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Overview

ID MAG01686
Name HFD3_bin.28
Sample SMP0045
Taxonomy
Kingdom Bacteria
Phylum Actinomycetota
Class Acidimicrobiia
Order Acidimicrobiales
Family Ilumatobacteraceae
Genus JAENVT01
Species
Assembly information
Completeness (%) 83.86
Contamination (%) 1.8
GC content (%) 67.0
N50 (bp) 35,391
Genome size (bp) 4,189,216

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3760

Gene name Description KEGG GOs EC E-value Score Sequence
HFD3_k127_10309_0 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 561.0
HFD3_k127_10309_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 507.0
HFD3_k127_10309_10 dithiol-disulfide isomerase involved in polyketide biosynthesis - - - 0.0000000000000000000000000000000000000000001111 176.0
HFD3_k127_10309_11 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000001284 172.0
HFD3_k127_10309_12 Subtilase family - - - 0.000000000000000000000000000000000001224 156.0
HFD3_k127_10309_13 PFAM Phosphoglycerate mutase K08296 - - 0.000000000000000000000000000000002615 135.0
HFD3_k127_10309_14 - - - - 0.00000000000000000000000006066 116.0
HFD3_k127_10309_15 flavoprotein K19784 - - 0.00000000000000000000000006133 113.0
HFD3_k127_10309_16 - - - - 0.000000000000000000000003204 112.0
HFD3_k127_10309_17 Copper/zinc superoxide dismutase (SODC) K04565 - 1.15.1.1 0.000000000000000000000952 102.0
HFD3_k127_10309_18 - - - - 0.00000000000000000002274 101.0
HFD3_k127_10309_19 - - - - 0.0000000000000001181 93.0
HFD3_k127_10309_2 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 508.0
HFD3_k127_10309_20 Glutathione-dependent formaldehyde-activating - - - 0.000000000000007071 76.0
HFD3_k127_10309_21 - - - - 0.00000000000006263 83.0
HFD3_k127_10309_22 Belongs to the ompA family K20276 - - 0.0000000000003101 81.0
HFD3_k127_10309_23 Dodecin K09165 - - 0.000001053 54.0
HFD3_k127_10309_24 ADP-ribosylglycohydrolase K05521 - 3.2.2.24 0.0000598 46.0
HFD3_k127_10309_3 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 414.0
HFD3_k127_10309_4 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 343.0
HFD3_k127_10309_5 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000421 292.0
HFD3_k127_10309_6 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000006421 233.0
HFD3_k127_10309_7 ABC transporter K15555 - - 0.0000000000000000000000000000000000000000000000000000000000000001659 229.0
HFD3_k127_10309_8 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000005179 203.0
HFD3_k127_10309_9 Fibronectin type 3 domain - - - 0.000000000000000000000000000000000000000000000000006255 200.0
HFD3_k127_1038299_0 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 9.462e-233 727.0
HFD3_k127_1038299_1 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 390.0
HFD3_k127_1038299_2 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 337.0
HFD3_k127_1038299_3 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008023 251.0
HFD3_k127_1038299_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000001084 188.0
HFD3_k127_1038299_5 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000001731 122.0
HFD3_k127_1047767_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 3.616e-268 838.0
HFD3_k127_1047767_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 2.599e-221 694.0
HFD3_k127_1047767_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009699 424.0
HFD3_k127_1047767_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004565 259.0
HFD3_k127_1047767_4 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000009149 152.0
HFD3_k127_1047767_5 ATP synthesis coupled proton transport K02109 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0016020,GO:0016469,GO:0032991,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 - 0.0000000000000000000000000000000005027 137.0
HFD3_k127_1053582_0 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 9.214e-222 696.0
HFD3_k127_1053582_1 Cys/Met metabolism PLP-dependent enzyme K01739 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 502.0
HFD3_k127_1053582_2 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000001751 222.0
HFD3_k127_1053582_3 spore germination - - - 0.00000000000000000000000000000000000000001357 164.0
HFD3_k127_1053582_4 - - - - 0.00000000000000000000000000000008613 130.0
HFD3_k127_1053582_5 Multicopper oxidase - - - 0.00000000001254 71.0
HFD3_k127_1055975_0 Dehydrogenase E1 component K11381 - 1.2.4.4 5.543e-267 839.0
HFD3_k127_1055975_1 Rieske 2Fe-2S K00479 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 301.0
HFD3_k127_1055975_2 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001531 253.0
HFD3_k127_1055975_3 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.0000000000000000000000000000000000000000000000149 181.0
HFD3_k127_1055975_4 - - - - 0.000000000000000000000000000000000000000000003672 179.0
HFD3_k127_1055975_5 (GGDEF) domain K21023 - 2.7.7.65 0.000000000000000000000000000000000000002852 166.0
HFD3_k127_1055975_6 - - - - 0.0000000000000007143 85.0
HFD3_k127_1056699_0 Adenylyl cyclase class-3 4 guanylyl cyclase - - - 9.013e-256 842.0
HFD3_k127_1056699_1 PFAM glycosyl transferase family 39 - - - 1.206e-224 743.0
HFD3_k127_1056699_10 Aldolase/RraA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001535 248.0
HFD3_k127_1056699_11 Oxidoreductase family, NAD-binding Rossmann fold K00010 - 1.1.1.18,1.1.1.369 0.0000000000000000000000000000000000000000000002812 181.0
HFD3_k127_1056699_12 C-terminal domain of 1-Cys peroxiredoxin - - - 0.0000000000000000000000000000000000000000003504 158.0
HFD3_k127_1056699_13 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000368 183.0
HFD3_k127_1056699_14 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000001059 160.0
HFD3_k127_1056699_15 protein conserved in bacteria - - - 0.00000000000000000000000000000000001031 142.0
HFD3_k127_1056699_16 - - - - 0.00000000000000000000000000000004912 129.0
HFD3_k127_1056699_17 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000001062 127.0
HFD3_k127_1056699_18 Capsule synthesis protein K07282 - - 0.000000000000000001895 99.0
HFD3_k127_1056699_19 - - - - 0.00008835 48.0
HFD3_k127_1056699_2 GtrA-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 507.0
HFD3_k127_1056699_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009627 504.0
HFD3_k127_1056699_4 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007013 379.0
HFD3_k127_1056699_5 Peptidoglycan-binding domain 1 protein K01227,K01448,K03791,K13277,K17733 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016787,GO:0017171,GO:0018104,GO:0019538,GO:0030203,GO:0030312,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044464,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 3.2.1.96,3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 340.0
HFD3_k127_1056699_6 Glycosylase K05522 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 334.0
HFD3_k127_1056699_7 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 304.0
HFD3_k127_1056699_8 response to antibiotic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 315.0
HFD3_k127_1056699_9 ADP-ribose pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008977 270.0
HFD3_k127_1085197_0 Zinc-binding dehydrogenase K17829 - 1.3.1.86 1.652e-210 661.0
HFD3_k127_1085197_1 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 592.0
HFD3_k127_1085197_10 Prokaryotic N-terminal methylation motif - - - 0.0000000000006346 75.0
HFD3_k127_1085197_2 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 552.0
HFD3_k127_1085197_3 Type II secretion system (T2SS), protein F K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 510.0
HFD3_k127_1085197_4 Protein of unknown function (DUF429) K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 289.0
HFD3_k127_1085197_5 Type IV leader peptidase family K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000007957 256.0
HFD3_k127_1085197_6 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000001025 235.0
HFD3_k127_1085197_7 Glyoxalase-like domain K05606 - 5.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000002606 235.0
HFD3_k127_1085197_8 Glycosyl hydrolases family 18 - - - 0.00000000000000000000000000000000000000000000001231 186.0
HFD3_k127_1085197_9 - - - - 0.0000000000000000000000000000000000000003809 165.0
HFD3_k127_1114954_0 Seryl-tRNA synthetase N-terminal domain K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005009 578.0
HFD3_k127_1114954_1 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0010181,GO:0016491,GO:0016614,GO:0016899,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032553,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0042803,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000002002 267.0
HFD3_k127_1114954_2 Replication protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000002711 248.0
HFD3_k127_1114954_3 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000001763 253.0
HFD3_k127_1114954_4 Cytochrome c biogenesis protein transmembrane region - - - 0.00000000000000000000000000000000000000000000000000003598 207.0
HFD3_k127_1114954_5 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18958 GO:0001101,GO:0008150,GO:0010033,GO:0033993,GO:0042221,GO:0046677,GO:0050896,GO:0070542,GO:1901700 - 0.0000000000000000000000000000000000002204 145.0
HFD3_k127_1114954_6 Redoxin - - - 0.0000000000000000000000000000000000005563 147.0
HFD3_k127_1122473_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1100.0
HFD3_k127_1122473_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 9.76e-307 963.0
HFD3_k127_1122473_10 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 421.0
HFD3_k127_1122473_11 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 380.0
HFD3_k127_1122473_12 Amidinotransferase K01482 - 3.5.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008817 364.0
HFD3_k127_1122473_13 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 362.0
HFD3_k127_1122473_14 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 329.0
HFD3_k127_1122473_15 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003491 285.0
HFD3_k127_1122473_16 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000008475 235.0
HFD3_k127_1122473_17 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000008521 246.0
HFD3_k127_1122473_18 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000613 229.0
HFD3_k127_1122473_19 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000001107 215.0
HFD3_k127_1122473_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 1.226e-254 796.0
HFD3_k127_1122473_20 Protein of unknown function (DUF3048) C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000001129 229.0
HFD3_k127_1122473_21 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000000000000000002402 208.0
HFD3_k127_1122473_22 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.00000000000000000000000000000000000000000000000002504 194.0
HFD3_k127_1122473_23 nUDIX hydrolase K08311 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010468,GO:0010604,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019219,GO:0019222,GO:0019439,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0033554,GO:0034353,GO:0034641,GO:0034655,GO:0043167,GO:0043169,GO:0043170,GO:0043487,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0045935,GO:0046483,GO:0046700,GO:0046872,GO:0048518,GO:0048519,GO:0048522,GO:0050779,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000000000006515 175.0
HFD3_k127_1122473_24 Protein of unknown function (DUF3048) C-terminal domain - - - 0.00000000000000000000000000000000000000000000003831 185.0
HFD3_k127_1122473_25 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009378,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360 3.6.4.12 0.0000000000000000000000000000000000000000004491 172.0
HFD3_k127_1122473_26 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483,K07667 - - 0.000000000000000000000000000000000001429 148.0
HFD3_k127_1122473_27 Protein of unknown function (DUF421) - - - 0.000000000000000000000000000001715 125.0
HFD3_k127_1122473_28 Peptidase family M48 K03799 - - 0.0000000000000000000008915 94.0
HFD3_k127_1122473_29 Domain of unknown function (DUF4118) - - - 0.00000000000000000003445 100.0
HFD3_k127_1122473_3 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 3.848e-254 822.0
HFD3_k127_1122473_30 Psort location Cytoplasmic, score - - - 0.00000000000001513 84.0
HFD3_k127_1122473_31 - - - - 0.00000000000002003 84.0
HFD3_k127_1122473_32 Preprotein translocase K03210 - - 0.000000000008325 70.0
HFD3_k127_1122473_33 Belongs to the anti-sigma-factor antagonist family - - - 0.000000000631 64.0
HFD3_k127_1122473_34 - - - - 0.0006089 44.0
HFD3_k127_1122473_4 Histidine kinase K07646 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 2.7.13.3 3.538e-240 768.0
HFD3_k127_1122473_5 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009987 605.0
HFD3_k127_1122473_6 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 572.0
HFD3_k127_1122473_7 MgsA AAA+ ATPase C terminal K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 556.0
HFD3_k127_1122473_8 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000596 522.0
HFD3_k127_1122473_9 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 509.0
HFD3_k127_1139747_0 Amidohydrolase family - - - 8.643e-228 711.0
HFD3_k127_1139747_1 decarboxylase K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 595.0
HFD3_k127_1139747_10 Belongs to the peptidase S8 family - - - 0.000003045 57.0
HFD3_k127_1139747_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 532.0
HFD3_k127_1139747_3 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001684 267.0
HFD3_k127_1139747_4 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K00219,K01069 - 1.3.1.34,3.1.2.6 0.00000000000000000000000000000000000000000000000000000002418 211.0
HFD3_k127_1139747_5 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000006342 213.0
HFD3_k127_1139747_6 Iron-sulphur cluster biosynthesis K13628 - - 0.00000000000000000000000000000000000000000004928 164.0
HFD3_k127_1139747_7 oxidation-reduction process K09022 - 3.5.99.10 0.000000000000000000000000000000004655 141.0
HFD3_k127_1139747_8 membrane - - - 0.0000000000000000000000000000001789 134.0
HFD3_k127_1139747_9 Acyltransferase - - - 0.0000004643 60.0
HFD3_k127_1139787_0 Dehydratase family K01687 - 4.2.1.9 6.264e-302 932.0
HFD3_k127_1139787_1 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 3.901e-206 648.0
HFD3_k127_1139787_10 ABC-type dipeptide transport system K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000391 344.0
HFD3_k127_1139787_11 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008484 300.0
HFD3_k127_1139787_12 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001663 274.0
HFD3_k127_1139787_13 cheY-homologous receiver domain K07671 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006126 266.0
HFD3_k127_1139787_14 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000252 233.0
HFD3_k127_1139787_15 PFAM flavin reductase domain protein, FMN-binding - - - 0.000000000000000000000000000000000000000000000000000001122 205.0
HFD3_k127_1139787_16 His Kinase A (phosphoacceptor) domain K07655 GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019538,GO:0030312,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044110,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0046777,GO:0051704,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 0.000000000000000000000000000000000000000000000000000008254 206.0
HFD3_k127_1139787_17 Protein of unknown function (DUF3054) - - - 0.0000000000000000000000000002532 127.0
HFD3_k127_1139787_18 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000001005 113.0
HFD3_k127_1139787_19 ThiS family - - - 0.000000000000000007392 88.0
HFD3_k127_1139787_2 Belongs to the citrate synthase family K01647 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005651 603.0
HFD3_k127_1139787_20 - - - - 0.00002753 52.0
HFD3_k127_1139787_3 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 588.0
HFD3_k127_1139787_4 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 597.0
HFD3_k127_1139787_5 PFAM AMP-dependent synthetase and ligase K02182 - 6.2.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 473.0
HFD3_k127_1139787_6 beta-keto acid cleavage enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 452.0
HFD3_k127_1139787_7 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003454 437.0
HFD3_k127_1139787_8 FMN-dependent dehydrogenase K00101 - 1.1.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 434.0
HFD3_k127_1139787_9 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 380.0
HFD3_k127_1166666_0 ATPase P-type (Transporting), HAD superfamily, subfamily IC - - - 0.0 1058.0
HFD3_k127_1166666_1 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - 4.968e-259 809.0
HFD3_k127_1166666_10 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 287.0
HFD3_k127_1166666_11 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004391 269.0
HFD3_k127_1166666_12 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001542 269.0
HFD3_k127_1166666_13 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000003854 229.0
HFD3_k127_1166666_14 permease - - - 0.0000000000000000000000000000000000000000000000000000000000001564 228.0
HFD3_k127_1166666_15 Sigma-70 region 3 K03090 - - 0.000000000000000000000000000000000000000000000000000003676 202.0
HFD3_k127_1166666_16 - - - - 0.000000000000000000000000000000000000001737 157.0
HFD3_k127_1166666_17 - - - - 0.00000000000000000000000000000000000003184 152.0
HFD3_k127_1166666_18 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046983,GO:0070037,GO:0070038,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.177 0.0000000000000000000000000000000000001627 151.0
HFD3_k127_1166666_19 ACT domain protein - - - 0.000000000000000000000000000000000001145 147.0
HFD3_k127_1166666_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 560.0
HFD3_k127_1166666_20 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.00000000000000000000000004059 115.0
HFD3_k127_1166666_22 sigma factor antagonist activity K04757 - 2.7.11.1 0.000002593 55.0
HFD3_k127_1166666_23 anti-sigma B factor K04757 - 2.7.11.1 0.00006187 52.0
HFD3_k127_1166666_3 Belongs to the proline racemase family K01777 - 5.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 491.0
HFD3_k127_1166666_4 cobalamin binding K20450 - 5.4.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 470.0
HFD3_k127_1166666_5 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 GO:0003674,GO:0003824,GO:0004333,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0071944,GO:0072350 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 453.0
HFD3_k127_1166666_6 Enoyl-(Acyl carrier protein) reductase K00034 - 1.1.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 381.0
HFD3_k127_1166666_7 WYL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 357.0
HFD3_k127_1166666_8 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007863 328.0
HFD3_k127_1166666_9 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 302.0
HFD3_k127_117962_0 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain K21023 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 427.0
HFD3_k127_117962_1 Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 401.0
HFD3_k127_1222864_0 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008653 503.0
HFD3_k127_1222864_1 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 348.0
HFD3_k127_1222864_10 EamA-like transporter family - - - 0.00001096 50.0
HFD3_k127_1222864_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008658 330.0
HFD3_k127_1222864_4 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 286.0
HFD3_k127_1222864_5 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001187 268.0
HFD3_k127_1222864_6 Guanylyl transferase CofC like K14941 - 2.7.7.68 0.000000000000000000000000000000000000000000000000006821 187.0
HFD3_k127_1222864_7 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.000000000000000000000000000000000000000000008092 181.0
HFD3_k127_1222864_8 MOSC domain - - - 0.00000000000000000000000000000000000000000008318 181.0
HFD3_k127_1222864_9 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - 0.00000000000002944 73.0
HFD3_k127_129474_0 acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 396.0
HFD3_k127_129474_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 354.0
HFD3_k127_129474_10 Putative zinc-finger K03088 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000003401 60.0
HFD3_k127_129474_2 PD-(D/E)XK nuclease superfamily K07465 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 336.0
HFD3_k127_129474_3 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000001115 226.0
HFD3_k127_129474_4 CopC domain K14166 - - 0.0000000000000000000000000000000000000000000000000000000006832 224.0
HFD3_k127_129474_5 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000002942 178.0
HFD3_k127_129474_6 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000000009824 152.0
HFD3_k127_129474_7 diacylglycerol O-acyltransferase K00635 GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700 2.3.1.20 0.000000000000000000000000000000001572 132.0
HFD3_k127_129474_8 Domain of unkown function (DUF1775) - - - 0.000000000000000000003342 104.0
HFD3_k127_129474_9 - - - - 0.000000000000006032 80.0
HFD3_k127_1416881_0 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 446.0
HFD3_k127_1416881_1 -O-antigen K02847,K02849,K21003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 445.0
HFD3_k127_1416881_10 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.0000000000000000000000000000000000000000001742 162.0
HFD3_k127_1416881_11 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.000000000000000000000000000000000000000005813 167.0
HFD3_k127_1416881_12 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000002455 156.0
HFD3_k127_1416881_13 protein tyrosine kinase activity K20998 - - 0.0000000000000000000000000000000000000001487 165.0
HFD3_k127_1416881_14 JAB/MPN domain K21140 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006508,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016787,GO:0019344,GO:0019538,GO:0019752,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.13.1.6 0.000000000000000000000000000000000000001205 151.0
HFD3_k127_1416881_15 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.00000000000000000000000000000000003698 138.0
HFD3_k127_1416881_17 Transcriptional regulator - - - 0.0000000000005744 72.0
HFD3_k127_1416881_18 transferase activity, transferring glycosyl groups - - - 0.00000000002926 64.0
HFD3_k127_1416881_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005581 377.0
HFD3_k127_1416881_3 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 332.0
HFD3_k127_1416881_4 Belongs to the glycosyltransferase 26 family K05946 - 2.4.1.187 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007335 296.0
HFD3_k127_1416881_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003388 289.0
HFD3_k127_1416881_6 Belongs to the sigma-70 factor family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001734 272.0
HFD3_k127_1416881_7 Haem-degrading - - - 0.0000000000000000000000000000000000000000000000000000000001521 210.0
HFD3_k127_1416881_8 extracellular polysaccharide biosynthetic process K16692,K20998 - - 0.00000000000000000000000000000000000000000000001034 184.0
HFD3_k127_1416881_9 metallocarboxypeptidase activity K14054 - - 0.0000000000000000000000000000000000000000001119 171.0
HFD3_k127_1501103_0 COG1404 Subtilisin-like serine proteases K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 416.0
HFD3_k127_1501103_1 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 374.0
HFD3_k127_1501103_2 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009114 289.0
HFD3_k127_1501103_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000007343 238.0
HFD3_k127_1501103_4 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000005576 207.0
HFD3_k127_1501103_5 - - - - 0.0000000000000000000000000000000008743 133.0
HFD3_k127_154013_0 2-oxoglutarate dehydrogenase N-terminus K00164 - 1.2.4.2 0.0 1757.0
HFD3_k127_154013_1 RecF/RecN/SMC N terminal domain K03529 - - 0.0 1326.0
HFD3_k127_154013_10 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 475.0
HFD3_k127_154013_11 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 447.0
HFD3_k127_154013_12 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 434.0
HFD3_k127_154013_13 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 417.0
HFD3_k127_154013_14 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009462 372.0
HFD3_k127_154013_15 Zc3h12a-like Ribonuclease NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 364.0
HFD3_k127_154013_16 PFAM LmbE family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 362.0
HFD3_k127_154013_17 Protein of unknown function (DUF455) K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 319.0
HFD3_k127_154013_18 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009265 291.0
HFD3_k127_154013_19 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005075 285.0
HFD3_k127_154013_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0 1063.0
HFD3_k127_154013_20 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002527 280.0
HFD3_k127_154013_21 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003265 260.0
HFD3_k127_154013_22 Bacterial PH domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003086 261.0
HFD3_k127_154013_23 HAD-superfamily hydrolase subfamily IA, variant 3 K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005124 275.0
HFD3_k127_154013_24 Cell envelope-related transcriptional attenuator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002522 265.0
HFD3_k127_154013_25 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000002235 258.0
HFD3_k127_154013_26 Lysyl oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000001386 229.0
HFD3_k127_154013_27 Belongs to the GHMP kinase family K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000001733 220.0
HFD3_k127_154013_28 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000000000000000002745 202.0
HFD3_k127_154013_29 Protein conserved in bacteria K03654 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000003027 209.0
HFD3_k127_154013_3 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.0 1015.0
HFD3_k127_154013_30 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000007102 190.0
HFD3_k127_154013_31 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000343 185.0
HFD3_k127_154013_32 - - - - 0.00000000000000000000000000000000000000000002707 169.0
HFD3_k127_154013_33 Protein of unknown function (DUF4242) - - - 0.00000000000000000000000000000000000000001377 157.0
HFD3_k127_154013_34 Urate oxidase N-terminal - - - 0.0000000000000000000000000000000000000008242 160.0
HFD3_k127_154013_35 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000000000000000006071 151.0
HFD3_k127_154013_37 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000000000003847 139.0
HFD3_k127_154013_38 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.00000000000000000000000000000000005301 137.0
HFD3_k127_154013_39 - - - - 0.0000000000000000000000000000000000543 146.0
HFD3_k127_154013_4 ABC transporter - - - 8.417e-249 774.0
HFD3_k127_154013_40 Ribosomal L28 family K02902 - - 0.00000000000000000000000000004181 117.0
HFD3_k127_154013_41 acyl-CoA dehydrogenase - - - 0.0000000000000000000000002626 122.0
HFD3_k127_154013_42 Cold shock K03704 - - 0.000000000000000000000000271 106.0
HFD3_k127_154013_43 - - - - 0.0000000000000000000000003952 113.0
HFD3_k127_154013_44 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.0000000000000000000002633 97.0
HFD3_k127_154013_46 Fic/DOC family K07341 - - 0.0000000001685 68.0
HFD3_k127_154013_47 amine dehydrogenase activity - - - 0.000006591 53.0
HFD3_k127_154013_48 MRF binding K04498 GO:0000003,GO:0000075,GO:0000076,GO:0000122,GO:0000123,GO:0000228,GO:0000775,GO:0000776,GO:0000777,GO:0000779,GO:0000785,GO:0000790,GO:0000793,GO:0000940,GO:0000976,GO:0000977,GO:0000981,GO:0000982,GO:0000987,GO:0000988,GO:0000989,GO:0001012,GO:0001067,GO:0001076,GO:0001078,GO:0001085,GO:0001091,GO:0001093,GO:0001098,GO:0001099,GO:0001102,GO:0001191,GO:0001227,GO:0001228,GO:0001505,GO:0001654,GO:0001666,GO:0001736,GO:0001738,GO:0001745,GO:0001751,GO:0001752,GO:0001754,GO:0001817,GO:0001818,GO:0001819,GO:0002009,GO:0002039,GO:0002064,GO:0002065,GO:0002066,GO:0002218,GO:0002220,GO:0002223,GO:0002253,GO:0002376,GO:0002429,GO:0002520,GO:0002682,GO:0002684,GO:0002757,GO:0002758,GO:0002764,GO:0002768,GO:0003006,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003684,GO:0003690,GO:0003700,GO:0003712,GO:0003713,GO:0003824,GO:0004402,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005667,GO:0005694,GO:0005700,GO:0005737,GO:0006139,GO:0006325,GO:0006351,GO:0006352,GO:0006355,GO:0006357,GO:0006366,GO:0006367,GO:0006464,GO:0006473,GO:0006474,GO:0006475,GO:0006479,GO:0006725,GO:0006807,GO:0006810,GO:0006836,GO:0006928,GO:0006950,GO:0006996,GO:0007088,GO:0007154,GO:0007163,GO:0007164,GO:0007165,GO:0007166,GO:0007219,GO:0007221,GO:0007224,GO:0007267,GO:0007268,GO:0007269,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007346,GO:0007399,GO:0007416,GO:0007423,GO:0007464,GO:0007610,GO:0007622,GO:0007623,GO:0007626,GO:0008080,GO:0008134,GO:0008140,GO:0008150,GO:0008152,GO:0008213,GO:0008270,GO:0008283,GO:0008347,GO:0008589,GO:0008593,GO:0009058,GO:0009059,GO:0009266,GO:0009314,GO:0009411,GO:0009416,GO:0009605,GO:0009607,GO:0009615,GO:0009628,GO:0009653,GO:0009790,GO:0009887,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010033,GO:0010467,GO:0010468,GO:0010484,GO:0010556,GO:0010557,GO:0010558,GO:0010564,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010646,GO:0010647,GO:0010648,GO:0010941,GO:0016043,GO:0016055,GO:0016070,GO:0016407,GO:0016410,GO:0016477,GO:0016569,GO:0016570,GO:0016571,GO:0016573,GO:0016604,GO:0016605,GO:0016740,GO:0016746,GO:0016747,GO:0018022,GO:0018076,GO:0018130,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019216,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0019827,GO:0019899,GO:0019904,GO:0019953,GO:0022008,GO:0022412,GO:0022414,GO:0022607,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0023061,GO:0030097,GO:0030111,GO:0030154,GO:0030177,GO:0030178,GO:0030182,GO:0030326,GO:0030707,GO:0030718,GO:0030855,GO:0031248,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031347,GO:0031349,GO:0031365,GO:0031570,GO:0031647,GO:0031648,GO:0031974,GO:0031981,GO:0032259,GO:0032479,GO:0032480,GO:0032481,GO:0032501,GO:0032502,GO:0032504,GO:0032648,GO:0032688,GO:0032774,GO:0032793,GO:0032922,GO:0032940,GO:0032991,GO:0033043,GO:0033554,GO:0033613,GO:0034097,GO:0034212,GO:0034641,GO:0034644,GO:0034645,GO:0034654,GO:0034708,GO:0034968,GO:0035097,GO:0035107,GO:0035108,GO:0035113,GO:0035728,GO:0035729,GO:0036211,GO:0036293,GO:0036294,GO:0040011,GO:0040040,GO:0042035,GO:0042036,GO:0042063,GO:0042067,GO:0042221,GO:0042592,GO:0042706,GO:0042733,GO:0042975,GO:0042981,GO:0043067,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0043425,GO:0043426,GO:0043543,GO:0043565,GO:0043618,GO:0043620,GO:0043900,GO:0043901,GO:0043903,GO:0043933,GO:0043966,GO:0043967,GO:0043971,GO:0043974,GO:0043982,GO:0043983,GO:0043993,GO:0044017,GO:0044085,GO:0044093,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044451,GO:0044454,GO:0044464,GO:0044703,GO:0044798,GO:0045088,GO:0045089,GO:0045165,GO:0045357,GO:0045358,GO:0045466,GO:0045475,GO:0045595,GO:0045637,GO:0045747,GO:0045786,GO:0045787,GO:0045892,GO:0045893,GO:0045931,GO:0045934,GO:0045935,GO:0045944,GO:0046332,GO:0046483,GO:0046530,GO:0046552,GO:0046872,GO:0046903,GO:0046914,GO:0046982,GO:0046983,GO:0048056,GO:0048468,GO:0048477,GO:0048511,GO:0048512,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048525,GO:0048534,GO:0048583,GO:0048584,GO:0048585,GO:0048592,GO:0048598,GO:0048609,GO:0048663,GO:0048699,GO:0048729,GO:0048731,GO:0048736,GO:0048749,GO:0048856,GO:0048869,GO:0048870,GO:0050776,GO:0050778,GO:0050789,GO:0050792,GO:0050793,GO:0050794,GO:0050808,GO:0050896,GO:0051090,GO:0051091,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051254,GO:0051276,GO:0051568,GO:0051604,GO:0051641,GO:0051649,GO:0051674,GO:0051704,GO:0051707,GO:0051716,GO:0051726,GO:0051783,GO:0060173,GO:0060255,GO:0060353,GO:0060355,GO:0060429,GO:0060828,GO:0061418,GO:0061733,GO:0065003,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070482,GO:0070555,GO:0070848,GO:0070887,GO:0071214,GO:0071310,GO:0071363,GO:0071453,GO:0071456,GO:0071478,GO:0071482,GO:0071704,GO:0071840,GO:0080090,GO:0080134,GO:0080135,GO:0090068,GO:0090090,GO:0090263,GO:0090304,GO:0090575,GO:0090596,GO:0097159,GO:0097659,GO:0097718,GO:0098586,GO:0098687,GO:0098727,GO:0098916,GO:0099536,GO:0099537,GO:0099643,GO:0104004,GO:0140110,GO:0198738,GO:1900034,GO:1900087,GO:1901222,GO:1901224,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901576,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902493,GO:1902494,GO:1902531,GO:1902533,GO:1902679,GO:1902680,GO:1902806,GO:1902808,GO:1903506,GO:1903507,GO:1903508,GO:1903706,GO:1904837,GO:1905114,GO:1990226,GO:1990234,GO:1990837,GO:2000026,GO:2000045,GO:2000112,GO:2000113,GO:2001141 2.3.1.48 0.0008316 44.0
HFD3_k127_154013_5 Dak1_2 K07030 - - 3.7e-225 709.0
HFD3_k127_154013_6 Hydrolase CocE NonD family K06978 - - 5.287e-215 689.0
HFD3_k127_154013_7 CoA-transferase family III K01796 - 5.1.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 586.0
HFD3_k127_154013_8 Acetylornithine deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 513.0
HFD3_k127_154013_9 Bacterial extracellular solute-binding protein K02055 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 501.0
HFD3_k127_154075_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1403.0
HFD3_k127_154075_1 Anthranilate synthase component I, N terminal region K01657 - 4.1.3.27 2.22e-248 781.0
HFD3_k127_154075_10 xyloglucan:xyloglucosyl transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000002686 231.0
HFD3_k127_154075_11 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000001313 200.0
HFD3_k127_154075_12 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.0000000000000000000000000000000000000000000000004146 178.0
HFD3_k127_154075_13 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000004418 113.0
HFD3_k127_154075_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 5.809e-247 774.0
HFD3_k127_154075_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 503.0
HFD3_k127_154075_4 membrane protein terC K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 404.0
HFD3_k127_154075_5 NhaP-type Na H and K H antiporters with a unique C-terminal domain K11105 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 406.0
HFD3_k127_154075_6 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000593 305.0
HFD3_k127_154075_7 Mitochondrial biogenesis AIM24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004803 273.0
HFD3_k127_154075_8 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000001267 251.0
HFD3_k127_154075_9 Aminomethyltransferase folate-binding domain K06980 - - 0.0000000000000000000000000000000000000000000000000000000000000002706 229.0
HFD3_k127_1561894_0 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 7.672e-232 721.0
HFD3_k127_1561894_1 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 1.466e-221 692.0
HFD3_k127_1561894_10 Bacterial regulatory helix-turn-helix protein, lysR family K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 372.0
HFD3_k127_1561894_11 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005873 362.0
HFD3_k127_1561894_12 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 293.0
HFD3_k127_1561894_13 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000002669 223.0
HFD3_k127_1561894_14 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000009884 240.0
HFD3_k127_1561894_15 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000001202 178.0
HFD3_k127_1561894_16 Protein of unknown function (DUF664) - - - 0.0000000000000000000000000000000000000000000002215 187.0
HFD3_k127_1561894_17 transglycosylase - - - 0.000000000000000000000000000000000000000000001152 177.0
HFD3_k127_1561894_2 Aconitase family (aconitate hydratase) K01681 - 4.2.1.3 1.646e-205 646.0
HFD3_k127_1561894_3 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003486 609.0
HFD3_k127_1561894_4 HAD-superfamily subfamily IB hydrolase, TIGR01490 K15781 - 2.3.1.51,3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 608.0
HFD3_k127_1561894_5 Carboxyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005419 589.0
HFD3_k127_1561894_6 Alkyl sulfatase dimerisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 541.0
HFD3_k127_1561894_7 Oxidoreductase molybdopterin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 467.0
HFD3_k127_1561894_8 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005237 442.0
HFD3_k127_1561894_9 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 438.0
HFD3_k127_1590111_0 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000546 569.0
HFD3_k127_1590111_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 317.0
HFD3_k127_1590111_2 Domain present in PSD-95, Dlg, and ZO-1/2. K08372 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 305.0
HFD3_k127_1590111_3 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002007 276.0
HFD3_k127_1590111_4 TrkA-C domain K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000004271 232.0
HFD3_k127_1590111_5 PFAM TrkA-N domain protein K03499 - - 0.000000000000000000000000000000000000000000000000000000000001899 218.0
HFD3_k127_1590111_6 Nucleic acid binding, OB-fold, tRNA - - - 0.00000000003984 72.0
HFD3_k127_1590111_7 Forms part of the polypeptide exit tunnel K02926 - - 0.0000000004524 64.0
HFD3_k127_1601968_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1436.0
HFD3_k127_1601968_1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term K00441 - 1.12.98.1 1.323e-216 676.0
HFD3_k127_1601968_10 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004881 411.0
HFD3_k127_1601968_11 Transcriptional regulator - GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009405,GO:0010468,GO:0010565,GO:0016020,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0044419,GO:0044464,GO:0050789,GO:0050794,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004916 381.0
HFD3_k127_1601968_12 alpha/beta hydrolase fold K01066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 359.0
HFD3_k127_1601968_13 membrane protein terC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009695 346.0
HFD3_k127_1601968_14 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 351.0
HFD3_k127_1601968_15 Histidine phosphatase superfamily (branch 1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007406 323.0
HFD3_k127_1601968_16 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 331.0
HFD3_k127_1601968_17 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 312.0
HFD3_k127_1601968_18 Phosphatidylinositol - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006964 316.0
HFD3_k127_1601968_19 DJ-1 PfpI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 301.0
HFD3_k127_1601968_2 Ammonium Transporter Family K03320 - - 6.13e-196 624.0
HFD3_k127_1601968_20 Glucose dehydrogenase C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005905 295.0
HFD3_k127_1601968_21 Protein of unknown function (DUF3090) - - - 0.00000000000000000000000000000000000000000000000000000000000001077 225.0
HFD3_k127_1601968_22 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000001776 243.0
HFD3_k127_1601968_23 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000008018 185.0
HFD3_k127_1601968_24 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000009356 174.0
HFD3_k127_1601968_25 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000007072 174.0
HFD3_k127_1601968_26 Belongs to the P(II) protein family K04751 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0008150,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043531,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000006775 166.0
HFD3_k127_1601968_27 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.0000000000000000000000000000000000009007 141.0
HFD3_k127_1601968_28 Protein of unknown function (DUF3107) - - - 0.000000000000000000001665 98.0
HFD3_k127_1601968_3 Histidine kinase K00936 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 594.0
HFD3_k127_1601968_4 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007154 563.0
HFD3_k127_1601968_5 Electron transfer flavoprotein domain K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 468.0
HFD3_k127_1601968_6 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K01459 - 3.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005188 450.0
HFD3_k127_1601968_7 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 452.0
HFD3_k127_1601968_8 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006312 430.0
HFD3_k127_1601968_9 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 400.0
HFD3_k127_1605065_0 Uncharacterised protein family (UPF0182) K09118 - - 3.251e-277 893.0
HFD3_k127_1605065_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 4.839e-276 857.0
HFD3_k127_1605065_10 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 372.0
HFD3_k127_1605065_11 Glycerate kinase family K00865 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 374.0
HFD3_k127_1605065_12 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 374.0
HFD3_k127_1605065_13 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 356.0
HFD3_k127_1605065_14 PFAM Peptidoglycan-binding LysM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 361.0
HFD3_k127_1605065_15 Hydrolase of X-linked nucleoside diphosphate N terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 347.0
HFD3_k127_1605065_16 reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 347.0
HFD3_k127_1605065_17 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 319.0
HFD3_k127_1605065_18 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001658 280.0
HFD3_k127_1605065_19 Chlorite dismutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008113 272.0
HFD3_k127_1605065_2 - - - - 2.901e-250 795.0
HFD3_k127_1605065_20 DNA binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000434 238.0
HFD3_k127_1605065_21 phage tail protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001331 233.0
HFD3_k127_1605065_22 Belongs to the peptidase S16 family K07177 - - 0.00000000000000000000000000000000000000000000000000000000000000000755 246.0
HFD3_k127_1605065_23 Phosphoribulokinase / Uridine kinase family K00855,K00876 - 2.7.1.19,2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000008353 231.0
HFD3_k127_1605065_24 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000006723 246.0
HFD3_k127_1605065_25 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000253 227.0
HFD3_k127_1605065_26 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000002351 229.0
HFD3_k127_1605065_27 PBS lyase HEAT-like repeat - - - 0.00000000000000000000000000000000000000000000000000000000366 208.0
HFD3_k127_1605065_28 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 - - 0.000000000000000000000000000000000000000000000000001309 192.0
HFD3_k127_1605065_29 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000009311 169.0
HFD3_k127_1605065_3 peptidase activity, acting on L-amino acid peptides K01337,K01400,K20276 - 3.4.21.50,3.4.24.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 575.0
HFD3_k127_1605065_30 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000008892 173.0
HFD3_k127_1605065_31 Uracil DNA glycosylase superfamily - - - 0.0000000000000000000000000000000001938 139.0
HFD3_k127_1605065_32 ThiS family K03636 - - 0.00000000000000000000000000001804 120.0
HFD3_k127_1605065_33 Protein of unknown function (DUF3618) - - - 0.000000000000000000000000004474 122.0
HFD3_k127_1605065_34 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.000000000000000000001389 99.0
HFD3_k127_1605065_36 nuclear chromosome segregation K19765 - - 0.000000000000000005418 97.0
HFD3_k127_1605065_38 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.0000000000000009434 88.0
HFD3_k127_1605065_39 Transposase DDE domain K07492 - - 0.0000000000001511 74.0
HFD3_k127_1605065_4 Belongs to the amidase family K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 520.0
HFD3_k127_1605065_41 - - - - 0.00000001684 62.0
HFD3_k127_1605065_42 - - - - 0.00000009259 56.0
HFD3_k127_1605065_43 Belongs to the 'phage' integrase family - - - 0.0000002367 62.0
HFD3_k127_1605065_44 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.000000578 56.0
HFD3_k127_1605065_45 - - - - 0.00009713 50.0
HFD3_k127_1605065_46 AAA ATPase domain - - - 0.0001619 49.0
HFD3_k127_1605065_5 regulation of cell shape K04074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 497.0
HFD3_k127_1605065_6 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 495.0
HFD3_k127_1605065_7 PFAM FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 432.0
HFD3_k127_1605065_8 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 422.0
HFD3_k127_1605065_9 PAC2 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006444 385.0
HFD3_k127_1606357_0 PFAM glycosyl hydrolase BNR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 388.0
HFD3_k127_1606357_1 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000005239 239.0
HFD3_k127_1606357_3 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 0.000000000000000000003022 94.0
HFD3_k127_1838424_0 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 0.0 1057.0
HFD3_k127_1838424_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 5.44e-208 662.0
HFD3_k127_1838424_2 succinate dehydrogenase K00241 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 322.0
HFD3_k127_1838424_3 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000006193 242.0
HFD3_k127_1882499_0 Ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 8.6e-260 814.0
HFD3_k127_1882499_1 Acyl-CoA dehydrogenase, C-terminal domain K14448 - 1.3.8.12 5.945e-248 778.0
HFD3_k127_1882499_10 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009625 389.0
HFD3_k127_1882499_11 phosphatase activity K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 291.0
HFD3_k127_1882499_12 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001736 255.0
HFD3_k127_1882499_13 inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000001077 233.0
HFD3_k127_1882499_14 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000005978 233.0
HFD3_k127_1882499_15 Evidence 4 Homologs of previously reported genes of K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000004287 205.0
HFD3_k127_1882499_16 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000003853 206.0
HFD3_k127_1882499_17 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000001992 198.0
HFD3_k127_1882499_18 Two component transcriptional regulator, LuxR family - - - 0.000000000000000000000000000000000000000000000000004208 196.0
HFD3_k127_1882499_19 nucleotidyltransferase activity - - - 0.000000000000000000000000000000000000000002176 166.0
HFD3_k127_1882499_2 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 1.661e-231 720.0
HFD3_k127_1882499_20 MaoC like domain - - - 0.0000000000000000161 81.0
HFD3_k127_1882499_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00596,K15372 - 2.6.1.55,4.1.1.64 7.835e-225 706.0
HFD3_k127_1882499_4 Ferredoxin oxidoreductase K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007211 564.0
HFD3_k127_1882499_5 HpcH/HpaI aldolase/citrate lyase family K01644,K08691 - 4.1.3.24,4.1.3.25,4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 567.0
HFD3_k127_1882499_6 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 532.0
HFD3_k127_1882499_7 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 499.0
HFD3_k127_1882499_8 Lysylphosphatidylglycerol synthase TM region K07027,K20468 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 417.0
HFD3_k127_1882499_9 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 388.0
HFD3_k127_1939129_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1488.0
HFD3_k127_1939129_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008103 511.0
HFD3_k127_1939129_2 Evidence 5 No homology to any previously reported sequences - - - 0.0002922 49.0
HFD3_k127_1977147_0 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 334.0
HFD3_k127_1977147_1 - - - - 0.00000000000000000000000000000000000000000000000000000000001114 234.0
HFD3_k127_1977147_2 competence protein COMEC - - - 0.000000000000000000000000000000000000000000000000469 198.0
HFD3_k127_1977147_3 - - - - 0.000000000000000000000000000002135 124.0
HFD3_k127_1992658_0 ATPase related to phosphate starvation-inducible protein PhoH K07175 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 612.0
HFD3_k127_1992658_1 WYL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 305.0
HFD3_k127_1992658_2 transcriptional regulator K13573 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003499 303.0
HFD3_k127_1992658_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000003742 196.0
HFD3_k127_1992658_4 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.0000000000000000000000000000000000000000000000006238 179.0
HFD3_k127_1992658_5 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - 0.0000000000000000000000311 101.0
HFD3_k127_1997609_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.4.1.1 6.084e-289 908.0
HFD3_k127_1997609_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901576 2.4.1.18 1.623e-275 885.0
HFD3_k127_1997609_10 Hydrolase of the alpha beta-hydrolase K07020 - - 0.0000000000000000000000000000000000000000000000000001437 199.0
HFD3_k127_1997609_11 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0000000000000000000000000000000000000000000153 169.0
HFD3_k127_1997609_12 AzlC protein - - - 0.00000000000000000000000000000000000000003117 172.0
HFD3_k127_1997609_13 - - - - 0.0000000000000000000000000000000000000004042 160.0
HFD3_k127_1997609_14 NifU-like domain - - - 0.0000000000000000000000000002367 117.0
HFD3_k127_1997609_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 601.0
HFD3_k127_1997609_3 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005236 575.0
HFD3_k127_1997609_4 Major facilitator Superfamily K08369 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 529.0
HFD3_k127_1997609_5 ArgK protein K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 477.0
HFD3_k127_1997609_6 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 470.0
HFD3_k127_1997609_7 PFAM Glycosyl transferase, group 1 K16150 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 441.0
HFD3_k127_1997609_8 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 336.0
HFD3_k127_1997609_9 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007477 297.0
HFD3_k127_2100614_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1671.0
HFD3_k127_2100614_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 8.967e-208 651.0
HFD3_k127_2100614_10 methyltransferase small K00564 - 2.1.1.172 0.000000000000000000000000000000000000000000000000000000000000000000000002255 259.0
HFD3_k127_2100614_11 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000001759 246.0
HFD3_k127_2100614_12 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000006665 203.0
HFD3_k127_2100614_13 Probable molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000002432 209.0
HFD3_k127_2100614_14 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000652 158.0
HFD3_k127_2100614_15 Predicted membrane protein (DUF2079) K07778 - 2.7.13.3 0.0000000000000000000000000000000000000001512 168.0
HFD3_k127_2100614_16 Helix-hairpin-helix DNA-binding motif class 1 - - - 0.0000000000000000000000000000000000005814 142.0
HFD3_k127_2100614_17 Methyltransferase domain - - - 0.00000000000000000000000000000000001017 155.0
HFD3_k127_2100614_18 - - - - 0.0000000000000000000000000004315 117.0
HFD3_k127_2100614_19 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000008583 115.0
HFD3_k127_2100614_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008784 542.0
HFD3_k127_2100614_20 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000006428 108.0
HFD3_k127_2100614_21 enzyme binding K00567,K07443 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 2.1.1.63 0.000000000000000000000003938 106.0
HFD3_k127_2100614_22 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000886 108.0
HFD3_k127_2100614_3 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 554.0
HFD3_k127_2100614_4 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 487.0
HFD3_k127_2100614_5 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 436.0
HFD3_k127_2100614_6 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 421.0
HFD3_k127_2100614_7 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 373.0
HFD3_k127_2100614_8 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 321.0
HFD3_k127_2100614_9 Guanylate kinase homologues. K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000001794 257.0
HFD3_k127_2164621_0 C-terminal, D2-small domain, of ClpB protein K03695 - - 6.218e-255 793.0
HFD3_k127_2164621_1 Adenylosuccinate lyase C-terminus K01756 - 4.3.2.2 6.18e-198 627.0
HFD3_k127_2164621_10 chain release factor K15034 - - 0.00000000001073 78.0
HFD3_k127_2164621_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005809 582.0
HFD3_k127_2164621_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003592 572.0
HFD3_k127_2164621_4 Peptidase family M41 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 444.0
HFD3_k127_2164621_5 Thioesterase-like superfamily K10805 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000978 336.0
HFD3_k127_2164621_6 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 316.0
HFD3_k127_2164621_7 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 308.0
HFD3_k127_2164621_8 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000209 213.0
HFD3_k127_2164621_9 - - - - 0.0000000000000000000000000000000000002953 144.0
HFD3_k127_2200540_0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 606.0
HFD3_k127_2200540_1 EXOIII K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006585 579.0
HFD3_k127_2200540_10 Ferric uptake regulator family K22297 - - 0.00000000000000000000000000000005799 131.0
HFD3_k127_2200540_12 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.000000000000000000000000006593 111.0
HFD3_k127_2200540_2 Cysteine-rich domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 467.0
HFD3_k127_2200540_3 FAD linked K00803 - 2.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 479.0
HFD3_k127_2200540_4 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 410.0
HFD3_k127_2200540_5 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006877 357.0
HFD3_k127_2200540_6 COG1592 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000002461 233.0
HFD3_k127_2200540_7 GHMP kinases N terminal domain K00872 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000003032 229.0
HFD3_k127_2200540_8 RNA-binding protein containing a PIN domain - - - 0.00000000000000000000000000000000000000000000000000000000009769 220.0
HFD3_k127_2200540_9 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000000000000000000000000374 199.0
HFD3_k127_2203933_0 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 458.0
HFD3_k127_2203933_1 cytosine deaminase K01485 - 3.5.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 374.0
HFD3_k127_2203933_2 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004942 344.0
HFD3_k127_2203933_3 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 293.0
HFD3_k127_2203933_4 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000289 238.0
HFD3_k127_2203933_5 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000004283 233.0
HFD3_k127_233027_0 Belongs to the binding-protein-dependent transport system permease family K06020 - 3.6.3.25 1.225e-261 835.0
HFD3_k127_233027_1 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 1.259e-220 692.0
HFD3_k127_233027_10 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 415.0
HFD3_k127_233027_11 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 376.0
HFD3_k127_233027_12 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 347.0
HFD3_k127_233027_13 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 355.0
HFD3_k127_233027_14 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007108 337.0
HFD3_k127_233027_15 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004325 326.0
HFD3_k127_233027_16 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007844 316.0
HFD3_k127_233027_17 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 320.0
HFD3_k127_233027_18 HMGL-like K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002935 274.0
HFD3_k127_233027_19 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004906 283.0
HFD3_k127_233027_2 Transmembrane protein of unknown function (DUF3556) - - - 1.261e-213 678.0
HFD3_k127_233027_20 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001894 274.0
HFD3_k127_233027_21 Polyprenyl synthetase K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000004098 269.0
HFD3_k127_233027_22 CHRD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001116 255.0
HFD3_k127_233027_23 PFAM ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000001913 240.0
HFD3_k127_233027_24 Domain of unknown function (DUF1989) K09967 - - 0.0000000000000000000000000000000000000000000000000000000000007836 216.0
HFD3_k127_233027_25 polysaccharide catabolic process K03478 - 3.5.1.105 0.00000000000000000000000000000000000000000000000000000000002264 220.0
HFD3_k127_233027_26 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000001363 217.0
HFD3_k127_233027_27 Cobalamin B12-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000002088 211.0
HFD3_k127_233027_28 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000121 171.0
HFD3_k127_233027_29 Periplasmic binding protein - - - 0.00000000000000000000000000000000000003943 160.0
HFD3_k127_233027_3 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 9.166e-213 673.0
HFD3_k127_233027_30 homoserine kinase activity K18844 - - 0.00000000000000000000000000000000000242 153.0
HFD3_k127_233027_31 lycopene cyclase - - - 0.00000000000000000000000000000000001466 141.0
HFD3_k127_233027_32 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000002732 137.0
HFD3_k127_233027_33 Polysaccharide pyruvyl transferase - - - 0.0000000000000000000000000000000009411 150.0
HFD3_k127_233027_34 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000679 139.0
HFD3_k127_233027_35 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000005773 124.0
HFD3_k127_233027_36 lycopene cyclase - - - 0.0000000000000000000000000000917 118.0
HFD3_k127_233027_37 carotenoid biosynthetic process - - - 0.00000000000000000000000003428 119.0
HFD3_k127_233027_38 hydroxylase K15746 - 1.14.15.24 0.000000000000000000000003817 115.0
HFD3_k127_233027_39 Glycosyl transferases group 1 - - - 0.0000000000000000001505 100.0
HFD3_k127_233027_4 Flavin containing amine oxidoreductase - - - 1.148e-200 634.0
HFD3_k127_233027_40 PFAM Aldo keto reductase family - - - 0.0000004386 55.0
HFD3_k127_233027_5 Flavin containing amine oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 559.0
HFD3_k127_233027_6 acyl-CoA dehydrogenase K00248,K11410 GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0019395,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681 1.3.8.1,1.3.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 521.0
HFD3_k127_233027_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004604 527.0
HFD3_k127_233027_8 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006044 526.0
HFD3_k127_233027_9 COG COG1132 ABC-type multidrug transport system ATPase and permease components Defense mechanisms K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007996 549.0
HFD3_k127_2374934_0 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2307.0
HFD3_k127_2374934_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.17.4.1 0.0 1240.0
HFD3_k127_2374934_10 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 5.886e-195 617.0
HFD3_k127_2374934_11 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 566.0
HFD3_k127_2374934_12 cytochrome p450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004479 516.0
HFD3_k127_2374934_13 Phosphoribosyl transferase domain K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008939 518.0
HFD3_k127_2374934_14 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 501.0
HFD3_k127_2374934_15 Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009544 491.0
HFD3_k127_2374934_16 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 494.0
HFD3_k127_2374934_17 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 482.0
HFD3_k127_2374934_18 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 471.0
HFD3_k127_2374934_19 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 464.0
HFD3_k127_2374934_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K02567 - 1.17.1.9 0.0 1200.0
HFD3_k127_2374934_20 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 441.0
HFD3_k127_2374934_21 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 442.0
HFD3_k127_2374934_22 Mur ligase family, glutamate ligase domain K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 448.0
HFD3_k127_2374934_23 Acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006984 440.0
HFD3_k127_2374934_24 TOBE domain K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 424.0
HFD3_k127_2374934_25 Bacterial extracellular solute-binding protein K02055,K11069 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 395.0
HFD3_k127_2374934_26 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 387.0
HFD3_k127_2374934_27 D-ala D-ala ligase N-terminus K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 407.0
HFD3_k127_2374934_28 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 381.0
HFD3_k127_2374934_29 Thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009422 329.0
HFD3_k127_2374934_3 haloacid dehalogenase-like hydrolase - - - 0.0 1124.0
HFD3_k127_2374934_30 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 342.0
HFD3_k127_2374934_31 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009566 320.0
HFD3_k127_2374934_32 Histidine biosynthesis protein K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005882 318.0
HFD3_k127_2374934_33 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008619 311.0
HFD3_k127_2374934_34 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 311.0
HFD3_k127_2374934_35 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 305.0
HFD3_k127_2374934_36 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008669 301.0
HFD3_k127_2374934_37 Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol K15520 - 2.3.1.189 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007379 287.0
HFD3_k127_2374934_38 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006599 278.0
HFD3_k127_2374934_39 Binding-protein-dependent transport system inner membrane component K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003265 270.0
HFD3_k127_2374934_4 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 - 1.249e-308 962.0
HFD3_k127_2374934_40 transcriptional regulator K09017 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001048 261.0
HFD3_k127_2374934_41 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000005826 261.0
HFD3_k127_2374934_42 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000004472 252.0
HFD3_k127_2374934_43 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000003081 240.0
HFD3_k127_2374934_44 heme binding K06401,K21472 - - 0.0000000000000000000000000000000000000000000000000000000000000002718 238.0
HFD3_k127_2374934_45 CHAT domain - - - 0.00000000000000000000000000000000000000000000000000000000000005451 245.0
HFD3_k127_2374934_46 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000002478 201.0
HFD3_k127_2374934_47 exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000001173 203.0
HFD3_k127_2374934_48 Putative FMN-binding domain K07734 - - 0.000000000000000000000000000000000000000000000000000007592 201.0
HFD3_k127_2374934_49 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000008313 190.0
HFD3_k127_2374934_5 Domain of unknown function (DUF2088) - - - 1.256e-276 867.0
HFD3_k127_2374934_50 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000000000000000000000000000001305 189.0
HFD3_k127_2374934_51 AsnC family K03718 - - 0.000000000000000000000000000000000000000000000000000215 193.0
HFD3_k127_2374934_52 COG1177 ABC-type spermidine putrescine transport system, permease component II K11070,K11074 - - 0.0000000000000000000000000000000000000000000000000002214 208.0
HFD3_k127_2374934_53 - - - - 0.000000000000000000000000000000000000000000000000001409 187.0
HFD3_k127_2374934_54 AsnC family transcriptional regulator K03719 - - 0.000000000000000000000000000000000000000000000000002479 187.0
HFD3_k127_2374934_55 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000002567 176.0
HFD3_k127_2374934_56 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07032 - - 0.0000000000000000000000000000000000000000006477 167.0
HFD3_k127_2374934_57 Belongs to the UPF0502 family K09915 - - 0.00000000000000000000000000000000000000000343 162.0
HFD3_k127_2374934_58 competence protein COMEC - - - 0.0000000000000000000000000000000000000005145 173.0
HFD3_k127_2374934_59 - - - - 0.0000000000000000000000000000000000005209 146.0
HFD3_k127_2374934_6 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 1.4e-259 805.0
HFD3_k127_2374934_60 N-acetylmuramoyl-L-alanine amidase - - - 0.0000000000000000000000000000000001935 142.0
HFD3_k127_2374934_61 Tetratricopeptide repeat - - - 0.000000000000000000000000000000002396 137.0
HFD3_k127_2374934_62 Uncharacterized protein conserved in bacteria (DUF2087) - - - 0.000000000000000000000000000000005338 145.0
HFD3_k127_2374934_64 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000004812 121.0
HFD3_k127_2374934_65 translation initiation factor activity - - - 0.0000000000000000000000000001363 132.0
HFD3_k127_2374934_66 - - - - 0.000000000000000000000000001748 123.0
HFD3_k127_2374934_67 - - - - 0.00000000000000000000000005552 111.0
HFD3_k127_2374934_68 Protein of unknown function (DUF983) - - - 0.000000000000000000000002649 107.0
HFD3_k127_2374934_69 - - - - 0.00000000000000000000002831 106.0
HFD3_k127_2374934_7 Oligopeptidase F K08602 - - 5.893e-247 787.0
HFD3_k127_2374934_70 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.000000000000000003647 94.0
HFD3_k127_2374934_71 LysM domain - - - 0.000000000000000004053 92.0
HFD3_k127_2374934_72 DnaJ-class molecular chaperone with C-terminal Zn finger domain K03686 - - 0.000000000000001459 86.0
HFD3_k127_2374934_73 Belongs to the peptidase S26 family K13280 - 3.4.21.89 0.0000000004245 73.0
HFD3_k127_2374934_74 - - - - 0.0000000004914 62.0
HFD3_k127_2374934_76 LysM domain - - - 0.000001029 57.0
HFD3_k127_2374934_78 ParE toxin of type II toxin-antitoxin system, parDE K19092 - - 0.0005328 49.0
HFD3_k127_2374934_8 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 1.393e-235 736.0
HFD3_k127_2374934_9 Belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 1.652e-234 732.0
HFD3_k127_2404988_0 Glycine cleavage system P-protein K00281,K00283 - 1.4.4.2 0.0 1291.0
HFD3_k127_2404988_1 Glycine cleavage T-protein C-terminal barrel domain K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007984 454.0
HFD3_k127_2404988_10 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000004748 238.0
HFD3_k127_2404988_11 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.000000000000000000000000000000000000000000000000000000000000000002758 236.0
HFD3_k127_2404988_12 peptidase activity K01286 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000005559 241.0
HFD3_k127_2404988_13 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000000000000000000000000000000000000195 232.0
HFD3_k127_2404988_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000002594 230.0
HFD3_k127_2404988_15 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000002144 235.0
HFD3_k127_2404988_16 Histidine triad (Hit) protein K02503 - - 0.000000000000000000000000000000000000000000000000000000207 197.0
HFD3_k127_2404988_17 Inosine-uridine preferring nucleoside hydrolase K01239 - 3.2.2.1 0.0000000000000000000000000000000000000000000000000004143 202.0
HFD3_k127_2404988_18 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000232 186.0
HFD3_k127_2404988_2 Pyridoxal-dependent decarboxylase conserved domain K01634 - 4.1.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 388.0
HFD3_k127_2404988_20 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000001059 179.0
HFD3_k127_2404988_21 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000004717 171.0
HFD3_k127_2404988_23 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000000000000003887 169.0
HFD3_k127_2404988_24 CHASE - - - 0.00000000000000000000000000003304 132.0
HFD3_k127_2404988_25 thiolester hydrolase activity K17362 - - 0.00000000000000000000000001611 126.0
HFD3_k127_2404988_27 Alpha/beta hydrolase family K06889 - - 0.00000000001657 76.0
HFD3_k127_2404988_28 - - - - 0.000000001226 72.0
HFD3_k127_2404988_29 AAA ATPase domain - - - 0.000001508 61.0
HFD3_k127_2404988_3 metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 349.0
HFD3_k127_2404988_30 - - - - 0.00004899 56.0
HFD3_k127_2404988_31 Transposase, Mutator family - - - 0.0003881 44.0
HFD3_k127_2404988_4 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008814 328.0
HFD3_k127_2404988_5 SOS response associated peptidase (SRAP) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 302.0
HFD3_k127_2404988_6 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000019 275.0
HFD3_k127_2404988_7 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001444 278.0
HFD3_k127_2404988_8 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008591 288.0
HFD3_k127_2404988_9 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001983 266.0
HFD3_k127_2446334_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 2.384e-222 698.0
HFD3_k127_2446334_1 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 373.0
HFD3_k127_2446334_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 366.0
HFD3_k127_2446334_3 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000000000000006626 188.0
HFD3_k127_2446334_4 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000000000003624 164.0
HFD3_k127_2446334_5 - - - - 0.000000000000000000000000000000000000000004201 165.0
HFD3_k127_2446334_6 Ribosomal protein S16 K02959 - - 0.00000000000000000000000000000000292 130.0
HFD3_k127_2446334_7 Protein of unknown function (DUF952) - - - 0.000000000000000000000001499 117.0
HFD3_k127_2446334_8 Belongs to the UPF0109 family K06960 GO:0008150,GO:0040007 - 0.00000000000000000000001059 106.0
HFD3_k127_2446334_9 - - - - 0.00000000000000000003136 107.0
HFD3_k127_2523883_0 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 1.317e-216 687.0
HFD3_k127_2523883_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 1.995e-207 653.0
HFD3_k127_2523883_10 Recombinase - - - 0.00002177 48.0
HFD3_k127_2523883_2 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003887 602.0
HFD3_k127_2523883_3 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 604.0
HFD3_k127_2523883_4 Homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 598.0
HFD3_k127_2523883_5 AlkA N-terminal domain K13529 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 567.0
HFD3_k127_2523883_6 Major Facilitator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003161 300.0
HFD3_k127_2523883_7 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005147 274.0
HFD3_k127_2523883_8 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000478 214.0
HFD3_k127_2562195_0 Domain present in PSD-95, Dlg, and ZO-1/2. K08372 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007325 301.0
HFD3_k127_2562195_1 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003445 281.0
HFD3_k127_2562195_2 TrkA-C domain K03499 - - 0.00000000000000000000000000000000000000000000000000000000000007892 229.0
HFD3_k127_2562195_3 Potassium transporter TrkA K03499 - - 0.000000000000000000000000000000000000000000000000000000000008756 216.0
HFD3_k127_2562195_4 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000000000165 197.0
HFD3_k127_2562195_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000304 81.0
HFD3_k127_2562195_6 Nucleic acid binding, OB-fold, tRNA - - - 0.000000000003091 73.0
HFD3_k127_2562195_7 Amino acid permease - - - 0.000003036 50.0
HFD3_k127_2744348_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0 1119.0
HFD3_k127_2744348_1 FAD dependent oxidoreductase - - - 7.262e-205 664.0
HFD3_k127_2744348_10 3-methyladenine DNA glycosylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009802 345.0
HFD3_k127_2744348_11 Xanthine dehydrogenase iron-sulfur cluster and FAD-binding subunit A K13481 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 315.0
HFD3_k127_2744348_12 PFAM Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 302.0
HFD3_k127_2744348_13 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004639 297.0
HFD3_k127_2744348_14 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 295.0
HFD3_k127_2744348_15 phosphoribosyltransferase K07101 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002766 278.0
HFD3_k127_2744348_16 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000007123 245.0
HFD3_k127_2744348_17 Evidence 5 No homology to any previously reported sequences K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000005589 248.0
HFD3_k127_2744348_18 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000768 237.0
HFD3_k127_2744348_19 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000004528 220.0
HFD3_k127_2744348_2 Domain of unknown function (DUF3367) K16648 - - 2.336e-198 655.0
HFD3_k127_2744348_20 Evidence 5 No homology to any previously reported sequences K14340 - - 0.000000000000000000000000000000000000000000000000000000000005251 228.0
HFD3_k127_2744348_21 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000006749 210.0
HFD3_k127_2744348_22 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000004744 193.0
HFD3_k127_2744348_23 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000001188 154.0
HFD3_k127_2744348_24 Amidohydrolase family K01485 - 3.5.4.1 0.00000000000000000000000000005097 119.0
HFD3_k127_2744348_3 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 528.0
HFD3_k127_2744348_4 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 453.0
HFD3_k127_2744348_5 Belongs to the ABC transporter superfamily K02031,K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007956 452.0
HFD3_k127_2744348_6 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006638 380.0
HFD3_k127_2744348_7 integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 371.0
HFD3_k127_2744348_8 Creatininase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007225 364.0
HFD3_k127_2744348_9 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 346.0
HFD3_k127_2760629_0 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000003201 133.0
HFD3_k127_2771436_0 Belongs to the GcvT family K19191 GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006575,GO:0006576,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008480,GO:0009056,GO:0009063,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016491,GO:0016645,GO:0019695,GO:0019752,GO:0019842,GO:0031406,GO:0031974,GO:0033218,GO:0034641,GO:0035999,GO:0036094,GO:0042133,GO:0042135,GO:0042219,GO:0042402,GO:0042426,GO:0042558,GO:0043167,GO:0043168,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0046483,GO:0046653,GO:0046997,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0055114,GO:0065007,GO:0065008,GO:0070013,GO:0071704,GO:0072341,GO:0097159,GO:0097164,GO:1901052,GO:1901053,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.5.3.19 0.0 1326.0
HFD3_k127_2771436_1 Belongs to the GcvT family - - - 0.0 1070.0
HFD3_k127_2771436_10 Choline/ethanolamine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 364.0
HFD3_k127_2771436_11 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003832 331.0
HFD3_k127_2771436_12 Electron transfer flavoprotein domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000478 287.0
HFD3_k127_2771436_13 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008399 270.0
HFD3_k127_2771436_14 Substrate binding domain of ABC-type glycine betaine transport system K02002 - - 0.000000000000000000000000000000000000000000000000000000000000000002307 241.0
HFD3_k127_2771436_15 Bacterial transcriptional regulator - - - 0.0000000000000000000000000000000000000000006317 166.0
HFD3_k127_2771436_16 gntR family - - - 0.0000000000000000000000000000006721 133.0
HFD3_k127_2771436_2 FAD dependent oxidoreductase K19191 - 1.5.3.19 0.0 1057.0
HFD3_k127_2771436_3 GMC oxidoreductase K00108 - 1.1.99.1 3.007e-287 890.0
HFD3_k127_2771436_4 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 7.367e-278 863.0
HFD3_k127_2771436_5 von Willebrand factor (vWF) type A domain - - - 8.419e-235 733.0
HFD3_k127_2771436_6 Saccharopine dehydrogenase C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 453.0
HFD3_k127_2771436_7 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 422.0
HFD3_k127_2771436_8 glycine betaine K02000 - 3.6.3.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 410.0
HFD3_k127_2771436_9 ABC-type proline glycine betaine transport system permease component K02001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 426.0
HFD3_k127_2853896_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 1.724e-244 759.0
HFD3_k127_2853896_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 4.038e-209 655.0
HFD3_k127_2853896_10 Phosphorylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000007408 220.0
HFD3_k127_2853896_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 511.0
HFD3_k127_2853896_3 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 408.0
HFD3_k127_2853896_4 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 389.0
HFD3_k127_2853896_5 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 369.0
HFD3_k127_2853896_6 Ribosomal protein S2 K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 365.0
HFD3_k127_2853896_7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007962 348.0
HFD3_k127_2853896_8 mannose-6-phosphate isomerase K01809 - 5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001063 280.0
HFD3_k127_2853896_9 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001332 262.0
HFD3_k127_2864661_0 Phosphoribosylglycinamide synthetase, C domain K01945,K11788 - 6.3.3.1,6.3.4.13 4.989e-297 937.0
HFD3_k127_2864661_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 5.962e-290 905.0
HFD3_k127_2864661_2 VWA domain containing CoxE-like protein K07161 - - 1.216e-260 817.0
HFD3_k127_2864661_3 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 2.635e-251 784.0
HFD3_k127_2864661_4 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 1.542e-239 758.0
HFD3_k127_2864661_5 SAICAR synthetase K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004931 418.0
HFD3_k127_2864661_6 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006348 305.0
HFD3_k127_2864661_7 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000002655 225.0
HFD3_k127_2864661_8 Lysylphosphatidylglycerol synthase TM region K07027,K14205,K20468 - 2.3.2.3 0.00001269 52.0
HFD3_k127_2895940_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 2.125e-302 949.0
HFD3_k127_2895940_1 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 4.151e-287 893.0
HFD3_k127_2895940_10 Putative peptidoglycan binding domain - - - 0.00000000000000000000000000000000000214 145.0
HFD3_k127_2895940_11 WD40-like Beta Propeller Repeat - - - 0.000000000000687 76.0
HFD3_k127_2895940_2 PFAM phenylalanine histidine ammonia-lyase K01745 - 4.3.1.3 8.03e-207 655.0
HFD3_k127_2895940_3 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004904 509.0
HFD3_k127_2895940_4 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 501.0
HFD3_k127_2895940_5 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005849 466.0
HFD3_k127_2895940_6 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002002 283.0
HFD3_k127_2895940_7 Glycosylase K05522 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000001187 215.0
HFD3_k127_2895940_8 Histidine kinase K07682 GO:0000166,GO:0000287,GO:0001666,GO:0003032,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009593,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0019826,GO:0020037,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042165,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0051606,GO:0051775,GO:0051776,GO:0070025,GO:0070026,GO:0070482,GO:0070483,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 0.00000000000000000000000000000000000000000000000004256 196.0
HFD3_k127_2895940_9 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000001588 186.0
HFD3_k127_2928619_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.0 1039.0
HFD3_k127_2928619_1 protein synonym multiple resistance and pH homeostasis protein A K00341,K05565 - 1.6.5.3 6.117e-246 779.0
HFD3_k127_2928619_10 Belongs to the complex I subunit 6 family K00339,K05578 - 1.6.5.3 0.000000000000000000000000000000000000000000000000006918 187.0
HFD3_k127_2928619_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000000000001452 151.0
HFD3_k127_2928619_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00332 - 1.6.5.3 0.00000000000000000000000000000004263 134.0
HFD3_k127_2928619_13 TIGRFAM conserved repeat domain - - - 0.00000000000000000000000000000005552 145.0
HFD3_k127_2928619_14 Proton-conducting membrane transporter K03879 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0016020,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464 1.6.5.3 0.0004132 43.0
HFD3_k127_2928619_2 Protein synonym NADH dehydrogenase I subunit M K00342 - 1.6.5.3 1.782e-240 752.0
HFD3_k127_2928619_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.184e-230 717.0
HFD3_k127_2928619_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 1.366e-210 664.0
HFD3_k127_2928619_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 551.0
HFD3_k127_2928619_6 acr, cog1565 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 379.0
HFD3_k127_2928619_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 318.0
HFD3_k127_2928619_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 306.0
HFD3_k127_2928619_9 Protein of unknown function (DUF520) K09767 - - 0.0000000000000000000000000000000000000000000000000000000000000000002723 232.0
HFD3_k127_2967513_0 CoA binding domain - - - 1.9e-322 1001.0
HFD3_k127_2967513_1 Proteasomal ATPase OB/ID domain K13527 - - 3.425e-300 927.0
HFD3_k127_2967513_10 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 385.0
HFD3_k127_2967513_11 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 - 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 367.0
HFD3_k127_2967513_12 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 - 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 325.0
HFD3_k127_2967513_13 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 322.0
HFD3_k127_2967513_14 Belongs to the UPF0271 (lamB) family K07160 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 285.0
HFD3_k127_2967513_15 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009805 284.0
HFD3_k127_2967513_16 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001237 287.0
HFD3_k127_2967513_17 transcriptional regulator K09017 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006604 278.0
HFD3_k127_2967513_18 Allophanate hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004719 257.0
HFD3_k127_2967513_19 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000278 243.0
HFD3_k127_2967513_2 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K13571 - 6.3.1.19 7.803e-277 854.0
HFD3_k127_2967513_21 Allophanate hydrolase subunit 1 - - - 0.000000000000000000000000000000000000000000000000000000000001406 222.0
HFD3_k127_2967513_22 NUDIX hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000001982 211.0
HFD3_k127_2967513_23 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000001769 211.0
HFD3_k127_2967513_24 Peptidase S16, lon domain protein K01338,K07157 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000007893 211.0
HFD3_k127_2967513_25 Belongs to the FPG family K05522 - 4.2.99.18 0.000000000000000000000000000000000000000000000000006278 187.0
HFD3_k127_2967513_26 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000001164 176.0
HFD3_k127_2967513_27 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000006366 159.0
HFD3_k127_2967513_28 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.000000000000000000000000000000000003817 158.0
HFD3_k127_2967513_29 lipid kinase activity - - - 0.00000000000000000000000000000000006926 141.0
HFD3_k127_2967513_3 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 6.202e-276 870.0
HFD3_k127_2967513_30 protein secretion K03116,K03117 GO:0003674,GO:0005215 - 0.000000000000000000000006867 106.0
HFD3_k127_2967513_31 - - - - 0.00000000000000000000007969 106.0
HFD3_k127_2967513_32 SnoaL-like domain - - - 0.00000000000000000004293 96.0
HFD3_k127_2967513_33 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 GO:0003674,GO:0003824,GO:0004112,GO:0004114,GO:0004115,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006163,GO:0006195,GO:0006198,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008081,GO:0008150,GO:0008152,GO:0008199,GO:0008663,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009187,GO:0009214,GO:0009259,GO:0009261,GO:0009405,GO:0009987,GO:0016043,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042301,GO:0042545,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0045229,GO:0046058,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0051704,GO:0055086,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.4.53 0.00000000000000000008214 103.0
HFD3_k127_2967513_34 Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation K13570 - - 0.0000000000000000004283 88.0
HFD3_k127_2967513_35 - - - - 0.00000000000000005347 88.0
HFD3_k127_2967513_36 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.000000000002451 70.0
HFD3_k127_2967513_4 Pup-ligase protein K20814 - 3.5.1.119 2.416e-241 753.0
HFD3_k127_2967513_5 DSHCT K03727 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 3.132e-236 760.0
HFD3_k127_2967513_6 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006947 496.0
HFD3_k127_2967513_7 4Fe-4S dicluster domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000451 486.0
HFD3_k127_2967513_8 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004445 419.0
HFD3_k127_2967513_9 Peptidase, M20 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000296 396.0
HFD3_k127_3030906_0 Cytochrome C assembly protein K02198,K04016 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 509.0
HFD3_k127_3030906_1 Winged helix DNA-binding domain K09927 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000704 467.0
HFD3_k127_3030906_10 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000001517 221.0
HFD3_k127_3030906_11 cell redox homeostasis K02199 - - 0.00000000000000000000000000000000000000000000000853 179.0
HFD3_k127_3030906_12 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000002826 174.0
HFD3_k127_3030906_13 subunit of a heme lyase K02200 - - 0.00000000000000000000000000000000000000006027 158.0
HFD3_k127_3030906_16 phosphohistidine phosphatase, SixA K03574,K08296 - 3.6.1.55 0.0000000000000000000000000000001127 139.0
HFD3_k127_3030906_17 protein kinase activity - - - 0.00000000000000000002221 94.0
HFD3_k127_3030906_2 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004438 355.0
HFD3_k127_3030906_3 DEAD-like helicases superfamily K03724,K06877 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 311.0
HFD3_k127_3030906_4 Sortase family K07284 - 3.4.22.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009988 314.0
HFD3_k127_3030906_5 Cytochrome C assembly protein K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005357 309.0
HFD3_k127_3030906_6 ATPases associated with a variety of cellular activities K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 287.0
HFD3_k127_3030906_7 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005011 268.0
HFD3_k127_3030906_8 CcmB protein K02194 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009652 272.0
HFD3_k127_3030906_9 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000008961 233.0
HFD3_k127_308158_0 4Fe-4S dicluster domain - - - 0.0 1198.0
HFD3_k127_308158_1 Heat shock 70 kDa protein K04043 - - 0.0 1034.0
HFD3_k127_308158_10 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 358.0
HFD3_k127_308158_11 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004778 349.0
HFD3_k127_308158_12 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 342.0
HFD3_k127_308158_13 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 338.0
HFD3_k127_308158_14 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 325.0
HFD3_k127_308158_15 May catalyze the transamination reaction in phenylalanine biosynthesis K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 319.0
HFD3_k127_308158_16 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005011 301.0
HFD3_k127_308158_17 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 325.0
HFD3_k127_308158_18 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001112 296.0
HFD3_k127_308158_19 sugar isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009502 280.0
HFD3_k127_308158_2 metallocarboxypeptidase activity - - - 4.54e-253 807.0
HFD3_k127_308158_20 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002529 273.0
HFD3_k127_308158_21 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007742 267.0
HFD3_k127_308158_22 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000002085 257.0
HFD3_k127_308158_23 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002274 255.0
HFD3_k127_308158_24 Response regulator receiver domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000904 255.0
HFD3_k127_308158_25 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002021 246.0
HFD3_k127_308158_26 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000001378 239.0
HFD3_k127_308158_27 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000225 238.0
HFD3_k127_308158_28 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000008366 211.0
HFD3_k127_308158_29 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000002425 198.0
HFD3_k127_308158_3 UDP-glucoronosyl and UDP-glucosyl transferase - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0009058,GO:0009247,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0020012,GO:0030682,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044464,GO:0046467,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071704,GO:0071944,GO:0075136,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 2.322e-194 614.0
HFD3_k127_308158_30 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000482 202.0
HFD3_k127_308158_31 NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.0000000000000000000000000000000000000000000004945 184.0
HFD3_k127_308158_32 Flavodoxin reductases ferredoxin-NADPH reductases family 1 - - - 0.000000000000000000000000000000000000000000003649 172.0
HFD3_k127_308158_33 Aminoglycoside phosphotransferase K16146 - 2.7.1.175 0.000000000000000000000000000000000000000000007259 175.0
HFD3_k127_308158_34 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000004075 168.0
HFD3_k127_308158_35 COGs COG0673 dehydrogenase and related protein K00010 - 1.1.1.18,1.1.1.369 0.0000000000000000000000000000000000000000002363 172.0
HFD3_k127_308158_36 Binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000000000006145 164.0
HFD3_k127_308158_37 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000001545 164.0
HFD3_k127_308158_38 helix_turn_helix, mercury resistance K13640 - - 0.0000000000000000000000000000000000003554 153.0
HFD3_k127_308158_39 B domain of TMEM189, localisation domain K20656 - - 0.000000000000000000000000000000000001301 148.0
HFD3_k127_308158_4 MMPL family K06994 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 547.0
HFD3_k127_308158_40 Peptidoglycan-binding domain 1 protein K07260,K21449 - 3.4.17.14 0.000000000000000000000000000000000003788 158.0
HFD3_k127_308158_41 PspC domain - - - 0.00000000000000000000000000000000000841 151.0
HFD3_k127_308158_42 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000000007551 122.0
HFD3_k127_308158_43 cyclic nucleotide binding K10914 - - 0.0000000000000000000000000006997 120.0
HFD3_k127_308158_44 Diguanylate cyclase - GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0032879,GO:0042710,GO:0044010,GO:0044464,GO:0044764,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051270,GO:0051271,GO:0051704,GO:0052621,GO:0065007,GO:0071944,GO:0090605,GO:0090609 - 0.00000000000000000000000388 116.0
HFD3_k127_308158_45 - - - - 0.0000000000000000000002115 103.0
HFD3_k127_308158_46 Acetyltransferases including N-acetylases of ribosomal proteins - - - 0.0000000000000000000002763 102.0
HFD3_k127_308158_47 - - - - 0.0000000000000000000004796 101.0
HFD3_k127_308158_48 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.0000000000000000003806 91.0
HFD3_k127_308158_49 PFAM PspC domain protein - - - 0.000000000000000006431 99.0
HFD3_k127_308158_5 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 517.0
HFD3_k127_308158_51 Fibronectin type 3 domain - - - 0.000000000000078 85.0
HFD3_k127_308158_52 FAD binding domain - - - 0.000000000001834 79.0
HFD3_k127_308158_53 CsbD-like - - - 0.00000000002358 67.0
HFD3_k127_308158_6 L-lysine 6-monooxygenase (NADPH-requiring) K07222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 459.0
HFD3_k127_308158_7 TIGRFAM luciferase family oxidoreductase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 435.0
HFD3_k127_308158_8 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007583 401.0
HFD3_k127_308158_9 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 400.0
HFD3_k127_3108548_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0 1033.0
HFD3_k127_3108548_1 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 0.0 1003.0
HFD3_k127_3108548_10 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 387.0
HFD3_k127_3108548_11 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007239 372.0
HFD3_k127_3108548_12 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005706 363.0
HFD3_k127_3108548_13 His Kinase A (phosphoacceptor) domain K07653 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 361.0
HFD3_k127_3108548_14 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007677 338.0
HFD3_k127_3108548_15 Neutral zinc metallopeptidase K07054 GO:0005575,GO:0005576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 316.0
HFD3_k127_3108548_16 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07669,K07672 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 307.0
HFD3_k127_3108548_17 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 315.0
HFD3_k127_3108548_18 Protein of unknown function (DUF418) K07148 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000311 316.0
HFD3_k127_3108548_19 Alanine racemase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 304.0
HFD3_k127_3108548_2 geranylgeranyl reductase activity K00313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 561.0
HFD3_k127_3108548_20 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004585 254.0
HFD3_k127_3108548_21 Electron transfer flavoprotein alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004302 256.0
HFD3_k127_3108548_22 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000009888 236.0
HFD3_k127_3108548_23 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000001212 233.0
HFD3_k127_3108548_24 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000001252 237.0
HFD3_k127_3108548_25 Virulence factor BrkB - - - 0.00000000000000000000000000000000000000000000000000000000000008499 225.0
HFD3_k127_3108548_26 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000001793 231.0
HFD3_k127_3108548_27 Domain of unknown function (DUF4395) - - - 0.0000000000000000000000000000000000000000000001251 174.0
HFD3_k127_3108548_28 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000000000000000000000000000000005734 164.0
HFD3_k127_3108548_29 Domain of unknown function (DUF3291) - - - 0.0000000000000000000000000000000000000004905 159.0
HFD3_k127_3108548_3 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 532.0
HFD3_k127_3108548_30 Transcriptional regulator, MarR family - - - 0.00000000000000000000000000000000000003004 148.0
HFD3_k127_3108548_31 electron transfer flavoprotein-ubiquinone oxidoreductase - - - 0.0000000000000000000000000000000000001712 159.0
HFD3_k127_3108548_32 PFAM Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000002171 134.0
HFD3_k127_3108548_33 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.000000000000000000000000000008599 128.0
HFD3_k127_3108548_34 CrcB-like protein, Camphor Resistance (CrcB) K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.0000000000000000000000000000685 121.0
HFD3_k127_3108548_35 amine dehydrogenase activity - - - 0.0000000000000000000000000001072 123.0
HFD3_k127_3108548_36 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000006037 126.0
HFD3_k127_3108548_37 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000246 103.0
HFD3_k127_3108548_38 - - - - 0.0000000000000000000005527 105.0
HFD3_k127_3108548_39 helix_turn_helix, cAMP Regulatory protein - - - 0.00000000000000000002683 102.0
HFD3_k127_3108548_4 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009181 514.0
HFD3_k127_3108548_40 Sigma-70 region 2 - - - 0.000000000000001362 84.0
HFD3_k127_3108548_5 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 500.0
HFD3_k127_3108548_6 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K17883 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0010126,GO:0016137,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050627,GO:0050660,GO:0050661,GO:0050662,GO:0051186,GO:0055114,GO:0070402,GO:0071704,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901657 1.8.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007489 482.0
HFD3_k127_3108548_7 Belongs to the N(4) N(6)-methyltransferase family K00571,K00590 - 2.1.1.113,2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 474.0
HFD3_k127_3108548_8 non-haem dioxygenase in morphine synthesis N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004397 472.0
HFD3_k127_3108548_9 Voltage gated chloride channel K03281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 391.0
HFD3_k127_3110128_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 5.853e-291 906.0
HFD3_k127_3110128_1 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000847 559.0
HFD3_k127_3110128_10 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 323.0
HFD3_k127_3110128_11 RNA 2'-O ribose methyltransferase substrate binding K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 317.0
HFD3_k127_3110128_12 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 311.0
HFD3_k127_3110128_13 Pkd domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 298.0
HFD3_k127_3110128_14 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000002616 233.0
HFD3_k127_3110128_15 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 GO:0000287,GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0030145,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000002427 235.0
HFD3_k127_3110128_16 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00991 - 2.7.7.60 0.000000000000000000000000000000000000000000000000000000000000006545 243.0
HFD3_k127_3110128_17 Putative bacterial sensory transduction regulator - - - 0.0000000000000000000000000000000000000000000001914 187.0
HFD3_k127_3110128_19 Diguanylate cyclase - - - 0.000000000000000006707 97.0
HFD3_k127_3110128_2 Glycosyl transferase 4-like domain K15521 - 2.4.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 515.0
HFD3_k127_3110128_20 - - - - 0.000000000005728 76.0
HFD3_k127_3110128_21 Substrate binding domain of ABC-type glycine betaine transport system K05845 - - 0.00000000001806 75.0
HFD3_k127_3110128_22 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.000000004479 67.0
HFD3_k127_3110128_3 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 492.0
HFD3_k127_3110128_4 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 494.0
HFD3_k127_3110128_5 Delta-aminolevulinic acid dehydratase K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 428.0
HFD3_k127_3110128_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 433.0
HFD3_k127_3110128_7 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007503 416.0
HFD3_k127_3110128_8 transferase activity, transferring alkyl or aryl (other than methyl) groups K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 354.0
HFD3_k127_3110128_9 transcriptional regulator K01420,K10914,K21561,K21564 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 330.0
HFD3_k127_3133706_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1257.0
HFD3_k127_3133706_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 3.222e-197 623.0
HFD3_k127_3133706_10 ADP-glyceromanno-heptose 6-epimerase activity K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007634 370.0
HFD3_k127_3133706_11 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K01055 - 3.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 373.0
HFD3_k127_3133706_12 replication factor c K02341,K02343,K09384 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005285 335.0
HFD3_k127_3133706_13 Pfam:Zinicin_2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000142 289.0
HFD3_k127_3133706_14 type II secretion system protein E K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002527 288.0
HFD3_k127_3133706_15 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002769 286.0
HFD3_k127_3133706_16 Elongation factor SelB, winged helix K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002315 270.0
HFD3_k127_3133706_17 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000245 275.0
HFD3_k127_3133706_18 Belongs to the NUDIX hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006188 273.0
HFD3_k127_3133706_19 spore germination - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005975 261.0
HFD3_k127_3133706_2 MMPL family K06994 - - 7.671e-195 633.0
HFD3_k127_3133706_20 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000001611 232.0
HFD3_k127_3133706_21 Inosine-uridine preferring nucleoside hydrolase K01239 - 3.2.2.1 0.000000000000000000000000000000000000000000000000000000000000001481 236.0
HFD3_k127_3133706_22 Pyridoxamine 5-phosphate - - - 0.0000000000000000000000000000000000000000000000000000000000001465 214.0
HFD3_k127_3133706_23 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000004 216.0
HFD3_k127_3133706_24 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000001149 189.0
HFD3_k127_3133706_26 DNA-binding transcription factor activity K04096,K20421 - 2.1.1.303 0.0000000000000000000000000000000000002574 147.0
HFD3_k127_3133706_27 - - - - 0.000000000000000000000000000007768 128.0
HFD3_k127_3133706_28 Type II secretion system (T2SS), protein F K12511 - - 0.00000000000000000000000000002452 130.0
HFD3_k127_3133706_29 Putative zinc-finger - - - 0.000000000000000000004666 94.0
HFD3_k127_3133706_3 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 6.317e-194 611.0
HFD3_k127_3133706_30 PFAM TadE family protein - - - 0.000000000000000003612 88.0
HFD3_k127_3133706_31 Cupin 2, conserved barrel domain protein - - - 0.000000000000002271 89.0
HFD3_k127_3133706_32 Belongs to the anti-sigma-factor antagonist family - - - 0.0000003609 56.0
HFD3_k127_3133706_33 Type ii secretion system K12510 - - 0.0000007886 62.0
HFD3_k127_3133706_34 - - - - 0.000186 48.0
HFD3_k127_3133706_35 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins K15532 - 3.2.1.172 0.0004386 52.0
HFD3_k127_3133706_36 Helix-turn-helix domain - - - 0.0005687 47.0
HFD3_k127_3133706_4 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 464.0
HFD3_k127_3133706_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 420.0
HFD3_k127_3133706_6 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007272 408.0
HFD3_k127_3133706_7 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 436.0
HFD3_k127_3133706_8 Scramblase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005829 397.0
HFD3_k127_3133706_9 non-haem dioxygenase in morphine synthesis N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 381.0
HFD3_k127_3239121_0 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 1.039e-217 692.0
HFD3_k127_3239121_1 Glycosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 477.0
HFD3_k127_3239121_10 hemerythrin HHE cation binding domain - - - 0.00000000000000000000000002663 120.0
HFD3_k127_3239121_11 - - - - 0.000000000000000000004853 98.0
HFD3_k127_3239121_12 Protein of unknown function DUF72 - - - 0.00000000000000000000806 95.0
HFD3_k127_3239121_14 antisigma factor binding K04749 - - 0.0000000001135 68.0
HFD3_k127_3239121_15 antisigma factor binding - - - 0.00000009015 61.0
HFD3_k127_3239121_16 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000002019 62.0
HFD3_k127_3239121_17 Histidine kinase-like ATPase domain - - - 0.000001043 57.0
HFD3_k127_3239121_2 Short-chain dehydrogenase reductase sdr K14633 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007145 331.0
HFD3_k127_3239121_3 Rubrerythrin K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000009588 259.0
HFD3_k127_3239121_4 Domain of unknown function (DUF4130 K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000001593 210.0
HFD3_k127_3239121_5 COG3569 Topoisomerase IB K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000004964 190.0
HFD3_k127_3239121_6 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000005091 183.0
HFD3_k127_3239121_7 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template - - - 0.000000000000000000000000000000000000000008723 159.0
HFD3_k127_3239121_8 MEDS: MEthanogen/methylotroph, DcmR Sensory domain - - - 0.00000000000000000000000000000000000000001889 165.0
HFD3_k127_3239121_9 Cbs domain - - - 0.000000000000000000000000000000000000007911 149.0
HFD3_k127_3257264_0 Biotin carboxylase C-terminal domain K11263 - 6.3.4.14,6.4.1.2,6.4.1.3 5.418e-270 874.0
HFD3_k127_3257264_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 1.158e-220 691.0
HFD3_k127_3257264_10 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.00000000000000000000000000000000000008063 161.0
HFD3_k127_3257264_11 Histidine kinase - - - 0.00000000000000004215 87.0
HFD3_k127_3257264_2 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000992 504.0
HFD3_k127_3257264_3 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009228 478.0
HFD3_k127_3257264_4 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006795 446.0
HFD3_k127_3257264_5 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901576 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 432.0
HFD3_k127_3257264_6 Cell envelope-related transcriptional attenuator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 320.0
HFD3_k127_3257264_7 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 294.0
HFD3_k127_3257264_8 D-alanyl-D-alanine carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 298.0
HFD3_k127_3257264_9 dTDP-4-dehydrorhamnose 3,5-epimerase activity K00067,K01710,K01790 - 1.1.1.133,4.2.1.46,5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000006474 268.0
HFD3_k127_331629_0 Belongs to the TPP enzyme family K03336 - 3.7.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 581.0
HFD3_k127_331629_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009652 512.0
HFD3_k127_331629_2 KduI/IolB family K03337 - 5.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003836 406.0
HFD3_k127_331629_3 pfkB family carbohydrate kinase K03338 - 2.7.1.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000506 358.0
HFD3_k127_331629_4 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 357.0
HFD3_k127_331629_5 deoxyribose-phosphate aldolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006679 310.0
HFD3_k127_331629_6 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000000000009267 204.0
HFD3_k127_3349090_0 Baseplate J-like protein - - - 7.412e-236 745.0
HFD3_k127_3349090_1 Phage late control gene D protein (GPD) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 567.0
HFD3_k127_3349090_10 Zinc finger domain - - - 0.0000000000000000000000000000000000000000000000000002911 206.0
HFD3_k127_3349090_11 Gene 25-like lysozyme K06903 - - 0.0000000000000000000000000000000000000000000000002221 181.0
HFD3_k127_3349090_13 Domain of unknown function (DUF4280) - - - 0.00000000000000000000000000000000000000000000005396 173.0
HFD3_k127_3349090_14 positive regulation of growth rate - - - 0.00000000000000000000000000000000000000004849 160.0
HFD3_k127_3349090_15 phage tail protein - - - 0.0000000000000000000000000002526 126.0
HFD3_k127_3349090_2 Thi4 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 527.0
HFD3_k127_3349090_3 Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005003 479.0
HFD3_k127_3349090_4 PFAM transcriptional regulator domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006556 390.0
HFD3_k127_3349090_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008923 366.0
HFD3_k127_3349090_6 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 351.0
HFD3_k127_3349090_7 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 311.0
HFD3_k127_3349090_8 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 302.0
HFD3_k127_3349090_9 Phage tail protein (Tail_P2_I) - - - 0.00000000000000000000000000000000000000000000000000000000000001514 225.0
HFD3_k127_3404117_0 PFAM ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 312.0
HFD3_k127_3404117_1 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 314.0
HFD3_k127_3404117_10 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.00000006877 57.0
HFD3_k127_3404117_11 helix_turn_helix, Lux Regulon - - - 0.0000001913 62.0
HFD3_k127_3404117_12 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000005539 52.0
HFD3_k127_3404117_13 membrane protein (DUF2078) K08982 - - 0.00000214 54.0
HFD3_k127_3404117_2 His Kinase A (phosphoacceptor) domain K07642 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002895 286.0
HFD3_k127_3404117_3 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001336 272.0
HFD3_k127_3404117_4 PFAM response regulator receiver K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000004362 237.0
HFD3_k127_3404117_5 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000001262 130.0
HFD3_k127_3404117_6 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000008049 69.0
HFD3_k127_3404117_8 Protein of unknown function with PCYCGC motif - - - 0.0000000002053 68.0
HFD3_k127_3404117_9 membrane protein (DUF2078) K08982 - - 0.000000005864 62.0
HFD3_k127_3418410_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688,K18786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.321 0.0 3096.0
HFD3_k127_3418410_1 Peptidoglycan-binding domain 1 protein - - - 0.0 1676.0
HFD3_k127_3418410_10 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005803 584.0
HFD3_k127_3418410_11 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 556.0
HFD3_k127_3418410_12 L-lysine 6-monooxygenase (NADPH-requiring) K07222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 507.0
HFD3_k127_3418410_13 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 503.0
HFD3_k127_3418410_14 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 441.0
HFD3_k127_3418410_15 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 429.0
HFD3_k127_3418410_16 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 386.0
HFD3_k127_3418410_17 alkaline phosphatase K01077,K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 379.0
HFD3_k127_3418410_18 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007088 332.0
HFD3_k127_3418410_19 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007622 256.0
HFD3_k127_3418410_2 Salmonella virulence plasmid 28.1kDa A protein - - - 0.0 1455.0
HFD3_k127_3418410_20 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005898 259.0
HFD3_k127_3418410_21 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003817 245.0
HFD3_k127_3418410_22 FtsX-like permease family K02004 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009405,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0051704,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000006526 243.0
HFD3_k127_3418410_23 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000000000000000000000000008103 229.0
HFD3_k127_3418410_24 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000002996 218.0
HFD3_k127_3418410_25 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000353 208.0
HFD3_k127_3418410_26 Anti-sigma-K factor rskA - - - 0.00000000000000000000000000000000000000000000000000000000719 205.0
HFD3_k127_3418410_27 membrane K13277,K15125,K15539 - - 0.00000000000000000000000000000000000000000000000000000001961 229.0
HFD3_k127_3418410_28 Predicted membrane protein (DUF2231) - - - 0.0000000000000000000000000000000000000000000000000000002827 201.0
HFD3_k127_3418410_29 Flavodoxin domain K00230 - 1.3.5.3 0.0000000000000000000000000000000000000000000000000005591 189.0
HFD3_k127_3418410_3 - - - - 0.0 1206.0
HFD3_k127_3418410_30 Belongs to the TPP enzyme family - - - 0.000000000000000000000000000000000000000000000005753 201.0
HFD3_k127_3418410_31 - - - - 0.0000000000000000000000000000000000000000006042 167.0
HFD3_k127_3418410_32 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000004765 164.0
HFD3_k127_3418410_33 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000226 143.0
HFD3_k127_3418410_34 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000002215 147.0
HFD3_k127_3418410_35 SnoaL-like domain - - - 0.0000000000000000000000000000000004332 135.0
HFD3_k127_3418410_36 Belongs to the globin family K05916 - 1.14.12.17 0.0000000000000000000000000000000007071 142.0
HFD3_k127_3418410_37 regulator of chromosome condensation, RCC1 - - - 0.000000000000000000000000000005772 141.0
HFD3_k127_3418410_38 Secreted repeat of unknown function - - - 0.0000000000000000000000000008415 122.0
HFD3_k127_3418410_39 nitric oxide dioxygenase activity K05916 - 1.14.12.17 0.0000000000000000000000004714 116.0
HFD3_k127_3418410_4 - - - - 0.0 1147.0
HFD3_k127_3418410_40 - - - - 0.0000000000000000000002182 98.0
HFD3_k127_3418410_41 Prokaryotic dksA/traR C4-type zinc finger - - - 0.000000000000000000004687 100.0
HFD3_k127_3418410_42 - - - - 0.00000000000005657 79.0
HFD3_k127_3418410_43 Domain of unknown function (DUF4157) - - - 0.0000000000003311 79.0
HFD3_k127_3418410_44 - - - - 0.00000000005596 66.0
HFD3_k127_3418410_45 - - - - 0.00000002989 65.0
HFD3_k127_3418410_46 Methyltransferase - - - 0.0004316 51.0
HFD3_k127_3418410_5 HD domain - - - 9.545e-217 685.0
HFD3_k127_3418410_6 Adenylyl cyclase class-3 4 guanylyl cyclase - - - 7.823e-209 695.0
HFD3_k127_3418410_7 Phospholipase D Transphosphatidylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 611.0
HFD3_k127_3418410_8 Protein of unknown function (DUF1298) K00635 - 2.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 617.0
HFD3_k127_3418410_9 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 617.0
HFD3_k127_3430211_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 588.0
HFD3_k127_3430211_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 507.0
HFD3_k127_3430211_2 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 353.0
HFD3_k127_3430211_3 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000005642 232.0
HFD3_k127_3430211_4 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000202 202.0
HFD3_k127_3430211_5 FMN binding - - - 0.000000000000000000000000000000000000000000000008557 175.0
HFD3_k127_3444452_0 PFAM regulatory protein ArsR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 398.0
HFD3_k127_3444452_1 Methylenetetrahydrofolate reductase K00297 GO:0003674,GO:0003824,GO:0004489,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002606 285.0
HFD3_k127_3444452_2 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.000000000000000000000000000000000000000000000000000006055 196.0
HFD3_k127_3444452_3 Belongs to the thiolase family - - - 0.000000000000000000000000000000000000000000000000001462 184.0
HFD3_k127_3444452_4 Protein tyrosine serine phosphatase K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000000000007649 190.0
HFD3_k127_3459775_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.898e-296 925.0
HFD3_k127_3459775_1 Glycosyltransferase like family 2 - - - 2.767e-286 914.0
HFD3_k127_3459775_2 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 541.0
HFD3_k127_3459775_3 polysaccharide biosynthetic process K01992 GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0008150,GO:0009987,GO:0044764,GO:0046812,GO:0051704 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003625 528.0
HFD3_k127_3459775_5 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000001579 195.0
HFD3_k127_3459775_6 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000002068 142.0
HFD3_k127_3459775_7 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000001782 141.0
HFD3_k127_3476065_0 Pyridoxal-phosphate dependent enzyme K21148 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 536.0
HFD3_k127_3476065_1 protoporphyrinogen oxidase activity K01854 - 5.4.99.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 496.0
HFD3_k127_3476065_10 EamA-like transporter family - - - 0.00000000000000000000000000002465 133.0
HFD3_k127_3476065_11 overlaps another CDS with the same product name - - - 0.0000000000000000000000000004101 129.0
HFD3_k127_3476065_12 - - - - 0.000000000000000000000000003905 121.0
HFD3_k127_3476065_13 cellulose binding - - - 0.000000000000007514 87.0
HFD3_k127_3476065_14 dioxygenase activity - - - 0.000000000805 70.0
HFD3_k127_3476065_2 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 381.0
HFD3_k127_3476065_3 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001004 295.0
HFD3_k127_3476065_4 PFAM glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003928 277.0
HFD3_k127_3476065_5 Sortase family K07284 - 3.4.22.70 0.0000000000000000000000000000000000000000000000000000000000000000005967 249.0
HFD3_k127_3476065_6 PFAM transferase hexapeptide repeat containing protein K00661 - 2.3.1.79 0.000000000000000000000000000000000000004859 152.0
HFD3_k127_3476065_7 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000006262 158.0
HFD3_k127_3476065_8 PFAM aldo keto reductase - - - 0.000000000000000000000000000000136 138.0
HFD3_k127_3476065_9 COG2303 Choline dehydrogenase and related flavoproteins - - - 0.0000000000000000000000000000003086 141.0
HFD3_k127_349489_0 Type ii secretion system protein e K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 535.0
HFD3_k127_349489_1 Peptidase family S41 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008898 518.0
HFD3_k127_349489_10 LysM domain K12204 - - 0.000000000000000000000000000000000000006908 160.0
HFD3_k127_349489_16 TadE-like protein - - - 0.000002243 57.0
HFD3_k127_349489_2 ethanolamine kinase activity K07251 - 2.7.1.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 318.0
HFD3_k127_349489_3 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 316.0
HFD3_k127_349489_4 PFAM methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000001892 226.0
HFD3_k127_349489_5 Type ii secretion system - - - 0.00000000000000000000000000000000000000000000000000000000002234 219.0
HFD3_k127_349489_6 Type II secretion system (T2SS), protein F K12511 - - 0.00000000000000000000000000000000000000000000000000001099 210.0
HFD3_k127_349489_7 PFAM Peptidoglycan-binding LysM - - - 0.000000000000000000000000000000000000000000000001267 198.0
HFD3_k127_349489_8 molybdenum ion binding K07140 - - 0.00000000000000000000000000000000000000000000001732 180.0
HFD3_k127_349489_9 SAF - - - 0.000000000000000000000000000000000000002781 155.0
HFD3_k127_353395_0 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 630.0
HFD3_k127_353395_1 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000069 516.0
HFD3_k127_353395_10 PFAM Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000001973 203.0
HFD3_k127_353395_11 Fungal family of unknown function (DUF1776) - - - 0.00000000000000000000000000000000000000000000000000000003229 207.0
HFD3_k127_353395_12 glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.0000000000000000000000000000000000000000006698 161.0
HFD3_k127_353395_13 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000001197 139.0
HFD3_k127_353395_14 branched-chain amino acid permease (azaleucine resistance) - - - 0.0000000000000000000002038 106.0
HFD3_k127_353395_15 GYD domain - - - 0.000000000009522 69.0
HFD3_k127_353395_16 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000002491 55.0
HFD3_k127_353395_2 beta-1,4-mannooligosaccharide phosphorylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 477.0
HFD3_k127_353395_3 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 400.0
HFD3_k127_353395_4 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 383.0
HFD3_k127_353395_5 Thioesterase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006258 319.0
HFD3_k127_353395_6 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002288 277.0
HFD3_k127_353395_7 MMPL family K06994 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002098 270.0
HFD3_k127_353395_8 pyridoxamine 5-phosphate - - - 0.000000000000000000000000000000000000000000000000000000000000002938 221.0
HFD3_k127_353395_9 Evidence Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02003,K05685 - - 0.0000000000000000000000000000000000000000000000000000000002983 211.0
HFD3_k127_3586689_0 B3/4 domain K01890 - 6.1.1.20 1.321e-306 957.0
HFD3_k127_3586689_1 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 578.0
HFD3_k127_3586689_10 Belongs to the UPF0301 (AlgH) family K07735 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000005207 224.0
HFD3_k127_3586689_11 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000001225 210.0
HFD3_k127_3586689_12 Regulates arginine biosynthesis genes K03402 - - 0.0000000000000000000000000000000000000000000000000000000001744 217.0
HFD3_k127_3586689_13 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000001621 209.0
HFD3_k127_3586689_14 SpoU rRNA Methylase family K03437 - - 0.000000000000000000000000000000000000000000000000000001421 210.0
HFD3_k127_3586689_15 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000001015 173.0
HFD3_k127_3586689_16 Methylpurine-DNA glycosylase (MPG) K03652 - 3.2.2.21 0.000000000000000000000000000000000000001954 154.0
HFD3_k127_3586689_17 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000005136 94.0
HFD3_k127_3586689_2 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 531.0
HFD3_k127_3586689_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008843 428.0
HFD3_k127_3586689_4 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 420.0
HFD3_k127_3586689_5 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 427.0
HFD3_k127_3586689_6 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 404.0
HFD3_k127_3586689_7 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 383.0
HFD3_k127_3586689_8 Protein of unknown function (DUF664) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 302.0
HFD3_k127_3586689_9 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002541 280.0
HFD3_k127_3650164_0 PFAM Type II secretion system protein E K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 537.0
HFD3_k127_3650164_1 Xaa-Pro aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 504.0
HFD3_k127_3650164_10 Pilus assembly protein K02279 - - 0.0000000000000000000000000007117 123.0
HFD3_k127_3650164_11 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000002377 104.0
HFD3_k127_3650164_12 Putative Flp pilus-assembly TadE/G-like - - - 0.0000000000001639 82.0
HFD3_k127_3650164_13 HNH nucleases - - - 0.00000004517 63.0
HFD3_k127_3650164_14 Peptidase A24A, prepilin type IV K02654 - 3.4.23.43 0.0000009727 54.0
HFD3_k127_3650164_16 PFAM HNH endonuclease - - - 0.000184 51.0
HFD3_k127_3650164_2 Pfam Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 448.0
HFD3_k127_3650164_3 F420-dependent oxidoreductase, Rv1855c family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000667 273.0
HFD3_k127_3650164_4 Fatty acid desaturase K00508 - 1.14.19.3 0.00000000000000000000000000000000000000000000000000000000000000000000001052 255.0
HFD3_k127_3650164_5 cell adhesion involved in biofilm formation K13735,K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000001026 261.0
HFD3_k127_3650164_6 Type ii secretion system K12510 - - 0.0000000000000000000000000000000000000000000000000000000000007276 233.0
HFD3_k127_3650164_7 Pilus assembly protein K02282 - - 0.00000000000000000000000000000000000000000000000002961 193.0
HFD3_k127_3650164_8 Type ii secretion system K12511 - - 0.00000000000000000000000000000000000000000003565 172.0
HFD3_k127_3650164_9 acetyltransferase - - - 0.00000000000000000000000000000000306 135.0
HFD3_k127_3721286_0 glycoside hydrolase 15-related K01178 - 3.2.1.3 0.0 1380.0
HFD3_k127_3721286_1 ATPase P-type (Transporting), HAD superfamily, subfamily IC K01535,K01537 - 3.6.3.6,3.6.3.8 1.301e-309 981.0
HFD3_k127_3721286_10 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 411.0
HFD3_k127_3721286_11 Branched-chain amino acid transport system / permease component K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 410.0
HFD3_k127_3721286_12 Periplasmic binding protein domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 367.0
HFD3_k127_3721286_13 Protein of unknown function (DUF1326) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 355.0
HFD3_k127_3721286_14 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 355.0
HFD3_k127_3721286_15 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 349.0
HFD3_k127_3721286_16 acetyltransferase component of pyruvate dehydrogenase complex K00627,K00658 - 2.3.1.12,2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006822 355.0
HFD3_k127_3721286_17 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 355.0
HFD3_k127_3721286_18 ABC-type polysaccharide polyol phosphate transport system, ATPase component K09691 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 352.0
HFD3_k127_3721286_19 amidohydrolase K07046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 297.0
HFD3_k127_3721286_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 3.935e-229 726.0
HFD3_k127_3721286_20 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005857 291.0
HFD3_k127_3721286_21 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 289.0
HFD3_k127_3721286_22 ABC-2 type transporter K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001618 285.0
HFD3_k127_3721286_23 GCN5 family acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003022 285.0
HFD3_k127_3721286_24 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002202 262.0
HFD3_k127_3721286_25 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002052 252.0
HFD3_k127_3721286_26 FCD K05799 - - 0.00000000000000000000000000000000000000000000000000000000000000000004437 239.0
HFD3_k127_3721286_27 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000006681 236.0
HFD3_k127_3721286_28 TrkA-N domain K03499 - - 0.00000000000000000000000000000000000000000000000000000000000000001439 243.0
HFD3_k127_3721286_29 Putative NAD(P)-binding K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000006558 229.0
HFD3_k127_3721286_3 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 8.086e-205 651.0
HFD3_k127_3721286_30 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000006975 242.0
HFD3_k127_3721286_31 cell adhesion involved in biofilm formation K13735,K20276 - - 0.0000000000000000000000000000000000000000000000000000000000006667 239.0
HFD3_k127_3721286_32 Belongs to the glycosyl hydrolase 13 family K01200 - 3.2.1.41 0.0000000000000000000000000000000000000000000000000000000008738 231.0
HFD3_k127_3721286_33 Haemolysin-III related K11068 - - 0.000000000000000000000000000000000000000000000002498 184.0
HFD3_k127_3721286_34 CoA binding domain K06929 - - 0.000000000000000000000000000000000000000000000005331 193.0
HFD3_k127_3721286_35 COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes - - - 0.00000000000000000000000000000000000000000000004106 182.0
HFD3_k127_3721286_36 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000004438 142.0
HFD3_k127_3721286_37 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000005294 139.0
HFD3_k127_3721286_38 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000006271 128.0
HFD3_k127_3721286_39 Dimerisation domain - - - 0.00000000000000000001881 106.0
HFD3_k127_3721286_4 mandelate racemase muconate lactonizing K18334 - 4.2.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009255 581.0
HFD3_k127_3721286_40 Protein of unknown function (DUF861) - - - 0.0000000000000000002591 97.0
HFD3_k127_3721286_41 Protein of unknown function (DUF664) - - - 0.00000000000000001368 86.0
HFD3_k127_3721286_42 Activator of Hsp90 ATPase 1 family protein - - - 0.0000000000000003432 87.0
HFD3_k127_3721286_44 helix_turn_helix, mercury resistance K22491 - - 0.0000000009378 70.0
HFD3_k127_3721286_45 - - - - 0.000000001334 58.0
HFD3_k127_3721286_46 Phosphopantetheine attachment site - - - 0.000000001376 63.0
HFD3_k127_3721286_47 D-alanyl-D-alanine carboxypeptidase - - - 0.0000005073 61.0
HFD3_k127_3721286_48 Transposase IS116/IS110/IS902 family - - - 0.000007753 57.0
HFD3_k127_3721286_49 antisigma factor binding K06378 - - 0.000007932 53.0
HFD3_k127_3721286_5 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003859 505.0
HFD3_k127_3721286_6 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009644 486.0
HFD3_k127_3721286_7 Circadian clock protein KaiC K08482 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 486.0
HFD3_k127_3721286_8 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009076 459.0
HFD3_k127_3721286_9 DEAD DEAH box helicase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009322 446.0
HFD3_k127_3721797_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1410.0
HFD3_k127_3721797_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 2.585e-317 979.0
HFD3_k127_3721797_10 Rieske 2Fe-2S K00499 - 1.14.15.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009388 548.0
HFD3_k127_3721797_11 AMP-binding enzyme C-terminal domain K00666,K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 531.0
HFD3_k127_3721797_12 F420-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006934 536.0
HFD3_k127_3721797_13 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 510.0
HFD3_k127_3721797_14 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 469.0
HFD3_k127_3721797_15 Protein of unknown function (DUF1298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 459.0
HFD3_k127_3721797_16 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 434.0
HFD3_k127_3721797_17 synthase K00697,K16055 GO:0003674,GO:0003824,GO:0003825,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0030312,GO:0033554,GO:0034637,GO:0035251,GO:0040007,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046527,GO:0046872,GO:0046914,GO:0047260,GO:0050896,GO:0051716,GO:0070413,GO:0071704,GO:0071944,GO:1901576 2.4.1.15,2.4.1.347,3.1.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 421.0
HFD3_k127_3721797_18 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000745 392.0
HFD3_k127_3721797_19 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 420.0
HFD3_k127_3721797_2 PFAM AMP-dependent synthetase and ligase K00666,K01909 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008922,GO:0009058,GO:0009987,GO:0015645,GO:0016020,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016874,GO:0016877,GO:0016878,GO:0017076,GO:0019752,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044464,GO:0046394,GO:0051704,GO:0070566,GO:0071704,GO:0071944,GO:0072330,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 6.2.1.20 2.643e-260 859.0
HFD3_k127_3721797_20 ComEC Rec2-related protein K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 396.0
HFD3_k127_3721797_21 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 398.0
HFD3_k127_3721797_22 NADH ubiquinone oxidoreductase, 20 Kd subunit K18007 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008195 383.0
HFD3_k127_3721797_23 Protein of unknown function (DUF1298) K00635 - 2.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 386.0
HFD3_k127_3721797_24 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 379.0
HFD3_k127_3721797_25 dna polymerase III delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 369.0
HFD3_k127_3721797_26 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 351.0
HFD3_k127_3721797_27 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 350.0
HFD3_k127_3721797_28 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 332.0
HFD3_k127_3721797_29 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 329.0
HFD3_k127_3721797_3 N-terminal domain of (some) glycogen debranching enzymes - - - 1.845e-255 808.0
HFD3_k127_3721797_30 Oxidoreductase NAD-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008806 310.0
HFD3_k127_3721797_31 Tetratricopeptide repeat K05838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 309.0
HFD3_k127_3721797_32 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000098 283.0
HFD3_k127_3721797_33 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001309 281.0
HFD3_k127_3721797_34 PAC2 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001445 296.0
HFD3_k127_3721797_35 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001912 274.0
HFD3_k127_3721797_36 Protein of unknown function (DUF664) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004591 258.0
HFD3_k127_3721797_37 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005132 256.0
HFD3_k127_3721797_38 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005656 272.0
HFD3_k127_3721797_39 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000007397 234.0
HFD3_k127_3721797_4 PFAM AMP-dependent synthetase and ligase K00666 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051087 - 1.181e-218 692.0
HFD3_k127_3721797_40 ABC-type branched-chain amino acid transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000001547 255.0
HFD3_k127_3721797_41 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000001043 232.0
HFD3_k127_3721797_42 - - - - 0.0000000000000000000000000000000000000000000000000002757 202.0
HFD3_k127_3721797_43 - - - - 0.000000000000000000000000000000000000000000000000004495 187.0
HFD3_k127_3721797_44 Domain of unknown function (DUF1989) K09967 - - 0.0000000000000000000000000000000000000000000000001647 186.0
HFD3_k127_3721797_45 lactoylglutathione lyase activity K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000009747 188.0
HFD3_k127_3721797_46 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000001257 179.0
HFD3_k127_3721797_47 Competence protein ComEA K02237 - - 0.000000000000000000000000000000000000000000000003161 181.0
HFD3_k127_3721797_48 ABC-type antimicrobial peptide transport system, ATPase component K02003,K05685 - - 0.000000000000000000000000000000000000000000001629 173.0
HFD3_k127_3721797_49 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.00000000000000000000000000000000000000000005548 167.0
HFD3_k127_3721797_5 MMPL family K07003 - - 3.321e-194 661.0
HFD3_k127_3721797_50 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000002191 163.0
HFD3_k127_3721797_51 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000001398 152.0
HFD3_k127_3721797_52 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000003338 158.0
HFD3_k127_3721797_53 Transcriptional regulator - - - 0.00000000000000000000000000000000000421 154.0
HFD3_k127_3721797_54 - - - - 0.000000000000000000000000000000005964 129.0
HFD3_k127_3721797_55 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000008219 145.0
HFD3_k127_3721797_56 polysaccharide deacetylase K15531 - 3.2.1.156 0.000000000000000000000000000006431 137.0
HFD3_k127_3721797_57 Major facilitator superfamily - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000003821 133.0
HFD3_k127_3721797_58 PFAM Glyoxalase Bleomycin resistance protein Dioxygenase superfamily K08234 - - 0.00000000000000000000000000005855 132.0
HFD3_k127_3721797_59 F420-dependent oxidoreductase, Rv1855c family - - - 0.0000000000000000000000000003248 117.0
HFD3_k127_3721797_6 ABC1 family K03688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000868 627.0
HFD3_k127_3721797_60 - - - - 0.000000000000000000000000004595 127.0
HFD3_k127_3721797_61 Hydrogenase maturation protease K03605 - - 0.0000000000000000000001077 109.0
HFD3_k127_3721797_63 Binds directly to 16S ribosomal RNA K02968 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000005552 83.0
HFD3_k127_3721797_65 - - - - 0.00000000000003672 83.0
HFD3_k127_3721797_66 - - - - 0.0000000000001103 84.0
HFD3_k127_3721797_67 Cation efflux family - - - 0.000000001192 67.0
HFD3_k127_3721797_69 Hydrolase - - - 0.0003208 52.0
HFD3_k127_3721797_7 aspartate--ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006853 593.0
HFD3_k127_3721797_70 - - - - 0.0008789 47.0
HFD3_k127_3721797_8 N-terminal domain of (some) glycogen debranching enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007 611.0
HFD3_k127_3721797_9 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 571.0
HFD3_k127_3726836_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 2.43e-265 824.0
HFD3_k127_3726836_1 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004713 396.0
HFD3_k127_3726836_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 341.0
HFD3_k127_3726836_3 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004666 271.0
HFD3_k127_3726836_4 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000001565 225.0
HFD3_k127_3726836_5 - - - - 0.0000000000000000000000001835 111.0
HFD3_k127_3726836_6 Acetyltransferase (GNAT) family - - - 0.000000000000000000000002561 113.0
HFD3_k127_3757327_0 protein secretion K20276,K21449 - - 4.648e-220 739.0
HFD3_k127_3757327_1 associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 455.0
HFD3_k127_3757327_2 DNA segregation ATPase FtsK SpoIIIE and related K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008614 405.0
HFD3_k127_3757327_3 Peptidase family M41 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 304.0
HFD3_k127_3757327_4 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 308.0
HFD3_k127_3757327_5 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001877 279.0
HFD3_k127_3757327_6 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.000000000000000000000000000000000000000000000000000000000000000000003644 246.0
HFD3_k127_388718_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 464.0
HFD3_k127_388718_1 Nucleotidyl transferase K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 410.0
HFD3_k127_388718_2 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 382.0
HFD3_k127_388718_3 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 326.0
HFD3_k127_388718_4 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 310.0
HFD3_k127_388718_5 - - - - 0.00000000000000000000000000000000000000000166 167.0
HFD3_k127_3889236_0 Aldehyde dehydrogenase K00128,K00130 - 1.2.1.3,1.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000852 509.0
HFD3_k127_3889236_1 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009653 312.0
HFD3_k127_3889236_2 dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004063 276.0
HFD3_k127_3889236_3 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002989 265.0
HFD3_k127_3889236_4 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000001036 229.0
HFD3_k127_3919592_0 Uncharacterized protein family (UPF0051) K09014 - - 2.469e-243 757.0
HFD3_k127_3919592_1 Oligopeptidase b K01354 - 3.4.21.83 6.873e-210 674.0
HFD3_k127_3919592_10 Family of unknown function (DUF5317) - - - 0.00000000000000000000000000000000000000008221 157.0
HFD3_k127_3919592_11 electron transfer activity K05337 GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114 - 0.0000000000000000000000000000015 126.0
HFD3_k127_3919592_12 Rieske-like [2Fe-2S] domain K05710 - - 0.000000000000000000000005105 116.0
HFD3_k127_3919592_13 Methylamine utilisation protein MauE - - - 0.00000000000000000000006257 102.0
HFD3_k127_3919592_14 Short C-terminal domain K08982 - - 0.0002776 49.0
HFD3_k127_3919592_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 9.479e-199 625.0
HFD3_k127_3919592_3 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006526 586.0
HFD3_k127_3919592_4 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 345.0
HFD3_k127_3919592_5 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001398 251.0
HFD3_k127_3919592_6 Aminoacyl-tRNA editing domain - - - 0.0000000000000000000000000000000000000000000000000000000000003647 214.0
HFD3_k127_3919592_7 NifU-like N terminal domain K04488 - - 0.00000000000000000000000000000000000000000000000000000000001922 209.0
HFD3_k127_3919592_8 FeS assembly protein SufD K07033,K09015 GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0040007,GO:0043207,GO:0044085,GO:0044237,GO:0044403,GO:0044419,GO:0050896,GO:0051186,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071840,GO:0075136 - 0.00000000000000000000000000000000000000000000000000004373 201.0
HFD3_k127_3919592_9 - - - - 0.000000000000000000000000000000000000000002166 159.0
HFD3_k127_3940082_0 Acetyl-CoA carboxylase, central region - - - 0.0 1383.0
HFD3_k127_3940082_1 Ketoacyl-synthetase C-terminal extension - - - 7.952e-274 869.0
HFD3_k127_3940082_2 unsaturated fatty acid biosynthetic process K10255 - 1.14.19.23,1.14.19.45 0.00000000000000000000000000000000000000000000000000000000000000000001221 246.0
HFD3_k127_3940082_3 PFAM Activator of Hsp90 ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000006103 219.0
HFD3_k127_3940082_4 helix_turn_helix, Arsenical Resistance Operon Repressor - GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043254,GO:0044087,GO:0044212,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000008356 127.0
HFD3_k127_3950929_0 Domain of unknown function (DUF427) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005852 292.0
HFD3_k127_3950929_1 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007925 259.0
HFD3_k127_3950929_2 alginic acid biosynthetic process K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004959 271.0
HFD3_k127_3950929_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000004316 216.0
HFD3_k127_3950929_4 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000244 173.0
HFD3_k127_3950929_5 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000008149 184.0
HFD3_k127_3950929_6 ABC transporter K02003 - - 0.00000000000000000000000000000000005301 137.0
HFD3_k127_3950929_7 Glutathione-dependent formaldehyde-activating - - - 0.0000000000000000000000000002946 116.0
HFD3_k127_3950929_8 Transport permease protein K01992 - - 0.000000000000004133 86.0
HFD3_k127_404330_0 WD40-like Beta Propeller Repeat - - - 2.894e-250 801.0
HFD3_k127_404330_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 2.142e-235 743.0
HFD3_k127_404330_10 peptidase C26 K01658,K07010 - 4.1.3.27 0.0000000000000000000000000000000000000000002018 168.0
HFD3_k127_404330_11 positive regulation of acetylcholine metabolic process K06910 - - 0.000000000000000000000000001332 122.0
HFD3_k127_404330_12 Protein of unknown function, DUF488 - - - 0.00000000000000000000000002188 113.0
HFD3_k127_404330_14 - - - - 0.0000000000000000001191 102.0
HFD3_k127_404330_15 - - - - 0.0000000000000000003017 100.0
HFD3_k127_404330_18 oxidoreductase - - - 0.0008761 50.0
HFD3_k127_404330_2 GlcNAc-PI de-N-acetylase K18455 - 3.5.1.115 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 460.0
HFD3_k127_404330_3 diacylglycerol O-acyltransferase K00635 GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700 2.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 453.0
HFD3_k127_404330_4 YdjC-like protein K03478 - 3.5.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 415.0
HFD3_k127_404330_5 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 377.0
HFD3_k127_404330_6 NADH pyrophosphatase K03426 - 3.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 339.0
HFD3_k127_404330_7 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 323.0
HFD3_k127_404330_8 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000009854 204.0
HFD3_k127_404330_9 nuclease K01174,K07038 - 3.1.31.1 0.000000000000000000000000000000000000000000000008346 178.0
HFD3_k127_4056445_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 565.0
HFD3_k127_4056445_1 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004067 548.0
HFD3_k127_4056445_10 protein conserved in bacteria K21470 - - 0.0001025 55.0
HFD3_k127_4056445_11 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0008150,GO:0040007 2.7.8.13 0.0006136 53.0
HFD3_k127_4056445_2 Alcohol dehydrogenase groes K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 492.0
HFD3_k127_4056445_3 Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 462.0
HFD3_k127_4056445_4 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 442.0
HFD3_k127_4056445_5 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 405.0
HFD3_k127_4056445_6 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000005784 227.0
HFD3_k127_4056445_7 Activator of hsp90 atpase 1 family protein - - - 0.0000000000000000000000000000000006003 142.0
HFD3_k127_4056445_8 Thioesterase-like superfamily - - - 0.0000000000000000005409 94.0
HFD3_k127_4056445_9 Cell wall hydrolase K01449 - 3.5.1.28 0.00003093 54.0
HFD3_k127_4151923_0 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007542 537.0
HFD3_k127_4151923_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 464.0
HFD3_k127_4151923_2 Domain of unknown function (DUF4262) - - - 0.00000000000000000000000000000000000000000000000000000000000000000004705 234.0
HFD3_k127_4151923_3 Histidine phosphatase superfamily (branch 1) K15634 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000492 223.0
HFD3_k127_4151923_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000003227 223.0
HFD3_k127_4151923_5 SURF1-like protein - GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000003694 203.0
HFD3_k127_4151923_6 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain - - - 0.000000000000000000000000000000000000000000005803 175.0
HFD3_k127_4151923_7 alpha/beta hydrolase fold K00641 - 2.3.1.31 0.0000002848 56.0
HFD3_k127_4154573_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1158.0
HFD3_k127_4154573_1 Amidase K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 540.0
HFD3_k127_4154573_10 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.00000886 48.0
HFD3_k127_4154573_2 GMC oxidoreductase K00108 - 1.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004114 406.0
HFD3_k127_4154573_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000002765 249.0
HFD3_k127_4154573_4 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000331 220.0
HFD3_k127_4154573_5 SnoaL-like polyketide cyclase K15945 - - 0.000000000000000000000000000000000000000000000000008478 185.0
HFD3_k127_4154573_6 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000001798 156.0
HFD3_k127_4154573_7 F420H(2)-dependent quinone reductase - - - 0.00000000000000000000000000000000000001817 149.0
HFD3_k127_4154573_8 Uncharacterized conserved protein (DUF2277) - - - 0.00000000000000000000000000002185 123.0
HFD3_k127_4154573_9 translation elongation factor activity K02358 - - 0.00000008111 53.0
HFD3_k127_4179798_0 Aldehyde dehydrogenase K04072,K15515 - 1.1.1.1,1.2.1.10,1.2.1.81 0.0 1168.0
HFD3_k127_4179798_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 9.253e-269 835.0
HFD3_k127_4179798_2 Belongs to the arginase family K01480 - 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 512.0
HFD3_k127_4179798_3 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 492.0
HFD3_k127_4179798_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006722 447.0
HFD3_k127_4179798_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000001938 216.0
HFD3_k127_4179798_6 FtsX-like permease family - - - 0.000000000000000000000000000005934 138.0
HFD3_k127_4179798_7 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000008 107.0
HFD3_k127_4195301_0 Belongs to the aldehyde dehydrogenase family K00151 - 1.2.1.60 1.006e-215 696.0
HFD3_k127_4195301_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K00446 - 1.13.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 468.0
HFD3_k127_4195301_10 electron transport chain K00347,K03614,K21163 - 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001809 289.0
HFD3_k127_4195301_11 Periplasmic binding protein domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005731 256.0
HFD3_k127_4195301_12 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000004909 257.0
HFD3_k127_4195301_13 import. Responsible for energy coupling to the transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000005888 239.0
HFD3_k127_4195301_14 FCD - - - 0.0000000000000000000000000000000000000000000000000000000005139 213.0
HFD3_k127_4195301_15 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.000000000000000000000000000000000000000000000000000005678 204.0
HFD3_k127_4195301_16 SnoaL-like domain - - - 0.000000000000000000007977 104.0
HFD3_k127_4195301_17 SnoaL-like domain - - - 0.000000001039 66.0
HFD3_k127_4195301_18 - - - - 0.00001389 54.0
HFD3_k127_4195301_19 Ethyl tert-butyl ether degradation EthD - - - 0.00002515 51.0
HFD3_k127_4195301_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 459.0
HFD3_k127_4195301_3 Alcohol dehydrogenase GroES-like domain K00121 - 1.1.1.1,1.1.1.284 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008241 445.0
HFD3_k127_4195301_4 import. Responsible for energy coupling to the transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 438.0
HFD3_k127_4195301_5 Methionine synthase K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 411.0
HFD3_k127_4195301_6 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 359.0
HFD3_k127_4195301_7 SMP-30/Gluconolaconase/LRE-like region K01053,K14274 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 321.0
HFD3_k127_4195301_8 F420-dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 316.0
HFD3_k127_4195301_9 SMP-30/Gluconolaconase/LRE-like region K01053,K14274 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 291.0
HFD3_k127_4231911_0 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006565 309.0
HFD3_k127_4231911_1 endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000002192 179.0
HFD3_k127_4231911_4 Helix-turn-helix domain, rpiR family - - - 0.00000000000000000000000000002268 128.0
HFD3_k127_4231911_6 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.00005155 48.0
HFD3_k127_4240121_0 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000003253 196.0
HFD3_k127_4240121_1 Predicted membrane protein (DUF2142) - - - 0.0000000000000000000000000000000000000000000000002052 196.0
HFD3_k127_4240121_2 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000001631 179.0
HFD3_k127_4240121_3 Glycosyl transferase family 2 - - - 0.000000000000000000000002156 107.0
HFD3_k127_4240121_4 Predicted membrane protein (DUF2142) - - - 0.000000000000001858 86.0
HFD3_k127_4458793_0 Peptidase family M48 K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004233 440.0
HFD3_k127_4458793_1 cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 413.0
HFD3_k127_4458793_2 Glycosyl transferases group 1 K08256 - 2.4.1.345 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 407.0
HFD3_k127_4458793_3 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002079 293.0
HFD3_k127_4458793_4 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002623 259.0
HFD3_k127_4458793_5 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.00000000000000156 81.0
HFD3_k127_4458793_6 - - - - 0.0005938 46.0
HFD3_k127_446027_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 556.0
HFD3_k127_446027_1 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 318.0
HFD3_k127_446027_2 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000559 278.0
HFD3_k127_446027_3 MafB19-like deaminase K01485 - 3.5.4.1 0.000000000000000000000000000000000000000000000000000000004011 205.0
HFD3_k127_446027_4 Antibiotic biosynthesis monooxygenase K06996,K21481 - 1.14.99.57 0.000000000000000000000000000000000002705 141.0
HFD3_k127_446027_5 protein conserved in bacteria - - - 0.00000000000000000001046 92.0
HFD3_k127_446027_6 dehydratase - - - 0.0000000000005154 81.0
HFD3_k127_446027_7 Staphylococcal nuclease homologues K01174,K07038 - 3.1.31.1 0.000000000001011 74.0
HFD3_k127_446027_9 Protein of unknown function (DUF4232) - - - 0.00002442 53.0
HFD3_k127_4483754_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 445.0
HFD3_k127_4483754_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 384.0
HFD3_k127_4483754_2 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 365.0
HFD3_k127_4483754_3 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000000000000000003573 237.0
HFD3_k127_4483754_4 Glucose-regulated metallo-peptidase M90 K09933 - - 0.000000000000000000000000000000000000000000000000000000001743 209.0
HFD3_k127_4483754_5 Domain of unknown function (DUF1932) - - - 0.0000000000000000000000000000000000000000000000000000006331 202.0
HFD3_k127_4483754_6 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000004668 186.0
HFD3_k127_4483754_7 Trehalose synthase - - - 0.0000000000000000000000000000000000000008062 157.0
HFD3_k127_4483754_8 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs - - - 0.0000000000000000000000000000000004863 152.0
HFD3_k127_4483754_9 Colicin V production protein - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009268,GO:0009405,GO:0009628,GO:0010447,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051704,GO:0071944 - 0.000000000000000008607 94.0
HFD3_k127_4485783_0 Protein of unknown function (DUF933) K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 572.0
HFD3_k127_4485783_1 Peptidase S9, prolyl oligopeptidase active site domain protein K01322 - 3.4.21.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 542.0
HFD3_k127_4485783_10 Tetrapyrrole (Corrin/Porphyrin) Methylases K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 300.0
HFD3_k127_4485783_11 TAP-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005677 308.0
HFD3_k127_4485783_12 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.0000000000000000000000000000000000000000000000000000001991 203.0
HFD3_k127_4485783_13 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000001675 188.0
HFD3_k127_4485783_14 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000000000000000007028 154.0
HFD3_k127_4485783_15 translation release factor activity K03265 - - 0.000000000000000000000000000008002 134.0
HFD3_k127_4485783_16 - - - - 0.00000000000000000000000000001341 122.0
HFD3_k127_4485783_17 SnoaL-like domain - - - 0.00000000000000000000000000004739 120.0
HFD3_k127_4485783_18 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.4.21.92 0.0000000000000000000002216 106.0
HFD3_k127_4485783_19 sequence-specific DNA binding K07467 - - 0.0000000000000000006543 89.0
HFD3_k127_4485783_2 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 512.0
HFD3_k127_4485783_20 spore germination - - - 0.000000000000000002648 96.0
HFD3_k127_4485783_21 - - - - 0.00000000000001405 77.0
HFD3_k127_4485783_22 haloacid dehalogenase-like hydrolase - - - 0.000000000003026 70.0
HFD3_k127_4485783_23 N-acetylmuramoyl-L-alanine amidase K01448 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 0.000006894 55.0
HFD3_k127_4485783_24 domain protein - - - 0.0002423 53.0
HFD3_k127_4485783_25 L,D-transpeptidase catalytic domain - - - 0.0005888 50.0
HFD3_k127_4485783_3 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004622 500.0
HFD3_k127_4485783_4 Helix-hairpin-helix domain K04477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 409.0
HFD3_k127_4485783_5 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 391.0
HFD3_k127_4485783_6 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005636 359.0
HFD3_k127_4485783_7 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 322.0
HFD3_k127_4485783_8 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008165 324.0
HFD3_k127_4485783_9 Serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008360,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0040007,GO:0042304,GO:0043085,GO:0043086,GO:0043170,GO:0043388,GO:0043412,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0051055,GO:0051098,GO:0051099,GO:0051101,GO:0051128,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 315.0
HFD3_k127_4517328_0 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 452.0
HFD3_k127_4517328_1 von Willebrand factor type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 334.0
HFD3_k127_4517328_2 Cell envelope-related transcriptional attenuator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001624 287.0
HFD3_k127_4517328_3 PFAM ATPase associated with various cellular activities, AAA_5 K03924 - - 0.000000000000000000000000000000000000000000000000000000000000005436 221.0
HFD3_k127_4517328_4 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000000000000001354 162.0
HFD3_k127_4517328_5 Mechanosensitive ion channel K22044 - - 0.00000000000000000000000000000000000009051 154.0
HFD3_k127_4567575_0 Phage tail sheath C-terminal domain K06907 - - 9.539e-241 761.0
HFD3_k127_4567575_1 cell adhesion involved in biofilm formation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003973 275.0
HFD3_k127_4567575_2 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000002651 231.0
HFD3_k127_4567575_3 - - - - 0.000000000000000000000000000000000000000000000000000001797 194.0
HFD3_k127_4567575_4 T4-like virus tail tube protein gp19 - - - 0.00000000000000000000000000000000000000000000000000007582 189.0
HFD3_k127_4567575_5 Domain of unknown function (DUF4157) - - - 0.0000000000000000000001666 113.0
HFD3_k127_4567575_6 Protein of unknown function (DUF4255) - - - 0.000000000000000000001818 104.0
HFD3_k127_4567575_7 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000003315 103.0
HFD3_k127_4567575_8 - - - - 0.00000000008849 63.0
HFD3_k127_4567575_9 Belongs to the peptidase S8 family - - - 0.000000002402 71.0
HFD3_k127_4587164_0 Domain of unknown function (DUF3367) K16648 - - 0.0 1133.0
HFD3_k127_4587164_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 3.738e-286 885.0
HFD3_k127_4587164_10 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008855 443.0
HFD3_k127_4587164_11 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 458.0
HFD3_k127_4587164_12 Phage integrase, N-terminal SAM-like domain K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009225 413.0
HFD3_k127_4587164_13 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 399.0
HFD3_k127_4587164_14 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 399.0
HFD3_k127_4587164_15 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 368.0
HFD3_k127_4587164_16 RNA pseudouridylate synthase K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004726 335.0
HFD3_k127_4587164_17 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 334.0
HFD3_k127_4587164_18 integral membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004348 335.0
HFD3_k127_4587164_19 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 327.0
HFD3_k127_4587164_2 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 3.679e-239 766.0
HFD3_k127_4587164_20 UbiA prenyltransferase family K14136 - 2.4.2.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 324.0
HFD3_k127_4587164_21 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 295.0
HFD3_k127_4587164_22 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007887 288.0
HFD3_k127_4587164_23 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001111 295.0
HFD3_k127_4587164_24 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009821 289.0
HFD3_k127_4587164_25 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009557 269.0
HFD3_k127_4587164_26 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000251 260.0
HFD3_k127_4587164_27 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005686 282.0
HFD3_k127_4587164_28 PFAM short chain dehydrogenase K16652 GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010383,GO:0016020,GO:0016051,GO:0031221,GO:0033692,GO:0034637,GO:0034645,GO:0035884,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0070589,GO:0070592,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901576 1.1.1.333 0.000000000000000000000000000000000000000000000000000000000000000000007685 252.0
HFD3_k127_4587164_29 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000004722 207.0
HFD3_k127_4587164_3 transferase activity, transferring acyl groups other than amino-acyl groups K13687 GO:0008150,GO:0040007 - 9.346e-205 686.0
HFD3_k127_4587164_30 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000003132 198.0
HFD3_k127_4587164_31 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000004721 191.0
HFD3_k127_4587164_32 Methyltransferase type 12 - - - 0.0000000000000000000000000000000000000000002214 167.0
HFD3_k127_4587164_33 AI-2E family transporter - - - 0.000000000000000000000000000000000000463 161.0
HFD3_k127_4587164_35 lipolytic protein G-D-S-L family - - - 0.000000000000000000000007387 118.0
HFD3_k127_4587164_36 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K04750 - - 0.000000000000000000001009 102.0
HFD3_k127_4587164_38 Acyltransferase family - - - 0.0000000000000000236 98.0
HFD3_k127_4587164_39 HAD-hyrolase-like - - - 0.000000001992 60.0
HFD3_k127_4587164_4 PFAM deoxyribose-phosphate aldolase phospho-2- dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 534.0
HFD3_k127_4587164_40 single-stranded DNA binding K03111 - - 0.000000005324 64.0
HFD3_k127_4587164_5 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009239 541.0
HFD3_k127_4587164_6 Glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009645 508.0
HFD3_k127_4587164_7 D-arabinono-1,4-lactone oxidase K16653 - 1.1.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 509.0
HFD3_k127_4587164_8 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 495.0
HFD3_k127_4587164_9 Prephenate dehydrogenase K00210,K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 441.0
HFD3_k127_4620806_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1241.0
HFD3_k127_4620806_1 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 430.0
HFD3_k127_4620806_2 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001245 250.0
HFD3_k127_4620806_3 2Fe-2S -binding K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000007437 239.0
HFD3_k127_4620806_4 PFAM ABC transporter related K09820 - - 0.0000000000000000000000000000000000000000000000000000005119 201.0
HFD3_k127_4620806_5 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000000000000000000000002347 184.0
HFD3_k127_4620806_6 Iron permease FTR1 K07243 - - 0.0000000000000000000000000000000000000000003009 169.0
HFD3_k127_4620806_7 COG1108 ABC-type Mn2 Zn2 transport systems, permease components K19976 - - 0.0000000000000000000000000000000002319 149.0
HFD3_k127_4620806_8 Ferric uptake regulator family K03711 - - 0.0000000000000000003565 94.0
HFD3_k127_4636877_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 3.43e-277 869.0
HFD3_k127_4636877_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 2.381e-242 758.0
HFD3_k127_4636877_2 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 346.0
HFD3_k127_4636877_3 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000543 285.0
HFD3_k127_4636877_4 Saccharopine dehydrogenase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000001522 203.0
HFD3_k127_4636877_5 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000006775 186.0
HFD3_k127_4636877_6 Sterol carrier protein - - - 0.0000000000000000000000000000000000000000000006685 182.0
HFD3_k127_4636877_7 Flavodoxin reductases ferredoxin-NADPH reductases family 1 - - - 0.000000000000000000000000000000002463 137.0
HFD3_k127_4636877_8 Divergent 4Fe-4S mono-cluster K05337 - - 0.0000000000000000000005473 96.0
HFD3_k127_4636877_9 nuclease K01174 - 3.1.31.1 0.000000000000000005285 92.0
HFD3_k127_4723253_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 499.0
HFD3_k127_4723253_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 396.0
HFD3_k127_4723253_10 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000006402 217.0
HFD3_k127_4723253_11 Belongs to the low molecular weight phosphotyrosine protein phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000901 208.0
HFD3_k127_4723253_12 Ribosomal protein L17 K02879 - - 0.000000000000000000000000000000000000000000000000009246 185.0
HFD3_k127_4723253_13 Glyoxalase bleomycin resistance protein dioxygenase - GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0050896 - 0.000000000000000000000000000000000000000000001527 168.0
HFD3_k127_4723253_14 Ribosomal protein S9/S16 K02996 - - 0.000000000000000000000000000000000000000000001555 175.0
HFD3_k127_4723253_15 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000006495 149.0
HFD3_k127_4723253_16 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.000000000000000000000000000000001069 130.0
HFD3_k127_4723253_17 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000000000000001797 132.0
HFD3_k127_4723253_19 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000004675 75.0
HFD3_k127_4723253_2 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 376.0
HFD3_k127_4723253_3 PFAM Glycosyl transferases group 1 K03867 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009317 368.0
HFD3_k127_4723253_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000519 356.0
HFD3_k127_4723253_5 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004781 286.0
HFD3_k127_4723253_6 Glutamine amidotransferase domain K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006733 275.0
HFD3_k127_4723253_7 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000000001956 222.0
HFD3_k127_4723253_8 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000000001335 214.0
HFD3_k127_4723253_9 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000000000000003791 211.0
HFD3_k127_4738192_0 ABC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000592 606.0
HFD3_k127_4738192_1 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006463 526.0
HFD3_k127_4738192_2 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003279 354.0
HFD3_k127_4738192_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000005535 190.0
HFD3_k127_4738192_4 Proline dehydrogenase K13821 - 1.2.1.88,1.5.5.2 0.0000000000000000000000000000000000000001209 158.0
HFD3_k127_4738192_5 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000001504 138.0
HFD3_k127_4789095_0 PFAM 5'-nucleotidase, C-terminal domain K07004 - - 4.23e-247 810.0
HFD3_k127_4789095_1 AMP-forming long-chain acyl-CoA synthetase K01897 - 6.2.1.3 3.983e-246 777.0
HFD3_k127_4789095_10 Bacterial regulatory proteins, luxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005082 399.0
HFD3_k127_4789095_11 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 362.0
HFD3_k127_4789095_12 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 363.0
HFD3_k127_4789095_13 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008394 379.0
HFD3_k127_4789095_14 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000083 349.0
HFD3_k127_4789095_15 pfam abc K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007974 332.0
HFD3_k127_4789095_16 Fatty acid desaturase K00508 - 1.14.19.3 0.0000000000000000000000000000000000000000000000000000000000000000000000002457 263.0
HFD3_k127_4789095_17 COG3209 Rhs family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000947 238.0
HFD3_k127_4789095_18 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000001356 224.0
HFD3_k127_4789095_19 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000005324 157.0
HFD3_k127_4789095_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 4.498e-201 643.0
HFD3_k127_4789095_20 ATP-grasp domain - - - 0.00000000000000000000000000000000269 145.0
HFD3_k127_4789095_21 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000009988 124.0
HFD3_k127_4789095_22 lysyltransferase activity K07027,K20468 - - 0.0000000000000000000002714 110.0
HFD3_k127_4789095_23 Histidine kinase-like ATPases - - - 0.0000000000000000000004102 105.0
HFD3_k127_4789095_24 ATP-grasp domain - - - 0.000000000000001192 84.0
HFD3_k127_4789095_25 response regulator K07684 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0090352,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903314,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000007779 86.0
HFD3_k127_4789095_26 peptidase A24A prepilin type IV K02654 - 3.4.23.43 0.00000000001579 68.0
HFD3_k127_4789095_27 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00000284 54.0
HFD3_k127_4789095_3 Hydroxymethylglutaryl-coenzyme A reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 579.0
HFD3_k127_4789095_4 Putative zinc binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 565.0
HFD3_k127_4789095_5 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004088 547.0
HFD3_k127_4789095_6 winged helix-turn-helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 518.0
HFD3_k127_4789095_7 cyclic nucleotide binding K15762 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004251 491.0
HFD3_k127_4789095_8 Periplasmic binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 417.0
HFD3_k127_4789095_9 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 409.0
HFD3_k127_4797751_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 1.108e-231 725.0
HFD3_k127_4797751_1 Aminotransferase class I and II K14261 - - 7.311e-221 689.0
HFD3_k127_4797751_10 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 409.0
HFD3_k127_4797751_11 transport, permease protein K09694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009568 338.0
HFD3_k127_4797751_12 Glycosyl transferases group 1 K08256 - 2.4.1.345 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 343.0
HFD3_k127_4797751_13 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004296 299.0
HFD3_k127_4797751_14 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000162 246.0
HFD3_k127_4797751_15 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000007369 266.0
HFD3_k127_4797751_16 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000001119 257.0
HFD3_k127_4797751_17 Inositol monophosphatase family K01092 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043167,GO:0043169,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000001009 241.0
HFD3_k127_4797751_18 transport, permease protein K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000002098 236.0
HFD3_k127_4797751_19 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000001128 234.0
HFD3_k127_4797751_2 Acyl-CoA dehydrogenase, N-terminal domain - - - 8.333e-215 671.0
HFD3_k127_4797751_20 Belongs to the TPP enzyme family K03336 - 3.7.1.22 0.0000000000000000000000000000000000000000000000000000000000000004809 224.0
HFD3_k127_4797751_21 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000008787 215.0
HFD3_k127_4797751_22 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000163 170.0
HFD3_k127_4797751_23 Lipoate-protein ligase - - - 0.000000000000000000000000000000000000006142 156.0
HFD3_k127_4797751_24 MraZ protein, putative antitoxin-like K03925 - - 0.00000000000000000000000000000000006221 139.0
HFD3_k127_4797751_25 GDP-mannose mannosyl hydrolase activity K08310 - 3.6.1.67 0.0000000000000000000000000000007475 127.0
HFD3_k127_4797751_28 PFAM Sporulation and spore germination - - - 0.00000001146 65.0
HFD3_k127_4797751_3 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 539.0
HFD3_k127_4797751_31 iron ion binding - - - 0.0003792 52.0
HFD3_k127_4797751_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 494.0
HFD3_k127_4797751_5 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008826 473.0
HFD3_k127_4797751_6 ABC transporter K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003994 446.0
HFD3_k127_4797751_7 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 440.0
HFD3_k127_4797751_8 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 424.0
HFD3_k127_4797751_9 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 442.0
HFD3_k127_4858742_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1451.0
HFD3_k127_4858742_1 Thiamine pyrophosphate enzyme, central domain K03336 - 3.7.1.22 2.009e-213 682.0
HFD3_k127_4858742_10 Myo-inositol 2-dehydrogenase K18652 - 1.1.1.361 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004709 338.0
HFD3_k127_4858742_11 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 326.0
HFD3_k127_4858742_12 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 316.0
HFD3_k127_4858742_13 HhH-GPD superfamily base excision DNA repair protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005222 280.0
HFD3_k127_4858742_14 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K03335 - 4.2.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000002638 261.0
HFD3_k127_4858742_15 Glycosyltransferase like family 2 K20444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000145 263.0
HFD3_k127_4858742_16 Glycosyl transferase, family 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000009028 231.0
HFD3_k127_4858742_17 - - - - 0.00000000000000000000000000000000000000000000000000000000000000248 225.0
HFD3_k127_4858742_18 Protein of unknown function (DUF664) - - - 0.00000000000000000000000000000000000000000000000000000000002088 210.0
HFD3_k127_4858742_19 Fungalysin metallopeptidase (M36) K01417 - - 0.0000000000000000000000000000000000000000000000000000000001069 228.0
HFD3_k127_4858742_2 MMPL family K06994 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008433 553.0
HFD3_k127_4858742_20 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000238 206.0
HFD3_k127_4858742_21 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000011 200.0
HFD3_k127_4858742_22 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000002158 194.0
HFD3_k127_4858742_23 Domain of unknown function (DUF1731) K07071 - - 0.000000000000000000000000000000000000000000000000002234 185.0
HFD3_k127_4858742_24 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000001232 168.0
HFD3_k127_4858742_25 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000005579 156.0
HFD3_k127_4858742_26 - - - - 0.00000000000000000000000000000000000009432 162.0
HFD3_k127_4858742_27 calcium- and calmodulin-responsive adenylate cyclase activity K07260 - 3.4.17.14 0.0000000000000000000000000000000000001155 162.0
HFD3_k127_4858742_28 Predicted membrane protein (DUF2142) - - - 0.000000000000000000000000001753 130.0
HFD3_k127_4858742_29 Glycosyltransferase like family 2 - - - 0.00000000000000000125 101.0
HFD3_k127_4858742_3 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 512.0
HFD3_k127_4858742_4 lipolytic protein G-D-S-L family K01183 - 3.2.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 459.0
HFD3_k127_4858742_5 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 450.0
HFD3_k127_4858742_6 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 429.0
HFD3_k127_4858742_7 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 397.0
HFD3_k127_4858742_8 lipolytic protein G-D-S-L family K01183 - 3.2.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004159 379.0
HFD3_k127_4858742_9 4-hydroxybenzoate 3-monooxygenase K00481 - 1.14.13.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007153 355.0
HFD3_k127_4874199_0 Protein synonym hydantoin utilization protein A K01473 - 3.5.2.14 2.6e-322 1005.0
HFD3_k127_4874199_1 Protein synonym hydantoin utilization protein B K01474 - 3.5.2.14 1.87e-275 854.0
HFD3_k127_4874199_10 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000194 212.0
HFD3_k127_4874199_11 Transcriptional regulator K05799 - - 0.0000000000000000000000000000000000000000000000000000000005803 211.0
HFD3_k127_4874199_12 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000001091 194.0
HFD3_k127_4874199_13 dehydratase - - - 0.000000000000000000000000000000000000000000000000000006457 196.0
HFD3_k127_4874199_14 BetI-type transcriptional repressor, C-terminal - - - 0.00000000000000000000000000000000000000000000000000001598 196.0
HFD3_k127_4874199_15 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000001732 197.0
HFD3_k127_4874199_16 Acetyltransferase (GNAT) domain K03825 - - 0.000000000000000000000000000000000000000000000001732 180.0
HFD3_k127_4874199_17 acyl-L-homoserine-lactone lactonohydrolase activity K13075 - 3.1.1.81 0.00000000000000000000000002779 118.0
HFD3_k127_4874199_2 Zn-dependent metallo-hydrolase RNA specificity domain K12574 - - 5.526e-267 830.0
HFD3_k127_4874199_3 PFAM AMP-dependent synthetase and ligase K02182 - 6.2.1.48 3.017e-208 682.0
HFD3_k127_4874199_4 Ftsk_gamma K03466 - - 1.286e-206 668.0
HFD3_k127_4874199_5 Rieske 2Fe-2S K00479 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 576.0
HFD3_k127_4874199_6 Acyl-CoA dehydrogenase, C-terminal domain K00248,K14448 - 1.3.8.1,1.3.8.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 509.0
HFD3_k127_4874199_7 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 387.0
HFD3_k127_4874199_8 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007903 365.0
HFD3_k127_4874199_9 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.000000000000000000000000000000000000000000000000000000000000000001846 235.0
HFD3_k127_4874326_0 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 4.117e-213 670.0
HFD3_k127_4874326_1 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 1.078e-199 633.0
HFD3_k127_4874326_2 o-methyltransferase K21377 - 2.1.1.302 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 528.0
HFD3_k127_4874326_3 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 524.0
HFD3_k127_4874326_4 Rieske 2Fe-2S - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008603 422.0
HFD3_k127_4874326_5 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009511 410.0
HFD3_k127_4874326_6 P-aminobenzoate N-oxygenase AurF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 403.0
HFD3_k127_4874326_7 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009245 334.0
HFD3_k127_4874326_8 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003002 248.0
HFD3_k127_4902513_0 PFAM tRNA synthetases class I (E and Q), catalytic domain K01886 - 6.1.1.18 2.477e-282 887.0
HFD3_k127_4902513_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676,K01678,K03780 - 4.2.1.2,4.2.1.32 1.984e-281 872.0
HFD3_k127_4902513_10 ABC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 529.0
HFD3_k127_4902513_11 Carbon-nitrogen hydrolase K01431 - 3.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 490.0
HFD3_k127_4902513_12 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 477.0
HFD3_k127_4902513_13 Protein of unknown function (DUF1349) K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009179 454.0
HFD3_k127_4902513_14 F420-dependent oxidoreductase, MSMEG_3544 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 399.0
HFD3_k127_4902513_16 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 351.0
HFD3_k127_4902513_17 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008994 299.0
HFD3_k127_4902513_18 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005906 287.0
HFD3_k127_4902513_19 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006532 246.0
HFD3_k127_4902513_2 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.682e-278 863.0
HFD3_k127_4902513_20 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000007704 242.0
HFD3_k127_4902513_21 DUF218 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000582 248.0
HFD3_k127_4902513_22 PFAM glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001381 253.0
HFD3_k127_4902513_23 Fibronectin type 3 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000005778 253.0
HFD3_k127_4902513_24 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000001313 222.0
HFD3_k127_4902513_25 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000002585 205.0
HFD3_k127_4902513_26 Protein of unknown function (DUF1353) - - - 0.00000000000000000000000000000000000000000000000000000000565 207.0
HFD3_k127_4902513_27 Initiation factor 2 subunit family - - - 0.000000000000000000000000000000000000000000000000000000005839 208.0
HFD3_k127_4902513_28 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000002933 192.0
HFD3_k127_4902513_29 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000006742 201.0
HFD3_k127_4902513_3 ABC transporter - - - 3.754e-240 752.0
HFD3_k127_4902513_30 - - - - 0.000000000000000000000000000000000000000000000000000781 201.0
HFD3_k127_4902513_31 PFAM regulatory protein MarR - - - 0.0000000000000000000000000000000000000000000000002601 181.0
HFD3_k127_4902513_32 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000002358 178.0
HFD3_k127_4902513_33 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000006572 169.0
HFD3_k127_4902513_34 metal cluster binding K06940 - - 0.000000000000000000000000000000000000000005045 166.0
HFD3_k127_4902513_35 lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000822 168.0
HFD3_k127_4902513_36 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000000000000000000006801 160.0
HFD3_k127_4902513_37 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000106 139.0
HFD3_k127_4902513_38 transcriptional regulator - - - 0.0000000000000000000000004063 114.0
HFD3_k127_4902513_39 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000005543 102.0
HFD3_k127_4902513_4 glycine radical enzyme, YjjI family - - - 4.473e-221 696.0
HFD3_k127_4902513_40 Methyltransferase domain - - - 0.0000000000000003195 88.0
HFD3_k127_4902513_41 - - - - 0.000000000000001575 88.0
HFD3_k127_4902513_43 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000008938 64.0
HFD3_k127_4902513_5 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 3.367e-220 697.0
HFD3_k127_4902513_6 Belongs to the amidase family K01426 - 3.5.1.4 1.29e-219 692.0
HFD3_k127_4902513_7 ATP-dependent helicase K03579 - 3.6.4.13 2.726e-209 677.0
HFD3_k127_4902513_8 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 2.033e-194 616.0
HFD3_k127_4902513_9 DNA ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 527.0
HFD3_k127_4902903_0 Salmonella virulence plasmid 65kDa B protein - - - 0.0 1504.0
HFD3_k127_4902903_1 ATPase, P-type K12952 - - 1.942e-225 724.0
HFD3_k127_4902903_10 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000971 312.0
HFD3_k127_4902903_11 C-terminal domain of 1-Cys peroxiredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004976 287.0
HFD3_k127_4902903_12 a CheY-like receiver domain and - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002079 282.0
HFD3_k127_4902903_13 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008051 279.0
HFD3_k127_4902903_14 ABC-type Na efflux pump, permease K01992 - - 0.00000000000000000000000000000000000000000000000000000000000007338 233.0
HFD3_k127_4902903_15 - - - - 0.0000000000000000000000000000000000000000000000000000000002178 211.0
HFD3_k127_4902903_16 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000001081 219.0
HFD3_k127_4902903_17 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000006631 195.0
HFD3_k127_4902903_18 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000001365 179.0
HFD3_k127_4902903_19 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000008982 164.0
HFD3_k127_4902903_2 Protein involved in amylo-alpha-1,6-glucosidase activity and glycogen biosynthetic process - - - 9.277e-197 636.0
HFD3_k127_4902903_20 Histidine kinase - - - 0.00000000000000000000000000000000000000002989 167.0
HFD3_k127_4902903_21 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000001785 152.0
HFD3_k127_4902903_22 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000001414 107.0
HFD3_k127_4902903_23 Clp amino terminal domain, pathogenicity island component K03696 - - 0.0000000000000007474 89.0
HFD3_k127_4902903_24 Histidine kinase - - - 0.000000000000001183 89.0
HFD3_k127_4902903_25 PFAM peptidase M14, carboxypeptidase A - - - 0.0000000000001298 83.0
HFD3_k127_4902903_26 - - - - 0.00000000003851 73.0
HFD3_k127_4902903_27 - - - - 0.00006319 49.0
HFD3_k127_4902903_28 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000663 50.0
HFD3_k127_4902903_3 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 582.0
HFD3_k127_4902903_4 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 434.0
HFD3_k127_4902903_5 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 396.0
HFD3_k127_4902903_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004502 386.0
HFD3_k127_4902903_7 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 348.0
HFD3_k127_4902903_8 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 361.0
HFD3_k127_4902903_9 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 331.0
HFD3_k127_4903037_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.133e-239 754.0
HFD3_k127_4903037_1 P-aminobenzoate N-oxygenase AurF - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009709 505.0
HFD3_k127_4903037_10 Rieske 2Fe-2S - - - 0.00002856 46.0
HFD3_k127_4903037_2 ABC-type polar amino acid transport system ATPase component K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 379.0
HFD3_k127_4903037_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 347.0
HFD3_k127_4903037_4 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006791 342.0
HFD3_k127_4903037_5 Polar amino acid ABC transporter K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001425 289.0
HFD3_k127_4903037_6 Bacterial periplasmic substrate-binding proteins K02030 - - 0.000000000000000000000000000000000000000000000000000000008767 212.0
HFD3_k127_4903037_8 Domain of unknown function (DUF4440) - - - 0.00000000000000000000000000000001408 133.0
HFD3_k127_4903037_9 Bacterial regulatory proteins, tetR family - - - 0.0000000000000001021 87.0
HFD3_k127_4926377_0 hydrolase, family 65, central catalytic K05342 - 2.4.1.64 9.057e-249 803.0
HFD3_k127_4926377_1 Pyruvate:ferredoxin oxidoreductase core domain II K00186 - 1.2.7.7 5.609e-206 650.0
HFD3_k127_4926377_10 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 348.0
HFD3_k127_4926377_11 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 348.0
HFD3_k127_4926377_12 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 291.0
HFD3_k127_4926377_13 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 289.0
HFD3_k127_4926377_14 Beta-phosphoglucomutase family hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000276 272.0
HFD3_k127_4926377_15 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001708 247.0
HFD3_k127_4926377_16 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000006038 222.0
HFD3_k127_4926377_17 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.00000000000000000000000000000000000000000000000000000000000009475 224.0
HFD3_k127_4926377_18 MMPL family K06994,K20470 - - 0.00000000000000000000000000000000000000000000000000000000214 215.0
HFD3_k127_4926377_19 dehydratase - - - 0.0000000000000000000000000000000000000000000000000009633 188.0
HFD3_k127_4926377_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00187 - 1.2.7.7 2.438e-196 640.0
HFD3_k127_4926377_20 Golgi phosphoprotein 3 (GPP34) - - - 0.000000000000000000000000000000000000000000000000004188 197.0
HFD3_k127_4926377_21 PFAM MarR family - - - 0.000000000000000000000000000000000000000000000001328 178.0
HFD3_k127_4926377_22 metal-dependent enzyme of the double-stranded beta helix superfamily - - - 0.00000000000000000000000000000000000000000001516 168.0
HFD3_k127_4926377_23 lactoylglutathione lyase activity K01759 GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0050896 4.4.1.5 0.000000000000000000000000000000000000000003153 163.0
HFD3_k127_4926377_24 peroxiredoxin activity - - - 0.000000000000000000000000000000000001045 149.0
HFD3_k127_4926377_25 SnoaL-like domain - - - 0.0000000000000000000000000000000001735 147.0
HFD3_k127_4926377_26 Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding - - - 0.0000000000000000001248 96.0
HFD3_k127_4926377_27 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000004999 92.0
HFD3_k127_4926377_28 activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation - - - 0.00007463 45.0
HFD3_k127_4926377_29 KR domain K00046 - 1.1.1.69 0.0001146 49.0
HFD3_k127_4926377_3 Domain of unknown function (DUF4162) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 525.0
HFD3_k127_4926377_4 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 546.0
HFD3_k127_4926377_5 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 521.0
HFD3_k127_4926377_6 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 468.0
HFD3_k127_4926377_7 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003753 444.0
HFD3_k127_4926377_8 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005258 409.0
HFD3_k127_4926377_9 Protein involved in transcription factor activity, ATP binding, drug transporter activity, ATPase activity, metal ion binding, regulation of transcription, DNA-dependent, drug transport, metal ion transport, defense response to pathogen and response to antibiotic K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 384.0
HFD3_k127_4927445_0 Phage integrase, N-terminal SAM-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 439.0
HFD3_k127_4927445_1 Transposase IS116 IS110 IS902 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002555 255.0
HFD3_k127_4927445_3 flavoprotein involved in K transport - - - 0.00001471 57.0
HFD3_k127_4984495_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K03520 - 1.2.5.3 2.644e-261 826.0
HFD3_k127_4984495_1 FAD dependent oxidoreductase K19191 - 1.5.3.19 1.463e-221 694.0
HFD3_k127_4984495_10 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 477.0
HFD3_k127_4984495_11 DNA photolyase K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004945 446.0
HFD3_k127_4984495_12 Voltage gated chloride channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 437.0
HFD3_k127_4984495_13 TIGRFAM NRAMP (natural resistance-associated macrophage protein) metal ion transporters - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007864 420.0
HFD3_k127_4984495_14 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 439.0
HFD3_k127_4984495_15 ABC transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009999 397.0
HFD3_k127_4984495_16 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 376.0
HFD3_k127_4984495_17 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003904 342.0
HFD3_k127_4984495_18 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007 340.0
HFD3_k127_4984495_19 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009088 332.0
HFD3_k127_4984495_2 HD domain - - - 1.103e-207 657.0
HFD3_k127_4984495_20 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000136 299.0
HFD3_k127_4984495_21 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003121 271.0
HFD3_k127_4984495_22 PFAM cyclase family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000122 277.0
HFD3_k127_4984495_23 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001284 263.0
HFD3_k127_4984495_24 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002353 268.0
HFD3_k127_4984495_25 TIGRFAM cation diffusion facilitator family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004941 263.0
HFD3_k127_4984495_26 Phosphoesterase family K21302 - 3.1.3.64 0.000000000000000000000000000000000000000000000000000000000000000000000005062 255.0
HFD3_k127_4984495_27 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000379 240.0
HFD3_k127_4984495_28 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000000000000000000004032 228.0
HFD3_k127_4984495_29 Bacterial extracellular solute-binding protein K02020 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0040007,GO:0042597,GO:0043167,GO:0043168,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704 - 0.0000000000000000000000000000000000000000000000000000000000002196 220.0
HFD3_k127_4984495_3 acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 611.0
HFD3_k127_4984495_30 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000371 218.0
HFD3_k127_4984495_31 GyrI-like small molecule binding domain - - - 0.0000000000000000000000000000000000000000000000000002593 192.0
HFD3_k127_4984495_32 hydrolases or acyltransferases alpha beta hydrolase superfamily - - - 0.00000000000000000000000000000000000000000000000205 183.0
HFD3_k127_4984495_33 SMART Rhodanese domain protein - - - 0.00000000000000000000000000000000000000000000002524 173.0
HFD3_k127_4984495_34 - - - - 0.0000000000000000000000000000000000000000000004596 171.0
HFD3_k127_4984495_35 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000001021 173.0
HFD3_k127_4984495_36 N-acetylglucosaminylinositol deacetylase activity - - - 0.0000000000000000000000000000000000000000003349 176.0
HFD3_k127_4984495_37 PFAM DsrC family protein K11179 - - 0.000000000000000000000000000000000000000001463 157.0
HFD3_k127_4984495_38 transcriptional regulator (MarR - - - 0.0000000000000000000000000000000001396 138.0
HFD3_k127_4984495_39 Stage II sporulation protein E (SpoIIE) K07315 - 3.1.3.3 0.0000000000000000000000000000001845 143.0
HFD3_k127_4984495_4 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 607.0
HFD3_k127_4984495_40 Transcriptional regulator PadR-like family K10917 - - 0.00000000000000000000000000000238 127.0
HFD3_k127_4984495_41 hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000003604 128.0
HFD3_k127_4984495_42 involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein - - - 0.0000000000000000000000006145 118.0
HFD3_k127_4984495_43 - - - - 0.000000000000000000000001509 107.0
HFD3_k127_4984495_44 Protein of unknown function (DUF4242) - - - 0.000000000000000000000004324 106.0
HFD3_k127_4984495_45 Domain of unknown function (DU1801) - - - 0.00000000000000000000001185 104.0
HFD3_k127_4984495_47 PFAM regulatory protein, ArsR K03892 - - 0.0000000000000003878 81.0
HFD3_k127_4984495_48 PFAM Hemerythrin HHE cation binding domain protein - - - 0.0000000001955 71.0
HFD3_k127_4984495_49 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000101 61.0
HFD3_k127_4984495_5 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 577.0
HFD3_k127_4984495_6 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008196 582.0
HFD3_k127_4984495_7 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008509 510.0
HFD3_k127_4984495_8 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005641 487.0
HFD3_k127_4984495_9 Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006495 475.0
HFD3_k127_499049_0 metal-dependent phosphohydrolase, HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009799 361.0
HFD3_k127_499049_1 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008359 290.0
HFD3_k127_499049_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000004919 226.0
HFD3_k127_499049_3 Glucose inhibited division protein A - - - 0.000000000002031 69.0
HFD3_k127_499049_4 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0002994 52.0
HFD3_k127_5053092_0 homoserine dehydrogenase - - - 7.939e-208 658.0
HFD3_k127_5053092_1 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 426.0
HFD3_k127_5053092_10 Putative collagen-binding domain of a collagenase - - - 0.00000000000000000000000000000000000000000003024 183.0
HFD3_k127_5053092_11 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000005317 135.0
HFD3_k127_5053092_12 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000003548 120.0
HFD3_k127_5053092_13 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000004696 115.0
HFD3_k127_5053092_2 Nucleotidyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 367.0
HFD3_k127_5053092_3 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 312.0
HFD3_k127_5053092_4 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 301.0
HFD3_k127_5053092_5 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002182 249.0
HFD3_k127_5053092_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000006576 235.0
HFD3_k127_5053092_7 O-acyltransferase activity K00661 - 2.3.1.79 0.000000000000000000000000000000000000000000000000000000002928 205.0
HFD3_k127_5053092_8 PFAM glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000002705 207.0
HFD3_k127_5053092_9 PFAM FecR protein K07279 - - 0.0000000000000000000000000000000000000000000007088 184.0
HFD3_k127_5070129_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 5.084e-233 748.0
HFD3_k127_5070129_1 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 3.047e-224 703.0
HFD3_k127_5070129_10 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 468.0
HFD3_k127_5070129_11 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 451.0
HFD3_k127_5070129_12 3-dehydroquinate synthase K16020 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 443.0
HFD3_k127_5070129_13 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K02549,K19802,K21624 - 4.2.1.113,4.2.1.171,5.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009771 432.0
HFD3_k127_5070129_14 Arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 412.0
HFD3_k127_5070129_15 Domain of unknown function (DUF1989) K09967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006282 412.0
HFD3_k127_5070129_16 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009139 406.0
HFD3_k127_5070129_17 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005446 387.0
HFD3_k127_5070129_18 Proline racemase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 365.0
HFD3_k127_5070129_19 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008317 357.0
HFD3_k127_5070129_2 Aconitase family (aconitate hydratase) K01681 - 4.2.1.3 1.531e-210 663.0
HFD3_k127_5070129_20 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 365.0
HFD3_k127_5070129_21 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 334.0
HFD3_k127_5070129_22 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009073 336.0
HFD3_k127_5070129_23 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 327.0
HFD3_k127_5070129_24 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000067 324.0
HFD3_k127_5070129_25 UTRA K03710 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000686 303.0
HFD3_k127_5070129_27 chromosome partitioning K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009008 293.0
HFD3_k127_5070129_28 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 304.0
HFD3_k127_5070129_29 ABC transporter, ATP-binding protein K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 312.0
HFD3_k127_5070129_3 GTP-binding protein TypA K06207 - - 5.576e-210 673.0
HFD3_k127_5070129_30 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003399 285.0
HFD3_k127_5070129_31 Phosphoglycerate mutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002278 254.0
HFD3_k127_5070129_32 Cytidylate kinase K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000004192 251.0
HFD3_k127_5070129_33 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000007897 253.0
HFD3_k127_5070129_34 D-amino acid K00285 - 1.4.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000009097 257.0
HFD3_k127_5070129_35 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000817 255.0
HFD3_k127_5070129_36 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000001399 210.0
HFD3_k127_5070129_37 Cytochrome oxidase assembly protein K02259 - - 0.0000000000000000000000000000000000000000000000000000001282 207.0
HFD3_k127_5070129_38 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000001737 187.0
HFD3_k127_5070129_39 ornithine cyclodeaminase K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000008114 189.0
HFD3_k127_5070129_4 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006502 611.0
HFD3_k127_5070129_40 Protein of unknown function (DUF3151) - - - 0.00000000000000000000000000000000000000000000000521 175.0
HFD3_k127_5070129_41 BetI-type transcriptional repressor, C-terminal - - - 0.000000000000000000000000000000000000000005595 169.0
HFD3_k127_5070129_42 - - - - 0.000000000000000000000000000000000000001238 153.0
HFD3_k127_5070129_43 Heat shock protein DnaJ domain protein K05516 - - 0.000000000000000000000000000000000000005946 152.0
HFD3_k127_5070129_44 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000000000000768 145.0
HFD3_k127_5070129_45 Catalyzes a trans-dehydration via an enolate intermediate K03786,K16021 - 4.2.1.10 0.00000000000000000000000000000003901 130.0
HFD3_k127_5070129_46 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000003728 130.0
HFD3_k127_5070129_47 EamA-like transporter family - - - 0.0000000000000000000000007288 114.0
HFD3_k127_5070129_48 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.7.77 0.00000000000000000000003043 106.0
HFD3_k127_5070129_49 Rhodanese Homology Domain - - - 0.000000000000000000001424 102.0
HFD3_k127_5070129_5 xylulose kinase K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 556.0
HFD3_k127_5070129_52 Putative stress-induced transcription regulator - - - 0.000001027 55.0
HFD3_k127_5070129_6 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006261 531.0
HFD3_k127_5070129_7 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 513.0
HFD3_k127_5070129_8 3'-5' exonuclease K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 479.0
HFD3_k127_5070129_9 M18 family aminopeptidase K01267 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.11.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007504 482.0
HFD3_k127_50800_0 ATPase P-type (Transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 5e-324 1014.0
HFD3_k127_50800_1 heavy metal translocating P-type ATPase K01533 - 3.6.3.4 8.166e-274 856.0
HFD3_k127_50800_10 Belongs to the thiolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006669 475.0
HFD3_k127_50800_11 PFAM AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 471.0
HFD3_k127_50800_12 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009419 442.0
HFD3_k127_50800_13 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009879 430.0
HFD3_k127_50800_14 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 415.0
HFD3_k127_50800_15 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 401.0
HFD3_k127_50800_16 ABC1 family K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 402.0
HFD3_k127_50800_17 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 378.0
HFD3_k127_50800_18 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008698 370.0
HFD3_k127_50800_19 Multicopper K06324 - 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004838 370.0
HFD3_k127_50800_2 penicillin-binding protein - - - 2.47e-250 793.0
HFD3_k127_50800_20 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 359.0
HFD3_k127_50800_21 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 357.0
HFD3_k127_50800_22 F420-dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 355.0
HFD3_k127_50800_23 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 343.0
HFD3_k127_50800_24 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007988 334.0
HFD3_k127_50800_25 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 340.0
HFD3_k127_50800_26 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 335.0
HFD3_k127_50800_27 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000529 316.0
HFD3_k127_50800_28 Enoyl-(Acyl carrier protein) reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 311.0
HFD3_k127_50800_29 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 301.0
HFD3_k127_50800_3 ABC transporter transmembrane region K06147 - - 4.948e-240 764.0
HFD3_k127_50800_30 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 295.0
HFD3_k127_50800_31 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000483 289.0
HFD3_k127_50800_32 dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003432 279.0
HFD3_k127_50800_33 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005816 273.0
HFD3_k127_50800_34 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004535 271.0
HFD3_k127_50800_35 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003361 271.0
HFD3_k127_50800_36 Enoyl-CoA hydratase/isomerase K01692,K07546 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000001504 259.0
HFD3_k127_50800_37 ABC-type branched-chain amino acid transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009063 277.0
HFD3_k127_50800_38 Exporter of polyketide K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001453 270.0
HFD3_k127_50800_39 Ankyrin repeats (3 copies) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002616 259.0
HFD3_k127_50800_4 ABC transporter transmembrane region K06147 - - 5.02e-235 760.0
HFD3_k127_50800_40 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001514 260.0
HFD3_k127_50800_41 Pfam Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001049 253.0
HFD3_k127_50800_42 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001123 247.0
HFD3_k127_50800_43 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000009902 239.0
HFD3_k127_50800_44 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000000001755 226.0
HFD3_k127_50800_45 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000001534 212.0
HFD3_k127_50800_46 Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000001709 216.0
HFD3_k127_50800_47 - - - - 0.0000000000000000000000000000000000000000000000001545 180.0
HFD3_k127_50800_48 Protein of unknown function (DUF1003) - - - 0.000000000000000000000000000000000000000000000008179 175.0
HFD3_k127_50800_49 Protein of unknown function (DUF1232) - - - 0.00000000000000000000000000000000000000000000001466 173.0
HFD3_k127_50800_5 Phosphoesterase family - - - 7.227e-233 736.0
HFD3_k127_50800_50 alpha-ribazole phosphatase activity K02226,K15634,K22305,K22306,K22316 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.3,3.1.3.73,3.1.3.85,5.4.2.12 0.0000000000000000000000000000000000000000000002126 173.0
HFD3_k127_50800_51 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000008148 161.0
HFD3_k127_50800_52 - - - - 0.0000000000000000000000000000000000001411 147.0
HFD3_k127_50800_53 COGs COG0300 Short-chain dehydrogenase of various substrate specificities - - - 0.0000000000000000000000000000000000004785 150.0
HFD3_k127_50800_54 - - - - 0.000000000000000000000000000000003941 132.0
HFD3_k127_50800_55 - K07164,K22391 - 3.5.4.16 0.00000000000000000000000003261 117.0
HFD3_k127_50800_56 - - - - 0.0000000000000000000000009633 104.0
HFD3_k127_50800_57 Cold shock protein K03704 - - 0.0000000000000000000003101 98.0
HFD3_k127_50800_58 lactoylglutathione lyase activity - - - 0.000000000000000000004698 97.0
HFD3_k127_50800_59 sigma-70 region 2 K03088 - - 0.0000000000000000004658 97.0
HFD3_k127_50800_6 Aldehyde dehydrogenase K00128,K22187 - 1.2.1.3 7.683e-195 630.0
HFD3_k127_50800_60 helix_turn_helix, cAMP Regulatory protein K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.000000000000000001796 95.0
HFD3_k127_50800_61 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.00000000000000003462 93.0
HFD3_k127_50800_63 COG2309 Leucyl aminopeptidase (aminopeptidase T) K18028 - 1.13.11.9 0.000000000000005657 81.0
HFD3_k127_50800_64 STAS domain K04749 - - 0.00000000000005213 76.0
HFD3_k127_50800_65 Belongs to the 'phage' integrase family - - - 0.0000000000001982 75.0
HFD3_k127_50800_66 - K01992 - - 0.0000000000003345 79.0
HFD3_k127_50800_67 - - - - 0.000000000001193 73.0
HFD3_k127_50800_68 CsbD-like - - - 0.000000000002524 70.0
HFD3_k127_50800_69 Cytochrome b K03887 - - 0.000000000009574 77.0
HFD3_k127_50800_7 Flavin containing amine oxidoreductase - - - 4.487e-194 619.0
HFD3_k127_50800_70 Copper binding proteins, plastocyanin/azurin family - - - 0.0000682 52.0
HFD3_k127_50800_71 STAS domain K04749 - - 0.0002934 48.0
HFD3_k127_50800_72 antisigma factor binding - - - 0.0009318 47.0
HFD3_k127_50800_8 The glycine cleavage system catalyzes the degradation of glycine K00605,K15066 - 2.1.1.341,2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 522.0
HFD3_k127_50800_9 Belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006346 485.0
HFD3_k127_5087365_0 PFAM glycoside hydrolase family 77 K00705 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.4.1.25 2.225e-253 796.0
HFD3_k127_5087365_1 Putative serine esterase (DUF676) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 373.0
HFD3_k127_5087365_2 Domain of unknown function (DUF333) K09712 - - 0.0000000000000003898 82.0
HFD3_k127_5087365_3 Bacterial regulatory proteins, tetR family - - - 0.00000000567 62.0
HFD3_k127_5087365_4 Transposase - - - 0.00000001551 63.0
HFD3_k127_5087365_5 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids - - - 0.0000000806 60.0
HFD3_k127_5149809_0 Non-essential cell division protein that could be required for efficient cell constriction - - - 3.655e-268 868.0
HFD3_k127_5149809_1 AAA domain (dynein-related subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007567 559.0
HFD3_k127_5149809_2 PFAM zinc finger SWIM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749 542.0
HFD3_k127_5149809_3 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K04127,K11325,K21174 - 5.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003968 421.0
HFD3_k127_5149809_4 Nuclease-related domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001217 245.0
HFD3_k127_5149809_5 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000004664 248.0
HFD3_k127_5149809_6 VWA containing CoxE family protein - - - 0.000000000000000000000000183 110.0
HFD3_k127_5149809_7 RNA polymerase II transcriptional preinitiation complex assembly - - - 0.000000002463 69.0
HFD3_k127_5217851_0 Protein kinase G rubredoxin domain K14949 GO:0001898,GO:0001899,GO:0002682,GO:0002684,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006464,GO:0006468,GO:0006520,GO:0006536,GO:0006538,GO:0006541,GO:0006543,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009405,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0019752,GO:0030100,GO:0031341,GO:0031342,GO:0031347,GO:0031349,GO:0032879,GO:0035821,GO:0036211,GO:0040007,GO:0042268,GO:0042802,GO:0043170,GO:0043207,GO:0043412,GO:0043436,GO:0043648,GO:0043649,GO:0043900,GO:0043901,GO:0043903,GO:0044003,GO:0044068,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044267,GO:0044281,GO:0044282,GO:0044403,GO:0044413,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044501,GO:0045918,GO:0046395,GO:0046777,GO:0048518,GO:0048519,GO:0048523,GO:0048583,GO:0048584,GO:0050764,GO:0050776,GO:0050778,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0051709,GO:0051710,GO:0051711,GO:0051713,GO:0051802,GO:0051803,GO:0051817,GO:0051832,GO:0052027,GO:0052031,GO:0052164,GO:0052173,GO:0052190,GO:0052200,GO:0052231,GO:0052250,GO:0052255,GO:0052303,GO:0052348,GO:0052369,GO:0052509,GO:0052510,GO:0052550,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052567,GO:0052572,GO:0060627,GO:0065007,GO:0071704,GO:0071944,GO:0075136,GO:0080134,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.11.1 1.295e-198 642.0
HFD3_k127_5217851_1 von Willebrand factor type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 430.0
HFD3_k127_5217851_2 Serine/threonine phosphatases, family 2C, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000006808 223.0
HFD3_k127_5217851_3 Trypsin-like serine protease - - - 0.000000000000000000000000000000000000000000000000000008605 200.0
HFD3_k127_5217851_4 metalloendopeptidase activity K03799 - - 0.0000000000000000000000000000000000000000000004444 180.0
HFD3_k127_5217851_5 Domain of unknown function (DUF4328) - - - 0.00000000000000008281 93.0
HFD3_k127_5217851_6 - - - - 0.0000000000005985 74.0
HFD3_k127_5218354_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 5.176e-196 624.0
HFD3_k127_5218354_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 597.0
HFD3_k127_5218354_10 binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000000000000005517 197.0
HFD3_k127_5218354_11 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000000003658 161.0
HFD3_k127_5218354_12 Ribosomal protein L30p/L7e K02907 - - 0.0000000000001689 81.0
HFD3_k127_5218354_13 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000003592 52.0
HFD3_k127_5218354_2 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 411.0
HFD3_k127_5218354_3 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 387.0
HFD3_k127_5218354_4 CYTH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006885 371.0
HFD3_k127_5218354_5 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 311.0
HFD3_k127_5218354_6 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006793 274.0
HFD3_k127_5218354_7 Methionine aminopeptidase K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000354 257.0
HFD3_k127_5218354_8 Phosphoribosyl transferase domain K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000004104 232.0
HFD3_k127_5218354_9 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000002754 214.0
HFD3_k127_53571_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain II K01835,K01840 - 5.4.2.2,5.4.2.8 3.72e-202 648.0
HFD3_k127_53571_1 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 568.0
HFD3_k127_53571_10 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000004821 198.0
HFD3_k127_53571_2 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006471 483.0
HFD3_k127_53571_3 Phytanoyl-CoA dioxygenase (PhyH) K00477,K18565 - 1.14.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 414.0
HFD3_k127_53571_4 Peptidase family M1 domain K08776 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000937 394.0
HFD3_k127_53571_5 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 389.0
HFD3_k127_53571_6 ABC transporter K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 366.0
HFD3_k127_53571_7 histone deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008101 297.0
HFD3_k127_53571_8 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001647 290.0
HFD3_k127_53571_9 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000002676 256.0
HFD3_k127_5408155_0 Histidine kinase - - - 0.0 2067.0
HFD3_k127_5408155_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 588.0
HFD3_k127_5408155_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 324.0
HFD3_k127_5408155_3 Sigma factor PP2C-like phosphatases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004752 324.0
HFD3_k127_5408155_4 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003238 260.0
HFD3_k127_5408155_5 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000002202 87.0
HFD3_k127_5408155_7 Belongs to the anti-sigma-factor antagonist family K06378 - - 0.000000001101 64.0
HFD3_k127_5437466_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1612.0
HFD3_k127_5437466_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1092.0
HFD3_k127_5437466_10 PFAM AMP-dependent synthetase and ligase K00666 - - 1.207e-226 713.0
HFD3_k127_5437466_100 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000003777 118.0
HFD3_k127_5437466_101 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000002171 122.0
HFD3_k127_5437466_102 PFAM regulatory protein, MarR - - - 0.000000000000000000000008988 106.0
HFD3_k127_5437466_103 unsaturated fatty acid biosynthetic process - - - 0.00000000000000000000135 110.0
HFD3_k127_5437466_104 - - - - 0.00000000000000001615 91.0
HFD3_k127_5437466_105 Alpha/beta hydrolase family - - - 0.000000000000004506 84.0
HFD3_k127_5437466_106 phosphatase activity K07025 - - 0.00000002664 65.0
HFD3_k127_5437466_108 Sporulation and spore germination - - - 0.000003165 57.0
HFD3_k127_5437466_11 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K03520 - 1.2.5.3 1.26e-223 721.0
HFD3_k127_5437466_12 Ribosomal protein S1-like RNA-binding domain K02945 - - 1.684e-217 682.0
HFD3_k127_5437466_13 4-hydroxyphenylacetate 3-monooxygenase oxygenase K00483 - 1.14.14.9 2.392e-215 678.0
HFD3_k127_5437466_14 Acyclic terpene utilisation family protein AtuA - - - 1.396e-201 649.0
HFD3_k127_5437466_15 Acyl transferase domain K00645 - 2.3.1.39 9.472e-199 624.0
HFD3_k127_5437466_16 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 4.17e-198 622.0
HFD3_k127_5437466_17 Acetyl propionyl-CoA carboxylase, alpha subunit K01959,K01965,K01968 - 6.4.1.1,6.4.1.3,6.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003432 601.0
HFD3_k127_5437466_18 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483 - 1.14.14.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009508 563.0
HFD3_k127_5437466_19 COGs COG0620 Methionine synthase II (cobalamin-independent) K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 532.0
HFD3_k127_5437466_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 1.14e-313 970.0
HFD3_k127_5437466_20 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 540.0
HFD3_k127_5437466_21 Methionine synthase K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 527.0
HFD3_k127_5437466_22 chorismate binding enzyme K02552 - 5.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 518.0
HFD3_k127_5437466_23 Protein synonym acyl-CoA synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 514.0
HFD3_k127_5437466_24 4-hydroxybenzoate K00481 - 1.14.13.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006125 500.0
HFD3_k127_5437466_25 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 494.0
HFD3_k127_5437466_26 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 - 2.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 488.0
HFD3_k127_5437466_27 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006557 458.0
HFD3_k127_5437466_28 AAA domain K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009199 451.0
HFD3_k127_5437466_29 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 442.0
HFD3_k127_5437466_3 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 7.008e-311 975.0
HFD3_k127_5437466_30 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K00446 - 1.13.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 436.0
HFD3_k127_5437466_31 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007578 430.0
HFD3_k127_5437466_32 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 416.0
HFD3_k127_5437466_33 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000054 408.0
HFD3_k127_5437466_34 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 377.0
HFD3_k127_5437466_35 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 392.0
HFD3_k127_5437466_36 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004575 370.0
HFD3_k127_5437466_37 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 375.0
HFD3_k127_5437466_38 AMP-binding enzyme C-terminal domain K01911 - 6.2.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 374.0
HFD3_k127_5437466_39 Amidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005223 369.0
HFD3_k127_5437466_4 indolepyruvate ferredoxin oxidoreductase K00179,K04090 - 1.2.7.8 3.715e-306 978.0
HFD3_k127_5437466_40 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain K21023 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 379.0
HFD3_k127_5437466_41 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 353.0
HFD3_k127_5437466_42 Carbon-nitrogen hydrolase K01501 - 3.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 362.0
HFD3_k127_5437466_43 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006811 344.0
HFD3_k127_5437466_44 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 353.0
HFD3_k127_5437466_45 Periplasmic binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 349.0
HFD3_k127_5437466_46 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 336.0
HFD3_k127_5437466_47 Zinc-binding dehydrogenase K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007161 325.0
HFD3_k127_5437466_48 Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 340.0
HFD3_k127_5437466_49 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 330.0
HFD3_k127_5437466_5 elongation factor Tu domain 2 protein K02355 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944 - 2.924e-288 902.0
HFD3_k127_5437466_50 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 320.0
HFD3_k127_5437466_51 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 311.0
HFD3_k127_5437466_52 Transporter associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004953 323.0
HFD3_k127_5437466_53 hydratase K01617,K02509 - 4.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 313.0
HFD3_k127_5437466_54 methyltransferase K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 309.0
HFD3_k127_5437466_55 ANTAR K22010 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 301.0
HFD3_k127_5437466_56 Branched-chain amino acid ATP-binding cassette transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007108 315.0
HFD3_k127_5437466_57 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003565 312.0
HFD3_k127_5437466_58 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001735 288.0
HFD3_k127_5437466_59 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001817 287.0
HFD3_k127_5437466_6 AMP-binding enzyme C-terminal domain K00666 - - 5.078e-254 792.0
HFD3_k127_5437466_60 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004174 288.0
HFD3_k127_5437466_61 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002481 289.0
HFD3_k127_5437466_62 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005625 284.0
HFD3_k127_5437466_63 Drug resistance transporter, bcr cfla subfamily K07552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002126 281.0
HFD3_k127_5437466_64 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003144 268.0
HFD3_k127_5437466_65 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000004668 265.0
HFD3_k127_5437466_66 Protocatechuate 3,4-dioxygenase beta subunit N terminal K00449 - 1.13.11.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001392 268.0
HFD3_k127_5437466_67 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004072 259.0
HFD3_k127_5437466_68 protocatechuate 3,4-dioxygenase, beta subunit' K03381 - 1.13.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000766 254.0
HFD3_k127_5437466_69 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008543 253.0
HFD3_k127_5437466_7 Carboxyl transferase domain - - - 8.409e-247 788.0
HFD3_k127_5437466_70 Dithiol-disulfide isomerase involved in polyketide biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002928 244.0
HFD3_k127_5437466_71 Phosphotransferase K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000001037 252.0
HFD3_k127_5437466_72 alpha/beta hydrolase fold K08680 - 4.2.99.20 0.000000000000000000000000000000000000000000000000000000000000000003748 234.0
HFD3_k127_5437466_73 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000004456 237.0
HFD3_k127_5437466_74 - - - - 0.00000000000000000000000000000000000000000000000000000000000000248 225.0
HFD3_k127_5437466_75 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K07684 - - 0.000000000000000000000000000000000000000000000000000000000000002844 224.0
HFD3_k127_5437466_76 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000001118 212.0
HFD3_k127_5437466_77 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000503 210.0
HFD3_k127_5437466_78 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000719 205.0
HFD3_k127_5437466_79 Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant K06720 - 4.2.1.108 0.00000000000000000000000000000000000000000000000000000003094 201.0
HFD3_k127_5437466_8 helicase K03722 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.4.12 4.702e-244 770.0
HFD3_k127_5437466_80 FabA-like domain K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000002739 202.0
HFD3_k127_5437466_81 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000000000000000000001489 204.0
HFD3_k127_5437466_82 Dioxygenase K00448 - 1.13.11.3 0.000000000000000000000000000000000000000000000000006055 194.0
HFD3_k127_5437466_83 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000003136 189.0
HFD3_k127_5437466_84 proteolysis K19225 - 3.4.21.105 0.000000000000000000000000000000000000000000000001487 184.0
HFD3_k127_5437466_85 phosphorelay sensor kinase activity K03406,K07673,K07675 - 2.7.13.3 0.000000000000000000000000000000000000000000000001815 195.0
HFD3_k127_5437466_86 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000000000000000004188 176.0
HFD3_k127_5437466_87 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000002814 179.0
HFD3_k127_5437466_88 TIGRFAM deazaflavin-dependent nitroreductase family protein - - - 0.000000000000000000000000000000000000000000001335 168.0
HFD3_k127_5437466_89 PFAM Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000001287 172.0
HFD3_k127_5437466_9 Catalyzes the attachment of glycine to tRNA(Gly) K01880 - 6.1.1.14 1.4e-236 736.0
HFD3_k127_5437466_90 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000001906 170.0
HFD3_k127_5437466_91 phosphodiesterase - - - 0.00000000000000000000000000000000000000000002413 186.0
HFD3_k127_5437466_92 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756,K01857 - 4.3.2.2,5.5.1.2 0.00000000000000000000000000000000000000000003091 174.0
HFD3_k127_5437466_94 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000007774 169.0
HFD3_k127_5437466_95 Transcriptional regulator - - - 0.00000000000000000000000000000000000005056 154.0
HFD3_k127_5437466_96 transferase activity, transferring alkyl or aryl (other than methyl) groups K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.00000000000000000000000000000000000005792 149.0
HFD3_k127_5437466_97 3-oxoadipate enol-lactonase K01055,K14727 - 3.1.1.24,4.1.1.44 0.0000000000000000000000000000000007473 138.0
HFD3_k127_5437466_98 Protein of unknown function (DUF1810) - - - 0.0000000000000000000000000000001081 133.0
HFD3_k127_5437466_99 succinyl-diaminopimelate desuccinylase activity - - - 0.00000000000000000000000000002798 133.0
HFD3_k127_5450653_0 Protein of unknown function (DUF3494) - - - 0.000000000000000000000000000000000000000001416 165.0
HFD3_k127_5450653_1 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000001761 160.0
HFD3_k127_5450653_2 AAA ATPase domain - - - 0.00000000000000000000000000000000001885 157.0
HFD3_k127_5450653_3 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000005881 137.0
HFD3_k127_5450653_4 PFAM transposase IS116 IS110 IS902 family protein - - - 0.00000000000000000000000000000000781 134.0
HFD3_k127_5450653_5 DDE domain K07497 - - 0.000000000000005295 81.0
HFD3_k127_5450653_6 antisigma factor binding K04749,K17763,K20978 - - 0.00000004911 59.0
HFD3_k127_5450653_9 antisigma factor binding K06378 - - 0.000119 49.0
HFD3_k127_5456606_0 C-terminal, D2-small domain, of ClpB protein K03695 - - 5.733e-194 609.0
HFD3_k127_5456606_1 SNF2 family N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 630.0
HFD3_k127_5456606_2 Two component transcriptional regulator, winged helix family K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002924 284.0
HFD3_k127_5456606_3 Lysine methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009746 261.0
HFD3_k127_5456606_4 - - - - 0.00000000000000000000000000000004848 136.0
HFD3_k127_5456606_5 SWIM zinc finger - - - 0.00000000003119 73.0
HFD3_k127_5481225_0 Rieske 2Fe-2S K14952 - - 9.789e-219 689.0
HFD3_k127_5481225_10 Protein of unknown function (DUF2510) - - - 0.00000000000000003092 89.0
HFD3_k127_5481225_11 Cyclic nucleotide-binding domain - - - 0.00000000000002675 81.0
HFD3_k127_5481225_13 procollagen-lysine 5-dioxygenase activity K00473,K13645,K13646,K13647,K15174 GO:0000003,GO:0000902,GO:0000904,GO:0001666,GO:0001701,GO:0001885,GO:0001886,GO:0002009,GO:0002064,GO:0003006,GO:0003008,GO:0003013,GO:0003018,GO:0003158,GO:0003382,GO:0003674,GO:0003824,GO:0003980,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0005791,GO:0005794,GO:0005802,GO:0006011,GO:0006082,GO:0006139,GO:0006464,GO:0006486,GO:0006493,GO:0006520,GO:0006575,GO:0006725,GO:0006793,GO:0006807,GO:0006950,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007295,GO:0007399,GO:0008015,GO:0008104,GO:0008150,GO:0008152,GO:0008194,GO:0008198,GO:0008378,GO:0008475,GO:0008544,GO:0008652,GO:0009058,GO:0009059,GO:0009066,GO:0009067,GO:0009100,GO:0009101,GO:0009225,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009987,GO:0010033,GO:0012505,GO:0016020,GO:0016043,GO:0016053,GO:0016491,GO:0016705,GO:0016706,GO:0016740,GO:0016757,GO:0016758,GO:0017185,GO:0018126,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0019842,GO:0019953,GO:0021915,GO:0022412,GO:0022414,GO:0022607,GO:0030154,GO:0030198,GO:0030199,GO:0030246,GO:0030323,GO:0030324,GO:0030855,GO:0030867,GO:0031012,GO:0031090,GO:0031406,GO:0031418,GO:0031984,GO:0032501,GO:0032502,GO:0032504,GO:0032870,GO:0032963,GO:0032964,GO:0032989,GO:0032991,GO:0033036,GO:0033218,GO:0033823,GO:0034641,GO:0034645,GO:0035150,GO:0035250,GO:0035251,GO:0035295,GO:0035296,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042175,GO:0042221,GO:0042277,GO:0042311,GO:0042398,GO:0042802,GO:0042803,GO:0043009,GO:0043062,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043413,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045446,GO:0046394,GO:0046483,GO:0046527,GO:0046872,GO:0046914,GO:0046946,GO:0046947,GO:0046983,GO:0048029,GO:0048037,GO:0048468,GO:0048471,GO:0048477,GO:0048513,GO:0048589,GO:0048609,GO:0048729,GO:0048730,GO:0048731,GO:0048856,GO:0048869,GO:0050211,GO:0050662,GO:0050880,GO:0050896,GO:0051179,GO:0051213,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060425,GO:0060429,GO:0060541,GO:0062023,GO:0065007,GO:0065008,GO:0070085,GO:0070482,GO:0070815,GO:0070831,GO:0070887,GO:0071310,GO:0071495,GO:0071704,GO:0071711,GO:0071840,GO:0090066,GO:0097359,GO:0097435,GO:0097746,GO:0097755,GO:0098588,GO:0098791,GO:0098827,GO:0140096,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 1.14.11.4,2.4.1.50,2.4.1.66 0.00000000001978 72.0
HFD3_k127_5481225_14 - - - - 0.0003186 52.0
HFD3_k127_5481225_2 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 331.0
HFD3_k127_5481225_3 ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006543 297.0
HFD3_k127_5481225_4 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003302 296.0
HFD3_k127_5481225_5 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000001355 271.0
HFD3_k127_5481225_6 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002919 276.0
HFD3_k127_5481225_7 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000003047 261.0
HFD3_k127_5481225_8 AIR carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000001803 223.0
HFD3_k127_5481225_9 Thioesterase-like superfamily - - - 0.00000000000000000000000000000000000003713 151.0
HFD3_k127_5487515_0 Protein synonym acyl-CoA synthetase K01897 - 6.2.1.3 9.106e-255 797.0
HFD3_k127_5487515_1 Protein of unknown function (DUF512) - - - 1.21e-212 671.0
HFD3_k127_5487515_10 and related - - - 0.0000000000000000000000000000000000000000000001702 180.0
HFD3_k127_5487515_11 copper resistance K07245,K14166 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000001605 124.0
HFD3_k127_5487515_12 Transglutaminase-like superfamily - - - 0.000000000000000000000000000132 130.0
HFD3_k127_5487515_2 Acyl-CoA dehydrogenase, N-terminal domain - - - 9.917e-204 639.0
HFD3_k127_5487515_3 Aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 541.0
HFD3_k127_5487515_4 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 524.0
HFD3_k127_5487515_5 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005894 495.0
HFD3_k127_5487515_6 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 379.0
HFD3_k127_5487515_7 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004131 286.0
HFD3_k127_5487515_8 FMN binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009796 264.0
HFD3_k127_5487515_9 FAD binding domain - - - 0.0000000000000000000000000000000000000000000001591 182.0
HFD3_k127_5487843_0 AICARFT/IMPCHase bienzyme K00602 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007395 552.0
HFD3_k127_5487843_1 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 511.0
HFD3_k127_5487843_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 489.0
HFD3_k127_5487843_3 - - - - 0.000000000000000000000000001679 128.0
HFD3_k127_5498425_0 Epoxide hydrolase N terminus K21159 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 593.0
HFD3_k127_5498425_1 Transketolase, C-terminal domain K00167 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 590.0
HFD3_k127_5498425_10 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000001824 252.0
HFD3_k127_5498425_11 NAD(P)H dehydrogenase (quinone) activity K00355 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000001594 220.0
HFD3_k127_5498425_12 DoxX K15977 - - 0.000000000000000000000000000000000000000000000000000004068 196.0
HFD3_k127_5498425_13 NAD(P)H dehydrogenase (quinone) activity K00355 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000006415 199.0
HFD3_k127_5498425_14 LysE type translocator - - - 0.00000000000000000000000000000000000000000000000000004911 194.0
HFD3_k127_5498425_15 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000000000000000000000000000000000003213 175.0
HFD3_k127_5498425_16 Protein of unknown function (DUF664) - - - 0.00000000000000000000000000000000000000000001796 166.0
HFD3_k127_5498425_17 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000002722 171.0
HFD3_k127_5498425_18 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000001999 166.0
HFD3_k127_5498425_19 Protein of unknown function (DUF2469) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000009518 129.0
HFD3_k127_5498425_2 Dehydrogenase E1 component K00166 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 558.0
HFD3_k127_5498425_21 nuclease activity K07460 - - 0.0000000000000000000000000002402 119.0
HFD3_k127_5498425_22 Lysylphosphatidylglycerol synthase TM region - - - 0.000000000000000000000000003214 128.0
HFD3_k127_5498425_23 PAP2 superfamily - - - 0.000000000000000000000000005878 123.0
HFD3_k127_5498425_24 - - - - 0.0000000000001413 81.0
HFD3_k127_5498425_25 Lipid A biosynthesis K02517 - 2.3.1.241 0.000000003016 68.0
HFD3_k127_5498425_3 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K09699 - 2.3.1.168 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 444.0
HFD3_k127_5498425_4 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002922 345.0
HFD3_k127_5498425_5 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005128 307.0
HFD3_k127_5498425_6 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000546 291.0
HFD3_k127_5498425_7 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005527 260.0
HFD3_k127_5498425_8 dioxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006051 270.0
HFD3_k127_5498425_9 Short-chain dehydrogenase reductase sdr - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000224 249.0
HFD3_k127_5508832_0 acyl-CoA dehydrogenase activity - - - 9.504e-234 736.0
HFD3_k127_5508832_1 Ketoacyl-synthetase C-terminal extension - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 529.0
HFD3_k127_5508832_2 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001017 282.0
HFD3_k127_5508832_3 Protein of unknown function (DUF3376) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002692 282.0
HFD3_k127_5508832_4 ABC-type Na efflux pump, permease K01992 - - 0.000000000000000000000000000000000000000000000000000000000000001435 233.0
HFD3_k127_5508832_6 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.00000000000000000000000000000005555 136.0
HFD3_k127_5508832_7 - - - - 0.0006407 49.0
HFD3_k127_5534606_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 6.1.1.15 1.553e-274 855.0
HFD3_k127_5534606_1 geranylgeranyl reductase K21401 - 1.3.99.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 514.0
HFD3_k127_5534606_2 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 473.0
HFD3_k127_5534606_3 dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008854 417.0
HFD3_k127_5534606_4 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 404.0
HFD3_k127_5534606_6 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000000000000000000002785 185.0
HFD3_k127_5534606_7 - - - - 0.00001468 55.0
HFD3_k127_5547078_0 HypF finger K04656 - - 3.14e-226 731.0
HFD3_k127_5547078_1 AIR synthase related protein, C-terminal domain K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 511.0
HFD3_k127_5547078_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 455.0
HFD3_k127_5547078_3 HupF/HypC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004674 258.0
HFD3_k127_5547078_4 SIS domain K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000001659 233.0
HFD3_k127_5547078_5 SPFH domain Band 7 family - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000002108 217.0
HFD3_k127_5547078_6 Hydrogenase/urease nickel incorporation, metallochaperone, hypA K04651 - - 0.0000000000000000000001437 105.0
HFD3_k127_5547078_7 Exporter of polyketide K01992 - - 0.000000004634 69.0
HFD3_k127_5547078_8 NfeD-like C-terminal, partner-binding - - - 0.00009202 51.0
HFD3_k127_5551949_0 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001902 277.0
HFD3_k127_5551949_1 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000003943 117.0
HFD3_k127_5551949_2 COG NOG14451 non supervised orthologous group - - - 0.00000000000002518 83.0
HFD3_k127_5560272_0 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007954 459.0
HFD3_k127_5560272_1 ADP-ribosylglycohydrolase K05521 - 3.2.2.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 418.0
HFD3_k127_5560272_10 - - - - 0.0005682 49.0
HFD3_k127_5560272_2 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 349.0
HFD3_k127_5560272_3 Periplasmic binding protein domain K10439 - - 0.000000000000000000000000000000000000000000000000000000001552 214.0
HFD3_k127_5560272_4 MaoC like domain - - - 0.00000000000000000000000000000000000000000001112 165.0
HFD3_k127_5560272_5 Protein of unknown function (DUF1345) - - - 0.00000000000000000000000000000000000000000001248 180.0
HFD3_k127_5560272_6 - - - - 0.0000000000000000000000000000000001355 136.0
HFD3_k127_5560272_7 PDZ DHR GLGF domain protein K07177 - - 0.00000007411 64.0
HFD3_k127_5560272_8 flavin adenine dinucleotide binding - - - 0.000001407 58.0
HFD3_k127_5560272_9 PAS fold - - - 0.00001846 57.0
HFD3_k127_5586140_0 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 602.0
HFD3_k127_5586140_1 Phosphoesterase, PA-phosphatase related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001172 252.0
HFD3_k127_5586140_2 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008542 245.0
HFD3_k127_5586140_3 Stress responsive A/B Barrel Domain - - - 0.000000000000008303 78.0
HFD3_k127_5588018_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 1.12e-199 638.0
HFD3_k127_5588018_1 Ferric reductase like transmembrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000155 238.0
HFD3_k127_5588018_2 VIT family - - - 0.000000000000000000000000000000000000000000000000000000001816 213.0
HFD3_k127_5588018_3 protein conserved in bacteria K09966 - - 0.0000000000000000000000000000000000000000000000000000007809 194.0
HFD3_k127_5588018_4 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000002111 194.0
HFD3_k127_5588018_5 Pfam:Pyridox_oxidase - - - 0.00000000000000000000000000000000006653 137.0
HFD3_k127_5588018_6 FMN_bind - - - 0.000000000000000001589 94.0
HFD3_k127_5605837_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 526.0
HFD3_k127_5605837_1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 520.0
HFD3_k127_5605837_2 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 492.0
HFD3_k127_5605837_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000003679 234.0
HFD3_k127_5605837_4 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000000000008434 182.0
HFD3_k127_5605837_5 Aldo/keto reductase family K18471 - - 0.000000000000000000000000000000000000000000000001013 186.0
HFD3_k127_5605837_6 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000004034 190.0
HFD3_k127_5605837_7 endonuclease activity - - - 0.0000000000000000000000000000000001281 137.0
HFD3_k127_5605837_8 2-phosphosulfolactate phosphatase activity K05979 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 0.00000000000000000000000000004023 126.0
HFD3_k127_562890_0 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004039 399.0
HFD3_k127_562890_1 Thioesterase K07107 - - 0.000000000000000000000000000000000000000000000000003203 185.0
HFD3_k127_562890_2 ATP-dependent Clp protease adaptor protein ClpS K06891 - - 0.00000000000000000000000000000000000005893 153.0
HFD3_k127_562890_5 - - - - 0.0008381 44.0
HFD3_k127_5638425_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.376e-295 919.0
HFD3_k127_5638425_1 acyl-CoA dehydrogenase - - - 1.029e-222 703.0
HFD3_k127_5638425_10 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 345.0
HFD3_k127_5638425_11 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 347.0
HFD3_k127_5638425_12 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 297.0
HFD3_k127_5638425_13 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 288.0
HFD3_k127_5638425_14 fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004985 292.0
HFD3_k127_5638425_15 PaaX-like protein K02616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002517 267.0
HFD3_k127_5638425_16 dTDP-4-dehydrorhamnose reductase activity K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000146 259.0
HFD3_k127_5638425_17 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000007203 233.0
HFD3_k127_5638425_18 - K09957 - - 0.000000000000000000000000000000000000000000000000000000000006083 229.0
HFD3_k127_5638425_19 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000002361 210.0
HFD3_k127_5638425_2 Putative modulator of DNA gyrase K03592 - - 7.62e-211 663.0
HFD3_k127_5638425_20 Methyltransferase - - - 0.000000000000000000000000000000000000000000000001689 182.0
HFD3_k127_5638425_21 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000001731 167.0
HFD3_k127_5638425_22 helix_turn_helix ASNC type K03718 - - 0.0000000000000000000000000000000008978 136.0
HFD3_k127_5638425_24 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.00000000000000000000000000000001068 132.0
HFD3_k127_5638425_25 Beta-Ig-H3 fasciclin - - - 0.00000000000000000000000000000004725 133.0
HFD3_k127_5638425_27 Regulatory protein, FmdB family - - - 0.000000000000000000001352 98.0
HFD3_k127_5638425_28 Putative adhesin - - - 0.00000000000000003797 91.0
HFD3_k127_5638425_29 PFAM regulatory protein LuxR - - - 0.0000000000000005206 93.0
HFD3_k127_5638425_3 Activates fatty acids by binding to coenzyme A K12429,K18662 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051087 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 557.0
HFD3_k127_5638425_30 Serine aminopeptidase, S33 - - - 0.00000000000002474 88.0
HFD3_k127_5638425_31 SnoaL-like domain - - - 0.000000000003758 79.0
HFD3_k127_5638425_32 protein encoded in hypervariable junctions of pilus gene clusters - - - 0.000000009471 64.0
HFD3_k127_5638425_33 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00002074 47.0
HFD3_k127_5638425_34 4-hydroxyphenylpyruvate dioxygenase K00457 - 1.13.11.27 0.00005348 53.0
HFD3_k127_5638425_4 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 494.0
HFD3_k127_5638425_5 Putative modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 490.0
HFD3_k127_5638425_6 AMP-binding enzyme K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 465.0
HFD3_k127_5638425_7 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005681 460.0
HFD3_k127_5638425_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008011 433.0
HFD3_k127_5638425_9 Nucleotidyl transferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 360.0
HFD3_k127_5655851_0 ABC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 578.0
HFD3_k127_5655851_1 protein conserved in bacteria K09927 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007111 463.0
HFD3_k127_5655851_10 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000002678 156.0
HFD3_k127_5655851_2 permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 454.0
HFD3_k127_5655851_3 carbohydrate transport K05813 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007245 379.0
HFD3_k127_5655851_5 PFAM binding-protein-dependent transport systems inner membrane component K05814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 342.0
HFD3_k127_5655851_6 Belongs to the ABC transporter superfamily K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 327.0
HFD3_k127_5655851_7 L-asparaginase II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 306.0
HFD3_k127_5655851_8 Binding-protein-dependent transport systems inner membrane component K02026,K05815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008628 290.0
HFD3_k127_5655851_9 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000003305 263.0
HFD3_k127_5671862_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 284.0
HFD3_k127_5671862_1 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001646 247.0
HFD3_k127_5671862_2 dioxygenase activity - - - 0.00000000000000000000000000000000000000000000000000002846 197.0
HFD3_k127_5671862_3 inositol monophosphate 1-phosphatase activity K01082,K01092 - 3.1.3.25,3.1.3.7 0.00000000000000000000000000000000000000000000000449 181.0
HFD3_k127_5671862_4 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000004001 143.0
HFD3_k127_5671862_5 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000003984 129.0
HFD3_k127_5671862_6 - - - - 0.000000000000000000000000000000007517 134.0
HFD3_k127_5671862_7 PFAM AIG2 family protein - - - 0.0000000000000000000000000000354 130.0
HFD3_k127_5673724_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1410.0
HFD3_k127_5673724_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 3.916e-263 816.0
HFD3_k127_5673724_10 Glycine cleavage T-protein C-terminal barrel domain K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 470.0
HFD3_k127_5673724_11 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0008652,GO:0008743,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030145,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046870,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 1.1.1.103 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 478.0
HFD3_k127_5673724_12 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 447.0
HFD3_k127_5673724_13 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 444.0
HFD3_k127_5673724_14 ribosomal rna small subunit methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 424.0
HFD3_k127_5673724_15 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004494 406.0
HFD3_k127_5673724_16 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007327 417.0
HFD3_k127_5673724_17 Enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 395.0
HFD3_k127_5673724_18 ATPases associated with a variety of cellular activities K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 395.0
HFD3_k127_5673724_19 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 393.0
HFD3_k127_5673724_2 Flavin containing amine oxidoreductase - - - 2.676e-245 787.0
HFD3_k127_5673724_20 Dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000511 378.0
HFD3_k127_5673724_21 Hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 366.0
HFD3_k127_5673724_22 TOBE domain K02017,K02018 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 367.0
HFD3_k127_5673724_23 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 365.0
HFD3_k127_5673724_24 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 358.0
HFD3_k127_5673724_25 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 357.0
HFD3_k127_5673724_26 Pyridoxal phosphate biosynthetic protein PdxA K22024 - 1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 352.0
HFD3_k127_5673724_27 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008245 311.0
HFD3_k127_5673724_28 Molybdate ABC transporter K02017,K02018 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 307.0
HFD3_k127_5673724_29 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 305.0
HFD3_k127_5673724_3 hydrogenase expression formation protein HypD K04654 - - 1.231e-209 655.0
HFD3_k127_5673724_30 Ankyrin repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009957 296.0
HFD3_k127_5673724_31 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000484 301.0
HFD3_k127_5673724_32 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000005319 237.0
HFD3_k127_5673724_33 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000001595 234.0
HFD3_k127_5673724_34 Protein of unknown function (DUF971) K00471 - 1.14.11.1 0.000000000000000000000000000000000000000000000000000000000002893 223.0
HFD3_k127_5673724_35 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000003037 224.0
HFD3_k127_5673724_36 PFAM globin K06886 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0015669,GO:0015671,GO:0015893,GO:0016020,GO:0019825,GO:0020037,GO:0036094,GO:0042221,GO:0042493,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051179,GO:0051234,GO:0071944,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000237 205.0
HFD3_k127_5673724_37 Diacylglycerol kinase K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000002896 211.0
HFD3_k127_5673724_38 Belongs to the serpin family K13963 - - 0.000000000000000000000000000000000000000000000000000003795 207.0
HFD3_k127_5673724_39 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000005905 186.0
HFD3_k127_5673724_4 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840 - 5.4.2.8 2.124e-209 659.0
HFD3_k127_5673724_40 YbaK prolyl-tRNA synthetase associated region - - - 0.0000000000000000000000000000000000000000000000153 189.0
HFD3_k127_5673724_41 Domain of Unknown Function (DUF1206) - - - 0.00000000000000000000000000000000000000000000005254 180.0
HFD3_k127_5673724_42 competence protein K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000006609 174.0
HFD3_k127_5673724_43 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000003437 176.0
HFD3_k127_5673724_44 Methyltransferase domain - - - 0.000000000000000000000000000000001516 139.0
HFD3_k127_5673724_45 Major facilitator superfamily - - - 0.000000000000000000000000000006511 135.0
HFD3_k127_5673724_46 PAP2 superfamily K19302 - 3.6.1.27 0.00000000000000000000000000001978 129.0
HFD3_k127_5673724_47 hydrogenase maturation factor K04653 - - 0.000000000000000000000001388 107.0
HFD3_k127_5673724_48 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.00000000000000000000000636 108.0
HFD3_k127_5673724_49 Putative nucleotide-binding of sugar-metabolising enzyme K22129 - 2.7.1.219,2.7.1.220 0.00000000000000000000006712 114.0
HFD3_k127_5673724_5 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008144,GO:0016874,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 556.0
HFD3_k127_5673724_50 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000007214 91.0
HFD3_k127_5673724_51 EamA-like transporter family - - - 0.00000002615 65.0
HFD3_k127_5673724_53 Belongs to the UPF0312 family - - - 0.00002651 53.0
HFD3_k127_5673724_6 Belongs to the enoyl-CoA hydratase isomerase family. MenB subfamily K01661 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0008935,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016043,GO:0016829,GO:0016830,GO:0016833,GO:0022607,GO:0034214,GO:0042180,GO:0042181,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:1901576,GO:1901661,GO:1901663 4.1.3.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 520.0
HFD3_k127_5673724_7 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 533.0
HFD3_k127_5673724_8 Phytanoyl-CoA dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 519.0
HFD3_k127_5673724_9 PhoD-like phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 486.0
HFD3_k127_5842522_0 Glycosyl transferases group 1 K13668 - 2.4.1.346 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 530.0
HFD3_k127_5842522_1 ROK family K00845,K00886 - 2.7.1.2,2.7.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 413.0
HFD3_k127_5842522_2 4Fe-4S double cluster binding domain K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007455 386.0
HFD3_k127_5842522_3 helix_turn _helix lactose operon repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 329.0
HFD3_k127_5842522_4 ABC transporter substrate-binding protein K02058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000385 286.0
HFD3_k127_5842522_5 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001156 263.0
HFD3_k127_5842522_6 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000000000000000003606 216.0
HFD3_k127_5842522_7 endonuclease activity - - - 0.0000000000000000000000000000000000302 143.0
HFD3_k127_5842522_8 - - - - 0.000000000000000000002107 106.0
HFD3_k127_5842522_9 - - - - 0.000008774 50.0
HFD3_k127_5872451_0 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 4.501e-232 737.0
HFD3_k127_5872451_1 Acetyl-CoA acetyltransferase K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000693 584.0
HFD3_k127_5872451_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 552.0
HFD3_k127_5872451_3 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006929 443.0
HFD3_k127_5872451_4 nucleoside hydrolase K01239,K01250,K10213 - 3.2.2.1,3.2.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 389.0
HFD3_k127_5872451_5 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 344.0
HFD3_k127_5872451_6 Methyltransferase small domain K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 306.0
HFD3_k127_5872451_7 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000008816 231.0
HFD3_k127_5872451_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000003017 235.0
HFD3_k127_5962864_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 2.7e-229 715.0
HFD3_k127_5962864_1 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007178 342.0
HFD3_k127_5962864_2 Major facilitator Superfamily - - - 0.00000000000000000000000000000004133 141.0
HFD3_k127_5972359_0 DNA segregation ATPase FtsK SpoIIIE and related K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004707 582.0
HFD3_k127_5972359_1 NADPH quinone reductase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 509.0
HFD3_k127_5972359_2 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 329.0
HFD3_k127_5972359_3 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006794 313.0
HFD3_k127_5972359_4 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009923 265.0
HFD3_k127_5972359_5 AAA ATPase domain - - - 0.000000000000000000000000000000000002903 143.0
HFD3_k127_5972359_6 - - - - 0.0000000000000000000000003317 115.0
HFD3_k127_5972359_7 - - - - 0.0000000000000007839 87.0
HFD3_k127_5972359_8 membrane protein (DUF2078) - - - 0.0000000004379 64.0
HFD3_k127_5972359_9 membrane protein (DUF2078) K08982 - - 0.00000003585 59.0
HFD3_k127_5990084_0 belongs to the sigma-70 factor family K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 534.0
HFD3_k127_5990084_1 Glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 547.0
HFD3_k127_5990084_10 resistance ABC transporter ATPase subunit K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006255 320.0
HFD3_k127_5990084_11 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004015 317.0
HFD3_k127_5990084_12 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001882 258.0
HFD3_k127_5990084_13 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001931 248.0
HFD3_k127_5990084_14 ABC-2 type transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000019 255.0
HFD3_k127_5990084_15 pyridoxamine 5'-phosphate K07005 - - 0.0000000000000000000000000000000000000000000000000000000000000000001369 235.0
HFD3_k127_5990084_16 Domain of unknown function (DUF4188) - - - 0.000000000000000000000000000000000000000000000000000000000000000006313 239.0
HFD3_k127_5990084_17 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000000000000000000000000000000006844 225.0
HFD3_k127_5990084_18 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000082 220.0
HFD3_k127_5990084_19 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000005075 177.0
HFD3_k127_5990084_2 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 512.0
HFD3_k127_5990084_20 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000002053 168.0
HFD3_k127_5990084_21 YCII-related domain - - - 0.000000000000000000000000000000000000000003658 161.0
HFD3_k127_5990084_22 Belongs to the peptidase S8 family K01173 - - 0.00000000000000000000000000000000000008836 162.0
HFD3_k127_5990084_23 PFAM response regulator receiver K07689 - - 0.00000000000000000000000000000002242 131.0
HFD3_k127_5990084_24 Histidine kinase - - - 0.0000000000000000000000000000009574 124.0
HFD3_k127_5990084_25 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.00000000000000000000000000000344 138.0
HFD3_k127_5990084_26 lipolytic protein G-D-S-L family - - - 0.00000000000000000000002303 116.0
HFD3_k127_5990084_27 Phage integrase family - - - 0.0000000006754 70.0
HFD3_k127_5990084_28 - - - - 0.000000001448 60.0
HFD3_k127_5990084_29 Carbamoyltransferase C-terminus K00612 - - 0.000000002986 61.0
HFD3_k127_5990084_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01652,K12673 - 2.2.1.6,2.5.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 430.0
HFD3_k127_5990084_4 Protein of unknown function (DUF3500) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 407.0
HFD3_k127_5990084_5 Taurine catabolism dioxygenase TauD, TfdA family K22303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 394.0
HFD3_k127_5990084_6 belongs to the sigma-70 factor family K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 398.0
HFD3_k127_5990084_7 PFAM glycosidase, PH1107-related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 390.0
HFD3_k127_5990084_8 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K19189 - 1.14.13.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 363.0
HFD3_k127_5990084_9 Predicted Permease Membrane Region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000588 327.0
HFD3_k127_5993052_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.872e-273 848.0
HFD3_k127_5993052_1 AAA domain - - - 1.513e-242 767.0
HFD3_k127_5993052_10 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - GO:0008150,GO:0010565,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0080090 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004058 507.0
HFD3_k127_5993052_11 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008058 510.0
HFD3_k127_5993052_12 Pirin K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 446.0
HFD3_k127_5993052_13 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 446.0
HFD3_k127_5993052_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004702 443.0
HFD3_k127_5993052_15 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 430.0
HFD3_k127_5993052_16 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 426.0
HFD3_k127_5993052_17 ABC transporter substrate-binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 434.0
HFD3_k127_5993052_18 PFAM ATPase associated with various cellular activities, AAA_5 K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 376.0
HFD3_k127_5993052_19 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000521 376.0
HFD3_k127_5993052_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.662e-241 755.0
HFD3_k127_5993052_20 alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 361.0
HFD3_k127_5993052_21 Glycosyl hydrolases family 18 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 367.0
HFD3_k127_5993052_22 Acyl CoA acetate 3-ketoacid CoA K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005244 317.0
HFD3_k127_5993052_23 tRNA threonylcarbamoyladenosine modification K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 317.0
HFD3_k127_5993052_24 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 319.0
HFD3_k127_5993052_25 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 317.0
HFD3_k127_5993052_26 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000911 310.0
HFD3_k127_5993052_27 TIGRFAM beta-ketoadipate pathway transcriptional regulators, PcaR PcaU PobR family K02624 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003045 286.0
HFD3_k127_5993052_28 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004934 278.0
HFD3_k127_5993052_29 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002446 290.0
HFD3_k127_5993052_3 synthetase K18688 - 6.2.1.42 1.278e-232 732.0
HFD3_k127_5993052_30 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005337 282.0
HFD3_k127_5993052_31 Belongs to the pirin family K06911 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002417 271.0
HFD3_k127_5993052_32 Protein containing von Willebrand factor type A (VWA) domain K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001929 285.0
HFD3_k127_5993052_33 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002989 276.0
HFD3_k127_5993052_34 ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001048 261.0
HFD3_k127_5993052_35 NlpC/P60 family K21471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004316 261.0
HFD3_k127_5993052_36 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000000000002483 242.0
HFD3_k127_5993052_37 subfamily IA, variant 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000004328 251.0
HFD3_k127_5993052_38 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K08234 - - 0.00000000000000000000000000000000000000000000000000000000000005647 229.0
HFD3_k127_5993052_39 ABC-2 type transporter - - - 0.0000000000000000000000000000000000000000000000000000000001408 218.0
HFD3_k127_5993052_4 Acetyl-coenzyme A synthetase N-terminus K01907 - 6.2.1.16 2.488e-219 698.0
HFD3_k127_5993052_40 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000454 209.0
HFD3_k127_5993052_41 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.000000000000000000000000000000000000000000000000000003234 198.0
HFD3_k127_5993052_42 nUDIX hydrolase - GO:0003674,GO:0003824,GO:0016787,GO:0016817,GO:0016818 - 0.0000000000000000000000000000000000000000000000009861 182.0
HFD3_k127_5993052_43 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000001569 177.0
HFD3_k127_5993052_44 COG0424 Nucleotide-binding protein implicated in inhibition of septum formation K06287 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0047429 - 0.0000000000000000000000000000000000000000001356 175.0
HFD3_k127_5993052_45 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000002464 165.0
HFD3_k127_5993052_46 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000001558 149.0
HFD3_k127_5993052_48 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000004705 109.0
HFD3_k127_5993052_49 Mycofactocin system - - - 0.00000000000000000000153 96.0
HFD3_k127_5993052_5 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 3.519e-211 664.0
HFD3_k127_5993052_50 Prokaryotic phospholipase A2 - - - 0.0000000000000000004295 93.0
HFD3_k127_5993052_51 Protein conserved in bacteria - - - 0.000000004168 67.0
HFD3_k127_5993052_6 NADH:flavin oxidoreductase / NADH oxidase family - - - 7.148e-200 640.0
HFD3_k127_5993052_7 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 601.0
HFD3_k127_5993052_8 Thiolase, C-terminal domain K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 530.0
HFD3_k127_5993052_9 Alcohol dehydrogenase GroES-like domain K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 517.0
HFD3_k127_6034448_0 AMP-binding enzyme C-terminal domain K18661 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005673 524.0
HFD3_k127_6034448_1 2-dehydropantoate 2-reductase K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 376.0
HFD3_k127_6034448_2 reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000217 239.0
HFD3_k127_6034448_3 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000007687 235.0
HFD3_k127_6034448_4 Transglycosylase associated protein - - - 0.0000000000000000000000000000008587 123.0
HFD3_k127_6071771_0 Heavy metal translocating P-type atpase K01533,K17686 - 3.6.3.4,3.6.3.54 1.554e-305 968.0
HFD3_k127_6071771_1 PFAM Uncharacterised BCR, COG1937 K21600 - - 0.00000000000000000000000000000007239 126.0
HFD3_k127_6082794_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.026e-253 799.0
HFD3_k127_6082794_1 Aminotransferase class-V K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008982 465.0
HFD3_k127_6082794_11 Branched-chain amino acid transport protein (AzlD) - - - 0.00000000000006282 75.0
HFD3_k127_6082794_2 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 462.0
HFD3_k127_6082794_3 tRNA methyl transferase K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 469.0
HFD3_k127_6082794_4 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 422.0
HFD3_k127_6082794_5 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 320.0
HFD3_k127_6082794_6 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000139 243.0
HFD3_k127_6082794_7 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000002911 215.0
HFD3_k127_6082794_8 - - - - 0.0000000000000000000000000000000000000000000000004666 187.0
HFD3_k127_6082794_9 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000001322 166.0
HFD3_k127_6088119_0 Phosphoglycerate kinase K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 560.0
HFD3_k127_6088119_1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 511.0
HFD3_k127_6088119_2 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006364 408.0
HFD3_k127_6088119_3 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 379.0
HFD3_k127_6088119_4 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000809 357.0
HFD3_k127_6088119_5 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 GO:0003674,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0017038,GO:0022857,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0033036,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043295,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0048037,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072341,GO:1900750,GO:1901681,GO:1904680 - 0.00000000000001902 81.0
HFD3_k127_6155239_0 KaiC K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005173 524.0
HFD3_k127_6155239_1 DisA bacterial checkpoint controller linker region K07067 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008807 413.0
HFD3_k127_6155239_2 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 289.0
HFD3_k127_6155239_3 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000002602 259.0
HFD3_k127_6155239_4 - - - - 0.0000000000000000000000000000000000000000000162 171.0
HFD3_k127_6155239_5 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000007517 157.0
HFD3_k127_6155239_6 amine dehydrogenase activity - - - 0.0000000000000000000000002937 119.0
HFD3_k127_6231369_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 522.0
HFD3_k127_6231369_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000191 251.0
HFD3_k127_6231369_2 Alpha beta hydrolase fold - - - 0.000000000000000000000000000000553 133.0
HFD3_k127_6231369_3 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000008263 130.0
HFD3_k127_6231369_4 Rhodanese Homology Domain - - - 0.0000000000000000000000000001823 119.0
HFD3_k127_6231369_5 Putative exonuclease SbcCD, C subunit - - - 0.000000000003382 69.0
HFD3_k127_6231369_6 - - - - 0.000000000004484 74.0
HFD3_k127_6231369_7 - - - - 0.0001367 53.0
HFD3_k127_6231369_8 hemerythrin HHE cation binding domain - - - 0.0009685 48.0
HFD3_k127_6280838_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 1.241e-232 726.0
HFD3_k127_6280838_1 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 6.701e-220 688.0
HFD3_k127_6280838_10 Enoyl-CoA hydratase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 376.0
HFD3_k127_6280838_11 cation diffusion facilitator family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 341.0
HFD3_k127_6280838_12 ABC transporter, periplasmic binding protein, thiB subfamily K02064 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 349.0
HFD3_k127_6280838_13 inositol monophosphatase K01092,K05602 - 3.1.3.15,3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 316.0
HFD3_k127_6280838_14 NifU-like domain K07400 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 297.0
HFD3_k127_6280838_15 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004513 294.0
HFD3_k127_6280838_16 ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006336 296.0
HFD3_k127_6280838_17 PAC2 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002114 280.0
HFD3_k127_6280838_18 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000181 254.0
HFD3_k127_6280838_19 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000000000000000000000000000000000000000000000000000625 252.0
HFD3_k127_6280838_2 Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004315 584.0
HFD3_k127_6280838_20 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001126 226.0
HFD3_k127_6280838_21 Belongs to the ABC transporter superfamily K02052,K02062 - - 0.0000000000000000000000000000000000000000000000000000000000000166 221.0
HFD3_k127_6280838_22 Cobinamide kinase / cobinamide phosphate guanyltransferase K02231 - 2.7.1.156,2.7.7.62 0.0000000000000000000000000000000000000000001088 166.0
HFD3_k127_6280838_23 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000007179 162.0
HFD3_k127_6280838_24 resistance protein CopC K14166 - - 0.000000000000000000000000000000000000001904 169.0
HFD3_k127_6280838_25 Mycothiol maleylpyruvate isomerase N-terminal domain K16163 - 5.2.1.4 0.000000000000000000000000000000000000003985 153.0
HFD3_k127_6280838_26 THIamine pyrophosphokinase K00949 - 2.7.6.2 0.000000000000000000000000000000000005372 144.0
HFD3_k127_6280838_27 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000019 120.0
HFD3_k127_6280838_28 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000001069 110.0
HFD3_k127_6280838_29 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.00000000001829 77.0
HFD3_k127_6280838_3 Cys/Met metabolism PLP-dependent enzyme K01739,K01740,K01761 - 2.5.1.48,2.5.1.49,4.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 531.0
HFD3_k127_6280838_30 universal stress protein - - - 0.00000000006684 71.0
HFD3_k127_6280838_4 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000681 530.0
HFD3_k127_6280838_5 ABC-type Fe3 transport system permease component K02011,K02063 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 490.0
HFD3_k127_6280838_6 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 451.0
HFD3_k127_6280838_7 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 452.0
HFD3_k127_6280838_8 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 422.0
HFD3_k127_6280838_9 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 403.0
HFD3_k127_6281589_0 Peptidase dimerisation domain - - - 8.34e-206 653.0
HFD3_k127_6281589_1 associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 486.0
HFD3_k127_6281589_10 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004095 290.0
HFD3_k127_6281589_11 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001364 250.0
HFD3_k127_6281589_12 tRNA processing K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002587 257.0
HFD3_k127_6281589_2 acyl-CoA dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 491.0
HFD3_k127_6281589_3 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004825 482.0
HFD3_k127_6281589_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 422.0
HFD3_k127_6281589_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 412.0
HFD3_k127_6281589_6 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 366.0
HFD3_k127_6281589_7 transport system, permease component K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 343.0
HFD3_k127_6281589_8 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009799 350.0
HFD3_k127_6281589_9 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 327.0
HFD3_k127_6315726_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 4.848e-197 627.0
HFD3_k127_6315726_1 UDP binding domain K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 530.0
HFD3_k127_6315726_10 - - - - 0.000000000000000000000000000000000000000000000000000000445 196.0
HFD3_k127_6315726_11 MDMPI C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000005057 204.0
HFD3_k127_6315726_12 Acyltransferase family - - - 0.00000000000000000000000000000000000000000011 174.0
HFD3_k127_6315726_13 PIN domain K07064 - - 0.0000000000000000000000000000000000000000002297 167.0
HFD3_k127_6315726_15 Domain of unknown function (DUF4389) - - - 0.0000000000000000000000000001582 124.0
HFD3_k127_6315726_16 -acetyltransferase - - - 0.0000000000000000006569 97.0
HFD3_k127_6315726_17 CHRD domain - - - 0.0000000000000000009604 97.0
HFD3_k127_6315726_18 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family K11717 - 2.8.1.7,4.4.1.16 0.00000000000005711 74.0
HFD3_k127_6315726_19 positive regulation of growth - - - 0.0000000000005929 78.0
HFD3_k127_6315726_2 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784,K12448 - 5.1.3.2,5.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 415.0
HFD3_k127_6315726_22 TIGRFAM conserved repeat domain - - - 0.0000009986 60.0
HFD3_k127_6315726_3 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007009 399.0
HFD3_k127_6315726_4 3-beta hydroxysteroid dehydrogenase/isomerase family K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 382.0
HFD3_k127_6315726_5 thiolester hydrolase activity K01990,K06889 GO:0008150,GO:0009987,GO:0051301 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 353.0
HFD3_k127_6315726_6 unsaturated fatty acid biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 335.0
HFD3_k127_6315726_7 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 323.0
HFD3_k127_6315726_8 FeS assembly ATPase SufC K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 315.0
HFD3_k127_6315726_9 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004369 251.0
HFD3_k127_6352195_0 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008467 609.0
HFD3_k127_6352195_1 MMPL family K06994 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008071 554.0
HFD3_k127_6352195_2 COG0457 FOG TPR repeat - - - 0.0004237 48.0
HFD3_k127_6400184_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 2.453e-202 642.0
HFD3_k127_6400184_10 ABC-type multidrug transport system, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 351.0
HFD3_k127_6400184_11 Pfam:Pyridox_oxidase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 332.0
HFD3_k127_6400184_12 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain - GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0019627,GO:0034641,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005967 321.0
HFD3_k127_6400184_13 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000001151 272.0
HFD3_k127_6400184_14 Domain present in PSD-95, Dlg, and ZO-1/2. K08372 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001645 269.0
HFD3_k127_6400184_15 Permeases of the drug metabolite transporter DMT superfamily K15269 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002347 249.0
HFD3_k127_6400184_16 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003047 259.0
HFD3_k127_6400184_17 Transcriptional regulator sugar kinase K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000001634 244.0
HFD3_k127_6400184_18 Evidence 2b Function of strongly homologous gene K02282 - - 0.00000000000000000000000000000000000000000000000000000000000004071 237.0
HFD3_k127_6400184_19 Type ii secretion system K12510 - - 0.00000000000000000000000000000000000000000000000000000000000004735 244.0
HFD3_k127_6400184_2 Type II/IV secretion system protein K02283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 524.0
HFD3_k127_6400184_20 stress protein (general stress protein 26) - - - 0.00000000000000000000000000000000000000000000000000000000005375 209.0
HFD3_k127_6400184_21 EVE domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000007555 203.0
HFD3_k127_6400184_22 Precorrin-8x methylmutase - - - 0.000000000000000000000000000000000000000000000000000001128 203.0
HFD3_k127_6400184_23 molybdopterin cofactor binding - - - 0.0000000000000000000000000000000000000000000000000004023 192.0
HFD3_k127_6400184_24 Type ii secretion system K12511 - - 0.00000000000000000000000000000000000000000000000001201 196.0
HFD3_k127_6400184_25 MarR family - - - 0.00000000000000000000000000000000000000000000009769 173.0
HFD3_k127_6400184_26 PFAM Short-chain dehydrogenase reductase SDR K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000009139 166.0
HFD3_k127_6400184_27 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000000000000000000000000000003583 153.0
HFD3_k127_6400184_28 Pilus assembly protein K02279 - - 0.000000000000000000000000000000001425 140.0
HFD3_k127_6400184_29 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K15520 - 2.3.1.189 0.00000000000000000000000002037 114.0
HFD3_k127_6400184_3 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 508.0
HFD3_k127_6400184_30 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000003627 111.0
HFD3_k127_6400184_31 GDSL-like Lipase/Acylhydrolase - - - 0.000000000006326 76.0
HFD3_k127_6400184_32 TadE-like protein - - - 0.00000001548 62.0
HFD3_k127_6400184_33 aspartic-type endopeptidase activity K02654 - 3.4.23.43 0.00000001672 60.0
HFD3_k127_6400184_34 Flp Fap pilin component K02651 - - 0.00000004477 57.0
HFD3_k127_6400184_35 pyridoxamine 5-phosphate - - - 0.000000338 58.0
HFD3_k127_6400184_4 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004594 470.0
HFD3_k127_6400184_5 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 435.0
HFD3_k127_6400184_6 Domain of unknown function (DUF4389) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 421.0
HFD3_k127_6400184_7 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008524 402.0
HFD3_k127_6400184_8 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 367.0
HFD3_k127_6400184_9 ABC-2 family transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000425 366.0
HFD3_k127_6406130_0 Proline dehydrogenase K13821 - 1.2.1.88,1.5.5.2 6.476e-318 999.0
HFD3_k127_6406130_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 4.718e-245 764.0
HFD3_k127_6406130_2 AMP-binding enzyme C-terminal domain - - - 8.756e-242 758.0
HFD3_k127_6406130_3 DEAD-like helicases superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 537.0
HFD3_k127_6406130_4 Saccharopine dehydrogenase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 424.0
HFD3_k127_6406130_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 312.0
HFD3_k127_6406130_6 Peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000002036 233.0
HFD3_k127_6406130_7 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000000000000000000000000000000693 228.0
HFD3_k127_6439600_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 3.655e-232 728.0
HFD3_k127_6439600_1 Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006937 589.0
HFD3_k127_6439600_10 FR47-like protein - - - 0.00000000000000001332 88.0
HFD3_k127_6439600_11 Putative zinc-finger - - - 0.00000000001505 67.0
HFD3_k127_6439600_12 Glycogen debranching enzyme N terminal - - - 0.00000005565 55.0
HFD3_k127_6439600_2 Nitrite and sulphite reductase 4Fe-4S domain K00362,K00366,K00381,K00392 - 1.7.1.15,1.7.7.1,1.8.1.2,1.8.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006807 457.0
HFD3_k127_6439600_3 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008896 439.0
HFD3_k127_6439600_4 Helix-turn-helix domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007172 341.0
HFD3_k127_6439600_5 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004664 315.0
HFD3_k127_6439600_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000134 224.0
HFD3_k127_6439600_7 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000005057 204.0
HFD3_k127_6439600_8 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000002241 169.0
HFD3_k127_6439600_9 Domain of unknown function (DUF4202) - - - 0.00000000000000000000000000000000000000002192 162.0
HFD3_k127_6506205_0 TOBE domain K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004138 433.0
HFD3_k127_6506205_1 PFAM extracellular solute-binding protein family 1 K02055,K11069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007872 369.0
HFD3_k127_6506205_2 Binding-protein-dependent transport system inner membrane component K11071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000012 279.0
HFD3_k127_6506205_3 Binding-protein-dependent transport system inner membrane component K11070,K11074 - - 0.0000000000000155 84.0
HFD3_k127_6511149_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.892e-281 894.0
HFD3_k127_6511149_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 498.0
HFD3_k127_6511149_10 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000008123 96.0
HFD3_k127_6511149_11 Protein of unknown function (DUF503) K09764 - - 0.000000000000002394 81.0
HFD3_k127_6511149_12 Protein of unknown function (DUF448) K07742 - - 0.0000000003384 66.0
HFD3_k127_6511149_13 Chorismate mutase type II K04092 - 5.4.99.5 0.0000000005397 69.0
HFD3_k127_6511149_2 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007055 436.0
HFD3_k127_6511149_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 341.0
HFD3_k127_6511149_4 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006256 311.0
HFD3_k127_6511149_5 NMT1/THI5 like K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 314.0
HFD3_k127_6511149_6 DSBA oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002435 238.0
HFD3_k127_6511149_7 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000001247 215.0
HFD3_k127_6511149_8 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000000004633 151.0
HFD3_k127_6511149_9 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000004219 127.0
HFD3_k127_6516467_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 3.112e-251 784.0
HFD3_k127_6516467_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 2.039e-211 672.0
HFD3_k127_6516467_10 Rhomboid family K19225 - 3.4.21.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001487 274.0
HFD3_k127_6516467_11 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001019 256.0
HFD3_k127_6516467_12 Domain of unknown function (DUF1731) K07071 GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006066,GO:0006629,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008395,GO:0009056,GO:0016020,GO:0016042,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016709,GO:0020037,GO:0030312,GO:0031073,GO:0036199,GO:0044238,GO:0044281,GO:0044282,GO:0044464,GO:0046164,GO:0046906,GO:0048037,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1901615,GO:1901616,GO:1902652 - 0.0000000000000000000000000000000000000000000000000000000001234 210.0
HFD3_k127_6516467_13 - - - - 0.0000000000000000000000000003599 132.0
HFD3_k127_6516467_2 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 1.05e-210 666.0
HFD3_k127_6516467_3 e3 binding domain K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006619 573.0
HFD3_k127_6516467_4 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004772 555.0
HFD3_k127_6516467_5 Creatinase/Prolidase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 516.0
HFD3_k127_6516467_6 DNA polymerase LigD polymerase domain K01971,K10747 GO:0000166,GO:0000287,GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0003909,GO:0003910,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0004652,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006269,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016874,GO:0016886,GO:0016895,GO:0017076,GO:0018130,GO:0019438,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0033554,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070566,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0097747,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006769 432.0
HFD3_k127_6516467_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 387.0
HFD3_k127_6516467_8 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050790,GO:0050896,GO:0051340,GO:0051351,GO:0051716,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 377.0
HFD3_k127_6516467_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 348.0
HFD3_k127_6534229_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1163.0
HFD3_k127_6534229_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 2.742e-218 692.0
HFD3_k127_6534229_2 Phosphoadenosine phosphosulfate reductase family K00957 GO:0000103,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:1902494,GO:1902503,GO:1990234 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 430.0
HFD3_k127_6534229_3 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006793,GO:0006796,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:0071944,GO:1902494,GO:1902503,GO:1990234 2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 405.0
HFD3_k127_6534229_4 Acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 346.0
HFD3_k127_6534229_5 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000039 318.0
HFD3_k127_6534229_6 Tetrapyrrole (Corrin/Porphyrin) Methylases K02303,K13542 - 2.1.1.107,4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004707 295.0
HFD3_k127_6534229_7 of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000001916 224.0
HFD3_k127_6534229_8 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000006058 216.0
HFD3_k127_6534229_9 TIGRFAM siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.0000000000000000000000000000000000000000000001428 173.0
HFD3_k127_661686_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1241.0
HFD3_k127_661686_1 Glycosyl hydrolase 36 superfamily, catalytic domain K00702 - 2.4.1.20 0.0 1241.0
HFD3_k127_661686_10 Ecdysteroid kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004551 425.0
HFD3_k127_661686_11 ABC transporter K10543 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005975,GO:0005996,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0015749,GO:0015750,GO:0015753,GO:0019321,GO:0030246,GO:0030288,GO:0030313,GO:0031975,GO:0034219,GO:0036094,GO:0042597,GO:0042732,GO:0044238,GO:0044281,GO:0044464,GO:0048029,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005209 407.0
HFD3_k127_661686_12 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005831 406.0
HFD3_k127_661686_13 Ornithine cyclodeaminase/mu-crystallin family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005376 386.0
HFD3_k127_661686_14 Polysaccharide deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000835 368.0
HFD3_k127_661686_15 ATPases associated with a variety of cellular activities K10545 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 350.0
HFD3_k127_661686_16 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 342.0
HFD3_k127_661686_17 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 325.0
HFD3_k127_661686_18 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 302.0
HFD3_k127_661686_19 electron transport chain K00347,K03614,K21163 - 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 311.0
HFD3_k127_661686_2 FAD dependent oxidoreductase central domain - - - 2.091e-283 894.0
HFD3_k127_661686_20 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007342 276.0
HFD3_k127_661686_21 bifunctional deaminase-reductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001008 271.0
HFD3_k127_661686_22 6-phosphogluconolactonase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005045 271.0
HFD3_k127_661686_23 PFAM Uracil-DNA glycosylase superfamily K03649 - 3.2.2.28 0.00000000000000000000000000000000000000000000000000000000000000001379 230.0
HFD3_k127_661686_24 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000000000000000000000006618 214.0
HFD3_k127_661686_25 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.00000000000000000000000000000000000000000000000000000002802 204.0
HFD3_k127_661686_26 Ferric uptake regulator family K22297 - - 0.00000000000000000000000000000000000000000000000000000009264 202.0
HFD3_k127_661686_27 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000001243 197.0
HFD3_k127_661686_28 PFAM OsmC family protein K04063 - - 0.000000000000000000000000000000000000000000000000000005116 199.0
HFD3_k127_661686_29 transcriptional regulator K03566 - - 0.000000000000000000000000000000000000000000000000000005954 202.0
HFD3_k127_661686_3 Belongs to the IlvD Edd family K01687 - 4.2.1.9 7.818e-280 872.0
HFD3_k127_661686_30 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000002191 186.0
HFD3_k127_661686_31 oxidoreductase activity K00274 - 1.4.3.4 0.0000000000000000000000000000000000000000000000001121 196.0
HFD3_k127_661686_32 PFAM Rhomboid family - - - 0.0000000000000000000000000000000000000000000000001398 186.0
HFD3_k127_661686_33 DNA synthesis involved in DNA repair - - - 0.000000000000000000000000000000000000000000000003295 183.0
HFD3_k127_661686_34 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000005446 187.0
HFD3_k127_661686_35 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000002438 185.0
HFD3_k127_661686_36 glyoxalase III activity - - - 0.0000000000000000000000000000000000000264 155.0
HFD3_k127_661686_37 - - - - 0.0000000000000000000000000000004783 129.0
HFD3_k127_661686_38 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000002121 124.0
HFD3_k127_661686_39 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000001275 110.0
HFD3_k127_661686_4 Dehydrogenase K00467 - 1.13.12.4 2.266e-200 630.0
HFD3_k127_661686_40 DUF167 K09131 - - 0.000000000001102 75.0
HFD3_k127_661686_41 Baseplate assembly protein - - - 0.000000000001642 75.0
HFD3_k127_661686_42 Baseplate assembly protein - - - 0.00000000008949 70.0
HFD3_k127_661686_43 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.0000000004902 69.0
HFD3_k127_661686_45 Domain of unknown function (DUF4157) K02689,K02690 - - 0.000001487 57.0
HFD3_k127_661686_5 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 625.0
HFD3_k127_661686_6 belongs to the thioredoxin family K20543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 571.0
HFD3_k127_661686_7 FAD dependent oxidoreductase central domain K19191 - 1.5.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 501.0
HFD3_k127_661686_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 496.0
HFD3_k127_661686_9 Branched-chain amino acid transport system / permease component K10544 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004408 437.0
HFD3_k127_6620742_0 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 322.0
HFD3_k127_6620742_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003887 287.0
HFD3_k127_6620742_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000001437 197.0
HFD3_k127_6620742_3 Domain of unknown function (DUF222) - - - 0.000000000000000000000000000000000000002065 158.0
HFD3_k127_6620742_6 Peptidase C14 caspase catalytic subunit p20 - - - 0.00008835 54.0
HFD3_k127_6654590_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008851 316.0
HFD3_k127_6654590_1 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003188 279.0
HFD3_k127_6654590_2 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001738 269.0
HFD3_k127_6654590_3 PFAM Sporulation and spore germination - - - 0.0000000000068 76.0
HFD3_k127_6888594_0 FAD dependent oxidoreductase central domain - - - 0.0 1320.0
HFD3_k127_6888594_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372,K02567 - - 0.0 1186.0
HFD3_k127_6888594_10 Pfam Sulfatase - - - 6.348e-210 671.0
HFD3_k127_6888594_100 FCD - - - 0.0000000000000000000000000000000000000000003706 170.0
HFD3_k127_6888594_101 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000005723 169.0
HFD3_k127_6888594_102 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000000000000000001535 157.0
HFD3_k127_6888594_103 Acid phosphatase homologues K06153,K19302 - 3.6.1.27 0.000000000000000000000000000000000000000005902 162.0
HFD3_k127_6888594_104 Haem-degrading - - - 0.00000000000000000000000000000000000000001253 166.0
HFD3_k127_6888594_105 Dehydrogenase reductase sdr K00059 - 1.1.1.100 0.00000000000000000000000000000000000000003099 164.0
HFD3_k127_6888594_106 Family of unknown function (DUF5317) - - - 0.0000000000000000000000000000000000000002608 164.0
HFD3_k127_6888594_107 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000002699 161.0
HFD3_k127_6888594_108 Electron transfer flavoprotein, beta subunit FixA family protein K03521 - - 0.0000000000000000000000000000000000000003644 169.0
HFD3_k127_6888594_109 FCD - - - 0.0000000000000000000000000000000000000004399 156.0
HFD3_k127_6888594_11 ClpX C4-type zinc finger K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030312,GO:0030554,GO:0031333,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0044087,GO:0044238,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 6.424e-206 647.0
HFD3_k127_6888594_110 ornithine cyclodeaminase K01750 - 4.3.1.12 0.000000000000000000000000000000000000001452 162.0
HFD3_k127_6888594_111 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.00000000000000000000000000000000000002287 154.0
HFD3_k127_6888594_112 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.00000000000000000000000000000000000002716 154.0
HFD3_k127_6888594_113 - K03571 - - 0.00000000000000000000000000000000000006516 149.0
HFD3_k127_6888594_114 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000002743 151.0
HFD3_k127_6888594_115 - - - - 0.0000000000000000000000000000000000009176 147.0
HFD3_k127_6888594_116 COG0666 FOG Ankyrin repeat - - - 0.000000000000000000000000000000000002194 149.0
HFD3_k127_6888594_117 SnoaL-like domain - - - 0.000000000000000000000000000000000003999 150.0
HFD3_k127_6888594_118 Endonuclease Exonuclease Phosphatase - - - 0.000000000000000000000000000000000005357 146.0
HFD3_k127_6888594_119 Protein of unknown function (DUF1211) - - - 0.0000000000000000000000000000000000187 156.0
HFD3_k127_6888594_12 Rieske [2Fe-2S] domain K15762 - - 9.774e-206 655.0
HFD3_k127_6888594_120 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000006382 141.0
HFD3_k127_6888594_121 Ribosomal L27 protein K02899 - - 0.000000000000000000000000000000006321 135.0
HFD3_k127_6888594_122 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000002132 130.0
HFD3_k127_6888594_124 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000005739 123.0
HFD3_k127_6888594_125 acetyltransferase - - - 0.000000000000000000000000002059 120.0
HFD3_k127_6888594_126 Metal-sensitive transcriptional repressor - - - 0.00000000000000000000000002156 113.0
HFD3_k127_6888594_127 Rieske-like [2Fe-2S] domain K00363 - 1.7.1.15 0.00000000000000000000000005984 120.0
HFD3_k127_6888594_128 lactoylglutathione lyase activity - - - 0.00000000000000000000000008996 110.0
HFD3_k127_6888594_129 peroxiredoxin activity K03386,K03564 - 1.11.1.15 0.0000000000000000000000001324 109.0
HFD3_k127_6888594_13 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 1.156e-200 656.0
HFD3_k127_6888594_130 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000001621 109.0
HFD3_k127_6888594_131 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000571 106.0
HFD3_k127_6888594_132 NlpC/P60 family - - - 0.0000000000000000000007953 108.0
HFD3_k127_6888594_133 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.00000000000000000001271 97.0
HFD3_k127_6888594_134 - - - - 0.00000000000000000003399 97.0
HFD3_k127_6888594_135 domain protein - - - 0.0000000000000005022 91.0
HFD3_k127_6888594_136 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000152 82.0
HFD3_k127_6888594_137 Major Facilitator Superfamily K19577 - - 0.000000000008747 77.0
HFD3_k127_6888594_138 bacterioferritin comigratory protein K03564 - 1.11.1.15 0.00000000001198 65.0
HFD3_k127_6888594_139 60 kDa lysophospholipase K13278 GO:0003674,GO:0003824,GO:0003847,GO:0004067,GO:0004620,GO:0004622,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006530,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009066,GO:0009068,GO:0009987,GO:0016053,GO:0016054,GO:0016298,GO:0016787,GO:0016788,GO:0016810,GO:0016811,GO:0019637,GO:0019752,GO:0032787,GO:0034641,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0052689,GO:0071704,GO:0072329,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 3.1.1.47,3.1.1.5,3.5.1.1 0.000000009845 66.0
HFD3_k127_6888594_14 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 2.775e-200 637.0
HFD3_k127_6888594_140 Phosphotransferase enzyme family - - - 0.00000004957 66.0
HFD3_k127_6888594_141 FAD binding domain - - - 0.00000008285 55.0
HFD3_k127_6888594_142 Nucleotidyltransferase domain - - - 0.0000001154 60.0
HFD3_k127_6888594_143 EamA-like transporter family - - - 0.0000001381 63.0
HFD3_k127_6888594_144 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00001808 57.0
HFD3_k127_6888594_15 Cell division protein FtsA K03569 - - 2.486e-199 623.0
HFD3_k127_6888594_16 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 574.0
HFD3_k127_6888594_17 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 565.0
HFD3_k127_6888594_18 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 544.0
HFD3_k127_6888594_19 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007855 539.0
HFD3_k127_6888594_2 ATPase P-type (Transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1031.0
HFD3_k127_6888594_20 Polysaccharide biosynthesis C-terminal domain K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 520.0
HFD3_k127_6888594_21 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009052 520.0
HFD3_k127_6888594_22 Serine hydroxymethyltransferase K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 523.0
HFD3_k127_6888594_23 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 509.0
HFD3_k127_6888594_24 Belongs to the arginase family K12255 - 3.5.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003971 483.0
HFD3_k127_6888594_25 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 486.0
HFD3_k127_6888594_26 AAA domain (dynein-related subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005212 467.0
HFD3_k127_6888594_27 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 473.0
HFD3_k127_6888594_28 Phosphohydrolase-associated domain K01129 - 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 464.0
HFD3_k127_6888594_29 Belongs to the aldehyde dehydrogenase family K22187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 471.0
HFD3_k127_6888594_3 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 GO:0000287,GO:0003674,GO:0003824,GO:0004474,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0016054,GO:0016740,GO:0016746,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0046395,GO:0046487,GO:0046872,GO:0046912,GO:0071704,GO:0072329,GO:1901575 2.3.3.9 1.699e-310 967.0
HFD3_k127_6888594_30 Acetamidase/Formamidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008936 458.0
HFD3_k127_6888594_31 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003422 453.0
HFD3_k127_6888594_32 Oligopeptide/dipeptide transporter, C-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 442.0
HFD3_k127_6888594_33 nitrite transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007288 440.0
HFD3_k127_6888594_34 Cell cycle protein K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005024 440.0
HFD3_k127_6888594_35 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 439.0
HFD3_k127_6888594_36 VWA domain containing CoxE-like protein K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005596 431.0
HFD3_k127_6888594_37 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 450.0
HFD3_k127_6888594_38 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 425.0
HFD3_k127_6888594_39 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 429.0
HFD3_k127_6888594_4 PA domain - - - 5.169e-306 970.0
HFD3_k127_6888594_40 C4-dicarboxylate transporter malic acid transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006568 423.0
HFD3_k127_6888594_41 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000794 420.0
HFD3_k127_6888594_42 Iron-containing redox enzyme K06137 - 1.3.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 397.0
HFD3_k127_6888594_43 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 402.0
HFD3_k127_6888594_44 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004974 412.0
HFD3_k127_6888594_45 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007129 404.0
HFD3_k127_6888594_46 decarboxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 398.0
HFD3_k127_6888594_47 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004929 409.0
HFD3_k127_6888594_48 metal-dependent hydrolase of the TIM-barrel fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 394.0
HFD3_k127_6888594_49 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 398.0
HFD3_k127_6888594_5 Bacterial transcriptional activator domain - - - 1.827e-284 907.0
HFD3_k127_6888594_50 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005408 401.0
HFD3_k127_6888594_51 FAD dependent oxidoreductase K19746 - 1.4.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003934 379.0
HFD3_k127_6888594_52 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 376.0
HFD3_k127_6888594_53 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 364.0
HFD3_k127_6888594_54 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 349.0
HFD3_k127_6888594_55 Cation efflux family K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 355.0
HFD3_k127_6888594_56 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008814 328.0
HFD3_k127_6888594_57 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006203 353.0
HFD3_k127_6888594_58 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007476 323.0
HFD3_k127_6888594_59 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 320.0
HFD3_k127_6888594_6 Aminotransferase class-V - - - 4.263e-273 849.0
HFD3_k127_6888594_60 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 322.0
HFD3_k127_6888594_61 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 321.0
HFD3_k127_6888594_62 PFAM Methionine synthase, vitamin-B12 independent K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 319.0
HFD3_k127_6888594_63 Phage shock protein A K03969 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 310.0
HFD3_k127_6888594_64 CarD-like/TRCF domain K07736 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 300.0
HFD3_k127_6888594_65 FAD dependent oxidoreductase K19746 - 1.4.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 314.0
HFD3_k127_6888594_66 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 296.0
HFD3_k127_6888594_67 Belongs to the DapB family K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006038 286.0
HFD3_k127_6888594_68 Beta-eliminating lyase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002392 299.0
HFD3_k127_6888594_69 Cys/Met metabolism PLP-dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007718 292.0
HFD3_k127_6888594_7 Ribonuclease E/G family K08300,K08301 - 3.1.26.12 1.599e-237 749.0
HFD3_k127_6888594_70 Zinc permease K07238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004606 281.0
HFD3_k127_6888594_71 COG0657 Esterase lipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008769 279.0
HFD3_k127_6888594_72 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001859 293.0
HFD3_k127_6888594_73 PFAM Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002268 302.0
HFD3_k127_6888594_74 Binding-protein-dependent transport system inner membrane component K02038 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000112 280.0
HFD3_k127_6888594_75 HD phosphohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002036 262.0
HFD3_k127_6888594_76 phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases large terminal subunit K00479,K00499 - 1.14.15.7 0.00000000000000000000000000000000000000000000000000000000000000000000000003116 262.0
HFD3_k127_6888594_77 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001572 270.0
HFD3_k127_6888594_78 electron transfer flavoprotein K03522,K22432 - 1.3.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000001497 268.0
HFD3_k127_6888594_79 Inosine-uridine preferring nucleoside hydrolase K01240 - 3.2.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000302 257.0
HFD3_k127_6888594_8 Glucose inhibited division protein A - - - 1.041e-230 723.0
HFD3_k127_6888594_80 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000006019 245.0
HFD3_k127_6888594_81 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000001891 238.0
HFD3_k127_6888594_82 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000001996 233.0
HFD3_k127_6888594_83 Sulfite exporter TauE/SafE - - - 0.0000000000000000000000000000000000000000000000000000000000000000003891 238.0
HFD3_k127_6888594_84 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000002963 213.0
HFD3_k127_6888594_85 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000004678 217.0
HFD3_k127_6888594_86 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000001981 207.0
HFD3_k127_6888594_87 MerR, DNA binding K13639 - - 0.00000000000000000000000000000000000000000000000000000008774 198.0
HFD3_k127_6888594_88 PFAM Methionine sulfoxide reductase B K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000009501 194.0
HFD3_k127_6888594_89 oxidation-reduction process K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000000000003226 194.0
HFD3_k127_6888594_9 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 5.998e-220 707.0
HFD3_k127_6888594_90 PFAM Plasmid pRiA4b ORF-3-like protein - - - 0.00000000000000000000000000000000000000000000000000009393 194.0
HFD3_k127_6888594_91 Competence-damaged protein K03742 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000129 190.0
HFD3_k127_6888594_92 homocysteine K00547 - 2.1.1.10 0.0000000000000000000000000000000000000000000000000966 191.0
HFD3_k127_6888594_93 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000001409 179.0
HFD3_k127_6888594_94 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000001681 184.0
HFD3_k127_6888594_95 Protein of unknown function (DUF1003) - - - 0.00000000000000000000000000000000000000000000005707 178.0
HFD3_k127_6888594_96 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000002544 181.0
HFD3_k127_6888594_97 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000006635 171.0
HFD3_k127_6888594_98 Luciferase-like monooxygenase K15854 - 1.14.14.3 0.00000000000000000000000000000000000000000007906 173.0
HFD3_k127_6888594_99 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000001108 162.0
HFD3_k127_690479_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 0.0 1116.0
HFD3_k127_690479_1 ATPase family associated with various cellular activities (AAA) K01338 - 3.4.21.53 2.1e-322 1008.0
HFD3_k127_690479_10 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008751 561.0
HFD3_k127_690479_11 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000078 561.0
HFD3_k127_690479_12 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005797 539.0
HFD3_k127_690479_13 Luciferase-like monooxygenase K14733 - 1.14.13.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007185 531.0
HFD3_k127_690479_14 Penicillin binding protein transpeptidase domain K05364 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 534.0
HFD3_k127_690479_15 DNA polymerase III beta subunit K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007808 492.0
HFD3_k127_690479_16 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 462.0
HFD3_k127_690479_17 Cellulose biosynthesis protein BcsQ K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 443.0
HFD3_k127_690479_18 Reductase C-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007139 432.0
HFD3_k127_690479_19 trisaccharide binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 447.0
HFD3_k127_690479_2 Molybdopterin oxidoreductase Fe4S4 domain - - - 2.643e-301 937.0
HFD3_k127_690479_20 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 449.0
HFD3_k127_690479_21 Uncharacterised protein, DegV family COG1307 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 359.0
HFD3_k127_690479_22 Pectinacetylesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005205 372.0
HFD3_k127_690479_23 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 351.0
HFD3_k127_690479_24 6-phosphogluconolactonase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 336.0
HFD3_k127_690479_25 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009175 330.0
HFD3_k127_690479_26 60Kd inner membrane protein K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 327.0
HFD3_k127_690479_27 carboxylic ester hydrolase activity K01259,K19311 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 297.0
HFD3_k127_690479_28 Peptidase C26 K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 288.0
HFD3_k127_690479_29 Arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008502 304.0
HFD3_k127_690479_3 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 3.634e-259 813.0
HFD3_k127_690479_30 Aminotransferase class-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002495 291.0
HFD3_k127_690479_31 Protein of unknown function (DUF2662) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000163 280.0
HFD3_k127_690479_32 ParB-like nuclease domain K03497 GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005694,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0060187,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001427 278.0
HFD3_k127_690479_33 Putative single-stranded nucleic acids-binding domain K06346 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006143 257.0
HFD3_k127_690479_34 Saccharopine dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003617 257.0
HFD3_k127_690479_35 Sigma factor PP2C-like phosphatases K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000009689 257.0
HFD3_k127_690479_36 SpoU rRNA Methylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002083 251.0
HFD3_k127_690479_37 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009296 259.0
HFD3_k127_690479_38 Putative peptidoglycan binding domain K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000001485 252.0
HFD3_k127_690479_39 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000008086 236.0
HFD3_k127_690479_4 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 1.028e-222 702.0
HFD3_k127_690479_40 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000001311 238.0
HFD3_k127_690479_41 hydratase K02509 - - 0.00000000000000000000000000000000000000000000000000000000000000002185 232.0
HFD3_k127_690479_42 Serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000036 229.0
HFD3_k127_690479_43 2OG-Fe(II) oxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000008851 213.0
HFD3_k127_690479_44 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000177 206.0
HFD3_k127_690479_45 Single-strand binding protein family K03111 - - 0.0000000000000000000000000000000000000000000000000000004049 201.0
HFD3_k127_690479_46 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000006958 194.0
HFD3_k127_690479_48 Family of unknown function (DUF5318) - - - 0.00000000000000000000000000000000000000000000001835 173.0
HFD3_k127_690479_49 methyltransferase - - - 0.000000000000000000000000000000000000000000405 166.0
HFD3_k127_690479_5 AMP-binding enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 621.0
HFD3_k127_690479_50 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000006446 171.0
HFD3_k127_690479_51 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000000000000000000001983 159.0
HFD3_k127_690479_52 membrane - - - 0.00000000000000000000000000000000000000001365 162.0
HFD3_k127_690479_53 Forkhead associated domain - - - 0.00000000000000000000000000000000000000025 159.0
HFD3_k127_690479_54 - - - - 0.000000000000000000000000000000000000005151 150.0
HFD3_k127_690479_55 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009055,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0015037,GO:0015038,GO:0016020,GO:0016209,GO:0016491,GO:0016651,GO:0016657,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0022900,GO:0030312,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071944,GO:0080007,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.00000000000000000000000000000000000001951 148.0
HFD3_k127_690479_56 Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP K01004 - 2.7.8.24 0.00000000000000000000000000000000000003271 153.0
HFD3_k127_690479_57 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000001057 145.0
HFD3_k127_690479_58 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.000000000000000000000000000000000002874 147.0
HFD3_k127_690479_59 - - - - 0.00000000000000000000000000000000003353 156.0
HFD3_k127_690479_6 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 614.0
HFD3_k127_690479_60 DNA-binding transcription factor activity K18996 - - 0.00000000000000000000000000000001333 131.0
HFD3_k127_690479_61 Redoxin - - - 0.00000000000000000000000000000002032 141.0
HFD3_k127_690479_62 - - - - 0.0000000000000000000000000000001035 128.0
HFD3_k127_690479_63 Required for disulfide bond formation in some proteins K03611 - - 0.000000000000000000000000000002911 126.0
HFD3_k127_690479_65 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000001503 118.0
HFD3_k127_690479_66 endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000001017 112.0
HFD3_k127_690479_67 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.000000000000000000005085 96.0
HFD3_k127_690479_69 Ribosomal RNA small subunit methyltransferase G K03501 - 2.1.1.170 0.0000000000000000002611 94.0
HFD3_k127_690479_7 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005128 589.0
HFD3_k127_690479_71 FR47-like protein - - - 0.000000000000000006095 93.0
HFD3_k127_690479_73 Ribosomal protein L34 K02914 - - 0.0000000007428 69.0
HFD3_k127_690479_74 Endonuclease Exonuclease phosphatase - - - 0.000000000753 70.0
HFD3_k127_690479_75 lipolytic protein G-D-S-L family - - - 0.0000000008807 69.0
HFD3_k127_690479_76 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000001377 66.0
HFD3_k127_690479_77 AntiSigma factor - - - 0.0000002278 61.0
HFD3_k127_690479_78 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 GO:0008150,GO:0040007 3.1.26.5 0.0000007102 58.0
HFD3_k127_690479_8 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007349 572.0
HFD3_k127_690479_80 protoporphyrinogen oxidase activity - - - 0.0000127 51.0
HFD3_k127_690479_9 Cell cycle protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007652 593.0
HFD3_k127_6918622_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 6.799e-251 785.0
HFD3_k127_6918622_1 ABC transporter transmembrane region K06147 - - 8.408e-237 749.0
HFD3_k127_6918622_10 Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds K04073 - 1.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 407.0
HFD3_k127_6918622_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K00446 - 1.13.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 388.0
HFD3_k127_6918622_12 Sir2 family K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000663 355.0
HFD3_k127_6918622_13 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 354.0
HFD3_k127_6918622_14 Fumarylacetoacetate (FAA) hydrolase family K18364 - 4.2.1.132,4.2.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 310.0
HFD3_k127_6918622_15 Fumarylacetoacetate (FAA) hydrolase family K01617 - 4.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 287.0
HFD3_k127_6918622_16 myo-inosose-2 dehydratase activity K03335 - 4.2.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000219 260.0
HFD3_k127_6918622_17 Nitronate monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000004459 246.0
HFD3_k127_6918622_18 Histidine phosphatase superfamily (branch 1) - - - 0.00000000000000000000000000000000000000000000000000000000000002341 246.0
HFD3_k127_6918622_2 ThiF family - - - 3.039e-203 637.0
HFD3_k127_6918622_20 - - - - 0.0000000000000000000000000000000000000000000000000000000005812 208.0
HFD3_k127_6918622_21 - - - - 0.00000000000000000000000000000000000000000000000000002211 196.0
HFD3_k127_6918622_22 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000000000000002286 183.0
HFD3_k127_6918622_23 endonuclease activity - - - 0.0000000000000000000000000000000000008618 146.0
HFD3_k127_6918622_24 endoribonuclease L-PSP - - - 0.000000000000000000000000000000000009379 145.0
HFD3_k127_6918622_25 - - - - 0.0000000000000000000000000000000001034 148.0
HFD3_k127_6918622_26 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000008847 134.0
HFD3_k127_6918622_27 oxidoreductase activity, acting on diphenols and related substances as donors K02636 - 1.10.9.1 0.00000000000000000000004658 104.0
HFD3_k127_6918622_28 SnoaL-like domain - - - 0.0000000000000000000005656 102.0
HFD3_k127_6918622_29 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000001198 100.0
HFD3_k127_6918622_3 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K03520 - 1.2.5.3 2.562e-199 647.0
HFD3_k127_6918622_30 F420H(2)-dependent quinone reductase - - - 0.000000000000000000003485 97.0
HFD3_k127_6918622_31 Cytochrome c K00406,K03889,K17222,K19713 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005507,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006464,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016667,GO:0016669,GO:0016740,GO:0016782,GO:0016783,GO:0018192,GO:0018193,GO:0018198,GO:0018307,GO:0019417,GO:0019538,GO:0020037,GO:0022900,GO:0031224,GO:0031226,GO:0036211,GO:0040007,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0046982,GO:0046983,GO:0048037,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:0098822,GO:1901363,GO:1901564 1.8.2.2 0.00000000002364 71.0
HFD3_k127_6918622_32 Iron-containing redox enzyme K06137 - 1.3.3.11 0.0000003494 61.0
HFD3_k127_6918622_33 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.000002125 55.0
HFD3_k127_6918622_34 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00001266 56.0
HFD3_k127_6918622_4 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 575.0
HFD3_k127_6918622_5 DmpG-like communication domain K01666 - 4.1.3.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 508.0
HFD3_k127_6918622_6 Methionine synthase K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 507.0
HFD3_k127_6918622_7 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 505.0
HFD3_k127_6918622_8 ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 417.0
HFD3_k127_6918622_9 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000729 407.0
HFD3_k127_6993985_0 glycine cleavage T protein (aminomethyl transferase) K19191 - 1.5.3.19 0.0 1118.0
HFD3_k127_6993985_1 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 1.764e-279 881.0
HFD3_k127_6993985_10 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005497 444.0
HFD3_k127_6993985_11 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 409.0
HFD3_k127_6993985_12 belongs to the sigma-70 factor family K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 409.0
HFD3_k127_6993985_13 Daunorubicin resistance ABC transporter ATP-binding subunit K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 391.0
HFD3_k127_6993985_14 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 352.0
HFD3_k127_6993985_15 Peptidase inhibitor I9 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 361.0
HFD3_k127_6993985_16 belongs to the urease gamma subunit family K14048 - 3.5.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 323.0
HFD3_k127_6993985_17 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 319.0
HFD3_k127_6993985_18 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 319.0
HFD3_k127_6993985_19 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 304.0
HFD3_k127_6993985_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 4.543e-214 684.0
HFD3_k127_6993985_20 Peptidase family M48 K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 304.0
HFD3_k127_6993985_21 ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009556 292.0
HFD3_k127_6993985_22 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003585 291.0
HFD3_k127_6993985_23 Esterase K03928 - 3.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005147 274.0
HFD3_k127_6993985_24 N-acetyltransferase - GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008080,GO:0008150,GO:0008152,GO:0009056,GO:0009605,GO:0009607,GO:0009987,GO:0010941,GO:0016137,GO:0016139,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016999,GO:0017001,GO:0017144,GO:0030647,GO:0030649,GO:0031347,GO:0031349,GO:0032101,GO:0032103,GO:0034069,GO:0035821,GO:0040007,GO:0042802,GO:0043067,GO:0043207,GO:0044003,GO:0044068,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044248,GO:0044403,GO:0044419,GO:0044531,GO:0048518,GO:0048583,GO:0048584,GO:0050727,GO:0050729,GO:0050789,GO:0050794,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052032,GO:0052035,GO:0052040,GO:0052164,GO:0052167,GO:0052173,GO:0052200,GO:0052248,GO:0052255,GO:0052256,GO:0052259,GO:0052303,GO:0052306,GO:0052509,GO:0052510,GO:0052550,GO:0052552,GO:0052553,GO:0052564,GO:0052567,GO:0052572,GO:0065007,GO:0071704,GO:0075136,GO:0080134,GO:1901135,GO:1901136,GO:1901575,GO:1901657,GO:1901658 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006812 276.0
HFD3_k127_6993985_25 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000263 278.0
HFD3_k127_6993985_26 PFAM glycoside hydrolase family 39 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001469 268.0
HFD3_k127_6993985_27 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000009101 243.0
HFD3_k127_6993985_28 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00015,K00058,K16843 - 1.1.1.26,1.1.1.310,1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000005875 218.0
HFD3_k127_6993985_29 4fe-4S ferredoxin, iron-sulfur binding domain protein K03616 - - 0.0000000000000000000000000000000000000000000000000007318 185.0
HFD3_k127_6993985_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.43e-212 669.0
HFD3_k127_6993985_30 Aminoacyl-tRNA editing domain K03976 - - 0.00000000000000000000000000000000000000000000000001129 185.0
HFD3_k127_6993985_31 DinB superfamily - - - 0.000000000000000000000000000000000000000000000005693 181.0
HFD3_k127_6993985_32 PFAM Carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.00000000000000000000000000000000000000000002133 176.0
HFD3_k127_6993985_33 YjbR - - - 0.0000000000000000000000000000000000000000001052 162.0
HFD3_k127_6993985_34 Cyclic nucleotide-binding domain - - - 0.00000000000000000000000000000000000000001195 177.0
HFD3_k127_6993985_35 YCII-related domain - - - 0.00000000000000000000000000000000005523 145.0
HFD3_k127_6993985_36 regulatory protein, arsR - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000164 130.0
HFD3_k127_6993985_37 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000001668 134.0
HFD3_k127_6993985_38 Universal stress protein - - - 0.00000000000000000000000000002926 121.0
HFD3_k127_6993985_39 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.0000000000000000000000000002112 132.0
HFD3_k127_6993985_4 Peptidase dimerisation domain - - - 6.129e-196 627.0
HFD3_k127_6993985_40 PFAM Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000002708 120.0
HFD3_k127_6993985_41 GYD domain - - - 0.00000000000000000000002706 109.0
HFD3_k127_6993985_42 FR47-like protein - - - 0.00000000000000005912 95.0
HFD3_k127_6993985_43 ABC-2 family transporter protein K01992 - - 0.00000000000003577 83.0
HFD3_k127_6993985_44 Protein conserved in bacteria - - - 0.000000003675 61.0
HFD3_k127_6993985_45 Negative regulator of - - - 0.000001863 58.0
HFD3_k127_6993985_5 sulphate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009935 556.0
HFD3_k127_6993985_6 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007467 471.0
HFD3_k127_6993985_7 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 467.0
HFD3_k127_6993985_8 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004355 452.0
HFD3_k127_6993985_9 Zn-dependent oxidoreductase, NADPH quinone reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008902 421.0
HFD3_k127_7039009_0 PFAM carboxyl transferase - - - 4.543e-253 795.0
HFD3_k127_7039009_1 Class-II DAHP synthetase family K01626 - 2.5.1.54 6.08e-229 721.0
HFD3_k127_7039009_10 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008097 465.0
HFD3_k127_7039009_11 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K20940 - 1.14.13.218 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 467.0
HFD3_k127_7039009_12 DNA primase, small subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 448.0
HFD3_k127_7039009_13 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 417.0
HFD3_k127_7039009_14 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 407.0
HFD3_k127_7039009_15 Catalyzes the formation of methionine from L-homocysteine and S-adenosyl-L-methionine K00544,K00548 - 2.1.1.13,2.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 392.0
HFD3_k127_7039009_16 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 383.0
HFD3_k127_7039009_17 Peptidase M1, membrane alanine aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 378.0
HFD3_k127_7039009_18 PFAM Metallo-beta-lactamase superfamily - GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006090,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019184,GO:0019752,GO:0031974,GO:0032787,GO:0034641,GO:0042398,GO:0043043,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0051186,GO:0051188,GO:0070013,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 334.0
HFD3_k127_7039009_19 2OG-Fe(II) oxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008632 324.0
HFD3_k127_7039009_2 ABC transporter transmembrane region K06147 - - 1.674e-208 681.0
HFD3_k127_7039009_20 PFAM Peptidase family S58 K18572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 323.0
HFD3_k127_7039009_21 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 316.0
HFD3_k127_7039009_22 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 305.0
HFD3_k127_7039009_23 Acetyltransferase (isoleucine patch K00661 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 2.3.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 300.0
HFD3_k127_7039009_24 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 298.0
HFD3_k127_7039009_25 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 295.0
HFD3_k127_7039009_26 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 300.0
HFD3_k127_7039009_27 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 304.0
HFD3_k127_7039009_28 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004554 296.0
HFD3_k127_7039009_29 alpha-ribazole phosphatase activity K02226,K15634 - 3.1.3.73,5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 288.0
HFD3_k127_7039009_3 Flavoprotein involved in K transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 625.0
HFD3_k127_7039009_30 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008287 270.0
HFD3_k127_7039009_31 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002109 278.0
HFD3_k127_7039009_32 Biopterin-dependent aromatic amino acid hydroxylase K00500 - 1.14.16.1 0.000000000000000000000000000000000000000000000000000000000000000000000000007186 260.0
HFD3_k127_7039009_33 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001253 254.0
HFD3_k127_7039009_34 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000000000000000000001696 241.0
HFD3_k127_7039009_35 Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP K01004 GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050520,GO:0071704,GO:0090407,GO:1901576 2.7.8.24 0.000000000000000000000000000000000000000000000007155 181.0
HFD3_k127_7039009_36 carboxylic acid catabolic process K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000001025 171.0
HFD3_k127_7039009_37 5-methyl-5,6,7,8-tetrahydromethanopterin-dependent methyltransferase activity - - - 0.000000000000000000000000000000000000000001577 165.0
HFD3_k127_7039009_39 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000005318 154.0
HFD3_k127_7039009_4 alcohol dehydrogenase K00153 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.306 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 608.0
HFD3_k127_7039009_40 response to heat K07090 - - 0.0000000000000000000000000000000003906 141.0
HFD3_k127_7039009_42 helix_turn_helix ASNC type - - - 0.00000000000000000000000000000008615 130.0
HFD3_k127_7039009_43 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000212 141.0
HFD3_k127_7039009_44 Transcriptional regulator - - - 0.0000000000000000000000003258 108.0
HFD3_k127_7039009_45 YhhN family - - - 0.000000000000000000000001935 111.0
HFD3_k127_7039009_46 CoA-binding domain protein - - - 0.000000000000000002817 94.0
HFD3_k127_7039009_49 glyoxalase III activity - - - 0.000000000000002996 82.0
HFD3_k127_7039009_5 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009228 576.0
HFD3_k127_7039009_50 - - - - 0.00000000009759 68.0
HFD3_k127_7039009_51 - - - - 0.0003273 52.0
HFD3_k127_7039009_53 - - - - 0.0008417 51.0
HFD3_k127_7039009_6 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 552.0
HFD3_k127_7039009_7 ABC transporter transmembrane region K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004838 561.0
HFD3_k127_7039009_8 DegT/DnrJ/EryC1/StrS aminotransferase family K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 523.0
HFD3_k127_7039009_9 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 507.0
HFD3_k127_7050422_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 1.237e-264 839.0
HFD3_k127_7050422_1 4-hydroxyphenylacetate 3-hydroxylase N terminal K00483,K21726 - 1.14.13.166,1.14.13.29,1.14.14.9 2.629e-243 764.0
HFD3_k127_7050422_10 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.000000000000000000000000000000000000000000000000000000000000002081 237.0
HFD3_k127_7050422_11 CO dehydrogenase flavoprotein domain protein K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000008499 225.0
HFD3_k127_7050422_12 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000002361 193.0
HFD3_k127_7050422_13 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000001879 193.0
HFD3_k127_7050422_14 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000001698 183.0
HFD3_k127_7050422_15 Protein of unknown function (DUF2848) - - - 0.0000000000000000000000000000000000000037 164.0
HFD3_k127_7050422_16 FCD - - - 0.0000000000000000000000000000000000003144 149.0
HFD3_k127_7050422_17 PRC-barrel domain - - - 0.000000000000000000000000000000000001047 149.0
HFD3_k127_7050422_18 ChrR Cupin-like domain - - - 0.000000000000000000000000000000001145 140.0
HFD3_k127_7050422_19 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03406,K21009 - - 0.00000000000000000000000000000000199 149.0
HFD3_k127_7050422_2 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005355 561.0
HFD3_k127_7050422_20 transcriptional regulator - - - 0.0000000000000000000000000005052 117.0
HFD3_k127_7050422_21 PRC-barrel domain - - - 0.00000000000000000000000008702 114.0
HFD3_k127_7050422_22 Domain of unknown function (DUF1989) - - - 0.000000000000000000000001674 111.0
HFD3_k127_7050422_23 Protein of unknown function (DUF3995) - - - 0.00000000000000005882 89.0
HFD3_k127_7050422_24 Flavin reductase like domain K09024 - - 0.00000000000001995 81.0
HFD3_k127_7050422_25 PhoQ Sensor - - - 0.000000000001978 81.0
HFD3_k127_7050422_26 - - - - 0.0000006092 57.0
HFD3_k127_7050422_27 PFAM transposase IS3 IS911 family protein K07483 - - 0.00004249 47.0
HFD3_k127_7050422_3 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 527.0
HFD3_k127_7050422_4 Peptidase S8 and S53 subtilisin kexin sedolisin K17734 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 406.0
HFD3_k127_7050422_5 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008346 388.0
HFD3_k127_7050422_6 involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007626 384.0
HFD3_k127_7050422_7 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 321.0
HFD3_k127_7050422_8 TAP-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001585 269.0
HFD3_k127_7050422_9 ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003431 253.0
HFD3_k127_7063214_0 DEAD-like helicases superfamily K03724,K06877 - - 0.0 1799.0
HFD3_k127_7063214_1 Belongs to the GcvT family K00315 - 1.5.8.4 0.0 1054.0
HFD3_k127_7063214_10 Glycosyl transferase 4-like domain - - - 9.247e-216 676.0
HFD3_k127_7063214_11 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 2.541e-214 677.0
HFD3_k127_7063214_12 Aldehyde dehydrogenase family K00128 - 1.2.1.3 1.397e-205 651.0
HFD3_k127_7063214_13 Trimethylamine methyltransferase (MTTB) - - - 2.695e-201 639.0
HFD3_k127_7063214_14 Cell division protein FtsA K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 609.0
HFD3_k127_7063214_15 Metallopeptidase family M24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 588.0
HFD3_k127_7063214_16 RNB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 518.0
HFD3_k127_7063214_17 mandelate racemase muconate lactonizing K01856 - 5.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007857 505.0
HFD3_k127_7063214_18 PFAM Glycoside hydrolase 15-related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 501.0
HFD3_k127_7063214_19 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 496.0
HFD3_k127_7063214_2 AAA domain - - - 5.533e-301 938.0
HFD3_k127_7063214_20 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007841 471.0
HFD3_k127_7063214_21 ROK family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 469.0
HFD3_k127_7063214_22 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003949 456.0
HFD3_k127_7063214_23 Pfam:Zinicin_2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 453.0
HFD3_k127_7063214_24 CO dehydrogenase/acetyl-CoA synthase delta subunit K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005065 449.0
HFD3_k127_7063214_25 Thioesterase-like superfamily K10805 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 426.0
HFD3_k127_7063214_26 dipeptide transport K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004281 433.0
HFD3_k127_7063214_27 Flavin containing amine oxidoreductase K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004635 432.0
HFD3_k127_7063214_28 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 387.0
HFD3_k127_7063214_29 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 375.0
HFD3_k127_7063214_3 5'-nucleotidase, C-terminal domain K01119 - 3.1.3.6,3.1.4.16 1.268e-296 922.0
HFD3_k127_7063214_30 ATPases associated with a variety of cellular activities K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 366.0
HFD3_k127_7063214_31 Transcriptional regulatory protein, C terminal K07776 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 340.0
HFD3_k127_7063214_32 iron dependent repressor K03709 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006355,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009058,GO:0009237,GO:0009712,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016151,GO:0018958,GO:0019184,GO:0019219,GO:0019222,GO:0019290,GO:0019540,GO:0019748,GO:0030145,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0044550,GO:0045892,GO:0045934,GO:0046870,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0050897,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 333.0
HFD3_k127_7063214_33 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 335.0
HFD3_k127_7063214_34 Epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007234 327.0
HFD3_k127_7063214_35 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006502 332.0
HFD3_k127_7063214_36 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006871 329.0
HFD3_k127_7063214_37 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008271 311.0
HFD3_k127_7063214_38 His Kinase A (phosphoacceptor) domain K07768 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 306.0
HFD3_k127_7063214_39 PhoU domain K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006492 304.0
HFD3_k127_7063214_4 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 4.4e-293 915.0
HFD3_k127_7063214_40 PFAM Iron-containing alcohol dehydrogenase K19714 GO:0003674,GO:0003824,GO:0004022,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.1.3.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001341 298.0
HFD3_k127_7063214_41 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007133 304.0
HFD3_k127_7063214_42 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007761 266.0
HFD3_k127_7063214_43 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000001141 278.0
HFD3_k127_7063214_44 Belongs to the GcvT family K00302 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000005612 269.0
HFD3_k127_7063214_45 Fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001044 241.0
HFD3_k127_7063214_46 MoaE protein K03635 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000000000000001108 239.0
HFD3_k127_7063214_47 Aldose 1-epimerase K01785 - 5.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000004226 231.0
HFD3_k127_7063214_48 Belongs to the peptidase S8 family K01173 - - 0.000000000000000000000000000000000000000000000000000000000000006724 239.0
HFD3_k127_7063214_49 Major facilitator Superfamily - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000001204 227.0
HFD3_k127_7063214_5 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 2.476e-280 881.0
HFD3_k127_7063214_50 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000002486 208.0
HFD3_k127_7063214_51 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000000000006733 188.0
HFD3_k127_7063214_52 Protein of unknown function (DUF1638) - - - 0.000000000000000000000000000000000000000000000000003399 188.0
HFD3_k127_7063214_53 Predicted membrane protein (DUF2207) - - - 0.000000000000000000000000000000000000000000002777 185.0
HFD3_k127_7063214_54 Sortase family K07284 - 3.4.22.70 0.00000000000000000000000000000000000000000008304 179.0
HFD3_k127_7063214_55 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.0000000000000000000000000000000000003242 143.0
HFD3_k127_7063214_56 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.000000000000000000000000000000000001753 139.0
HFD3_k127_7063214_57 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000005227 119.0
HFD3_k127_7063214_58 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00000000000000000000000007456 111.0
HFD3_k127_7063214_59 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000001253 122.0
HFD3_k127_7063214_6 ABC transporter ATPase permease K06147 - - 6.683e-256 801.0
HFD3_k127_7063214_60 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.0000000000000000000000004963 118.0
HFD3_k127_7063214_61 - - - - 0.00000000000000000000004279 103.0
HFD3_k127_7063214_62 PFAM peptidase M10A and M12B, matrixin and adamalysin - - - 0.0000000000000000001149 104.0
HFD3_k127_7063214_63 transcriptional regulator - - - 0.0000000000000000001375 96.0
HFD3_k127_7063214_65 Virulence factor - - - 0.0000000003748 71.0
HFD3_k127_7063214_66 PFAM Sarcosine oxidase delta subunit heterotetrameric K00304 - 1.5.3.1 0.0000000006282 72.0
HFD3_k127_7063214_67 - - - - 0.000000001499 64.0
HFD3_k127_7063214_68 protein secretion K03116 - - 0.00000001956 58.0
HFD3_k127_7063214_7 Domain of unknown function (DUF4445) - - - 2.231e-232 736.0
HFD3_k127_7063214_8 COG1132 ABC-type multidrug transport system, ATPase and permease components K06147 - - 5.148e-227 720.0
HFD3_k127_7063214_9 Trimethylamine methyltransferase (MTTB) - - - 7.055e-216 709.0
HFD3_k127_7116240_0 NADH:flavin oxidoreductase / NADH oxidase family K00219,K21833 - 1.3.1.34 1.431e-275 865.0
HFD3_k127_7116240_1 5'-nucleotidase, C-terminal domain K01119 - 3.1.3.6,3.1.4.16 5.7e-269 851.0
HFD3_k127_7116240_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000004371 226.0
HFD3_k127_7116240_3 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000000000006681 226.0
HFD3_k127_7116240_4 Amidohydrolase family - - - 0.000000000000004424 90.0
HFD3_k127_7116240_5 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.0001028 45.0
HFD3_k127_7142063_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 554.0
HFD3_k127_7142063_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 428.0
HFD3_k127_7142063_2 FAD binding domain K21401 - 1.3.99.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006 351.0
HFD3_k127_7142063_3 redox protein regulator of disulfide bond formation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005618 279.0
HFD3_k127_7142063_4 Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000001048 210.0
HFD3_k127_7142063_5 Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000003709 197.0
HFD3_k127_7142063_6 A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics - - - 0.00000000000000000000000000000000000000000000000007027 186.0
HFD3_k127_7142063_7 transcriptional regulator - - - 0.000000000000000000000000000000000000007365 154.0
HFD3_k127_7142063_8 AzlC protein - - - 0.000000000000000000000000003404 121.0
HFD3_k127_7157767_0 ABC1 family - - - 2.188e-239 753.0
HFD3_k127_7157767_1 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 444.0
HFD3_k127_7157767_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 402.0
HFD3_k127_7157767_3 inositol monophosphatase K01082 - 3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 321.0
HFD3_k127_7157767_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 318.0
HFD3_k127_7157767_5 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures K07503 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 307.0
HFD3_k127_7157767_6 ABC transporter - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000002782 217.0
HFD3_k127_7157767_7 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000003355 205.0
HFD3_k127_7174698_0 Sodium Bile acid symporter family K03325,K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005251 526.0
HFD3_k127_7174698_1 Methyltransferase type 11 K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 303.0
HFD3_k127_7174698_10 DNA-binding transcription factor activity - - - 0.000000000000000000000007878 117.0
HFD3_k127_7174698_11 Protein of unknown function (DUF433) - - - 0.00000000009468 68.0
HFD3_k127_7174698_12 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000005346 59.0
HFD3_k127_7174698_2 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000000004235 203.0
HFD3_k127_7174698_3 Pfam Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000006682 209.0
HFD3_k127_7174698_4 Sigma 54 modulation/S30EA ribosomal protein C terminus - - - 0.00000000000000000000000000000000000000000000002015 188.0
HFD3_k127_7174698_5 Domain of unknown function (DUF2703) - - - 0.0000000000000000000000000000000000000000002212 164.0
HFD3_k127_7174698_6 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000001281 135.0
HFD3_k127_7174698_7 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046983,GO:0070037,GO:0070038,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.177 0.000000000000000000000000000004812 121.0
HFD3_k127_7174698_8 Belongs to the small heat shock protein (HSP20) family K13993 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016310,GO:0019538,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0036294,GO:0040007,GO:0040008,GO:0042221,GO:0042594,GO:0043170,GO:0043207,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045926,GO:0046777,GO:0048519,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071496,GO:0071704,GO:0071944,GO:0075136,GO:1901564 - 0.00000000000000000000000001474 113.0
HFD3_k127_7174698_9 peroxiredoxin activity K01607 - 4.1.1.44 0.0000000000000000000000004747 108.0
HFD3_k127_7175138_0 collagen metabolic process - - - 4.737e-219 711.0
HFD3_k127_7175138_1 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004424 392.0
HFD3_k127_7175138_10 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000009731 146.0
HFD3_k127_7175138_11 TfoX N-terminal domain - - - 0.000000000000000000000000000000000006578 140.0
HFD3_k127_7175138_12 Phosphotransferase enzyme family K18844,K18845 - 2.1.1.179 0.0000000000002412 77.0
HFD3_k127_7175138_13 antisigma factor binding K04749,K17763,K20978 - - 0.000000009583 61.0
HFD3_k127_7175138_14 Phosphotransferase enzyme family K18844,K18845 - 2.1.1.179 0.00002216 53.0
HFD3_k127_7175138_15 STAS domain - - - 0.00002224 55.0
HFD3_k127_7175138_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007361 358.0
HFD3_k127_7175138_3 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 334.0
HFD3_k127_7175138_4 Anion-transporting ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001305 260.0
HFD3_k127_7175138_5 Dihydrofolate reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001503 258.0
HFD3_k127_7175138_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000492 223.0
HFD3_k127_7175138_7 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000206 228.0
HFD3_k127_7175138_8 ANTAR - - - 0.00000000000000000000000000000000000000000000000000000000000008426 225.0
HFD3_k127_7175138_9 ANTAR - - - 0.000000000000000000000000000000000000000006751 163.0
HFD3_k127_7310620_0 belongs to the sigma-70 factor family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 558.0
HFD3_k127_7310620_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 483.0
HFD3_k127_7310620_10 Copper resistance protein D - - - 0.0000000000000000000000000000000000000001629 154.0
HFD3_k127_7310620_11 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000001046 139.0
HFD3_k127_7310620_12 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.00000000000000000000000000000000003526 158.0
HFD3_k127_7310620_13 Belongs to the TPP enzyme family K01637,K01652 - 2.2.1.6,4.1.3.1 0.0000000000000000001537 106.0
HFD3_k127_7310620_14 hemerythrin HHE cation binding domain - - - 0.00000000000000005763 87.0
HFD3_k127_7310620_15 PFAM Protein kinase domain K02486 - 2.7.13.3 0.0000004142 59.0
HFD3_k127_7310620_16 COGs COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.000001247 56.0
HFD3_k127_7310620_17 Fungalysin metallopeptidase (M36) - - - 0.000002046 63.0
HFD3_k127_7310620_2 Cupredoxin-like domain K00368 - 1.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 415.0
HFD3_k127_7310620_3 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004262 377.0
HFD3_k127_7310620_4 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007342 276.0
HFD3_k127_7310620_5 YCII-related domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007289 268.0
HFD3_k127_7310620_7 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001247 251.0
HFD3_k127_7310620_8 COG2346, Truncated hemoglobins K06886 - - 0.0000000000000000000000000000000000000000000000000000001646 203.0
HFD3_k127_7310620_9 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000008213 189.0
HFD3_k127_7320898_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1237.0
HFD3_k127_7320898_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 8.023e-207 671.0
HFD3_k127_7320898_2 MazG nucleotide pyrophosphohydrolase domain K02499 - - 6.668e-202 640.0
HFD3_k127_7320898_3 cell cycle K05589,K13052 - - 0.0000000000000000000000007363 110.0
HFD3_k127_7398340_0 C-terminal, D2-small domain, of ClpB protein K03696 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944 - 0.0 1147.0
HFD3_k127_7398340_1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 1.016e-306 959.0
HFD3_k127_7398340_10 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 484.0
HFD3_k127_7398340_11 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004985 451.0
HFD3_k127_7398340_12 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 446.0
HFD3_k127_7398340_13 Polyprenyl synthetase K00805 - 2.5.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 425.0
HFD3_k127_7398340_14 Cytochrome b(C-terminal)/b6/petD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 377.0
HFD3_k127_7398340_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007682 366.0
HFD3_k127_7398340_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 332.0
HFD3_k127_7398340_17 oxidoreductase activity, acting on diphenols and related substances as donors K02636,K03886 - 1.10.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 302.0
HFD3_k127_7398340_18 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 288.0
HFD3_k127_7398340_19 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003311 266.0
HFD3_k127_7398340_2 protein synonym multiple resistance and pH homeostasis protein A K00341 - 1.6.5.3 3.954e-254 797.0
HFD3_k127_7398340_20 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009244 254.0
HFD3_k127_7398340_21 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001854 243.0
HFD3_k127_7398340_22 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000003641 215.0
HFD3_k127_7398340_23 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000369 214.0
HFD3_k127_7398340_24 - - - - 0.00000000000000000000000000000000000000000000000000000002016 210.0
HFD3_k127_7398340_25 Choline/ethanolamine kinase - - - 0.00000000000000000000000000000000000000000000000004505 190.0
HFD3_k127_7398340_26 peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000004007 181.0
HFD3_k127_7398340_27 Peptidase C26 - - - 0.0000000000000000000000000000000000000000000001477 176.0
HFD3_k127_7398340_28 peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000000002039 179.0
HFD3_k127_7398340_29 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000006937 179.0
HFD3_k127_7398340_3 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 9.599e-246 773.0
HFD3_k127_7398340_30 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000000000000000003339 157.0
HFD3_k127_7398340_31 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000000372 136.0
HFD3_k127_7398340_32 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.00000000000000000000000000002761 117.0
HFD3_k127_7398340_33 Psort location Cytoplasmic, score - - - 0.00000000003448 74.0
HFD3_k127_7398340_34 HYR domain - - - 0.000000001767 70.0
HFD3_k127_7398340_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 3.206e-238 750.0
HFD3_k127_7398340_5 Protein synonym NADH dehydrogenase I subunit M K00342 - 1.6.5.3 4.228e-237 745.0
HFD3_k127_7398340_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 583.0
HFD3_k127_7398340_7 FAD binding domain K21401 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016491,GO:0016627,GO:0030312,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 1.3.99.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 553.0
HFD3_k127_7398340_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006522 516.0
HFD3_k127_7398340_9 Cytochrome b/b6/petB K03891 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 475.0
HFD3_k127_7412971_0 ABC transporter transmembrane region K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 346.0
HFD3_k127_7412971_1 PFAM pfkB family carbohydrate kinase K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 334.0
HFD3_k127_7412971_11 Phosphotransferase enzyme family - - - 0.0000000000005984 79.0
HFD3_k127_7412971_2 Phosphoenolpyruvate phosphomutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 301.0
HFD3_k127_7412971_3 GDP-mannose mannosyl hydrolase activity K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000002667 189.0
HFD3_k127_7412971_4 nUDIX hydrolase - - - 0.00000000000000000000000000000000000000005267 161.0
HFD3_k127_7412971_5 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.0000000000000000000000000000000000001336 147.0
HFD3_k127_7412971_7 arsenate reductase (glutaredoxin) activity K00537 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.20.4.1 0.000000000000000000000000000000001241 132.0
HFD3_k127_7412971_8 Transglycosylase associated protein - - - 0.00000000000000000000000000004356 118.0
HFD3_k127_7412971_9 Protein of unknown function (DUF4031) - - - 0.0000000000000000000000000006633 116.0
HFD3_k127_7447772_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 5e-324 1001.0
HFD3_k127_7447772_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 491.0
HFD3_k127_7447772_2 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02298 - 1.10.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009397 451.0
HFD3_k127_7447772_3 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) K02862 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 346.0
HFD3_k127_7447772_4 Cytochrome c oxidase subunit III K02276,K02299 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000833 301.0
HFD3_k127_7447772_5 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000008475 241.0
HFD3_k127_7447772_6 - - - - 0.00000000000000000000000000000000000000000000000000000003904 211.0
HFD3_k127_7447772_7 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000006119 194.0
HFD3_k127_7447772_8 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.00000000000000000000000002162 111.0
HFD3_k127_7474540_0 helicase activity - - - 4.664e-321 1000.0
HFD3_k127_7474540_1 Belongs to the cysteine synthase cystathionine beta- synthase family - - - 1.17e-259 807.0
HFD3_k127_7474540_10 Conserved hypothetical protein (DUF2461) - - - 0.00000000000000000000000000000000000000000000000000000000000000000429 232.0
HFD3_k127_7474540_11 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000004415 177.0
HFD3_k127_7474540_12 PFAM Helix-turn-helix, type 11 domain protein - - - 0.00000000000000000000000000000000000000000006437 183.0
HFD3_k127_7474540_13 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000004084 101.0
HFD3_k127_7474540_14 - - - - 0.0000000001904 65.0
HFD3_k127_7474540_2 PFAM magnesium chelatase ChlI subunit K07391 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 579.0
HFD3_k127_7474540_3 Pyridoxal-phosphate dependent enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 398.0
HFD3_k127_7474540_4 Putative serine dehydratase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004605 389.0
HFD3_k127_7474540_5 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000485 372.0
HFD3_k127_7474540_6 DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007389 343.0
HFD3_k127_7474540_7 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 319.0
HFD3_k127_7474540_8 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000004303 249.0
HFD3_k127_7474540_9 Phage integrase, N-terminal SAM-like domain K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000002957 240.0
HFD3_k127_748132_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 5.917e-270 852.0
HFD3_k127_748132_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 7.366e-259 809.0
HFD3_k127_748132_10 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005765 402.0
HFD3_k127_748132_11 beta-1,4-mannooligosaccharide phosphorylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007543 393.0
HFD3_k127_748132_12 ABC-type dipeptide oligopeptide nickel transport K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 381.0
HFD3_k127_748132_13 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 373.0
HFD3_k127_748132_14 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 352.0
HFD3_k127_748132_15 Belongs to the ABC transporter superfamily K02031,K15583 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 346.0
HFD3_k127_748132_16 FGGY family of carbohydrate kinase, N-terminal domain protein K00854 - 2.7.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 341.0
HFD3_k127_748132_17 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 318.0
HFD3_k127_748132_18 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000121 258.0
HFD3_k127_748132_19 Cation efflux family - - - 0.000000000000000000000000000000000000000000000000000000000000000001228 233.0
HFD3_k127_748132_2 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 2.376e-196 619.0
HFD3_k127_748132_20 Pfam Isochorismatase K08281 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006769,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0071704,GO:0072524,GO:1901360,GO:1901564 3.5.1.19 0.00000000000000000000000000000000000000000000000000000009005 208.0
HFD3_k127_748132_21 Family of unknown function (DUF1028) - - - 0.000000000000000000000000000000000000000000000000000003435 216.0
HFD3_k127_748132_22 YjbR - - - 0.00000000000000000000000000000000000000000000000000001773 190.0
HFD3_k127_748132_23 Polysaccharide deacetylase K01448,K22278 - 3.5.1.104,3.5.1.28 0.00000000000000000000000000000000000000000000000000003724 208.0
HFD3_k127_748132_24 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000003641 179.0
HFD3_k127_748132_25 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000001564 175.0
HFD3_k127_748132_26 Belongs to the thioredoxin family K00384,K03671 - 1.8.1.9 0.00000000000000000000000000000000000000000003134 167.0
HFD3_k127_748132_27 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000002305 163.0
HFD3_k127_748132_28 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000009077 164.0
HFD3_k127_748132_29 transport, permease protein K01992 - - 0.00000000000000000000000000000000000171 150.0
HFD3_k127_748132_3 tRNA-splicing ligase RtcB K14415 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 611.0
HFD3_k127_748132_30 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000001289 123.0
HFD3_k127_748132_31 PFAM Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000002992 113.0
HFD3_k127_748132_32 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000004758 102.0
HFD3_k127_748132_33 Universal stress protein family - - - 0.000000000000006346 88.0
HFD3_k127_748132_34 2TM domain - - - 0.00000000000007929 75.0
HFD3_k127_748132_35 Nitroreductase family - - - 0.00000000008938 66.0
HFD3_k127_748132_36 COG1960 Acyl-CoA dehydrogenases - - - 0.000149 53.0
HFD3_k127_748132_37 transferase activity, transferring glycosyl groups - - - 0.0003507 45.0
HFD3_k127_748132_4 Pyridoxal-dependent decarboxylase conserved domain K01634,K18933 - 4.1.1.11,4.1.1.25,4.1.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 604.0
HFD3_k127_748132_5 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 551.0
HFD3_k127_748132_6 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483 - 1.14.14.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 525.0
HFD3_k127_748132_7 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 504.0
HFD3_k127_748132_8 Capsule synthesis protein K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 435.0
HFD3_k127_748132_9 AAA domain K07028 GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009987,GO:0030312,GO:0044464,GO:0044764,GO:0046812,GO:0051704,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 409.0
HFD3_k127_7557492_0 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005003 593.0
HFD3_k127_7557492_1 EamA-like transporter family - - - 0.0000000000000000000008361 106.0
HFD3_k127_7557492_2 - - - - 0.000000000000000000001827 96.0
HFD3_k127_7600152_0 Squalene--hopene cyclase K06045 - 4.2.1.129,5.4.99.17 3.666e-262 837.0
HFD3_k127_7600152_1 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 568.0
HFD3_k127_7600152_10 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000002765 149.0
HFD3_k127_7600152_11 carbamoyl transferase, NodU family K00612 - - 0.000000000000000000000000000000009957 130.0
HFD3_k127_7600152_12 regulatory protein TetR - - - 0.000000006159 67.0
HFD3_k127_7600152_13 Carbamoyltransferase C-terminus K00612 - - 0.00000007341 54.0
HFD3_k127_7600152_14 MT0933-like antitoxin protein - - - 0.000001234 53.0
HFD3_k127_7600152_15 transcriptional regulator - - - 0.00007329 54.0
HFD3_k127_7600152_16 Amino-transferase class IV - - - 0.0001393 44.0
HFD3_k127_7600152_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000664 496.0
HFD3_k127_7600152_3 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000748 447.0
HFD3_k127_7600152_4 squalene-associated FAD-dependent desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 451.0
HFD3_k127_7600152_5 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 299.0
HFD3_k127_7600152_6 Threonyl alanyl tRNA synthetase SAD K07050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 286.0
HFD3_k127_7600152_7 Squalene/phytoene synthase K02291 GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0016767,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004771 283.0
HFD3_k127_7600152_8 Squalene/phytoene synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000345 251.0
HFD3_k127_7600152_9 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000000000004997 201.0
HFD3_k127_7607396_0 Methylmalonyl-CoA mutase K14447 - 5.4.99.63 2.199e-313 971.0
HFD3_k127_7607396_1 ABC transporter transmembrane region K06147 - - 3.419e-266 834.0
HFD3_k127_7607396_10 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004752 342.0
HFD3_k127_7607396_11 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000901 260.0
HFD3_k127_7607396_12 Tyrosine phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008027 260.0
HFD3_k127_7607396_13 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001851 252.0
HFD3_k127_7607396_14 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000007722 214.0
HFD3_k127_7607396_15 PFAM class II aldolase adducin family protein - - - 0.0000000000000000000000000000000000000000000000000000000005781 209.0
HFD3_k127_7607396_16 Phage-related minor tail protein K15771,K18642,K20444 - - 0.000000000000000000000000000000000000000000000000000000008502 216.0
HFD3_k127_7607396_17 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000001965 190.0
HFD3_k127_7607396_18 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000001339 184.0
HFD3_k127_7607396_19 of HD superfamily K07023 - - 0.00000000000000000000000000000000000000000000000371 188.0
HFD3_k127_7607396_2 Type II secretion system (T2SS), protein E, N-terminal domain K02652 - - 4.432e-250 784.0
HFD3_k127_7607396_20 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000005017 169.0
HFD3_k127_7607396_21 - - - - 0.00000000000000000000000000000000000000004675 156.0
HFD3_k127_7607396_22 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000722 171.0
HFD3_k127_7607396_23 Metal-dependent hydrolase K07043 - - 0.000000000000000000000000000000000000005895 151.0
HFD3_k127_7607396_24 Belongs to the peptidase S51 family K13282 - 3.4.15.6 0.00000000000000000000000000000009587 139.0
HFD3_k127_7607396_25 DNA-binding protein - - - 0.000000000000000000000000000002238 131.0
HFD3_k127_7607396_27 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000002503 115.0
HFD3_k127_7607396_28 Belongs to the acetyltransferase family. ArgA subfamily - - - 0.000000000000000000000003697 113.0
HFD3_k127_7607396_29 pyridoxamine 5-phosphate K07005 - - 0.00000000000000000000005518 103.0
HFD3_k127_7607396_3 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 436.0
HFD3_k127_7607396_30 Mo-molybdopterin cofactor metabolic process K03636,K21142 - 2.8.1.12 0.00000000000000000002389 92.0
HFD3_k127_7607396_31 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000003653 74.0
HFD3_k127_7607396_32 hydrolase activity, acting on ester bonds K01259 - 3.4.11.5 0.000000000001104 74.0
HFD3_k127_7607396_33 protein secretion K03116 - - 0.00000001733 60.0
HFD3_k127_7607396_34 Exonuclease VII small subunit K03602 - 3.1.11.6 0.000004332 56.0
HFD3_k127_7607396_35 LysM domain - - - 0.000008939 58.0
HFD3_k127_7607396_36 PFAM Glycosyl transferase, group 1 K15521 - 2.4.1.250 0.0008703 43.0
HFD3_k127_7607396_4 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 444.0
HFD3_k127_7607396_5 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 427.0
HFD3_k127_7607396_6 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 441.0
HFD3_k127_7607396_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 394.0
HFD3_k127_7607396_8 5'-3' exonuclease, C-terminal SAM fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 387.0
HFD3_k127_7607396_9 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 353.0
HFD3_k127_7648877_0 MOSC N-terminal beta barrel domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 550.0
HFD3_k127_7648877_1 Transposase K07493 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008251 291.0
HFD3_k127_7648877_10 transcriptional regulator - - - 0.000000651 63.0
HFD3_k127_7648877_3 Transposase IS116/IS110/IS902 family - - - 0.000000000000000000000000000000000000000000001901 178.0
HFD3_k127_7648877_4 AAA ATPase domain - - - 0.000000000000000000000000000000000008094 158.0
HFD3_k127_7648877_5 KR domain K00059 - 1.1.1.100 0.000000000000000000000001317 113.0
HFD3_k127_7648877_6 Transposase K07493 - - 0.000000000000000000000003942 102.0
HFD3_k127_7648877_7 Transposase, Mutator family K07493 - - 0.000000000001252 69.0
HFD3_k127_7648877_8 - - - - 0.000000000007308 68.0
HFD3_k127_7648877_9 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000001811 66.0
HFD3_k127_7706021_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0 1771.0
HFD3_k127_7706021_1 Alpha-amylase domain K01187 - 3.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 594.0
HFD3_k127_7706021_10 CobW/HypB/UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 378.0
HFD3_k127_7706021_11 Non-essential cell division protein that could be required for efficient cell constriction - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004159 361.0
HFD3_k127_7706021_12 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 377.0
HFD3_k127_7706021_13 Amino acid kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 308.0
HFD3_k127_7706021_14 Response regulator receiver K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004365 274.0
HFD3_k127_7706021_15 MDMPI C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000001743 200.0
HFD3_k127_7706021_16 - - - - 0.00000000000000000000000000000000001123 143.0
HFD3_k127_7706021_17 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division - GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000001689 115.0
HFD3_k127_7706021_18 Acetyltransferase (GNAT) domain - - - 0.000000000000000000008624 108.0
HFD3_k127_7706021_19 AAA domain - - - 0.000004035 51.0
HFD3_k127_7706021_2 ATPases associated with a variety of cellular activities K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 578.0
HFD3_k127_7706021_3 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 509.0
HFD3_k127_7706021_4 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 489.0
HFD3_k127_7706021_5 VWA containing CoxE family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 469.0
HFD3_k127_7706021_6 PFAM binding-protein-dependent transport systems inner membrane component K10233 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 460.0
HFD3_k127_7706021_7 ABC transporter substrate-binding protein K10232 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 437.0
HFD3_k127_7706021_8 PFAM binding-protein-dependent transport systems inner membrane component K10234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006809 416.0
HFD3_k127_7706021_9 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 378.0
HFD3_k127_7732721_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006793,GO:0006796,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:0071944,GO:1902494,GO:1902503,GO:1990234 2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 581.0
HFD3_k127_7732721_1 sulfate adenylyltransferase K00957 GO:0000103,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:1902494,GO:1902503,GO:1990234 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 451.0
HFD3_k127_7732721_10 Choline/ethanolamine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003553 269.0
HFD3_k127_7732721_11 glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004611 270.0
HFD3_k127_7732721_12 cell adhesion involved in biofilm formation K13735,K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002716 272.0
HFD3_k127_7732721_13 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000001445 244.0
HFD3_k127_7732721_14 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002615 257.0
HFD3_k127_7732721_15 PFAM F5 8 type C domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001531 255.0
HFD3_k127_7732721_16 outer membrane autotransporter barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001176 247.0
HFD3_k127_7732721_17 Catalyzes the synthesis of activated sulfate K00955,K00956 GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006793,GO:0006796,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:0071944,GO:1902494,GO:1902503,GO:1990234 2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000658 229.0
HFD3_k127_7732721_18 - - - - 0.00000000000000000000000000000000000000000000000000000000008929 217.0
HFD3_k127_7732721_19 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000003091 204.0
HFD3_k127_7732721_2 helix_turn _helix lactose operon repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 441.0
HFD3_k127_7732721_20 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000002122 201.0
HFD3_k127_7732721_21 FR47-like protein - - - 0.00000000000000000000000000000000000000000000000000006692 198.0
HFD3_k127_7732721_22 protein phosphatase 2C domain protein - - - 0.000000000000000000000000000000000000000000000000000747 212.0
HFD3_k127_7732721_23 - - - - 0.000000000000000000000000000000000000000000000007898 187.0
HFD3_k127_7732721_24 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors - - - 0.0000000000000000000000000000000000000000001797 170.0
HFD3_k127_7732721_25 outer membrane autotransporter barrel domain protein - - - 0.000000000000000000000000000000000000000009156 171.0
HFD3_k127_7732721_26 PFAM Glycosyl transferase family 2 K16870 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0045226,GO:0046379,GO:0071704,GO:0071944,GO:1901576 2.4.1.289 0.000000000000000000000000000000000000231 158.0
HFD3_k127_7732721_27 transcriptional regulator - - - 0.0000000000000000000000000000000005407 138.0
HFD3_k127_7732721_28 LuxR family transcriptional regulator - - - 0.000000000000000000000000000000001472 140.0
HFD3_k127_7732721_29 Transcriptional regulator - - - 0.0000000000000000000000000000001468 137.0
HFD3_k127_7732721_3 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 421.0
HFD3_k127_7732721_30 Competence-damaged protein K03743 - 3.5.1.42 0.00000000000000000000000003535 113.0
HFD3_k127_7732721_31 Pkd domain containing protein - - - 0.00000000000000000002752 92.0
HFD3_k127_7732721_32 antisigma factor binding K04749 - - 0.000000000000000003183 87.0
HFD3_k127_7732721_33 diguanylate cyclase - - - 0.000000000000002366 86.0
HFD3_k127_7732721_34 AMP binding - - - 0.000000002353 65.0
HFD3_k127_7732721_35 transferase activity, transferring glycosyl groups K20276 - - 0.000000004586 71.0
HFD3_k127_7732721_36 anti-sigma regulatory factor K04757 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036094,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 2.7.11.1 0.0000005596 56.0
HFD3_k127_7732721_37 Sigma factor PP2C-like phosphatases - - - 0.0001282 51.0
HFD3_k127_7732721_4 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 369.0
HFD3_k127_7732721_5 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 374.0
HFD3_k127_7732721_6 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006852 314.0
HFD3_k127_7732721_7 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 294.0
HFD3_k127_7732721_8 belongs to the sigma-70 factor family K03090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000255 285.0
HFD3_k127_7732721_9 PFAM F5 8 type C domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002051 285.0
HFD3_k127_786125_0 DNA polymerase alpha chain like domain K02337 - 2.7.7.7 0.0 1751.0
HFD3_k127_786125_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0 1454.0
HFD3_k127_786125_10 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 416.0
HFD3_k127_786125_11 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000881 438.0
HFD3_k127_786125_12 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000767 414.0
HFD3_k127_786125_13 Cell cycle protein K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005394 395.0
HFD3_k127_786125_14 Bacterial lipid A biosynthesis acyltransferase K22311 - 2.3.1.265 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 376.0
HFD3_k127_786125_15 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008511 365.0
HFD3_k127_786125_16 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 361.0
HFD3_k127_786125_17 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 358.0
HFD3_k127_786125_18 Serine threonine protein kinase involved in cell cycle control K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005451 315.0
HFD3_k127_786125_19 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 309.0
HFD3_k127_786125_2 Protein of unknown function, DUF255 K06888 - - 1.204e-270 850.0
HFD3_k127_786125_20 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 332.0
HFD3_k127_786125_21 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 295.0
HFD3_k127_786125_22 Acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000001814 269.0
HFD3_k127_786125_23 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000002094 237.0
HFD3_k127_786125_24 HIT domain K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000000000000000000000003422 232.0
HFD3_k127_786125_25 - - - - 0.00000000000000000000000000000000000000000000000000000000000406 213.0
HFD3_k127_786125_26 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000008018 214.0
HFD3_k127_786125_27 Alanine racemase, N-terminal domain K06997 - - 0.000000000000000000000000000000000000000000000000000000002662 217.0
HFD3_k127_786125_28 regulation of cell shape - - - 0.000000000000000000000000000000000000000000000000000001393 203.0
HFD3_k127_786125_29 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA K09772 - - 0.0000000000000000000000000000000000000000000000000003847 192.0
HFD3_k127_786125_3 Threonyl and Alanyl tRNA synthetase second additional domain K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 9.637e-229 725.0
HFD3_k127_786125_30 Protein of unknown function (DUF2587) - - - 0.0000000000000000000000000000000000000000000000000004446 189.0
HFD3_k127_786125_31 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589,K06438 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 6.3.2.4 0.0000000000000000000000000000000000000000000000001076 195.0
HFD3_k127_786125_32 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters - - - 0.0000000000000000000000000000000000000000000000003585 186.0
HFD3_k127_786125_33 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000001084 165.0
HFD3_k127_786125_34 ANTAR - - - 0.0000000000000000000000000000000000000000002725 168.0
HFD3_k127_786125_35 Nitroreductase family - - - 0.0000000000000000000000000000000000000007404 163.0
HFD3_k127_786125_36 Belongs to the anti-sigma-factor antagonist family K06378 - - 0.0000003658 60.0
HFD3_k127_786125_4 Belongs to the MurCDEF family K01924 - 6.3.2.8 1.156e-203 653.0
HFD3_k127_786125_5 tRNA synthetases class I (C) catalytic domain K15526 - 6.3.1.13 1.358e-199 629.0
HFD3_k127_786125_6 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007174 577.0
HFD3_k127_786125_7 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 483.0
HFD3_k127_786125_8 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 478.0
HFD3_k127_786125_9 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 447.0
HFD3_k127_805726_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K14441 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0035596,GO:0035599,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006919 599.0
HFD3_k127_805726_1 Competence-damaged protein K03742 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 373.0
HFD3_k127_805726_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000001854 234.0
HFD3_k127_810442_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 4.585e-239 761.0
HFD3_k127_810442_1 Arginosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 3.516e-228 713.0
HFD3_k127_810442_10 RarD protein K05786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000122 263.0
HFD3_k127_810442_11 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000001284 224.0
HFD3_k127_810442_12 Phosphoglucose isomerase K01810 - 5.3.1.9 0.000000000000000000000000000000000000000000000000002067 193.0
HFD3_k127_810442_13 Transposase - - - 0.0000000000000000000000000000000000000000000000005196 182.0
HFD3_k127_810442_14 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000001125 177.0
HFD3_k127_810442_15 Domain of unknown function (DUF305) - - - 0.000000000000000000000000000008164 127.0
HFD3_k127_810442_16 NMT1-like family - - - 0.0000000000000000000000000001902 130.0
HFD3_k127_810442_18 SnoaL-like domain - - - 0.00000000000000000002733 94.0
HFD3_k127_810442_19 Cytochrome c - - - 0.0000000009862 64.0
HFD3_k127_810442_2 Belongs to the GPI family K01810 GO:0003674,GO:0003824,GO:0004347,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 1.044e-214 681.0
HFD3_k127_810442_20 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000004425 49.0
HFD3_k127_810442_3 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 GO:0000271,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901576 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 581.0
HFD3_k127_810442_4 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 474.0
HFD3_k127_810442_5 Ppx GppA phosphatase K01524 GO:0003674,GO:0003824,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006093 451.0
HFD3_k127_810442_6 peptidase K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007335 433.0
HFD3_k127_810442_7 Glycosyl transferase, family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008572 348.0
HFD3_k127_810442_8 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 298.0
HFD3_k127_810442_9 neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001305 285.0
HFD3_k127_814925_0 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA K00674 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008666,GO:0016020,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0030312,GO:0031402,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0071944 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 398.0
HFD3_k127_814925_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 388.0
HFD3_k127_814925_2 serine-type endopeptidase activity K04771 GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 291.0
HFD3_k127_814925_3 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001094 271.0
HFD3_k127_814925_4 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000000000000000000000000000000000000001022 175.0
HFD3_k127_814925_5 regulation of RNA biosynthetic process - - - 0.00000000000000000000000000000000002834 139.0
HFD3_k127_814925_6 Iron-containing redox enzyme K06137 - 1.3.3.11 0.0000000004312 69.0
HFD3_k127_814925_7 Sortase family K07284 - 3.4.22.70 0.00000001907 64.0
HFD3_k127_821255_0 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 612.0
HFD3_k127_821255_1 Domain of unknown function (DUF4162) K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005519 442.0
HFD3_k127_821255_10 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000005294 253.0
HFD3_k127_821255_11 helix_turn_helix ASNC type - - - 0.00000000000000000000000000000000000000000006128 170.0
HFD3_k127_821255_12 Transcriptional regulator - - - 0.000000000000000000000000000000000000000005054 160.0
HFD3_k127_821255_13 cell cycle K05589,K13052 - - 0.0000000000000000000000001716 112.0
HFD3_k127_821255_14 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000141 72.0
HFD3_k127_821255_15 antisigma factor binding K04749 - - 0.000000001178 65.0
HFD3_k127_821255_2 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008272,GO:0015698,GO:0016020,GO:0040007,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0072348 3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 438.0
HFD3_k127_821255_3 sulfate ABC transporter K02048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 408.0
HFD3_k127_821255_4 Binding-protein-dependent transport systems inner membrane component K02018,K15496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 339.0
HFD3_k127_821255_5 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005056 329.0
HFD3_k127_821255_6 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 320.0
HFD3_k127_821255_7 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005116 308.0
HFD3_k127_821255_8 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001522 267.0
HFD3_k127_821255_9 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001248 252.0
HFD3_k127_822702_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 1.391e-291 906.0
HFD3_k127_822702_1 Succinyl-CoA ligase like flavodoxin domain - - - 2.81e-230 743.0
HFD3_k127_822702_10 Calcineurin-like phosphoesterase K03651 - 3.1.4.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 434.0
HFD3_k127_822702_11 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007111 416.0
HFD3_k127_822702_12 response to copper ion K07156,K07245,K14166 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 423.0
HFD3_k127_822702_13 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 370.0
HFD3_k127_822702_14 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 357.0
HFD3_k127_822702_15 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 327.0
HFD3_k127_822702_16 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 335.0
HFD3_k127_822702_17 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 343.0
HFD3_k127_822702_18 Protein of unknown function (DUF3500) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007473 340.0
HFD3_k127_822702_19 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 311.0
HFD3_k127_822702_2 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 8.042e-216 689.0
HFD3_k127_822702_20 Branched-chain amino acid transport K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 314.0
HFD3_k127_822702_21 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004746 295.0
HFD3_k127_822702_22 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 290.0
HFD3_k127_822702_23 Periplasmic binding protein K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006872 293.0
HFD3_k127_822702_24 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001922 272.0
HFD3_k127_822702_25 Belongs to the peptidase M50B family - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003414 279.0
HFD3_k127_822702_26 Branched-chain amino acid ATP-binding cassette transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001397 292.0
HFD3_k127_822702_27 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000473 270.0
HFD3_k127_822702_28 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001286 264.0
HFD3_k127_822702_29 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000000000000000147 256.0
HFD3_k127_822702_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008309 596.0
HFD3_k127_822702_31 Pyridoxamine 5'-phosphate K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000000002019 249.0
HFD3_k127_822702_32 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000164 227.0
HFD3_k127_822702_33 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000003309 230.0
HFD3_k127_822702_34 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000007639 212.0
HFD3_k127_822702_35 Peptidase C26 - - - 0.00000000000000000000000000000000000000000000000000000000001769 214.0
HFD3_k127_822702_36 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.00000000000000000000000000000000000000000000000000000004275 199.0
HFD3_k127_822702_37 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000005008 215.0
HFD3_k127_822702_38 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000001799 187.0
HFD3_k127_822702_39 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.000000000000000000000000000000000000000000000005131 184.0
HFD3_k127_822702_4 L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 549.0
HFD3_k127_822702_40 MgtC family K07507 - - 0.0000000000000000000000000000000000000000000001607 184.0
HFD3_k127_822702_41 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000001812 177.0
HFD3_k127_822702_42 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000002194 168.0
HFD3_k127_822702_43 Universal stress protein family - - - 0.000000000000000000000000000000000000000006185 166.0
HFD3_k127_822702_44 - - - - 0.0000000000000000000000000000000000000004317 158.0
HFD3_k127_822702_45 Protein of unknown function (DUF664) - - - 0.00000000000000000000000000000000000001151 151.0
HFD3_k127_822702_46 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000004722 158.0
HFD3_k127_822702_47 Inositol monophosphatase family K05602 - 3.1.3.15 0.000000000000000000000000000000000000214 164.0
HFD3_k127_822702_48 Acetyltransferase, GNAT K06977 - - 0.0000000000000000000000000000000000008664 145.0
HFD3_k127_822702_49 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000302 143.0
HFD3_k127_822702_5 Aldo Keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 523.0
HFD3_k127_822702_50 FMN binding K03809 - 1.6.5.2 0.0000000000000000000000000000000002059 139.0
HFD3_k127_822702_51 Belongs to the small heat shock protein (HSP20) family K13993 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016310,GO:0019538,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0036294,GO:0040007,GO:0040008,GO:0042221,GO:0042594,GO:0043170,GO:0043207,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045926,GO:0046777,GO:0048519,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071496,GO:0071704,GO:0071944,GO:0075136,GO:1901564 - 0.000000000000000000000000000007239 124.0
HFD3_k127_822702_52 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000001498 129.0
HFD3_k127_822702_53 Sigma-70 region 2 - - - 0.00000000000000000000000000002986 125.0
HFD3_k127_822702_54 translation release factor activity - - - 0.00000000000000000000000001211 123.0
HFD3_k127_822702_55 Protein of unknown function (DUF541) K09807 - - 0.0000000000000000000000005248 114.0
HFD3_k127_822702_56 Nucleoside 2-deoxyribosyltransferase like K08728 - 2.4.2.6 0.000000000000000000005482 100.0
HFD3_k127_822702_57 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000222 101.0
HFD3_k127_822702_58 Histidine kinase K07711,K19694 - 2.7.13.3 0.000000000000000002834 97.0
HFD3_k127_822702_59 PFAM Sporulation and spore germination - - - 0.00000000000000007439 92.0
HFD3_k127_822702_6 Aminotransferase K00812,K14267 - 2.6.1.1,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005289 523.0
HFD3_k127_822702_60 CBS domains - - - 0.0000000000000003995 83.0
HFD3_k127_822702_62 Cupredoxin-like domain - - - 0.0000001087 60.0
HFD3_k127_822702_63 - - - - 0.0000001619 64.0
HFD3_k127_822702_64 AMP binding - - - 0.000000743 59.0
HFD3_k127_822702_65 Methyltransferase type 11 - - - 0.00001035 48.0
HFD3_k127_822702_66 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00001208 48.0
HFD3_k127_822702_67 ERCC4 domain - - - 0.00004446 49.0
HFD3_k127_822702_7 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00758 - 2.4.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 507.0
HFD3_k127_822702_8 dna ligase - GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 476.0
HFD3_k127_822702_9 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009953 464.0
HFD3_k127_911712_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2050.0
HFD3_k127_911712_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 5.162e-231 720.0
HFD3_k127_911712_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007214 334.0
HFD3_k127_911712_3 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 327.0
HFD3_k127_911712_4 helix_turn _helix lactose operon repressor K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 328.0
HFD3_k127_911712_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000003773 211.0
HFD3_k127_911712_6 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000000009086 203.0
HFD3_k127_911712_7 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000003728 158.0
HFD3_k127_911712_8 Acetyltransferase (GNAT) domain - - - 0.000008182 58.0
HFD3_k127_911712_9 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00002197 50.0
HFD3_k127_923858_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 1.41e-279 868.0
HFD3_k127_923858_1 glutamine synthetase K01915 - 6.3.1.2 5.31e-229 716.0
HFD3_k127_923858_10 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 376.0
HFD3_k127_923858_11 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 311.0
HFD3_k127_923858_12 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 292.0
HFD3_k127_923858_13 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001092 230.0
HFD3_k127_923858_14 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000002966 226.0
HFD3_k127_923858_15 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000001421 241.0
HFD3_k127_923858_16 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K15580 - - 0.00000000000000000000000000000000000000000000000006551 201.0
HFD3_k127_923858_17 PFAM periplasmic binding protein LacI transcriptional regulator K03604,K05499 - - 0.0000000000000000000000000000000000000003361 162.0
HFD3_k127_923858_18 MazG nucleotide pyrophosphohydrolase domain - - - 0.0000000000000000000000000000000000001084 147.0
HFD3_k127_923858_19 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000006547 128.0
HFD3_k127_923858_2 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 4.784e-228 725.0
HFD3_k127_923858_20 - - - - 0.000000000000103 81.0
HFD3_k127_923858_3 pyrroloquinoline quinone binding - - - 9.284e-203 659.0
HFD3_k127_923858_4 ACT domain K00928 - 2.7.2.4 2.031e-198 625.0
HFD3_k127_923858_5 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 GO:0003674,GO:0003824,GO:0004073,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008095 527.0
HFD3_k127_923858_6 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 482.0
HFD3_k127_923858_7 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006564 471.0
HFD3_k127_923858_8 Cys/Met metabolism PLP-dependent enzyme K19715 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0016051,GO:0043170,GO:0044238,GO:0071704,GO:1901576 2.6.1.109 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005611 415.0
HFD3_k127_923858_9 Belongs to the Glu Leu Phe Val dehydrogenases family K00270 - 1.4.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 394.0
HFD3_k127_959238_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1362.0
HFD3_k127_959238_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006986 524.0
HFD3_k127_959238_10 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 378.0
HFD3_k127_959238_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 306.0
HFD3_k127_959238_12 ABC transporter K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 306.0
HFD3_k127_959238_13 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 301.0
HFD3_k127_959238_14 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 296.0
HFD3_k127_959238_15 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003104 282.0
HFD3_k127_959238_16 Protein of unknown function (DUF459) K09795 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005469 268.0
HFD3_k127_959238_17 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000002288 259.0
HFD3_k127_959238_18 Carbon monoxide dehydrogenase subunit G (CoxG) K09386 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006367 245.0
HFD3_k127_959238_19 Protein of unknown function (DUF501) K09009 - - 0.00000000000000000000000000000000000000000000002365 178.0
HFD3_k127_959238_2 Belongs to the glycosyl hydrolase 13 family K01214,K02438 - 3.2.1.196,3.2.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007597 476.0
HFD3_k127_959238_20 MobA-like NTP transferase domain K07141,K19190 - 1.1.1.328,2.7.7.76 0.00000000000000000000000000000000000000001151 160.0
HFD3_k127_959238_21 Universal stress protein family - - - 0.00000000000000000000000000000000000002896 155.0
HFD3_k127_959238_22 cysteine-type peptidase activity K21471 - - 0.000000000000000000000000000000000001095 148.0
HFD3_k127_959238_23 Universal stress protein family - - - 0.000000000000000000000000000000000001142 152.0
HFD3_k127_959238_24 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.00000000000000000000000000000006919 128.0
HFD3_k127_959238_26 Ppx GppA phosphatase - - - 0.00000000000000000000002572 111.0
HFD3_k127_959238_27 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000002262 76.0
HFD3_k127_959238_28 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00001965 48.0
HFD3_k127_959238_3 von Willebrand factor (vWF) type A domain K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009565 463.0
HFD3_k127_959238_4 XdhC Rossmann domain K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 430.0
HFD3_k127_959238_5 ATPase associated with various cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 430.0
HFD3_k127_959238_6 AAA domain (dynein-related subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004242 438.0
HFD3_k127_959238_7 Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009681 397.0
HFD3_k127_959238_8 von Willebrand factor, type A K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 394.0
HFD3_k127_959238_9 Belongs to the enoyl-CoA hydratase isomerase family K01692 GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 376.0
HFD3_k127_961517_0 cytochrome P-450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 435.0
HFD3_k127_961517_1 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 383.0
HFD3_k127_961517_2 leucyl aminopeptidase, aminopeptidase T K18028 - 1.13.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006558 355.0
HFD3_k127_961517_3 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 311.0
HFD3_k127_961517_4 Fumarylacetoacetate (FAA) hydrolase family K05921 - 4.1.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000006977 239.0
HFD3_k127_961517_5 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000001171 231.0
HFD3_k127_961517_6 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000003546 217.0
HFD3_k127_961517_7 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000149 178.0
HFD3_k127_962384_0 PFAM Glycoside hydrolase, family 38 K01191 - 3.2.1.24 0.0 1023.0
HFD3_k127_962384_1 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 602.0
HFD3_k127_962384_10 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006268 425.0
HFD3_k127_962384_11 PFAM Bacterial regulatory protein, arsR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 321.0
HFD3_k127_962384_12 dna ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 315.0
HFD3_k127_962384_13 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 303.0
HFD3_k127_962384_14 MATE efflux family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 312.0
HFD3_k127_962384_15 N-6 DNA Methylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 310.0
HFD3_k127_962384_16 oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 292.0
HFD3_k127_962384_17 hydrolase K07025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001785 266.0
HFD3_k127_962384_18 Protein synonym peptidase M K01265 GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564,GO:1901605 3.4.11.18 0.00000000000000000000000000000000000000000002589 162.0
HFD3_k127_962384_19 HTH domain - - - 0.0000000000000000000000000000000000000000001877 166.0
HFD3_k127_962384_2 Pfam Sulfatase K01133 - 3.1.6.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 595.0
HFD3_k127_962384_20 Protein of unknown function (DUF1203) - - - 0.0000000000000000000000000000000000000000002564 164.0
HFD3_k127_962384_21 GGDEF domain - - - 0.00000000000000000000000000000000005986 148.0
HFD3_k127_962384_22 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000007331 141.0
HFD3_k127_962384_23 Nudix hydrolase K01823 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 5.3.3.2 0.000000000000000000000000000001906 128.0
HFD3_k127_962384_24 Hemerythrin HHE cation binding domain - - - 0.00000000000000005189 87.0
HFD3_k127_962384_27 Thiamine-binding protein - - - 0.0000000003455 64.0
HFD3_k127_962384_3 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 539.0
HFD3_k127_962384_4 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 510.0
HFD3_k127_962384_5 (Pantothenic acid kinase)) K00867 GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 455.0
HFD3_k127_962384_6 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 462.0
HFD3_k127_962384_7 PFAM Peptidase family M20 M25 M40 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 443.0
HFD3_k127_962384_8 involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 449.0
HFD3_k127_962384_9 Response regulator receiver modulated diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 440.0
HFD3_k127_998657_0 Belongs to the thiolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 546.0
HFD3_k127_998657_1 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009206 434.0
HFD3_k127_998657_10 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104,K01808,K07566,K20201 - 2.7.7.87,3.1.3.48,3.9.1.2,5.3.1.6 0.0000000000000000000000000000002689 128.0
HFD3_k127_998657_11 dipeptide transport K02035 - - 0.000000000000059 84.0
HFD3_k127_998657_13 Glycosyl hydrolases family 25 K07273 - - 0.0003003 53.0
HFD3_k127_998657_2 Zinc-binding dehydrogenase K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 361.0
HFD3_k127_998657_3 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 341.0
HFD3_k127_998657_4 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 315.0
HFD3_k127_998657_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001487 285.0
HFD3_k127_998657_6 Enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001335 242.0
HFD3_k127_998657_7 cytochrome complex assembly K02200,K04018 - - 0.00000000000000000000000000000000000000000000000000000000000000005035 244.0
HFD3_k127_998657_8 C-terminal four TMM region of protein-O-mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000006652 192.0