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Overview

ID MAG01685
Name HFD3_bin.26
Sample SMP0045
Taxonomy
Kingdom Bacteria
Phylum Myxococcota
Class Myxococcia
Order Myxococcales
Family Anaeromyxobacteraceae
Genus DASTPH01
Species
Assembly information
Completeness (%) 87.88
Contamination (%) 2.23
GC content (%) 75.0
N50 (bp) 7,168
Genome size (bp) 4,193,269

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3785

Gene name Description KEGG GOs EC E-value Score Sequence
HFD3_k127_1011308_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000004105 243.0
HFD3_k127_1011308_1 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.000000000000000000000000000000000000000001735 168.0
HFD3_k127_1019274_0 4Fe-4S dicluster domain - - - 1.966e-261 844.0
HFD3_k127_1019274_1 PFAM Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004993 492.0
HFD3_k127_1019274_2 PFAM Nitrate reductase gamma subunit K00374 - 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 387.0
HFD3_k127_1019274_3 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 306.0
HFD3_k127_1019274_4 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000003627 240.0
HFD3_k127_1019274_5 Sirohaem biosynthesis protein central K02304 - 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000005248 153.0
HFD3_k127_1019274_6 sulfur relay protein, TusE DsrC DsvC family K11179 - - 0.00000000000000000000000000000000000266 154.0
HFD3_k127_1019274_7 - - - - 0.0000000000000000000000000000002982 128.0
HFD3_k127_1019274_8 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.000000000000000000000000002103 121.0
HFD3_k127_1019274_9 Sulfotransferase domain - - - 0.0000007486 61.0
HFD3_k127_1022414_0 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 402.0
HFD3_k127_1022414_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 370.0
HFD3_k127_1022414_2 Pkd domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006821 325.0
HFD3_k127_1022414_3 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000004529 262.0
HFD3_k127_1022414_4 chaperone-mediated protein folding - - - 0.0000000000000000000000000001883 133.0
HFD3_k127_1022414_5 Stigma-specific protein, Stig1 - - - 0.000000000000000000002962 108.0
HFD3_k127_1022414_6 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.000000000000000000007423 96.0
HFD3_k127_1022414_8 ABC transporter K01990,K09695 - - 0.000000000003484 67.0
HFD3_k127_1022414_9 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000003977 57.0
HFD3_k127_1023685_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008312 584.0
HFD3_k127_1023685_1 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007375 465.0
HFD3_k127_1023685_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000002272 272.0
HFD3_k127_1023685_3 Rhomboid family K07059 - - 0.0000000000000000000000000000000000000000000000000000000000000000003967 252.0
HFD3_k127_1023685_4 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000000000000000000000000000000002797 217.0
HFD3_k127_1023685_5 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000002823 213.0
HFD3_k127_1023685_6 Acetyl-CoA hydrolase/transferase N-terminal domain - - - 0.00000000000000000000000000009666 115.0
HFD3_k127_1023685_7 - - - - 0.00000000000000000000005829 113.0
HFD3_k127_1035893_0 Large family of predicted nucleotide-binding domains K07175 - - 3.69e-243 756.0
HFD3_k127_1035893_1 diguanylate cyclase - - - 1.388e-238 764.0
HFD3_k127_1035893_2 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 466.0
HFD3_k127_1035893_3 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 445.0
HFD3_k127_1035893_4 Belongs to the UPF0250 family K09158 - - 0.0000000000000000000000000000003826 124.0
HFD3_k127_1035893_5 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589,K13052 - - 0.00000000491 64.0
HFD3_k127_1045556_0 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 441.0
HFD3_k127_1045556_2 tRNA methyltransferase complex GCD14 subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001486 270.0
HFD3_k127_1045556_3 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000002127 220.0
HFD3_k127_1045556_4 Crp-like helix-turn-helix domain K10914 - - 0.000000000000000000000000000000000000000000000000001631 203.0
HFD3_k127_1045556_5 thiamine biosynthesis protein ThiS K03154 - - 0.0000000000000000000002129 113.0
HFD3_k127_1045556_6 Domain of unknown function (DUF4350) - - - 0.00000000000000000005051 106.0
HFD3_k127_1045556_8 - - - - 0.000006866 58.0
HFD3_k127_1058047_0 Glycosyl transferase family 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 521.0
HFD3_k127_1058047_1 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 509.0
HFD3_k127_1058047_2 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000000000005762 200.0
HFD3_k127_1061709_0 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003374 380.0
HFD3_k127_1067021_0 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 411.0
HFD3_k127_1067021_1 ATPase involved in DNA repair K03546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004905 265.0
HFD3_k127_1067021_2 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000002065 201.0
HFD3_k127_1067021_3 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000000000000000000000005289 203.0
HFD3_k127_1067021_4 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000001945 159.0
HFD3_k127_1067021_5 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000204 137.0
HFD3_k127_1067021_6 Belongs to the UPF0109 family K06960 - - 0.000000000000000000000000000324 122.0
HFD3_k127_1067021_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000001395 109.0
HFD3_k127_1069883_0 regulation of single-species biofilm formation K13572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 365.0
HFD3_k127_1069883_1 regulation of single-species biofilm formation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 313.0
HFD3_k127_1069883_2 endonuclease activity K07451 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004823 289.0
HFD3_k127_1069883_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005988 243.0
HFD3_k127_1069883_4 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000000000000000000000000000005238 224.0
HFD3_k127_1069883_5 COGs COG2148 Sugar transferase involved in lipopolysaccharide synthesis - - - 0.000000000000007087 88.0
HFD3_k127_1069883_6 Putative zinc-finger - - - 0.00000005973 63.0
HFD3_k127_107227_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 429.0
HFD3_k127_107227_1 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 377.0
HFD3_k127_107227_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000075 281.0
HFD3_k127_1077567_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 2.702e-224 702.0
HFD3_k127_1077567_1 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 485.0
HFD3_k127_1077567_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 396.0
HFD3_k127_1077567_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000002287 148.0
HFD3_k127_1077567_4 PFAM Amino acid-binding ACT - - - 0.000000000000000000000000000000000001525 158.0
HFD3_k127_1088053_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 3.803e-199 701.0
HFD3_k127_1088053_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008352 458.0
HFD3_k127_1088053_10 PGAP1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005291 293.0
HFD3_k127_1088053_11 PFAM amino acid-binding ACT domain protein - - - 0.000000000000000000000000000000000000000000000000000001722 195.0
HFD3_k127_1088053_12 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.000000000000000000000000000000001617 152.0
HFD3_k127_1088053_13 TrkA-C domain K03455 - - 0.0000000000000000000000000001668 119.0
HFD3_k127_1088053_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 462.0
HFD3_k127_1088053_3 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006025 448.0
HFD3_k127_1088053_4 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005971 417.0
HFD3_k127_1088053_5 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate K00019 - 1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 367.0
HFD3_k127_1088053_6 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 359.0
HFD3_k127_1088053_7 Double sensory domain of two-component sensor kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 363.0
HFD3_k127_1088053_8 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008817 365.0
HFD3_k127_1088053_9 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 310.0
HFD3_k127_110036_0 Belongs to the SAICAR synthetase family K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007461 573.0
HFD3_k127_110036_1 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002318 239.0
HFD3_k127_1105737_0 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 394.0
HFD3_k127_1105737_1 Glyoxalase-like domain K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000008242 186.0
HFD3_k127_1105737_2 4Fe-4S dicluster domain K00125,K03646 - 1.17.1.9 0.000000000000000000000000000000000000000000002144 172.0
HFD3_k127_1105737_4 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00112 - 1.1.5.3 0.00000000000000000006856 91.0
HFD3_k127_1106978_0 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006171 513.0
HFD3_k127_1106978_1 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 423.0
HFD3_k127_1106978_2 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000606 160.0
HFD3_k127_1106978_3 Protein of unknown function (DUF3106) - - - 0.000000000002064 78.0
HFD3_k127_1106978_4 Putative zinc-finger - - - 0.00000427 60.0
HFD3_k127_1115333_0 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 436.0
HFD3_k127_1115333_1 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 401.0
HFD3_k127_1115333_2 Phosphomethylpyrimidine kinase K00941,K14153,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004763 374.0
HFD3_k127_1115333_3 PFAM Alpha beta hydrolase K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008038 361.0
HFD3_k127_1115333_4 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004708 293.0
HFD3_k127_1115333_5 PFAM Acyl-ACP thioesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000001794 254.0
HFD3_k127_1115333_6 FR47-like protein - - - 0.00000000000000000000000000000000000000000000001935 177.0
HFD3_k127_1115333_7 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.00000000000000000000000000000000000266 154.0
HFD3_k127_1115333_8 Histidine kinase - - - 0.00000000000000002221 96.0
HFD3_k127_1115333_9 Domain of unknown function (DUF3943) - - - 0.000001613 61.0
HFD3_k127_1119590_0 PFAM MMPL family K07003 - - 3.836e-318 990.0
HFD3_k127_1119590_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 607.0
HFD3_k127_1119590_10 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000000000000004887 113.0
HFD3_k127_1119590_11 - - - - 0.000000000000000000000004107 104.0
HFD3_k127_1119590_12 - - - - 0.0000000000000000000605 94.0
HFD3_k127_1119590_13 peptidyl-tyrosine sulfation - - - 0.0000000000000000621 93.0
HFD3_k127_1119590_14 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000001863 85.0
HFD3_k127_1119590_15 - - - - 0.000000000001224 68.0
HFD3_k127_1119590_16 Kelch motif - - - 0.00000000001095 78.0
HFD3_k127_1119590_17 - - - - 0.0000000006732 61.0
HFD3_k127_1119590_18 - - - - 0.000000007668 58.0
HFD3_k127_1119590_2 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007363 488.0
HFD3_k127_1119590_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 432.0
HFD3_k127_1119590_4 response to heat K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 399.0
HFD3_k127_1119590_6 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009038 337.0
HFD3_k127_1119590_7 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003486 311.0
HFD3_k127_1119590_8 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005267 270.0
HFD3_k127_1119590_9 - - - - 0.00000000000000000000000000000000000000001576 159.0
HFD3_k127_1125241_0 DNA polymerase K02337,K14162 - 2.7.7.7 0.0 1901.0
HFD3_k127_1125241_1 cellulose binding - - - 8.249e-247 790.0
HFD3_k127_1125241_2 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012,K16180 - 2.8.1.6,5.4.99.58 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 555.0
HFD3_k127_1125241_3 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 379.0
HFD3_k127_1125241_4 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000003788 239.0
HFD3_k127_1125241_5 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000001608 181.0
HFD3_k127_1125241_6 Dodecin K09165 - - 0.00000000000000000000003315 117.0
HFD3_k127_1125241_7 - - - - 0.0000000000000000000005859 103.0
HFD3_k127_1125241_8 4Fe-4S single cluster domain - - - 0.0000002927 57.0
HFD3_k127_1135082_0 benzoyl-CoA reductase K04113 - 1.3.7.8 7.667e-224 730.0
HFD3_k127_1135082_1 Acyl-CoA dehydrogenase, middle domain K00252 - 1.3.8.6 6.859e-203 637.0
HFD3_k127_1135082_2 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 639.0
HFD3_k127_1135082_3 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 608.0
HFD3_k127_1135082_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07538 - 1.1.1.368 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 531.0
HFD3_k127_1135082_5 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005509 332.0
HFD3_k127_1135082_6 Benzoyl-CoA reductase subunit K04114 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000003874 250.0
HFD3_k127_1135082_7 transcriptional regulator - - - 0.000000000000007679 76.0
HFD3_k127_113643_0 Histidine kinase K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 608.0
HFD3_k127_113643_1 dipeptide transport K02035 - - 0.00000000000000000000000000000000000000000000001487 183.0
HFD3_k127_113643_2 domain, Protein - - - 0.00000000002955 71.0
HFD3_k127_1138022_0 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 1.374e-211 661.0
HFD3_k127_1138022_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 507.0
HFD3_k127_1138022_2 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 334.0
HFD3_k127_1138022_3 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 303.0
HFD3_k127_1138022_4 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000003507 211.0
HFD3_k127_1138022_5 MerR, DNA binding K19591 - - 0.0000000000000000000000000000000000000000000000000000002661 199.0
HFD3_k127_1144405_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008385 340.0
HFD3_k127_1144405_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00615,K00616,K13810 - 2.2.1.1,2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000008094 266.0
HFD3_k127_1144405_2 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000001049 224.0
HFD3_k127_1144405_3 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.000000000000000000000000001837 118.0
HFD3_k127_1147051_0 cytochrome c - GO:0005575,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017004,GO:0022607,GO:0031224,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0065003,GO:0071840 - 4.095e-269 859.0
HFD3_k127_1147051_1 cytochrome c biogenesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 550.0
HFD3_k127_1147051_2 NAD(P)H quinone oxidoreductase, PIG3 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 535.0
HFD3_k127_1147051_4 - - - - 0.000000000000000000000000000000000000000000000000000001629 194.0
HFD3_k127_1148734_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 5.052e-268 834.0
HFD3_k127_1148734_1 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 396.0
HFD3_k127_1148734_2 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 391.0
HFD3_k127_1148734_3 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007663 312.0
HFD3_k127_1148734_4 SurA N-terminal domain K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008882 306.0
HFD3_k127_1156929_0 Belongs to the glycosyl hydrolase 57 family - - - 1.292e-299 933.0
HFD3_k127_1156929_1 of the major facilitator superfamily K08151 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 374.0
HFD3_k127_1176387_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1292.0
HFD3_k127_1176387_1 twitching motility protein K02669 - - 2.913e-216 674.0
HFD3_k127_1176387_10 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000000000000000000000000007131 175.0
HFD3_k127_1176387_11 protein trimerization - - - 0.00000000000000000000000000000000000000007021 174.0
HFD3_k127_1176387_12 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000000000000013 149.0
HFD3_k127_1176387_13 alkyl hydroperoxide reductase activity - - - 0.0000000000000000000001826 98.0
HFD3_k127_1176387_2 nuclear chromosome segregation K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 492.0
HFD3_k127_1176387_3 AAA domain (Cdc48 subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 450.0
HFD3_k127_1176387_4 PilZ domain K02676 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 404.0
HFD3_k127_1176387_5 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 407.0
HFD3_k127_1176387_6 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 301.0
HFD3_k127_1176387_7 DNA recombination-mediator protein A K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000846 301.0
HFD3_k127_1176387_8 MotA/TolQ/ExbB proton channel family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003171 256.0
HFD3_k127_1176387_9 alkyl hydroperoxide reductase activity - - - 0.0000000000000000000000000000000000000000000000000002422 196.0
HFD3_k127_1179103_0 Transcriptional regulator - - - 2.389e-271 867.0
HFD3_k127_1179103_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006079 363.0
HFD3_k127_1179103_2 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000003914 158.0
HFD3_k127_121570_0 Signal transduction histidine kinase K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 482.0
HFD3_k127_121570_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000002583 229.0
HFD3_k127_1256037_0 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008341 438.0
HFD3_k127_1256037_1 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000001165 235.0
HFD3_k127_1256037_2 Membrane K08988 - - 0.00000000000000000000000000000000000000000000000000000000000000004272 228.0
HFD3_k127_1260897_0 protein kinase activity - - - 1.213e-239 752.0
HFD3_k127_1260897_1 histone H2A K63-linked ubiquitination - - - 0.00000000000000000000000000000002128 135.0
HFD3_k127_1269201_0 regulation of microtubule-based process K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004172 456.0
HFD3_k127_1269201_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 375.0
HFD3_k127_1269201_2 - - - - 0.00000000000000000000000000000000000001542 153.0
HFD3_k127_1273956_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 523.0
HFD3_k127_1273956_1 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005127 413.0
HFD3_k127_1273956_2 ATP synthesis coupled proton transport K02109 - - 0.0000000000000000000000000000000000000000000000000000000005803 211.0
HFD3_k127_1273956_3 ATP hydrolysis coupled proton transport K02110,K02124 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000001322 108.0
HFD3_k127_1273956_6 Aminotransferase K01845 - 5.4.3.8 0.0000001715 53.0
HFD3_k127_1274483_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 1.206e-290 900.0
HFD3_k127_1274483_1 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 302.0
HFD3_k127_1274483_2 6-O-methylguanine DNA methyltransferase, DNA binding domain K07443 - - 0.00000000000000000000000000000000000000000004925 163.0
HFD3_k127_1290433_0 FIST N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 472.0
HFD3_k127_1290433_1 Belongs to the peptidase S26 family - - - 0.0000000000000000000000000000001508 143.0
HFD3_k127_1290433_2 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000008719 109.0
HFD3_k127_1290433_3 PFAM Abortive infection protein K07052 - - 0.0000000000000000000000004525 121.0
HFD3_k127_1298810_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 1.53e-321 1024.0
HFD3_k127_1298810_1 Pfam Transposase IS66 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 474.0
HFD3_k127_1298810_2 PFAM iron dependent repressor K03709 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 340.0
HFD3_k127_1298810_3 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000000000003373 224.0
HFD3_k127_1298810_4 FMN_bind - - - 0.000000000000000000000000000000000000000000000000000149 207.0
HFD3_k127_1298810_6 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000005887 160.0
HFD3_k127_1298810_7 - - - - 0.0000000000000000000000000000000000000005105 162.0
HFD3_k127_1298810_9 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC K06148,K16012 - - 0.000000000000000000000000005975 117.0
HFD3_k127_130214_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 3.25e-200 629.0
HFD3_k127_130214_1 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 561.0
HFD3_k127_130214_2 PFAM permease YjgP YjgQ family protein K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001207 282.0
HFD3_k127_130214_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000002306 225.0
HFD3_k127_130214_4 peptidyl-tyrosine sulfation - - - 0.000000000000000009286 98.0
HFD3_k127_1302642_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 4.925e-211 661.0
HFD3_k127_1302642_1 Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 606.0
HFD3_k127_1302642_2 Serine Threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 329.0
HFD3_k127_1302642_3 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002456 269.0
HFD3_k127_1302642_4 Is able to transfer iron-sulfur clusters to apo- ferredoxin. Multiple cycles of 2Fe2S cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system K13628 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009058,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0016530,GO:0018130,GO:0019438,GO:0019538,GO:0022607,GO:0031163,GO:0031974,GO:0033013,GO:0033014,GO:0034641,GO:0034986,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0051604,GO:0070013,GO:0071704,GO:0071840,GO:0097428,GO:0140104,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000004156 196.0
HFD3_k127_1302642_6 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.00000001262 56.0
HFD3_k127_1308892_0 phospho-2-dehydro-3-deoxyheptonate aldolase K03856,K04516 - 2.5.1.54,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007444 559.0
HFD3_k127_1308892_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 411.0
HFD3_k127_1308892_2 phospho-2-dehydro-3-deoxyheptonate aldolase K03856,K04516 - 2.5.1.54,5.4.99.5 0.0000000000000000000000000000000000000000000008118 168.0
HFD3_k127_1317142_0 oligopeptide transporter, OPT family - - - 0.0 1069.0
HFD3_k127_1317142_1 Responsible for synthesis of pseudouridine from uracil K06179,K06180 - 5.4.99.23,5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 419.0
HFD3_k127_1317142_2 metalloendopeptidase activity K08602 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 419.0
HFD3_k127_1317142_4 CoA binding domain K06929 - - 0.000000000000000000000000000000000000000000000000000000000000001029 221.0
HFD3_k127_1317142_5 PFAM Rhomboid family protein K19225 - 3.4.21.105 0.000000000000000000000000000007363 128.0
HFD3_k127_1317142_7 Regulatory protein, FmdB family - - - 0.0000000000000000000001398 100.0
HFD3_k127_1317142_8 Metallo-beta-lactamase superfamily - - - 0.0000006957 60.0
HFD3_k127_131883_0 Type III secretion protein K03230 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009059 505.0
HFD3_k127_131883_1 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401,K03229 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 302.0
HFD3_k127_131883_2 type iii secretion K03226 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004778 260.0
HFD3_k127_131883_3 bacterial-type flagellum assembly K02421,K03228,K13820 - - 0.0000000000000000000000000000000000000000000000000000000002905 226.0
HFD3_k127_131883_4 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02416,K02417,K03225 GO:0005575,GO:0005623,GO:0005886,GO:0006935,GO:0008150,GO:0009288,GO:0009425,GO:0009605,GO:0016020,GO:0040011,GO:0042221,GO:0042330,GO:0042995,GO:0043226,GO:0043228,GO:0044403,GO:0044419,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0052116,GO:0052126,GO:0052127,GO:0052143,GO:0052192,GO:0052195,GO:0052216,GO:0052243,GO:0071944 - 0.000000000000000000000000000000000000000000000000005852 186.0
HFD3_k127_131883_5 Flagellar biosynthetic protein FliQ K02420,K03227 - - 0.00000000000000000000000003064 109.0
HFD3_k127_132481_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 568.0
HFD3_k127_132481_1 Belongs to the SEDS family K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009774 522.0
HFD3_k127_132481_2 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 381.0
HFD3_k127_132481_3 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000002208 261.0
HFD3_k127_132481_4 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000000000000002121 189.0
HFD3_k127_132481_5 - - - - 0.0000000000000000000000000000000000000000000005092 189.0
HFD3_k127_132481_6 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.000000000004646 68.0
HFD3_k127_1325127_0 Arginosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004146 569.0
HFD3_k127_1325127_1 Male sterility protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 494.0
HFD3_k127_1325127_2 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000002223 246.0
HFD3_k127_1325127_3 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000005171 209.0
HFD3_k127_1325127_4 - - - - 0.000000000000000000000000000000000000000000000000000000001061 202.0
HFD3_k127_1325127_5 MaoC like domain - - - 0.00000000000000000000000000000000000000000000004797 188.0
HFD3_k127_133174_0 Acetamidase/Formamidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 435.0
HFD3_k127_133174_1 Putative neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 359.0
HFD3_k127_133174_2 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000000003338 185.0
HFD3_k127_133174_3 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000204 133.0
HFD3_k127_133174_4 - - - - 0.000000000000000000000000000000007588 131.0
HFD3_k127_133434_0 Aldehyde dehydrogenase family K00129 - 1.2.1.5 2.229e-227 717.0
HFD3_k127_133434_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 502.0
HFD3_k127_133434_10 PFAM helix-turn-helix domain protein - - - 0.0000000000000000000000000001307 115.0
HFD3_k127_133434_2 DNA-binding transcription factor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 481.0
HFD3_k127_133434_3 protein conserved in bacteria K09927 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 458.0
HFD3_k127_133434_4 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006355 412.0
HFD3_k127_133434_5 Alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000008828 231.0
HFD3_k127_133434_6 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000002576 194.0
HFD3_k127_133434_7 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000000006956 170.0
HFD3_k127_133434_8 Belongs to the Dps family K04047 - - 0.00000000000000000000000000000000000006962 154.0
HFD3_k127_133434_9 - - - - 0.000000000000000000000000000000007458 139.0
HFD3_k127_1359093_0 Enoyl-CoA hydratase/isomerase K11264 - 4.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006445 345.0
HFD3_k127_1359093_1 Response regulator, receiver K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001641 271.0
HFD3_k127_1359093_3 Acetyl propionyl-CoA carboxylase alpha subunit K02160 - - 0.000000000000000000000001383 113.0
HFD3_k127_1359093_4 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000002009 81.0
HFD3_k127_1360931_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003331 601.0
HFD3_k127_1366382_0 ATP-grasp - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009395 342.0
HFD3_k127_1366382_1 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008477 256.0
HFD3_k127_1366382_2 Protein involved in cellulose biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001627 265.0
HFD3_k127_1366382_3 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000003598 244.0
HFD3_k127_1368940_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001765 254.0
HFD3_k127_1368940_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000001029 190.0
HFD3_k127_1368940_2 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000006658 85.0
HFD3_k127_1376382_0 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 485.0
HFD3_k127_1376382_1 PFAM Silent information regulator protein Sir2 K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 402.0
HFD3_k127_1376382_2 ApaG domain K06195 - - 0.00000000000000000000000000000000000000000000002872 174.0
HFD3_k127_1376382_3 Glucose Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000001389 166.0
HFD3_k127_137668_0 SMART helicase c2 K03722 - 3.6.4.12 1.321e-291 907.0
HFD3_k127_1400411_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.29e-213 671.0
HFD3_k127_1400411_1 PFAM Aminotransferase class I and II K10206,K14261 - 2.6.1.83 2.907e-209 665.0
HFD3_k127_1400411_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 525.0
HFD3_k127_1400411_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000005057 257.0
HFD3_k127_1422081_0 RNA polymerase recycling family C-terminal K03580 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 588.0
HFD3_k127_1422081_1 Amidohydrolase family K05603 - 3.5.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 527.0
HFD3_k127_1422081_2 PFAM peptidase M20 K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 556.0
HFD3_k127_1422081_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007662 322.0
HFD3_k127_1423645_0 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006219 392.0
HFD3_k127_1423645_1 Transcriptional regulatory protein, C terminal K07658 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009385 323.0
HFD3_k127_1423645_2 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.0000000000000000000000000000000000000000000000000000001972 197.0
HFD3_k127_143065_0 Carboxyl transferase domain - - - 0.0 1052.0
HFD3_k127_143065_1 PFAM biotin lipoyl attachment domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008193 400.0
HFD3_k127_143065_2 Acyl CoA binding protein K08762 GO:0000038,GO:0000062,GO:0000166,GO:0001300,GO:0003674,GO:0005215,GO:0005319,GO:0005324,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006810,GO:0006811,GO:0006820,GO:0006869,GO:0007568,GO:0007569,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0010876,GO:0015711,GO:0015718,GO:0015849,GO:0015908,GO:0015909,GO:0016053,GO:0017076,GO:0019752,GO:0030554,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033036,GO:0033218,GO:0036042,GO:0036094,GO:0042761,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046942,GO:0048037,GO:0048869,GO:0050662,GO:0051179,GO:0051234,GO:0071702,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901576,GO:1901681 - 0.000000000000000000000406 99.0
HFD3_k127_1434549_0 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 1.42e-289 911.0
HFD3_k127_1434549_1 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 422.0
HFD3_k127_1434549_2 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 345.0
HFD3_k127_1434549_4 diguanylate cyclase - - - 0.00000000001826 65.0
HFD3_k127_143636_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1227.0
HFD3_k127_143636_1 histone H2A-K13 ubiquitination K01338,K07157 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000007911 232.0
HFD3_k127_143636_2 UDP binding domain K00012 - 1.1.1.22 0.000000000000000000000000000004551 120.0
HFD3_k127_1436554_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.218e-249 782.0
HFD3_k127_1436554_1 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 346.0
HFD3_k127_1436554_2 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 312.0
HFD3_k127_1436554_3 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 295.0
HFD3_k127_1436554_4 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000009745 233.0
HFD3_k127_1436554_5 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000004562 198.0
HFD3_k127_1442999_0 PFAM ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 616.0
HFD3_k127_1442999_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000003243 235.0
HFD3_k127_1443798_0 chaperone-mediated protein folding K21007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 502.0
HFD3_k127_1465007_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 2.556e-286 889.0
HFD3_k127_1465007_1 Mitochondrial biogenesis AIM24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004632 401.0
HFD3_k127_1465007_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000005018 267.0
HFD3_k127_1465007_3 Transglycosylase K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000159 258.0
HFD3_k127_1465007_4 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000003857 218.0
HFD3_k127_1465007_6 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0000000000000000000000000000006457 123.0
HFD3_k127_1465007_7 - - - - 0.00000000007646 70.0
HFD3_k127_1465007_8 DNA integration - - - 0.000001674 49.0
HFD3_k127_1469323_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 2.149e-219 710.0
HFD3_k127_1469323_1 dioxygenase K00457,K16421 - 1.13.11.27,1.13.11.46 2.339e-204 640.0
HFD3_k127_1469323_10 thiolester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000001192 211.0
HFD3_k127_1469323_11 IMP dehydrogenase activity - - - 0.00000000000000000000000000000003716 143.0
HFD3_k127_1469323_12 - - - - 0.00000000000000000000002754 117.0
HFD3_k127_1469323_2 homogentisate 12-dioxygenase K00451 - 1.13.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 615.0
HFD3_k127_1469323_3 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000597 561.0
HFD3_k127_1469323_4 Fumarylacetoacetate (FAA) hydrolase family K16171 - 3.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005615 489.0
HFD3_k127_1469323_5 Dienelactone hydrolase family K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 320.0
HFD3_k127_1469323_6 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 291.0
HFD3_k127_1469323_7 maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000001389 265.0
HFD3_k127_1469323_8 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000001243 246.0
HFD3_k127_1469323_9 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000001781 229.0
HFD3_k127_1469889_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 356.0
HFD3_k127_1469889_1 - - - - 0.00000000000000000000000000000000000000000000000000000000003021 222.0
HFD3_k127_1469889_2 Membrane protein, TerC - - - 0.0000000000000000000000000000000000000000000000002632 178.0
HFD3_k127_1480817_0 Amino acid permease - - - 8.364e-249 779.0
HFD3_k127_1480817_1 Patatin-like phospholipase - - - 2.314e-204 646.0
HFD3_k127_1480817_2 Amino-transferase class IV K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 489.0
HFD3_k127_1486401_0 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 507.0
HFD3_k127_1486401_1 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 319.0
HFD3_k127_1486401_2 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000009195 111.0
HFD3_k127_1486401_3 Cellulase (glycosyl hydrolase family 5) K01218 - 3.2.1.78 0.0000008686 56.0
HFD3_k127_1491573_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 2.575e-262 813.0
HFD3_k127_1491573_1 penicillin-binding protein K03587 - 3.4.16.4 7.267e-233 742.0
HFD3_k127_1491573_10 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000003106 231.0
HFD3_k127_1491573_12 cell division K03586 GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0019954,GO:0022402,GO:0022414,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0043093,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944 - 0.00000000000008096 84.0
HFD3_k127_1491573_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 611.0
HFD3_k127_1491573_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 596.0
HFD3_k127_1491573_4 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 607.0
HFD3_k127_1491573_5 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 588.0
HFD3_k127_1491573_6 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007074 526.0
HFD3_k127_1491573_7 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 454.0
HFD3_k127_1491573_8 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006833 431.0
HFD3_k127_1491573_9 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 345.0
HFD3_k127_1496108_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 4.067e-278 859.0
HFD3_k127_1496108_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 7.938e-228 719.0
HFD3_k127_1496108_2 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 604.0
HFD3_k127_1496108_3 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 524.0
HFD3_k127_1496108_4 Transcriptional regulator, CarD family K07736 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 311.0
HFD3_k127_1496108_5 Penicillin amidase K01434 - 3.5.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001387 309.0
HFD3_k127_151180_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005414 498.0
HFD3_k127_151180_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000581 376.0
HFD3_k127_151180_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 297.0
HFD3_k127_151180_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006591 291.0
HFD3_k127_151180_4 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000001735 244.0
HFD3_k127_151180_5 Binds together with S18 to 16S ribosomal RNA K01754,K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 4.3.1.19 0.000000000000000000000000000000000000000000000000000001801 195.0
HFD3_k127_151180_7 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000267 148.0
HFD3_k127_151180_8 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000002957 117.0
HFD3_k127_151180_9 Could be involved in septation K06412 GO:0000003,GO:0008150,GO:0019954,GO:0030436,GO:0032502,GO:0043934 - 0.000000000000000006975 87.0
HFD3_k127_1548902_0 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 487.0
HFD3_k127_1548902_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004619 405.0
HFD3_k127_1548902_2 shikimate kinase activity K00891,K13829 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000002486 203.0
HFD3_k127_1548902_3 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000001534 209.0
HFD3_k127_1552207_0 ribonuclease Rne Rng family K08301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 412.0
HFD3_k127_1552207_1 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 345.0
HFD3_k127_1552207_2 Belongs to the bacterial histone-like protein family K05788 - - 0.00000000000000000000000000000000000000000000000000000006024 198.0
HFD3_k127_1552207_3 Type III secretion protein K03230 - - 0.000000000000000000000000000000000000005564 148.0
HFD3_k127_1558683_0 Chalcone and stilbene synthases, C-terminal domain K16167,K19580 - 2.3.1.233 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005718 505.0
HFD3_k127_1558683_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695,K03696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006094 442.0
HFD3_k127_1558683_2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K16168 - - 0.00000000000000000000000000000000000000000000000000157 205.0
HFD3_k127_1558683_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000007686 179.0
HFD3_k127_1558683_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000412 72.0
HFD3_k127_1576652_0 PFAM Prolyl oligopeptidase family - - - 5.683e-240 753.0
HFD3_k127_1576652_1 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 449.0
HFD3_k127_1576652_2 TAP-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 354.0
HFD3_k127_1579746_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 9.104e-299 922.0
HFD3_k127_1579746_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 2.213e-233 777.0
HFD3_k127_1579746_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 342.0
HFD3_k127_1579746_3 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 329.0
HFD3_k127_1579746_4 Protein of unknown function (DUF503) K09764 - - 0.00000000000000000000000000000000000000000000000003777 181.0
HFD3_k127_1579746_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000000000000000001901 178.0
HFD3_k127_1579746_6 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000006647 156.0
HFD3_k127_1580783_0 WD40-like Beta Propeller Repeat - - - 1.123e-298 948.0
HFD3_k127_1580783_1 Aminotransferase K00812 - 2.6.1.1 3.607e-195 617.0
HFD3_k127_1580783_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000002697 228.0
HFD3_k127_1580783_12 Cytochrome c K00413 - - 0.0000000000000000000000000000000000000000000000000000000564 219.0
HFD3_k127_1580783_13 Serine hydrolase K07002 - - 0.000000000000000000000000000000000000000000000000000005006 204.0
HFD3_k127_1580783_2 Cation efflux family K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 389.0
HFD3_k127_1580783_3 PS-10 peptidase S37 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006244 368.0
HFD3_k127_1580783_4 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 340.0
HFD3_k127_1580783_5 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004825 349.0
HFD3_k127_1580783_6 Bacterial transcriptional repressor C-terminal K16137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 292.0
HFD3_k127_1580783_7 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000006418 253.0
HFD3_k127_1580783_8 PFAM Activator of Hsp90 ATPase 1 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005912 250.0
HFD3_k127_1580783_9 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000004512 234.0
HFD3_k127_1582767_0 PFAM glycosyl transferase family 51 K05366 - 2.4.1.129,3.4.16.4 0.0 1220.0
HFD3_k127_1582767_1 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 593.0
HFD3_k127_1582767_2 Mediates influx of magnesium ions K03284,K16074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006324 520.0
HFD3_k127_1582767_3 Exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 494.0
HFD3_k127_1582767_4 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 472.0
HFD3_k127_1582767_5 epoxide hydrolase K01253 - 3.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 405.0
HFD3_k127_1582767_6 Thiol disulfide interchange protein dsbA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 387.0
HFD3_k127_1582767_7 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000003573 237.0
HFD3_k127_1582767_8 Tetratricopeptide repeat - - - 0.000000000000000000000000006628 128.0
HFD3_k127_1582767_9 EamA-like transporter family - - - 0.00000000000000000000002082 100.0
HFD3_k127_158296_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 0.0 2169.0
HFD3_k127_158296_1 Nitrate reductase, beta subunit K00371,K17051 - 1.7.5.1 1.608e-264 820.0
HFD3_k127_158296_2 PFAM major facilitator superfamily MFS_1 K02575 - - 8.812e-213 690.0
HFD3_k127_158296_3 Involved in the tonB-independent uptake of proteins K03641,K10117 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 428.0
HFD3_k127_158296_4 TIGRFAM respiratory nitrate reductase, gamma subunit K00374 - 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001041 294.0
HFD3_k127_158296_5 PFAM regulatory protein TetR - - - 0.00000000000000000000000000000000000000000000000000175 192.0
HFD3_k127_158296_6 Nitrate reductase delta subunit K00373 - - 0.00000000000000000000000000000000000000000000003426 175.0
HFD3_k127_158296_7 Cytochrome c - - - 0.000000000000000000000000000000000514 135.0
HFD3_k127_158296_8 Domain of unknown function (DUF4124) - - - 0.00000000002001 75.0
HFD3_k127_1591991_0 Belongs to the ClpA ClpB family K03694 - - 0.0 1216.0
HFD3_k127_1591991_1 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000000000002249 131.0
HFD3_k127_1591991_2 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) - - - 0.000000000003047 70.0
HFD3_k127_1593082_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 7.684e-245 760.0
HFD3_k127_1593082_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008174 519.0
HFD3_k127_1593082_2 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 489.0
HFD3_k127_1593082_3 Cell division protein FtsQ K03589 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006065 267.0
HFD3_k127_1603969_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 8.068e-229 720.0
HFD3_k127_1603969_1 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 289.0
HFD3_k127_1603969_3 Protein of unknown function (DUF3501) - - - 0.000158 44.0
HFD3_k127_1608215_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 1.018e-216 679.0
HFD3_k127_1608215_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 578.0
HFD3_k127_1608215_2 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006477 393.0
HFD3_k127_1608215_3 COG1064 Zn-dependent alcohol K12957 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009496 387.0
HFD3_k127_1608215_4 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 306.0
HFD3_k127_1608215_5 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000000000001602 212.0
HFD3_k127_1622145_0 Belongs to the RtcB family K14415 - 6.5.1.3 4.775e-239 756.0
HFD3_k127_1622145_2 PFAM Archease protein family (DUF101 UPF0211) K00974 - 2.7.7.72 0.000000000000000000000000000000000000002222 153.0
HFD3_k127_1627193_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000185 198.0
HFD3_k127_1637838_0 Indolepyruvate ferredoxin oxidoreductase K00179,K04090 - 1.2.7.8 8.486e-250 787.0
HFD3_k127_1637838_1 Belongs to the thiolase family K07508 - 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 592.0
HFD3_k127_1637838_2 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000009822 218.0
HFD3_k127_1637838_3 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000004406 237.0
HFD3_k127_1641451_0 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 414.0
HFD3_k127_1641451_1 Domain of unknown function (DUF1731) K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007784 376.0
HFD3_k127_1641451_2 Semialdehyde dehydrogenase, NAD binding domain K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 296.0
HFD3_k127_1647656_0 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 500.0
HFD3_k127_1647656_1 Sodium/hydrogen exchanger family K11105 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 505.0
HFD3_k127_1647656_10 response to copper ion K16915 - - 0.000000000000000000000000000000004608 143.0
HFD3_k127_1647656_11 Domain of unknown function (DUF4198) K10094 - - 0.000000000000000000000004398 111.0
HFD3_k127_1647656_12 TrkA-C domain K03455 - - 0.000000000000000000003466 96.0
HFD3_k127_1647656_13 DNA-binding transcription factor activity - - - 0.0000000000000000004639 92.0
HFD3_k127_1647656_15 Prolyl oligopeptidase K01322 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.21.26 0.0000000000003344 72.0
HFD3_k127_1647656_2 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004355 341.0
HFD3_k127_1647656_3 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003678 292.0
HFD3_k127_1647656_4 Putative MetA-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000002961 224.0
HFD3_k127_1647656_5 Belongs to the NiCoT transporter (TC 2.A.52) family K08970 - - 0.00000000000000000000000000000000000000000000000000000002117 209.0
HFD3_k127_1647656_7 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000006747 185.0
HFD3_k127_1647656_8 MOSC domain - - - 0.00000000000000000000000000000000000000000000000001238 183.0
HFD3_k127_1647656_9 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000000003499 177.0
HFD3_k127_1656866_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 565.0
HFD3_k127_1656866_1 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008626 467.0
HFD3_k127_1659835_0 COG1233 Phytoene dehydrogenase and related proteins - - - 1.372e-226 711.0
HFD3_k127_1659835_1 Pfam:DUF955 K07110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 469.0
HFD3_k127_1666449_0 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 574.0
HFD3_k127_1666449_1 Abortive infection protein K07052 - - 0.000000001941 58.0
HFD3_k127_1672308_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0 1085.0
HFD3_k127_1672308_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 4.037e-275 859.0
HFD3_k127_1672308_10 Outer membrane protein (OmpH-like) K06142 - - 0.000000000000000000000000000000000000000000000000000001486 197.0
HFD3_k127_1672308_11 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000005231 205.0
HFD3_k127_1672308_12 Endoribonuclease L-PSP K04782 - 4.2.99.21 0.00000000000000000000000000000000000000000001979 166.0
HFD3_k127_1672308_13 Belongs to the UPF0235 family K09131 - - 0.00000000000000000000000002121 127.0
HFD3_k127_1672308_2 ABC-type transport system involved in lipoprotein release permease component K09808 - - 6.224e-232 759.0
HFD3_k127_1672308_3 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 2.842e-229 735.0
HFD3_k127_1672308_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004354 563.0
HFD3_k127_1672308_5 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 485.0
HFD3_k127_1672308_6 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 436.0
HFD3_k127_1672308_7 Protein of unknown function (DUF1009) K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004179 384.0
HFD3_k127_1672308_8 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 381.0
HFD3_k127_1672308_9 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 338.0
HFD3_k127_1676267_0 fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 503.0
HFD3_k127_1676267_1 Fumarate reductase, iron-sulfur protein K00240,K00245 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006942 391.0
HFD3_k127_1676267_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 355.0
HFD3_k127_1676267_3 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000188 277.0
HFD3_k127_1676267_4 YCII-related domain K09780 - - 0.000000000000000000000000000000000000001156 149.0
HFD3_k127_1678173_0 peptidyl-tyrosine sulfation - - - 0.0 1730.0
HFD3_k127_1678173_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0 1277.0
HFD3_k127_1678173_2 glutamate--cysteine ligase K01919 - 6.3.2.2 5.518e-209 669.0
HFD3_k127_1678173_3 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008484 507.0
HFD3_k127_1678173_4 ZIP Zinc transporter K16267 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 355.0
HFD3_k127_1678173_5 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 331.0
HFD3_k127_1678173_6 - - - - 0.0000000000000000000000000000000000000006182 171.0
HFD3_k127_1678173_7 sequence-specific DNA binding K03557,K07712 GO:0000018,GO:0000229,GO:0000785,GO:0000786,GO:0000787,GO:0000789,GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008301,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016032,GO:0016070,GO:0018130,GO:0019042,GO:0019045,GO:0019046,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031421,GO:0032359,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044374,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0044815,GO:0045892,GO:0045893,GO:0045911,GO:0045934,GO:0045935,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000002179 155.0
HFD3_k127_16838_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 2.764e-208 655.0
HFD3_k127_16838_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 569.0
HFD3_k127_16838_2 Protein of unknown function (DUF3365) - - - 0.000000000000001441 84.0
HFD3_k127_1688955_0 ATP-dependent helicase HrpB K03579 - 3.6.4.13 0.0 1177.0
HFD3_k127_1688955_1 PFAM Pyridoxal-dependent decarboxylase K01593 - 4.1.1.105,4.1.1.28 1.613e-236 737.0
HFD3_k127_1688955_2 Exonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004006 297.0
HFD3_k127_1700112_0 two component, sigma54 specific, transcriptional regulator, Fis family - - - 2.058e-220 695.0
HFD3_k127_1700112_1 PFAM GGDEF domain containing protein K02488 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004074 394.0
HFD3_k127_1700112_2 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000002862 117.0
HFD3_k127_1700112_3 Tetratricopeptide repeat - - - 0.0000000000000000003111 88.0
HFD3_k127_1700112_4 Glutaredoxin K03676 - - 0.0000000000000008905 78.0
HFD3_k127_1701277_0 HAD superfamily (subfamily IG) hydrolase 5'-Nucleotidase - - - 1.007e-235 743.0
HFD3_k127_1701277_1 Insulinase (Peptidase family M16) - - - 1.294e-203 640.0
HFD3_k127_1701277_2 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 491.0
HFD3_k127_1701277_3 pseudouridine synthase activity K06177,K06179,K06180 - 5.4.99.23,5.4.99.24,5.4.99.28,5.4.99.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000108 280.0
HFD3_k127_1707067_0 Elongator protein 3, MiaB family, Radical SAM - - - 7.726e-305 942.0
HFD3_k127_1707067_1 COG1651 Protein-disulfide isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007825 300.0
HFD3_k127_1707067_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000000000000000000000000000000000007173 229.0
HFD3_k127_1707067_3 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000000001155 178.0
HFD3_k127_1709917_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000004281 221.0
HFD3_k127_1709917_1 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000003248 52.0
HFD3_k127_1713751_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 1.669e-268 832.0
HFD3_k127_1713751_1 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003583 311.0
HFD3_k127_1726536_0 Peptidase M1 membrane alanine aminopeptidase K01256,K08776 - 3.4.11.2 0.0 1098.0
HFD3_k127_1726536_1 Deoxyribodipyrimidine photo-lyase K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 588.0
HFD3_k127_1726536_2 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003693 482.0
HFD3_k127_1726536_3 PFAM Multi antimicrobial extrusion protein MatE K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 418.0
HFD3_k127_1726536_4 Major Facilitator Superfamily K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 401.0
HFD3_k127_1726536_5 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 350.0
HFD3_k127_1726536_6 Iron-storage protein K02217 - 1.16.3.2 0.000000000000000000000000000000000000000000000000000000001229 206.0
HFD3_k127_1734454_0 ABC transporter C-terminal domain K06158 - - 2.132e-284 887.0
HFD3_k127_1734454_1 Major Facilitator Superfamily K08177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006187 496.0
HFD3_k127_1734454_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 421.0
HFD3_k127_1734454_3 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002569 313.0
HFD3_k127_1734454_4 ATP-independent chaperone mediated protein folding - - - 0.00000000000000000000000000000000000198 145.0
HFD3_k127_1734454_5 energy transducer activity K03832 - - 0.00000000000000005855 93.0
HFD3_k127_1737405_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004888 565.0
HFD3_k127_1737405_1 Beta-eliminating lyase K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 556.0
HFD3_k127_1737405_2 Fructose-1,6-bisphosphatase K01622 - 3.1.3.11,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 542.0
HFD3_k127_1737405_3 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 464.0
HFD3_k127_1737405_4 Protein of unknown function (DUF938) - - - 0.0000000000000000000000000000000000000000000000000000000002525 215.0
HFD3_k127_1737405_5 PFAM Hemerythrin HHE cation binding domain K07216 - - 0.0000000000000000000000000000000000001334 146.0
HFD3_k127_1737405_6 Dodecin K09165 - - 0.000000000000000000000000002977 112.0
HFD3_k127_1737405_7 NAD(P)H-binding K01784 - 5.1.3.2 0.00000000000001888 88.0
HFD3_k127_1746218_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 496.0
HFD3_k127_1746218_1 Late embryogenesis abundant protein - - - 0.00000000000000000000000000000000000000000000000000000000000946 216.0
HFD3_k127_1749635_0 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 432.0
HFD3_k127_1749635_1 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 402.0
HFD3_k127_1749635_2 PFAM ABC transporter K01990,K01992,K09695 - - 0.0000000000000000000000000000000000000000000000001691 179.0
HFD3_k127_1749635_3 endonuclease activity - - - 0.0000002627 59.0
HFD3_k127_175915_0 metallopeptidase activity K01179 - 3.2.1.4 0.0 1072.0
HFD3_k127_175915_1 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 514.0
HFD3_k127_175915_2 esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008228 330.0
HFD3_k127_175915_3 - - - - 0.00000000000000000000000000000009027 134.0
HFD3_k127_175915_4 - - - - 0.000000000000000000000000002475 118.0
HFD3_k127_175915_5 - - - - 0.000000008029 68.0
HFD3_k127_175915_6 - - - - 0.0005731 50.0
HFD3_k127_1760351_0 nuclear chromosome segregation K02557,K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000517 511.0
HFD3_k127_1760351_1 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 420.0
HFD3_k127_1760351_2 Methylates ribosomal protein L11 K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 337.0
HFD3_k127_1760351_3 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000001414 155.0
HFD3_k127_1761869_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 1.776e-270 837.0
HFD3_k127_1761869_1 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002626 284.0
HFD3_k127_1763626_0 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 6.139e-282 878.0
HFD3_k127_1763626_1 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000003934 240.0
HFD3_k127_1763626_3 HAMP domain - - - 0.000000000000000000000000000000000000000000000006727 179.0
HFD3_k127_1763626_4 mechanosensitive ion channel activity K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.0000000000000000000000000000000000000000001107 164.0
HFD3_k127_1763626_6 - - - - 0.000000000000002221 85.0
HFD3_k127_1764468_0 PFAM aminotransferase class I and II K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009656 576.0
HFD3_k127_1764468_1 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 374.0
HFD3_k127_1764468_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00322 - 1.6.1.1 0.00000000000000000000000157 119.0
HFD3_k127_1770151_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 6.424e-243 762.0
HFD3_k127_1770151_1 Membrane protein, TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 349.0
HFD3_k127_1774705_0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 578.0
HFD3_k127_1774705_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007285 355.0
HFD3_k127_1774705_3 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000004282 133.0
HFD3_k127_1775461_0 Caspase domain - - - 0.0000000000000000000000000000000000000000000000000007209 208.0
HFD3_k127_1775461_1 AntiSigma factor - - - 0.000000000000001333 86.0
HFD3_k127_1783808_0 Sodium:solute symporter family K14393 - - 2.048e-275 853.0
HFD3_k127_1783808_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 609.0
HFD3_k127_1783808_2 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 502.0
HFD3_k127_1783808_3 PFAM Metallophosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 343.0
HFD3_k127_1783808_4 Pyridoxal-phosphate dependent enzyme K01697 - 4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000506 274.0
HFD3_k127_1783808_5 Protein of unknown function, DUF485 - - - 0.000000000000000000000000000000004885 134.0
HFD3_k127_1783808_6 Sugar (and other) transporter - - - 0.00000000000002292 72.0
HFD3_k127_1816827_0 Peptidase family M50 K11749 - - 2.925e-218 690.0
HFD3_k127_1816827_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000909 543.0
HFD3_k127_1816827_2 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 351.0
HFD3_k127_1816827_3 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 317.0
HFD3_k127_1816827_4 Glycoprotease family K01409,K14742 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004904 324.0
HFD3_k127_1816827_5 channel protein, hemolysin III family K11068 - - 0.0000000000000000000000000000000000000000000000000000000000000000001401 239.0
HFD3_k127_1816827_6 alginic acid biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000001691 219.0
HFD3_k127_1816827_7 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000002243 143.0
HFD3_k127_1816827_8 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000002068 130.0
HFD3_k127_1816827_9 GIY-YIG catalytic domain K07461 - - 0.000000000000000000000001819 106.0
HFD3_k127_1827397_0 Histidine ammonia-lyase K01745 - 4.3.1.3 1.195e-249 779.0
HFD3_k127_1853226_0 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.000000000000000000000000000000000316 136.0
HFD3_k127_1853226_1 PFAM ATP phosphoribosyltransferase - - - 0.000000000000000000000004297 114.0
HFD3_k127_1853226_2 BON domain - - - 0.00000007649 60.0
HFD3_k127_1857063_0 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 1.555e-223 700.0
HFD3_k127_1857063_1 PFAM transglutaminase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 514.0
HFD3_k127_1857063_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007527 431.0
HFD3_k127_1857063_3 Glyoxalase-like domain K05606 - 5.1.99.1 0.00000000000000000000000000000000000000000000000000000000000001398 240.0
HFD3_k127_1857063_4 OsmC-like protein K09136 - - 0.000000000000000000000000000000000000000000000004823 183.0
HFD3_k127_1867906_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 479.0
HFD3_k127_1867906_1 ABC transporter, ATP-binding protein K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 332.0
HFD3_k127_1867906_2 ABC-type transport system involved in multi-copper enzyme maturation permease component K19341 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006525 284.0
HFD3_k127_1867906_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000001752 236.0
HFD3_k127_1867906_4 Protein of unknown function (DUF2470) K07226 - - 0.0000000000000000000000000000001181 143.0
HFD3_k127_1867906_5 helix_turn_helix, Lux Regulon - - - 0.0000000000000000002346 93.0
HFD3_k127_1895817_0 4-alpha-glucanotransferase K00705 - 2.4.1.25 1.856e-230 724.0
HFD3_k127_1895817_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 2.692e-194 625.0
HFD3_k127_1895817_2 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01885,K01894 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008498 497.0
HFD3_k127_1895817_3 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 498.0
HFD3_k127_1895817_4 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) K06169 - - 0.000000000000000000000000000000000000000000000000000000000000000000004331 239.0
HFD3_k127_1895817_5 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000003466 142.0
HFD3_k127_1895817_6 phosphohistidine phosphatase, SixA K08296 - - 0.0000000000000000000000000007576 131.0
HFD3_k127_1895817_8 ATPase family associated with various cellular activities (AAA) K06027 - 3.6.4.6 0.000000000000003616 86.0
HFD3_k127_190265_0 repeat protein - - - 2.155e-261 828.0
HFD3_k127_1903261_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1090.0
HFD3_k127_1903510_0 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 350.0
HFD3_k127_1907656_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 2.236e-264 817.0
HFD3_k127_1935504_0 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 336.0
HFD3_k127_1935504_1 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006413 278.0
HFD3_k127_1935504_3 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000000000000000000000000003043 186.0
HFD3_k127_1977975_0 transmembrane signaling receptor activity K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 424.0
HFD3_k127_1977975_1 transmembrane signaling receptor activity K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006968 306.0
HFD3_k127_1977975_2 - - - - 0.0000000000000000000000000001557 126.0
HFD3_k127_1977975_3 twitching motility protein K02669 - - 0.000000000117 75.0
HFD3_k127_1981218_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.624e-237 741.0
HFD3_k127_1981218_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 2.271e-215 674.0
HFD3_k127_1981218_2 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006962 524.0
HFD3_k127_1981218_3 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 374.0
HFD3_k127_1981218_4 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002404 246.0
HFD3_k127_1981218_5 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000001088 238.0
HFD3_k127_1994912_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 8.25e-216 682.0
HFD3_k127_1994912_1 D-aminoacylase domain protein K01465,K06015 - 3.5.1.81,3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004891 492.0
HFD3_k127_1994912_2 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007934 413.0
HFD3_k127_1994912_3 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 411.0
HFD3_k127_1994912_4 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 322.0
HFD3_k127_1994912_5 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000006805 238.0
HFD3_k127_1994912_6 Histidine kinase K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000005 216.0
HFD3_k127_1994912_7 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000001822 121.0
HFD3_k127_1994912_8 PFAM Cyclic nucleotide-binding K10914 - - 0.00000000565 63.0
HFD3_k127_2003152_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005271 535.0
HFD3_k127_2003152_1 PFAM PHP domain protein K02347,K04477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 427.0
HFD3_k127_2003152_2 BON domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000304 256.0
HFD3_k127_2003152_3 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000000000000000000000000000000000000461 215.0
HFD3_k127_2003152_4 Universal stress protein - - - 0.000000000000000000000000000000000000004729 150.0
HFD3_k127_2003152_5 DNA polymerase beta thumb K02347 - - 0.000000000001103 68.0
HFD3_k127_2040593_0 Involved in arsenical resistance. Thought to form the channel of an arsenite pump - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004763 590.0
HFD3_k127_2040593_1 EXOIII K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002077 278.0
HFD3_k127_2044721_0 Serine Threonine protein kinase K12132 - 2.7.11.1 2.02e-261 842.0
HFD3_k127_2044721_1 4-Oxalocrotonate Tautomerase - - - 0.00000000000000000000000000000000000000000000000000000000002885 209.0
HFD3_k127_2044721_2 - - - - 0.0000000000000000000000001919 111.0
HFD3_k127_2044823_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 1.408e-236 738.0
HFD3_k127_2044823_1 PFAM glycoside hydrolase, family 1 K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 418.0
HFD3_k127_2044823_2 Phospholipase/Carboxylesterase K06999 - - 0.000000000000000000000000000000000000000000000000000000003903 224.0
HFD3_k127_2044823_3 membrane - - - 0.0000000000000000000000000000000000000284 149.0
HFD3_k127_2077135_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 1.176e-311 964.0
HFD3_k127_2077135_1 SMART Elongator protein 3 MiaB NifB - - - 6.041e-196 648.0
HFD3_k127_2077135_2 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 493.0
HFD3_k127_2077135_3 Transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 412.0
HFD3_k127_2077135_4 PFAM Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006787 258.0
HFD3_k127_2077135_5 Tannase and feruloyl esterase - - - 0.00000000000000000000000000000000000000000000000000000000002568 224.0
HFD3_k127_2077135_6 energy transducer activity K03832 - - 0.000000000000000000000000000000000000000006997 178.0
HFD3_k127_2077135_8 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000001493 146.0
HFD3_k127_2079647_0 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 594.0
HFD3_k127_2079647_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009143 371.0
HFD3_k127_2079647_2 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000001193 123.0
HFD3_k127_2079647_3 - - - - 0.0001318 46.0
HFD3_k127_2114580_0 nitrite reductase [NAD(P)H] activity K00493,K07408,K15762 - 1.14.14.1 2.292e-197 632.0
HFD3_k127_2133840_0 Periplasmic copper-binding protein (NosD) K07218 - - 4.136e-196 620.0
HFD3_k127_2133840_1 ABC transporter K01990,K19340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008601 402.0
HFD3_k127_21844_0 Ser-tRNA(Ala) hydrolase activity K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 482.0
HFD3_k127_21844_1 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 313.0
HFD3_k127_21844_2 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000006711 199.0
HFD3_k127_21844_3 Chitobiase/beta-hexosaminidase C-terminal domain - - - 0.000000000000000000000000000000000000000222 173.0
HFD3_k127_21844_4 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131,K06915 - - 0.00000000000000000000003412 117.0
HFD3_k127_21844_5 PFAM Smr protein MutS2 - - - 0.0000000000000003431 79.0
HFD3_k127_21844_6 - - - - 0.0004307 52.0
HFD3_k127_2193250_0 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 1.453e-230 737.0
HFD3_k127_2193250_1 Ferric uptake regulator family K03711 - - 0.00000000000000000000000000000000000000000000000000000000000001365 221.0
HFD3_k127_2215069_0 General secretion pathway protein F K02455,K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 558.0
HFD3_k127_2215069_1 general secretion pathway protein G K02456 - - 0.0000000000000000000000000001885 132.0
HFD3_k127_2217491_0 FHA domain - - - 3.776e-248 785.0
HFD3_k127_2217491_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000272 193.0
HFD3_k127_2217641_0 Phosphoglucose isomerase K01810 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 5.3.1.9 2.157e-276 857.0
HFD3_k127_2217641_1 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 532.0
HFD3_k127_2217641_10 Prolyl oligopeptidase family - - - 0.00000000000003874 81.0
HFD3_k127_2217641_2 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004114 533.0
HFD3_k127_2217641_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 472.0
HFD3_k127_2217641_4 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 389.0
HFD3_k127_2217641_5 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006928 385.0
HFD3_k127_2217641_6 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 325.0
HFD3_k127_2217641_7 metal cluster binding K06940 - - 0.000000000000000000000000000000000000000000000000000000000000000000006817 240.0
HFD3_k127_2217641_8 - - - - 0.00000000000000000000000000000000000004693 153.0
HFD3_k127_2217641_9 MazG-like family - - - 0.00000000000000000000001913 111.0
HFD3_k127_2232037_0 Metallopeptidase family M24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009646 594.0
HFD3_k127_2232037_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006785 561.0
HFD3_k127_2232037_10 - - - - 0.000000000000000000000000000000000000002297 156.0
HFD3_k127_2232037_11 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000001489 153.0
HFD3_k127_2232037_12 - - - - 0.00000000008584 74.0
HFD3_k127_2232037_13 Transposase - - - 0.00000002157 56.0
HFD3_k127_2232037_14 - - - - 0.00000003757 65.0
HFD3_k127_2232037_16 - - - - 0.0001942 53.0
HFD3_k127_2232037_2 PFAM ATP-binding region, ATPase domain protein K02668,K07708,K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 495.0
HFD3_k127_2232037_3 Bacterial regulatory protein, Fis family K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007091 392.0
HFD3_k127_2232037_4 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 337.0
HFD3_k127_2232037_6 Doxx family K15977 - - 0.000000000000000000000000000000000000000000000000001069 190.0
HFD3_k127_2232037_7 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000001156 209.0
HFD3_k127_2232037_9 - - - - 0.00000000000000000000000000000000000000000003932 172.0
HFD3_k127_2238280_0 Dienelactone hydrolase family - - - 1.236e-262 824.0
HFD3_k127_2238280_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000009401 217.0
HFD3_k127_2253817_0 Von Willebrand factor type A K07114 - - 4.789e-276 871.0
HFD3_k127_2253817_1 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 463.0
HFD3_k127_2253817_2 Alpha/beta hydrolase family K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 433.0
HFD3_k127_2253817_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008473 432.0
HFD3_k127_2253817_4 Formate dehydrogenase N, transmembrane K00124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 336.0
HFD3_k127_2253817_5 formate dehydrogenase K00127 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007815 253.0
HFD3_k127_2253817_6 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000006928 251.0
HFD3_k127_2253817_7 Necessary for formate dehydrogenase activity K02380 - - 0.00000000000000000000000000000000000000000000000000000000001086 228.0
HFD3_k127_2253817_8 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000002479 212.0
HFD3_k127_2253817_9 COG3794 Plastocyanin - - - 0.00001002 58.0
HFD3_k127_2259334_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0 1039.0
HFD3_k127_2259334_1 Pyruvate flavodoxin ferredoxin K00174 - 1.2.7.11,1.2.7.3 7.95e-322 994.0
HFD3_k127_2259334_10 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000000000000000000000001963 169.0
HFD3_k127_2259334_11 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000000000000000000000000000000002548 148.0
HFD3_k127_2259334_12 Rieske [2Fe-2S] domain K00363 - 1.7.1.15 0.0000000000000000000000000000537 130.0
HFD3_k127_2259334_13 - K00712 - 2.4.1.52 0.000000000000000000000001224 107.0
HFD3_k127_2259334_2 FAD linked oxidases, C-terminal domain K00102,K00104 - 1.1.2.4,1.1.3.15 5.422e-230 738.0
HFD3_k127_2259334_3 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 590.0
HFD3_k127_2259334_4 Sigma-54 interaction domain K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 423.0
HFD3_k127_2259334_5 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 310.0
HFD3_k127_2259334_6 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004035 265.0
HFD3_k127_2259334_7 GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000002195 253.0
HFD3_k127_2259334_8 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000000000000001796 225.0
HFD3_k127_2259334_9 histidine kinase, HAMP - - - 0.00000000000000000000000000000000000000000000002563 189.0
HFD3_k127_2305626_0 repeat protein - - - 1.221e-213 694.0
HFD3_k127_2328404_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1446.0
HFD3_k127_2328404_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 610.0
HFD3_k127_2328404_2 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 405.0
HFD3_k127_2328404_3 acid phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004966 399.0
HFD3_k127_2328404_5 - - - - 0.0000000000000002908 93.0
HFD3_k127_2340933_0 asparaginyl-tRNA synthetase K01893 - 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 604.0
HFD3_k127_2340933_1 Membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.0000000000002621 74.0
HFD3_k127_2349609_0 two component, sigma54 specific, transcriptional regulator, Fis family - - - 1.125e-232 728.0
HFD3_k127_2349609_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 486.0
HFD3_k127_2349609_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003602 274.0
HFD3_k127_2349609_3 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000001893 166.0
HFD3_k127_2359851_0 NAD(P)H quinone oxidoreductase, PIG3 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008543 529.0
HFD3_k127_2359851_1 OPT oligopeptide transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 520.0
HFD3_k127_2366367_0 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000472 342.0
HFD3_k127_2366367_1 Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007006 315.0
HFD3_k127_2366367_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 296.0
HFD3_k127_2366367_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000003738 263.0
HFD3_k127_2366367_4 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000162 143.0
HFD3_k127_2367516_0 Domain of Unknown Function with PDB structure (DUF3857) - - - 8.877e-257 814.0
HFD3_k127_2373478_0 NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 517.0
HFD3_k127_2373478_1 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 475.0
HFD3_k127_2373478_2 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 291.0
HFD3_k127_2373478_3 Ribbon-helix-helix domain - - - 0.0000000000000000000000000004554 114.0
HFD3_k127_2373478_4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000241 100.0
HFD3_k127_2395552_0 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005936 373.0
HFD3_k127_2395552_2 Protein of unknown function (DUF420) K08976 - - 0.000000000000000000000000000000000000000000000000001505 192.0
HFD3_k127_2395552_3 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0003671 48.0
HFD3_k127_2398424_0 Bacterial transcriptional activator domain - - - 1.737e-309 988.0
HFD3_k127_2398424_1 Peptidase, M61 - - - 8.453e-264 827.0
HFD3_k127_2398424_2 alcohol dehydrogenase K18012 - 1.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 527.0
HFD3_k127_2398424_3 endonuclease activity K07451 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 494.0
HFD3_k127_2398424_4 Histidine kinase - - - 0.00000000000007415 85.0
HFD3_k127_2398424_5 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.00000000006204 63.0
HFD3_k127_2398424_6 - - - - 0.000001651 55.0
HFD3_k127_2412426_0 TonB dependent receptor K02014 - - 8.716e-217 695.0
HFD3_k127_2416186_0 Serine Threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 345.0
HFD3_k127_2416186_1 TPR repeat - - - 0.000000000000000000000000000000000000000000000000001927 193.0
HFD3_k127_2416186_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000001597 141.0
HFD3_k127_2416915_0 long-chain fatty acid transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 497.0
HFD3_k127_2437717_0 Acid phosphatase homologues - - - 0.0000000000000000000000000000000000000000000000007397 183.0
HFD3_k127_2437717_1 long-chain fatty acid transporting porin activity - - - 0.0000117 57.0
HFD3_k127_2453988_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1957.0
HFD3_k127_2453988_1 TIGRFAM cytochrome C family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 539.0
HFD3_k127_2453988_2 Serine Threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 454.0
HFD3_k127_2453988_3 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001752 268.0
HFD3_k127_2453988_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005254 255.0
HFD3_k127_2453988_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000008925 221.0
HFD3_k127_2453988_6 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000000002709 152.0
HFD3_k127_2453988_7 TfoX N-terminal domain K07343 - - 0.00000000000000000004389 105.0
HFD3_k127_2453988_8 Putative zinc-finger - - - 0.00000002572 65.0
HFD3_k127_2468454_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 6.641e-196 618.0
HFD3_k127_2468454_1 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 574.0
HFD3_k127_2468454_2 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 434.0
HFD3_k127_2468454_3 Belongs to the SUA5 family K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 348.0
HFD3_k127_2468454_4 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001806 262.0
HFD3_k127_2538568_0 B12 binding domain - - - 8.96e-197 627.0
HFD3_k127_2538568_1 Di-haem oxidoreductase, putative peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 553.0
HFD3_k127_2538568_2 Fatty acid desaturase K00508 - 1.14.19.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 424.0
HFD3_k127_2538568_3 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000959 281.0
HFD3_k127_2538568_4 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000001029 164.0
HFD3_k127_2538568_5 cold-shock protein K03704 - - 0.000000000000000000000000000000000005823 139.0
HFD3_k127_2538568_6 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.000000000000000000000000000000373 139.0
HFD3_k127_2539686_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 523.0
HFD3_k127_2539686_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008156 451.0
HFD3_k127_2539686_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000188 289.0
HFD3_k127_2542772_0 Peptidogalycan biosysnthesis/recognition K09919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005587 527.0
HFD3_k127_2542772_1 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 387.0
HFD3_k127_2542772_2 PFAM Thiamine pyrophosphate K00170,K00187 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 323.0
HFD3_k127_2542772_3 Protein of unknown function (DUF2845) - - - 0.000000000000000000000000000000000000005646 161.0
HFD3_k127_2542772_4 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000534 110.0
HFD3_k127_2542772_5 HI0933-like protein - - - 0.00000000000000000000000172 110.0
HFD3_k127_2542772_6 ketosteroid isomerase - - - 0.00000000003734 74.0
HFD3_k127_2544385_0 - - - - 2.638e-305 947.0
HFD3_k127_2544385_1 Pyridine nucleotide-disulphide oxidoreductase K00529 - 1.18.1.3 1.483e-208 655.0
HFD3_k127_2544385_10 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 289.0
HFD3_k127_2544385_11 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000000002204 217.0
HFD3_k127_2544385_12 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000000000000000000000000000000000002071 204.0
HFD3_k127_2544385_13 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity - - - 0.0000000000000000000000000000000000000000000002252 173.0
HFD3_k127_2544385_14 DoxX-like family - - - 0.000000000000000000000000000000000000000005609 159.0
HFD3_k127_2544385_15 rhodanese-related sulfurtransferase - - - 0.00000000000000000000000000000000000000003813 165.0
HFD3_k127_2544385_16 DGC domain - - - 0.0000000000000000000000000000000001441 141.0
HFD3_k127_2544385_17 OsmC-like protein - - - 0.00000000000000000000000000003464 128.0
HFD3_k127_2544385_18 Nucleic acid binding OB-fold tRNA helicase-type - - - 0.0000000000000000000000000000896 123.0
HFD3_k127_2544385_19 DGC domain - - - 0.0000000000000000000002375 108.0
HFD3_k127_2544385_2 Aminotransferase class I and II K14267 - 2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 546.0
HFD3_k127_2544385_20 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 - - 0.000000000000000000001535 106.0
HFD3_k127_2544385_21 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000001872 49.0
HFD3_k127_2544385_3 Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 488.0
HFD3_k127_2544385_4 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 402.0
HFD3_k127_2544385_5 Sphingolipid Delta4-desaturase (DES) K04712 - 1.14.18.5,1.14.19.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 354.0
HFD3_k127_2544385_6 PFAM ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 334.0
HFD3_k127_2544385_7 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008758 346.0
HFD3_k127_2544385_8 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 298.0
HFD3_k127_2544385_9 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 308.0
HFD3_k127_2544845_0 Glycosyl transferase family 21 - - - 1.31e-234 734.0
HFD3_k127_2551027_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 572.0
HFD3_k127_2551027_1 Class II Aldolase and Adducin N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008412 339.0
HFD3_k127_2557564_0 Sugar ABC transporter permease K10109,K15770,K15771 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 574.0
HFD3_k127_2557564_1 Binding-protein-dependent transport system inner membrane component K10110,K15772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001164 281.0
HFD3_k127_2560833_0 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 1.529e-276 863.0
HFD3_k127_2560833_1 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00112 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 347.0
HFD3_k127_2560833_2 Tautomerase enzyme - - - 0.000000000000000000000000000000000000000000000007006 176.0
HFD3_k127_2560833_3 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.00000000000000000000000000000000000007898 141.0
HFD3_k127_2561356_0 Domain of unknown function (DUF3372) K01200 - 3.2.1.41 0.0 1079.0
HFD3_k127_2561356_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 282.0
HFD3_k127_2562900_0 Penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 8.596e-295 922.0
HFD3_k127_2562900_1 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 4.733e-225 717.0
HFD3_k127_2562900_10 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000009808 147.0
HFD3_k127_2562900_2 Forkhead associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005428 508.0
HFD3_k127_2562900_3 Phosphotransferase enzyme family K02204 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 452.0
HFD3_k127_2562900_4 TPR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 426.0
HFD3_k127_2562900_5 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 289.0
HFD3_k127_2562900_6 protein trimerization - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001066 289.0
HFD3_k127_2562900_7 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.000000000000000000000000000000000000000000000004882 179.0
HFD3_k127_2562900_9 - - - - 0.00000000000000000000000000000000000005406 147.0
HFD3_k127_2565854_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 6.639e-305 944.0
HFD3_k127_2570946_0 epimerase dehydratase K01710,K01784 - 4.2.1.46,5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 497.0
HFD3_k127_2570946_1 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007495 451.0
HFD3_k127_2570946_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 435.0
HFD3_k127_2570946_3 UDP binding domain K02472 - 1.1.1.336 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 400.0
HFD3_k127_2570946_4 TPR repeat-containing protein - - - 0.00000000000000000000000000000000000000000001675 186.0
HFD3_k127_2570946_5 - - - - 0.000000000000000000000000001353 129.0
HFD3_k127_2586834_0 Capsule assembly protein Wzi - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 316.0
HFD3_k127_2586834_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000005062 71.0
HFD3_k127_2591822_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 6.081e-277 869.0
HFD3_k127_2604092_0 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 2.098e-250 792.0
HFD3_k127_2604092_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 590.0
HFD3_k127_2604092_2 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 509.0
HFD3_k127_2604092_3 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004275 385.0
HFD3_k127_2604092_4 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005725 319.0
HFD3_k127_2604092_5 TIGRFAM CoA-substrate-specific enzyme activase - - - 0.00000000000000000000000000000000000000000000000000000003556 220.0
HFD3_k127_2604092_6 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000251 203.0
HFD3_k127_2604092_7 TIGRFAM CoA-substrate-specific enzyme activase - - - 0.0000000000000000000000000000001765 144.0
HFD3_k127_2604092_8 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0000000000000000000000000000006229 126.0
HFD3_k127_2616552_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.0 1124.0
HFD3_k127_2616552_1 ABC transporter K06147,K06148 - - 3.777e-286 889.0
HFD3_k127_2616552_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000831 383.0
HFD3_k127_2616552_3 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009258 359.0
HFD3_k127_2616552_4 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000002568 227.0
HFD3_k127_2616552_5 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.0000000000000006415 79.0
HFD3_k127_2616593_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 2.948e-204 655.0
HFD3_k127_2616593_1 DNA helicase K03654 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 444.0
HFD3_k127_2616593_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003331 323.0
HFD3_k127_2616593_3 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000693 310.0
HFD3_k127_2616593_4 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007666 276.0
HFD3_k127_2616593_5 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000001957 268.0
HFD3_k127_261852_0 Proton-conducting membrane transporter K00342 - 1.6.5.3 2.555e-294 912.0
HFD3_k127_261852_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 8.381e-225 734.0
HFD3_k127_261852_2 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.00000001333 56.0
HFD3_k127_2628887_0 Proton-conducting membrane transporter K12137 - - 2.371e-213 688.0
HFD3_k127_2628887_1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 7.471e-207 676.0
HFD3_k127_2628887_2 Proton-conducting membrane transporter K12141 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 576.0
HFD3_k127_2628887_3 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 368.0
HFD3_k127_2628887_4 hydrogenase 4 membrane K12140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003095 289.0
HFD3_k127_2628887_5 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.00000000000000000000000000000000000000000001201 166.0
HFD3_k127_2628887_6 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000006116 88.0
HFD3_k127_2633762_0 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 0.0 1801.0
HFD3_k127_2633762_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000495 399.0
HFD3_k127_2633762_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007895 247.0
HFD3_k127_2633762_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000004132 198.0
HFD3_k127_2638146_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0 1028.0
HFD3_k127_2638146_1 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 1.777e-311 960.0
HFD3_k127_2638146_10 Protein similar to CwfJ C-terminus 1 K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000000000000000000000000000005976 248.0
HFD3_k127_2638146_11 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.000000000000000000000000000000000000000000000000000000000000000000003264 240.0
HFD3_k127_2638146_12 Glutathione peroxidase - - - 0.000000000000000002513 94.0
HFD3_k127_2638146_13 PilZ domain - - - 0.0000000000001377 78.0
HFD3_k127_2638146_2 histidyl-tRNA synthetase K01892 - 6.1.1.21 5.774e-210 660.0
HFD3_k127_2638146_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 511.0
HFD3_k127_2638146_4 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007456 482.0
HFD3_k127_2638146_5 signal peptide peptidase SppA, 36K type K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006369 441.0
HFD3_k127_2638146_6 Belongs to the phosphatidylserine decarboxylase family K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004857 426.0
HFD3_k127_2638146_7 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 406.0
HFD3_k127_2638146_8 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 323.0
HFD3_k127_2638146_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003139 297.0
HFD3_k127_2647921_0 PFAM SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006485 248.0
HFD3_k127_2647921_2 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000000000000000000000000000000001033 216.0
HFD3_k127_2647921_3 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000003059 180.0
HFD3_k127_2647921_4 Bacterial membrane protein, YfhO - - - 0.000000000000000000000000000000000001848 160.0
HFD3_k127_2647921_5 Protein of unknown function (DUF2846) - - - 0.000000000000000000000006246 107.0
HFD3_k127_2674815_0 HAD-hyrolase-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 447.0
HFD3_k127_2674815_1 Butirosin biosynthesis protein H, N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 403.0
HFD3_k127_2674815_2 Short-chain dehydrogenase reductase SDR K00059,K00076,K00216,K03366,K13774,K18337 - 1.1.1.100,1.1.1.159,1.1.1.173,1.1.1.304,1.1.1.377,1.1.1.378,1.1.1.76,1.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 390.0
HFD3_k127_2674815_3 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 303.0
HFD3_k127_2674815_4 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001712 261.0
HFD3_k127_2674815_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000003864 229.0
HFD3_k127_2674815_6 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000000000000000008125 199.0
HFD3_k127_2674815_7 Ferredoxin - - - 0.000000000000000000000000000000000000000000000105 173.0
HFD3_k127_2675231_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00334,K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 602.0
HFD3_k127_2675231_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000007176 212.0
HFD3_k127_2675231_3 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000009813 178.0
HFD3_k127_2675231_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000002042 119.0
HFD3_k127_2675969_0 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 8.754e-224 703.0
HFD3_k127_2675969_1 aspartate glutamate uridylate kinase K00928 - 2.7.2.4 2.643e-213 686.0
HFD3_k127_2675969_2 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 507.0
HFD3_k127_2675969_3 involved in molybdopterin and THIamine biosynthesis family 1 K03148,K21029,K22132 GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016829,GO:0016835,GO:0016836,GO:0030955,GO:0031402,GO:0031420,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0061503,GO:0061504,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.7.7.73,2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 370.0
HFD3_k127_2675969_4 Beta propeller domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001389 299.0
HFD3_k127_2675969_5 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000841 271.0
HFD3_k127_2675969_6 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000384 246.0
HFD3_k127_2684029_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.32e-287 899.0
HFD3_k127_2684029_1 PFAM peptidase M3A and M3B thimet oligopeptidase F K08602 - - 1.202e-240 759.0
HFD3_k127_2684029_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.2.1.33,4.2.1.35 1.52e-213 689.0
HFD3_k127_2684029_3 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007707 587.0
HFD3_k127_2684029_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000859 264.0
HFD3_k127_2684029_5 - - - - 0.00000000000000000000000000000000000001464 151.0
HFD3_k127_2684029_6 Cold-shock protein K03704 - - 0.0000000000000000000000000000000001449 133.0
HFD3_k127_2684029_8 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0000000000002777 70.0
HFD3_k127_2706529_0 Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007925 471.0
HFD3_k127_2706529_1 4Fe-4S dicluster domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 309.0
HFD3_k127_2706529_2 Glycine cleavage H-protein - - - 0.0000000000000000000000000000000000000000000000000000000005583 211.0
HFD3_k127_2706529_3 Glycine cleavage H-protein - - - 0.00000000000000000000000000000000002424 145.0
HFD3_k127_2706529_5 PFAM response regulator receiver K07713 - - 0.0000000001804 61.0
HFD3_k127_2712908_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009944 603.0
HFD3_k127_2712908_1 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity K12583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 572.0
HFD3_k127_2712908_2 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 301.0
HFD3_k127_2712908_3 Pectinacetylesterase - - - 0.00000000000000000000000000000000000000000000000000000000001143 223.0
HFD3_k127_2725317_0 Peptidase family M3 K01284 - 3.4.15.5 0.0 1043.0
HFD3_k127_2725317_1 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 5.203e-198 631.0
HFD3_k127_2725317_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005561 453.0
HFD3_k127_2725317_3 Belongs to the MenA family. Type 1 subfamily K02548 GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046428,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 428.0
HFD3_k127_2725317_4 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000014 295.0
HFD3_k127_2725317_5 Carbon monoxide dehydrogenase subunit G (CoxG) - - - 0.000000000000000000000000000000000000000004347 164.0
HFD3_k127_2725317_6 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000001164 87.0
HFD3_k127_2729281_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 609.0
HFD3_k127_2729281_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000001317 256.0
HFD3_k127_2729281_2 3-hydroxyacyl-CoA dehydrogenase NAD-binding K07516 - 1.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000004855 231.0
HFD3_k127_2753847_0 response regulator K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006554 341.0
HFD3_k127_2753847_1 Appr-1'-p processing enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000006818 229.0
HFD3_k127_2754036_0 Protein of unknown function (DUF455) K11529 - 2.7.1.165 0.000000000000003534 88.0
HFD3_k127_2754036_1 Protein of unknown function (DUF455) K11529 - 2.7.1.165 0.0000000000001222 81.0
HFD3_k127_2754036_2 asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000004311 79.0
HFD3_k127_2754036_4 Protein of unknown function (DUF455) - - - 0.0000000001166 72.0
HFD3_k127_2754036_5 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.00002046 57.0
HFD3_k127_2754455_0 Heat shock 70 kDa protein K04043 - - 1.74e-286 886.0
HFD3_k127_2754455_1 Sterol carrier protein - - - 0.00000000000000000000000000000000000001239 166.0
HFD3_k127_2754455_2 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.000000000000000000003135 95.0
HFD3_k127_2778893_0 Aminotransferase K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004745 407.0
HFD3_k127_2778893_4 Stage II sporulation protein - - - 0.00000000000000000162 94.0
HFD3_k127_2778893_5 Stage II sporulation protein M - - - 0.0005913 44.0
HFD3_k127_2784844_0 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 336.0
HFD3_k127_2784844_1 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004371 243.0
HFD3_k127_2784844_2 heat shock protein binding - - - 0.0000000000000000000000000000000000000002254 153.0
HFD3_k127_2814193_0 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006079 542.0
HFD3_k127_2814193_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 477.0
HFD3_k127_2814193_2 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 333.0
HFD3_k127_2814193_3 cyclic nucleotide-binding K10914 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 303.0
HFD3_k127_2814193_4 translation initiation factor activity - - - 0.0000000000000000000000000000000000000000000008177 177.0
HFD3_k127_2814193_5 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000004296 147.0
HFD3_k127_2820308_0 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 302.0
HFD3_k127_2820308_1 Response regulator, receiver - - - 0.0000000000000000000000000000000000005091 142.0
HFD3_k127_2820308_2 HD domain - - - 0.000000000000000000004351 99.0
HFD3_k127_2820308_3 iron ion homeostasis - - - 0.0000000003583 67.0
HFD3_k127_2820308_4 FecR protein - - - 0.000007929 58.0
HFD3_k127_2826984_0 Outer membrane receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003885 592.0
HFD3_k127_2826984_1 MotA TolQ ExbB proton channel K03561,K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009796 384.0
HFD3_k127_2826984_2 energy transducer activity K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006302 262.0
HFD3_k127_2826984_3 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000003874 250.0
HFD3_k127_2826984_4 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.00000000000000000000000000000000000000000000000004377 181.0
HFD3_k127_2826984_5 biopolymer transport protein K03559,K03560 - - 0.0000000000000000000000000000000000000000000000002199 201.0
HFD3_k127_2834273_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 530.0
HFD3_k127_2834273_1 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 417.0
HFD3_k127_2834273_2 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007013 435.0
HFD3_k127_2834273_3 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 325.0
HFD3_k127_2834273_4 hydrolase activity, acting on ester bonds K07051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 296.0
HFD3_k127_2834273_5 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000001235 190.0
HFD3_k127_2834273_6 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000001365 129.0
HFD3_k127_2834273_7 Methyl-transferase K00575 - 2.1.1.80 0.00000000000000000000001617 104.0
HFD3_k127_2834273_8 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.0000000000000000000004966 96.0
HFD3_k127_2834273_9 Receptor K02014 - - 0.0003572 53.0
HFD3_k127_2840143_0 histidine kinase HAMP region domain protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 520.0
HFD3_k127_2840143_1 Response regulator receiver domain K03413 - - 0.000000000000000000000000000000000000000000000000000000000000000008826 226.0
HFD3_k127_2840143_2 chemotaxis K02659,K03408 - - 0.0000000000000000000000000000000000000000002526 178.0
HFD3_k127_2840143_3 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.00000000000000000000000001065 122.0
HFD3_k127_2844142_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 525.0
HFD3_k127_2844142_1 Transcriptional regulator, LysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 389.0
HFD3_k127_2844142_2 Bacterial regulatory proteins, tetR family K16137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003778 263.0
HFD3_k127_2844142_3 XdhC Rossmann domain K07402 - - 0.00000000000000000000000000000000000000000000000000000000000009683 228.0
HFD3_k127_2844142_4 MobA-Related Protein K07141 - 2.7.7.76 0.00000000000000000000000000000000000000000000000000000000471 206.0
HFD3_k127_2844142_5 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000004922 176.0
HFD3_k127_2844142_6 Carbon monoxide dehydrogenase subunit G (CoxG) - - - 0.00000000000000000000000000000000000000002601 156.0
HFD3_k127_2844142_7 XdhC and CoxI family - - - 0.00000000000000000000000000000000000002061 155.0
HFD3_k127_2844142_8 NifU-like N terminal domain K04488 - - 0.000000000000000000000000002168 126.0
HFD3_k127_2877769_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000666 427.0
HFD3_k127_2877769_1 Domain present in PSD-95, Dlg, and ZO-1/2. K02452 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009817 396.0
HFD3_k127_2877769_2 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000000000000001154 146.0
HFD3_k127_2877769_3 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000003191 74.0
HFD3_k127_2877769_4 domain, Protein - - - 0.00000000001423 74.0
HFD3_k127_2884541_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 5.589e-272 842.0
HFD3_k127_2884541_1 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 8.731e-211 659.0
HFD3_k127_2884541_2 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 334.0
HFD3_k127_2884541_3 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009477 297.0
HFD3_k127_2884541_4 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000135 293.0
HFD3_k127_2884541_5 Staphylococcal nuclease homologue - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001577 273.0
HFD3_k127_2884541_6 NADPH-dependent FMN reductase K19784 - - 0.000000000000000000000000000000000000000000000000000000000000001412 223.0
HFD3_k127_2884541_7 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000001035 169.0
HFD3_k127_2884541_8 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.0000000000000000000000000000000000002978 141.0
HFD3_k127_2918522_0 Methyltransferase domain - - - 8.169e-243 759.0
HFD3_k127_2918522_1 UDP binding domain K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009847 611.0
HFD3_k127_2918522_3 - - - - 0.000001323 57.0
HFD3_k127_2927411_0 Von Willebrand factor type A K07114 - - 0.00000000000000000000000000000000000000000000000000000003498 218.0
HFD3_k127_2927411_1 Von Willebrand factor type A K07114 - - 0.00000000000000000000000000000000000000000003951 166.0
HFD3_k127_2927411_2 Von Willebrand factor type A K07114 - - 0.000000000000000000000000000000001764 135.0
HFD3_k127_2938457_0 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 6.752e-252 790.0
HFD3_k127_2938457_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 364.0
HFD3_k127_2938457_2 acetolactate synthase K01576,K01652 - 2.2.1.6,4.1.1.7 0.0000000000000000000000000000000002027 153.0
HFD3_k127_2959567_0 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 503.0
HFD3_k127_2959567_1 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000006833 95.0
HFD3_k127_2959567_2 Peptidase family M48 - - - 0.000000000000003632 89.0
HFD3_k127_2986201_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 471.0
HFD3_k127_2986201_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000004167 264.0
HFD3_k127_2986201_2 thiolester hydrolase activity K06889 - - 0.0000000000000000000000000000000000000000000000000001378 196.0
HFD3_k127_2986201_3 Protein of unknown function (DUF456) K09793 - - 0.000000000000000000000000000000000000000000000005459 179.0
HFD3_k127_2986201_4 SnoaL-like domain - - - 0.00000000000000000000000000000001057 138.0
HFD3_k127_2986201_5 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00003364 46.0
HFD3_k127_3042357_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1186.0
HFD3_k127_3042357_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0000000001539 62.0
HFD3_k127_3047452_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 1.314e-271 842.0
HFD3_k127_3047452_1 - - - - 0.0000000000000000000000000000000000152 145.0
HFD3_k127_3047452_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.000000000000000000000000000002663 121.0
HFD3_k127_3047452_3 - - - - 0.0000000000000000000000000005464 123.0
HFD3_k127_3047452_4 - - - - 0.0000000000000000000000002643 116.0
HFD3_k127_3047452_5 - - - - 0.00000000000000000000007858 111.0
HFD3_k127_3048957_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002075 241.0
HFD3_k127_3048957_2 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000002269 134.0
HFD3_k127_3048957_3 - - - - 0.00000001323 65.0
HFD3_k127_3064123_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 3.364e-293 949.0
HFD3_k127_3064123_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 4.333e-244 812.0
HFD3_k127_3064123_2 pfam abc1 K03688 - - 5.07e-234 737.0
HFD3_k127_3064123_3 Universal stress protein family - - - 0.00000001114 65.0
HFD3_k127_3064123_4 - - - - 0.00001359 48.0
HFD3_k127_3078667_0 - - - - 0.00000000006177 75.0
HFD3_k127_3078667_1 Carboxypeptidase regulatory-like domain - - - 0.00005743 57.0
HFD3_k127_3085564_0 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 375.0
HFD3_k127_3085564_1 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006536 356.0
HFD3_k127_3085564_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000973 268.0
HFD3_k127_3085564_3 Chromate transporter K07240 - - 0.00000003367 59.0
HFD3_k127_3090394_0 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006744 521.0
HFD3_k127_3090394_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005549 274.0
HFD3_k127_3090394_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0005911 49.0
HFD3_k127_3098837_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004852 572.0
HFD3_k127_3098837_1 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 531.0
HFD3_k127_3098837_2 Coenzyme A transferase K01029 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009558 330.0
HFD3_k127_3098837_3 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 304.0
HFD3_k127_3098837_4 PFAM ABC transporter related K05776 - - 0.0000000000000000000000000000000000000000000000000000004689 199.0
HFD3_k127_3098837_5 Sigma-70 region 2 - - - 0.00000000000000000000000000000000000000000000000000002679 204.0
HFD3_k127_3098837_6 PilZ domain - - - 0.00000000000000000000000000000000000000004013 169.0
HFD3_k127_3098837_7 glyoxalase III activity - - - 0.00000000000000000004987 103.0
HFD3_k127_3105232_0 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 2.802e-230 724.0
HFD3_k127_3105232_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 396.0
HFD3_k127_3105232_2 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 297.0
HFD3_k127_3105232_3 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000691 282.0
HFD3_k127_3105232_4 Benzoyl-CoA reductase subunit K04115 - 1.3.7.8 0.0000000000000002691 80.0
HFD3_k127_3110204_0 exonuclease activity K16899 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 337.0
HFD3_k127_3110204_1 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000000000000000000001919 233.0
HFD3_k127_3110204_2 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000000000000000000000000000000000000000003843 177.0
HFD3_k127_3110204_3 PFAM DoxX family protein - - - 0.00000000000000000000000000000000000000166 160.0
HFD3_k127_3112103_0 Aminotransferase - - - 1.345e-222 697.0
HFD3_k127_3112103_1 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 442.0
HFD3_k127_3112103_2 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 296.0
HFD3_k127_3112103_3 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000000003164 223.0
HFD3_k127_3112103_4 Protein of unknown function (DUF3761) - - - 0.0000001691 59.0
HFD3_k127_3113469_0 Class III cytochrome C family - - - 4.603e-243 767.0
HFD3_k127_3113469_1 cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 516.0
HFD3_k127_3113469_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002618 256.0
HFD3_k127_3113469_11 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000005581 242.0
HFD3_k127_3113469_12 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000003476 219.0
HFD3_k127_3113469_13 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000001943 227.0
HFD3_k127_3113469_14 Putative bacterial lipoprotein (DUF799) - - - 0.00000000000000000000000000000000000000000000000000002584 203.0
HFD3_k127_3113469_16 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000003093 75.0
HFD3_k127_3113469_2 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007514 429.0
HFD3_k127_3113469_3 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 381.0
HFD3_k127_3113469_4 PPIC-type PPIASE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 361.0
HFD3_k127_3113469_5 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007421 342.0
HFD3_k127_3113469_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004598 330.0
HFD3_k127_3113469_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006263 292.0
HFD3_k127_3113469_8 TIGRFAM cytochrome C family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001777 284.0
HFD3_k127_3113469_9 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006541 281.0
HFD3_k127_31304_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 4.073e-229 721.0
HFD3_k127_31304_1 GyrI-like small molecule binding domain K15770 - - 0.0007178 45.0
HFD3_k127_313643_0 PFAM Tripartite tricarboxylate transporter TctA family K07793 - - 2.177e-249 777.0
HFD3_k127_313643_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000086 495.0
HFD3_k127_313643_2 Transporter associated domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000516 267.0
HFD3_k127_313643_3 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000000000000000000000000002732 190.0
HFD3_k127_313643_4 Transglycosylase associated protein - - - 0.00000000000000000000001575 102.0
HFD3_k127_3137196_0 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 399.0
HFD3_k127_3145342_0 PFAM V-type ATPase 116 kDa K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009022 557.0
HFD3_k127_3145342_1 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 473.0
HFD3_k127_3145342_3 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000003565 215.0
HFD3_k127_3145342_4 Response regulator, receiver - - - 0.00000000000000000000000000000000003744 140.0
HFD3_k127_3145342_5 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.0000000000000000000004531 98.0
HFD3_k127_3145342_7 Domain of unknown function (DUF4395) - - - 0.00000001183 63.0
HFD3_k127_3169645_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 6.149e-314 967.0
HFD3_k127_3169645_1 DNA topoisomerase VI subunit A K03166 - 5.99.1.3 2.598e-202 633.0
HFD3_k127_3169645_10 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000006522 231.0
HFD3_k127_3169645_11 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000003288 178.0
HFD3_k127_3169645_12 belongs to the thioredoxin family K00384,K03671 - 1.8.1.9 0.000000000000000000000000000000000004699 143.0
HFD3_k127_3169645_13 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000000197 126.0
HFD3_k127_3169645_14 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000000006546 95.0
HFD3_k127_3169645_16 Redoxin - - - 0.000000000000001112 85.0
HFD3_k127_3169645_17 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000003562 82.0
HFD3_k127_3169645_2 Protein of unknown function (DUF1015) - - - 6.394e-196 624.0
HFD3_k127_3169645_3 radical SAM K06871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 616.0
HFD3_k127_3169645_4 Domain of unknown function (DUF3413) K07014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 579.0
HFD3_k127_3169645_5 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 449.0
HFD3_k127_3169645_6 cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 440.0
HFD3_k127_3169645_7 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009192 378.0
HFD3_k127_3169645_8 cell septum assembly - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 302.0
HFD3_k127_3169645_9 TIGRFAM cytochrome C family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005422 304.0
HFD3_k127_3192464_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 7.727e-305 941.0
HFD3_k127_3204855_0 cysteine-type peptidase activity K13695 - - 0.0000000000000000000000000000000000001407 154.0
HFD3_k127_3204855_1 Pfam:DUF2029 - - - 0.00000000000000000000001121 114.0
HFD3_k127_3207189_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1028.0
HFD3_k127_3207189_1 Participates in both transcription termination and antitermination K02600 - - 1.723e-307 959.0
HFD3_k127_3207189_10 exodeoxyribonuclease VII activity K03602 - 3.1.11.6 0.00000000000000000000000001645 111.0
HFD3_k127_3207189_12 Nucleic-acid-binding protein implicated in transcription termination K02600,K07742 - - 0.000000000000000000451 92.0
HFD3_k127_3207189_13 DnaJ molecular chaperone homology domain K03686 - - 0.000000000000000005816 90.0
HFD3_k127_3207189_14 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.000000000229 68.0
HFD3_k127_3207189_15 protein kinase activity K12132 - 2.7.11.1 0.000001592 61.0
HFD3_k127_3207189_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 606.0
HFD3_k127_3207189_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003602 422.0
HFD3_k127_3207189_4 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 355.0
HFD3_k127_3207189_5 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 334.0
HFD3_k127_3207189_6 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006785 298.0
HFD3_k127_3207189_7 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000000000000000000000000000000000000001598 237.0
HFD3_k127_3207189_8 regulator K07773 - - 0.00000000000000000000000000000000000000000000000000000000000001288 233.0
HFD3_k127_3207189_9 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000000000000000006979 133.0
HFD3_k127_3212611_0 Molybdopterin oxidoreductase Fe4S4 domain K02567 - - 0.0 1197.0
HFD3_k127_3212611_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008753 444.0
HFD3_k127_3212611_2 heat shock protein binding - - - 0.000000000000000000000002216 116.0
HFD3_k127_3230562_0 Histidine kinase - - - 1.072e-212 681.0
HFD3_k127_3230562_1 Small GTP-binding protein K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003908 357.0
HFD3_k127_3230562_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 327.0
HFD3_k127_3230562_3 SMART helicase c2 K03722 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000001047 199.0
HFD3_k127_3238124_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 4.247e-210 657.0
HFD3_k127_3238124_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006647 587.0
HFD3_k127_3238124_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 389.0
HFD3_k127_3238124_3 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000000000000000000000000000000000025 200.0
HFD3_k127_3238124_4 synthase K01858 - 5.5.1.4 0.000000000000000000000000000000000000000006132 154.0
HFD3_k127_3238124_5 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000000000000006074 130.0
HFD3_k127_3241454_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.0 1185.0
HFD3_k127_3241454_1 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 426.0
HFD3_k127_3241454_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 362.0
HFD3_k127_3241454_3 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000000000004353 209.0
HFD3_k127_3241454_4 YCII-related domain - - - 0.00000000000000000000000000000000000000000000000000006015 198.0
HFD3_k127_3241454_5 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000002954 119.0
HFD3_k127_3241454_6 UDP-glucose:hexose-1-phosphate uridylyltransferase activity - - - 0.000000000000000000003587 111.0
HFD3_k127_3241454_7 OsmC-like protein K07397 - - 0.0000000000000000521 95.0
HFD3_k127_3241454_8 4 iron, 4 sulfur cluster binding K00176 - 1.2.7.3 0.00000000000006696 77.0
HFD3_k127_3248356_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000007123 206.0
HFD3_k127_3248356_2 OsmC-like protein - - - 0.00000000000000000000000000000000000003617 163.0
HFD3_k127_3248356_3 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000001268 106.0
HFD3_k127_3248965_0 Maltogenic Amylase, C-terminal domain K05341,K05343 - 2.4.1.4,3.2.1.1,5.4.99.16 7.183e-298 919.0
HFD3_k127_3248965_1 ATP-binding region ATPase domain protein - - - 5.031e-209 673.0
HFD3_k127_3248965_2 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 562.0
HFD3_k127_3248965_3 glycosyl transferase family 2 K21349 - 2.4.1.268 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 340.0
HFD3_k127_3248965_4 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001232 250.0
HFD3_k127_3248965_5 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000001322 209.0
HFD3_k127_3248965_6 PFAM Conserved TM helix repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000002101 191.0
HFD3_k127_3251295_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 471.0
HFD3_k127_3251295_1 Mediates influx of magnesium ions K03284,K16074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 381.0
HFD3_k127_3251295_2 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000007432 208.0
HFD3_k127_3253575_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0 1023.0
HFD3_k127_3253575_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 2.673e-248 780.0
HFD3_k127_3253575_2 Cytochrome c - - - 7.023e-206 647.0
HFD3_k127_3253575_3 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 300.0
HFD3_k127_3253575_4 2 iron, 2 sulfur cluster binding K13643 - - 0.00000000000000000001082 98.0
HFD3_k127_3257131_0 Molydopterin dinucleotide binding domain - - - 2.117e-286 913.0
HFD3_k127_3257131_1 RNA polymerase K03088 - - 0.000000000000000000000000000000000000000000000000000001256 204.0
HFD3_k127_3257131_2 LysM domain - - - 0.0000000000000000000000000000000000000000000000000001102 194.0
HFD3_k127_3257131_3 - - - - 0.000000000000000000000000000000002358 132.0
HFD3_k127_3257131_4 YceI-like domain - - - 0.000000000000003387 86.0
HFD3_k127_3260837_0 Surface antigen - - - 7.839e-243 809.0
HFD3_k127_3260837_1 TamB, inner membrane protein subunit of TAM complex K09800 - - 5.811e-221 702.0
HFD3_k127_3260837_2 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006087 528.0
HFD3_k127_3260837_3 Ppx GppA K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 395.0
HFD3_k127_3260837_4 haloacid dehalogenase-like hydrolase K08966 - 3.1.3.87 0.0000000000000000000000000000000000000000000000000000000000000000000000002093 255.0
HFD3_k127_3260837_5 Glutathione-dependent formaldehyde-activating - - - 0.000000000000000000000000000000000000000000000002482 187.0
HFD3_k127_3260837_6 TonB C terminal K03646,K03832 - - 0.000000000000000000000000000000000008897 140.0
HFD3_k127_3296478_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 306.0
HFD3_k127_3296478_1 histidine kinase HAMP region domain protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000008428 240.0
HFD3_k127_3296478_2 Pfam:Cache_2 - - - 0.0000000000000000000000000000353 132.0
HFD3_k127_331003_0 glutaminyl-tRNA K01886 - 6.1.1.18 0.0 1139.0
HFD3_k127_331003_1 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 336.0
HFD3_k127_331003_2 Tellurite resistance protein TerB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007693 325.0
HFD3_k127_331003_3 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002292 269.0
HFD3_k127_331003_4 Enoyl-(Acyl carrier protein) reductase K12677 - - 0.0000000000000000000000000000000000000000000000000000000000000000001252 243.0
HFD3_k127_3313256_0 GMC oxidoreductase K03333 - 1.1.3.6 1.499e-250 782.0
HFD3_k127_3313256_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 500.0
HFD3_k127_3313256_2 PFAM ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 399.0
HFD3_k127_3313256_3 Periplasmic binding protein K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 396.0
HFD3_k127_3313256_4 PFAM AMP-dependent synthetase and ligase K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 381.0
HFD3_k127_3313256_5 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 374.0
HFD3_k127_3313256_6 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 357.0
HFD3_k127_3313256_7 PFAM alpha beta hydrolase fold - - - 0.00000000000000000002236 92.0
HFD3_k127_3313983_0 homoserine dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 411.0
HFD3_k127_3313983_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000005502 224.0
HFD3_k127_3313983_2 - - - - 0.00000000000000000000000000000000000000000000000000007334 200.0
HFD3_k127_3313983_3 endonuclease activity K07451 - - 0.00000006569 55.0
HFD3_k127_3316347_0 Serine Threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005604 575.0
HFD3_k127_3316347_1 positive regulation of macromolecule biosynthetic process K03973 - - 0.00000000000000000000000000000000000000079 150.0
HFD3_k127_3324234_0 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006727 394.0
HFD3_k127_3324234_1 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004004 273.0
HFD3_k127_3324234_2 Lysin motif K06194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000156 278.0
HFD3_k127_3324234_3 Outer membrane protein beta-barrel domain - - - 0.000006552 54.0
HFD3_k127_3329306_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 1.152e-200 629.0
HFD3_k127_3329306_1 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 581.0
HFD3_k127_3331050_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000006805 193.0
HFD3_k127_3332997_0 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000003968 211.0
HFD3_k127_3332997_1 positive regulation of macromolecule biosynthetic process K03973 - - 0.0000000000000000000000000000000000000111 146.0
HFD3_k127_3332997_2 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000006505 111.0
HFD3_k127_3340029_0 PBS lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004262 392.0
HFD3_k127_3340029_1 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000000000000000000005069 175.0
HFD3_k127_3340029_2 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000000001667 157.0
HFD3_k127_335167_0 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 315.0
HFD3_k127_3352136_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 1.513e-199 635.0
HFD3_k127_3352136_1 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 386.0
HFD3_k127_3352136_2 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004684 370.0
HFD3_k127_3352136_3 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 321.0
HFD3_k127_3352136_4 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000003658 263.0
HFD3_k127_3352136_5 PFAM Chorismate mutase of the AroH class K06208 - 5.4.99.5 0.000000000000000000000000000000000000000000000001581 175.0
HFD3_k127_3362077_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 556.0
HFD3_k127_3362077_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006113 347.0
HFD3_k127_3362077_3 metalloendopeptidase activity K03799 - - 0.0000000000001811 72.0
HFD3_k127_3366506_0 DNA helicase K03657 - 3.6.4.12 0.0 1079.0
HFD3_k127_3366506_1 ATP-binding region ATPase domain protein - - - 3.126e-228 722.0
HFD3_k127_3366506_10 response regulator, receiver - - - 0.0000000000000000000000000000000000002622 148.0
HFD3_k127_3366506_11 - - - - 0.0000000000000000000005431 110.0
HFD3_k127_3366506_2 adenosine deaminase K01488 - 3.5.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006036 567.0
HFD3_k127_3366506_3 Voltage-dependent anion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 520.0
HFD3_k127_3366506_4 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 463.0
HFD3_k127_3366506_5 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 388.0
HFD3_k127_3366506_6 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000006898 255.0
HFD3_k127_3366506_7 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006828 251.0
HFD3_k127_3366506_8 PQQ enzyme repeat - - - 0.000000000000000000000000000000000000000000000000000000008067 224.0
HFD3_k127_3366506_9 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000006057 210.0
HFD3_k127_3378962_0 PA domain - - - 0.0 1161.0
HFD3_k127_3378962_1 ATP-dependent helicase HrpB K03579 - 3.6.4.13 0.0000000000000004268 94.0
HFD3_k127_3387036_0 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 351.0
HFD3_k127_3387036_1 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000001611 239.0
HFD3_k127_3387036_2 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000000000000000002432 224.0
HFD3_k127_3387036_3 NAD(P)H-binding K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000004421 196.0
HFD3_k127_3387036_4 Methyltransferase domain K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000484 196.0
HFD3_k127_3387036_5 iron ion binding - - - 0.0000000000000000000000000000000000000000000003397 175.0
HFD3_k127_3387036_6 - - - - 0.0000000000000001567 82.0
HFD3_k127_3418281_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000001971 144.0
HFD3_k127_3418281_2 OmpA family K03286 - - 0.000000000000000000000000000000000008222 155.0
HFD3_k127_3418281_3 Beta-1,3-glucanase - - - 0.0000000000003364 83.0
HFD3_k127_3420697_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 3.665e-281 873.0
HFD3_k127_3420697_1 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 458.0
HFD3_k127_3426570_0 long-chain fatty acid transporting porin activity K06076 - - 0.000000000000000000000000000000000000000000000000000002705 200.0
HFD3_k127_3443378_0 Biopterin-dependent aromatic amino acid hydroxylase K00500 - 1.14.16.1 4.782e-208 662.0
HFD3_k127_3443378_1 Alpha beta hydrolase - - - 0.000000000000000005054 94.0
HFD3_k127_3443378_2 PFAM Hemerythrin HHE cation binding domain protein K07216 - - 0.0000000000000001144 86.0
HFD3_k127_3443378_3 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 0.00000000000002776 77.0
HFD3_k127_3446597_0 Selenocysteine-specific translation elongation factor K03833 - - 1.313e-297 937.0
HFD3_k127_3446597_1 GAF domain - - - 3.715e-278 895.0
HFD3_k127_3446597_2 response regulator K07713 - - 2.248e-215 676.0
HFD3_k127_3446597_3 Phosphoribosyl transferase domain K07101 - - 0.000000000000000000000000000000000000000000000000000000000000000003267 233.0
HFD3_k127_3459399_0 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system - - - 0.000000003855 68.0
HFD3_k127_3462422_0 PFAM phosphoesterase, RecJ domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000898 537.0
HFD3_k127_3462422_1 Aminotransferase, class V K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 507.0
HFD3_k127_3462422_2 PFAM Metallophosphoesterase K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006707 436.0
HFD3_k127_3462422_3 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005398 385.0
HFD3_k127_3462422_4 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 355.0
HFD3_k127_3462422_5 Fic/DOC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 316.0
HFD3_k127_3462422_6 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000000000000000000000000000003945 186.0
HFD3_k127_3462422_7 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.0000000000004387 71.0
HFD3_k127_3462422_8 peptidyl-tyrosine sulfation - - - 0.0000007642 61.0
HFD3_k127_3512768_0 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000799 434.0
HFD3_k127_3512768_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006868 260.0
HFD3_k127_3512768_2 - - - - 0.00000000000000000000000000000000000006601 143.0
HFD3_k127_3512768_3 Arsenical pump membrane protein - - - 0.00000000000000000000000000000001941 127.0
HFD3_k127_3523146_0 TIGRFAM cytochrome C family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005181 422.0
HFD3_k127_3523146_1 TPR repeat - - - 0.000000000000000000000000000000000000001574 155.0
HFD3_k127_3524388_0 Transcriptional regulator K03717 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 427.0
HFD3_k127_3524388_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000000000000000000000001716 225.0
HFD3_k127_3524388_2 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000000000000000000000000000001942 143.0
HFD3_k127_3524388_3 - - - - 0.000000000005767 72.0
HFD3_k127_3524725_0 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 312.0
HFD3_k127_3524725_1 chaperone-mediated protein folding K03654,K14949 - 2.7.11.1,3.6.4.12 0.000000000000000000009116 96.0
HFD3_k127_3549808_0 protein trimerization - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 385.0
HFD3_k127_3562025_0 Methionine synthase K00548 - 2.1.1.13 0.0 1857.0
HFD3_k127_3562025_1 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008223 504.0
HFD3_k127_3562025_2 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000000000000003885 250.0
HFD3_k127_3562025_3 Domain of unknown function (DUF4337) - - - 0.0000000000000000000000000000000000000000000000000002315 192.0
HFD3_k127_3562025_4 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000003633 177.0
HFD3_k127_3564548_0 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 7.522e-293 910.0
HFD3_k127_3564548_1 FAD dependent oxidoreductase K07137 - - 1.242e-242 754.0
HFD3_k127_3564548_2 Mannose-6-phosphate isomerase - - - 0.0000000000000000000000000000000000000000000000000000001098 198.0
HFD3_k127_3564548_3 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.00000000000000000000000000000000000000000000738 168.0
HFD3_k127_3564548_4 Sporulation related domain - - - 0.0000000000000000000000000000000000000002637 158.0
HFD3_k127_3571557_0 Histidine kinase K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 435.0
HFD3_k127_3571557_1 iron ion homeostasis - - - 0.0000000000000000000000000000000000000000000000001065 189.0
HFD3_k127_3571557_2 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000005421 175.0
HFD3_k127_3575436_0 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 422.0
HFD3_k127_3575436_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000129 253.0
HFD3_k127_3577391_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000004983 215.0
HFD3_k127_3577391_2 Transmembrane anti-sigma factor - - - 0.00000000000000002226 93.0
HFD3_k127_3583090_0 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000848 419.0
HFD3_k127_3583090_1 Methyl-transferase K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000002895 240.0
HFD3_k127_3583090_2 Methyl-transferase K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000009589 188.0
HFD3_k127_3593595_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 2.545e-212 681.0
HFD3_k127_3597331_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 7.163e-210 661.0
HFD3_k127_3597331_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 480.0
HFD3_k127_3597331_2 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 363.0
HFD3_k127_3597331_3 Domain of unknown function (DUF2437) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 374.0
HFD3_k127_3597331_4 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000008676 218.0
HFD3_k127_3597331_5 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000008281 149.0
HFD3_k127_3599124_0 Type II and III secretion system protein K02453 - - 2.763e-282 885.0
HFD3_k127_3600014_0 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000519 555.0
HFD3_k127_3600014_1 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006357 511.0
HFD3_k127_36006_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1197.0
HFD3_k127_36006_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 448.0
HFD3_k127_36006_2 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 443.0
HFD3_k127_36006_3 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008118 301.0
HFD3_k127_36006_4 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009174 278.0
HFD3_k127_36006_5 Acetoacetate decarboxylase (ADC) - - - 0.000000000000000000000000000000000000000000000008964 192.0
HFD3_k127_36006_6 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000003412 153.0
HFD3_k127_3610183_0 Peptidase dimerisation domain - - - 2.838e-216 679.0
HFD3_k127_3610183_1 two component, sigma54 specific, transcriptional regulator, Fis family K07713 - - 3.109e-205 671.0
HFD3_k127_3610183_2 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 538.0
HFD3_k127_3610183_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005406 478.0
HFD3_k127_3610183_4 PFAM ATP-binding region, ATPase domain protein K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 448.0
HFD3_k127_3610183_5 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005794 385.0
HFD3_k127_3610183_6 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 350.0
HFD3_k127_3610183_7 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 340.0
HFD3_k127_3610183_8 - - - - 0.000000000000000000000000000000000000000001607 177.0
HFD3_k127_3614125_0 Carboxyl transferase domain K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 5.702e-274 850.0
HFD3_k127_3614125_1 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 559.0
HFD3_k127_3614125_2 RDD family - - - 0.000000000000000000000000000000003167 137.0
HFD3_k127_3624137_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 4.8e-285 884.0
HFD3_k127_3624137_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 569.0
HFD3_k127_3624137_10 transferase activity, transferring glycosyl groups K12994 - 2.4.1.349 0.00000000000000000000000000000000000000000001027 177.0
HFD3_k127_3624137_11 - - - - 0.000000000000000000000003468 112.0
HFD3_k127_3624137_2 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008624 567.0
HFD3_k127_3624137_3 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 432.0
HFD3_k127_3624137_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 400.0
HFD3_k127_3624137_5 RmlD substrate binding domain K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 312.0
HFD3_k127_3624137_6 chemotaxis K03408 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003004 246.0
HFD3_k127_3624137_7 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.000000000000000000000000000000000000000000000000000000000000001418 242.0
HFD3_k127_3624137_8 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000001206 209.0
HFD3_k127_3624137_9 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000000000000000000000000001465 194.0
HFD3_k127_3624500_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 4.396e-288 904.0
HFD3_k127_3624500_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 1.414e-218 688.0
HFD3_k127_3624500_2 COG1073 hydrolases of the alpha beta superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005727 446.0
HFD3_k127_3624500_3 long-chain fatty acid transporting porin activity K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000099 313.0
HFD3_k127_3624500_5 PFAM amino acid-binding ACT domain protein - - - 0.000000000002945 68.0
HFD3_k127_3624500_6 Cysteine rich repeat - - - 0.000000001795 67.0
HFD3_k127_3624804_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009172 452.0
HFD3_k127_3624804_1 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004966 315.0
HFD3_k127_3624804_2 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003788 259.0
HFD3_k127_3624804_3 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000001458 212.0
HFD3_k127_3624804_4 ABC transporter K02013 - 3.6.3.34 0.00000000000000000000002742 114.0
HFD3_k127_3626201_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1258.0
HFD3_k127_3626201_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 5.825e-321 1012.0
HFD3_k127_3626201_10 SMART helix-turn-helix domain protein K15539 - - 0.0000000000000001181 94.0
HFD3_k127_3626201_2 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 576.0
HFD3_k127_3626201_3 TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 308.0
HFD3_k127_3626201_4 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 298.0
HFD3_k127_3626201_6 - - - - 0.0000000000000000000000000000000000000000000000000000000001831 206.0
HFD3_k127_3626201_9 YdjC-like protein - - - 0.0000000000000000000000000001133 121.0
HFD3_k127_3627459_0 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 368.0
HFD3_k127_3627459_1 ABC transporter K01996,K11963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 363.0
HFD3_k127_3627459_2 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 304.0
HFD3_k127_3627459_3 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.00000000000000000000000000000000000001285 144.0
HFD3_k127_3639457_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006618 272.0
HFD3_k127_3660947_0 Pfam:CPSase_L_chain - - - 0.0 1461.0
HFD3_k127_3660947_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.247e-261 824.0
HFD3_k127_3660947_2 CoA-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 566.0
HFD3_k127_3660947_3 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 404.0
HFD3_k127_3660947_4 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006966 368.0
HFD3_k127_3660947_5 NMT1-like family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 370.0
HFD3_k127_3660947_7 Protein of unknown function (DUF1697) - - - 0.000000000000000000001097 110.0
HFD3_k127_3667904_0 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.0000000000000000000000000000000000000000000000000000000000000005107 233.0
HFD3_k127_3667904_1 TetR Family - - - 0.00000000000000000000000000000214 128.0
HFD3_k127_3681482_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 4.688e-271 869.0
HFD3_k127_3681482_1 fatty acid hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000003598 221.0
HFD3_k127_3691076_0 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 435.0
HFD3_k127_3691076_1 Coproporphyrinogen III oxidase K00228 - 1.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 415.0
HFD3_k127_372689_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000001903 231.0
HFD3_k127_372689_1 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000001821 196.0
HFD3_k127_372689_2 Protein of unknown function (DUF421) - - - 0.00000000000000000000000000000002866 142.0
HFD3_k127_372689_3 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.0000000000004818 70.0
HFD3_k127_3727917_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 602.0
HFD3_k127_3727917_1 SMART Tetratricopeptide domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 580.0
HFD3_k127_3727917_10 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000003087 254.0
HFD3_k127_3727917_11 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000003988 240.0
HFD3_k127_3727917_13 PFAM thioesterase superfamily protein - - - 0.00000000000000000000009504 108.0
HFD3_k127_3727917_14 Phosphopantetheine attachment site - - - 0.00000000000000002907 92.0
HFD3_k127_3727917_2 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006886 535.0
HFD3_k127_3727917_3 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004799 532.0
HFD3_k127_3727917_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007105 381.0
HFD3_k127_3727917_5 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 391.0
HFD3_k127_3727917_6 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 398.0
HFD3_k127_3727917_7 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 322.0
HFD3_k127_3727917_8 Pregnancy-associated plasma protein-A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 323.0
HFD3_k127_3727917_9 acetyltransferase component of pyruvate dehydrogenase complex K00627,K00658 - 2.3.1.12,2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001648 275.0
HFD3_k127_3730234_1 PGAP1-like protein K01046 - 3.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000005511 233.0
HFD3_k127_3730234_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000004941 173.0
HFD3_k127_373188_0 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003928 620.0
HFD3_k127_373188_2 - - - - 0.0000000000000000000000001225 113.0
HFD3_k127_3765743_0 signal peptide peptidase SppA, 36K type K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 553.0
HFD3_k127_3770596_0 Protein of unknown function (DUF1343) - - - 1.025e-199 630.0
HFD3_k127_3770596_1 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000738 304.0
HFD3_k127_3770596_2 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000002458 187.0
HFD3_k127_3775790_0 D-isomer specific 2-hydroxyacid dehydrogenase K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 7.073e-243 760.0
HFD3_k127_3775790_1 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008598 347.0
HFD3_k127_3775790_2 - - - - 0.000703 42.0
HFD3_k127_3780531_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 1.876e-304 955.0
HFD3_k127_3780531_1 Pfam Transposase IS66 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 462.0
HFD3_k127_3780531_2 PFAM iron dependent repressor K03709 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004433 315.0
HFD3_k127_3780531_3 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC K06148,K16012 - - 0.0000000000000000000000000000000000000000000000000000000000000006601 231.0
HFD3_k127_3780531_4 FMN binding - - - 0.00000000000000000000000000000000000000000000000000002439 213.0
HFD3_k127_3780531_5 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000379 188.0
HFD3_k127_3780531_8 Regulatory protein, FmdB family - - - 0.0000000000000000000001306 111.0
HFD3_k127_3789966_0 TrkA-C domain K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 615.0
HFD3_k127_3789966_1 ErfK YbiS YcfS YnhG family protein K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004961 293.0
HFD3_k127_3789966_2 Bacterial protein of unknown function (DUF882) - - - 0.0000000000000000000000000000000000000004636 155.0
HFD3_k127_3802829_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 5.21e-262 811.0
HFD3_k127_3802829_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 300.0
HFD3_k127_3802829_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009993 257.0
HFD3_k127_3802829_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.00000000000000000000000000000000000000000000001598 173.0
HFD3_k127_3803755_0 long-chain fatty acid transport protein - - - 0.00000000000000000000000000000001306 132.0
HFD3_k127_3813660_0 Acetyl-CoA hydrolase/transferase N-terminal domain - - - 2.842e-205 644.0
HFD3_k127_3813660_1 Histidine kinase K15011 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 398.0
HFD3_k127_3813660_2 CoA-substrate-specific enzyme activase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009341 316.0
HFD3_k127_3813660_3 Bacterial extracellular solute-binding protein K10938 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005391 259.0
HFD3_k127_3813660_4 response regulator K15012 - - 0.00000000000000000000000000000000000000000000000000000000000000022 232.0
HFD3_k127_3833325_0 Prolyl oligopeptidase family - - - 2.611e-270 860.0
HFD3_k127_3833325_1 TGS domain K06944 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 459.0
HFD3_k127_3833325_2 SAF K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 351.0
HFD3_k127_3833325_3 Late embryogenesis abundant protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002014 259.0
HFD3_k127_3833325_4 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000001067 238.0
HFD3_k127_3836257_0 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 586.0
HFD3_k127_3836257_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 589.0
HFD3_k127_3836257_2 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 496.0
HFD3_k127_3864813_0 Peptidase dimerisation domain - - - 9.167e-202 642.0
HFD3_k127_3864813_1 lysine 2,3-aminomutase K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 522.0
HFD3_k127_3864813_10 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000003926 126.0
HFD3_k127_3864813_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 459.0
HFD3_k127_3864813_3 endonuclease activity K07451 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009823 392.0
HFD3_k127_3864813_4 lysine 2,3-aminomutase K01843 - 5.4.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 359.0
HFD3_k127_3864813_5 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 331.0
HFD3_k127_3864813_6 cellulase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008455 318.0
HFD3_k127_3864813_7 Stage II sporulation D domain protein K06381 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008646 299.0
HFD3_k127_3864813_9 lysine 2,3-aminomutase K01843 - 5.4.3.2 0.0000000000000000000000000000000000000000000000000000000004705 205.0
HFD3_k127_3879422_0 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004042 493.0
HFD3_k127_3879422_1 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 408.0
HFD3_k127_3879422_2 Protein of unknown function (DUF1460) - - - 0.000000000000000000000000000000000000000000000000004249 195.0
HFD3_k127_3879422_3 cheY-homologous receiver domain K07657 - - 0.0000000000000000000000000000000003524 135.0
HFD3_k127_3879422_4 Domain of unknown function (DUF4388) - - - 0.0000000000000000000002634 99.0
HFD3_k127_3883181_0 Required for morphogenesis under gluconeogenic growth conditions - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 364.0
HFD3_k127_3883181_1 Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000001669 259.0
HFD3_k127_3883683_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 5.55e-226 722.0
HFD3_k127_3883683_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 383.0
HFD3_k127_3883683_2 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 370.0
HFD3_k127_3883683_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006982 339.0
HFD3_k127_3883683_4 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001032 267.0
HFD3_k127_3883683_5 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000002802 214.0
HFD3_k127_3883683_6 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000002404 213.0
HFD3_k127_3883683_7 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) K02907 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000002445 124.0
HFD3_k127_3883683_8 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000007523 87.0
HFD3_k127_3883683_9 Belongs to the bacterial ribosomal protein bL36 family K02919 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000995 78.0
HFD3_k127_3893358_0 aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 1.512e-201 637.0
HFD3_k127_3893358_1 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 477.0
HFD3_k127_3893358_2 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007849 402.0
HFD3_k127_3902267_0 CoA-transferase family III K01796 - 5.1.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 576.0
HFD3_k127_3902267_1 Belongs to the bacterial solute-binding protein 9 family K02077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 398.0
HFD3_k127_3902267_10 Restriction endonuclease K07448 - - 0.000009605 52.0
HFD3_k127_3902267_2 Tfp pilus assembly protein FimV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007589 369.0
HFD3_k127_3902267_3 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 346.0
HFD3_k127_3902267_4 ABC 3 transport family K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 347.0
HFD3_k127_3902267_5 PFAM ABC transporter K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000571 329.0
HFD3_k127_3902267_6 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000238 171.0
HFD3_k127_3902267_8 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.000000000000000000000000000335 122.0
HFD3_k127_3902267_9 SCP-2 sterol transfer family - - - 0.00000000000000000002383 90.0
HFD3_k127_3908154_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009433 586.0
HFD3_k127_3908154_1 TIGRFAM amidohydrolase K12941 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 364.0
HFD3_k127_3908154_2 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000000001027 118.0
HFD3_k127_3918688_0 cytochrome C peroxidase - - - 4.803e-203 641.0
HFD3_k127_3918688_1 PDZ DHR GLGF domain protein K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 523.0
HFD3_k127_3918688_10 domain, Protein - - - 0.000000000000000000000000000003703 137.0
HFD3_k127_3918688_2 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004726 411.0
HFD3_k127_3918688_3 Sir2 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006316 414.0
HFD3_k127_3918688_4 Peptidase C26 K07010 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005196 319.0
HFD3_k127_3918688_5 PFAM Phosphomethylpyrimidine kinase K00941,K14153,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000002203 278.0
HFD3_k127_3918688_6 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000003719 229.0
HFD3_k127_3918688_7 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000001064 242.0
HFD3_k127_3918688_8 Methyl-transferase K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000478 180.0
HFD3_k127_3918688_9 Domain of unknown function (DUF1844) - - - 0.0000000000000000000000000000001183 131.0
HFD3_k127_3921740_0 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000054 411.0
HFD3_k127_3921740_1 Belongs to the GST superfamily K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000009137 268.0
HFD3_k127_3921740_2 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000007926 222.0
HFD3_k127_3921740_3 Belongs to the ompA family K03640 - - 0.0000009269 61.0
HFD3_k127_3923775_0 Pirin K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 346.0
HFD3_k127_3923775_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009497 346.0
HFD3_k127_3923775_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009655 331.0
HFD3_k127_3923775_3 GMP synthase (glutamine-hydrolyzing) activity K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000001164 178.0
HFD3_k127_3923775_4 - - - - 0.00000000000000000000006325 110.0
HFD3_k127_3923775_5 Prolyl oligopeptidase family - - - 0.000000000211 61.0
HFD3_k127_3926072_0 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004318 612.0
HFD3_k127_3926072_1 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000436 278.0
HFD3_k127_3926072_2 - - - - 0.0000000000000000000000000000000000000000000000000000001498 214.0
HFD3_k127_3926072_4 Tetratricopeptide repeat - - - 0.00000000004981 67.0
HFD3_k127_3960653_0 Serine Threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 335.0
HFD3_k127_3960653_1 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000005841 234.0
HFD3_k127_3960653_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000002394 141.0
HFD3_k127_3982988_0 Major facilitator K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004185 533.0
HFD3_k127_3982988_1 Acetoacetate decarboxylase (ADC) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000921 373.0
HFD3_k127_3982988_10 cellulase activity - - - 0.00000000004165 76.0
HFD3_k127_3982988_2 TIGRFAM RHS repeat-associated core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009524 306.0
HFD3_k127_3982988_3 Protein of unknown function (DUF1211) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000445 263.0
HFD3_k127_3982988_4 Protein of unknown function, DUF393 - - - 0.0000000000000000000000000000000002049 141.0
HFD3_k127_3982988_5 Cupin domain - - - 0.000000000000000000000000000002072 126.0
HFD3_k127_3982988_6 PA domain - - - 0.00000000000000000000000000008998 135.0
HFD3_k127_3982988_7 Protein of unknown function (DUF2721) - - - 0.0000000000000000000000001063 124.0
HFD3_k127_3989300_0 Tetratricopeptide repeat - - - 3.501e-257 859.0
HFD3_k127_3989300_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 346.0
HFD3_k127_3992223_0 copper-translocating P-type ATPase K17686 - 3.6.3.54 8.387e-229 718.0
HFD3_k127_3992223_1 fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 2.764e-202 635.0
HFD3_k127_3992223_2 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000003817 245.0
HFD3_k127_3992223_3 fumarate reductase) cytochrome b subunit K00241 - - 0.000000000000000000000000000000000000000000000000000000000000003883 226.0
HFD3_k127_4002983_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 2.373e-222 700.0
HFD3_k127_4002983_1 TIGRFAM galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000255 256.0
HFD3_k127_4042896_0 PFAM Polysulphide reductase, NrfD - - - 9.724e-209 669.0
HFD3_k127_4042896_1 Polysulphide reductase, NrfD K00185 - - 4.826e-201 636.0
HFD3_k127_4042896_10 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.000000000000000000000000000000000000000000000000000000006766 211.0
HFD3_k127_4042896_11 Cytochrome c K00406,K08906 - - 0.00000000000000000001028 107.0
HFD3_k127_4042896_2 cytochrome c biogenesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000572 540.0
HFD3_k127_4042896_3 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 492.0
HFD3_k127_4042896_4 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 476.0
HFD3_k127_4042896_5 response regulator K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 475.0
HFD3_k127_4042896_6 PFAM Cytochrome c assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 444.0
HFD3_k127_4042896_7 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007378 407.0
HFD3_k127_4042896_8 Appr-1'-p processing enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007877 250.0
HFD3_k127_4042896_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000005997 237.0
HFD3_k127_4059580_0 pilus assembly protein K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000786 552.0
HFD3_k127_4059580_1 Type II secretion system (T2SS), protein M subtype b K02664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001029 267.0
HFD3_k127_4059580_2 Fimbrial assembly protein (PilN) K02663 - - 0.00000000000000000000000000000000000000000000000000008123 207.0
HFD3_k127_4059580_3 Helix-turn-helix XRE-family like proteins - - - 0.000007517 48.0
HFD3_k127_4081711_0 major pilin protein fima - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 410.0
HFD3_k127_4081711_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 326.0
HFD3_k127_4118581_0 Signal transduction histidine kinase - - - 0.0 1018.0
HFD3_k127_4118581_1 Transglycosylase SLT domain K08309 - - 7.869e-206 667.0
HFD3_k127_4118581_2 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005564 356.0
HFD3_k127_412701_0 Oligoendopeptidase f - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 531.0
HFD3_k127_412701_1 PFAM NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 475.0
HFD3_k127_4132367_0 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 447.0
HFD3_k127_4132367_1 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005371 361.0
HFD3_k127_4132367_2 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004354 283.0
HFD3_k127_4132367_3 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000000000000000000000002433 238.0
HFD3_k127_4132367_4 PFAM glycosyl transferase family 9 K02843 - - 0.00000000000000000000000000000000000000000113 169.0
HFD3_k127_4132367_5 - - - - 0.0000000000000000007644 92.0
HFD3_k127_4132367_6 Belongs to the UPF0434 family K09791 - - 0.0000000000000000009833 93.0
HFD3_k127_4150631_0 PFAM Integrase catalytic region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 455.0
HFD3_k127_4161194_0 Biotin carboxylase K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 1.63e-233 730.0
HFD3_k127_4161194_1 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004695 556.0
HFD3_k127_4161194_2 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005935 354.0
HFD3_k127_4161194_3 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000000000001893 179.0
HFD3_k127_4161194_4 Roadblock/LC7 domain - - - 0.00000000000000000000000000000000000000000000002412 173.0
HFD3_k127_418798_0 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008154 551.0
HFD3_k127_418798_1 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007894 556.0
HFD3_k127_418798_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008599 533.0
HFD3_k127_418798_3 transcriptional regulator K09017,K18301 - - 0.00000000000000000000000000000000000000000000000000000000000000000001679 239.0
HFD3_k127_418798_4 deoxyribonuclease V activity K05982 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0034641,GO:0043170,GO:0043737,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.7 0.000000000000000000000000000000000000000000000001165 196.0
HFD3_k127_418798_5 - - - - 0.00000000000000000000000298 108.0
HFD3_k127_4192320_0 HB1, ASXL, restriction endonuclease HTH domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 561.0
HFD3_k127_4192320_1 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000391 234.0
HFD3_k127_4205754_0 Beta-Casp domain K07576 - - 4.142e-205 647.0
HFD3_k127_4205754_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 567.0
HFD3_k127_4205754_2 - K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004271 510.0
HFD3_k127_4205754_3 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009648 394.0
HFD3_k127_4205754_4 Nudix hydrolase K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000004956 234.0
HFD3_k127_4205754_6 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000000000000000000002114 200.0
HFD3_k127_4205754_7 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000004539 193.0
HFD3_k127_4205754_9 translation initiation factor activity K06996 - - 0.000000000000000000000000002248 116.0
HFD3_k127_4205981_0 Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005881 265.0
HFD3_k127_4205981_2 Glutathione S-transferase K00799 GO:0000302,GO:0003674,GO:0003824,GO:0004364,GO:0006950,GO:0006979,GO:0008150,GO:0009636,GO:0010035,GO:0016740,GO:0016765,GO:0042221,GO:0042493,GO:0042542,GO:0046677,GO:0050896,GO:1901700 2.5.1.18 0.00000000000000000000007774 99.0
HFD3_k127_4205981_3 Glycosyltransferase family 28 N-terminal domain - - - 0.00000000000000000007464 92.0
HFD3_k127_4213183_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 1.188e-236 750.0
HFD3_k127_4213183_1 RDD family - - - 0.00000000000000000000000000000000000000000000000000000000000000006972 226.0
HFD3_k127_4213183_2 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000009841 106.0
HFD3_k127_4221042_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 6.577e-297 924.0
HFD3_k127_4221042_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 3.825e-257 801.0
HFD3_k127_4221042_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 610.0
HFD3_k127_4221042_3 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 515.0
HFD3_k127_4221042_4 phosphorelay signal transduction system - - - 0.0000000000000000000001795 102.0
HFD3_k127_4233104_0 radical SAM domain protein - - - 1.099e-197 624.0
HFD3_k127_4233104_1 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 4.917e-197 651.0
HFD3_k127_4233104_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000043 648.0
HFD3_k127_4233104_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 361.0
HFD3_k127_4233104_4 Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009301 332.0
HFD3_k127_4233104_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 305.0
HFD3_k127_4233104_6 AntiSigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003698 267.0
HFD3_k127_4233104_7 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000003814 184.0
HFD3_k127_4233104_8 - K07018 - - 0.00000000000000005728 85.0
HFD3_k127_4253153_0 PFAM 4Fe-4S - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 297.0
HFD3_k127_4253153_1 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.0000000000000000000000000000000000000000000000000000000003262 207.0
HFD3_k127_4253153_2 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000005089 106.0
HFD3_k127_425412_0 Molybdopterin oxidoreductase K00370,K17050 - 1.7.5.1 2.183e-232 734.0
HFD3_k127_425412_1 - K07112 - - 0.0000000000000000000000000000000000000000000000000000000002545 212.0
HFD3_k127_425412_2 thiosulfate sulfurtransferase activity K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000001866 122.0
HFD3_k127_4257954_0 UvrD/REP helicase N-terminal domain - - - 0.0 1078.0
HFD3_k127_4257954_1 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006278 492.0
HFD3_k127_4257954_2 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006546 461.0
HFD3_k127_4257954_3 PFAM ABC transporter K05847 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 304.0
HFD3_k127_4257954_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000004355 67.0
HFD3_k127_4261535_0 Receptor family ligand binding region K01999 - - 8.924e-204 642.0
HFD3_k127_4261535_1 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 284.0
HFD3_k127_4267048_0 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0 1182.0
HFD3_k127_4267048_1 PFAM Molybdopterin oxidoreductase Fe4S4 region K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 293.0
HFD3_k127_4267048_2 Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 299.0
HFD3_k127_4267048_3 Necessary for formate dehydrogenase activity K02380 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001715 276.0
HFD3_k127_4267048_4 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000408 258.0
HFD3_k127_4267048_5 Protein of unknown function (DUF1697) - - - 0.000002515 51.0
HFD3_k127_4279795_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 6.624e-301 945.0
HFD3_k127_4279795_1 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000001544 242.0
HFD3_k127_429635_0 ATPase family associated with various cellular activities (AAA) K06027 - 3.6.4.6 4.389e-221 694.0
HFD3_k127_429635_1 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007708 320.0
HFD3_k127_429635_2 Helix-hairpin-helix class 2 (Pol1 family) motifs - - - 0.00000000000000000000000000000000000000000000000005239 181.0
HFD3_k127_429635_3 - - - - 0.000000000006676 79.0
HFD3_k127_429635_4 Alternative locus ID - - - 0.000001858 54.0
HFD3_k127_4298919_0 AAA ATPase domain - - - 2.153e-254 820.0
HFD3_k127_4298919_1 3-oxo-5-alpha-steroid 4-dehydrogenase K12343 - 1.3.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 317.0
HFD3_k127_4298919_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000476 295.0
HFD3_k127_4298919_3 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000666 302.0
HFD3_k127_4302926_0 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 353.0
HFD3_k127_4302926_1 endonuclease activity K07451 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009484 257.0
HFD3_k127_4302926_2 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000005831 143.0
HFD3_k127_4302926_3 Cold shock protein K03704 - - 0.00000000000000000000000000000000001436 138.0
HFD3_k127_4302926_4 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000000000000006208 129.0
HFD3_k127_4302926_5 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.000000000000000000000000004467 113.0
HFD3_k127_431571_0 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 517.0
HFD3_k127_431571_1 MatE K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 360.0
HFD3_k127_431571_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000001687 234.0
HFD3_k127_4321922_0 repeat protein - - - 0.0 2156.0
HFD3_k127_4321922_1 RDD family K18481 - - 0.000000000000000000000433 98.0
HFD3_k127_4335735_0 protein related to plant photosystem II stability assembly factor - - - 1.842e-197 620.0
HFD3_k127_4335735_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 299.0
HFD3_k127_4335735_2 ThiS family K03636 - - 0.00000000000000000000000000009953 131.0
HFD3_k127_4335735_3 Transcriptional regulator - - - 0.00000000000000000012 89.0
HFD3_k127_434139_0 pyruvate phosphate dikinase K01006 - 2.7.9.1 0.0 1421.0
HFD3_k127_434139_1 Protein-disulfide isomerase - - - 3.399e-245 776.0
HFD3_k127_434139_10 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 308.0
HFD3_k127_434139_11 TRAP transporter T-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003486 258.0
HFD3_k127_434139_12 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000001065 236.0
HFD3_k127_434139_13 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000001479 226.0
HFD3_k127_434139_14 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000001507 245.0
HFD3_k127_434139_15 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000000000000000000000000008474 240.0
HFD3_k127_434139_16 ApaG domain K06195 - - 0.00000000000000000000000000000000000000000000000002335 186.0
HFD3_k127_434139_17 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000002659 208.0
HFD3_k127_434139_18 Biopolymer transport protein K03559 - - 0.00000000000000000000000000000000000000000000227 170.0
HFD3_k127_434139_19 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000000000000000003394 126.0
HFD3_k127_434139_2 Thiamine biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 571.0
HFD3_k127_434139_3 Ferredoxin-fold anticodon binding domain K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 480.0
HFD3_k127_434139_4 Cell division protein FtsI penicillin-binding protein 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000682 467.0
HFD3_k127_434139_5 PFAM Silent information regulator protein Sir2 K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 429.0
HFD3_k127_434139_6 Heat shock protein DnaJ domain protein K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 436.0
HFD3_k127_434139_7 Dihydrodipicolinate reductase, N-terminus K21672 - 1.4.1.12,1.4.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 396.0
HFD3_k127_434139_8 Dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 320.0
HFD3_k127_434139_9 PFAM MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 312.0
HFD3_k127_4354627_0 zinc-ribbon domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 631.0
HFD3_k127_4354627_1 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 507.0
HFD3_k127_4354627_2 Acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005051 456.0
HFD3_k127_4354627_3 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006784 440.0
HFD3_k127_4354627_4 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008696 381.0
HFD3_k127_4354627_5 Outer membrane efflux protein K12543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 386.0
HFD3_k127_4354627_6 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007815 377.0
HFD3_k127_4354627_7 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000488 284.0
HFD3_k127_4377607_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0 1234.0
HFD3_k127_4377607_1 FtsX-like permease family - - - 3.347e-264 832.0
HFD3_k127_4377607_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000905 545.0
HFD3_k127_4377607_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 405.0
HFD3_k127_4377607_4 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008621 349.0
HFD3_k127_4377607_5 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006592 355.0
HFD3_k127_4377607_6 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000000000000001082 190.0
HFD3_k127_4377607_7 Cysteine-rich CPXCG - - - 0.000000000000000000000000001677 111.0
HFD3_k127_4381268_0 protein conserved in bacteria K07793 - - 8.265e-211 669.0
HFD3_k127_4381268_1 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007442 567.0
HFD3_k127_4381268_10 Major Facilitator Superfamily K08177 - - 0.000000000000000000001126 103.0
HFD3_k127_4381268_11 DNA helicase K03654 - 3.6.4.12 0.00000000000000176 80.0
HFD3_k127_4381268_12 Protein of unknown function (DUF2845) - - - 0.0000315 50.0
HFD3_k127_4381268_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 532.0
HFD3_k127_4381268_3 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170,K19071 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 474.0
HFD3_k127_4381268_4 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 389.0
HFD3_k127_4381268_5 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00171,K00172,K19072 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 346.0
HFD3_k127_4381268_6 thiolester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 302.0
HFD3_k127_4381268_7 FCD K05799 - - 0.0000000000000000000000000000000000000000000005521 176.0
HFD3_k127_4381268_8 phospho-2-dehydro-3-deoxyheptonate aldolase K03856,K04516 - 2.5.1.54,5.4.99.5 0.00000000000000000000000000000000000005838 143.0
HFD3_k127_4381268_9 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000000002037 138.0
HFD3_k127_4404933_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 565.0
HFD3_k127_4404933_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.0000000000000000000000000000925 133.0
HFD3_k127_4417783_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1021.0
HFD3_k127_4417783_1 COG2513 PEP phosphonomutase and related enzymes K03417 - 4.1.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 327.0
HFD3_k127_4417783_2 - - - - 0.00000000000000000000000000000000000000000000000000004004 199.0
HFD3_k127_4417783_3 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine K04068 - 1.97.1.4 0.00000000000000000000000000000000000000000000000001342 191.0
HFD3_k127_4417783_4 response regulator K03654 - 3.6.4.12 0.0000000000000000000003186 96.0
HFD3_k127_4417783_5 Helix-hairpin-helix class 2 (Pol1 family) motifs - - - 0.0000000000000002541 91.0
HFD3_k127_4418049_0 PFAM oxidoreductase FAD NAD(P)-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 316.0
HFD3_k127_4418049_1 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001102 287.0
HFD3_k127_4418049_2 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000001793 207.0
HFD3_k127_4418049_3 - - - - 0.0000000000000004283 85.0
HFD3_k127_441909_0 PFAM H transporting two-sector ATPase alpha beta subunit central region K02412,K03224 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 613.0
HFD3_k127_441909_1 transglycosylase K08309 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009274,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 540.0
HFD3_k127_441909_2 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 383.0
HFD3_k127_441909_3 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004879 352.0
HFD3_k127_441909_4 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 318.0
HFD3_k127_441909_6 flagellar assembly protein FliH K02411 - - 0.000002733 55.0
HFD3_k127_4424261_0 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003957 343.0
HFD3_k127_4424261_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000009612 154.0
HFD3_k127_4430910_0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit K01844 - 5.4.3.3 2.3e-278 863.0
HFD3_k127_4430910_1 Pfam:Kce K18013 - 2.3.1.247 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 447.0
HFD3_k127_4430910_2 Dimerisation domain of d-ornithine 4,5-aminomutase K18011 - 5.4.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009951 406.0
HFD3_k127_4430910_3 Thioesterase superfamily K18014 - 4.3.1.14 0.0000000000000000000000000000000000000000000000000000000000008534 216.0
HFD3_k127_4430910_6 Belongs to the bacterial histone-like protein family K03530 - - 0.000000000000000000000000000000000001753 139.0
HFD3_k127_4438707_0 GTP-binding protein K06207 - - 8.576e-247 766.0
HFD3_k127_4438707_1 Histidine kinase HAMP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 616.0
HFD3_k127_4438707_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 400.0
HFD3_k127_4438707_3 Domains REC, sigma54 interaction, HTH8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 427.0
HFD3_k127_4438707_4 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 389.0
HFD3_k127_4438707_5 TIGRFAM cytochrome C family protein - - - 0.0000000000000000000000000000000000000000000001894 178.0
HFD3_k127_4438707_6 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000003788 172.0
HFD3_k127_4448774_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 552.0
HFD3_k127_4448774_1 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 479.0
HFD3_k127_4454042_0 Spondin_N - - - 0.000000000000000000000000000000000000000773 160.0
HFD3_k127_4454042_1 Dienelactone hydrolase family - - - 0.0000000000000000000000000004646 115.0
HFD3_k127_4454220_0 AAA ATPase domain - - - 5.196e-307 975.0
HFD3_k127_4454220_1 OPT oligopeptide transporter protein - - - 0.0000000002685 64.0
HFD3_k127_4455043_0 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 466.0
HFD3_k127_4455043_1 Acetamidase/Formamidase family K01455 - 3.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 430.0
HFD3_k127_4458071_2 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.000000000000000000000000000000000000000000000000000000000001103 214.0
HFD3_k127_4458071_4 Copper chaperone PCu(A)C K09796 - - 0.0000000000006696 76.0
HFD3_k127_4461395_0 Natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 342.0
HFD3_k127_4461395_1 MgtE intracellular - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001659 266.0
HFD3_k127_4465388_0 Histidine kinase - - - 1.141e-200 637.0
HFD3_k127_4465388_1 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 632.0
HFD3_k127_4465388_2 PFAM Hemerythrin HHE cation binding domain K07216 - - 0.000000000000000000000000003927 115.0
HFD3_k127_4466117_0 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009444 355.0
HFD3_k127_4466117_1 Iron-sulfur cluster assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000003424 212.0
HFD3_k127_4466117_2 histone H2A K63-linked ubiquitination K02283 - - 0.0000000000000000000000000000000000241 152.0
HFD3_k127_4466117_3 SUF system FeS assembly protein K04488 - - 0.0000000000000000000000000002684 116.0
HFD3_k127_4470085_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1490.0
HFD3_k127_4470085_1 4Fe-4S dicluster domain - - - 9.8e-322 1016.0
HFD3_k127_4470085_10 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000003219 67.0
HFD3_k127_4470085_2 Belongs to the RimK family K05844,K14940 - 6.3.2.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008328 460.0
HFD3_k127_4470085_4 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004151 309.0
HFD3_k127_4470085_5 Peptidase family M54 K06974 - - 0.0000000000000000000000000000000000000000000000000000004794 198.0
HFD3_k127_4470085_6 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000004134 175.0
HFD3_k127_4470085_8 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000001312 111.0
HFD3_k127_4487060_0 Peptidase family M49 - - - 3.448e-216 686.0
HFD3_k127_4492382_0 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008084 511.0
HFD3_k127_4492382_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005581 366.0
HFD3_k127_4492382_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006697 346.0
HFD3_k127_4492382_3 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000002238 288.0
HFD3_k127_4492382_5 export protein - - - 0.000000000000000000000000000000002104 150.0
HFD3_k127_4492382_6 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.000000000000000000000000000002899 129.0
HFD3_k127_4492382_7 G-rich domain on putative tyrosine kinase - - - 0.0000000000000000000003166 113.0
HFD3_k127_4499842_0 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000004623 176.0
HFD3_k127_4506673_0 Double sensory domain of two-component sensor kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001717 275.0
HFD3_k127_4506673_1 Homocysteine S-methyltransferase K00297,K00547,K00548 - 1.5.1.20,2.1.1.10,2.1.1.13 0.0000000000000004062 82.0
HFD3_k127_4512364_0 Histidine kinase A domain protein - - - 0.0 1402.0
HFD3_k127_4512364_1 CBS domain containing protein K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005348 590.0
HFD3_k127_4512364_2 Sigma-70 region 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 445.0
HFD3_k127_4512364_3 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000000000000251 206.0
HFD3_k127_4512364_4 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000002336 180.0
HFD3_k127_4512364_5 Vitamin K epoxide reductase family - - - 0.0000000000000000000000000000000002076 150.0
HFD3_k127_4512364_9 PFAM acyl-coA-binding protein, ACBP - - - 0.0000008472 51.0
HFD3_k127_4527899_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000006261 237.0
HFD3_k127_4527899_1 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000000000000000007864 186.0
HFD3_k127_4532158_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1545.0
HFD3_k127_4532158_1 PFAM Major Facilitator Superfamily K08177 - - 3.979e-199 630.0
HFD3_k127_4532158_2 long-chain fatty acid transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 362.0
HFD3_k127_4532158_3 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000001688 213.0
HFD3_k127_4532158_5 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000000000000000000000000000003877 122.0
HFD3_k127_453359_0 acetolactate synthase K01576,K01652 - 2.2.1.6,4.1.1.7 1.802e-308 951.0
HFD3_k127_453359_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006799 574.0
HFD3_k127_453359_2 TIGRFAM Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 301.0
HFD3_k127_453359_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 301.0
HFD3_k127_453359_4 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000001182 74.0
HFD3_k127_4554045_0 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 366.0
HFD3_k127_4554045_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 308.0
HFD3_k127_4554045_2 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001238 279.0
HFD3_k127_4554045_4 - - - - 0.00000000000000000000000000000000000000000000000000000000006475 213.0
HFD3_k127_4554045_5 maF-like protein K06287 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0047429 - 0.00000000000000000000000000000000000000000007143 179.0
HFD3_k127_4576794_0 Methyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 323.0
HFD3_k127_4576794_1 CoA-binding protein K06929 - - 0.0000000000000000000000001127 115.0
HFD3_k127_4576794_2 AraC-like ligand binding domain - - - 0.00000000000000000000002698 112.0
HFD3_k127_4576794_3 Cupin 2, conserved barrel domain protein K18991 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009438,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019243,GO:0019249,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046185,GO:0046394,GO:0051596,GO:0061727,GO:0071704,GO:0072330,GO:1901575,GO:1901576,GO:1901615,GO:1901617 - 0.0000000000000000000003601 99.0
HFD3_k127_4580838_0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0 2037.0
HFD3_k127_4580838_1 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1370.0
HFD3_k127_4580838_11 Cys-tRNA(Pro) hydrolase activity K19055 - - 0.000000000000000000000000000000000000000000000000000001437 195.0
HFD3_k127_4580838_12 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0000000000000000000000000000000000000000000000004193 193.0
HFD3_k127_4580838_13 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000004482 162.0
HFD3_k127_4580838_14 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000000000000000000001221 162.0
HFD3_k127_4580838_15 - - - - 0.0000000000000000000000000000000000000003157 161.0
HFD3_k127_4580838_16 zinc ion binding K06204 - - 0.000000000000000000000000001001 117.0
HFD3_k127_4580838_19 Outer membrane protein beta-barrel domain - - - 0.0003818 53.0
HFD3_k127_4580838_2 Transcriptional regulator, Fis family - - - 2.247e-285 892.0
HFD3_k127_4580838_3 Aminotransferase class I and II K11358 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 612.0
HFD3_k127_4580838_4 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007575 512.0
HFD3_k127_4580838_5 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009827 423.0
HFD3_k127_4580838_6 Acyl-CoA thioesterase K10805 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 355.0
HFD3_k127_4580838_7 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 324.0
HFD3_k127_4580838_8 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 302.0
HFD3_k127_4580838_9 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002626 263.0
HFD3_k127_458871_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 406.0
HFD3_k127_458871_1 spore germination K15270 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006093 382.0
HFD3_k127_458871_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009189 337.0
HFD3_k127_4630884_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 4.417e-248 773.0
HFD3_k127_4630884_1 endonuclease activity K07451 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003975 392.0
HFD3_k127_465039_0 Cellulose biosynthesis protein BcsQ K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 513.0
HFD3_k127_465039_1 deoxyhypusine monooxygenase activity - - - 0.000004239 55.0
HFD3_k127_465039_2 nuclear chromosome segregation K13582,K21471 - - 0.0006851 52.0
HFD3_k127_4659225_0 Histone deacetylase domain - - - 5.36e-263 821.0
HFD3_k127_4659225_1 Mur ligase family, catalytic domain K02558 - 6.3.2.45 3.019e-235 763.0
HFD3_k127_4659225_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 6.81e-211 657.0
HFD3_k127_4659225_3 beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004989 427.0
HFD3_k127_4659225_4 LD-carboxypeptidase K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 387.0
HFD3_k127_4659225_5 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009227 347.0
HFD3_k127_4659225_6 8 heme-binding sites - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 345.0
HFD3_k127_4659225_7 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000119 239.0
HFD3_k127_4659225_8 Thioredoxin-like - - - 0.000000000000000000005694 101.0
HFD3_k127_4659225_9 - - - - 0.00000000000000005507 94.0
HFD3_k127_4668306_0 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000005873 171.0
HFD3_k127_4668306_1 Transposase and inactivated derivatives - - - 0.000000000000000000000008642 109.0
HFD3_k127_4673460_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 1.654e-196 644.0
HFD3_k127_4673460_1 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.000000000000000000000000000000005319 131.0
HFD3_k127_4673460_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.0000000000001587 82.0
HFD3_k127_4718894_0 Pfam:DUF2029 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005492 282.0
HFD3_k127_4718894_1 YdjC-like protein - - - 0.00000000000000000000000000000000005507 139.0
HFD3_k127_4718894_2 - - - - 0.0007844 42.0
HFD3_k127_4730253_0 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 465.0
HFD3_k127_4730253_1 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 443.0
HFD3_k127_4730253_10 chromosome segregation K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001177 246.0
HFD3_k127_4730253_11 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000000000000000000000000000000000001516 230.0
HFD3_k127_4730253_12 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000000000000000000000000000000000000000006122 199.0
HFD3_k127_4730253_13 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000000000000000000007646 142.0
HFD3_k127_4730253_14 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000001316 158.0
HFD3_k127_4730253_2 repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 436.0
HFD3_k127_4730253_3 PFAM ABC transporter K01990,K01992,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 427.0
HFD3_k127_4730253_4 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003304 432.0
HFD3_k127_4730253_5 PFAM secretion protein HlyD family protein K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 376.0
HFD3_k127_4730253_6 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009346 349.0
HFD3_k127_4730253_7 chloride channel K03281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 307.0
HFD3_k127_4730253_8 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006757 276.0
HFD3_k127_4730253_9 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008249 251.0
HFD3_k127_474498_0 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005252 471.0
HFD3_k127_474498_1 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 304.0
HFD3_k127_4753070_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0 1648.0
HFD3_k127_4753070_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0 1181.0
HFD3_k127_4753070_2 PFAM UBA THIF-type NAD FAD binding protein K03148 - 2.7.7.73 1.207e-212 676.0
HFD3_k127_4753070_3 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 388.0
HFD3_k127_4753070_4 spore germination - - - 0.00000000000000000000000000000000000000000000000000000000004406 223.0
HFD3_k127_4753070_5 - - - - 0.00000000000000000000000000000000000000000002835 165.0
HFD3_k127_4753070_6 Flagellar Assembly Protein A K09749 - - 0.0000000000000000000000000000000000003242 149.0
HFD3_k127_4753070_7 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000002451 115.0
HFD3_k127_4753070_8 oxygen carrier activity K07216 - - 0.00000000000000000000001484 110.0
HFD3_k127_4753070_9 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.0000000000000000266 94.0
HFD3_k127_4770602_0 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 0.0 1295.0
HFD3_k127_4770602_1 copper-translocating P-type ATPase K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009496 491.0
HFD3_k127_4770602_2 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 472.0
HFD3_k127_4770602_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 449.0
HFD3_k127_4770602_4 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009625 443.0
HFD3_k127_4770602_5 PFAM Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 417.0
HFD3_k127_4770602_6 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003272 302.0
HFD3_k127_4770602_7 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000004532 221.0
HFD3_k127_4770602_8 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000003273 177.0
HFD3_k127_4770602_9 DNA-binding transcription factor activity K03892,K22298 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0008150,GO:0010035,GO:0010038,GO:0010045,GO:0032025,GO:0042221,GO:0050896,GO:0097159,GO:1901363 - 0.0000000000000000000000000004343 119.0
HFD3_k127_4771413_0 FeS assembly protein SufB K09014 - - 3.518e-278 867.0
HFD3_k127_4771413_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 586.0
HFD3_k127_4771413_2 FeS assembly protein SufD K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 409.0
HFD3_k127_4771413_3 FeS assembly ATPase SufC K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 388.0
HFD3_k127_4771413_4 SUF system FeS assembly protein K04488 - - 0.000000000000000000000000000000000000000000000000007337 201.0
HFD3_k127_4771413_5 transcriptional regulator, Rrf2 family - - - 0.0000000000000000000000000000000000003723 148.0
HFD3_k127_4771413_6 YaeQ - - - 0.000000000000000000002595 95.0
HFD3_k127_4778345_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003881 496.0
HFD3_k127_4791619_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 6.215e-268 879.0
HFD3_k127_4791619_1 Phosphoglucomutase K01835 - 5.4.2.2 6.815e-195 616.0
HFD3_k127_4791619_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002804 261.0
HFD3_k127_4791619_3 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000004898 234.0
HFD3_k127_4791619_4 THUMP - - - 0.00000000001309 66.0
HFD3_k127_4803005_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 4.767e-263 820.0
HFD3_k127_4803005_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 417.0
HFD3_k127_4803005_2 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 285.0
HFD3_k127_4803005_3 iron ion homeostasis K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002328 282.0
HFD3_k127_4803005_4 GGDEF domain K21009 - - 0.0000000000000000000000000000000000000000000000000000000000000001964 231.0
HFD3_k127_4803005_5 response regulator K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000008985 161.0
HFD3_k127_4812573_0 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 629.0
HFD3_k127_4812573_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 504.0
HFD3_k127_4812573_2 uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 336.0
HFD3_k127_4812573_3 polysaccharide export K01991 - - 0.0000000000000000000000000000000000000000000000000000009126 219.0
HFD3_k127_4812573_4 - - - - 0.00000000000000000000000000000000000000000003264 177.0
HFD3_k127_4812573_6 cyclic nucleotide binding K00384,K04739,K07001,K10914 - 1.8.1.9 0.000000000000000000000000000000000000002321 164.0
HFD3_k127_4812573_7 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000003246 119.0
HFD3_k127_4812573_8 COG0457 FOG TPR repeat - - - 0.0000000000002431 74.0
HFD3_k127_4814586_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1301.0
HFD3_k127_4814586_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 4.17e-220 685.0
HFD3_k127_4814586_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 563.0
HFD3_k127_4814586_3 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002395 282.0
HFD3_k127_481620_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620,K00930 - 2.3.1.1,2.3.1.35,2.7.2.8 0.0 1077.0
HFD3_k127_481620_1 regulation of single-species biofilm formation K13572,K13573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005291 449.0
HFD3_k127_481620_2 Flavin containing amine oxidoreductase K01854 - 5.4.99.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 429.0
HFD3_k127_481620_3 regulation of single-species biofilm formation K13573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 422.0
HFD3_k127_481620_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042,K18121 - 1.1.1.31,1.1.1.60,1.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005951 366.0
HFD3_k127_481620_5 Regulates arginine biosynthesis genes K03402 - - 0.000000000000000000000000000000000000000001743 179.0
HFD3_k127_481620_6 Response regulator, receiver K03413 - - 0.00000000000000000000000000000000000000002286 158.0
HFD3_k127_481620_7 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145,K05829 - 1.2.1.38 0.00000000000000179 76.0
HFD3_k127_4820749_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007473 542.0
HFD3_k127_4820749_1 RecQ zinc-binding K03654 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006056 425.0
HFD3_k127_4825823_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 4.195e-224 706.0
HFD3_k127_4825823_1 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 2.483e-198 631.0
HFD3_k127_4825823_2 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 380.0
HFD3_k127_4825823_3 TIGRFAM intracellular protease, PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 355.0
HFD3_k127_4825823_4 riboflavin synthase, alpha K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 315.0
HFD3_k127_4825823_5 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000001662 239.0
HFD3_k127_4825823_6 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000000000000000000000000162 214.0
HFD3_k127_4825823_8 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.0000000000000000000000000000000000000001421 164.0
HFD3_k127_4831611_0 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000005509 135.0
HFD3_k127_4843931_0 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004231 412.0
HFD3_k127_4843931_1 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003167 265.0
HFD3_k127_4843931_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004014 254.0
HFD3_k127_4843931_3 amine dehydrogenase activity K21449 - - 0.000000000000000000000000000000000000000000000000001488 186.0
HFD3_k127_4843931_5 PFAM ResB family protein K07399 - - 0.00000000000000000000199 110.0
HFD3_k127_4845163_0 PFAM MMPL family K07003 - - 9.803e-248 779.0
HFD3_k127_4845163_1 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 302.0
HFD3_k127_4845163_2 Protein of unknown function (DUF1295) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005643 266.0
HFD3_k127_4845163_3 short-chain dehydrogenase K07124 - - 0.0000000000000000000000000000000000000000000000000000000000000006376 236.0
HFD3_k127_4845163_5 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000003636 196.0
HFD3_k127_4845163_7 - - - - 0.000000000000007035 83.0
HFD3_k127_485117_0 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007136 561.0
HFD3_k127_485117_1 Belongs to the RimK family K05844 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016874,GO:0016879,GO:0016881,GO:0018169,GO:0018410,GO:0019538,GO:0031668,GO:0033554,GO:0036211,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070739,GO:0071496,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 401.0
HFD3_k127_485117_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 343.0
HFD3_k127_485117_3 - - - - 0.000000000000000000000000000000000000008446 162.0
HFD3_k127_485117_4 - - - - 0.0000000000001494 81.0
HFD3_k127_485117_5 - - - - 0.00001748 50.0
HFD3_k127_4856284_0 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 0.0 1065.0
HFD3_k127_4856284_1 Class II Aldolase and Adducin N-terminal domain - - - 2.668e-271 865.0
HFD3_k127_4856284_10 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000224 227.0
HFD3_k127_4856284_11 - - - - 0.00000000000000000000000000000000000000000000000001353 190.0
HFD3_k127_4856284_12 Protein of Unknown function (DUF2784) - - - 0.0000000000000000000000000000000000000002402 155.0
HFD3_k127_4856284_13 Haem-degrading - - - 0.000000000000000000000000000000003338 133.0
HFD3_k127_4856284_14 Domain of unknown function (DU1801) - - - 0.000000000000000000000006598 115.0
HFD3_k127_4856284_15 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.000000000000000000002766 102.0
HFD3_k127_4856284_16 Tetratricopeptide repeat - - - 0.000000000000007538 76.0
HFD3_k127_4856284_18 - - - - 0.00008799 55.0
HFD3_k127_4856284_2 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004807 377.0
HFD3_k127_4856284_3 Gluconolactonase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 372.0
HFD3_k127_4856284_4 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 328.0
HFD3_k127_4856284_5 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005619 282.0
HFD3_k127_4856284_6 Alpha/beta hydrolase family K07020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000202 267.0
HFD3_k127_4856284_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K20444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001846 278.0
HFD3_k127_4856284_8 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000008105 235.0
HFD3_k127_4856284_9 chlorophyll binding - - - 0.0000000000000000000000000000000000000000000000000000000000000001501 225.0
HFD3_k127_4872256_0 alpha-glucan phosphorylase K00688 - 2.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005024 376.0
HFD3_k127_487986_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 1.218e-279 878.0
HFD3_k127_487986_1 - - - - 0.00000000000000000000000000000002066 131.0
HFD3_k127_487986_2 Protein of unknown function (DUF3667) - - - 0.00000000003444 77.0
HFD3_k127_4888328_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006106 491.0
HFD3_k127_4888328_1 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007891 470.0
HFD3_k127_4888328_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 395.0
HFD3_k127_4888328_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000000000000000008057 134.0
HFD3_k127_4890870_0 Transglycosylase SLT domain K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 566.0
HFD3_k127_489670_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.0 1043.0
HFD3_k127_489670_1 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 4.455e-205 654.0
HFD3_k127_489670_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001579 254.0
HFD3_k127_489670_11 Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000004586 232.0
HFD3_k127_489670_12 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000163 186.0
HFD3_k127_489670_13 Bacterial membrane protein YfhO - - - 0.0000000000000000000000000000000000000000000000000009054 209.0
HFD3_k127_489670_14 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.0000000000000000000000000000000000000000000004823 177.0
HFD3_k127_489670_16 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000009175 162.0
HFD3_k127_489670_17 cell adhesion K02650 - - 0.0000000000000000000000000000008847 134.0
HFD3_k127_489670_18 - - - - 0.000000000000000000000000000005143 137.0
HFD3_k127_489670_2 twitching motility protein K02669 - - 9.731e-202 661.0
HFD3_k127_489670_3 Type II secretion system (T2SS), protein F K02653 - - 5.564e-196 618.0
HFD3_k127_489670_4 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00756,K00758 - 2.4.2.2,2.4.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004166 622.0
HFD3_k127_489670_5 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 557.0
HFD3_k127_489670_6 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 473.0
HFD3_k127_489670_7 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 409.0
HFD3_k127_489670_8 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 374.0
HFD3_k127_489670_9 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008837 299.0
HFD3_k127_4899177_0 endonuclease activity K07451 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 402.0
HFD3_k127_4899177_1 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.000000000000000000000000000000000000000000000000000000000000000000001423 237.0
HFD3_k127_4899177_2 Epimerase dehydratase - - - 0.000000000000000000000001145 118.0
HFD3_k127_4915941_0 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 481.0
HFD3_k127_4915941_1 energy transducer activity K03832 - - 0.0006342 51.0
HFD3_k127_4923539_0 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 2.452e-204 651.0
HFD3_k127_4923539_1 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009688 391.0
HFD3_k127_4923539_10 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00001 - 1.1.1.1 0.000000000000000003803 90.0
HFD3_k127_4923539_11 long-chain fatty acid transport protein - - - 0.0007599 52.0
HFD3_k127_4923539_2 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 374.0
HFD3_k127_4923539_3 N-terminal half of MaoC dehydratase K09709,K18291 - 4.2.1.153,4.2.1.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 342.0
HFD3_k127_4923539_4 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase K00162,K21417 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 336.0
HFD3_k127_4923539_5 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000003033 218.0
HFD3_k127_4923539_6 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000000000000000000000000003593 214.0
HFD3_k127_4923539_7 Pyruvate phosphate dikinase - - - 0.00000000000000000000000000000000000000000000000000000006929 204.0
HFD3_k127_4923539_8 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000001727 209.0
HFD3_k127_4923539_9 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8 0.000000000000000000000000000000000000000002092 179.0
HFD3_k127_4929841_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009237 478.0
HFD3_k127_4929841_1 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000005609 231.0
HFD3_k127_4929841_2 Natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000006602 186.0
HFD3_k127_4939250_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.000002687 61.0
HFD3_k127_4945588_0 lipopolysaccharide transport K04744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 600.0
HFD3_k127_4945588_1 Cation transporting ATPase, C-terminus K01531 - 3.6.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000931 570.0
HFD3_k127_4945588_2 Bacterial regulatory proteins, tetR family K13770 - - 0.000000000000000000000000000000000000000000000000000000000000000003777 258.0
HFD3_k127_4945588_3 translation initiation factor activity - - - 0.000000000000000000000000000000000000000000000196 175.0
HFD3_k127_4986566_0 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 2.676e-264 826.0
HFD3_k127_4986566_2 cell adhesion involved in biofilm formation K01186 - 3.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000001212 274.0
HFD3_k127_4986566_3 HemY protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000102 248.0
HFD3_k127_4986566_4 SCP-2 sterol transfer family - - - 0.000000000000000000000000000000000000000002826 157.0
HFD3_k127_5001553_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 9.348e-198 630.0
HFD3_k127_5001553_1 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005438 601.0
HFD3_k127_5001553_2 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000002659 269.0
HFD3_k127_5001553_3 signal peptide peptidase SppA, 36K type K04773 - - 0.000000000000000000000000000000000000000000000000000000000000003082 223.0
HFD3_k127_5001553_4 - - - - 0.00000000000000000000000000000003985 145.0
HFD3_k127_5010090_0 DEAD/H associated K03724 - - 0.0 1837.0
HFD3_k127_5010090_1 POT family K03305 - - 1.06e-225 706.0
HFD3_k127_5010090_10 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 310.0
HFD3_k127_5010090_11 chlorophyll binding K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 311.0
HFD3_k127_5010090_12 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K07444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 302.0
HFD3_k127_5010090_13 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 308.0
HFD3_k127_5010090_14 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005699 309.0
HFD3_k127_5010090_15 inorganic phosphate transmembrane transporter activity K02037,K02038 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004651 289.0
HFD3_k127_5010090_16 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004124 270.0
HFD3_k127_5010090_17 CobW/HypB/UreG, nucleotide-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004222 262.0
HFD3_k127_5010090_18 Belongs to the carbamate kinase family K00926 - 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000002672 246.0
HFD3_k127_5010090_19 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000008457 233.0
HFD3_k127_5010090_2 Proton-dependent permease that transports di- and tripeptides K03305 - - 6.037e-195 615.0
HFD3_k127_5010090_20 Domain of unknown function (DUF4442) - - - 0.0000000000000000000000000000000000000000000000000000000005969 209.0
HFD3_k127_5010090_21 cysteine-type peptidase activity - - - 0.000000000000000000000000000000000000000000002828 173.0
HFD3_k127_5010090_22 Domain of unknown function (DUF4833) - - - 0.0000000000000000000000005296 121.0
HFD3_k127_5010090_24 Belongs to the PstS family K02040 - - 0.000000000000000000003737 94.0
HFD3_k127_5010090_25 Thioredoxin-like - - - 0.0003328 44.0
HFD3_k127_5010090_3 Belongs to the methyltransferase superfamily K07444,K12297 - 2.1.1.173,2.1.1.264 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 539.0
HFD3_k127_5010090_4 Histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 449.0
HFD3_k127_5010090_5 Aminotransferase class-III K00819,K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.13,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 445.0
HFD3_k127_5010090_6 Two component transcriptional regulator, winged helix family K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003892 383.0
HFD3_k127_5010090_7 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007974 359.0
HFD3_k127_5010090_8 O-methyltransferase K00588 - 2.1.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 325.0
HFD3_k127_5010090_9 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 331.0
HFD3_k127_5020894_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 370.0
HFD3_k127_5020894_1 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007636 338.0
HFD3_k127_5020894_2 asparaginyl-tRNA synthetase K01893 - 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007006 289.0
HFD3_k127_5020894_3 Chemotaxis protein CheY K03413 - - 0.00000000000000000000000000000000000000001467 171.0
HFD3_k127_5049020_0 dehydrogenase, E1 component K00164 - 1.2.4.2 0.0 1242.0
HFD3_k127_5049020_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00627,K00658 - 2.3.1.12,2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 524.0
HFD3_k127_5049020_2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 442.0
HFD3_k127_5049020_3 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 431.0
HFD3_k127_5049020_4 to the hyi family K01816 - 5.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 336.0
HFD3_k127_5049020_5 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004062 278.0
HFD3_k127_5049020_6 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000007101 201.0
HFD3_k127_5049020_7 PFAM Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.00000000000000000000000000000000000000000000000002303 185.0
HFD3_k127_5077955_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006519 567.0
HFD3_k127_5077955_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 386.0
HFD3_k127_5077955_2 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007346 314.0
HFD3_k127_5077955_3 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007136 291.0
HFD3_k127_5097671_0 Cation transporting ATPase, C-terminus K01531 - 3.6.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 382.0
HFD3_k127_5097671_1 - - - - 0.000000000000000000000000008176 126.0
HFD3_k127_5099867_0 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 632.0
HFD3_k127_5099867_1 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 460.0
HFD3_k127_5099867_2 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000001754 155.0
HFD3_k127_5099867_3 Polysaccharide lyase family 4, domain II - - - 0.0000000000000000000000000000000000001036 149.0
HFD3_k127_5099867_4 cytochrome c - - - 0.00000000000000000000000001469 117.0
HFD3_k127_5099867_5 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000005959 118.0
HFD3_k127_5099867_6 Protein of unknown function (DUF3341) - - - 0.00000000001349 72.0
HFD3_k127_5099867_7 Phenazine biosynthesis-like protein K06998 - 5.3.3.17 0.000007789 49.0
HFD3_k127_5108555_0 PFAM PHP domain protein K02347,K04477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008717 354.0
HFD3_k127_5108555_1 TonB C terminal K03832 - - 0.00000000000000002539 89.0
HFD3_k127_5111200_0 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282,K18008 - 1.12.2.1,1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003392 540.0
HFD3_k127_5111200_1 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009693 392.0
HFD3_k127_5111200_2 OPT oligopeptide transporter protein - - - 0.000000000000000000000000000000000000001858 167.0
HFD3_k127_5111200_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000002176 144.0
HFD3_k127_5131045_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 4.133e-283 875.0
HFD3_k127_5131045_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 5.705e-203 636.0
HFD3_k127_5131045_2 NUBPL iron-transfer P-loop NTPase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 411.0
HFD3_k127_5131045_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000933 388.0
HFD3_k127_5131045_4 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 387.0
HFD3_k127_5131045_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000000000000000000000000005198 238.0
HFD3_k127_5131045_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000000000000000000000000000000002598 230.0
HFD3_k127_5131045_7 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000000000000000146 201.0
HFD3_k127_5146569_0 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 621.0
HFD3_k127_5146569_1 Rod shape-determining protein K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 393.0
HFD3_k127_5146569_2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000000000000000000000004352 166.0
HFD3_k127_5154280_0 - - - - 0.000000000000000006221 91.0
HFD3_k127_5154280_1 - - - - 0.00000004586 64.0
HFD3_k127_5163201_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 7.4e-316 981.0
HFD3_k127_5163201_1 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004238 474.0
HFD3_k127_5163201_2 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 443.0
HFD3_k127_5163201_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000002562 144.0
HFD3_k127_5176609_0 Heat shock 70 kDa protein K04043 - - 1.096e-299 924.0
HFD3_k127_5176609_1 Deoxyhypusine synthase K00809 - 2.5.1.46 8.742e-215 672.0
HFD3_k127_5176609_2 Glutamine amidotransferases class-II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 412.0
HFD3_k127_5176609_3 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 366.0
HFD3_k127_5176609_4 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009751 258.0
HFD3_k127_5176609_5 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000001122 254.0
HFD3_k127_5176609_6 toxin biosynthetic process K03558 - - 0.0000000000000001678 93.0
HFD3_k127_5176609_8 Histidine ammonia-lyase K01745 - 4.3.1.3 0.00000108 53.0
HFD3_k127_5178774_0 Malate synthase K01638 - 2.3.3.9 1.222e-240 757.0
HFD3_k127_5178774_1 dipeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 485.0
HFD3_k127_5178774_2 TIGRFAM acetylornithine and succinylornithine aminotransferase K00821,K05830,K09251 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009987,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0033094,GO:0034641,GO:0036094,GO:0042402,GO:0042802,GO:0043167,GO:0043168,GO:0044106,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:0097164,GO:1901363,GO:1901564,GO:1901565,GO:1901575 2.6.1.11,2.6.1.17,2.6.1.82 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 384.0
HFD3_k127_5178774_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009139 280.0
HFD3_k127_5178774_4 Pfam:DUF955 K07110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001167 254.0
HFD3_k127_5178774_5 dipeptidase activity - - - 0.0000003344 55.0
HFD3_k127_5178774_6 - - - - 0.0003034 46.0
HFD3_k127_5199177_0 Putative glutamine amidotransferase - - - 4.072e-281 898.0
HFD3_k127_5199177_1 DbpA RNA binding domain K03732,K05592 - 3.6.4.13 1.951e-269 843.0
HFD3_k127_5199177_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 474.0
HFD3_k127_5199177_3 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 435.0
HFD3_k127_5199177_4 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 395.0
HFD3_k127_5199177_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001508 235.0
HFD3_k127_5199177_6 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000005401 216.0
HFD3_k127_5199177_8 - - - - 0.00001482 58.0
HFD3_k127_5200644_0 Diguanylate cyclase, GGDEF domain - - - 3.012e-248 788.0
HFD3_k127_5200644_1 GTP-binding protein K06207 - - 0.00000005735 55.0
HFD3_k127_5208184_0 DnaJ molecular chaperone homology domain K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 501.0
HFD3_k127_521202_0 Two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 8.785e-249 773.0
HFD3_k127_521202_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001819 282.0
HFD3_k127_5233861_0 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 343.0
HFD3_k127_5233861_1 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000001881 138.0
HFD3_k127_5237265_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0 1431.0
HFD3_k127_5237265_1 Amino acid permease - - - 1.138e-308 960.0
HFD3_k127_5237265_2 Bacterial regulatory protein, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 403.0
HFD3_k127_5237265_3 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005831 353.0
HFD3_k127_5248770_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 2.983e-230 730.0
HFD3_k127_5248770_1 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 445.0
HFD3_k127_5248770_2 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 393.0
HFD3_k127_5248770_3 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000355 91.0
HFD3_k127_5254813_0 N-6 DNA Methylase - - - 5.864e-221 711.0
HFD3_k127_5254813_1 Capsule assembly protein Wzi - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004556 376.0
HFD3_k127_5254813_2 Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000008617 233.0
HFD3_k127_5254813_3 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.000000000000000000000000000000000000000000000000000000001961 207.0
HFD3_k127_5263287_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 4.235e-244 762.0
HFD3_k127_5263287_1 Peptidase family M28 - - - 6.653e-197 660.0
HFD3_k127_5263287_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 421.0
HFD3_k127_5263287_3 Peptidase C26 K01658,K01664 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006283 328.0
HFD3_k127_5263287_4 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000000000000000000000001169 225.0
HFD3_k127_5267055_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 9.56e-313 966.0
HFD3_k127_5267055_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 2.215e-198 622.0
HFD3_k127_5267055_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 433.0
HFD3_k127_5267055_3 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000000000000000000000000000000000006181 234.0
HFD3_k127_5267055_7 Putative methyltransferase - - - 0.0000000000000000000000000000000000319 147.0
HFD3_k127_5267055_8 Protein of unknown function (DUF533) K11962 - - 0.00000000000000002039 87.0
HFD3_k127_5269301_0 glutamine synthetase K01915 - 6.3.1.2 2.464e-285 882.0
HFD3_k127_5269301_1 Aerotolerance regulator N-terminal - - - 2.081e-248 801.0
HFD3_k127_5269301_10 ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 299.0
HFD3_k127_5269301_11 Peptidase C14, caspase catalytic - - - 0.0000000000000000000000000000000000000000000000000000000000004951 238.0
HFD3_k127_5269301_12 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000003546 186.0
HFD3_k127_5269301_13 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005488,GO:0005507,GO:0005575,GO:0005576,GO:0005615,GO:0005623,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0030288,GO:0030313,GO:0031975,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044421,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 0.0000000000000000000000000000000000000000000000000716 183.0
HFD3_k127_5269301_2 phosphorelay signal transduction system - - - 1.576e-203 649.0
HFD3_k127_5269301_3 Receptor family ligand binding region K01999 - - 1.264e-197 626.0
HFD3_k127_5269301_4 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 556.0
HFD3_k127_5269301_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 456.0
HFD3_k127_5269301_6 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009993 429.0
HFD3_k127_5269301_7 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 417.0
HFD3_k127_5269301_8 amino acid ABC transporter, ATP-binding protein K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 409.0
HFD3_k127_5269301_9 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004607 381.0
HFD3_k127_5275381_0 Aminotransferase, class V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 590.0
HFD3_k127_5275381_1 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 607.0
HFD3_k127_5275381_2 Dicarboxylate carrier MatC domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 473.0
HFD3_k127_5275381_3 Rod shape-determining protein K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 322.0
HFD3_k127_5275381_4 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000001424 73.0
HFD3_k127_5277054_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 5.839e-295 913.0
HFD3_k127_5277054_1 PFAM Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 392.0
HFD3_k127_5277054_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004261 253.0
HFD3_k127_5288721_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 383.0
HFD3_k127_5288721_1 - - - - 0.00000000000000000004171 93.0
HFD3_k127_5345943_0 7TM receptor with intracellular HD hydrolase K07037 - - 4.619e-257 818.0
HFD3_k127_5345943_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 3.723e-205 662.0
HFD3_k127_5345943_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 494.0
HFD3_k127_5345943_3 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000000000000000000000000001078 209.0
HFD3_k127_5345943_4 - - - - 0.000000000000000000000001597 112.0
HFD3_k127_5368023_0 succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004944 510.0
HFD3_k127_5368023_1 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 443.0
HFD3_k127_5368023_2 ABC transporter K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 465.0
HFD3_k127_5368023_3 Binding-protein-dependent transport system inner membrane component K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000002522 247.0
HFD3_k127_5368023_4 TIGRFAM molybdenum ABC transporter, periplasmic K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000001359 232.0
HFD3_k127_5368023_5 response to heat K07090 - - 0.0000000000000000000000000000000000000000000000000000003585 202.0
HFD3_k127_5374132_0 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 - - 1.132e-302 940.0
HFD3_k127_5374132_1 histidine kinase HAMP region domain protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 349.0
HFD3_k127_5374132_2 ABC transporter substrate binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000914 249.0
HFD3_k127_5374132_3 Ferredoxin K04755 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006790,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0022607,GO:0022900,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0055114,GO:0071840 - 0.000000000000000000000000000000000000000004083 156.0
HFD3_k127_5374132_4 Fe-S assembly protein IscX - GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772 - 0.00000000000000000000000000000009819 126.0
HFD3_k127_5394325_0 Molybdopterin oxidoreductase K00370,K17050 - 1.7.5.1 2.11e-196 621.0
HFD3_k127_5394325_1 4Fe-4S dicluster domain K00371,K17051 - 1.7.5.1 0.0000000000000003008 92.0
HFD3_k127_5395002_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 489.0
HFD3_k127_5395002_1 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004254 377.0
HFD3_k127_5395002_2 dipeptide transport K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002997 254.0
HFD3_k127_5395002_3 PFAM Radical SAM domain protein K06871 - - 0.000000000000000000000000000000000000000000000003351 190.0
HFD3_k127_5395002_5 Regulatory protein, FmdB family - - - 0.00000000000000000000000008996 110.0
HFD3_k127_539788_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2292.0
HFD3_k127_539788_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 3.186e-293 905.0
HFD3_k127_539788_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 444.0
HFD3_k127_5398618_0 glycosyl transferase family K00697 - 2.4.1.15,2.4.1.347 4.465e-286 886.0
HFD3_k127_5398618_1 methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 572.0
HFD3_k127_5398618_2 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 336.0
HFD3_k127_5398618_3 Belongs to the Dps family K04047 - - 0.00000000000000000000000000000000000000000000000000000000000000000734 228.0
HFD3_k127_5398618_4 Ferric uptake regulator family K09825 - - 0.00000000000000000000000005895 118.0
HFD3_k127_5398618_5 PFAM Rhodanese domain protein K03972 GO:0003674,GO:0003824,GO:0004792,GO:0005575,GO:0005623,GO:0016740,GO:0016782,GO:0016783,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - 0.0009127 49.0
HFD3_k127_5399087_0 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 513.0
HFD3_k127_5399087_1 PBS lyase HEAT-like repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 511.0
HFD3_k127_5399087_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001239 241.0
HFD3_k127_5399087_3 Protein of unknown function (DUF533) K11962 - - 0.0000000000000000000000000000000000000000000000000001792 195.0
HFD3_k127_5400061_0 FtsZ-dependent cytokinesis K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009316 273.0
HFD3_k127_5400061_1 Bacterial membrane protein, YfhO - - - 0.0000006779 62.0
HFD3_k127_5409327_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298 - 1.10.3.10,1.9.3.1 2.992e-268 848.0
HFD3_k127_5409327_1 Cytochrome C oxidase subunit II, transmembrane domain K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 463.0
HFD3_k127_5409327_2 4Fe-4S dicluster domain K00371,K17051 - 1.7.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 438.0
HFD3_k127_5409327_3 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 329.0
HFD3_k127_5409327_4 Mo-co oxidoreductase dimerisation domain K00387 - 1.8.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 320.0
HFD3_k127_5409327_5 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006717 312.0
HFD3_k127_5409327_6 Cytochrome c K17052 - - 0.00000000000000000000000000000000000000000000000000000000000000002393 248.0
HFD3_k127_5409327_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000007242 139.0
HFD3_k127_5409327_9 Cytochrome c - - - 0.000007527 59.0
HFD3_k127_5410667_0 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 601.0
HFD3_k127_5410667_1 Histidine kinase - - - 0.000000000000000000000000000000000007059 150.0
HFD3_k127_5410667_2 - - - - 0.000001356 51.0
HFD3_k127_5410789_0 Asparagine synthase - - - 0.000000000000000000000000000000000000000000000000004345 205.0
HFD3_k127_5410789_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.00000000000000000008944 89.0
HFD3_k127_5410789_2 (ABC) transporter - - - 0.0002309 48.0
HFD3_k127_5411067_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 423.0
HFD3_k127_5411067_1 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000000001162 216.0
HFD3_k127_5411067_2 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000000000000000000002773 104.0
HFD3_k127_5419955_0 ATPase involved in DNA repair K03546 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003175 257.0
HFD3_k127_5419955_1 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000003537 159.0
HFD3_k127_5419955_2 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000000000000006443 148.0
HFD3_k127_5429068_1 dipeptide transport K02035 - - 0.00000000000000000000007539 114.0
HFD3_k127_5445621_0 associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 346.0
HFD3_k127_5445621_1 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001359 275.0
HFD3_k127_5460988_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.254e-229 729.0
HFD3_k127_5460988_1 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000007635 154.0
HFD3_k127_5478204_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 460.0
HFD3_k127_5478204_1 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000232 224.0
HFD3_k127_5485609_0 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000001092 218.0
HFD3_k127_5485609_1 membrane - - - 0.000000000000000000000000000000000000000000000000000000000004279 232.0
HFD3_k127_5485609_2 RDD family - - - 0.0000000000000000000000000000000000000003112 165.0
HFD3_k127_5485609_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000006222 148.0
HFD3_k127_5485609_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000002443 75.0
HFD3_k127_5489375_0 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006141 394.0
HFD3_k127_5489375_1 Abc transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 381.0
HFD3_k127_5489375_2 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000006526 216.0
HFD3_k127_5489375_3 PFAM Mammalian cell entry related domain protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000001124 231.0
HFD3_k127_5489375_4 ABC-type transport auxiliary lipoprotein component K18480 - - 0.0000000000000000000000000000000000168 148.0
HFD3_k127_5506912_0 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 610.0
HFD3_k127_5506912_1 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007677 338.0
HFD3_k127_5509511_1 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 432.0
HFD3_k127_5509511_2 Flagellar Motor Protein K02557 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001268 265.0
HFD3_k127_5509511_3 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006824 251.0
HFD3_k127_5509511_4 Adenylylsulfate kinase K00860 - 2.7.1.25 0.0000000000000000000000000000000000000000000000000001688 214.0
HFD3_k127_5509511_5 Cysteine-rich domain K00113 - 1.1.5.3 0.00000000000000000000000000000000000000000001161 162.0
HFD3_k127_5511818_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 482.0
HFD3_k127_5511818_1 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000359 270.0
HFD3_k127_5511818_2 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000002346 248.0
HFD3_k127_5511818_3 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000002977 110.0
HFD3_k127_5513488_0 PFAM chemotaxis sensory transducer - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004968 601.0
HFD3_k127_5513488_1 Type IV pilus assembly protein PilM; K02461 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 585.0
HFD3_k127_5513488_2 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 455.0
HFD3_k127_5513488_3 Type II secretion system (T2SS), protein K K02460 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 334.0
HFD3_k127_5513488_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001888 272.0
HFD3_k127_5513488_5 Type II secretion system (T2SS), protein J K02459 - - 0.000000000000000000000000000000000000000000000000000000000000000001058 235.0
HFD3_k127_5513488_6 Type II secretion system (T2SS), protein M K02462 - - 0.000000000000000000000000000000000000000000000000000000001378 220.0
HFD3_k127_5530608_1 - - - - 0.000000000002765 75.0
HFD3_k127_5530608_3 OsmC-like protein - - - 0.00000000007685 65.0
HFD3_k127_5533841_0 membrane organization K03641 - - 1.212e-203 657.0
HFD3_k127_5533841_1 Belongs to the CinA family K03742,K03743 - 3.5.1.42 5.222e-195 639.0
HFD3_k127_5533841_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 430.0
HFD3_k127_5533841_3 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 368.0
HFD3_k127_5533841_4 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000001651 254.0
HFD3_k127_5533841_5 Protein conserved in bacteria K09986 - - 0.0000000000000000000000000000000000000000000000003982 179.0
HFD3_k127_5533841_7 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000005419 164.0
HFD3_k127_5540070_0 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000311 517.0
HFD3_k127_5540070_1 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000006628 197.0
HFD3_k127_5540070_2 Phosphate acyltransferases - - - 0.000000000000000000000001328 106.0
HFD3_k127_5543674_0 Male sterility protein K01897 - 6.2.1.3 0.0 1923.0
HFD3_k127_5543674_1 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 0.0 1156.0
HFD3_k127_5543674_10 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679,K01744 - 4.2.1.2,4.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 296.0
HFD3_k127_5543674_11 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000001656 229.0
HFD3_k127_5543674_12 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.0000000000000000000000000000000000000000000000000000178 203.0
HFD3_k127_5543674_14 Protein of unknown function (DUF998) - - - 0.00000000000000000000000000000000000000008518 162.0
HFD3_k127_5543674_2 Domain of unknown function (DUF2088) - - - 8.635e-299 921.0
HFD3_k127_5543674_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.991e-296 930.0
HFD3_k127_5543674_4 Cytochrome c554 and c-prime - - - 4.71e-237 744.0
HFD3_k127_5543674_5 epimerase dehydratase K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 486.0
HFD3_k127_5543674_6 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 400.0
HFD3_k127_5543674_7 ADP-glyceromanno-heptose 6-epimerase activity K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 393.0
HFD3_k127_5543674_8 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003296 367.0
HFD3_k127_5543674_9 nUDIX hydrolase K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 317.0
HFD3_k127_5550239_0 Glycosyltransferase family 28 N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005492 249.0
HFD3_k127_5552390_0 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 543.0
HFD3_k127_5552390_1 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 439.0
HFD3_k127_5552390_2 PFAM PTS system mannose fructose sorbose family IID component K02796 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009874 282.0
HFD3_k127_5552390_3 PTS system K02795 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003667 268.0
HFD3_k127_5552390_4 PFAM PTS system sorbose subfamily IIB component K02794 - 2.7.1.191 0.00000000000000000000000000000000000000000000000000000326 205.0
HFD3_k127_5552390_5 PFAM PTS system fructose subfamily IIA component K02793 - 2.7.1.191 0.0000000000000000000000000000000000000001385 167.0
HFD3_k127_5553943_0 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 299.0
HFD3_k127_5553943_1 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.00000000000000000000000000000000000000000002144 173.0
HFD3_k127_555424_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1057.0
HFD3_k127_555424_1 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 330.0
HFD3_k127_555424_2 Thioesterase superfamily - - - 0.00000000000000000000000000000001796 140.0
HFD3_k127_555424_3 Protoglobin - - - 0.00004194 54.0
HFD3_k127_5558990_0 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000001539 191.0
HFD3_k127_5561870_0 Periplasmic protein TonB links inner and outer membranes - - - 3.57e-276 865.0
HFD3_k127_5561870_1 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 587.0
HFD3_k127_5561870_2 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003547 392.0
HFD3_k127_5561870_3 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 321.0
HFD3_k127_5561870_4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003377 316.0
HFD3_k127_5561870_6 - - - - 0.00000000000000000000000000000000000000005876 157.0
HFD3_k127_5561870_7 pseudouridine synthase activity K06177,K06179,K06180 - 5.4.99.23,5.4.99.24,5.4.99.28,5.4.99.29 0.000000001774 59.0
HFD3_k127_5575220_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.000000000000000000000000000000000000000000000000000000001995 201.0
HFD3_k127_5585035_0 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000004855 273.0
HFD3_k127_5585035_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002503 261.0
HFD3_k127_5585035_2 R3H domain K06346 - - 0.000000000000000000000000000000000000000000000000000000000000000171 225.0
HFD3_k127_5586550_0 cystathionine gamma-synthase activity K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000588 534.0
HFD3_k127_5586550_1 Cyclin-dependent kinase inhibitor 3 (CDKN3) - - - 0.00000000000000000000000000000008956 130.0
HFD3_k127_5587490_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 3.961e-217 695.0
HFD3_k127_5593364_0 Sugar ABC transporter permease K10109,K15770,K15771 - - 6.803e-233 737.0
HFD3_k127_5593364_1 Alpha-amylase domain K01176 - 3.2.1.1 2.52e-212 677.0
HFD3_k127_5593364_2 Bacterial extracellular solute-binding protein K10108,K15770 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 565.0
HFD3_k127_5593364_3 Belongs to the ABC transporter superfamily K05816,K10111,K10112 - 3.6.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 522.0
HFD3_k127_5593364_4 PFAM Multi antimicrobial extrusion protein MatE K03327 - - 0.0000000000000000000000000000000001136 135.0
HFD3_k127_5593364_5 Binding-protein-dependent transport system inner membrane component K10110,K15772 - - 0.00000000003723 78.0
HFD3_k127_559778_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.906e-228 721.0
HFD3_k127_559778_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 4.966e-227 737.0
HFD3_k127_559778_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 490.0
HFD3_k127_559778_3 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000599 267.0
HFD3_k127_559778_4 acetyltransferase - - - 0.00000000000000000000000000000000000000000000001911 192.0
HFD3_k127_559778_5 Protein of unknown function (DUF1232) - - - 0.00000000000000000000000000000000000000000000003594 190.0
HFD3_k127_559778_6 Transcription factor zinc-finger K09981 - - 0.0000000000000000000000000000000000004406 154.0
HFD3_k127_559778_7 zinc-ribbon domain - - - 0.000000000000000000000000000000000001055 148.0
HFD3_k127_559778_8 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000001229 116.0
HFD3_k127_5598697_0 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 321.0
HFD3_k127_5598697_1 peptidase M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004699 324.0
HFD3_k127_5598697_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006317 312.0
HFD3_k127_5598697_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 301.0
HFD3_k127_5601282_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 2.378e-271 847.0
HFD3_k127_5601282_1 Domain of unknown function (DUF4388) - - - 1.682e-199 640.0
HFD3_k127_5601282_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000641 69.0
HFD3_k127_5601391_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 4.457e-315 989.0
HFD3_k127_5601391_1 PFAM Extracellular ligand-binding receptor K01999 - - 4.738e-197 623.0
HFD3_k127_5601391_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 538.0
HFD3_k127_5601391_3 Belongs to the binding-protein-dependent transport system permease family K01997,K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008048 461.0
HFD3_k127_5601391_4 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 424.0
HFD3_k127_5601391_5 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 383.0
HFD3_k127_5601391_6 PFAM CBS domain containing protein K04767 - - 0.00000000000000000000000000000000000000000000000000000025 200.0
HFD3_k127_5601391_7 Gram-negative porin - - - 0.000000000000000000000003636 117.0
HFD3_k127_5612930_0 Elongator protein 3, MiaB family, Radical SAM - - - 1.812e-196 623.0
HFD3_k127_5612930_1 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007261 607.0
HFD3_k127_5612930_2 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.0000000000000000000000000000000000000000000000003256 177.0
HFD3_k127_5612930_3 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000001585 103.0
HFD3_k127_5612930_4 cheY-homologous receiver domain - - - 0.0000000000000000001045 96.0
HFD3_k127_5648888_0 Efflux ABC transporter, permease ATP-binding protein K06147 - - 0.00000000000000000000000000000000000000000001101 182.0
HFD3_k127_5659781_0 peptidase S9A, prolyl oligopeptidase domain protein beta-propeller K01322 - 3.4.21.26 2.966e-307 956.0
HFD3_k127_5661809_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 525.0
HFD3_k127_5661809_1 N-succinyltransferase beta subunit K00673 - 2.3.1.109 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 471.0
HFD3_k127_5661809_2 Peptidase dimerisation domain K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000444 433.0
HFD3_k127_5661809_3 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009493 422.0
HFD3_k127_5661809_4 PFAM ABC transporter related K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005072 357.0
HFD3_k127_5661809_5 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 323.0
HFD3_k127_5661809_6 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000003315 216.0
HFD3_k127_5661809_7 HIT domain K02503 - - 0.000000000000000000000000000000000000000000003583 168.0
HFD3_k127_5668726_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 550.0
HFD3_k127_5668726_1 DAHP synthetase I family K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 455.0
HFD3_k127_5677794_0 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 607.0
HFD3_k127_5677794_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 469.0
HFD3_k127_5677794_10 hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000000007042 203.0
HFD3_k127_5677794_11 BFD-like [2Fe-2S] binding domain - - - 0.0000000000000000000000000000000000000000000007041 191.0
HFD3_k127_5677794_12 hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000002194 168.0
HFD3_k127_5677794_13 PFAM Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000004296 163.0
HFD3_k127_5677794_15 - - - - 0.000000000000000000000000000000003359 130.0
HFD3_k127_5677794_16 Periplasmic binding protein K01999 - - 0.00000000000000000002881 104.0
HFD3_k127_5677794_17 YsiA-like protein, C-terminal region - - - 0.0000000000000000146 91.0
HFD3_k127_5677794_2 PFAM Transketolase K21417 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000999 375.0
HFD3_k127_5677794_3 Dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009147 348.0
HFD3_k127_5677794_4 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 319.0
HFD3_k127_5677794_5 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 334.0
HFD3_k127_5677794_6 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 303.0
HFD3_k127_5677794_7 PFAM regulatory protein TetR - - - 0.00000000000000000000000000000000000000000000000000000000000000000005239 239.0
HFD3_k127_5677794_8 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000001499 221.0
HFD3_k127_5677794_9 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000681 217.0
HFD3_k127_569037_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 1.132e-266 832.0
HFD3_k127_569037_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 595.0
HFD3_k127_569037_2 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.000000000000000000000000115 112.0
HFD3_k127_5690571_1 long-chain fatty acid transport protein - - - 0.00000000000000000000000000000000000000000000002658 191.0
HFD3_k127_5700351_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 2.526e-221 702.0
HFD3_k127_5700351_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003392 453.0
HFD3_k127_5700351_2 PFAM Major facilitator superfamily K08224 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 415.0
HFD3_k127_5700351_3 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.000000000000000000000000000000001233 145.0
HFD3_k127_5700902_0 Bacterial protein of unknown function (DUF853) K06915 - - 4.746e-204 647.0
HFD3_k127_5700902_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 6.944e-197 622.0
HFD3_k127_5700902_10 - - - - 0.000000000000000000000172 104.0
HFD3_k127_5700902_11 Uncharacterised protein family UPF0066 - - - 0.00000000000000000005905 102.0
HFD3_k127_5700902_12 Putative esterase - - - 0.0000000000003417 69.0
HFD3_k127_5700902_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 552.0
HFD3_k127_5700902_3 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 528.0
HFD3_k127_5700902_4 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 394.0
HFD3_k127_5700902_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 343.0
HFD3_k127_5700902_6 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003576 325.0
HFD3_k127_5700902_7 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001177 273.0
HFD3_k127_5700902_8 - - - - 0.00000000000000000000000000000000000000000000005372 189.0
HFD3_k127_5700902_9 - - - - 0.000000000000000000000000000000006203 145.0
HFD3_k127_570317_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 1.076e-232 735.0
HFD3_k127_570317_1 Ubiquinol-cytochrome C reductase - - - 0.000000000000000000000000000000000000000000962 162.0
HFD3_k127_570317_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03117 - - 0.000007581 49.0
HFD3_k127_5704266_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1030.0
HFD3_k127_5704266_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 499.0
HFD3_k127_5704266_2 HAD-hyrolase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002698 290.0
HFD3_k127_5704266_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000005633 227.0
HFD3_k127_5707888_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 474.0
HFD3_k127_5707888_1 DNA-dependent DNA replication K02315,K04076 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 399.0
HFD3_k127_5707888_2 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 359.0
HFD3_k127_5727151_0 TonB C terminal K03832 - - 0.000000000000000000000000000000000000000000000003365 182.0
HFD3_k127_5727151_1 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000003262 178.0
HFD3_k127_5744805_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 4.964e-255 792.0
HFD3_k127_5763630_0 ABC-2 family transporter protein K19341 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004827 382.0
HFD3_k127_5763630_1 lipoprotein involved in nitrous oxide reduction K19342 - - 0.0000000000000000000000000000000000000000000000001385 184.0
HFD3_k127_5763630_2 COG2335 Secreted and surface protein containing fasciclin-like repeats - - - 0.0000000000000000000000000000000000000006847 154.0
HFD3_k127_5763630_3 ABC transporter K01990,K19340 - - 0.0000000000000000000001034 106.0
HFD3_k127_5771926_0 iron-sulfur binding K00184 - - 0.0 1137.0
HFD3_k127_5771926_1 Polysulphide reductase, NrfD K00185 - - 9.084e-209 701.0
HFD3_k127_5771926_10 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000002018 136.0
HFD3_k127_5771926_11 methyltransferase activity K13613,K15677 - - 0.000000000000000000000000000002398 138.0
HFD3_k127_5771926_2 cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 527.0
HFD3_k127_5771926_3 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298 - 1.10.3.10,1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 449.0
HFD3_k127_5771926_4 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 462.0
HFD3_k127_5771926_5 Putative zinc-finger K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 421.0
HFD3_k127_5771926_6 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005838 298.0
HFD3_k127_5771926_7 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004478 261.0
HFD3_k127_5771926_8 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000005584 207.0
HFD3_k127_5771926_9 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000000000000000000215 197.0
HFD3_k127_5778003_0 Peptidase family M3 K01392 - 3.4.24.15 1.983e-220 691.0
HFD3_k127_5778003_1 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000007011 166.0
HFD3_k127_5778003_2 Membrane - - - 0.00008193 56.0
HFD3_k127_5787849_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 5.111e-258 801.0
HFD3_k127_5787849_1 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 6.286e-199 624.0
HFD3_k127_5787849_2 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000000000000001322 184.0
HFD3_k127_5806890_0 CoA binding domain K09181 - - 1.594e-315 1000.0
HFD3_k127_5806890_1 Alpha beta hydrolase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 314.0
HFD3_k127_5806890_2 UbiA prenyltransferase family K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000863 262.0
HFD3_k127_5806890_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008791 275.0
HFD3_k127_5806890_4 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003459 253.0
HFD3_k127_5806890_5 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000532 176.0
HFD3_k127_5806890_6 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000001086 123.0
HFD3_k127_5806890_7 PFAM CBS domain containing protein K04767 - - 0.00000000000000000000000000000216 131.0
HFD3_k127_5806890_8 transcriptional regulator - - - 0.000004691 55.0
HFD3_k127_5812073_0 gamma-glutamylcyclotransferase activity - - - 0.00000000000000000000000000000000000000000000000000000005812 200.0
HFD3_k127_5812073_1 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000004874 191.0
HFD3_k127_5812073_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000003492 182.0
HFD3_k127_5812073_3 Domain of unknown function (DUF1992) - - - 0.00000000000000000000000000000009975 131.0
HFD3_k127_5812073_4 Tetratricopeptide repeat - - - 0.0000000000007601 79.0
HFD3_k127_5830409_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 451.0
HFD3_k127_5830409_1 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 328.0
HFD3_k127_5830409_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000000000002371 197.0
HFD3_k127_5830409_4 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000002271 83.0
HFD3_k127_5834261_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005954 426.0
HFD3_k127_5842244_0 tRNA nucleotidyltransferase domain 2 putative K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009461 427.0
HFD3_k127_5842244_1 His Kinase A (phosphoacceptor) domain - - - 0.00009998 48.0
HFD3_k127_5847627_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07538 - 1.1.1.368 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 519.0
HFD3_k127_5847627_1 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.00000000000000000000000000000000000000000003135 164.0
HFD3_k127_584869_0 epimerase dehydratase K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 364.0
HFD3_k127_584869_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007493 291.0
HFD3_k127_584869_11 Redoxin K03564 - 1.11.1.15 0.00000000008296 71.0
HFD3_k127_584869_2 - - - - 0.000000000000000000000000000000000000000000000167 176.0
HFD3_k127_584869_3 Membrane - - - 0.0000000000000000000000000000000000000000005169 164.0
HFD3_k127_584869_4 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000003132 147.0
HFD3_k127_584869_5 Transcriptional Regulator, AraC family - - - 0.00000000000000000000000000000002621 134.0
HFD3_k127_584869_6 Response regulator, receiver - - - 0.00000000000000000000000002252 117.0
HFD3_k127_584869_8 Cytochrome P460 - - - 0.000000000000000000009444 97.0
HFD3_k127_584869_9 Phospholipase_D-nuclease N-terminal - - - 0.00000000000000006875 82.0
HFD3_k127_5850034_0 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 470.0
HFD3_k127_5850034_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006932 328.0
HFD3_k127_5850034_2 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000006824 228.0
HFD3_k127_5850034_3 - - - - 0.000000000000000000000000000000000000000000000000000000000111 211.0
HFD3_k127_5850034_4 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000001499 194.0
HFD3_k127_5850034_5 - - - - 0.0000000000000000000000000000000000000000000003464 175.0
HFD3_k127_5850034_6 - - - - 0.0000000000000000000000027 109.0
HFD3_k127_5850034_7 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000002182 98.0
HFD3_k127_5850034_8 - - - - 0.000000000002428 80.0
HFD3_k127_5850034_9 Putative regulatory protein - - - 0.00000000005176 67.0
HFD3_k127_5866136_0 - - - - 5.216e-214 678.0
HFD3_k127_5866136_1 OPT oligopeptide transporter protein - - - 1.759e-213 671.0
HFD3_k127_5866136_2 - - - - 0.000000000000000000000000000000000000002072 169.0
HFD3_k127_5886774_0 DegT/DnrJ/EryC1/StrS aminotransferase family K13010,K19430 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 623.0
HFD3_k127_5886774_10 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000298 143.0
HFD3_k127_5886774_11 - - - - 0.000000000000000000000000000001389 141.0
HFD3_k127_5886774_12 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000007737 135.0
HFD3_k127_5886774_13 methyltransferase - - - 0.0000000000000004343 90.0
HFD3_k127_5886774_14 Uncharacterized conserved protein (DUF2304) K09153 - - 0.0000004655 57.0
HFD3_k127_5886774_2 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006635 464.0
HFD3_k127_5886774_3 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 368.0
HFD3_k127_5886774_4 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 365.0
HFD3_k127_5886774_5 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 311.0
HFD3_k127_5886774_6 Glycosyl transferase family 2 K00721,K00786 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000005201 231.0
HFD3_k127_5886774_7 COG0463 Glycosyltransferases involved in cell wall biogenesis K13002 - - 0.0000000000000000000000000000000000000000000000000000000000000007628 243.0
HFD3_k127_5886774_8 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000003183 158.0
HFD3_k127_5886774_9 acetyltransferase K03789 - 2.3.1.128 0.000000000000000000000000000000000009512 144.0
HFD3_k127_588851_0 hydrogenase large subunit K14126 - 1.8.98.5 3.972e-215 696.0
HFD3_k127_588851_1 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006711 404.0
HFD3_k127_588851_2 Thioredoxin-like [2Fe-2S] ferredoxin K00334,K03388 - 1.6.5.3,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000001141 271.0
HFD3_k127_588851_3 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002685 252.0
HFD3_k127_588851_4 Domain in cystathionine beta-synthase and other proteins. K06041 - 5.3.1.13 0.00000000000000000000000000000000000111 155.0
HFD3_k127_588851_5 Hydrogenase maturation protease K00442 - - 0.00000000000000000000000000000000001962 155.0
HFD3_k127_588851_6 Fe-S cluster domain protein - - - 0.0000000000000000000003837 108.0
HFD3_k127_5895584_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679,K01744 - 4.2.1.2,4.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004735 497.0
HFD3_k127_5895584_1 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.00000000000000000000000000000000000000000000000001472 205.0
HFD3_k127_5895584_2 amine dehydrogenase activity - - - 0.00000002643 67.0
HFD3_k127_5895650_0 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000002629 201.0
HFD3_k127_5895650_1 Protein of unknown function (DUF1800) - - - 0.000000000001315 79.0
HFD3_k127_5896383_0 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 477.0
HFD3_k127_5896383_1 Domain of unknown function (DUF4037) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000271 254.0
HFD3_k127_5896383_2 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 0.000000000000000000000000000000001238 138.0
HFD3_k127_5906094_0 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 446.0
HFD3_k127_5906094_1 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000002103 233.0
HFD3_k127_5906094_2 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000001305 235.0
HFD3_k127_5906094_4 Protein of unknown function (FYDLN_acid) - - - 0.0000000000000000002458 101.0
HFD3_k127_5906931_0 PFAM Pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 394.0
HFD3_k127_5906931_1 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002551 281.0
HFD3_k127_5906931_2 Putative transmembrane protein (Alph_Pro_TM) - - - 0.00000000002273 79.0
HFD3_k127_5906931_3 Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.00000001143 63.0
HFD3_k127_5915658_0 Pyruvate flavodoxin ferredoxin K00174 - 1.2.7.11,1.2.7.3 1.642e-301 935.0
HFD3_k127_5915658_1 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 314.0
HFD3_k127_5915658_2 YtxH-like protein - - - 0.0005025 51.0
HFD3_k127_5948570_0 Glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1857.0
HFD3_k127_5948570_1 Cytochrome P460 - - - 0.000000000000000000000000000000000000000000000000000000000000002567 228.0
HFD3_k127_5963912_0 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000000000000002744 211.0
HFD3_k127_5963912_1 Uncharacterised nucleotidyltransferase - - - 0.00000000000000000000000000000000125 143.0
HFD3_k127_5984884_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1167.0
HFD3_k127_5984884_1 Protein of unknown function (DUF475) K09799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 416.0
HFD3_k127_5984884_2 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000006118 267.0
HFD3_k127_5984884_3 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000007197 249.0
HFD3_k127_5984884_4 - - - - 0.00000000000000000000000000000000000000001634 175.0
HFD3_k127_5985361_0 carboxylase K01969,K13778 - 6.4.1.4,6.4.1.5 1.389e-237 757.0
HFD3_k127_5985361_1 PFAM Carbamoyl-phosphate synthase L chain K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 538.0
HFD3_k127_5985361_2 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.000000000000002569 85.0
HFD3_k127_59884_0 PFAM aminotransferase class I and II K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 600.0
HFD3_k127_59884_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00322 - 1.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 368.0
HFD3_k127_5995477_0 uridine kinase K00876 - 2.7.1.48 3.871e-297 927.0
HFD3_k127_5995477_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 341.0
HFD3_k127_5996941_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005797 565.0
HFD3_k127_5996941_1 Peptidase family M23 K21471 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008025 419.0
HFD3_k127_6006936_0 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 575.0
HFD3_k127_6006936_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 398.0
HFD3_k127_6006936_2 Domain of unknown function (DUF4912) K09942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 306.0
HFD3_k127_6018048_0 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 400.0
HFD3_k127_6018048_2 - - - - 0.00000000000000000000003997 103.0
HFD3_k127_6018048_3 iron-sulfur cluster assembly - - - 0.00000000000001271 74.0
HFD3_k127_6068252_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1354.0
HFD3_k127_6068252_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000004786 159.0
HFD3_k127_6073565_0 Acyl-CoA dehydrogenase N terminal K00248 - 1.3.8.1 1.445e-269 841.0
HFD3_k127_6073565_1 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 1.009e-244 766.0
HFD3_k127_6073565_10 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000002494 172.0
HFD3_k127_6073565_11 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000008963 170.0
HFD3_k127_6073565_12 PFAM Hemerythrin HHE cation binding domain protein K07216 - - 0.00000000000000000000000000000000008031 142.0
HFD3_k127_6073565_13 metallopeptidase activity - - - 0.000000000000000000000000002385 130.0
HFD3_k127_6073565_15 LysM domain - - - 0.0000002136 65.0
HFD3_k127_6073565_2 AsmA family K07289 - - 2.859e-226 731.0
HFD3_k127_6073565_3 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007155 309.0
HFD3_k127_6073565_4 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003141 286.0
HFD3_k127_6073565_5 ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002017 279.0
HFD3_k127_6073565_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001124 269.0
HFD3_k127_6073565_7 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000009835 250.0
HFD3_k127_6073565_8 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000007533 244.0
HFD3_k127_6073565_9 Domain of unknown function (DUF3943) - - - 0.000000000000000000000000000000000000000000000000000000000001065 225.0
HFD3_k127_6081899_0 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 400.0
HFD3_k127_6081899_1 Domain of unknown function (DUF3943) - - - 0.000000000000000000000000000000000000000000000000000000000000000000002555 258.0
HFD3_k127_6081899_2 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000000000000000000000000000000002253 216.0
HFD3_k127_6081899_3 Predicted membrane protein (DUF2339) - - - 0.0000000000000000000000001006 123.0
HFD3_k127_6102318_0 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001193 241.0
HFD3_k127_6102318_1 Chalcone isomerase-like - - - 0.00000000000000000000000000000000000000000000000001078 190.0
HFD3_k127_6102318_2 Flagellar Assembly Protein A K09749 - - 0.00000001162 65.0
HFD3_k127_6138728_0 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 353.0
HFD3_k127_6138728_1 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000003434 205.0
HFD3_k127_6138728_2 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.00000000000000000000000000000000000000000000004732 172.0
HFD3_k127_6138728_3 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000002663 162.0
HFD3_k127_6140655_0 [isocitrate dehydrogenase (NADP+)] phosphatase activity K00906 GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004721,GO:0004722,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009060,GO:0009987,GO:0015980,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0016999,GO:0017076,GO:0017144,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046487,GO:0050790,GO:0055114,GO:0065007,GO:0065009,GO:0070262,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 606.0
HFD3_k127_6140655_1 Alcohol dehydrogenase GroES domain protein K19745 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 473.0
HFD3_k127_6140655_2 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007213 448.0
HFD3_k127_6140655_3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 393.0
HFD3_k127_6140655_4 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 375.0
HFD3_k127_6140655_5 Thioesterase superfamily K02614 - - 0.000000000000000000000000000197 134.0
HFD3_k127_6142302_0 asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 1.28e-314 975.0
HFD3_k127_6142302_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.895e-249 781.0
HFD3_k127_6142302_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474,K13015 - 1.1.1.136 4.605e-228 712.0
HFD3_k127_6142302_3 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 494.0
HFD3_k127_6142302_5 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000007698 255.0
HFD3_k127_6142302_6 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000008427 211.0
HFD3_k127_6148904_0 - - - - 0.00000000000000000000000000000000000000000000000008407 188.0
HFD3_k127_6164604_0 heat shock protein binding - - - 4.702e-265 839.0
HFD3_k127_617325_0 PFAM Integrase catalytic region - - - 0.000000000000000000000000000000000000000000000000000000000000000001314 244.0
HFD3_k127_6206082_0 4Fe-4S dicluster domain K18930 - - 0.0 1227.0
HFD3_k127_6206082_1 cluster binding protein K18929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 619.0
HFD3_k127_6206082_10 Thiamine-binding protein - - - 0.000000000000000000000000000000000000000000944 167.0
HFD3_k127_6206082_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 528.0
HFD3_k127_6206082_3 Diadenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000478 415.0
HFD3_k127_6206082_4 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 373.0
HFD3_k127_6206082_5 PFAM Cysteine-rich domain K18928 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 338.0
HFD3_k127_6206082_6 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 299.0
HFD3_k127_6206082_7 histone H2A K63-linked ubiquitination - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004687 266.0
HFD3_k127_6206082_8 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000000000000000000000000000000000000005845 209.0
HFD3_k127_6206082_9 LUD domain K00782 - - 0.00000000000000000000000000000000000000000001148 184.0
HFD3_k127_6214420_0 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 542.0
HFD3_k127_6214420_1 Alpha beta hydrolase - - - 0.000000000000000000000000000000000001189 150.0
HFD3_k127_6214420_2 Protein of unknown function (DUF1015) - - - 0.0000000000008923 68.0
HFD3_k127_6222876_0 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008066 491.0
HFD3_k127_6222876_1 Conserved protein containing a Zn-ribbon-like motif possibly RNA-binding - - - 0.0000000000000000000000000000000000000000000000000000000009436 207.0
HFD3_k127_6222876_2 GDP-mannose mannosyl hydrolase activity K03574 - 3.6.1.55 0.0000000000000000002673 99.0
HFD3_k127_6222876_3 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.00000000000000321 83.0
HFD3_k127_6228639_0 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 478.0
HFD3_k127_6228639_1 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005994 436.0
HFD3_k127_6228639_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 374.0
HFD3_k127_6228639_3 branched-chain amino acid K01995 - - 0.00000000001135 64.0
HFD3_k127_6229862_0 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 2.581e-296 925.0
HFD3_k127_6229862_1 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006789 327.0
HFD3_k127_6229862_2 TIGRFAM Molybdopterin-guanine dinucleotide biosynthesis protein B K03753 - - 0.000000000000000000000000000000000000000000007075 166.0
HFD3_k127_6229862_3 Sigma-54 interaction domain - - - 0.0000000000000000000000001038 108.0
HFD3_k127_6237379_0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 1.39e-292 907.0
HFD3_k127_6237379_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 562.0
HFD3_k127_6237379_2 Acetyl-coenzyme A transporter 1 K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008696 529.0
HFD3_k127_6237379_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 347.0
HFD3_k127_6237379_5 Thioredoxin-like [2Fe-2S] ferredoxin - - - 0.00000000000000000000005116 116.0
HFD3_k127_6244659_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 1.933e-275 856.0
HFD3_k127_6244659_1 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000602 499.0
HFD3_k127_6244659_2 Methyltransferase type 11 K03892 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 363.0
HFD3_k127_6244659_3 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006928 348.0
HFD3_k127_6244659_4 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000004866 119.0
HFD3_k127_6244659_5 Peptidase MA superfamily - - - 0.0000000000001483 80.0
HFD3_k127_6254124_0 Ammonium Transporter Family K03320 - - 1.128e-196 623.0
HFD3_k127_6254124_1 Pfam:Kce K18013 - 2.3.1.247 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008908 292.0
HFD3_k127_6254124_3 Belongs to the bacterial histone-like protein family K03530 - - 0.0000000000000000000000000000000000001017 143.0
HFD3_k127_6287465_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343 422.0
HFD3_k127_6287465_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000001744 252.0
HFD3_k127_6287465_2 photosystem II stabilization K02237,K02238,K02719 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009523,GO:0009579,GO:0016020,GO:0030075,GO:0030096,GO:0032991,GO:0034357,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797 - 0.000000000000000000000000003845 128.0
HFD3_k127_6287465_3 Histidine ammonia-lyase K01745 - 4.3.1.3 0.000000000000000000001417 95.0
HFD3_k127_6287465_4 Amidohydrolase family - - - 0.000000000000002958 85.0
HFD3_k127_6287465_5 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000005406 80.0
HFD3_k127_6288201_0 Domain of Unknown Function (DUF748) - - - 1.45e-221 724.0
HFD3_k127_6288201_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006535 442.0
HFD3_k127_6288201_2 tRNA synthetases class I (W and Y) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007475 365.0
HFD3_k127_6290726_0 AAA C-terminal domain K07478 - - 2.606e-220 689.0
HFD3_k127_6290726_1 Histidine kinase A domain protein K02482 - 2.7.13.3 3.424e-218 689.0
HFD3_k127_6290726_2 Sigma-54 interaction domain K07713,K07714,K07715 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009905 531.0
HFD3_k127_6290726_3 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006779 402.0
HFD3_k127_6290726_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 385.0
HFD3_k127_6290726_5 Uncharacterised protein family (UPF0227) K07000 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006987 296.0
HFD3_k127_6290726_6 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.00000000000000000000000000000000000000000000000008329 185.0
HFD3_k127_6290726_7 Belongs to the D-alanine--D-alanine ligase family - - - 0.00000000000000000000000000000000000000005918 153.0
HFD3_k127_6290726_8 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000003498 135.0
HFD3_k127_6297042_0 Belongs to the enoyl-CoA hydratase isomerase family K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.0 1008.0
HFD3_k127_6297042_1 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000009289 164.0
HFD3_k127_6311030_0 domain protein K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 506.0
HFD3_k127_6311030_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 465.0
HFD3_k127_6311030_2 Belongs to the sulfate adenylyltransferase family K00958,K13811 - 2.7.1.25,2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 433.0
HFD3_k127_6311030_3 Catalyzes the synthesis of activated sulfate K00390,K00860 - 1.8.4.10,1.8.4.8,2.7.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006867 305.0
HFD3_k127_6311030_4 Mo-molybdopterin cofactor metabolic process K03636,K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000001033 116.0
HFD3_k127_6311030_5 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000007856 112.0
HFD3_k127_631239_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 2.311e-255 794.0
HFD3_k127_631239_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 3.458e-231 721.0
HFD3_k127_631239_10 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000001042 136.0
HFD3_k127_631239_11 - - - - 0.000000001551 61.0
HFD3_k127_631239_12 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000009906 58.0
HFD3_k127_631239_13 SMART Rhodanese domain protein - - - 0.00000419 49.0
HFD3_k127_631239_2 homoserine dehydrogenase K00003 - 1.1.1.3 3.282e-214 681.0
HFD3_k127_631239_3 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008923 530.0
HFD3_k127_631239_4 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 317.0
HFD3_k127_631239_5 YceI-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009689 258.0
HFD3_k127_631239_7 negative regulation of translational initiation - - - 0.000000000000000000000000000000000000000000000000000000000000000001425 229.0
HFD3_k127_631239_8 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000000000000000000000000001243 219.0
HFD3_k127_631239_9 Histidine kinase - - - 0.000000000000000000000000000000000000000000001284 177.0
HFD3_k127_6317634_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 325.0
HFD3_k127_6317634_1 Enoyl-(Acyl carrier protein) reductase K03793 - 1.5.1.33 0.0000000000000000000000000000000000000000000000000000000000001451 214.0
HFD3_k127_6317634_2 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000000000000000000000245 184.0
HFD3_k127_6317634_3 SCP / Tpx-1 / Ag5 / PR-1 / Sc7 family of extracellular domains. - - - 0.000000000000000000000000000000000006871 149.0
HFD3_k127_6317634_4 Serine Threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000002054 96.0
HFD3_k127_6319024_0 Asparagine synthase K01953 - 6.3.5.4 0.0 1088.0
HFD3_k127_6319024_1 domain, Protein - - - 1.158e-252 805.0
HFD3_k127_6319024_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 385.0
HFD3_k127_6319024_11 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 350.0
HFD3_k127_6319024_12 dehydrogenases and related proteins K18652 - 1.1.1.361 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 352.0
HFD3_k127_6319024_13 Belongs to the glycosyltransferase 26 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002159 258.0
HFD3_k127_6319024_14 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008011 259.0
HFD3_k127_6319024_15 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002083 254.0
HFD3_k127_6319024_16 PFAM Acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001729 259.0
HFD3_k127_6319024_17 polysaccharide export K01991 - - 0.000000000000000000000000000000000000000000000000005438 205.0
HFD3_k127_6319024_18 DUF218 domain - - - 0.00000000000000000000000000000001585 138.0
HFD3_k127_6319024_19 Phosphopantetheine attachment site - - - 0.000000000000000000000001997 120.0
HFD3_k127_6319024_2 PFAM Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 614.0
HFD3_k127_6319024_20 PilZ domain - - - 0.000000000000001233 81.0
HFD3_k127_6319024_23 - - - - 0.0000000001388 74.0
HFD3_k127_6319024_25 Polysaccharide deacetylase - - - 0.0000001222 65.0
HFD3_k127_6319024_26 Transposase DDE domain - - - 0.000001029 57.0
HFD3_k127_6319024_3 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007146 571.0
HFD3_k127_6319024_4 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007079 544.0
HFD3_k127_6319024_5 -O-antigen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004932 526.0
HFD3_k127_6319024_6 MBOAT, membrane-bound O-acyltransferase family K19294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007531 505.0
HFD3_k127_6319024_7 Sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 474.0
HFD3_k127_6319024_8 Pectate lyase superfamily protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 451.0
HFD3_k127_6319024_9 extracellular polysaccharide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004832 425.0
HFD3_k127_6319605_0 Cys Met metabolism K01739,K01758,K01761 - 2.5.1.48,4.4.1.1,4.4.1.11 1.045e-206 651.0
HFD3_k127_63397_0 Formate dehydrogenase N, transmembrane K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 352.0
HFD3_k127_63397_1 formate dehydrogenase K00127 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002845 269.0
HFD3_k127_63397_2 Necessary for formate dehydrogenase activity K02380 - - 0.000000000000000000000000000000000000000000000001093 194.0
HFD3_k127_6341207_0 FAD linked oxidase domain protein - - - 4.085e-315 977.0
HFD3_k127_6341207_1 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005781 294.0
HFD3_k127_6341207_2 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000005024 196.0
HFD3_k127_6347957_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 461.0
HFD3_k127_6347957_1 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007804 251.0
HFD3_k127_6347957_2 PAS sensor protein - - - 0.000000000000000000000000000000000000000000000000009451 183.0
HFD3_k127_6347957_3 1,4-alpha-glucan branching enzyme activity K00700 - 2.4.1.18 0.0000000000000000000000000000000000000000000000001163 193.0
HFD3_k127_6358012_0 Putative metal-binding motif - - - 0.0 1200.0
HFD3_k127_6358012_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 2.707e-235 747.0
HFD3_k127_6358012_2 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 317.0
HFD3_k127_6358012_4 protein import - - - 0.000000000000000000000000000000000000000007616 171.0
HFD3_k127_6358012_5 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000001772 168.0
HFD3_k127_6358012_6 - - - - 0.0000000000000000000001878 115.0
HFD3_k127_6360305_0 Nad-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005922 353.0
HFD3_k127_6360305_1 Histidine kinase HAMP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003837 279.0
HFD3_k127_6360305_10 PFAM FecR protein - - - 0.00001465 57.0
HFD3_k127_6360305_2 cobalamin binding K03496,K22491 - - 0.0000000000000000000000000000000000000000000000000008718 195.0
HFD3_k127_6360305_3 adenosine 5'-monophosphoramidase activity - - - 0.00000000000000000000000000000000000000000000000192 181.0
HFD3_k127_6360305_4 PAP2 superfamily - - - 0.0000000000000000000000000000000000000000001275 171.0
HFD3_k127_6360305_5 - K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.00000000000000000000000000001539 123.0
HFD3_k127_6360305_6 cheY-homologous receiver domain - - - 0.00000000000000000005346 95.0
HFD3_k127_6360305_8 Peptidase family M28 - - - 0.0000000000000001961 89.0
HFD3_k127_6360305_9 FecR protein - - - 0.00000000000007154 86.0
HFD3_k127_6361852_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008234 453.0
HFD3_k127_6361852_1 endonuclease activity K07451 - - 0.000000000000000000000000000002231 124.0
HFD3_k127_6361852_2 Domain of unknown function (DUF4265) - - - 0.000000000000004311 85.0
HFD3_k127_6381707_0 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 449.0
HFD3_k127_6381707_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 442.0
HFD3_k127_6381707_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 357.0
HFD3_k127_6381707_3 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 358.0
HFD3_k127_6381707_4 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 318.0
HFD3_k127_6381707_6 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001067 253.0
HFD3_k127_6381707_7 FHA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002267 253.0
HFD3_k127_6381707_8 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000003773 239.0
HFD3_k127_6381707_9 regulation of DNA repair K03565 - - 0.0000000000000000000000000000000000000206 160.0
HFD3_k127_6384662_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 574.0
HFD3_k127_6384662_1 PFAM 2-nitropropane dioxygenase NPD K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 448.0
HFD3_k127_6384662_10 Biotin carboxylase K01941,K01959 - 6.3.4.6,6.4.1.1 0.0000003862 59.0
HFD3_k127_6384662_11 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.0000671 52.0
HFD3_k127_6384662_2 beta-keto acid cleavage enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 340.0
HFD3_k127_6384662_3 PFAM Extracellular ligand-binding receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007524 339.0
HFD3_k127_6384662_4 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001306 281.0
HFD3_k127_6384662_5 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000002631 250.0
HFD3_k127_6384662_6 PFAM ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000006866 247.0
HFD3_k127_6384662_7 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000007804 222.0
HFD3_k127_6384662_8 COG0559 Branched-chain amino acid ABC-type transport system, permease components K01997 - - 0.000000000000000000000000000000000000000000000000000005715 201.0
HFD3_k127_6384662_9 enoyl-CoA hydratase - - - 0.0000000000000000006343 87.0
HFD3_k127_6396571_0 Catalyzes the synthesis of activated sulfate K00390,K00860 - 1.8.4.10,1.8.4.8,2.7.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000006151 268.0
HFD3_k127_6396571_1 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000001297 208.0
HFD3_k127_6396571_2 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 0.00000000000000000000000000000000000000000000004177 181.0
HFD3_k127_6411202_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 3.754e-206 646.0
HFD3_k127_6411202_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 468.0
HFD3_k127_6411202_2 Transporter associated domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007284 394.0
HFD3_k127_6411202_3 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000002334 216.0
HFD3_k127_6411202_4 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000001506 224.0
HFD3_k127_6432318_0 3'(2'),5'-bisphosphate nucleotidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 471.0
HFD3_k127_6432318_1 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000154 230.0
HFD3_k127_6432575_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 8.396e-286 885.0
HFD3_k127_6432575_1 Biotin-lipoyl like K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 564.0
HFD3_k127_6432575_2 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000003857 193.0
HFD3_k127_6437824_0 PFAM Xanthine uracil vitamin C permease K06901 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008872 574.0
HFD3_k127_6437824_1 Uracil phosphoribosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 449.0
HFD3_k127_6437824_2 PFAM peptidase - - - 0.000000000000000000000000000109 124.0
HFD3_k127_6461606_0 AAA domain K10742 - 3.6.4.12 1.251e-258 806.0
HFD3_k127_6461606_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 3.631e-214 673.0
HFD3_k127_6461606_2 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 400.0
HFD3_k127_6461606_3 RNase_H superfamily K07502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 380.0
HFD3_k127_6462897_0 Belongs to the glycosyl hydrolase 13 family K01200 - 3.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 499.0
HFD3_k127_6462897_1 oxidoreductase - - - 0.000000000000000000000000000000000000000000000000001406 199.0
HFD3_k127_6462897_2 Psort location Cytoplasmic, score K01759,K03827 - 4.4.1.5 0.00000000000000000000000000002126 135.0
HFD3_k127_6462897_3 Alpha-amylase domain K01176 - 3.2.1.1 0.0000000000000000009148 87.0
HFD3_k127_6462897_4 Bacterial pullanase-associated domain - - - 0.00000000000000006736 80.0
HFD3_k127_6475261_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006323 581.0
HFD3_k127_6475261_1 Mycolic acid cyclopropane synthetase K00574,K20238 - 2.1.1.317,2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 429.0
HFD3_k127_6475261_2 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000478 289.0
HFD3_k127_6479287_0 lysine biosynthetic process via aminoadipic acid - - - 5.371e-217 702.0
HFD3_k127_6479287_1 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 627.0
HFD3_k127_6479287_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 569.0
HFD3_k127_6479287_3 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 541.0
HFD3_k127_6479287_4 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000007776 172.0
HFD3_k127_6479287_5 Belongs to the helicase family. UvrD subfamily - - - 0.00000000000000000000000000000000000000000002713 165.0
HFD3_k127_6482669_0 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 4.756e-274 848.0
HFD3_k127_6482669_1 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 617.0
HFD3_k127_6482669_2 Pyridoxal-dependent decarboxylase conserved domain K01634 - 4.1.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006178 525.0
HFD3_k127_6482669_3 PFAM amidohydrolase K20810 - 3.5.4.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 410.0
HFD3_k127_6482669_4 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 389.0
HFD3_k127_6482669_5 Belongs to the GbsR family - - - 0.00000000000000000000000000000000000000000000000000000000000000004862 250.0
HFD3_k127_6482669_6 S-adenosylhomocysteine deaminase activity K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000329 113.0
HFD3_k127_6493394_0 Belongs to the FPP GGPP synthase family K00805,K02523 - 2.5.1.30,2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009738 486.0
HFD3_k127_6493394_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 364.0
HFD3_k127_6493394_2 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 362.0
HFD3_k127_6493394_3 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000035 143.0
HFD3_k127_649432_0 AMP-binding enzyme K01897 - 6.2.1.3 6.374e-288 894.0
HFD3_k127_649432_1 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 3.394e-234 730.0
HFD3_k127_649432_10 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 290.0
HFD3_k127_649432_11 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 296.0
HFD3_k127_649432_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001414 289.0
HFD3_k127_649432_13 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000001292 264.0
HFD3_k127_649432_14 PHB/PHA accumulation regulator DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000003322 235.0
HFD3_k127_649432_15 - - - - 0.000000000000000000000000000000000000000000000000000000000000001457 230.0
HFD3_k127_649432_16 PFAM Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000005994 177.0
HFD3_k127_649432_17 zinc-ribbon domain - - - 0.000000000000000000000000000000000000000005159 173.0
HFD3_k127_649432_18 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000003502 68.0
HFD3_k127_649432_2 Protein of unknown function, DUF255 K06888 - - 8.066e-225 706.0
HFD3_k127_649432_3 ubiquinol oxidase subunit I K00425 - 1.10.3.14 1.321e-200 634.0
HFD3_k127_649432_4 Amidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004386 589.0
HFD3_k127_649432_5 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 539.0
HFD3_k127_649432_6 oxidase, subunit K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 436.0
HFD3_k127_649432_7 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 426.0
HFD3_k127_649432_8 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 379.0
HFD3_k127_649432_9 Chromosome Partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 358.0
HFD3_k127_6500476_0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 315.0
HFD3_k127_6500476_1 PFAM ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000002068 256.0
HFD3_k127_6500476_2 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000000000000000000000000000000002651 185.0
HFD3_k127_6500476_3 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000945 184.0
HFD3_k127_6500476_4 MacB-like periplasmic core domain - - - 0.00000000000000000000000000001248 138.0
HFD3_k127_6500476_5 - - - - 0.000000000000000003752 99.0
HFD3_k127_6510174_0 General secretory system II, protein E domain protein K02454 - - 0.0 1034.0
HFD3_k127_6510174_1 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 1.809e-289 919.0
HFD3_k127_6510174_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 304.0
HFD3_k127_6510174_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007249 267.0
HFD3_k127_6510174_12 FR47-like protein K03789 - 2.3.1.128 0.000000000000000000000000000000000000000000000000000008971 204.0
HFD3_k127_6510174_13 lytic transglycosylase activity - - - 0.0000000000000000000000000000000000000000000000002195 185.0
HFD3_k127_6510174_16 Domain of unknown function (DUF4386) - - - 0.0000000000000000000000000000000002258 153.0
HFD3_k127_6510174_18 Uncharacterized conserved protein (DUF2277) - - - 0.00000000000000000000006807 105.0
HFD3_k127_6510174_19 Regulatory protein, FmdB family - - - 0.0000000000000000004593 89.0
HFD3_k127_6510174_2 peptidase S9B dipeptidylpeptidase IV domain protein K01278 - 3.4.14.5 5.958e-245 777.0
HFD3_k127_6510174_3 ATPase family associated with various cellular activities (AAA) - - - 5.981e-216 709.0
HFD3_k127_6510174_4 acetyl-CoA hydrolase K18118 - 2.8.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 593.0
HFD3_k127_6510174_5 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004325 483.0
HFD3_k127_6510174_6 DnaJ C terminal domain K03686,K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007955 459.0
HFD3_k127_6510174_7 Inositol monophosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007168 368.0
HFD3_k127_6510174_8 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009766 344.0
HFD3_k127_6510174_9 lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005245 330.0
HFD3_k127_6510424_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004179 294.0
HFD3_k127_6510424_1 glutathione transferase activity K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000004294 255.0
HFD3_k127_6510424_2 SnoaL-like domain - - - 0.0000000000000000000000000000000001857 136.0
HFD3_k127_6510424_3 NfeD-like C-terminal, partner-binding - - - 0.000000000000000000003286 95.0
HFD3_k127_6510424_4 SnoaL-like domain - - - 0.000000001181 61.0
HFD3_k127_6512873_0 Electron transfer flavoprotein K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 489.0
HFD3_k127_6512873_1 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 450.0
HFD3_k127_6512873_2 Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000976 435.0
HFD3_k127_6512873_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003845 419.0
HFD3_k127_6512873_4 Membrane protein, TerC - - - 0.00000000000000000000000000000000000000000000003106 174.0
HFD3_k127_6512873_5 metallopeptidase activity K01183 - 3.2.1.14 0.0001168 55.0
HFD3_k127_6521674_0 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005196 501.0
HFD3_k127_6521674_1 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 317.0
HFD3_k127_6521674_2 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000001165 190.0
HFD3_k127_6521674_3 THUMP - - - 0.0000000000000000000000000000000000000000000006633 173.0
HFD3_k127_6521674_4 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.00000000000000001883 82.0
HFD3_k127_6539955_0 PFAM Band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 472.0
HFD3_k127_6539955_1 NAD dependent epimerase/dehydratase family K05281 - 1.3.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005767 445.0
HFD3_k127_6539955_2 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 388.0
HFD3_k127_6539955_3 ATP ADP translocase K03301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 349.0
HFD3_k127_6539955_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009744 241.0
HFD3_k127_6539955_5 NfeD-like C-terminal, partner-binding - - - 0.00000000000000000000000000558 112.0
HFD3_k127_6545596_0 reductase alpha subunit K00394 - 1.8.99.2 5.79e-317 979.0
HFD3_k127_6545596_1 Heterodisulfide reductase subunit A and related polyferredoxins K16886 - - 8.767e-223 734.0
HFD3_k127_6545596_10 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.0000000000000000000000000000000000000000000000000000001722 209.0
HFD3_k127_6545596_11 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000007308 199.0
HFD3_k127_6545596_12 Transcriptional regulator - - - 0.0000000000000000000000000000000007083 143.0
HFD3_k127_6545596_13 Function of homologous gene experimentally demonstrated in an other organism K21703 - - 0.00000000000000000000000000000005086 138.0
HFD3_k127_6545596_14 Ogr/Delta-like zinc finger - - - 0.000001281 62.0
HFD3_k127_6545596_2 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 587.0
HFD3_k127_6545596_3 TIGRFAM sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 558.0
HFD3_k127_6545596_4 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 484.0
HFD3_k127_6545596_5 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008458 488.0
HFD3_k127_6545596_6 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 450.0
HFD3_k127_6545596_7 FAD dependent oxidoreductase K16885 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 368.0
HFD3_k127_6545596_8 reductase beta subunit K00395 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000961 237.0
HFD3_k127_6545596_9 4Fe-4S dicluster domain K16887 - - 0.000000000000000000000000000000000000000000000000000000000000000004466 239.0
HFD3_k127_6546950_1 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004857 394.0
HFD3_k127_6557470_0 AMP-binding enzyme - - - 8.64e-232 731.0
HFD3_k127_6561841_0 Malate synthase K01638 - 2.3.3.9 0.0 1230.0
HFD3_k127_6561939_0 May be involved in recombinational repair of damaged DNA K03631 - - 1.628e-230 728.0
HFD3_k127_6561939_1 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004918 494.0
HFD3_k127_6561939_2 peptidase M24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 445.0
HFD3_k127_6561939_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009049 386.0
HFD3_k127_6561939_4 protein phosphatase 2C domain protein K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009049 374.0
HFD3_k127_6561939_5 Bacterial capsule synthesis protein PGA_cap - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006682 316.0
HFD3_k127_6561939_6 cysteine-type peptidase activity K21471,K21473,K21687 - - 0.0000000000000000000000000000000000002883 151.0
HFD3_k127_6568271_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 4.892e-292 919.0
HFD3_k127_6568271_1 Biotin carboxylase C-terminal domain K01941,K01961 - 6.3.4.14,6.3.4.6,6.4.1.2 1.697e-237 745.0
HFD3_k127_6568271_2 Biotin-requiring enzyme - - - 0.00000000000000000000000000000000000000000000000002761 202.0
HFD3_k127_6576180_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 612.0
HFD3_k127_6576180_1 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000000000000000000000000000000000005507 189.0
HFD3_k127_6588272_0 Bacterial regulatory protein, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 423.0
HFD3_k127_6588272_1 Enoyl-(Acyl carrier protein) reductase K16066 - 1.1.1.381 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 351.0
HFD3_k127_6589447_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 4.504e-216 693.0
HFD3_k127_6606517_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 295.0
HFD3_k127_6606517_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006586 272.0
HFD3_k127_660677_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 2.21e-298 925.0
HFD3_k127_660677_1 PFAM peptidase U62 modulator of DNA gyrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 589.0
HFD3_k127_660677_2 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 520.0
HFD3_k127_660677_3 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 402.0
HFD3_k127_660677_4 endonuclease activity K07451 - - 0.000000000000000000000000000000000000000000000000000000000008533 217.0
HFD3_k127_660677_5 UPF0056 inner membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000000002244 225.0
HFD3_k127_660677_6 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.0000000000000007175 91.0
HFD3_k127_660677_7 hydrolase activity, hydrolyzing N-glycosyl compounds - - - 0.0000008307 55.0
HFD3_k127_6610811_0 MMPL family - - - 1.061e-232 739.0
HFD3_k127_6610811_1 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000003672 204.0
HFD3_k127_6634936_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.0 1159.0
HFD3_k127_6634936_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 5.231e-204 661.0
HFD3_k127_6634936_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000001514 201.0
HFD3_k127_6634936_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000000000000000003333 179.0
HFD3_k127_6634936_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000000000000000001709 165.0
HFD3_k127_6634936_13 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000000000008034 135.0
HFD3_k127_6634936_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 5.993e-204 638.0
HFD3_k127_6634936_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004766 588.0
HFD3_k127_6634936_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K05580 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 337.0
HFD3_k127_6634936_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 318.0
HFD3_k127_6634936_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009531 319.0
HFD3_k127_6634936_7 Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000333 296.0
HFD3_k127_6634936_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002 278.0
HFD3_k127_6634936_9 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000001043 246.0
HFD3_k127_6650006_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 571.0
HFD3_k127_6650006_1 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 420.0
HFD3_k127_6650006_2 PFAM FAD linked oxidase domain protein K00104,K11472 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 419.0
HFD3_k127_6650006_3 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002748 265.0
HFD3_k127_6650018_0 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 610.0
HFD3_k127_6650018_1 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 451.0
HFD3_k127_6650018_2 Cytochrome c - - - 0.0000006066 51.0
HFD3_k127_6653383_0 Putative modulator of DNA gyrase K03568 - - 2.023e-250 786.0
HFD3_k127_6653383_1 Putative modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005762 592.0
HFD3_k127_6653383_2 - - - - 0.0000000000001855 71.0
HFD3_k127_6653383_3 PFAM Prolyl oligopeptidase family - - - 0.000000000001819 74.0
HFD3_k127_6654539_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1056.0
HFD3_k127_6654539_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 550.0
HFD3_k127_6654539_10 FecR protein - - - 0.0000000000000000000000000002744 132.0
HFD3_k127_6654539_11 Protein of unknown function (DUF1566) - - - 0.0000002377 62.0
HFD3_k127_6654539_2 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004479 360.0
HFD3_k127_6654539_3 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007585 319.0
HFD3_k127_6654539_4 domain, Protein K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000002885 255.0
HFD3_k127_6654539_5 Uncharacterized conserved protein (DUF2183) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001307 252.0
HFD3_k127_6654539_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.0000000000000000000000000000000000000000000000000000001322 201.0
HFD3_k127_6654539_7 - - - - 0.00000000000000000000000000000000000000000000000000000536 213.0
HFD3_k127_6654539_8 - - - - 0.0000000000000000000000000000000000000000000004968 177.0
HFD3_k127_6654539_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000004834 185.0
HFD3_k127_6678938_0 Peptidase family S58 K01266 - 3.4.11.19 3.64e-209 666.0
HFD3_k127_6678938_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009485 333.0
HFD3_k127_6695219_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 5.252e-219 687.0
HFD3_k127_6695219_1 VWA domain containing CoxE-like protein K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 569.0
HFD3_k127_6695219_2 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006351 298.0
HFD3_k127_6695219_3 PFAM ABC transporter related K05776 - - 0.00000000000000000000000000000000000000000000000000000000000000000006893 243.0
HFD3_k127_6695219_4 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000001515 229.0
HFD3_k127_6695219_6 PFAM Cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000000000000000000003795 207.0
HFD3_k127_6695219_7 - - - - 0.0000000000000003602 93.0
HFD3_k127_6699094_0 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 364.0
HFD3_k127_6699094_1 oligosaccharyl transferase activity - - - 0.000002597 61.0
HFD3_k127_6699222_0 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 595.0
HFD3_k127_6699222_1 COG1233 Phytoene dehydrogenase and related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005927 501.0
HFD3_k127_6699222_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 328.0
HFD3_k127_6699222_3 CHASE2 K01768 - 4.6.1.1 0.0000000002651 66.0
HFD3_k127_6715377_0 Heat shock 70 kDa protein K04043 - - 0.0 1060.0
HFD3_k127_6715377_1 ABC-type branched-chain amino acid transport K07121 - - 3.105e-224 714.0
HFD3_k127_6715377_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005755 518.0
HFD3_k127_6715377_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007912 484.0
HFD3_k127_6715377_4 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 382.0
HFD3_k127_6715377_5 photosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001739 257.0
HFD3_k127_6715377_6 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000003497 252.0
HFD3_k127_6717498_0 TIGRFAM cytochrome C family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001844 280.0
HFD3_k127_6717498_1 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001173 242.0
HFD3_k127_6717498_2 trisaccharide binding - - - 0.00000000000000000000000000000000000000000000000000000000000000973 223.0
HFD3_k127_6717498_3 - - - - 0.00000000000000000000001188 115.0
HFD3_k127_6720123_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666 - - 1.514e-222 702.0
HFD3_k127_6720123_1 Stage II sporulation protein - - - 0.000000000000000000000000000001161 121.0
HFD3_k127_672888_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 374.0
HFD3_k127_672888_1 - - - - 0.0000000000000000000000000000000000000000000005284 167.0
HFD3_k127_672888_2 sequence-specific DNA binding - - - 0.0000000000000000000000000000000003239 134.0
HFD3_k127_6743509_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003913 367.0
HFD3_k127_6743509_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007709 307.0
HFD3_k127_6743509_2 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000000000000000000000001435 132.0
HFD3_k127_6743509_3 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000001596 116.0
HFD3_k127_6743509_4 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000004919 64.0
HFD3_k127_6761276_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 516.0
HFD3_k127_6761276_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 421.0
HFD3_k127_6761276_2 Formamidopyrimidine-DNA glycosylase N-terminal domain K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003919 355.0
HFD3_k127_6761276_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000002021 214.0
HFD3_k127_6772996_0 Belongs to the D-alanine--D-alanine ligase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006973 518.0
HFD3_k127_6772996_1 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000007441 238.0
HFD3_k127_6772996_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K03793 - 1.5.1.33 0.000000000000000000000001901 106.0
HFD3_k127_680029_0 PFAM AMP-dependent synthetase and ligase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004849 309.0
HFD3_k127_680029_1 Probable molybdopterin binding domain K03742 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000001489 267.0
HFD3_k127_680029_2 Quinolinate phosphoribosyl transferase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000304 209.0
HFD3_k127_680029_3 MaoC like domain - - - 0.000000000001691 73.0
HFD3_k127_680029_4 N-terminal half of MaoC dehydratase - - - 0.00000007545 65.0
HFD3_k127_6801743_0 Protein of unknown function (DUF2400) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 413.0
HFD3_k127_6801743_1 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000000001555 254.0
HFD3_k127_6801743_2 nitrite reductase [NAD(P)H] activity K05710 - - 0.0000000000000000000000001015 111.0
HFD3_k127_6806847_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 433.0
HFD3_k127_6806847_1 Alpha amylase, catalytic domain K01208,K01218 - 3.2.1.133,3.2.1.135,3.2.1.54,3.2.1.78 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 302.0
HFD3_k127_6806847_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000004483 235.0
HFD3_k127_6811537_0 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404 610.0
HFD3_k127_6811537_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 518.0
HFD3_k127_6811537_2 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 418.0
HFD3_k127_6811537_3 PFAM permease YjgP YjgQ family protein K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 367.0
HFD3_k127_6811537_4 PFAM permease YjgP YjgQ family protein K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007701 375.0
HFD3_k127_6811537_5 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000001323 262.0
HFD3_k127_6811537_6 DNA-templated transcription, initiation K03088,K11333 - 1.3.7.14,1.3.7.15 0.00000000000000000000000000000000000000000000000004059 192.0
HFD3_k127_6811537_7 Belongs to the SUA5 family K07566 - 2.7.7.87 0.00000000000000000000000000000000001723 150.0
HFD3_k127_6811537_8 zinc-ribbon domain - - - 0.0008835 51.0
HFD3_k127_6812387_0 CHASE2 K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000003056 279.0
HFD3_k127_6822788_0 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009156,GO:0009161,GO:0009163,GO:0009164,GO:0009165,GO:0009167,GO:0009168,GO:0009987,GO:0015949,GO:0015950,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0032261,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0043173,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 569.0
HFD3_k127_6822788_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 370.0
HFD3_k127_6846151_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 2.67e-242 756.0
HFD3_k127_6846151_1 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 601.0
HFD3_k127_6846151_2 PFAM UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005113 558.0
HFD3_k127_6846151_3 Pyridoxal-phosphate dependent enzyme K12339 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 406.0
HFD3_k127_6846151_4 1-Cys peroxiredoxin K11188 - 1.11.1.15,1.11.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006134 325.0
HFD3_k127_6846151_5 cytochrome c K15876 - - 0.000000000000000000000000000000000000000000000000001372 202.0
HFD3_k127_6846151_6 Mov34 MPN PAD-1 - - - 0.000000000000000000000000000000000000000002334 173.0
HFD3_k127_6846151_7 ThiS family K03636 - - 0.00000000000000000000000001909 118.0
HFD3_k127_6848461_0 Heat shock 70 kDa protein K04043 - - 3.573e-282 878.0
HFD3_k127_6860347_0 PFAM Three-deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 2.08e-210 663.0
HFD3_k127_6860347_1 PFAM glycosyl transferase family 9 K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 436.0
HFD3_k127_6860347_2 PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 397.0
HFD3_k127_6860347_3 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000881 297.0
HFD3_k127_6860347_4 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.00000000000000000000000117 104.0
HFD3_k127_6867558_0 histone H2A K63-linked ubiquitination K03466 - - 0.000000000000000000000000000000000000002514 159.0
HFD3_k127_6867558_1 Carbohydrate family 9 binding domain-like - - - 0.00000000000000000000000000000002731 139.0
HFD3_k127_6867558_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000001033 131.0
HFD3_k127_6867711_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 583.0
HFD3_k127_6867711_1 Sigma-70, region 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002648 257.0
HFD3_k127_6867711_2 MerR HTH family regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000353 191.0
HFD3_k127_6867711_3 protein kinase activity K08884 - 2.7.11.1 0.00000000000000000408 88.0
HFD3_k127_6877213_0 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 548.0
HFD3_k127_6877213_1 Winged helix DNA-binding domain - - - 0.00000000000000000000000001226 115.0
HFD3_k127_6884949_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 513.0
HFD3_k127_6884949_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001715 274.0
HFD3_k127_6888863_0 AcrB/AcrD/AcrF family - - - 0.0 1028.0
HFD3_k127_6888863_1 ABC transporter, ATP-binding protein - - - 3.957e-273 856.0
HFD3_k127_6888863_10 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 365.0
HFD3_k127_6888863_11 TRAP transporter T-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 353.0
HFD3_k127_6888863_12 thiolester hydrolase activity K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 319.0
HFD3_k127_6888863_13 Uracil DNA glycosylase superfamily K03648 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001554 286.0
HFD3_k127_6888863_14 PAP2 superfamily C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000297 270.0
HFD3_k127_6888863_15 OmpA family K02557 - - 0.0000000000000000000000000000000000000000000000000000000000000000184 235.0
HFD3_k127_6888863_16 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.0000000000000000000000000000000000000000000000000000000000000007679 230.0
HFD3_k127_6888863_17 OmpA family K02557 - - 0.0000000000000000000000000000000000000000000000000000003158 204.0
HFD3_k127_6888863_18 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K07444 - - 0.00000000000000000000000000000002062 129.0
HFD3_k127_6888863_19 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000006968 136.0
HFD3_k127_6888863_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 7.402e-238 752.0
HFD3_k127_6888863_20 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000005071 119.0
HFD3_k127_6888863_21 methyltransferase - - - 0.0000000001698 73.0
HFD3_k127_6888863_22 Outer membrane efflux protein K12340 - - 0.0000003878 65.0
HFD3_k127_6888863_23 E1-E2 ATPase K17686 - 3.6.3.54 0.000008596 49.0
HFD3_k127_6888863_3 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008416 608.0
HFD3_k127_6888863_4 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 486.0
HFD3_k127_6888863_5 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 434.0
HFD3_k127_6888863_6 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 428.0
HFD3_k127_6888863_7 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004205 441.0
HFD3_k127_6888863_9 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 374.0
HFD3_k127_6906272_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 1.542e-255 803.0
HFD3_k127_6906272_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000004187 177.0
HFD3_k127_6906272_2 Psort location CytoplasmicMembrane, score - - - 0.0000001297 59.0
HFD3_k127_6913348_0 Acyl-CoA dehydrogenase, C-terminal domain K00249,K11731 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008995 594.0
HFD3_k127_6913348_1 CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000000000000000000001893 158.0
HFD3_k127_6915657_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1348.0
HFD3_k127_6915657_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798,K04076,K13525,K17681 - 3.4.21.53 1.569e-233 756.0
HFD3_k127_6915657_2 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 7.829e-224 702.0
HFD3_k127_6915657_3 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000516 611.0
HFD3_k127_6915657_4 COG1335 Amidases related to nicotinamidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009589 495.0
HFD3_k127_6915657_5 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 356.0
HFD3_k127_6915657_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000003822 243.0
HFD3_k127_6915657_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000003435 208.0
HFD3_k127_6918332_0 PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal K14534 - 4.2.1.120,5.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 553.0
HFD3_k127_6918332_1 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 376.0
HFD3_k127_6918332_2 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 342.0
HFD3_k127_6918332_3 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 346.0
HFD3_k127_6918332_4 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 286.0
HFD3_k127_6918332_5 amino acid K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001048 305.0
HFD3_k127_6918332_6 Amino acid amide ABC transporter ATP-binding protein 2, HAAT family K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001692 290.0
HFD3_k127_6918332_7 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.0000000000000000000000000000000000000000000000008949 177.0
HFD3_k127_6922077_0 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000005251 231.0
HFD3_k127_6922077_1 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.00000000000000000000000000000000000003381 153.0
HFD3_k127_6922077_2 Acyl-CoA dehydrogenase, middle domain - - - 0.00000000000000000001115 106.0
HFD3_k127_6932033_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 627.0
HFD3_k127_6932033_1 beta-galactosidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009681 510.0
HFD3_k127_6932033_2 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 519.0
HFD3_k127_6932033_3 PFAM Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007929 439.0
HFD3_k127_6932033_4 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 399.0
HFD3_k127_6932033_5 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000002337 235.0
HFD3_k127_6932033_6 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.0000000000000000000000000000000000000000000000001018 204.0
HFD3_k127_6932033_7 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000001336 62.0
HFD3_k127_6932033_8 Putative transposase - - - 0.000006599 59.0
HFD3_k127_6934214_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 1.819e-228 719.0
HFD3_k127_6934214_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 7.112e-220 695.0
HFD3_k127_6934214_2 N-terminal domain of unknown function (DUF4140) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 568.0
HFD3_k127_6934214_3 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 392.0
HFD3_k127_6934214_4 Glutamine amidotransferases class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 314.0
HFD3_k127_6934214_5 Protein of unknown function DUF99 K09120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 295.0
HFD3_k127_6934214_6 protein family UPF0079, ATPase K06925 - - 0.0000000000000000000000000000000000000000000000000000000006034 226.0
HFD3_k127_6934214_7 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000000009247 156.0
HFD3_k127_6938124_0 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 473.0
HFD3_k127_6938124_1 ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 387.0
HFD3_k127_6938124_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000003507 230.0
HFD3_k127_6938124_4 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.0000000000000000000000000000000000004254 143.0
HFD3_k127_6958780_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1396.0
HFD3_k127_6958780_1 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008412 490.0
HFD3_k127_6958780_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 420.0
HFD3_k127_6958780_3 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 413.0
HFD3_k127_6958780_4 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000008054 151.0
HFD3_k127_6962735_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000001107 116.0
HFD3_k127_6969144_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0 1043.0
HFD3_k127_6969144_1 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 306.0
HFD3_k127_6969144_2 Ribosomal protein L11 methyltransferase (PrmA) K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000006524 241.0
HFD3_k127_6969144_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.000009006 55.0
HFD3_k127_6987250_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 8.935e-274 849.0
HFD3_k127_6987250_1 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005632 528.0
HFD3_k127_6987250_2 PFAM ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 400.0
HFD3_k127_6987250_3 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 339.0
HFD3_k127_6987250_4 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002599 248.0
HFD3_k127_6987250_5 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000000000000001626 222.0
HFD3_k127_6987250_6 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.000000000000000000000000000000000000000000000000000004808 196.0
HFD3_k127_6987250_7 lipopolysaccharide transport K09774 - - 0.000000000000000000000000000006251 127.0
HFD3_k127_6987250_8 - K01865 - 5.4.4.1 0.00000000000000000000003164 104.0
HFD3_k127_6988284_0 RDD family K18481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 298.0
HFD3_k127_6988547_0 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 368.0
HFD3_k127_6988547_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009117 290.0
HFD3_k127_6988547_2 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000003687 172.0
HFD3_k127_6988547_3 Hexapeptide repeat of succinyl-transferase - - - 0.000000000000000000000000000000002322 139.0
HFD3_k127_6988547_4 - - - - 0.0000000000000000000000000001597 129.0
HFD3_k127_6988547_5 - - - - 0.0000000000000000000000000005486 130.0
HFD3_k127_6988641_0 response regulator K07714 - - 2.124e-209 659.0
HFD3_k127_6988641_1 Helix-turn-helix XRE-family like proteins - - - 0.0000000001046 63.0
HFD3_k127_6988641_2 Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.0000001571 64.0
HFD3_k127_6992530_0 heat shock protein binding - - - 2.854e-217 715.0
HFD3_k127_6992530_1 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 4.784e-198 631.0
HFD3_k127_6992530_2 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005443 295.0
HFD3_k127_6992530_3 heat shock protein binding - - - 0.000000000000000000000000003551 128.0
HFD3_k127_6994278_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 5.987e-271 838.0
HFD3_k127_6994278_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006312 384.0
HFD3_k127_7006134_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007905 469.0
HFD3_k127_7006134_1 Protein of unknown function (DUF1295) - - - 0.000000000000000000000000000000000000000000000000000000000000000000007501 259.0
HFD3_k127_7006134_2 PFAM Short-chain dehydrogenase reductase SDR K07124 - - 0.0000000000000000000000000000000000000000000000000000000000000006596 238.0
HFD3_k127_7006134_3 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.0000000000000000000000000000000000000000000000000000000007324 207.0
HFD3_k127_7006134_5 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000001014 132.0
HFD3_k127_7006134_6 transcriptional regulator K13643 - - 0.0000000000000000000002559 101.0
HFD3_k127_7006134_7 YMGG-like Gly-zipper - - - 0.0000000000000005187 82.0
HFD3_k127_7006134_8 - - - - 0.000000000004123 74.0
HFD3_k127_7006134_9 Hemerythrin HHE cation binding domain - - - 0.000000002486 64.0
HFD3_k127_7006217_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 3.92e-285 890.0
HFD3_k127_7006217_1 peptidase U62 modulator of DNA gyrase - - - 2.132e-253 796.0
HFD3_k127_7006217_10 peptide catabolic process K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000001632 248.0
HFD3_k127_7006217_11 - - - - 0.0000000000000000000000002177 108.0
HFD3_k127_7006217_13 - - - - 0.00003081 55.0
HFD3_k127_7006217_14 SpoVT / AbrB like domain - - - 0.0000893 47.0
HFD3_k127_7006217_2 Sarcosine oxidase K00303 - 1.5.3.1 9.863e-223 715.0
HFD3_k127_7006217_3 pseudouridine synthase activity K06176 - 5.4.99.27 3.319e-203 644.0
HFD3_k127_7006217_4 2Fe-2S iron-sulfur cluster binding domain K00302 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004 456.0
HFD3_k127_7006217_5 Serine Threonine protein kinase K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008481 443.0
HFD3_k127_7006217_6 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 400.0
HFD3_k127_7006217_7 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 378.0
HFD3_k127_7006217_8 PFAM PHP domain K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 325.0
HFD3_k127_7006623_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 5.032e-224 717.0
HFD3_k127_7010935_0 carbon starvation protein CstA K06200 - - 0.000000000000000000000000000000000000000000000000000004847 201.0
HFD3_k127_7010935_1 - - - - 0.000000002204 68.0
HFD3_k127_7010935_2 - - - - 0.000004268 58.0
HFD3_k127_7012720_0 Thioesterase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000001716 225.0
HFD3_k127_7012720_1 lyase activity - - - 0.000000000000000000000000000000000000000000382 163.0
HFD3_k127_7012720_2 Protein of unknown function (DUF1501) - - - 0.000000002609 59.0
HFD3_k127_7012720_3 PFAM Rubrerythrin - - - 0.000007689 53.0
HFD3_k127_7012720_4 lyase activity - - - 0.0006341 44.0
HFD3_k127_7015395_0 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 322.0
HFD3_k127_7015395_1 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000001014 159.0
HFD3_k127_7015395_2 - - - - 0.000000000000000000000000000002122 120.0
HFD3_k127_703031_0 Heat shock 70 kDa protein - - - 1.249e-283 890.0
HFD3_k127_703031_1 Asparagine synthase K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 414.0
HFD3_k127_703031_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 339.0
HFD3_k127_703031_3 domain protein K21029,K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 318.0
HFD3_k127_703031_4 Catalyzes the synthesis of activated sulfate K00390,K00860 - 1.8.4.10,1.8.4.8,2.7.1.25 0.00000000000000000000000000000000000000000000000000000000000000005356 235.0
HFD3_k127_703031_5 Involved in molybdopterin and thiamine biosynthesis, family 2 - - - 0.000000000000000000000000000000000000000000000002416 186.0
HFD3_k127_703031_7 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000000000000000000000002964 143.0
HFD3_k127_703031_8 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000001411 91.0
HFD3_k127_7047034_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 4.233e-246 779.0
HFD3_k127_7047034_1 Alpha/beta hydrolase family K03928 - 3.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004192 278.0
HFD3_k127_7047034_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004709 258.0
HFD3_k127_7047034_3 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006486 242.0
HFD3_k127_7047034_4 PilZ domain - - - 0.0000000000003514 77.0
HFD3_k127_7048055_0 Domain of unknown function (DUF4175) - - - 4.137e-290 923.0
HFD3_k127_7048055_1 ATPase associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005218 543.0
HFD3_k127_7048055_2 Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 558.0
HFD3_k127_7048055_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007793 544.0
HFD3_k127_7048055_4 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 495.0
HFD3_k127_7048055_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 414.0
HFD3_k127_7048055_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 295.0
HFD3_k127_7048055_7 peptidase m48, ste24p - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003309 291.0
HFD3_k127_7048055_9 - - - - 0.00000000000000000000000000000001785 133.0
HFD3_k127_7048929_0 Peptidase S46 - - - 2.486e-275 867.0
HFD3_k127_7048929_1 Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 562.0
HFD3_k127_7048929_2 Domain of unknown function (DUF4382) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006902 312.0
HFD3_k127_7048929_3 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004597 273.0
HFD3_k127_7048929_4 PAP2 superfamily C-terminal - - - 0.000000000000000000000000000000000000000000001856 175.0
HFD3_k127_7050613_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0 1045.0
HFD3_k127_7050613_1 DNA polymerase III, delta' K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 526.0
HFD3_k127_7050613_2 Phosphoserine phosphatase K15781,K21830 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 2.3.1.51,3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 388.0
HFD3_k127_7050613_3 TatD family K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006218 381.0
HFD3_k127_7050613_4 Domain present in PSD-95, Dlg, and ZO-1/2. K08070 - 1.3.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 386.0
HFD3_k127_7050613_5 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000008122 251.0
HFD3_k127_7050613_6 PFAM DivIVA family protein K04074 - - 0.0000000000000000000000000000000000000000000000000000000007492 207.0
HFD3_k127_7050613_8 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000000000000000000000000000002709 167.0
HFD3_k127_7050613_9 Universal stress protein - - - 0.0000000000000000000000000005699 118.0
HFD3_k127_7062949_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 1.305e-209 676.0
HFD3_k127_7062949_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 469.0
HFD3_k127_7062949_2 PQQ enzyme repeat K17713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 345.0
HFD3_k127_7062949_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 298.0
HFD3_k127_7062949_4 protein trimerization K15368 - - 0.000000000000000000000000000000000000000000000000000001531 200.0
HFD3_k127_7062949_5 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000001675 150.0
HFD3_k127_7062949_7 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030312,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:0140096,GO:1901564 5.2.1.8 0.00000000000004821 72.0
HFD3_k127_7068143_0 AMP-binding enzyme C-terminal domain K12429,K18662 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051087 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004849 511.0
HFD3_k127_7068143_1 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 374.0
HFD3_k127_7068143_2 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 372.0
HFD3_k127_7068143_3 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005578 292.0
HFD3_k127_7068143_4 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.00000000000000000000000000000000000001507 147.0
HFD3_k127_7114627_0 Domain of unknown function (DUF4388) K12132 - 2.7.11.1 5.705e-206 664.0
HFD3_k127_7114627_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005859 541.0
HFD3_k127_7114627_2 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006334 467.0
HFD3_k127_7114627_3 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 421.0
HFD3_k127_7114627_4 Nucleotidyl transferase K00966,K16881 - 2.7.7.13,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 411.0
HFD3_k127_7114627_5 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 372.0
HFD3_k127_7114627_6 Protein serine threonine phosphatase K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005938 395.0
HFD3_k127_7114627_7 GAF domain-containing protein K08968 - 1.8.4.14 0.000000000000000000000000000000000000000000000001487 184.0
HFD3_k127_7114627_8 Nucleoside H+ symporter K05820 - - 0.0000000000000000000000000000000000000000000001921 171.0
HFD3_k127_7125460_0 PFAM Alcohol dehydrogenase zinc-binding domain protein K07119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 423.0
HFD3_k127_7125460_1 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 317.0
HFD3_k127_7125460_2 alpha/beta hydrolase fold - - - 0.000000000000000000000000003644 117.0
HFD3_k127_7125550_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 485.0
HFD3_k127_7125550_1 cell septum assembly - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 321.0
HFD3_k127_7128843_0 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 6.262e-304 951.0
HFD3_k127_7128843_1 Sigma-54 interaction domain - - - 2.306e-239 764.0
HFD3_k127_7128843_10 PFAM Hemerythrin HHE cation binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005254 249.0
HFD3_k127_7128843_11 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000000005847 201.0
HFD3_k127_7128843_12 CBS domain K04767,K07168,K07182 - - 0.00000000000000000000000000000000000000000000000000656 195.0
HFD3_k127_7128843_13 TIGRFAM Molybdopterin-guanine dinucleotide biosynthesis protein B K03753 - - 0.0000000000000000000000000000000000000000000000982 190.0
HFD3_k127_7128843_14 mttA/Hcf106 family K03116 - - 0.0000000000001209 74.0
HFD3_k127_7128843_15 DnaK suppressor protein - - - 0.0000000000007665 81.0
HFD3_k127_7128843_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006973 509.0
HFD3_k127_7128843_3 Protoglobin - GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005515,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0020037,GO:0023014,GO:0023052,GO:0035556,GO:0036094,GO:0036211,GO:0042802,GO:0042803,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046906,GO:0046983,GO:0048037,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0097159,GO:0140096,GO:1901363,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 494.0
HFD3_k127_7128843_4 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 479.0
HFD3_k127_7128843_5 Crp-like helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 386.0
HFD3_k127_7128843_7 Phospholipase D Active site motif K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 347.0
HFD3_k127_7128843_8 Alpha-amylase domain K01176 - 3.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 324.0
HFD3_k127_7128843_9 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 308.0
HFD3_k127_7137326_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1422.0
HFD3_k127_7137326_1 MazG nucleotide pyrophosphohydrolase domain K02499,K04765 - 3.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 406.0
HFD3_k127_7137326_3 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000000000001528 99.0
HFD3_k127_7137326_4 Membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.000000000005956 71.0
HFD3_k127_7140084_0 Protein of unknown function (DUF2867) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 290.0
HFD3_k127_7140084_1 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009731 260.0
HFD3_k127_7140084_2 Secretory protein of YscJ/FliF family K03222 - - 0.00000000000000000000000000000000000000000000000000000000000000000005956 238.0
HFD3_k127_7140084_3 PFAM peptidase M48 Ste24p - - - 0.00000000000000000000000000000000000000000000000000000002691 201.0
HFD3_k127_7140084_4 peptidylprolyl isomerase, FKBP-type K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000001209 194.0
HFD3_k127_7140084_5 4-Oxalocrotonate Tautomerase - - - 0.00000000000000000000000000000000000000000002883 166.0
HFD3_k127_7152883_0 TIGRFAM decaheme c-type cytochrome, OmcA MtrC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 470.0
HFD3_k127_7159308_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009472 549.0
HFD3_k127_7159308_1 Response regulator, receiver K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 422.0
HFD3_k127_716998_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0 1067.0
HFD3_k127_716998_1 DnaJ molecular chaperone homology domain - - - 0.00000000000000000000000000005251 131.0
HFD3_k127_7170085_0 thiosulfate sulfurtransferase activity K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 343.0
HFD3_k127_7170085_1 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000001154 203.0
HFD3_k127_7170085_2 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214 - 3.2.1.68 0.00000000000001087 75.0
HFD3_k127_7170085_3 - K07112 - - 0.00000000001193 77.0
HFD3_k127_7173339_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 9.033e-241 758.0
HFD3_k127_7173339_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 4.859e-238 777.0
HFD3_k127_7173339_10 Yqey-like protein K09117 - - 0.000000000001036 67.0
HFD3_k127_7173339_11 - - - - 0.000000000004456 70.0
HFD3_k127_7173339_2 PFAM AMP-dependent synthetase and ligase K12429,K18662 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051087 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008707 524.0
HFD3_k127_7173339_3 ABC-type branched-chain amino acid transport K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008362 511.0
HFD3_k127_7173339_4 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 385.0
HFD3_k127_7173339_5 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005213 381.0
HFD3_k127_7173339_6 C4-type zinc ribbon domain K07164 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009541 309.0
HFD3_k127_7173339_7 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008171 291.0
HFD3_k127_7173339_8 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004146 283.0
HFD3_k127_7173339_9 Ribonuclease H K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000001115 265.0
HFD3_k127_7192498_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.887e-289 918.0
HFD3_k127_7192498_1 Belongs to the RuBisCO large chain family K01601 - 4.1.1.39 3.649e-265 823.0
HFD3_k127_7192498_2 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006411 545.0
HFD3_k127_7192498_3 Phosphoribulokinase / Uridine kinase family K00855 - 2.7.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003592 481.0
HFD3_k127_7192498_4 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K01086,K03841 - 3.1.3.11,3.1.3.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006182 495.0
HFD3_k127_7192498_5 CbbX protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006632 434.0
HFD3_k127_7192498_6 Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.000000000000000000000000000000000000000000000000006326 194.0
HFD3_k127_7192498_7 LysR substrate binding domain K21703 - - 0.00002083 47.0
HFD3_k127_7211327_0 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 374.0
HFD3_k127_7211327_1 ABC transporter K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002774 353.0
HFD3_k127_7211327_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001218 260.0
HFD3_k127_7211327_3 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000000000000000002566 189.0
HFD3_k127_7215219_0 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 431.0
HFD3_k127_7215219_1 Glucose dehydrogenase C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 380.0
HFD3_k127_7215219_2 RarD protein K05786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 335.0
HFD3_k127_7215219_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000001053 144.0
HFD3_k127_7215219_5 - - - - 0.00000000005202 76.0
HFD3_k127_7215219_6 Major facilitator Superfamily - - - 0.00002646 56.0
HFD3_k127_7232145_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.0 1139.0
HFD3_k127_7232145_1 ABC transporter K06147,K06148 - - 1.987e-285 887.0
HFD3_k127_7232145_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009498 333.0
HFD3_k127_7232145_3 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008145 261.0
HFD3_k127_7232145_4 peptidyl-tyrosine sulfation - - - 0.0000000000000000001626 100.0
HFD3_k127_7233795_0 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000855 450.0
HFD3_k127_7233795_1 NAD(P)-binding Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 429.0
HFD3_k127_7233795_2 NAD(P)-binding Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 419.0
HFD3_k127_7233795_3 HAD-hyrolase-like K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000001974 264.0
HFD3_k127_7233795_4 DNA-templated transcription, initiation K03088,K11333 - 1.3.7.14,1.3.7.15 0.000000000000000000000000000000000000000000000001226 201.0
HFD3_k127_7233795_5 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.00000000000000000000000000000000000000000000002241 189.0
HFD3_k127_7233795_8 endonuclease activity K07451 - - 0.000182 49.0
HFD3_k127_7236719_0 Phosphofructokinase K00850,K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007007 576.0
HFD3_k127_7236719_1 Mitochondrial small ribosomal subunit Rsm22 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 558.0
HFD3_k127_7236719_10 hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000000001108 209.0
HFD3_k127_7236719_2 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 552.0
HFD3_k127_7236719_3 chromosome segregation K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006169 494.0
HFD3_k127_7236719_4 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 494.0
HFD3_k127_7236719_5 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 439.0
HFD3_k127_7236719_6 nitric oxide dioxygenase activity K00523,K15983 - 1.14.13.142,1.17.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 409.0
HFD3_k127_7236719_7 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 407.0
HFD3_k127_7236719_8 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 389.0
HFD3_k127_7236719_9 MgtC family K07507 - - 0.000000000000000000000000000000000000000000000000000000000000000000005082 263.0
HFD3_k127_7237661_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0 1465.0
HFD3_k127_7237661_1 nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 488.0
HFD3_k127_7237661_10 protein transport across the cell outer membrane K08084 - - 0.0009364 50.0
HFD3_k127_7237661_2 exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 372.0
HFD3_k127_7237661_3 Thioredoxin K03671 - - 0.0000000000000000000000000000000000000000000000000000000001449 215.0
HFD3_k127_7237661_4 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553,K14160 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000001749 210.0
HFD3_k127_7237661_5 Type IV Pilus-assembly protein W K02672 - - 0.0000000000000000006975 102.0
HFD3_k127_7237661_6 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.0000000000000000007872 89.0
HFD3_k127_7237661_7 Cupredoxin-like domain - - - 0.00000000000002006 78.0
HFD3_k127_7237661_9 TIGRFAM type IV pilus modification protein PilV K02671 - - 0.0006156 49.0
HFD3_k127_7248829_0 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 564.0
HFD3_k127_7252000_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848,K20906 - 5.4.99.2,5.4.99.64 1.439e-272 867.0
HFD3_k127_7252000_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 2.326e-237 741.0
HFD3_k127_7252000_2 GMC oxidoreductase K00108 - 1.1.99.1 1.141e-235 740.0
HFD3_k127_7252000_3 TIGRFAM LAO AO transport system ATPase K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 370.0
HFD3_k127_7252000_4 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000305 239.0
HFD3_k127_7252000_5 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000003767 235.0
HFD3_k127_7252000_6 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000008406 241.0
HFD3_k127_7252000_7 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000001323 224.0
HFD3_k127_7252000_8 COG2185 Methylmalonyl-CoA mutase, C-terminal domain subunit (cobalamin-binding) K01849,K20907 - 5.4.99.2,5.4.99.64 0.000000000000000000000000000000000000000000000000004999 209.0
HFD3_k127_7252000_9 regulatory protein GntR HTH - - - 0.0000000000000000000000000000000000000000000000005994 198.0
HFD3_k127_7264998_0 Pfam:Pyridox_oxidase K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 348.0
HFD3_k127_7264998_1 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003599 276.0
HFD3_k127_7264998_2 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003945 282.0
HFD3_k127_7264998_3 ADP binding - - - 0.00000000000000000000000000000000000000000000000000000000007921 231.0
HFD3_k127_7264998_4 cAMP biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000006438 218.0
HFD3_k127_7272915_0 Fungal trichothecene efflux pump (TRI12) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 593.0
HFD3_k127_7272915_1 Oligoendopeptidase f - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 302.0
HFD3_k127_7272915_2 Protein of unknown function (DUF2892) - - - 0.0000000000000000007642 90.0
HFD3_k127_7280652_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004747 546.0
HFD3_k127_7280652_1 aryl-alcohol dehydrogenase K19265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 551.0
HFD3_k127_7280652_2 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 513.0
HFD3_k127_7280652_3 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 409.0
HFD3_k127_7280652_4 ABC-type sugar transport system, permease component K17317 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 323.0
HFD3_k127_7280652_5 Transporter associated domain K03699 - - 0.00000000000000000000000000000000000000001048 156.0
HFD3_k127_7280652_6 - - - - 0.0000000000000000000001774 113.0
HFD3_k127_7280652_7 PilZ domain - - - 0.000000000002267 73.0
HFD3_k127_7295947_0 PFAM response regulator receiver K07713 - - 3.697e-209 698.0
HFD3_k127_7295947_1 HAMP domain K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008793 550.0
HFD3_k127_7295947_2 Cytochrome c3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006324 475.0
HFD3_k127_7295947_3 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 349.0
HFD3_k127_7295947_4 Peptidase family M54 K06974 - - 0.00000000000000000000000000000000000000000000000000000000353 204.0
HFD3_k127_7295947_5 Peptidase family M48 - - - 0.00005781 55.0
HFD3_k127_7307093_0 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005317 384.0
HFD3_k127_7307093_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 365.0
HFD3_k127_7307093_2 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 377.0
HFD3_k127_7307093_3 Transcriptional regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000007859 229.0
HFD3_k127_7307093_4 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000002061 168.0
HFD3_k127_7315034_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 3.361e-204 642.0
HFD3_k127_7315034_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007742 603.0
HFD3_k127_7315034_10 S-adenosylhomocysteine deaminase activity K12960 - 3.5.4.28,3.5.4.31 0.000000007245 63.0
HFD3_k127_7315034_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 378.0
HFD3_k127_7315034_3 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 339.0
HFD3_k127_7315034_4 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003684 330.0
HFD3_k127_7315034_5 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007515 338.0
HFD3_k127_7315034_6 Transcription factor zinc-finger K09981 - - 0.00000000000000000000000000000000000000000000000001267 184.0
HFD3_k127_7315034_7 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000000000000000000000000000000001506 140.0
HFD3_k127_7315034_9 - - - - 0.000000000000000003755 85.0
HFD3_k127_7316847_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 474.0
HFD3_k127_7316847_1 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 288.0
HFD3_k127_7316847_3 PilZ domain K02676 - - 0.00000000000000000000000000000000000000000000000001046 190.0
HFD3_k127_7316847_4 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000000000000002889 150.0
HFD3_k127_7327369_0 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 379.0
HFD3_k127_7327369_1 PFAM metal-dependent phosphohydrolase, HD sub domain K01524,K06950 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 338.0
HFD3_k127_7327369_2 Transport and Golgi organisation 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000654 248.0
HFD3_k127_7327369_3 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000000000000002408 222.0
HFD3_k127_7327369_4 Protein of unknown function (DUF971) K03593 - - 0.0000000000000000000000000000000000000000005319 163.0
HFD3_k127_7337663_0 Tetratricopeptide repeat - - - 0.0 1244.0
HFD3_k127_7337663_1 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 597.0
HFD3_k127_7341056_0 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 2.269e-202 640.0
HFD3_k127_7341056_1 Belongs to the LarC family K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 529.0
HFD3_k127_7341056_2 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 391.0
HFD3_k127_7341056_3 chemotaxis K03410 GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896,GO:0050918 - 0.000000000000000000000000000000000000000000000000000007026 213.0
HFD3_k127_7341056_4 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000007293 61.0
HFD3_k127_734757_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 3.572e-270 848.0
HFD3_k127_734757_1 PTS HPr component phosphorylation site K11189 - - 0.0000000000000000000000000000000966 125.0
HFD3_k127_7353766_0 Major Facilitator Superfamily - - - 2.533e-206 651.0
HFD3_k127_7353766_1 CBS domain containing protein K06189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 444.0
HFD3_k127_7353766_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000768 385.0
HFD3_k127_7353766_3 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 370.0
HFD3_k127_7353766_4 PFAM peptidase T2 asparaginase 2 K01444,K13051 - 3.4.19.5,3.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 328.0
HFD3_k127_7353766_5 hydrolase of the alpha beta superfamily K07018 - - 0.00000000000000000000000000000000000000000000003606 182.0
HFD3_k127_7353766_6 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000007266 125.0
HFD3_k127_7370417_0 benzoyl-CoA oxygenase K15512 - 1.14.13.208 3.247e-234 731.0
HFD3_k127_7370417_1 Enoyl-CoA hydratase/isomerase K15513 - 4.1.2.44 8.944e-233 734.0
HFD3_k127_7370417_2 Aldehyde dehydrogenase family K02618,K15514 - 1.2.1.77,1.2.1.91,3.3.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 587.0
HFD3_k127_7370417_3 Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003564 558.0
HFD3_k127_7370417_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009203 414.0
HFD3_k127_7370417_5 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006082 415.0
HFD3_k127_7370417_6 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 373.0
HFD3_k127_7370417_7 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 347.0
HFD3_k127_7370417_8 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 299.0
HFD3_k127_7370417_9 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000005666 169.0
HFD3_k127_7377842_0 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 319.0
HFD3_k127_7377842_1 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000003519 190.0
HFD3_k127_7377842_2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000005137 138.0
HFD3_k127_7377842_3 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000106 145.0
HFD3_k127_7377842_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000001308 76.0
HFD3_k127_7406831_0 Methyl-transferase K18912 - 1.14.99.50 1.368e-195 617.0
HFD3_k127_7406831_1 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009433 586.0
HFD3_k127_7406831_2 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 363.0
HFD3_k127_7406831_3 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001078 260.0
HFD3_k127_7406831_4 ribonucleoside-diphosphate reductase activity K07735 - - 0.00000000000000000000000000000000000000000000000000000000001248 215.0
HFD3_k127_7413459_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008391 537.0
HFD3_k127_7413459_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 467.0
HFD3_k127_7413459_10 - - - - 0.0000000001032 70.0
HFD3_k127_7413459_2 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 376.0
HFD3_k127_7413459_3 Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA K00556 - 2.1.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 328.0
HFD3_k127_7413459_4 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000001432 226.0
HFD3_k127_7413459_5 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000004744 188.0
HFD3_k127_7413459_6 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.0000000000000000000000000000001138 143.0
HFD3_k127_7413459_7 protein import - - - 0.0000000000000000000000000002157 124.0
HFD3_k127_7413459_8 thiolester hydrolase activity - - - 0.000000000000000000000000002681 126.0
HFD3_k127_7413459_9 - - - - 0.000000000000000000000003441 113.0
HFD3_k127_7415885_0 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 1.602e-202 634.0
HFD3_k127_7415885_1 PFAM FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008352 487.0
HFD3_k127_7415885_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000009196 87.0
HFD3_k127_7419024_0 Sigma-54 interaction domain K07713,K07714 - - 3.641e-210 665.0
HFD3_k127_7419024_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008698 539.0
HFD3_k127_7419024_2 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 455.0
HFD3_k127_7419024_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008461 268.0
HFD3_k127_7419024_4 - - - - 0.000000000000000000000000000000009726 131.0
HFD3_k127_7426520_0 Cysteine-rich domain K00113 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 565.0
HFD3_k127_7426520_1 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008663 251.0
HFD3_k127_7426520_2 - - - - 0.00000000000000000008195 99.0
HFD3_k127_7442841_0 ABC-type sugar transport system periplasmic component K17315 - - 1.727e-210 661.0
HFD3_k127_7442841_1 PFAM Binding-protein-dependent transport system inner membrane component K17316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 508.0
HFD3_k127_7442841_2 Belongs to the GHMP kinase family. GalK subfamily K00849,K00965 - 2.7.1.6,2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 492.0
HFD3_k127_7442841_3 ROK family K00847 - 2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 409.0
HFD3_k127_7442841_4 ABC-type sugar transport system, permease component K17317 - - 0.00000000000000001522 99.0
HFD3_k127_7463373_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 574.0
HFD3_k127_7463373_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 499.0
HFD3_k127_7463373_2 Outer membrane efflux protein K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 381.0
HFD3_k127_7463373_3 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 333.0
HFD3_k127_7463373_4 Periplasmic protein TonB links inner and outer membranes - - - 0.00000000000000000000000000000000000000000002175 168.0
HFD3_k127_7477249_0 PrkA serine protein kinase C-terminal domain - - - 0.0 1081.0
HFD3_k127_7477249_1 Heat shock 70 kDa protein K04043 - - 2.167e-260 848.0
HFD3_k127_7480036_0 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 519.0
HFD3_k127_7480036_1 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005242 356.0
HFD3_k127_7480036_2 3-hydroxyacyl-coa dehydrogenase K07516 - 1.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005217 304.0
HFD3_k127_7480615_0 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 470.0
HFD3_k127_7480615_1 endonuclease activity K07451 - - 0.0000000000000000000000000000000000000000000000000005754 188.0
HFD3_k127_7480615_2 TonB C terminal K03832 - - 0.0000002443 58.0
HFD3_k127_7484227_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 2.521e-218 692.0
HFD3_k127_7484227_1 Uncharacterised MFS-type transporter YbfB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007852 448.0
HFD3_k127_7484227_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001233 256.0
HFD3_k127_7484227_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.00000000000000000000000000000002458 128.0
HFD3_k127_7504474_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004326 449.0
HFD3_k127_7504474_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000004479 267.0
HFD3_k127_7504474_2 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.000000000000000001344 89.0
HFD3_k127_7504474_3 Recombinase zinc beta ribbon domain K06400 - - 0.00000007658 55.0
HFD3_k127_7510196_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008834 435.0
HFD3_k127_7510196_1 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 366.0
HFD3_k127_7510196_2 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000551 247.0
HFD3_k127_7510196_3 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000000694 102.0
HFD3_k127_7510196_4 - - - - 0.0000009142 56.0
HFD3_k127_7535205_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 2.064e-306 952.0
HFD3_k127_7535205_1 Carboxyl transferase domain - - - 2.721e-272 843.0
HFD3_k127_7535205_2 acyl-coa dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 595.0
HFD3_k127_7535205_4 HMGL-like K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 465.0
HFD3_k127_7535205_5 ArgK protein K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 393.0
HFD3_k127_7535205_6 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 352.0
HFD3_k127_7535205_7 methyltransferase activity K13613,K15677 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 310.0
HFD3_k127_7535205_8 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000798 240.0
HFD3_k127_7540225_0 ATP-binding region ATPase domain protein K03407,K13490 - 2.7.13.3 4.503e-315 1000.0
HFD3_k127_7540225_1 Methyl-accepting chemotaxis protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 563.0
HFD3_k127_7540225_10 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000007135 198.0
HFD3_k127_7540225_11 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896 3.5.1.44 0.00000000000000000000000000000000000000000000000004791 195.0
HFD3_k127_7540225_2 Chemotaxis protein histidine kinase and related kinases K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009309 531.0
HFD3_k127_7540225_3 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007243 433.0
HFD3_k127_7540225_4 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008959 404.0
HFD3_k127_7540225_5 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008201 357.0
HFD3_k127_7540225_6 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 341.0
HFD3_k127_7540225_7 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000000000000000000000000000000000003922 232.0
HFD3_k127_7540225_8 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000000000000000000000000000001079 216.0
HFD3_k127_7540225_9 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000002472 206.0
HFD3_k127_754119_0 Glutamate synthase K00266 - 1.4.1.13,1.4.1.14 9.171e-253 809.0
HFD3_k127_754119_1 Glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 1.042e-223 699.0
HFD3_k127_754119_2 energy transducer activity K03832 - - 0.00000000000000000000000000000000000000000000000000000326 205.0
HFD3_k127_754119_4 - - - - 0.00000000000000007291 82.0
HFD3_k127_7541515_0 MoeA C-terminal region (domain IV) K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 498.0
HFD3_k127_7541515_1 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005289 307.0
HFD3_k127_7541515_2 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000000000000000000000008299 198.0
HFD3_k127_7541515_3 sequence-specific DNA binding - - - 0.0000000000000000000000000001001 115.0
HFD3_k127_7557973_0 type IV pilus secretin PilQ K02666 - - 2.616e-280 884.0
HFD3_k127_7557973_1 Pilus assembly protein, PilP K02665 - - 0.0000000000000000000000000000000000000000000000000000001152 198.0
HFD3_k127_7562326_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1127.0
HFD3_k127_7562326_1 endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000006043 119.0
HFD3_k127_7562326_2 histone H2A K63-linked ubiquitination - - - 0.000000000000000000008631 93.0
HFD3_k127_7576945_0 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 344.0
HFD3_k127_7576945_1 Transcription factor zinc-finger K09981 - - 0.0000000000000000000000000000000000009372 143.0
HFD3_k127_7576945_2 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.0000000000000000000005815 109.0
HFD3_k127_7576945_3 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298 - 1.10.3.10,1.9.3.1 0.000000000000000000001503 94.0
HFD3_k127_7576945_4 - - - - 0.00001391 55.0
HFD3_k127_757754_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001832 283.0
HFD3_k127_757754_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000006392 167.0
HFD3_k127_7579052_0 PFAM AMP-dependent synthetase and ligase - - - 0.0 1983.0
HFD3_k127_7579052_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 5.286e-197 624.0
HFD3_k127_7579052_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01655 - 2.3.3.14 1.471e-195 622.0
HFD3_k127_7579052_3 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K15830 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 461.0
HFD3_k127_7579052_4 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter MnhD K12141 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 397.0
HFD3_k127_7579052_5 PFAM NADH ubiquinone oxidoreductase, 20 - - - 0.00000000000000000000000000000000000000000000000000000000000000001113 241.0
HFD3_k127_7579052_6 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000003291 232.0
HFD3_k127_7579052_7 hydrogenase 4 membrane K12140 - - 0.00000000000000000000000000001155 135.0
HFD3_k127_7579052_8 Proton-conducting membrane transporter - - - 0.0000000000000000005292 93.0
HFD3_k127_7579052_9 indolepyruvate ferredoxin oxidoreductase activity K00179,K08941 - 1.2.7.8 0.0000003572 56.0
HFD3_k127_758473_0 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 394.0
HFD3_k127_758473_1 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000000000000000000000000000000000000001507 235.0
HFD3_k127_758473_2 HAD-hyrolase-like K06019 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000001858 230.0
HFD3_k127_758473_3 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000000000000000000002687 211.0
HFD3_k127_758473_4 NUDIX domain - - - 0.00000000000000000000000000000000000000000000004277 195.0
HFD3_k127_758473_5 Putative inner membrane exporter, YdcZ K09936 - - 0.000000000000000000000000000000000000000000001004 179.0
HFD3_k127_758473_6 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000005503 124.0
HFD3_k127_7597792_0 Belongs to the FtsK SpoIIIE SftA family K03466 - - 0.0 1082.0
HFD3_k127_7597792_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000004976 182.0
HFD3_k127_7597792_4 zinc-ribbon domain - - - 0.000000000000000000000000002159 116.0
HFD3_k127_7614564_0 CBS domain containing protein K07182 - - 9.566e-248 780.0
HFD3_k127_7614564_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 4.076e-239 745.0
HFD3_k127_7614564_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 5.594e-206 653.0
HFD3_k127_7614564_3 EXOIII K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000002307 254.0
HFD3_k127_7614564_4 Domain of unknown function (DUF4212) - - - 0.000000000000000000000000000000000000004248 148.0
HFD3_k127_7620641_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 2.334e-227 732.0
HFD3_k127_7620641_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 581.0
HFD3_k127_7623869_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 568.0
HFD3_k127_7623869_1 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 326.0
HFD3_k127_7623869_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004746 296.0
HFD3_k127_7623869_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003157 268.0
HFD3_k127_7623869_4 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000136 262.0
HFD3_k127_7623869_5 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008969 260.0
HFD3_k127_7623869_6 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000000000000000000000000000000000000000000000000002593 205.0
HFD3_k127_7623869_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000608 53.0
HFD3_k127_7627746_0 alcohol dehydrogenase K00001 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 484.0
HFD3_k127_7627746_1 S-acyltransferase activity K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005274 342.0
HFD3_k127_7627746_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 314.0
HFD3_k127_7627746_3 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 296.0
HFD3_k127_7627746_4 ATPases associated with a variety of cellular activities K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009874 288.0
HFD3_k127_7627746_5 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007134 255.0
HFD3_k127_7627746_6 PFAM cytochrome C oxidase mono-heme subunit FixO K00405 - - 0.00000000000000000000000000000000000000000000002819 181.0
HFD3_k127_763620_0 response regulator K02481,K07713 - - 1.368e-271 841.0
HFD3_k127_763620_1 Nucleic acid binding OB-fold tRNA helicase-type K03698 - - 1.612e-200 636.0
HFD3_k127_763620_2 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 314.0
HFD3_k127_763620_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000001218 175.0
HFD3_k127_763620_4 zinc ion binding K06204 - - 0.000000000000000000000000000001239 124.0
HFD3_k127_763620_5 IMP dehydrogenase activity K06041,K11527 - 2.7.13.3,5.3.1.13 0.0000000000000000000000001083 113.0
HFD3_k127_7639888_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K00179 - 1.2.7.8 0.0 1374.0
HFD3_k127_7639888_1 xanthine dehydrogenase activity K04108 - 1.3.7.9 4.257e-258 822.0
HFD3_k127_7639888_10 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000001006 206.0
HFD3_k127_7639888_11 PFAM regulatory protein TetR K09017 - - 0.000000000000000000000006155 111.0
HFD3_k127_7639888_2 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 649.0
HFD3_k127_7639888_3 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 564.0
HFD3_k127_7639888_4 Amino acid amide ABC transporter substrate-binding protein, HAAT family K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 419.0
HFD3_k127_7639888_5 Enoyl-CoA hydratase isomerase K16427 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016701,GO:0016702,GO:0042802,GO:0051213,GO:0055114 1.13.11.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 398.0
HFD3_k127_7639888_6 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 361.0
HFD3_k127_7639888_7 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008322 304.0
HFD3_k127_7639888_8 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 301.0
HFD3_k127_7639888_9 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 304.0
HFD3_k127_7667147_0 Elongation factor G, domain IV K02355 - - 0.0 1065.0
HFD3_k127_7667147_1 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 533.0
HFD3_k127_7667147_10 transcription regulator, contains HTH domain (MarR family) - - - 0.0000000000000000000000000000000000000000000000000009913 189.0
HFD3_k127_7667147_11 GyrI-like small molecule binding domain - - - 0.0000000000000001163 84.0
HFD3_k127_7667147_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 391.0
HFD3_k127_7667147_3 Belongs to the D-glutamate cyclase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 347.0
HFD3_k127_7667147_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 371.0
HFD3_k127_7667147_5 Belongs to the UPF0271 (lamB) family K07160 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 286.0
HFD3_k127_7667147_6 TIGRFAM urea amidolyase related protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006685 304.0
HFD3_k127_7667147_7 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003561 279.0
HFD3_k127_7667147_8 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000004844 235.0
HFD3_k127_7667147_9 Allophanate hydrolase subunit 1 - - - 0.000000000000000000000000000000000000000000000000000000001784 216.0
HFD3_k127_7668319_0 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.000000009857 69.0
HFD3_k127_7668319_1 lyase activity - - - 0.0003279 53.0
HFD3_k127_7668431_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 507.0
HFD3_k127_7668431_1 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007433 381.0
HFD3_k127_7668431_2 Metallophosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 302.0
HFD3_k127_7668431_3 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007671 313.0
HFD3_k127_7668431_4 Glyoxalase-like domain K07032 - - 0.0000000000000000000000000000000000000000000000000000000001065 207.0
HFD3_k127_7668431_5 PFAM Cytochrome c, class I - - - 0.00000000000000000000000000000000000000000000000003512 190.0
HFD3_k127_7668431_7 YCII-related domain - - - 0.00000000000000000000000000172 121.0
HFD3_k127_7668431_8 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.0000000000000003588 93.0
HFD3_k127_7668431_9 AntiSigma factor - - - 0.0000000000006774 73.0
HFD3_k127_7670433_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 1.503e-228 723.0
HFD3_k127_7670433_1 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006558 545.0
HFD3_k127_7670433_2 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000002222 265.0
HFD3_k127_7670496_0 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 607.0
HFD3_k127_7670496_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 462.0
HFD3_k127_7670496_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 347.0
HFD3_k127_7670496_3 - - - - 0.0000000000000000000000000000000000000000000000000001285 211.0
HFD3_k127_7673266_0 Protein of unknown function (DUF423) - - - 0.000000000000000000000000000000000000000000001413 180.0
HFD3_k127_7673266_1 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000000000000000003742 158.0
HFD3_k127_7673266_2 Proton-dependent permease that transports di- and tripeptides K03305 - - 0.000000001364 62.0
HFD3_k127_7676554_0 Glycosyl hydrolase 36 superfamily, catalytic domain K00702,K13688 - 2.4.1.20 0.0 1774.0
HFD3_k127_7678971_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 409.0
HFD3_k127_7680773_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 360.0
HFD3_k127_7680773_1 - K06198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004808 340.0
HFD3_k127_7680773_2 peroxiredoxin activity K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.0000000000000000000000000000000000000265 145.0
HFD3_k127_7680773_3 PFAM AhpC TSA family K03564 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.11.1.15 0.000000000004423 69.0
HFD3_k127_7684987_0 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003895 417.0
HFD3_k127_7691347_0 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 581.0
HFD3_k127_7691347_1 amine dehydrogenase activity - - - 0.0000000000007006 83.0
HFD3_k127_7692863_0 repeat protein - - - 1.752e-259 829.0
HFD3_k127_7699186_0 DEAD DEAH box helicase - - - 0.0 1333.0
HFD3_k127_7699186_1 Regulator of chromosome condensation (RCC1) repeat - - - 1.336e-208 669.0
HFD3_k127_7699186_2 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 326.0
HFD3_k127_7699186_3 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000942 316.0
HFD3_k127_7699186_4 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009509 291.0
HFD3_k127_7699186_5 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000000000000000000001125 207.0
HFD3_k127_7699186_6 PFAM Class I peptide chain release factor K15034 - - 0.000000000000000000000000000000000000009365 153.0
HFD3_k127_7699186_8 MacB-like periplasmic core domain K09808 - - 0.0000001246 53.0
HFD3_k127_7699186_9 Protein of unknown function, DUF488 - - - 0.0003791 49.0
HFD3_k127_7700965_0 heat shock protein 70 K04043 - - 1.173e-307 970.0
HFD3_k127_7700965_1 acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 524.0
HFD3_k127_7700965_2 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005478 416.0
HFD3_k127_7700965_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 399.0
HFD3_k127_7700965_4 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 348.0
HFD3_k127_7700965_5 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000002291 102.0
HFD3_k127_7712027_0 DUF1704 - - - 2.171e-200 664.0
HFD3_k127_7712027_1 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 541.0
HFD3_k127_7712027_2 PFAM peptidase M48 Ste24p - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 476.0
HFD3_k127_7712027_3 PFAM LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 311.0
HFD3_k127_7712027_4 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000000000000000000000000000000001736 166.0
HFD3_k127_7721560_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840,K15778 - 5.4.2.2,5.4.2.8 1.129e-224 724.0
HFD3_k127_7721560_1 Mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006726 534.0
HFD3_k127_7721560_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 394.0
HFD3_k127_7721560_3 PFAM ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009639 371.0
HFD3_k127_7721560_4 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000001258 255.0
HFD3_k127_7721560_5 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000000000004488 224.0
HFD3_k127_7721560_6 energy transducer activity K03832 - - 0.00000000000000000000000000000000000000000000000000000001564 205.0
HFD3_k127_7725899_0 Heat shock protein DnaJ domain protein K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 407.0
HFD3_k127_7725899_1 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 344.0
HFD3_k127_7725899_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.00000000000000002698 82.0
HFD3_k127_773053_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.038e-238 741.0
HFD3_k127_773053_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 1.021e-215 691.0
HFD3_k127_773053_3 Type IV minor pilin ComP, DNA uptake sequence receptor - - - 0.000282 54.0
HFD3_k127_7740822_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 8.926e-272 846.0
HFD3_k127_7740822_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 610.0
HFD3_k127_7740822_2 Major facilitator superfamily MFS_1 K02445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 617.0
HFD3_k127_7740822_3 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00162,K11381 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004192 503.0
HFD3_k127_7740822_4 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00161,K00162,K11381,K21416 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007675 436.0
HFD3_k127_7740822_5 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005235 256.0
HFD3_k127_7740822_6 phosphoribosyltransferase K07100 - - 0.000000000000000000000000000000000000000000000000000000000006342 234.0
HFD3_k127_7740822_7 YhhN family - - - 0.000000000000000000000000000000000000000000000000001513 190.0
HFD3_k127_7740822_8 cystathionine gamma-synthase activity K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.0000000000000000000000000003569 115.0
HFD3_k127_7740822_9 e3 binding domain K00627 - 2.3.1.12 0.0000000000000000000000000003984 121.0
HFD3_k127_77476_0 Belongs to the thiolase family K00626 - 2.3.1.9 6.987e-197 621.0
HFD3_k127_77476_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000985 570.0
HFD3_k127_77476_10 - - - - 0.00000000000000000000000000000000000000002334 170.0
HFD3_k127_77476_11 - - - - 0.000000000000002826 86.0
HFD3_k127_77476_2 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004658 528.0
HFD3_k127_77476_3 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 419.0
HFD3_k127_77476_4 Asparaginase K13051 - 3.4.19.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 412.0
HFD3_k127_77476_5 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01028 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 364.0
HFD3_k127_77476_6 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 371.0
HFD3_k127_77476_7 Coenzyme A transferase K01029 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 329.0
HFD3_k127_77476_8 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 332.0
HFD3_k127_77476_9 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000000000003549 229.0
HFD3_k127_77547_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 3.844e-255 813.0
HFD3_k127_77547_1 PFAM ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 352.0
HFD3_k127_782878_0 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 586.0
HFD3_k127_782878_1 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 578.0
HFD3_k127_782878_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009327 529.0
HFD3_k127_782878_3 HD domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005433 489.0
HFD3_k127_782878_4 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 466.0
HFD3_k127_782878_5 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007064 377.0
HFD3_k127_782878_6 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009464 374.0
HFD3_k127_782878_7 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000000000000000000003096 207.0
HFD3_k127_782878_8 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000006134 162.0
HFD3_k127_794012_0 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 463.0
HFD3_k127_794012_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K15893 - 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004577 454.0
HFD3_k127_794012_2 PFAM PHP domain protein K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000000000000000000000000003187 250.0
HFD3_k127_794012_3 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.000000000000000000000000000000000000000000000002955 180.0
HFD3_k127_794012_4 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000000000000001291 95.0
HFD3_k127_798923_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1315.0
HFD3_k127_798923_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005144 418.0
HFD3_k127_798923_2 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000552 271.0
HFD3_k127_805603_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 1.033e-276 854.0
HFD3_k127_805603_1 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005747 566.0
HFD3_k127_8060_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003837 454.0
HFD3_k127_8060_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008773 276.0
HFD3_k127_8060_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000004654 155.0
HFD3_k127_813627_0 PrkA AAA domain K07180 - - 2.272e-227 719.0
HFD3_k127_813627_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000002404 236.0
HFD3_k127_814824_0 Belongs to the N(4) N(6)-methyltransferase family K00571 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 491.0
HFD3_k127_814824_1 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 459.0
HFD3_k127_814824_10 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000006189 131.0
HFD3_k127_814824_11 GDP-mannose mannosyl hydrolase activity K01515,K03574 - 3.6.1.13,3.6.1.55 0.0000000000000000000000003721 106.0
HFD3_k127_814824_12 Redoxin K03564 - 1.11.1.15 0.0000000000000000000001248 97.0
HFD3_k127_814824_2 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 387.0
HFD3_k127_814824_3 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004823 401.0
HFD3_k127_814824_4 CarD-like/TRCF domain K07736 GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001862 303.0
HFD3_k127_814824_5 metallopeptidase activity K06974 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002515 274.0
HFD3_k127_814824_8 PFAM thioesterase superfamily K02614 - - 0.000000000000000000000000000000000000000000000000000004069 200.0
HFD3_k127_814824_9 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000001775 134.0
HFD3_k127_826401_0 Belongs to the thiolase family K07508 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005519 551.0
HFD3_k127_826401_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006587 341.0
HFD3_k127_826401_2 domain, Protein - - - 0.00000000000000000000000000000000000000000009652 163.0
HFD3_k127_826401_3 Eukaryotic integral membrane protein (DUF1751) - - - 0.000000000000000000000000000005787 128.0
HFD3_k127_826401_5 - - - - 0.000000001274 68.0
HFD3_k127_826401_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03117 - - 0.0002776 49.0
HFD3_k127_862633_0 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 499.0
HFD3_k127_862633_1 Protein of unknown function (DUF507) K09804 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 311.0
HFD3_k127_863418_0 tRNA synthetases class II (D, K and N) K04568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009777 456.0
HFD3_k127_863418_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001345 272.0
HFD3_k127_86603_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 1.372e-254 798.0
HFD3_k127_86603_1 Binding-protein-dependent transport system inner membrane component K02042 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000451 543.0
HFD3_k127_86603_2 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 456.0
HFD3_k127_86603_3 Bacterial extracellular solute-binding proteins, family 3 K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 419.0
HFD3_k127_86603_4 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001779 265.0
HFD3_k127_873998_0 Prephenate dehydratase K04518,K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007123 398.0
HFD3_k127_873998_1 histidine kinase HAMP region domain protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000001511 214.0
HFD3_k127_88154_0 SpoVR like protein K06415 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008738 547.0
HFD3_k127_88154_1 unusual protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000004875 252.0
HFD3_k127_88154_2 spore germination - - - 0.0000000000000000000000000000000000000000000000000000004497 199.0
HFD3_k127_932276_0 Histidine kinase K07710,K10125 - 2.7.13.3 1.952e-202 642.0
HFD3_k127_932276_1 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 7.63e-202 662.0
HFD3_k127_932276_2 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007249 359.0
HFD3_k127_932276_3 Belongs to the helicase family. UvrD subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 341.0
HFD3_k127_932276_4 denitrification pathway - - - 0.00001248 47.0
HFD3_k127_941711_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 3.666e-319 1024.0
HFD3_k127_941711_1 Belongs to the HypD family K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 548.0
HFD3_k127_941711_2 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008378 519.0
HFD3_k127_941711_3 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 410.0
HFD3_k127_941711_4 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000000000000000006561 145.0
HFD3_k127_941711_5 carbon dioxide binding K04653,K04654 - - 0.000000000000000000000000000000008331 148.0
HFD3_k127_941711_6 Vitamin K epoxide reductase family - - - 0.0000000000000000000000000000003557 139.0
HFD3_k127_965927_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1038.0
HFD3_k127_965927_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 8.685e-282 875.0
HFD3_k127_965927_10 PFAM YdjC family protein K03478 - 3.5.1.105 0.00000000000000000000000000000000000007589 147.0
HFD3_k127_965927_11 Bifunctional nuclease K08999 - - 0.000000000000000000001066 111.0
HFD3_k127_965927_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 7.598e-211 686.0
HFD3_k127_965927_3 Belongs to the CarA family K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009603 627.0
HFD3_k127_965927_4 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 519.0
HFD3_k127_965927_5 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009457 456.0
HFD3_k127_965927_6 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 377.0
HFD3_k127_965927_7 - K07039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009412 273.0
HFD3_k127_965927_8 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000006608 246.0
HFD3_k127_988114_0 CoA-substrate-specific enzyme activase - - - 0.0 1377.0