.0
HFD3_k127_6416798_0 Mate efflux family protein K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000811 500.0
HFD3_k127_6428442_0 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005672 343.0
HFD3_k127_6428442_1 amine dehydrogenase activity K14647,K21449 - - 0.000000000000000000000000000000000000000000000000000000000502 224.0
HFD3_k127_6431703_0 Sortilin, neurotensin receptor 3, - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009601 358.0
HFD3_k127_6433281_0 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 378.0
HFD3_k127_6433281_1 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000009871 185.0
HFD3_k127_6435525_0 heat shock protein 70 K04043,K04044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 567.0
HFD3_k127_6435525_1 PFAM heat shock protein DnaJ K04082 - - 0.00000000000000000000000000000000000000000000001313 179.0
HFD3_k127_6435525_2 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000009402 114.0
HFD3_k127_6435525_3 Protein of unknown function (DUF433) - - - 0.0000000000001835 74.0
HFD3_k127_6436046_0 FES K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000738 194.0
HFD3_k127_6440111_0 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000007533 230.0
HFD3_k127_6440111_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - - 0.0000000000000000003137 102.0
HFD3_k127_6440180_0 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 519.0
HFD3_k127_6440180_1 PFAM D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.0001259 48.0
HFD3_k127_6449838_0 Tricorn protease PDZ domain K08676 - - 0.0 1311.0
HFD3_k127_6449838_1 Belongs to the HpcH HpaI aldolase family K08691 - 4.1.3.24,4.1.3.25 0.0000006982 56.0
HFD3_k127_6451805_0 thiolester hydrolase activity K19188 - 3.7.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 384.0
HFD3_k127_6458602_0 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008674 287.0
HFD3_k127_6458602_1 - - - - 0.000000000000000000000000000000000000000000006078 169.0
HFD3_k127_6458602_3 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000003584 60.0
HFD3_k127_6458602_4 bacterial-type flagellum-dependent cell motility - - - 0.00007066 46.0
HFD3_k127_6461916_0 Protein kinase domain K12132 - 2.7.11.1 2.068e-259 830.0
HFD3_k127_6461916_1 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 321.0
HFD3_k127_6461916_10 amino acid K03294 - - 0.0006171 45.0
HFD3_k127_6461916_2 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003973 310.0
HFD3_k127_6461916_3 pfam abc K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001302 280.0
HFD3_k127_6461916_4 DNA-templated transcription, initiation K02405 - - 0.000000000000000000000000000000000000000000000000000000004582 204.0
HFD3_k127_6461916_5 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000000000414 144.0
HFD3_k127_6461916_6 ErfK YbiS YcfS YnhG K16291 - - 0.00000000000000001635 96.0
HFD3_k127_6461916_7 - - - - 0.00000000000008181 74.0
HFD3_k127_6461916_8 Belongs to the MlaE permease family K02066 - - 0.000000001159 59.0
HFD3_k127_6461916_9 - - - - 0.0000000639 57.0
HFD3_k127_64652_0 Tricorn protease PDZ domain K08676 - - 0.0 1336.0
HFD3_k127_64652_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 2.444e-237 751.0
HFD3_k127_64652_2 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 403.0
HFD3_k127_64652_3 methyltransferase - - - 0.0000000000000000000000000586 120.0
HFD3_k127_6465251_0 4Fe-4S single cluster domain K06937 - - 3.612e-250 777.0
HFD3_k127_6465251_1 Prolipoprotein diacylglyceryl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000001021 227.0
HFD3_k127_6465251_2 Hep Hag repeat protein K02536,K21449 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.0000000000000000000000000000000000001779 159.0
HFD3_k127_6465251_3 - - - - 0.000000009261 61.0
HFD3_k127_6465251_4 Hep Hag repeat protein - - - 0.00002694 57.0
HFD3_k127_6466431_0 von Willebrand factor, type A K07114 - - 0.0000000000000000000001306 111.0
HFD3_k127_6469265_0 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006145 349.0
HFD3_k127_6469265_1 Glycosyl hydrolase family 57 K16149 - 2.4.1.18 0.000000000000000000000000000000000000000000000000000001309 196.0
HFD3_k127_6469265_2 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000001918 162.0
HFD3_k127_6471376_0 Virulence factor BrkB K07058 - - 0.000000000000000000000000301 116.0
HFD3_k127_6471376_1 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000001477 113.0
HFD3_k127_6471376_2 von Willebrand factor, type A - - - 0.000000000000000000000004617 107.0
HFD3_k127_647949_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 336.0
HFD3_k127_6482298_0 Tricorn protease homolog - - - 2.435e-302 946.0
HFD3_k127_6486289_0 Protein of unknown function (DUF421) - - - 0.0000000000000000000000000000000000000000000000004205 185.0
HFD3_k127_6486289_1 Transcriptional regulator K12132 - 2.7.11.1 0.000000000000001887 89.0
HFD3_k127_6487172_0 efflux transmembrane transporter activity K02004 - - 4.055e-212 683.0
HFD3_k127_6487172_1 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000004628 127.0
HFD3_k127_6488992_0 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 368.0
HFD3_k127_6488992_1 Tetratricopeptide repeat - - - 0.000000009759 62.0
HFD3_k127_648986_0 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.000000000000002083 79.0
HFD3_k127_6491826_0 PhoD-like phosphatase K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 315.0
HFD3_k127_6493003_0 ATPase P-type (Transporting), HAD superfamily, subfamily IC K01535,K01537 - 3.6.3.6,3.6.3.8 1.553e-311 975.0
HFD3_k127_6493003_1 Transcriptional regulator K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 379.0
HFD3_k127_6493003_2 Hep Hag repeat protein - - - 0.00000000000000000000000000000000000000000001019 185.0
HFD3_k127_6493003_3 response regulator, receiver - - - 0.00000000000000000006758 93.0
HFD3_k127_6493003_4 Belongs to the universal stress protein A family - GO:0008150,GO:0040007 - 0.00000000000000004077 92.0
HFD3_k127_6495218_0 Domain of unknown function (DUF4976) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 606.0
HFD3_k127_6498338_0 Cys/Met metabolism PLP-dependent enzyme K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 548.0
HFD3_k127_6498338_1 Histidine kinase K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 305.0
HFD3_k127_6498338_2 response regulator, receiver K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000225 240.0
HFD3_k127_6498338_3 Peptidase family C25 - - - 0.000000134 60.0
HFD3_k127_6498671_0 Transposase, Mutator family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008822 483.0
HFD3_k127_6498671_1 Divalent cation transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 340.0
HFD3_k127_6498671_2 transposase activity - - - 0.000004706 51.0
HFD3_k127_6501577_0 Ankyrin repeats (many copies) - - - 0.000000000000000000000000000000000000000000000000000003952 203.0
HFD3_k127_6501577_1 Ankyrin repeats (many copies) K06015,K06867,K06886 - 3.5.1.81 0.0000000000000000000001601 100.0
HFD3_k127_6501577_2 Hep Hag repeat protein K11904,K21449 - - 0.0000000000000000002583 102.0
HFD3_k127_6501577_3 tail collar domain protein - - - 0.00000000000006992 84.0
HFD3_k127_6501577_4 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.000000008217 56.0
HFD3_k127_6513011_0 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 345.0
HFD3_k127_6513011_1 PFAM O-antigen polymerase - - - 0.0000000000001366 83.0
HFD3_k127_6516557_0 Deoxyhypusine synthase K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 324.0
HFD3_k127_6516557_1 Photosynthesis system II assembly factor YCF48 - - - 0.0000000000000000000000002217 111.0
HFD3_k127_6516557_2 Gram-negative bacterial TonB protein C-terminal - - - 0.00000000007993 73.0
HFD3_k127_6516557_3 TIGRFAM TonB K03832 - - 0.000003049 59.0
HFD3_k127_6516557_4 Roadblock/LC7 domain - - - 0.00002464 52.0
HFD3_k127_652285_0 PFAM Outer membrane efflux protein - - - 0.000000000000000000000000000000006242 144.0
HFD3_k127_6530322_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000005516 171.0
HFD3_k127_6530322_1 Anti-sigma W factor - - - 0.0000568 48.0
HFD3_k127_6531200_0 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005907 369.0
HFD3_k127_6531200_1 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000004473 268.0
HFD3_k127_6531200_2 uroporphyrinogen decarboxylase activity K01599 - 4.1.1.37 0.000000000000000000000000002963 113.0
HFD3_k127_6536131_0 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 591.0
HFD3_k127_6536131_1 Di-haem oxidoreductase, putative peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006378 271.0
HFD3_k127_653904_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 496.0
HFD3_k127_653904_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K01990 - - 0.000000000000000000000001151 117.0
HFD3_k127_6541708_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000001034 228.0
HFD3_k127_6541708_1 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000000141 134.0
HFD3_k127_655114_0 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.00000000000000000000000000000002451 143.0
HFD3_k127_655114_1 Transcriptional regulator - - - 0.00000000000004928 85.0
HFD3_k127_655946_0 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 327.0
HFD3_k127_655946_1 oligoendopeptidase F - - - 0.0000000000000000000000000000000000000003928 155.0
HFD3_k127_6559979_0 dihydroorotate dehydrogenase activity K00254,K02823,K17828 GO:0000166,GO:0003674,GO:0003824,GO:0004152,GO:0004158,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0016020,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0032553,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004952 299.0
HFD3_k127_6559979_1 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000001601 210.0
HFD3_k127_6559979_2 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.0000000000000000000000000000000000000002435 154.0
HFD3_k127_6562225_0 2-dehydropantoate 2-reductase activity K00077 - 1.1.1.169 0.0000000000000000000000000000000000000003541 164.0
HFD3_k127_6568213_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006135 590.0
HFD3_k127_6568213_1 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000003948 126.0
HFD3_k127_6568213_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000007852 69.0
HFD3_k127_6574697_0 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 462.0
HFD3_k127_6574697_1 amino acid transport K03294,K11737 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 322.0
HFD3_k127_6574697_2 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001565 273.0
HFD3_k127_6574697_3 Belongs to the 5'-nucleotidase family K01119 - 3.1.3.6,3.1.4.16 0.00000000000000000001957 102.0
HFD3_k127_6575511_0 domain protein - - - 1.453e-228 721.0
HFD3_k127_6576312_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000633 589.0
HFD3_k127_6576312_1 Belongs to the UPF0145 family - - - 0.000000000000000000000000000000000000000003104 159.0
HFD3_k127_6583136_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000664 159.0
HFD3_k127_6583136_1 Biotin-requiring enzyme - - - 0.0000000000000000000000004 111.0
HFD3_k127_6583161_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 422.0
HFD3_k127_6583161_1 ATPase activity K02045 - 3.6.3.25 0.0000000000000000000000000001726 128.0
HFD3_k127_6594322_0 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 557.0
HFD3_k127_6597516_0 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 563.0
HFD3_k127_6597516_1 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000000007616 150.0
HFD3_k127_6598300_0 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001383 258.0
HFD3_k127_6598300_1 PFAM RNA-binding protein AU-1 Ribonuclease E G K08301 - - 0.000000000000000000003253 102.0
HFD3_k127_6598300_2 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 0.000000000004064 72.0
HFD3_k127_6601190_0 5'-nucleotidase - - - 0.0000000000000000000000000000000000000007324 158.0
HFD3_k127_6601190_1 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000003533 150.0
HFD3_k127_6601190_2 Protein of unknown function (DUF721) - - - 0.00001744 53.0
HFD3_k127_660258_0 - - - - 0.00000000000000000000000000000000007589 149.0
HFD3_k127_660258_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000237 78.0
HFD3_k127_6608262_0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 344.0
HFD3_k127_6608262_1 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000434 278.0
HFD3_k127_6608262_2 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002268 254.0
HFD3_k127_6608262_3 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000007799 214.0
HFD3_k127_6608262_4 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000000000002532 190.0
HFD3_k127_6608262_5 GYD domain - - - 0.0000000000000000000000000000001797 126.0
HFD3_k127_6608262_6 Hep Hag repeat protein K11904,K21449 - - 0.0000001131 57.0
HFD3_k127_6610714_0 of the alpha beta superfamily K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 327.0
HFD3_k127_6610714_1 serine threonine protein kinase - - - 0.0000000000000000001663 96.0
HFD3_k127_661076_0 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004875 451.0
HFD3_k127_661076_1 Alpha beta hydrolase K00433 - 1.11.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 346.0
HFD3_k127_661076_2 Transcriptional regulator K03641 - - 0.00000000000000000000000000000000000000001645 169.0
HFD3_k127_661076_3 Alpha/beta hydrolase of unknown function (DUF1400) - - - 0.0000938 52.0
HFD3_k127_6613233_0 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.000000000000000000000000000000000000000000000000000000000000001553 243.0
HFD3_k127_6613233_1 Polysaccharide biosynthesis/export protein K01991 - - 0.00000000000000000000000000001176 132.0
HFD3_k127_6616369_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007626 444.0
HFD3_k127_6616369_1 Helix-turn-helix domain, rpiR family - - - 0.0002146 51.0
HFD3_k127_6619653_0 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 389.0
HFD3_k127_6619653_1 Heparinase II/III-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001509 301.0
HFD3_k127_6619653_2 Glycosyl transferase - - - 0.0002427 46.0
HFD3_k127_6621956_0 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005415 264.0
HFD3_k127_6621956_1 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000001003 146.0
HFD3_k127_6621956_2 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000001046 139.0
HFD3_k127_6621956_3 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000002115 136.0
HFD3_k127_6624035_0 Nickel-dependent hydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004805 490.0
HFD3_k127_6624035_1 Aldo/keto reductase family K16950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007214 387.0
HFD3_k127_6624035_2 NADH ubiquinone oxidoreductase, 20 Kd subunit K18007 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008207 383.0
HFD3_k127_6624035_3 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 375.0
HFD3_k127_6624035_4 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000004996 204.0
HFD3_k127_6628497_0 ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 289.0
HFD3_k127_6628497_1 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000786 162.0
HFD3_k127_6631257_0 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 441.0
HFD3_k127_6631257_1 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 329.0
HFD3_k127_6636121_0 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 379.0
HFD3_k127_6636121_1 Cytochrome c K00406,K08906 - - 0.000006308 52.0
HFD3_k127_6650669_0 sulfuric ester hydrolase activity K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009402 499.0
HFD3_k127_6650669_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 357.0
HFD3_k127_6651952_0 serine-type peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008491 531.0
HFD3_k127_6651952_1 Protein of unknown function (DUF3592) - - - 0.000000003088 64.0
HFD3_k127_665340_0 Sulfatase K01130 - 3.1.6.1 1.491e-257 813.0
HFD3_k127_6658065_0 ASPIC and UnbV - - - 0.000000000000000000000000007546 123.0
HFD3_k127_6660925_0 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007479 291.0
HFD3_k127_6660925_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000004315 171.0
HFD3_k127_6660925_2 Belongs to the NiCoT transporter (TC 2.A.52) family K08970 - - 0.00000000000000000000000000001888 120.0
HFD3_k127_6663001_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 509.0
HFD3_k127_6663001_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002907 261.0
HFD3_k127_6663001_2 Tetratricopeptide repeat - - - 0.00000000000002971 82.0
HFD3_k127_6665304_0 LytTr DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001423 264.0
HFD3_k127_6665304_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001305 259.0
HFD3_k127_6665304_2 Domain of unknown function (DUF4157) K01227,K01448,K03791,K13277,K17733 - 3.2.1.96,3.5.1.28 0.0000000000000005664 85.0
HFD3_k127_6675572_0 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000000000000000000000000000000000000000000000000002106 188.0
HFD3_k127_6675572_1 - - - - 0.00000000000000001069 93.0
HFD3_k127_6682347_0 Lactonase, 7-bladed beta-propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003068 288.0
HFD3_k127_6682347_1 BON domain - - - 0.00000000000000000000000000000000000000000006826 166.0
HFD3_k127_6682796_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 498.0
HFD3_k127_6682796_1 PFAM Histidine triad (HIT) protein K02503 - - 0.0000000004199 61.0
HFD3_k127_6685857_0 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000105 175.0
HFD3_k127_6686593_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004292 265.0
HFD3_k127_6686593_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000001016 211.0
HFD3_k127_6686593_2 - - - - 0.00000000000000000000000225 114.0
HFD3_k127_6686593_3 Seven times multi-haem cytochrome CxxCH - - - 0.0000002311 61.0
HFD3_k127_6688607_0 Peptidase family C25 - - - 0.0000000000000000000000000000000000000000000000000000000000000001626 248.0
HFD3_k127_6692714_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000001461 199.0
HFD3_k127_6692714_1 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.0000000000000000000000000000000000000000002066 169.0
HFD3_k127_6703245_0 Peptidase family M1 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003983 383.0
HFD3_k127_6703245_1 Phosphoenolpyruvate phosphomutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 367.0
HFD3_k127_6711379_0 Protein of unknown function (DUF1501) - - - 2.984e-244 761.0
HFD3_k127_6711379_1 gluconolactonase activity - - - 0.000000000000000000000000000000000002927 143.0
HFD3_k127_671526_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 587.0
HFD3_k127_671526_1 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000003466 142.0
HFD3_k127_6720765_0 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 573.0
HFD3_k127_6720765_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003033 255.0
HFD3_k127_6720765_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000002772 187.0
HFD3_k127_6720765_3 Domain of unknown function (DUF4252) - - - 0.000000000000000000000000000000009914 135.0
HFD3_k127_6722435_0 MacB-like periplasmic core domain - - - 4.486e-221 711.0
HFD3_k127_6722435_1 efflux transmembrane transporter activity K02004 - - 4.935e-206 669.0
HFD3_k127_6722435_10 Lipocalin-like domain - - - 0.00000000000000000003934 94.0
HFD3_k127_6722435_11 Protein of unknown function (DUF2911) - - - 0.00000000000002127 86.0
HFD3_k127_6722435_12 COG0457 FOG TPR repeat - - - 0.00000002798 64.0
HFD3_k127_6722435_2 sigma-54 factor interaction domain-containing protein - - - 1.228e-196 622.0
HFD3_k127_6722435_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006185 518.0
HFD3_k127_6722435_4 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 367.0
HFD3_k127_6722435_5 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005351 357.0
HFD3_k127_6722435_6 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 318.0
HFD3_k127_6722435_7 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000369 199.0
HFD3_k127_6722435_8 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000001916 186.0
HFD3_k127_6722435_9 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000198 142.0
HFD3_k127_6726581_0 PFAM Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000001069 171.0
HFD3_k127_6726581_1 Homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000001195 175.0
HFD3_k127_6726581_2 Protein of unknown function (DUF1573) - - - 0.0000000000000006068 82.0
HFD3_k127_6731614_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 1.649e-224 701.0
HFD3_k127_6731614_1 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.0000000000000000000000000000004651 125.0
HFD3_k127_673269_0 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005568 381.0
HFD3_k127_673269_1 addiction module antidote protein, CC2985 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000009502 248.0
HFD3_k127_673492_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008699 389.0
HFD3_k127_673492_1 Caspase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000007344 240.0
HFD3_k127_673492_2 Tetratricopeptide repeat - - - 0.000000000000000001299 98.0
HFD3_k127_674156_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 519.0
HFD3_k127_674156_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 512.0
HFD3_k127_674156_2 pyrroloquinoline quinone binding K01051 - 3.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 435.0
HFD3_k127_674156_3 PFAM Alanine dehydrogenase PNT, C-terminal domain K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000007684 167.0
HFD3_k127_674156_4 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.00000000000000000000000000000000001799 138.0
HFD3_k127_674156_5 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000004301 126.0
HFD3_k127_6747134_0 myo-inosose-2 dehydratase activity - - - 0.000000000000000000000000000000000000000000000000000000002112 208.0
HFD3_k127_6747134_1 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000002708 153.0
HFD3_k127_6752176_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 567.0
HFD3_k127_6752176_1 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000000001903 231.0
HFD3_k127_6752176_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000001306 224.0
HFD3_k127_6754791_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000009463 242.0
HFD3_k127_6754791_1 GGDEF domain - - - 0.0000000000001948 77.0
HFD3_k127_6756294_0 Domain of unknown function (DUF4070) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004155 521.0
HFD3_k127_6756294_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003862 261.0
HFD3_k127_6756294_2 - - - - 0.000000000000000000000000000000000000000000000000000003825 203.0
HFD3_k127_6756294_3 Transcriptional regulator, Crp Fnr family K10914 - - 0.00000000000000000000000000000000000000000000000000217 190.0
HFD3_k127_6756294_4 PFAM Rubrerythrin - - - 0.000000000000000000000004459 107.0
HFD3_k127_6756294_5 - - - - 0.000000000005028 68.0
HFD3_k127_6756294_6 - - - - 0.000000000009469 71.0
HFD3_k127_6756534_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009344 438.0
HFD3_k127_6756534_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 406.0
HFD3_k127_6756534_2 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000005588 74.0
HFD3_k127_67600_0 Elongator protein 3, MiaB family, Radical SAM K04034 - 1.21.98.3 3.671e-224 702.0
HFD3_k127_67600_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 358.0
HFD3_k127_67600_2 PFAM Glycosyl transferase family 2 K00720 - 2.4.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006009 350.0
HFD3_k127_67600_3 YdjC-like protein K03478 - 3.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000003247 271.0
HFD3_k127_67600_4 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000069 224.0
HFD3_k127_67600_5 COG1657 Squalene cyclase K06045 - 4.2.1.129,5.4.99.17 0.00000000000000000000000000000000000000000000000000000000001059 213.0
HFD3_k127_67600_6 membrane K08978 - - 0.000000000000000000000000004272 115.0
HFD3_k127_67600_7 spore germination - - - 0.000000000000000000002091 102.0
HFD3_k127_6767206_0 endonuclease III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 326.0
HFD3_k127_6767206_1 Short chain fatty acid transporter K02106 - - 0.00000000000000000000000000000000000000000000000000000000005518 222.0
HFD3_k127_6767206_2 protein deglycase activity - - - 0.0000000000000000000000000000000006004 132.0
HFD3_k127_6785982_0 PFAM Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001324 269.0
HFD3_k127_6785982_1 PFAM Bacterial transferase hexapeptide (three repeats) - - - 0.00000000000000000000000000000000000000000000000000000000000000001007 230.0
HFD3_k127_6785982_2 Nodulation protein S (NodS) - - - 0.00000000000000000000000000000000000000000000008102 177.0
HFD3_k127_6785982_3 phenylacetate-CoA ligase activity K18538 - - 0.000002417 53.0
HFD3_k127_6798479_0 Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 293.0
HFD3_k127_6798479_1 Prolyl oligopeptidase family - - - 0.000000000000000000000000000000000000000000000000000001037 211.0
HFD3_k127_6798479_2 Shikimate kinase K00851 - 2.7.1.12 0.000000000000000000000000000000000000000000002749 169.0
HFD3_k127_6798479_3 Peptidoglycan-binding domain 1 protein - - - 0.000000000005162 76.0
HFD3_k127_6798479_4 Ankyrin repeat K06867 - - 0.0000003954 53.0
HFD3_k127_6803087_0 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 449.0
HFD3_k127_6803087_1 C-terminal, D2-small domain, of ClpB protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004012 409.0
HFD3_k127_6803087_2 Prephenate dehydratase K04518 - 4.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001756 284.0
HFD3_k127_6803087_3 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000001128 205.0
HFD3_k127_6803087_4 Stage II sporulation protein K06381 - - 0.000000000000000000000000000000000004236 159.0
HFD3_k127_6808848_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 2.931e-296 921.0
HFD3_k127_6808848_1 2Fe-2S -binding domain protein K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000001896 231.0
HFD3_k127_6808848_2 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000006722 98.0
HFD3_k127_6812069_0 iron ion homeostasis - - - 0.0000000000000000000000000000000000000000000000000001697 209.0
HFD3_k127_6812069_1 CAAX amino terminal protease family K07052 - - 0.000003178 56.0
HFD3_k127_6814114_0 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 575.0
HFD3_k127_6814114_1 Part of the ABC transporter complex XylFGH involved in xylose import. Responsible for energy coupling to the transport system K10545 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 462.0
HFD3_k127_6814114_2 carbohydrate transport K10544 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005718 434.0
HFD3_k127_6814114_3 PFAM Haloacid dehalogenase domain protein hydrolase K01560,K07025 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 289.0
HFD3_k127_6814114_4 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000001152 220.0
HFD3_k127_6814114_5 glyoxalase III activity - - - 0.000000000000000000000000000000000000000000000000000000000003272 214.0
HFD3_k127_6821053_0 siderophore transport K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 406.0
HFD3_k127_6829154_1 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.000000000000003324 89.0
HFD3_k127_6829154_2 COGs COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 0.000000000000004534 79.0
HFD3_k127_6836283_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 635.0
HFD3_k127_6836283_1 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000001209 205.0
HFD3_k127_6836283_2 Rab9 effector protein with kelch - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00001082 53.0
HFD3_k127_6836366_0 CDP-alcohol phosphatidyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000007285 211.0
HFD3_k127_6836366_1 Anti-sigma-K factor rskA - - - 0.00000000000000000000000000000000000000000001249 172.0
HFD3_k127_6836366_2 - - - - 0.0000000000000000000000000000005678 128.0
HFD3_k127_6836366_3 GtrA-like protein - - - 0.0000000000000000000000000002381 119.0
HFD3_k127_6843547_0 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000000000000000000000000000000000002884 231.0
HFD3_k127_685203_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 499.0
HFD3_k127_685203_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007698 301.0
HFD3_k127_685203_3 N-Acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000001292 214.0
HFD3_k127_685203_4 Peptidase, M16 K07263 - - 0.000000000000000000000000000001285 130.0
HFD3_k127_6852995_0 PQQ-like domain K05889 - 1.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005668 328.0
HFD3_k127_6852995_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000001186 188.0
HFD3_k127_6852995_2 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000004391 167.0
HFD3_k127_6852995_3 - - - - 0.0000000000000000000000000000005989 126.0
HFD3_k127_6852995_4 PFAM Metal-dependent phosphohydrolase, HD - - - 0.00000000000000000000000004206 125.0
HFD3_k127_6852995_5 Protein of unknown function (DUF465) - - - 0.000005539 52.0
HFD3_k127_6855861_0 tetratricopeptide repeat - - - 0.00000000000000000000000001948 121.0
HFD3_k127_6855861_1 - - - - 0.00000000000005213 76.0
HFD3_k127_6859713_0 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 423.0
HFD3_k127_6859713_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003872 276.0
HFD3_k127_6859713_2 ZIP Zinc transporter K07238,K11021,K16267 - - 0.00000000000000000000000000000000000000000000000000000007481 203.0
HFD3_k127_6863595_0 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 553.0
HFD3_k127_6865508_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 6.931e-238 741.0
HFD3_k127_6865508_1 Di-iron-containing protein involved in the repair of iron-sulfur clusters - - - 0.000000000000000000000000000000000007221 142.0
HFD3_k127_6865508_2 cytochrome c nitrite reductase K15876 - - 0.00000000000000000000000001574 108.0
HFD3_k127_6865508_3 YwiC-like protein - - - 0.0000000000000000001168 98.0
HFD3_k127_6865508_4 TIGRFAM cytochrome c nitrate reductase, small subunit K15876 - - 0.000000000000000005424 84.0
HFD3_k127_6873372_0 transcription factor binding K15836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 446.0
HFD3_k127_6873372_1 competence protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003945 247.0
HFD3_k127_6873372_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000271 199.0
HFD3_k127_6873389_0 Fungalysin metallopeptidase (M36) - - - 0.0000000000000000005491 91.0
HFD3_k127_6873389_1 Tetratricopeptide repeat - - - 0.00000000009001 73.0
HFD3_k127_6873427_0 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 302.0
HFD3_k127_6879481_0 Aldehyde dehydrogenase family K22445 - 1.2.99.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 411.0
HFD3_k127_6879481_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008314 337.0
HFD3_k127_6879481_2 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000003113 240.0
HFD3_k127_6879481_3 PFAM Haloacid dehalogenase domain protein hydrolase K01091 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.18 0.000000000000000000000009213 109.0
HFD3_k127_6884485_0 copper resistance - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 331.0
HFD3_k127_6884485_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000003106 90.0
HFD3_k127_6884485_2 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 0.00000000003415 66.0
HFD3_k127_6888559_0 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007607 417.0
HFD3_k127_6888559_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006966 404.0
HFD3_k127_6888559_2 Monoamine oxidase regulatory protein - - - 0.00000000000000000000000000000000000000007605 155.0
HFD3_k127_6888559_3 - - - - 0.0000001453 59.0
HFD3_k127_6888559_4 Protein of unknown function (DUF2889) - - - 0.000006218 55.0
HFD3_k127_6890074_0 glucose sorbosone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 396.0
HFD3_k127_6890074_1 Domain of unknown function (DUF1287) K09974 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000226 247.0
HFD3_k127_6890074_2 Ferredoxin - - - 0.0000000000000000000000000000000000000000000003937 170.0
HFD3_k127_6890074_3 PFAM Glucose Sorbosone dehydrogenase - - - 0.0000000000000000000000001153 123.0
HFD3_k127_6892750_0 FCD - - - 0.0000000000000000000000001133 111.0
HFD3_k127_6892750_1 DDE superfamily endonuclease - - - 0.000000000000000000000006729 107.0
HFD3_k127_6892750_2 Winged helix-turn helix - - - 0.0000000000008189 74.0
HFD3_k127_689297_0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002606 277.0
HFD3_k127_6893163_0 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.00000000000000000000000000000000000002872 158.0
HFD3_k127_6893163_1 PPIC-type PPIASE domain K03769,K03770,K03771,K07533 - 5.2.1.8 0.000000000000004205 86.0
HFD3_k127_6893861_0 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 357.0
HFD3_k127_6900974_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005733 272.0
HFD3_k127_6900974_1 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 0.0000000000000000000000000000000000000000000000000000000000000004615 228.0
HFD3_k127_690273_0 LytTr DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000001278 190.0
HFD3_k127_690273_1 LytTr DNA-binding domain K02477 - - 0.0000000000000000002654 89.0
HFD3_k127_6911016_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005268 306.0
HFD3_k127_6911016_1 AAA ATPase domain - - - 0.00000000000000000006477 98.0
HFD3_k127_6913972_0 - - - - 0.000000000000000000000000000000000000000000005614 173.0
HFD3_k127_6913972_1 Gene 25-like lysozyme K11897 - - 0.00000000000000000000000000000000000000001019 160.0
HFD3_k127_6913972_2 COG0500 SAM-dependent methyltransferases - - - 0.00002196 47.0
HFD3_k127_6913972_3 - - - - 0.00002946 51.0
HFD3_k127_6926485_0 Acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 398.0
HFD3_k127_6926485_1 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000002466 195.0
HFD3_k127_6926485_2 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.000000000000000000000000000001703 136.0
HFD3_k127_6926485_3 Glycosyl transferase, family 2 K07011 - - 0.000176 44.0
HFD3_k127_6933170_0 Tricorn protease C1 domain K08676 - - 3.856e-282 886.0
HFD3_k127_6937393_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 314.0
HFD3_k127_6937393_1 Activator of Hsp90 ATPase 1 family protein - - - 0.0000008372 56.0
HFD3_k127_6937765_0 Tetratricopeptide repeat - - - 0.000000000000001711 90.0
HFD3_k127_6939743_0 Tricorn protease C1 domain K08676 - - 8.114e-248 782.0
HFD3_k127_6939743_1 Cell wall-active antibiotics response 4TMS YvqF - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000004342 58.0
HFD3_k127_6939743_2 Carboxypeptidase regulatory-like domain - - - 0.00005042 55.0
HFD3_k127_6939743_3 Tetratricopeptide repeat - - - 0.0006456 51.0
HFD3_k127_6942029_0 efflux transmembrane transporter activity K02004 - - 7.427e-197 640.0
HFD3_k127_6942029_1 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 392.0
HFD3_k127_6942029_2 efflux transmembrane transporter activity - - - 0.00000002273 56.0
HFD3_k127_6952596_0 Amino acid transporter K03305 - - 0.00000000000000000000000000000000000000000000001036 177.0
HFD3_k127_6952596_1 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0016783,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000005287 145.0
HFD3_k127_6952596_2 Protein of unknown function (DUF3810) - - - 0.0000000000000000000000000007181 127.0
HFD3_k127_6954183_0 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006351 499.0
HFD3_k127_6954183_1 Elongator protein 3, MiaB family, Radical SAM K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000005706 267.0
HFD3_k127_6959803_0 teichoic acid transport K01990,K09689,K09691 - 3.6.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 359.0
HFD3_k127_6959803_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002221 269.0
HFD3_k127_6959803_2 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000009658 218.0
HFD3_k127_6961784_0 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000000000007661 151.0
HFD3_k127_6961784_1 Protein of unknown function (DUF3574) - - - 0.0006068 47.0
HFD3_k127_6964529_0 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 587.0
HFD3_k127_6967061_0 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 312.0
HFD3_k127_6967061_1 Trehalose utilisation K09992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003252 275.0
HFD3_k127_6967061_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001282 264.0
HFD3_k127_6971035_0 Domain of unknown function (DUF5117) - - - 2.615e-253 806.0
HFD3_k127_6971035_1 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000003546 157.0
HFD3_k127_6971035_2 phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.000000000000000000000000000000000000001112 153.0
HFD3_k127_6984076_0 Beta-lactamase - - - 1.458e-245 763.0
HFD3_k127_6984076_1 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.00000000000000000000000000000000002647 144.0
HFD3_k127_6984576_0 heavy metal translocating P-type ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 8.878e-279 880.0
HFD3_k127_6985734_0 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000764 443.0
HFD3_k127_6985734_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000001094 175.0
HFD3_k127_6985734_2 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000241 170.0
HFD3_k127_6988429_0 Peptidase family C25 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001791 279.0
HFD3_k127_6988429_1 Transcriptional regulator K03641 - - 0.00000000000000000000000000000000000000000000000000000000000679 222.0
HFD3_k127_6988874_0 Dicarboxylate carrier - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 384.0
HFD3_k127_6988874_1 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443,K16786,K16787 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000002132 201.0
HFD3_k127_6988874_2 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000662 164.0
HFD3_k127_6989584_0 coenzyme F390 synthetase K01912 - 6.2.1.30 0.000000000000000000000000000000001863 144.0
HFD3_k127_6990451_0 AMP-binding enzyme C-terminal domain K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 386.0
HFD3_k127_6990451_1 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 388.0
HFD3_k127_6990451_3 Domain of unknown function (DUF5063) - - - 0.0000000000000007312 79.0
HFD3_k127_6990451_4 Domain of unknown function (DUF5063) - - - 0.0000004037 55.0
HFD3_k127_6991120_0 Aspartyl protease - - - 0.0000003006 63.0
HFD3_k127_6991120_1 Adenylate cyclase K01768 - 4.6.1.1 0.0000003006 63.0
HFD3_k127_6991540_0 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.00000000000000000000000000000000000000000000000000000000003526 210.0
HFD3_k127_6991540_1 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.0000000000000000000000000000000000000404 147.0
HFD3_k127_6991634_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000004807 143.0
HFD3_k127_6991634_1 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.00000000002269 66.0
HFD3_k127_6997287_0 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 359.0
HFD3_k127_6997287_1 Efflux transporter, RND family, MFP subunit K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002642 265.0
HFD3_k127_6997287_2 lipopolysaccharide heptosyltransferase K02841,K02843 - - 0.00000000000000000000000000000000000009051 154.0
HFD3_k127_6997427_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 450.0
HFD3_k127_6997427_1 Zinc dependent phospholipase C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009067 246.0
HFD3_k127_6997788_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009476 326.0
HFD3_k127_6997788_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000008438 223.0
HFD3_k127_700116_0 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000002202 262.0
HFD3_k127_700116_1 Uncharacterized conserved protein (DUF2277) - - - 0.000000000000000000000000000001216 122.0
HFD3_k127_7004966_0 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000004353 197.0
HFD3_k127_7004966_1 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000002019 171.0
HFD3_k127_7004966_2 X-Pro dipeptidyl-peptidase (S15 family) K06889 - - 0.0000000000000000000000000006599 125.0
HFD3_k127_7004966_3 Pfam:N_methyl_2 - - - 0.000000000006809 69.0
HFD3_k127_7004966_4 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0008996 43.0
HFD3_k127_7010311_0 Peptidase family M1 domain - - - 0.000000000000000000000000000516 131.0
HFD3_k127_7010628_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 507.0
HFD3_k127_7010628_1 Protein of unknown function (DUF3500) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 293.0
HFD3_k127_7010628_2 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000009699 113.0
HFD3_k127_7010628_3 Ring-hydroxylating dioxygenase, large terminal subunit - - - 0.000000000000000000003245 94.0
HFD3_k127_7018581_0 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 481.0
HFD3_k127_7018581_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009554 458.0
HFD3_k127_7018581_2 Cysteine dioxygenase type I K00456 - 1.13.11.20 0.0000000000000000000000000003445 121.0
HFD3_k127_7018581_3 Mediates influx of magnesium ions K03284 - - 0.00009728 45.0
HFD3_k127_7022290_0 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 580.0
HFD3_k127_7022420_0 TIGRFAM TonB family K03832 - - 0.0000000000000000001313 99.0
HFD3_k127_7029040_0 Dienelactone hydrolase family - - - 6.185e-294 920.0
HFD3_k127_7029040_1 Zinc carboxypeptidase K01278 - 3.4.14.5 0.00000000000004348 78.0
HFD3_k127_7030213_0 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 480.0
HFD3_k127_7030213_1 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.0000000000000000000000000000000000000000006627 169.0
HFD3_k127_7031935_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298,K15408 - 1.10.3.10,1.9.3.1 2.209e-247 772.0
HFD3_k127_7031935_1 Cytochrome c oxidase subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007872 250.0
HFD3_k127_7031935_2 cytochrome c oxidase K02351 - - 0.0000000000000000000000000000000000000000000000000000000000000005532 225.0
HFD3_k127_7035033_0 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000009416 264.0
HFD3_k127_7035033_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000001616 186.0
HFD3_k127_7035033_2 Peptidase S46 - - - 0.00000000000000000000000000000000000000000003432 164.0
HFD3_k127_7035033_3 - - - - 0.00000000000005675 74.0
HFD3_k127_7037409_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007123 541.0
HFD3_k127_7037409_1 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 300.0
HFD3_k127_7037409_2 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.00000000000006164 81.0
HFD3_k127_7038755_0 von Willebrand factor, type A - - - 0.0000000000000000000000004554 109.0
HFD3_k127_7038755_1 oxidoreductase activity K12511 - - 0.000000000000000004662 95.0
HFD3_k127_7038755_2 PFAM von Willebrand factor type A - - - 0.000164 49.0
HFD3_k127_7040072_0 Thiamine pyrophosphate enzyme, central domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004725 437.0
HFD3_k127_7048397_0 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 451.0
HFD3_k127_7048397_1 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 358.0
HFD3_k127_7048397_2 Trehalose utilisation K09992 - - 0.0000000002481 61.0
HFD3_k127_7057939_0 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 443.0
HFD3_k127_7057939_1 Protein of unknown function (DUF3500) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 344.0
HFD3_k127_7057939_2 cobalamin-transporting ATPase activity - - - 0.0000000000000000000000000000000002555 141.0
HFD3_k127_7058036_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008808 346.0
HFD3_k127_7058036_1 TonB-dependent siderophore receptor K02014 - - 0.0000009381 53.0
HFD3_k127_7061563_0 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004993 433.0
HFD3_k127_7061563_1 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003685 280.0
HFD3_k127_7061563_2 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000001138 220.0
HFD3_k127_7061563_3 cAMP biosynthetic process - - - 0.00000000000000000000002958 115.0
HFD3_k127_7063183_0 Zn_pept - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 305.0
HFD3_k127_7069649_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 353.0
HFD3_k127_7082118_0 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000317 141.0
HFD3_k127_7083134_0 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000007637 167.0
HFD3_k127_7083134_1 - - - - 0.0000000000000000000000001013 123.0
HFD3_k127_7085557_0 TIGRFAM Ammonium transporter K03320 - - 9.371e-205 651.0
HFD3_k127_7085557_1 Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 484.0
HFD3_k127_7085557_2 Belongs to the P(II) protein family K04751,K04752 - - 0.000000000000000000000000000000000000000000005159 166.0
HFD3_k127_708822_0 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001216 281.0
HFD3_k127_708822_1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000003278 164.0
HFD3_k127_708822_2 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000004449 174.0
HFD3_k127_708822_3 Tetratricopeptide repeat - - - 0.000000000000002829 80.0
HFD3_k127_7089072_0 Metalloenzyme superfamily K01839 - 5.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004775 467.0
HFD3_k127_7089072_1 PFAM Stage II sporulation protein E (SpoIIE) K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000001152 216.0
HFD3_k127_7089072_2 BrnA antitoxin of type II toxin-antitoxin system - - - 0.000000000000000000000000000000002031 131.0
HFD3_k127_7089072_3 Serine aminopeptidase, S33 K07019 - - 0.000000000009931 68.0
HFD3_k127_7089072_4 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000001858 68.0
HFD3_k127_7089072_5 deoxyhypusine monooxygenase activity - - - 0.0003189 51.0
HFD3_k127_7091850_0 TIGRFAM alpha-glucan - - - 0.0 1158.0
HFD3_k127_7091850_1 Extradiol ring-cleavage dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 374.0
HFD3_k127_7091850_2 Haem-degrading - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002276 276.0
HFD3_k127_7093217_0 SpoIVB peptidase S55 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 337.0
HFD3_k127_7093217_1 Sigma-70, region 4 K03088 - - 0.000001158 59.0
HFD3_k127_7093217_2 - - - - 0.00001259 55.0
HFD3_k127_7093217_3 - - - - 0.0003803 51.0
HFD3_k127_709664_0 phosphatase homologous to the C-terminal domain of histone macroH2A1 - - - 0.000000000000000000000000000000000000721 141.0
HFD3_k127_709664_1 PFAM isocitrate isopropylmalate dehydrogenase K00052 GO:0006082,GO:0006575,GO:0006732,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016053,GO:0019297,GO:0019298,GO:0019752,GO:0032787,GO:0042398,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 1.1.1.85 0.00000000000000001074 84.0
HFD3_k127_709664_2 phosphatase homologous to the C-terminal domain of histone macroH2A1 - - - 0.000000005384 58.0
HFD3_k127_7101047_0 Malate synthase K01638 - 2.3.3.9 1.524e-219 690.0
HFD3_k127_7101047_1 Catalyzes the reversible formation of glyoxylate and succinate from isocitrate K01637 - 4.1.3.1 2.601e-202 638.0
HFD3_k127_7102554_0 - - - - 0.0000000000000000000000000002122 116.0
HFD3_k127_7102554_1 MacB-like periplasmic core domain - - - 0.0000000000000000000004948 98.0
HFD3_k127_7102554_2 - - - - 0.000000002028 63.0
HFD3_k127_7108572_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 367.0
HFD3_k127_7108572_1 protein tyrosine phosphatase activity K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000000000000001499 194.0
HFD3_k127_7115651_0 Alpha-L-fucosidase K01206 - 3.2.1.51 2.168e-197 623.0
HFD3_k127_7115651_1 DNA-templated transcription, initiation - - - 0.000000000000000000000000000000000000000000000000003117 196.0
HFD3_k127_7115651_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000002014 179.0
HFD3_k127_7115651_3 Haem-binding domain - - - 0.000000000000000000000000000000000001486 144.0
HFD3_k127_7115651_4 TonB-dependent receptor - - - 0.0000000000000000000000000009502 116.0
HFD3_k127_7115651_5 Protein of unknown function (DUF3298) - - - 0.0000000001515 74.0
HFD3_k127_7116314_0 hydrolase activity, hydrolyzing O-glycosyl compounds K01176,K22253 - 3.2.1.1,3.2.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 428.0
HFD3_k127_7116314_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000001394 136.0
HFD3_k127_7116329_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 538.0
HFD3_k127_7116329_1 D-galactarate dehydratase Altronate K01685,K01708 - 4.2.1.42,4.2.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 392.0
HFD3_k127_7122859_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 547.0
HFD3_k127_7122859_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.0000000000000000000000000000000000000000000003147 169.0
HFD3_k127_712460_0 Voltage gated chloride channel K03281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 323.0
HFD3_k127_712460_1 - - - - 0.000000000000000001863 88.0
HFD3_k127_712460_2 bacterial OsmY and nodulation domain - - - 0.000000000000003656 85.0
HFD3_k127_712585_0 Fumarate hydratase (Fumerase) K01676 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002529 346.0
HFD3_k127_712585_1 - - - - 0.000000000002877 68.0
HFD3_k127_712585_2 Iron-containing redox enzyme - - - 0.00000003876 63.0
HFD3_k127_712585_3 - - - - 0.000001356 51.0
HFD3_k127_7126539_0 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 454.0
HFD3_k127_7126539_1 Sortilin, neurotensin receptor 3, - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 291.0
HFD3_k127_7126539_2 Endoribonuclease L-PSP - - - 0.0000000000000000000000000001902 119.0
HFD3_k127_7130046_0 histidine kinase A domain protein - - - 4.993e-232 738.0
HFD3_k127_7130046_1 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009217 411.0
HFD3_k127_7132090_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 377.0
HFD3_k127_7132090_1 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 343.0
HFD3_k127_7132090_2 plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000000003566 134.0
HFD3_k127_7132090_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000007962 122.0
HFD3_k127_7132090_4 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.000000000119 63.0
HFD3_k127_7144782_0 Dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 304.0
HFD3_k127_7144782_1 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007978 269.0
HFD3_k127_7145926_0 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001011 258.0
HFD3_k127_7145926_1 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.00000005506 64.0
HFD3_k127_7148123_0 Cytochrome c - - - 3.041e-308 957.0
HFD3_k127_7148123_1 long-chain fatty acid transporting porin activity - - - 2.824e-217 683.0
HFD3_k127_7148123_2 Transposase and inactivated derivatives, TnpA family - - - 0.000003296 50.0
HFD3_k127_7151655_0 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007323 315.0
HFD3_k127_7151655_1 Peptidase family C25 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001582 269.0
HFD3_k127_7151655_2 amine dehydrogenase activity K20276 - - 0.0000000000000000000000000000000000000000006106 177.0
HFD3_k127_7153730_0 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 422.0
HFD3_k127_7153730_1 Protein of unknown function DUF99 K09120 - - 0.000000000000000000000000000000000000000000000000000000000000000000006488 238.0
HFD3_k127_7153730_2 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000003133 243.0
HFD3_k127_7153730_3 Predicted nucleotidyltransferase K07074 - - 0.000000000000000002627 92.0
HFD3_k127_7154768_0 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000001055 211.0
HFD3_k127_7154768_1 Two component regulator propeller - - - 0.00000000000000000000000000000000003898 140.0
HFD3_k127_7154768_3 Domain of unknown function (DUF4157) - - - 0.000003829 57.0
HFD3_k127_7166240_0 cellulose binding K13735 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 464.0
HFD3_k127_7166240_1 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006435 341.0
HFD3_k127_7166240_3 PFAM Uncharacterised BCR, COG1649 - - - 0.00000000000000000000000000000001426 149.0
HFD3_k127_7166240_4 Fungalysin metallopeptidase (M36) - - - 0.0000005364 64.0
HFD3_k127_7166240_5 Probable zinc-ribbon domain - - - 0.00005706 49.0
HFD3_k127_7166265_0 Glycosyl transferase family 21 K11936 - - 5.497e-265 832.0
HFD3_k127_7166265_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 549.0
HFD3_k127_7166265_2 - K00262 - 1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 457.0
HFD3_k127_7166265_3 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000001507 162.0
HFD3_k127_7167278_0 Amidase K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 507.0
HFD3_k127_7167278_1 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000003565 160.0
HFD3_k127_7167278_2 Acid phosphatase homologues - - - 0.00000000000000000000000000000000003673 146.0
HFD3_k127_7167278_3 Glycosyltransferase family 87 - - - 0.000000000009643 77.0
HFD3_k127_7184301_0 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 297.0
HFD3_k127_7184301_1 Polysaccharide deacetylase - - - 0.00000000000000007252 85.0
HFD3_k127_7184301_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000007837 87.0
HFD3_k127_7186765_0 Putative esterase K07017 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 357.0
HFD3_k127_7186765_1 Domain of unknown function (DUF1877) - - - 0.000006774 55.0
HFD3_k127_7186765_2 Deacetylates O-acetyl-ADP ribose. Down-regulates ribonuclease 3 (RNase III) activity. Acts by interacting directly with the region of the ribonuclease that is required for dimerization activation - GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005515,GO:0008150,GO:0008428,GO:0009892,GO:0010605,GO:0016787,GO:0019213,GO:0019219,GO:0019222,GO:0019899,GO:0030234,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0043086,GO:0043900,GO:0044092,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0061463,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:1900190,GO:1900231 - 0.000007264 52.0
HFD3_k127_7187004_0 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000004566 177.0
HFD3_k127_7187004_1 amino acid activation for nonribosomal peptide biosynthetic process K03641,K20276 - - 0.0000000000000000000000000000000000009502 151.0
HFD3_k127_7188576_0 Esterase of the alpha-beta hydrolase superfamily - - - 0.0000000000000001812 94.0
HFD3_k127_7192095_0 Y_Y_Y domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 373.0
HFD3_k127_7192095_1 hydroperoxide reductase activity K01607 - 4.1.1.44 0.00000000000000000000000000008603 117.0
HFD3_k127_7192095_2 - - - - 0.0000000000003236 69.0
HFD3_k127_7192841_0 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000000000001944 227.0
HFD3_k127_7192841_1 Sulfatase K01133 - 3.1.6.6 0.0000000000000000000000001087 117.0
HFD3_k127_7192841_2 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000002678 104.0
HFD3_k127_7195073_0 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 0.00000000000000000000009399 113.0
HFD3_k127_7195073_1 Cytochrome c - - - 0.0000008475 53.0
HFD3_k127_7196388_0 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 434.0
HFD3_k127_7196388_1 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.00000000000000000000000003366 117.0
HFD3_k127_7196388_2 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.00000000000002652 82.0
HFD3_k127_7197974_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 311.0
HFD3_k127_7197974_1 BadF BadG BcrA BcrD type - - - 0.00000000000000000000000000000000000000000000000002765 192.0
HFD3_k127_7197974_2 Y_Y_Y domain K11527 - 2.7.13.3 0.000000000000000000000000000000000003279 154.0
HFD3_k127_7201660_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 9.721e-264 831.0
HFD3_k127_7208596_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000001412 224.0
HFD3_k127_7208596_1 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000001626 196.0
HFD3_k127_7217915_0 Domain of unknown function (DUF4118) - - - 0.0000000000000000000000000000000000000000000000000001338 206.0
HFD3_k127_7222018_0 Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 406.0
HFD3_k127_7222018_1 cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005691 286.0
HFD3_k127_7222018_2 Outer membrane efflux protein - - - 0.0000000000000000000006605 99.0
HFD3_k127_722367_0 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 485.0
HFD3_k127_722367_1 Glycosyl transferase family group 2 - - - 0.0000000002079 64.0
HFD3_k127_7232131_0 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000009157 104.0
HFD3_k127_7232131_1 Putative prokaryotic signal transducing protein - - - 0.00000000000000000000001287 107.0
HFD3_k127_7232131_2 - - - - 0.00002453 55.0
HFD3_k127_7233059_0 peptidase - - - 8.67e-243 757.0
HFD3_k127_7233059_1 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000183 238.0
HFD3_k127_7233059_2 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001684 223.0
HFD3_k127_7233059_3 3-demethylubiquinone-9 3-methyltransferase K04750 - - 0.0000000000000000000000000000000000000000000000000000000000000005735 222.0
HFD3_k127_7233059_4 membrane protein (DUF2306) - - - 0.0000000000000000000000000000000000000000000000000000002532 202.0
HFD3_k127_7233059_5 PFAM DoxX family protein K15977 - - 0.0000000000000000000000000000000001682 136.0
HFD3_k127_7233059_6 acetyltransferase K18816 - 2.3.1.82 0.0000000000000000000000000000000006283 134.0
HFD3_k127_7233059_7 YCII-related domain - - - 0.0000000000000000000004974 95.0
HFD3_k127_7233059_8 - - - - 0.000000000000007514 82.0
HFD3_k127_7235191_0 Hep Hag repeat protein - - - 0.00000000000000001422 94.0
HFD3_k127_7235191_1 Chaperone of endosialidase - - - 0.000009347 56.0
HFD3_k127_723824_0 PFAM SAICAR synthetase K01923,K13713 - 6.3.2.6,6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 405.0
HFD3_k127_723824_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006661 266.0
HFD3_k127_723866_0 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000003076 188.0
HFD3_k127_723866_1 Transposase, Mutator family - - - 0.0000000001004 63.0
HFD3_k127_723866_2 DNA-templated transcription, initiation K02405 - - 0.0000893 47.0
HFD3_k127_724203_0 metal ion transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 544.0
HFD3_k127_724203_1 PFAM Universal stress protein family - - - 0.0000000004463 62.0
HFD3_k127_7245778_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 454.0
HFD3_k127_7245778_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007782 450.0
HFD3_k127_7245778_2 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00003947 48.0
HFD3_k127_7248312_0 Histidine kinase - - - 0.00000000000000004357 91.0
HFD3_k127_7248312_1 TonB dependent receptor - - - 0.0002221 53.0
HFD3_k127_7262285_0 efflux transmembrane transporter activity - - - 2.373e-209 677.0
HFD3_k127_7262285_1 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 632.0
HFD3_k127_7262285_2 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003845 317.0
HFD3_k127_7262285_3 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000192 135.0
HFD3_k127_7282027_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.259e-221 698.0
HFD3_k127_7282027_1 Ankyrin repeat - - - 0.0000000000000000000000000452 120.0
HFD3_k127_7282027_2 Peptidase, M56 - - - 0.000000000009486 74.0
HFD3_k127_7282027_3 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000106 62.0
HFD3_k127_7289752_0 Carboxypeptidase regulatory-like domain - - - 2.62e-261 831.0
HFD3_k127_7289974_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 2.208e-225 712.0
HFD3_k127_7289974_1 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 357.0
HFD3_k127_7289974_2 PFAM YdjC family protein K03478 - 3.5.1.105 0.0000000000000000000000000000000000003209 146.0
HFD3_k127_7292986_0 Belongs to the proline racemase family K12658 GO:0003674,GO:0003824,GO:0016853,GO:0016854,GO:0016855,GO:0036361,GO:0047580,GO:0047661 5.1.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 441.0
HFD3_k127_7292986_1 FAD dependent oxidoreductase K00303,K21061 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008481 443.0
HFD3_k127_7292986_2 2Fe-2S iron-sulfur cluster binding domain K00302 - 1.5.3.1 0.00000000000000000006187 91.0
HFD3_k127_7293693_0 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 476.0
HFD3_k127_7293693_1 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000005628 204.0
HFD3_k127_7297358_0 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000009214 220.0
HFD3_k127_7297358_1 - - - - 0.00000000000000000000000002838 111.0
HFD3_k127_7300241_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 3.234e-221 702.0
HFD3_k127_7300241_1 Polyprenyl synthetase K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 317.0
HFD3_k127_7300241_2 phosphoesterases, related to the Icc protein - - - 0.000000000000000000000000007513 113.0
HFD3_k127_7300241_3 Dimerisation domain - - - 0.0000000000000000000000000189 111.0
HFD3_k127_7300241_4 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000005864 80.0
HFD3_k127_7301894_0 COG0208 Ribonucleotide reductase, beta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006995 496.0
HFD3_k127_7301894_1 Dehydrogenase K00114,K17760,K22473 - 1.1.2.8,1.1.5.5,1.1.9.1 0.000000000000000000000000000000000000000000000000004513 186.0
HFD3_k127_7301894_2 Zn-dependent dipeptidase, microsomal dipeptidase - - - 0.0000000000000000000000000000000000000000000000002908 179.0
HFD3_k127_7301894_3 Caspase domain - - - 0.00000000000000001759 95.0
HFD3_k127_7303376_0 Alpha-2-Macroglobulin K06894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002286 311.0
HFD3_k127_731362_0 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006253 335.0
HFD3_k127_731362_1 Fimbrial assembly protein (PilN) K02663 - - 0.0001485 52.0
HFD3_k127_7320818_0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.00000000000000000000000000000000000000000000000000000001312 208.0
HFD3_k127_7322202_0 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000001552 221.0
HFD3_k127_7322202_1 glycerophosphodiester phosphodiesterase activity K01126 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008081,GO:0008889,GO:0009279,GO:0016020,GO:0016787,GO:0016788,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044462,GO:0044464,GO:0046872,GO:0071944 3.1.4.46 0.0000000000000000000000000000000000000000000003123 181.0
HFD3_k127_7322202_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00363,K05710 - 1.7.1.15 0.00000000000000000000002136 103.0
HFD3_k127_732549_0 N-Acetylmuramoyl-L-alanine amidase K03806 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000007262 225.0
HFD3_k127_732549_1 - - - - 0.000000000000000000000000002128 119.0
HFD3_k127_732549_2 Caspase domain - - - 0.00000000000000000000001133 112.0
HFD3_k127_7326694_0 helix_turn_helix, Lux Regulon K02282,K07689 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001422 259.0
HFD3_k127_7326694_1 PAC sensor signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001963 252.0
HFD3_k127_7326694_2 lipolytic protein G-D-S-L family - - - 0.000000000000000000003341 97.0
HFD3_k127_7328392_0 Belongs to the PdxS SNZ family K06215 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 434.0
HFD3_k127_7328392_1 phenazine biosynthesis protein PhzF family K06998 - 5.3.3.17 0.000000000000000000000000000000000002347 145.0
HFD3_k127_7328988_0 COG0666 FOG Ankyrin repeat K06867 - - 0.0000000000000000000000000000000000000000000000000000000001282 218.0
HFD3_k127_7329064_0 glutamate--cysteine ligase - - - 1.247e-231 733.0
HFD3_k127_7329064_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 479.0
HFD3_k127_7329064_2 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008058 407.0
HFD3_k127_7329064_3 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 GO:0000302,GO:0001101,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0016672,GO:0016675,GO:0019538,GO:0030091,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0043546,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0048037,GO:0050662,GO:0050896,GO:0055114,GO:0071704,GO:0097159,GO:1901363,GO:1901530,GO:1901564,GO:1901700 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009802 392.0
HFD3_k127_7329064_4 Cys-tRNA(Pro) hydrolase activity K03976 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0043906,GO:0043907,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000008244 216.0
HFD3_k127_7329064_5 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000000021 195.0
HFD3_k127_7329064_6 Protein of unknown function (DUF1223) - - - 0.00000000000000005566 87.0
HFD3_k127_7333090_0 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000774 165.0
HFD3_k127_7333090_1 Peptidase family C25 - - - 0.000000000000000000000002605 115.0
HFD3_k127_7333090_2 - - - - 0.000000000001504 68.0
HFD3_k127_7333090_3 - - - - 0.000000000505 61.0
HFD3_k127_7336929_0 amine oxidase K00276 - 1.4.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 314.0
HFD3_k127_7336929_1 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 297.0
HFD3_k127_7336929_2 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.0000000000000000000000000000000006486 144.0
HFD3_k127_7336929_3 Trm112p-like protein K09791 - - 0.00000000000000000002984 92.0
HFD3_k127_7340690_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 616.0
HFD3_k127_7340690_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001602 282.0
HFD3_k127_7342795_0 B-1 B cell differentiation - - - 0.00000000000000000000000000000000000000000000000000000000000000001266 247.0
HFD3_k127_7348749_0 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008144,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015399,GO:0015405,GO:0015407,GO:0015591,GO:0015608,GO:0015611,GO:0015749,GO:0015750,GO:0015752,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034219,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043211,GO:0043492,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 462.0
HFD3_k127_7354568_0 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 373.0
HFD3_k127_7354568_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008469 320.0
HFD3_k127_7354568_2 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000003472 159.0
HFD3_k127_7357878_0 POT family K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004541 435.0
HFD3_k127_7357878_1 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000000000000000005847 181.0
HFD3_k127_7357878_2 SnoaL-like domain - - - 0.00000000000000009056 87.0
HFD3_k127_7357878_3 Beta-lactamase - - - 0.0000000006915 65.0
HFD3_k127_7357947_0 56kDa selenium binding protein (SBP56) K17285 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 486.0
HFD3_k127_7357947_1 Tetratricopeptide repeat - - - 0.000000000000000000000000001445 126.0
HFD3_k127_7357947_2 diacylglycerol kinase, catalytic region - - - 0.0000000000001432 78.0
HFD3_k127_7362657_0 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 511.0
HFD3_k127_7362657_1 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004997 293.0
HFD3_k127_7362657_2 transferase activity, transferring acyl groups - - - 0.000000000000000000000000000000007544 129.0
HFD3_k127_7362956_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008872 619.0
HFD3_k127_7362956_1 Predicted methyltransferase regulatory domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 369.0
HFD3_k127_7362956_2 Heparinase II/III N-terminus - - - 0.000000000000000000000000000000000000000000000000000000234 207.0
HFD3_k127_7362956_3 Polysaccharide biosynthesis C-terminal domain - - - 0.000000000000000000000000004734 125.0
HFD3_k127_7371594_0 Unusual protein kinase - - - 3.553e-200 639.0
HFD3_k127_7371594_1 - - - - 0.00000000000000000000000000000000000000000000000001269 188.0
HFD3_k127_7373044_0 ADP-heptose-lipopolysaccharide heptosyltransferase activity - - - 0.00000000000000000000000000000000000407 149.0
HFD3_k127_7373044_1 Proline dehydrogenase K00318 - - 0.00000000000004111 75.0
HFD3_k127_7373144_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 4.332e-233 749.0
HFD3_k127_7373144_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000004628 175.0
HFD3_k127_7387569_0 Putative cyclase K07130 - 3.5.1.9 0.00000000000000000000000000000000000000000000000000000003199 202.0
HFD3_k127_7387569_1 PFAM KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000000000000000000000271 136.0
HFD3_k127_7388026_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 534.0
HFD3_k127_7388026_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000007473 240.0
HFD3_k127_7388026_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000306 203.0
HFD3_k127_7388026_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000006623 106.0
HFD3_k127_738903_0 AlkA N-terminal domain K13529,K13530 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 513.0
HFD3_k127_738903_1 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 410.0
HFD3_k127_738903_2 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000621 224.0
HFD3_k127_738903_3 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000001205 183.0
HFD3_k127_738903_4 YjbR - - - 0.0000000000000000000000000002217 119.0
HFD3_k127_738911_0 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 588.0
HFD3_k127_738911_1 TPM domain K06872 - - 0.000000000000000000000002928 113.0
HFD3_k127_738911_2 TPM domain K06872 - - 0.00000000009958 71.0
HFD3_k127_7392904_0 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 578.0
HFD3_k127_7392904_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000001978 218.0
HFD3_k127_7392904_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 0.000000000000000000000000000000000000003213 163.0
HFD3_k127_7392904_3 Zn-dependent proteases and their inactivated homologs K03592 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 0.000000000003095 73.0
HFD3_k127_7401384_0 Carboxypeptidase regulatory-like domain - - - 1.644e-256 812.0
HFD3_k127_7407557_0 Xylose isomerase-like TIM barrel K01816 - 5.3.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 359.0
HFD3_k127_7407557_1 Belongs to the glycosyl hydrolase 13 family K07214 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 325.0
HFD3_k127_7410124_0 serine-type peptidase activity - - - 1.179e-288 906.0
HFD3_k127_7410124_1 Serves to protect cells from the toxic effects of hydrogen peroxide K03781 - 1.11.1.6 5.484e-275 851.0
HFD3_k127_7426591_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000001376 153.0
HFD3_k127_7426591_1 Phosphoribosyl transferase domain K00762 - 2.4.2.10 0.00000000000000000000000000009967 119.0
HFD3_k127_7426591_2 Universal stress protein family - - - 0.000000000000001154 83.0
HFD3_k127_7426591_3 - - - - 0.00000009592 61.0
HFD3_k127_7435075_0 Serine aminopeptidase, S33 K01048 GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016740,GO:0016746,GO:0016747,GO:0016787,GO:0016788,GO:0044238,GO:0044464,GO:0052689,GO:0071704,GO:0071944 3.1.1.5 0.000000000000000000000000000000000000000000000000000003407 201.0
HFD3_k127_7435075_1 - - - - 0.000003571 52.0
HFD3_k127_7437933_0 Rhodanese Homology Domain - - - 0.0000000000000000000000000000003922 127.0
HFD3_k127_7438982_0 Esterase PHB depolymerase K03932 - - 0.000000000000000009251 96.0
HFD3_k127_7438982_1 Autotransporter beta-domain - - - 0.000000000000009124 87.0
HFD3_k127_7441300_0 S-layer homology domain K17734 - - 0.0000000000000000000000000000000000000000000000002491 194.0
HFD3_k127_7441542_0 ATPase activity K02045 - 3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009358 348.0
HFD3_k127_7441542_1 phosphate-selective porin O and P K07221 - - 0.0000000000000000000000000000000000000000000000001645 194.0
HFD3_k127_7453332_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 503.0
HFD3_k127_7453332_1 Belongs to the multicopper oxidase YfiH RL5 family K05810 GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0046983,GO:0055114 - 0.000000000182 67.0
HFD3_k127_7455379_0 TIGRFAM outer membrane protein assembly complex, YaeT protein K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 379.0
HFD3_k127_7456549_0 COG3209 Rhs family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 302.0
HFD3_k127_7456549_1 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009575 297.0
HFD3_k127_7456549_2 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000001616 197.0
HFD3_k127_7456957_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 324.0
HFD3_k127_7456957_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001235 257.0
HFD3_k127_7456957_2 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002604 246.0
HFD3_k127_7456957_3 - - - - 0.0000000000000000000000000000000486 141.0
HFD3_k127_7462529_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000001839 96.0
HFD3_k127_7462529_1 Peptidoglycan-binding domain 1 protein - - - 0.00001021 56.0
HFD3_k127_7467582_0 Cadherin repeats. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009315 467.0
HFD3_k127_7467582_1 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.0000000000000000000000001315 119.0
HFD3_k127_7467582_2 Lipopolysaccharide-assembly - - - 0.0000000000000000000001663 103.0
HFD3_k127_7467582_3 Binds directly to 16S ribosomal RNA K02968 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000001125 66.0
HFD3_k127_7470277_0 Lamin Tail Domain K07004 - - 8.818e-240 779.0
HFD3_k127_7470861_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 570.0
HFD3_k127_7470861_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005013 386.0
HFD3_k127_7474311_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 316.0
HFD3_k127_7474311_1 Belongs to the aldehyde dehydrogenase family K22187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 308.0
HFD3_k127_7478610_0 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000003184 140.0
HFD3_k127_7478610_1 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.00000000000000000000000000006226 120.0
HFD3_k127_7481401_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000009762 180.0
HFD3_k127_7481401_1 radical SAM domain protein - - - 0.000000000000002531 81.0
HFD3_k127_7481401_2 Glycosyltransferase like family 2 - - - 0.0001173 53.0
HFD3_k127_7486118_0 PFAM monooxygenase FAD-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 349.0
HFD3_k127_7486118_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000007869 231.0
HFD3_k127_7486118_2 heat shock protein 70 K04043,K04044 - - 0.000000000000000000000000000000000000000000000000000000000000003657 223.0
HFD3_k127_7486118_3 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.00000000000000000000000000000000001623 139.0
HFD3_k127_7486118_4 FeS assembly protein IscX - - - 0.000000000000000000000000001916 112.0
HFD3_k127_7486573_0 Glycosyltransferase family 28 N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 458.0
HFD3_k127_7486573_1 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 306.0
HFD3_k127_7486573_2 Domain of unknown function (DUF4136) - - - 0.0000006716 54.0
HFD3_k127_7487169_0 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 371.0
HFD3_k127_7490436_0 e3 binding domain K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008291 317.0
HFD3_k127_7499352_0 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000000000000009395 213.0
HFD3_k127_7499352_1 Peptidase family C25 - - - 0.0000000000000000000000000000000000000000000000000000000006252 222.0
HFD3_k127_7499352_2 Sortilin, neurotensin receptor 3, - - - 0.00000000000000000000000000000000000000000000002472 175.0
HFD3_k127_7502450_0 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 413.0
HFD3_k127_7502450_1 LVIVD repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001703 263.0
HFD3_k127_7502450_2 hyperosmotic response K04065 - - 0.0000002343 60.0
HFD3_k127_7505234_0 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 422.0
HFD3_k127_7505234_1 integral membrane protein - - - 0.00000000000004429 83.0
HFD3_k127_7505342_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000001951 268.0
HFD3_k127_7505342_1 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000008187 188.0
HFD3_k127_7505342_2 PFAM adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000299 62.0
HFD3_k127_7507565_0 PFAM Pyrrolo-quinoline quinone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000585 267.0
HFD3_k127_7507565_1 4-Hydroxyphenylpyruvate dioxygenase K00406,K05606,K17315 - 5.1.99.1 0.00000001873 62.0
HFD3_k127_7508904_0 Caspase domain - - - 0.00000000000000000000000000003213 120.0
HFD3_k127_7508904_1 ECF sigma factor - - - 0.0000000000000000000003735 100.0
HFD3_k127_7508904_2 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000006359 96.0
HFD3_k127_7508904_3 ECF sigma factor - - - 0.00000000000000003007 83.0
HFD3_k127_7508904_5 - - - - 0.000000003494 63.0
HFD3_k127_7512818_0 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 486.0
HFD3_k127_7512818_1 Phosphoesterase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000963 459.0
HFD3_k127_7516806_0 amino acid - - - 1.68e-263 826.0
HFD3_k127_7516806_1 Hydroxymethylglutaryl-coenzyme A reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 475.0
HFD3_k127_7516806_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002857 273.0
HFD3_k127_7516806_3 CYTH domain - - - 0.0000000000000000000000000000000000000000001366 164.0
HFD3_k127_7518439_0 Magnesium chelatase subunit H K03403 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 437.0
HFD3_k127_7521416_0 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009366 465.0
HFD3_k127_7521416_1 Transcriptional regulatory protein, C terminal K07665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004988 327.0
HFD3_k127_7521416_2 protein histidine kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008823 308.0
HFD3_k127_7521416_3 Peptidase family S51 K05995 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.13.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003659 287.0
HFD3_k127_7521416_4 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000007628 247.0
HFD3_k127_7521416_5 Penicillinase repressor - - - 0.000000000000000000001895 100.0
HFD3_k127_7521674_0 electron transfer activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 524.0
HFD3_k127_7521674_1 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 440.0
HFD3_k127_7521674_2 cAMP biosynthetic process - - - 0.000000000000006703 78.0
HFD3_k127_7523686_0 Oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001008 271.0
HFD3_k127_7523686_1 Domain of unknown function (DU1801) - - - 0.00000000000000001139 87.0
HFD3_k127_7523686_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00004604 56.0
HFD3_k127_7529417_0 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 379.0
HFD3_k127_7529417_1 Amidinotransferase K01482 - 3.5.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006562 282.0
HFD3_k127_7529417_2 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.000000000000000000000000000000000000000000000000000000000000000000000000006458 259.0
HFD3_k127_7529417_3 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000001786 229.0
HFD3_k127_7529417_4 Cupin domain - - - 0.0000000000000000000000000000000000000000000001279 171.0
HFD3_k127_7529417_5 Domain of unknown function (DUF1844) - - - 0.00000004064 62.0
HFD3_k127_7532554_0 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 620.0
HFD3_k127_7532554_1 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004483 506.0
HFD3_k127_7532554_2 DegT/DnrJ/EryC1/StrS aminotransferase family K13010 - 2.6.1.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 440.0
HFD3_k127_7532554_3 Bacterial sugar transferase - - - 0.0000000000000000000000000000000000000000000002072 176.0
HFD3_k127_7532554_4 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.0000000000000000000000000000000000000000000002217 173.0
HFD3_k127_7532554_5 Transglutaminase-like superfamily - - - 0.0000000000000000000000002831 110.0
HFD3_k127_7532554_6 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000000000000000000002299 96.0
HFD3_k127_7533874_0 Domain of unknown function (DUF5009) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 400.0
HFD3_k127_7533874_1 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 328.0
HFD3_k127_7533874_2 - - - - 0.000000000000005674 78.0
HFD3_k127_754260_0 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000002165 114.0
HFD3_k127_7545335_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000136 90.0
HFD3_k127_7549314_0 Radical SAM - - - 8.981e-305 937.0
HFD3_k127_7549314_1 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005699 469.0
HFD3_k127_7552646_0 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 449.0
HFD3_k127_7552646_1 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000002408 205.0
HFD3_k127_7552680_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 2.294e-213 671.0
HFD3_k127_7555417_0 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 590.0
HFD3_k127_7555417_1 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 434.0
HFD3_k127_7561466_0 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000004025 215.0
HFD3_k127_7561466_1 Hep Hag repeat protein K11904,K21449 - - 0.0000000000000000000001346 105.0
HFD3_k127_7563456_0 Ribonuclease HII K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000001205 198.0
HFD3_k127_7563456_1 ATP-dependent protease La (LON) substrate-binding domain K01338,K07157 - 3.4.21.53 0.00000000000000000007381 94.0
HFD3_k127_7564541_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 413.0
HFD3_k127_756543_0 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006551 270.0
HFD3_k127_756543_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000007293 252.0
HFD3_k127_756543_2 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00000000000000000000000000000000000000000000000000000000001257 217.0
HFD3_k127_756543_3 - - - - 0.00000000000000000000000000000000001743 147.0
HFD3_k127_756543_4 Transcriptional regulatory protein, C terminal K07658 - - 0.00000000000000000001116 96.0
HFD3_k127_7576969_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 497.0
HFD3_k127_7576969_1 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009644 279.0
HFD3_k127_7584183_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001355 253.0
HFD3_k127_7584183_1 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000003821 192.0
HFD3_k127_7591018_0 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000576 256.0
HFD3_k127_7591018_1 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000001398 140.0
HFD3_k127_7591018_2 Heat shock 70 kDa protein K04043 - - 0.000000000000000000000002348 102.0
HFD3_k127_7591018_3 signal peptide processing K03100 - 3.4.21.89 0.000000007407 57.0
HFD3_k127_7592849_0 Cytochrome c K08685 - 1.4.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007192 443.0
HFD3_k127_7592849_1 Trehalose utilisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 364.0
HFD3_k127_7592849_2 Cytochrome c K08685 - 1.4.9.1 0.00000000000000000000000000000000000000004473 155.0
HFD3_k127_7592849_3 Beta-lactamase - - - 0.0000000000003364 83.0
HFD3_k127_7596606_0 PFAM amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007443 426.0
HFD3_k127_7596606_1 Armadillo/beta-catenin-like repeats - - - 0.00000001552 59.0
HFD3_k127_7599127_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.494e-230 724.0
HFD3_k127_7599127_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001978 284.0
HFD3_k127_7599127_2 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000000108 201.0
HFD3_k127_7602228_0 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 380.0
HFD3_k127_7602228_1 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000000006812 214.0
HFD3_k127_7606046_0 Histidine kinase K02480,K07683 - 2.7.13.3 1.892e-258 829.0
HFD3_k127_7606046_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000007974 222.0
HFD3_k127_760665_0 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 9.554e-229 733.0
HFD3_k127_760665_1 COGs COG1432 conserved - - - 0.00000000000000000000000000000000001983 143.0
HFD3_k127_7607137_0 - - - - 0.0000000000000000000000000002239 130.0
HFD3_k127_7607137_1 - - - - 0.0000000208 64.0
HFD3_k127_7613850_0 TonB-dependent Receptor Plug Domain - - - 7.479e-198 643.0
HFD3_k127_7618778_0 cytochrome c peroxidase K00428 - 1.11.1.5 2.148e-223 715.0
HFD3_k127_7618778_1 Domains in Na-Ca exchangers and integrin-beta4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001254 255.0
HFD3_k127_7618778_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000002366 53.0
HFD3_k127_7620253_0 peptidase - - - 0.0000000000000000000000000000000000000000002471 166.0
HFD3_k127_7620253_1 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000002414 160.0
HFD3_k127_7621860_0 Phage late control gene D protein (GPD) K11904 - - 0.000000000000000000000000000000000000000000000000000000000000003816 223.0
HFD3_k127_7621860_1 TPR repeat - - - 0.000000000000000601 90.0
HFD3_k127_7624422_0 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 376.0
HFD3_k127_7624422_1 Histidine kinase - - - 0.00000000000000000000001474 100.0
HFD3_k127_7624440_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 569.0
HFD3_k127_7624440_1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000008919 237.0
HFD3_k127_7624440_2 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000001884 221.0
HFD3_k127_7626582_0 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 452.0
HFD3_k127_7626582_1 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 319.0
HFD3_k127_7626582_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000007918 230.0
HFD3_k127_7637830_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 597.0
HFD3_k127_7637830_1 Methane oxygenase PmoA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 413.0
HFD3_k127_7637830_2 Oxidoreductase NAD-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001433 286.0
HFD3_k127_7641851_0 TIGRFAM type VI secretion protein, VC_A0110 family K11896 - - 8.615e-202 646.0
HFD3_k127_7641851_1 Predicted methyltransferase regulatory domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 344.0
HFD3_k127_7641851_2 type VI secretion protein, VC_A0111 family K11895 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004745 304.0
HFD3_k127_7641851_3 C-terminal, D2-small domain, of ClpB protein K11907 - - 0.0000000000000000000000000000000000000000000000000000000000002835 216.0
HFD3_k127_7641851_4 Murein transglycosylase - - - 0.000000000002725 77.0
HFD3_k127_7642434_0 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000001721 169.0
HFD3_k127_7642434_1 Belongs to the UPF0235 family K09131 - - 0.0000000000000000000006205 98.0
HFD3_k127_7642434_2 YGGT family K02221 - - 0.00000003094 61.0
HFD3_k127_7644900_0 Protein of unknown function (DUF1326) - - - 0.00000000000000000000000000000000000000000000000000000000000003709 222.0
HFD3_k127_7644900_1 O-Antigen ligase K02847 - - 0.00000000000000000000001561 111.0
HFD3_k127_7648194_0 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000249 229.0
HFD3_k127_764884_0 PFAM O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 329.0
HFD3_k127_764884_1 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000001198 216.0
HFD3_k127_764927_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 494.0
HFD3_k127_7655101_0 gluconolactonase activity K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003747 599.0
HFD3_k127_7655101_1 Cupin 2, conserved barrel domain protein K11477 - - 0.00000000000000000000000000000000000018 143.0
HFD3_k127_7655101_2 Haem-degrading K11477 - - 0.00000000000000000000000000000005165 131.0
HFD3_k127_7655949_0 WD40-like Beta Propeller Repeat - - - 1.989e-253 792.0
HFD3_k127_7655949_1 Cys/Met metabolism PLP-dependent enzyme K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005168 561.0
HFD3_k127_7655949_2 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 301.0
HFD3_k127_7655949_3 peptidase S9 prolyl oligopeptidase active site K01278 - 3.4.14.5 0.0000000000000000000000000000000000000000000000004162 183.0
HFD3_k127_7664369_0 Carboxypeptidase regulatory-like domain - - - 5.73e-322 1020.0
HFD3_k127_7664369_1 beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000001001 225.0
HFD3_k127_7669864_0 cAMP biosynthetic process K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007464 304.0
HFD3_k127_7669864_1 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000001001 138.0
HFD3_k127_7679465_0 PFAM Amidohydrolase 2 K07046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005348 342.0
HFD3_k127_7679465_1 dehydrogenase reductase K18333 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 327.0
HFD3_k127_7679465_2 L-rhamnose mutarotase K03534 - 5.1.3.32 0.000000000000000000000000000000000000000004546 160.0
HFD3_k127_7683593_0 galactose-6-phosphate isomerase activity K00761,K01808 - 2.4.2.9,5.3.1.6 0.00000000000000000000000000000000000000000003702 169.0
HFD3_k127_7683593_1 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000001232 147.0
HFD3_k127_7683593_2 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000001409 60.0
HFD3_k127_7694842_0 CarboxypepD_reg-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 460.0
HFD3_k127_7697770_0 Zinc carboxypeptidase - - - 5.891e-239 765.0
HFD3_k127_7697770_1 aminopeptidase - - - 2.465e-215 683.0
HFD3_k127_7697770_2 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.0000000000000000000000000004987 117.0
HFD3_k127_7697770_3 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.0000000000000000000009181 101.0
HFD3_k127_7705069_0 PFAM beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004681 501.0
HFD3_k127_7705069_1 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000008598 167.0
HFD3_k127_7706017_0 SPTR Tetratricopeptide repeat domain protein - - - 7.708e-217 709.0
HFD3_k127_7706017_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001272 250.0
HFD3_k127_7706017_2 DNA-templated transcription, initiation K03088 - - 0.000955 49.0
HFD3_k127_7707036_0 Peptidase family C25 - - - 0.0000000000000003757 84.0
HFD3_k127_7707036_1 4 iron, 4 sulfur cluster binding - - - 0.00000000001306 68.0
HFD3_k127_7707408_0 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004018 257.0
HFD3_k127_7707408_1 TOBE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000471 239.0
HFD3_k127_7707408_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000006107 199.0
HFD3_k127_7707408_3 Thioredoxin-like K02199 - - 0.000000000000000000000000001031 118.0
HFD3_k127_7707408_4 Protein involved in meta-pathway of phenol degradation - - - 0.00001791 49.0
HFD3_k127_7707408_5 ABC transporter, permease protein K02053,K11070 - - 0.00002705 49.0
HFD3_k127_7708686_0 DNA integration - - - 0.00000000000002189 78.0
HFD3_k127_7710467_0 Peptidase family C25 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000477 323.0
HFD3_k127_7710467_1 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001677 287.0
HFD3_k127_7710467_2 WD40 domain protein beta Propeller - - - 0.000000000000000000000000000000000000000000000000000000000204 228.0
HFD3_k127_7710467_3 Protein of unknown function (DUF418) K07148 - - 0.00000000000000002466 84.0
HFD3_k127_7710467_6 Belongs to the glycosyl hydrolase 26 family - - - 0.00001475 58.0
HFD3_k127_7722872_0 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000005922 177.0
HFD3_k127_7730928_0 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 377.0
HFD3_k127_7730928_1 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004705 370.0
HFD3_k127_7732940_0 PFAM helix-turn-helix- domain containing protein AraC type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004389 262.0
HFD3_k127_7738967_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 1.186e-198 631.0
HFD3_k127_7738967_1 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007086 511.0
HFD3_k127_7738967_2 DoxX-like family - - - 0.00000000000000000000000000000000002539 141.0
HFD3_k127_7738967_3 Zn peptidase - - - 0.0002404 51.0
HFD3_k127_7740771_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 566.0
HFD3_k127_7740771_1 Uncharacterized conserved protein (DUF2196) - - - 0.00000000000000000000003767 101.0
HFD3_k127_7743202_0 Tricorn protease PDZ domain K08676 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 611.0
HFD3_k127_777153_0 PBS lyase HEAT-like repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 554.0
HFD3_k127_777153_1 Methyltransferase, chemotaxis proteins K00575,K13486 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 287.0
HFD3_k127_784391_0 hydrolase, family 65, central catalytic K15923 - 3.2.1.51 1.35e-230 728.0
HFD3_k127_786310_0 - - - - 0.00000000000000000000000000000000000000000000001732 180.0
HFD3_k127_786310_1 Pregnancy-associated plasma protein-A - - - 0.000000000000000000000000000000000000002854 161.0
HFD3_k127_786310_2 Hep Hag repeat protein K11904,K21449 - - 0.0000000000000000007561 96.0
HFD3_k127_786426_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 331.0
HFD3_k127_789509_0 Belongs to the K00958,K13811 - 2.7.1.25,2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000003656 258.0
HFD3_k127_789509_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000003936 237.0
HFD3_k127_789509_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000001431 229.0
HFD3_k127_789509_3 Bacterial membrane protein, YfhO - - - 0.000000000000000007041 97.0
HFD3_k127_789509_4 amino acid K03294 - - 0.000000000003587 68.0
HFD3_k127_790552_0 ASPIC and UnbV - - - 2.078e-231 724.0
HFD3_k127_790552_1 peptidyl-tyrosine sulfation - - - 0.000007344 53.0
HFD3_k127_791217_0 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 325.0
HFD3_k127_791217_1 Protein of unknown function (DUF421) - - - 0.000000000000000000000000000000000000000000000000000000000000009672 221.0
HFD3_k127_791217_2 Uncharacterized conserved protein (DUF2164) - - - 0.000000000000000000000000000001029 125.0
HFD3_k127_800998_0 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 351.0
HFD3_k127_800998_1 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000002553 211.0
HFD3_k127_803919_0 FAE1/Type III polyketide synthase-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004855 326.0
HFD3_k127_803919_1 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001131 274.0
HFD3_k127_803919_2 - - - - 0.00000000000000000000000000000003001 134.0
HFD3_k127_803919_3 peptidyl-tyrosine sulfation - - - 0.000000002329 60.0
HFD3_k127_806638_0 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000000001004 145.0
HFD3_k127_806638_1 Periplasmic component of the Tol biopolymer transport system - - - 0.000000000000000003929 98.0
HFD3_k127_806965_0 Protein of unknown function (DUF4243) - - - 0.000000000000000000000000000000000000000000000000001059 198.0
HFD3_k127_806965_1 PQQ-like domain - - - 0.000000002 64.0
HFD3_k127_811507_0 Protein of unknown function (DUF1553) - - - 7.964e-251 795.0
HFD3_k127_812307_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 395.0
HFD3_k127_812307_1 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 353.0
HFD3_k127_819250_0 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 352.0
HFD3_k127_819250_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000001503 126.0
HFD3_k127_81943_0 deaminase zinc-binding - - - 0.00000000000000000000000000000000000000000007691 164.0
HFD3_k127_81943_1 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000004262 164.0
HFD3_k127_81943_2 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000000001112 132.0
HFD3_k127_81943_3 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000001177 121.0
HFD3_k127_824596_0 Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons K01563 - 3.8.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003599 421.0
HFD3_k127_824596_1 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000007022 78.0
HFD3_k127_825729_0 Zinc metalloprotease (Elastase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 427.0
HFD3_k127_825729_1 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000162 190.0
HFD3_k127_826588_0 Periplasmic binding protein LacI transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005623 399.0
HFD3_k127_826588_1 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003204 255.0
HFD3_k127_826588_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000001991 222.0
HFD3_k127_830794_0 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 3.138e-208 659.0
HFD3_k127_830794_1 Tetratricopeptide repeat - - - 0.00000000000000000003796 105.0
HFD3_k127_830794_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000001455 62.0
HFD3_k127_837558_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 324.0
HFD3_k127_837558_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000001267 115.0
HFD3_k127_838238_0 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000003989 224.0
HFD3_k127_838238_1 - - - - 0.0000001062 57.0
HFD3_k127_841157_0 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000007562 161.0
HFD3_k127_841157_1 Protein tyrosine kinase - - - 0.00000005286 63.0
HFD3_k127_84324_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 327.0
HFD3_k127_84324_1 Alpha beta hydrolase - GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 318.0
HFD3_k127_84324_2 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000000005037 212.0
HFD3_k127_84324_3 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000002147 199.0
HFD3_k127_84324_4 Acyl-transferase K00655,K01897 - 2.3.1.51,6.2.1.3 0.000000000000000000000000000000000000003602 156.0
HFD3_k127_849323_0 Sulfate ABC transporter periplasmic sulfate-binding protein K02048 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 419.0
HFD3_k127_849323_1 TIGRFAM sulfate ABC transporter K02046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000106 283.0
HFD3_k127_849323_2 TIGRFAM sulfate ABC transporter K02047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003313 274.0
HFD3_k127_849323_3 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000008817 191.0
HFD3_k127_849323_4 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000005453 173.0
HFD3_k127_849323_5 ADP-ribosylglycohydrolase - - - 0.000000000000000000000000000000000000000007688 156.0
HFD3_k127_851228_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000003238 226.0
HFD3_k127_851228_1 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000119 193.0
HFD3_k127_858167_0 PFAM CobN Magnesium Chelatase K02230,K03403 - 6.6.1.1,6.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004994 545.0
HFD3_k127_858167_1 Response regulator containing a CheY-like receiver domain and a GGDEF domain K02488 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 0.00000000000148 73.0
HFD3_k127_858167_2 rRNA binding K02968 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0001086 45.0
HFD3_k127_859628_0 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006651 315.0
HFD3_k127_859628_1 WD-40 repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 324.0
HFD3_k127_867112_0 Dehydrogenase K02030,K17760,K19713 - 1.1.9.1,1.8.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 451.0
HFD3_k127_86716_0 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 406.0
HFD3_k127_86716_1 Domain of unknown function (DUF4287) - - - 0.000000000000000000000000000000000000000000000000000000000000000001228 233.0
HFD3_k127_86716_2 Zn peptidase K21686 - - 0.0000000000000000000000007364 112.0
HFD3_k127_86716_3 Rad52 22 double-strand break repair protein - - - 0.0000000004582 71.0
HFD3_k127_86716_4 sequence-specific DNA binding - - - 0.000000001545 65.0
HFD3_k127_869926_0 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005818 382.0
HFD3_k127_869926_1 6-phosphogluconolactonase activity - - - 0.000000000000002549 90.0
HFD3_k127_869926_2 pfam yhs - - - 0.00000000003266 66.0
HFD3_k127_870630_0 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004135 317.0
HFD3_k127_87735_0 SPTR Beta-galactosidase I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007503 416.0
HFD3_k127_87735_1 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000565 205.0
HFD3_k127_87735_2 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.000000000000000000000000000000000000000000000000005699 182.0
HFD3_k127_87735_3 PDZ DHR GLGF domain protein - - - 0.000000000000000000000000000000000000001703 162.0
HFD3_k127_87735_4 Protein of unknown function (DUF1203) - - - 0.000000000000000000000003377 110.0
HFD3_k127_87735_5 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000003871 108.0
HFD3_k127_87735_6 PFAM SpoVT AbrB - - - 0.00000000000004433 77.0
HFD3_k127_87735_7 - - - - 0.0000000000005012 75.0
HFD3_k127_882826_0 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007503 256.0
HFD3_k127_882826_1 Participates in the control of copper homeostasis K06201 GO:0006873,GO:0006875,GO:0006878,GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0019725,GO:0030003,GO:0042221,GO:0042592,GO:0046688,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055070,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0098771 - 0.000000000000000000000000000000000000000000462 166.0
HFD3_k127_883599_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 8.21e-247 774.0
HFD3_k127_883599_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.000000000000000000000000006666 112.0
HFD3_k127_883599_3 TPR repeat - - - 0.000000003071 65.0
HFD3_k127_887522_0 Domain of unknown function (DUF4070) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 528.0
HFD3_k127_887522_1 CarD-like/TRCF domain K07736 - - 0.00001082 53.0
HFD3_k127_889828_0 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 396.0
HFD3_k127_889828_1 PFAM Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000001446 183.0
HFD3_k127_889828_2 Chain length determinant protein - - - 0.000000000000000000000001871 114.0
HFD3_k127_889828_3 Polysaccharide deacetylase - - - 0.000000000000000000000331 108.0
HFD3_k127_889828_4 export protein K01991 - - 0.0000000000000000000434 99.0
HFD3_k127_889828_5 Chain length determinant protein - - - 0.00001497 57.0
HFD3_k127_891052_0 DNA-templated transcription, initiation K02405 - - 0.0000000000000000000000000000000000000000000000000000000002599 210.0
HFD3_k127_891052_1 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000343 205.0
HFD3_k127_891052_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000003922 183.0
HFD3_k127_891052_3 Belongs to the 'phage' integrase family K03733,K04763 - - 0.0003834 46.0
HFD3_k127_892015_0 Protein of unknown function (DUF1553) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005591 561.0
HFD3_k127_900698_0 Lysin motif K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003244 271.0
HFD3_k127_90805_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005429 290.0
HFD3_k127_90805_1 transcriptional regulator (RpiR family) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002881 250.0
HFD3_k127_909306_0 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005519 537.0
HFD3_k127_909306_1 12 heme-binding sites - - - 0.00000000001218 75.0
HFD3_k127_909306_2 PFAM Class III cytochrome C family - - - 0.00008123 52.0
HFD3_k127_909306_3 heat shock protein binding - - - 0.000417 49.0
HFD3_k127_925720_0 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000000000007347 95.0
HFD3_k127_927455_0 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 324.0
HFD3_k127_927455_1 TIGRFAM polysaccharide deactylase family protein, PEP-CTERM locus subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 303.0
HFD3_k127_927455_2 methyltransferase - - - 0.00000000000000000000000004546 117.0
HFD3_k127_927455_3 PFAM asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000149 110.0
HFD3_k127_927455_4 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00066 - 1.1.1.132 0.0000000000000000000000509 100.0
HFD3_k127_935277_0 Protein of unknown function (DUF1553) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 566.0
HFD3_k127_935277_1 NADPH-dependent FMN reductase - - - 0.000000000004115 67.0
HFD3_k127_937682_0 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001667 292.0
HFD3_k127_937682_1 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000002476 239.0
HFD3_k127_937682_2 peptide deformylase activity K01462 - 3.5.1.88 0.00000000000000000000000000000000000001931 145.0
HFD3_k127_938250_0 TrkA-C domain K03499 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000001169 180.0
HFD3_k127_938250_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000004156 158.0
HFD3_k127_938250_2 Putative NAD(P)-binding K03499 - - 0.0000000000000000000001397 111.0
HFD3_k127_938250_3 TPR repeat - - - 0.0000000000000000001643 97.0
HFD3_k127_938250_4 Tetratricopeptide repeat - - - 0.00000000000004212 76.0
HFD3_k127_946911_0 Domain of unknown function (DUF4388) - - - 0.000000000000002705 89.0
HFD3_k127_946911_1 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.0000000002066 69.0
HFD3_k127_946911_2 molecular chaperone K03686 - - 0.0000004718 63.0
HFD3_k127_947950_0 Hep Hag repeat protein - - - 0.0000000000000000000000000001882 128.0
HFD3_k127_947950_1 Hep Hag repeat protein - - - 0.000000009845 66.0
HFD3_k127_948989_0 COG1136 ABC-type antimicrobial peptide transport system ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 298.0
HFD3_k127_948989_1 ABC transporter permease K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002221 263.0
HFD3_k127_951863_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 497.0
HFD3_k127_951863_1 alpha,alpha-trehalase activity K01194,K03931 GO:0003674,GO:0003824,GO:0004553,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015926,GO:0016787,GO:0016798,GO:0033554,GO:0050896,GO:0051716 3.2.1.28 0.000000000000000000000000000000000000000001567 174.0
HFD3_k127_951863_2 Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system - - - 0.00000000000000000000000000000003041 136.0
HFD3_k127_951863_3 CAAX protease self-immunity - - - 0.000000000000000000000000003951 120.0
HFD3_k127_951863_4 Regulates arginine biosynthesis genes K03402 - - 0.000000000000000000003302 98.0
HFD3_k127_952492_0 TonB dependent receptor K16090 - - 1.017e-224 720.0
HFD3_k127_952492_1 ABC1 family K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006889 611.0
HFD3_k127_952492_2 Asparaginyl-tRNA synthetase K01893 GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 443.0
HFD3_k127_952492_3 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 398.0
HFD3_k127_952492_4 protein-disulfide reductase activity K01999,K08309 - - 0.00000000000000000000005155 106.0
HFD3_k127_956524_0 Transcriptional regulator K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 332.0
HFD3_k127_956524_1 Protein of unknown function (DUF418) K07148 - - 0.00000000000000000000000000000000000000000000000000000000000000009556 232.0
HFD3_k127_956524_2 Transcriptional regulator K03641 - - 0.000000000001688 70.0
HFD3_k127_956791_0 - K07018 - - 0.0000000000000000000000000000000000000000000000000001241 194.0
HFD3_k127_956791_1 Phosphodiester glycosidase - - - 0.0000000000000000000000000000000000003158 154.0
HFD3_k127_964896_0 TIGRFAM rhamnulose-1-phosphate aldolase alcohol dehydrogenase - - - 1.314e-317 986.0
HFD3_k127_964896_1 alpha/beta hydrolase fold K07214 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 376.0
HFD3_k127_964896_2 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004346 255.0
HFD3_k127_964896_3 Bacterial alpha-L-rhamnosidase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001722 247.0
HFD3_k127_964896_4 alpha/beta hydrolase fold - - - 0.0000000000000000000000000004236 114.0
HFD3_k127_968074_0 Predicted membrane protein (DUF2339) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001054 295.0
HFD3_k127_968074_1 PFAM Glycoside hydrolase, family 3, N-terminal K05349 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000001218 266.0
HFD3_k127_968074_2 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.00000000000000000000000000000000000000000000000008942 181.0
HFD3_k127_968074_3 NUDIX domain K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000002002 168.0
HFD3_k127_968074_4 Belongs to the ompA family - - - 0.00000000000000000000000000000009318 134.0
HFD3_k127_973685_0 phosphatidate phosphatase activity K09474,K19302 - 3.1.3.2,3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 400.0
HFD3_k127_973685_1 Ornithine decarboxylase inhibitor-putative sigma54 transciptional regulator K02584 - - 0.00000000000000000000000000000002376 140.0
HFD3_k127_973685_2 Transcriptional regulatory protein, C terminal - - - 0.0000000001164 64.0
HFD3_k127_974440_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 424.0
HFD3_k127_974704_0 methyltransferase activity K00574,K12240,K18534,K19620,K20444 - 2.1.1.295,2.1.1.79 0.000000000000000000000000000000000322 134.0
HFD3_k127_974704_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000004388 125.0
HFD3_k127_976348_0 DinB family - - - 0.0000000000000000000000000000006636 127.0
HFD3_k127_976348_1 Protein of unknown function (DUF1326) - - - 0.0000000000000000000000000000009532 131.0
HFD3_k127_976348_3 - - - - 0.000000002416 65.0
HFD3_k127_980725_0 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000003681 220.0
HFD3_k127_980725_1 Protein of unknown function (DUF3108) - - - 0.00000000000000000218 95.0
HFD3_k127_983365_0 Hep Hag repeat protein - - - 0.00000000000000002556 93.0
HFD3_k127_983365_1 Hep Hag repeat protein - - - 0.0000000000003468 83.0
HFD3_k127_987470_0 Glycosyl transferases group 1 K00754 - - 0.00000000000000000000000000000000000000000000000005375 188.0
HFD3_k127_987470_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000398 49.0
HFD3_k127_987530_0 FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.00000000000000000000000000000000000000004416 156.0
HFD3_k127_987530_1 von Willebrand factor, type A - - - 0.00000000000000000000000000000000002337 148.0
HFD3_k127_987530_2 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.000000000000000000001884 98.0
HFD3_k127_992936_0 AcrB/AcrD/AcrF family - - - 2.021e-241 759.0
HFD3_k127_992936_1 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000009893 159.0
HFD3_k127_998734_0 Penicillinase repressor - - - 0.0000000000000002993 83.0
HFD3_k127_998734_1 BlaR1 peptidase M56 - - - 0.0000000000003407 79.0
HFD3_k127_998734_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000001965 68.0
HFD3_k127_998771_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 337.0
HFD3_k127_998771_1 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.0000000000000000000000000000000000000000000000000000000000000000003182 246.0