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Overview

ID MAG01688
Name HFD3_bin.30
Sample SMP0045
Taxonomy
Kingdom Bacteria
Phylum Methylomirabilota
Class Methylomirabilia
Order Rokubacteriales
Family CSP1-6
Genus
Species
Assembly information
Completeness (%) 88.55
Contamination (%) 2.11
GC content (%) 70.0
N50 (bp) 19,262
Genome size (bp) 5,451,429

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes4967

Gene name Description KEGG GOs EC E-value Score Sequence
HFD3_k127_1036080_0 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 424.0
HFD3_k127_1036080_1 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 374.0
HFD3_k127_1036080_4 Phosphoglycerate mutase - - - 0.0000000000000000002128 96.0
HFD3_k127_1068702_0 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 4.41e-203 643.0
HFD3_k127_1068702_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004601 461.0
HFD3_k127_1068702_10 'PFAM Taurine catabolism dioxygenase TauD, TfdA family' - - - 0.0000004411 55.0
HFD3_k127_1068702_11 Luciferase-like monooxygenase - - - 0.00002735 50.0
HFD3_k127_1068702_12 ROK family K00845 - 2.7.1.2 0.0002965 53.0
HFD3_k127_1068702_2 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 349.0
HFD3_k127_1068702_3 amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009755 325.0
HFD3_k127_1068702_4 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000004489 222.0
HFD3_k127_1068702_5 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000001509 183.0
HFD3_k127_1068702_6 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000000000000000000001024 170.0
HFD3_k127_1068702_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000001684 106.0
HFD3_k127_1068702_8 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.0000000000000005292 90.0
HFD3_k127_1068702_9 'PFAM Taurine catabolism dioxygenase TauD, TfdA family' - - - 0.0000000976 57.0
HFD3_k127_1081689_0 KaiC K08482 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 319.0
HFD3_k127_1081689_1 PhoQ Sensor - - - 0.0000000003268 66.0
HFD3_k127_1081689_2 START domain - - - 0.000002067 55.0
HFD3_k127_1113332_0 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008893 560.0
HFD3_k127_1113332_1 PFAM ABC transporter related K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 345.0
HFD3_k127_1113332_2 Glutamate aspartate transport system permease protein GltJ K02029,K10003 - - 0.0000000000000000000000000000000000000000000000000000000000001127 221.0
HFD3_k127_1113332_3 Bacterial periplasmic substrate-binding proteins K02030,K10001 - - 0.00000000000000000000000000000000000000000000000000004037 207.0
HFD3_k127_1113332_4 PFAM binding-protein-dependent transport systems inner membrane component K02029,K10002 - - 0.00000000000000000000000000000000000000000000000000006131 195.0
HFD3_k127_1113332_5 THIoesterase K18700 - 3.1.2.29 0.000000000000000000000000001491 116.0
HFD3_k127_1113332_6 Biotin-lipoyl like K01960,K01965,K01968 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.1,6.4.1.3,6.4.1.4 0.00000000000000000000003971 116.0
HFD3_k127_1113332_7 Serine aminopeptidase, S33 K01055 - 3.1.1.24 0.0000000000000004796 90.0
HFD3_k127_1114190_0 Radical SAM - - - 2.489e-211 666.0
HFD3_k127_1114190_1 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 620.0
HFD3_k127_1114190_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 307.0
HFD3_k127_1114190_11 Psort location Cytoplasmic, score K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004535 271.0
HFD3_k127_1114190_12 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000466 287.0
HFD3_k127_1114190_13 Bacterial type II and III secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001064 281.0
HFD3_k127_1114190_14 Belongs to the 3-hydroxyisobutyrate dehydrogenase family K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000009831 253.0
HFD3_k127_1114190_15 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000000000000000000000000000000000000006023 254.0
HFD3_k127_1114190_16 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000002932 207.0
HFD3_k127_1114190_17 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003,K05685 - - 0.0000000000000000000000000000000000000000000000000006331 194.0
HFD3_k127_1114190_18 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.0000000000000000000000000000000000000000000000001903 186.0
HFD3_k127_1114190_19 Type II secretion system (T2SS), protein G K02456 - - 0.000000000000000000000000000000000000000000004623 169.0
HFD3_k127_1114190_2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 509.0
HFD3_k127_1114190_20 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000009581 169.0
HFD3_k127_1114190_21 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000003918 170.0
HFD3_k127_1114190_22 PFAM Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000001895 174.0
HFD3_k127_1114190_23 PFAM Glycosyl transferase, family 39 - - - 0.000000000000000000000000000000000000003045 166.0
HFD3_k127_1114190_24 Cupin 2, conserved barrel domain protein K00971,K01809,K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000001835 136.0
HFD3_k127_1114190_25 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000002351 138.0
HFD3_k127_1114190_26 spore germination K03298 - - 0.00000000000000000000000000002809 134.0
HFD3_k127_1114190_27 Glyoxalase-like domain K01759,K01849,K05606 - 4.4.1.5,5.1.99.1,5.4.99.2 0.00000000000000000000000000004715 126.0
HFD3_k127_1114190_28 GYD domain - - - 0.000000000000000000000000001472 121.0
HFD3_k127_1114190_29 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000008603 115.0
HFD3_k127_1114190_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 478.0
HFD3_k127_1114190_30 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.00000000000000000000001583 117.0
HFD3_k127_1114190_31 Type II secretion system (T2SS), protein K K02460 - - 0.0000000000000000000002948 113.0
HFD3_k127_1114190_32 Gram-negative-bacterium-type cell wall biogenesis - - - 0.0000000000000000362 91.0
HFD3_k127_1114190_33 response regulator - - - 0.00000000000001022 83.0
HFD3_k127_1114190_34 Fimbrial assembly protein (PilN) K02461 - - 0.00000000000003651 85.0
HFD3_k127_1114190_35 Prokaryotic N-terminal methylation motif K02456,K02457,K02458,K02459,K02655,K10926 - - 0.000000005542 65.0
HFD3_k127_1114190_36 Type II secretion system (T2SS), protein M subtype b K02462 - - 0.00000001015 64.0
HFD3_k127_1114190_37 Prokaryotic N-terminal methylation motif K02458 - - 0.0000006392 61.0
HFD3_k127_1114190_38 general secretion pathway protein K02457 - - 0.0000008589 57.0
HFD3_k127_1114190_39 - - - - 0.000000983 56.0
HFD3_k127_1114190_4 MFS_1 like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 449.0
HFD3_k127_1114190_40 - - - - 0.00003173 55.0
HFD3_k127_1114190_41 Cyclic nucleotide-monophosphate binding domain - - - 0.00006473 53.0
HFD3_k127_1114190_42 - - - - 0.00008549 55.0
HFD3_k127_1114190_43 ThiS family K03636 - - 0.0002151 49.0
HFD3_k127_1114190_5 Type II secretion system (T2SS), protein F K02455,K02653 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 370.0
HFD3_k127_1114190_6 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 359.0
HFD3_k127_1114190_7 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 366.0
HFD3_k127_1114190_8 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 GO:0000255,GO:0000256,GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008679,GO:0009056,GO:0009436,GO:0009442,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042737,GO:0043436,GO:0043603,GO:0043605,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046483,GO:0046487,GO:0046700,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.1.1.31,1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 325.0
HFD3_k127_1114190_9 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 322.0
HFD3_k127_1122901_0 Putative modulator of DNA gyrase K03568 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 602.0
HFD3_k127_1122901_1 Putative modulator of DNA gyrase K03592 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 462.0
HFD3_k127_1122901_2 Peptidase family M28 K01258 - 3.4.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 345.0
HFD3_k127_1122901_3 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 293.0
HFD3_k127_1122901_4 ABC transporter substrate-binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003826 266.0
HFD3_k127_1122901_5 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000003548 189.0
HFD3_k127_1122901_6 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000001588 188.0
HFD3_k127_1122901_7 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000001099 101.0
HFD3_k127_1146567_0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214 - 3.2.1.68 0.0 1009.0
HFD3_k127_1146567_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 2.248e-298 932.0
HFD3_k127_1146567_10 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000001088 179.0
HFD3_k127_1146567_11 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000002632 154.0
HFD3_k127_1146567_13 Cupin 4 family protein K18850 - 1.14.11.47 0.0000002035 64.0
HFD3_k127_1146567_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 602.0
HFD3_k127_1146567_3 Belongs to the Glu Leu Phe Val dehydrogenases family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 505.0
HFD3_k127_1146567_4 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007087 399.0
HFD3_k127_1146567_5 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005388 320.0
HFD3_k127_1146567_6 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004406 296.0
HFD3_k127_1146567_7 Amino acid synthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007113 261.0
HFD3_k127_1146567_8 Cell shape determining protein MreB Mrl K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008191 273.0
HFD3_k127_1146567_9 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000005676 191.0
HFD3_k127_1146983_0 sigma-54 factor interaction domain-containing protein K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 398.0
HFD3_k127_1146983_1 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 392.0
HFD3_k127_1146983_10 - - - - 0.000000000000000000000000000000005515 134.0
HFD3_k127_1146983_11 Putative zinc-finger - - - 0.000000000000000000000000000006789 134.0
HFD3_k127_1146983_12 YMGG-like Gly-zipper - - - 0.00000000000000000000000000114 120.0
HFD3_k127_1146983_13 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000000000000003776 104.0
HFD3_k127_1146983_14 cheY-homologous receiver domain - - - 0.0000000000000000009602 101.0
HFD3_k127_1146983_15 - - - - 0.000000000000000001395 94.0
HFD3_k127_1146983_16 Carbohydrate-selective porin, OprB family - - - 0.000394 49.0
HFD3_k127_1146983_17 Protein of unknown function (DUF1634) - - - 0.0009979 51.0
HFD3_k127_1146983_2 PFAM amidohydrolase 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009116 371.0
HFD3_k127_1146983_3 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 359.0
HFD3_k127_1146983_4 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 346.0
HFD3_k127_1146983_5 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 302.0
HFD3_k127_1146983_6 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008035 255.0
HFD3_k127_1146983_7 F420H(2)-dependent quinone reductase - - - 0.000000000000000000000000000000000000000000000000000000003001 214.0
HFD3_k127_1146983_8 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000001679 202.0
HFD3_k127_1146983_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000002306 151.0
HFD3_k127_1156359_0 lipopolysaccharide transport K22110 - - 0.0 1169.0
HFD3_k127_1156359_1 Belongs to the GPI family K01810 - 5.3.1.9 2.797e-272 866.0
HFD3_k127_1156359_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 2.031e-209 661.0
HFD3_k127_1156359_3 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 520.0
HFD3_k127_1156359_4 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 480.0
HFD3_k127_1156359_5 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006984 380.0
HFD3_k127_1156359_6 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000007958 198.0
HFD3_k127_1156359_7 Phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.00000000000000000000000000000004112 126.0
HFD3_k127_1157985_0 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006829 441.0
HFD3_k127_1157985_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 435.0
HFD3_k127_1157985_10 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000001844 240.0
HFD3_k127_1157985_11 Class II aldolase - - - 0.0000000000000000000000000000000000000000000007189 183.0
HFD3_k127_1157985_12 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0000000000000000000000000000000000007189 150.0
HFD3_k127_1157985_13 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000001148 140.0
HFD3_k127_1157985_14 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 0.000000000000002894 85.0
HFD3_k127_1157985_2 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 399.0
HFD3_k127_1157985_3 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 376.0
HFD3_k127_1157985_4 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 329.0
HFD3_k127_1157985_5 HpcH/HpaI aldolase/citrate lyase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006934 315.0
HFD3_k127_1157985_6 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 295.0
HFD3_k127_1157985_7 Oxidoreductase family, NAD-binding Rossmann fold K10219 - 1.1.1.312 0.0000000000000000000000000000000000000000000000000000000000000000000007286 243.0
HFD3_k127_1157985_8 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000005634 243.0
HFD3_k127_1157985_9 KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000000000000000000000000000000000000000000000000003933 228.0
HFD3_k127_1183803_0 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 456.0
HFD3_k127_1183803_1 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000005217 127.0
HFD3_k127_1183803_2 - - - - 0.00000000000000000000000139 111.0
HFD3_k127_1183803_3 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000001971 100.0
HFD3_k127_1183803_4 Bacterial antitoxin of type II TA system, VapB - - - 0.000000000004557 69.0
HFD3_k127_1202442_0 ABC-type uncharacterized transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 522.0
HFD3_k127_1202442_1 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 291.0
HFD3_k127_1202442_2 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000006551 250.0
HFD3_k127_1202442_3 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000002314 104.0
HFD3_k127_1202442_4 Domain of unknown function (DUF4340) - - - 0.000000000000000004294 99.0
HFD3_k127_121704_0 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 310.0
HFD3_k127_121704_1 MMPL family - - - 0.00000000000000000000000000000000000000000001747 165.0
HFD3_k127_122359_0 Serves to protect cells from the toxic effects of hydrogen peroxide K03781 - 1.11.1.6 8.875e-260 809.0
HFD3_k127_122359_1 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004074 545.0
HFD3_k127_122359_10 PFAM response regulator receiver K02483,K07658,K07668 - - 0.0000000000000000000000000000000000000000000000000000000000000000004195 239.0
HFD3_k127_122359_11 Thioredoxin - - - 0.000000000000000000000000000000001777 134.0
HFD3_k127_122359_12 Bacterial protein of unknown function (DUF839) K07093 - - 0.0005687 47.0
HFD3_k127_122359_2 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006844 395.0
HFD3_k127_122359_3 MmgE/PrpD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006831 394.0
HFD3_k127_122359_4 Polysaccharide deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 380.0
HFD3_k127_122359_5 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 GO:0003674,GO:0005215,GO:0005372,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006833,GO:0006884,GO:0006950,GO:0006970,GO:0008150,GO:0008361,GO:0009628,GO:0009987,GO:0009992,GO:0015250,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0042044,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0050896,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007993 368.0
HFD3_k127_122359_6 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 365.0
HFD3_k127_122359_7 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 361.0
HFD3_k127_122359_8 Binding-protein-dependent transport system inner membrane component K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 314.0
HFD3_k127_122359_9 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007031 269.0
HFD3_k127_1245546_0 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 479.0
HFD3_k127_1245546_1 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008944 463.0
HFD3_k127_1245546_10 Glycine-zipper domain - - - 0.0000000000000000000000000000015 126.0
HFD3_k127_1245546_11 PFAM UBA THIF-type NAD FAD binding protein K21029,K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000006013 121.0
HFD3_k127_1245546_12 Methyltransferase domain - - - 0.0000000000000000000000000002622 123.0
HFD3_k127_1245546_13 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000003006 91.0
HFD3_k127_1245546_14 Pkd domain containing protein - - - 0.0000000000114 70.0
HFD3_k127_1245546_15 Protein conserved in bacteria K09986 - - 0.00000000002676 74.0
HFD3_k127_1245546_2 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 372.0
HFD3_k127_1245546_3 domain protein K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 338.0
HFD3_k127_1245546_4 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 - 2.1.1.219,2.1.1.220 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 311.0
HFD3_k127_1245546_5 Major Facilitator Superfamily K08223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 302.0
HFD3_k127_1245546_6 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000001441 250.0
HFD3_k127_1245546_7 serine-type endopeptidase activity K04691,K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000002308 212.0
HFD3_k127_1245546_8 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.00000000000000000000000000000000000000007741 152.0
HFD3_k127_1245546_9 dTDP-4-dehydrorhamnose 3,5-epimerase activity K01790 - 5.1.3.13 0.000000000000000000000000000000000000002044 165.0
HFD3_k127_1275953_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 1.323e-226 742.0
HFD3_k127_1275953_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 402.0
HFD3_k127_1275953_2 Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005248 367.0
HFD3_k127_1275953_3 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 338.0
HFD3_k127_1275953_4 PFAM Coenzyme A transferase K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003557 297.0
HFD3_k127_1275953_5 Belongs to the UPF0271 (lamB) family K07160 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006245 269.0
HFD3_k127_1275953_6 CO dehydrogenase flavoprotein domain protein K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000009727 175.0
HFD3_k127_1275953_7 PFAM Bacterial regulatory proteins, gntR family - - - 0.0000000000000000000000000003871 123.0
HFD3_k127_1291902_0 Peptidoglycan-binding domain 1 protein K02450 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 - 2.218e-216 686.0
HFD3_k127_1291902_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 599.0
HFD3_k127_1291902_10 N-terminal TM domain of oligopeptide transport permease C K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 405.0
HFD3_k127_1291902_11 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007601 388.0
HFD3_k127_1291902_12 Domain of unknown function (DUF1731) K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 345.0
HFD3_k127_1291902_13 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 327.0
HFD3_k127_1291902_14 Poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 326.0
HFD3_k127_1291902_15 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 329.0
HFD3_k127_1291902_16 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 310.0
HFD3_k127_1291902_17 PFAM binding-protein-dependent transport systems inner membrane component K02033,K15581 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 298.0
HFD3_k127_1291902_18 LAO AO transport system K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 299.0
HFD3_k127_1291902_19 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 288.0
HFD3_k127_1291902_2 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 GO:0003674,GO:0003824,GO:0004321,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009268,GO:0009628,GO:0010447,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051704,GO:0071944 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 603.0
HFD3_k127_1291902_20 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001326 285.0
HFD3_k127_1291902_21 Alanine-glyoxylate amino-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004071 289.0
HFD3_k127_1291902_22 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004983 285.0
HFD3_k127_1291902_23 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002301 256.0
HFD3_k127_1291902_24 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000005889 240.0
HFD3_k127_1291902_25 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.0000000000000000000000000000000000000000000000000000000000000000006567 236.0
HFD3_k127_1291902_26 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000003716 234.0
HFD3_k127_1291902_27 Glucose dehydrogenase C-terminus K00008,K00060 - 1.1.1.103,1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000006389 235.0
HFD3_k127_1291902_28 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000004845 223.0
HFD3_k127_1291902_29 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000003496 233.0
HFD3_k127_1291902_3 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 597.0
HFD3_k127_1291902_30 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000001399 237.0
HFD3_k127_1291902_31 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000001454 226.0
HFD3_k127_1291902_32 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000001684 227.0
HFD3_k127_1291902_33 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000001774 191.0
HFD3_k127_1291902_34 response to pH - - - 0.0000000000000000000000000000000000000000000000000716 183.0
HFD3_k127_1291902_35 NAD dependent epimerase/dehydratase family K00023,K00059 - 1.1.1.100,1.1.1.36 0.0000000000000000000000000000000000000000000000001338 181.0
HFD3_k127_1291902_36 Fumarylacetoacetate (FAA) hydrolase family K02554 - 4.2.1.80 0.00000000000000000000000000000000000000000000001545 181.0
HFD3_k127_1291902_37 membrane - - - 0.0000000000000000000000000000000000000000000000282 186.0
HFD3_k127_1291902_38 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000001083 186.0
HFD3_k127_1291902_39 dehydratase - - - 0.000000000000000000000000000000000000000000001327 178.0
HFD3_k127_1291902_4 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005117 505.0
HFD3_k127_1291902_40 YsiA-like protein, C-terminal region K13770 - - 0.000000000000000000000000000000000000000000001512 172.0
HFD3_k127_1291902_41 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000004513 164.0
HFD3_k127_1291902_42 Glycoprotease family K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.00000000000000000000000000000000000001489 153.0
HFD3_k127_1291902_43 NUDIX domain - - - 0.000000000000000000000000000000001224 137.0
HFD3_k127_1291902_44 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000000000000000000000000229 140.0
HFD3_k127_1291902_45 PFAM MaoC domain protein dehydratase K17865 - 4.2.1.55 0.0000000000000000000000000000000109 141.0
HFD3_k127_1291902_46 EamA-like transporter family - - - 0.00000000000000000000000000000001224 138.0
HFD3_k127_1291902_47 PFAM MaoC like domain - - - 0.00000000000000000000000000000002518 147.0
HFD3_k127_1291902_48 Smr domain - - - 0.000000000000000000000000002368 126.0
HFD3_k127_1291902_49 PFAM PHA accumulation regulator DNA-binding protein - - - 0.0000000000000000000000004197 110.0
HFD3_k127_1291902_5 PFAM extracellular solute-binding protein family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009394 514.0
HFD3_k127_1291902_50 SnoaL-like domain - - - 0.00000000000000000000001143 105.0
HFD3_k127_1291902_51 membrane K02451,K03832 - - 0.00000000000000000000002057 112.0
HFD3_k127_1291902_52 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000003485 97.0
HFD3_k127_1291902_53 Thioredoxin-like - - - 0.000000000000003353 79.0
HFD3_k127_1291902_54 Protein of unknown function (DUF1232) - - - 0.00000000003658 77.0
HFD3_k127_1291902_55 polyhydroxyalkanoic acid synthase, PhaR subunit - - - 0.0000000002737 73.0
HFD3_k127_1291902_56 Redoxin K03564 - 1.11.1.15 0.000000001809 63.0
HFD3_k127_1291902_57 reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000001396 65.0
HFD3_k127_1291902_58 - - - - 0.00001333 56.0
HFD3_k127_1291902_59 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0001228 47.0
HFD3_k127_1291902_6 Domain of unknown function (DUF4445) K04755,K08952,K08953,K08954 GO:0005575,GO:0005622,GO:0005623,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0046858 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007182 506.0
HFD3_k127_1291902_60 Redoxin domain protein - - - 0.0008715 51.0
HFD3_k127_1291902_7 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 467.0
HFD3_k127_1291902_8 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004725 487.0
HFD3_k127_1291902_9 PFAM Alcohol dehydrogenase K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 413.0
HFD3_k127_1344398_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 412.0
HFD3_k127_1344398_1 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 338.0
HFD3_k127_1344398_2 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 295.0
HFD3_k127_1344398_3 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000001133 221.0
HFD3_k127_1344398_4 Acyl-CoA synthetase K00666 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051087 - 0.000000000000000000000000000000000000000000001608 166.0
HFD3_k127_1344398_5 - - - - 0.0000000001518 70.0
HFD3_k127_1344398_6 COG1413 FOG HEAT repeat K22221 - - 0.00000001903 67.0
HFD3_k127_1357054_0 Molydopterin dinucleotide binding domain K07306,K07309,K07310,K08352 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009390,GO:0009897,GO:0009986,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0032991,GO:0033797,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071944,GO:0098552,GO:0098567,GO:1902494 1.8.5.3,1.8.5.5,1.97.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009435 567.0
HFD3_k127_1357054_1 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 465.0
HFD3_k127_1357054_10 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000005342 200.0
HFD3_k127_1357054_11 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000221 175.0
HFD3_k127_1357054_12 short-chain dehydrogenase K07535,K10620 - 1.3.1.58 0.0000000000000000000000000000000000000000000002382 182.0
HFD3_k127_1357054_13 Creatinase/Prolidase N-terminal domain - - - 0.0000000000000000000000000000000000003473 156.0
HFD3_k127_1357054_14 Mo-molybdopterin cofactor metabolic process - - - 0.000000000000000003513 86.0
HFD3_k127_1357054_15 Unextendable partial coding region - - - 0.0000000000000001001 82.0
HFD3_k127_1357054_16 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000000000007201 79.0
HFD3_k127_1357054_17 Aminoglycoside phosphotransferase - - - 0.0000000000004154 76.0
HFD3_k127_1357054_2 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004929 422.0
HFD3_k127_1357054_3 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 381.0
HFD3_k127_1357054_4 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000002045 273.0
HFD3_k127_1357054_5 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006311 257.0
HFD3_k127_1357054_6 Lytic transglycosylase, SLT, LysM and LysM domain-containing K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000002857 249.0
HFD3_k127_1357054_7 Protein of unknown function DUF47 K02039,K07220 - - 0.00000000000000000000000000000000000000000000000000000000000003604 221.0
HFD3_k127_1357054_8 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000003427 211.0
HFD3_k127_1357054_9 PFAM peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000475 185.0
HFD3_k127_1398259_0 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 473.0
HFD3_k127_1398259_1 alcohol dehydrogenase (NAD) activity K00001,K00121,K02267,K13980,K18857 GO:0000302,GO:0001101,GO:0001666,GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006970,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009410,GO:0009413,GO:0009414,GO:0009415,GO:0009628,GO:0009636,GO:0009651,GO:0009719,GO:0009725,GO:0009737,GO:0009743,GO:0009744,GO:0010033,GO:0010035,GO:0010038,GO:0010243,GO:0014070,GO:0014074,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0031000,GO:0032355,GO:0033993,GO:0034285,GO:0036270,GO:0036293,GO:0042221,GO:0042493,GO:0042542,GO:0042802,GO:0042803,GO:0043279,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046686,GO:0046983,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0055114,GO:0065007,GO:0070482,GO:0071944,GO:0080134,GO:0080135,GO:0097305,GO:1900037,GO:1900039,GO:1901698,GO:1901700 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 438.0
HFD3_k127_1398259_2 Aminotransferase class-III K00822,K00833 - 2.6.1.18,2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007941 418.0
HFD3_k127_1398259_3 Encapsulating protein for peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004953 250.0
HFD3_k127_1398259_4 Asp/Glu/Hydantoin racemase K16841 - 5.1.99.3 0.00000000000000000000002645 111.0
HFD3_k127_141745_0 PFAM Mandelate racemase muconate lactonizing K20023 - 4.2.1.156,4.2.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 537.0
HFD3_k127_141745_1 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 495.0
HFD3_k127_141745_2 COG0444 ABC-type dipeptide oligopeptide nickel transport system, ATPase component K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 455.0
HFD3_k127_141745_3 conserved protein (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009914 387.0
HFD3_k127_141745_4 Threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 380.0
HFD3_k127_141745_5 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002382 283.0
HFD3_k127_141745_6 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000474 141.0
HFD3_k127_1513181_0 Two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 509.0
HFD3_k127_1513181_1 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000003133 192.0
HFD3_k127_1513181_2 PFAM UspA domain protein - - - 0.00000000000000000000002812 108.0
HFD3_k127_1513181_3 Universal stress protein - - - 0.00000000000000005529 86.0
HFD3_k127_1513181_4 Protein of unknown function (DUF2892) - - - 0.000001644 60.0
HFD3_k127_1573014_0 Heat shock 70 kDa protein K04043 - - 1.147e-288 899.0
HFD3_k127_1573014_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.744e-276 881.0
HFD3_k127_1573014_10 PFAM Lytic transglycosylase catalytic K08309 - - 0.0000000000000000000000000000000000000000002171 168.0
HFD3_k127_1573014_11 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000001377 130.0
HFD3_k127_1573014_12 helix_turn_helix, mercury resistance K13640 - - 0.00000000000000000000006991 113.0
HFD3_k127_1573014_13 phosphorelay signal transduction system K02667 - - 0.000000000000000000003494 99.0
HFD3_k127_1573014_14 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000007774 85.0
HFD3_k127_1573014_15 Domain of unknown function (DUF1844) - - - 0.000000002234 66.0
HFD3_k127_1573014_2 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 532.0
HFD3_k127_1573014_3 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 472.0
HFD3_k127_1573014_4 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 456.0
HFD3_k127_1573014_5 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000008747 275.0
HFD3_k127_1573014_6 MazG nucleotide pyrophosphohydrolase domain K02428,K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66,3.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000002583 268.0
HFD3_k127_1573014_7 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000003114 244.0
HFD3_k127_1573014_8 PFAM formyl transferase domain protein K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000217 229.0
HFD3_k127_1573014_9 PFAM GDSL-like Lipase Acylhydrolase - - - 0.0000000000000000000000000000000000000000001932 165.0
HFD3_k127_1574652_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 1.511e-210 661.0
HFD3_k127_1574652_1 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006981 593.0
HFD3_k127_1574652_10 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 321.0
HFD3_k127_1574652_11 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007757 276.0
HFD3_k127_1574652_12 Caspase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003111 264.0
HFD3_k127_1574652_13 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000009633 277.0
HFD3_k127_1574652_14 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000003606 233.0
HFD3_k127_1574652_15 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000001064 227.0
HFD3_k127_1574652_16 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000005334 205.0
HFD3_k127_1574652_17 Secretin and TonB N terminus short domain K02666 - - 0.00000000000000000000000000000000000000000000000007046 199.0
HFD3_k127_1574652_18 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000001806 193.0
HFD3_k127_1574652_19 Mechanosensitive ion channel K22044 - - 0.000000000000000000000000000000000000000000000001796 197.0
HFD3_k127_1574652_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007501 543.0
HFD3_k127_1574652_20 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000003683 182.0
HFD3_k127_1574652_21 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000002417 169.0
HFD3_k127_1574652_22 PAS domain K02668,K07708,K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000137 175.0
HFD3_k127_1574652_23 Diguanylate cyclase K02488 - 2.7.7.65 0.0000000000000000000000000000000000001539 158.0
HFD3_k127_1574652_24 IclR helix-turn-helix domain K10439 - - 0.000000000000000000000000000000000365 145.0
HFD3_k127_1574652_25 PFAM transport-associated - - - 0.000000000000000000000000000001621 133.0
HFD3_k127_1574652_26 Arabinose efflux permease family protein - - - 0.000000000000000000000001339 118.0
HFD3_k127_1574652_27 response regulator - - - 0.0000000000000000000000196 104.0
HFD3_k127_1574652_28 ATP-binding region, ATPase domain protein - - - 0.0000000000000000000001743 106.0
HFD3_k127_1574652_29 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000005502 95.0
HFD3_k127_1574652_3 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 475.0
HFD3_k127_1574652_30 Prokaryotic N-terminal methylation motif K02650 - - 0.00000001223 65.0
HFD3_k127_1574652_32 Cytochrome C' - - - 0.00003679 52.0
HFD3_k127_1574652_33 TIGRFAM regulatory protein, FmdB family - - - 0.0004679 46.0
HFD3_k127_1574652_4 PFAM Type II secretion system protein E K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 489.0
HFD3_k127_1574652_5 Beta-eliminating lyase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 430.0
HFD3_k127_1574652_6 Two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 424.0
HFD3_k127_1574652_7 Utp--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006028 374.0
HFD3_k127_1574652_8 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 341.0
HFD3_k127_1574652_9 PFAM peptidase S1 and S6, chymotrypsin Hap K04771,K04772 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006247 355.0
HFD3_k127_1578366_0 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000272 276.0
HFD3_k127_1578366_1 thiolester hydrolase activity K17362 - - 0.000000000000000000000000000000000000001371 151.0
HFD3_k127_1578366_2 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 0.000000000000000000000000000003289 136.0
HFD3_k127_1578366_3 BetI-type transcriptional repressor, C-terminal - - - 0.00000000000000000003869 98.0
HFD3_k127_1578366_4 PFAM Acetyltransferase (GNAT) family K03828,K03829 - - 0.000000000000002595 83.0
HFD3_k127_1578366_5 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.00000000009996 62.0
HFD3_k127_1584745_0 UvrD/REP helicase N-terminal domain - - - 5.849e-317 1024.0
HFD3_k127_1584745_1 Penicillin amidase K01434 - 3.5.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000371 596.0
HFD3_k127_1584745_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005786 305.0
HFD3_k127_1584745_3 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000004351 248.0
HFD3_k127_1584745_4 PD-(D/E)XK nuclease superfamily - - - 0.00000000000005279 84.0
HFD3_k127_1595786_0 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 561.0
HFD3_k127_1595786_1 metal-dependent hydrolase of the TIM-barrel fold K07046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007467 326.0
HFD3_k127_1595786_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000005325 188.0
HFD3_k127_1595786_3 - - - - 0.0000000000000000000000000000000000000000000002872 179.0
HFD3_k127_1595786_4 COG2346, Truncated hemoglobins K06886 - - 0.00000000000000000000000000000000000000000008598 167.0
HFD3_k127_1595786_5 Belongs to the urease gamma subunit family K01430 - 3.5.1.5 0.000000000000000000000000003004 120.0
HFD3_k127_1595786_6 Urease, gamma subunit K14048 - 3.5.1.5 0.000000000000000000000185 106.0
HFD3_k127_160099_0 Amidase K01426 - 3.5.1.4 1.383e-236 740.0
HFD3_k127_160099_1 Periplasmic binding protein domain K11959 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 576.0
HFD3_k127_160099_10 Nacht domain - - - 0.000000000004667 70.0
HFD3_k127_160099_2 Belongs to the binding-protein-dependent transport system permease family K01997,K11960 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 383.0
HFD3_k127_160099_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 377.0
HFD3_k127_160099_4 ATPases associated with a variety of cellular activities K01995,K11962 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 338.0
HFD3_k127_160099_5 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 329.0
HFD3_k127_160099_6 ATPases associated with a variety of cellular activities K01996,K11963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007479 291.0
HFD3_k127_160099_7 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008178 264.0
HFD3_k127_160099_8 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000002846 231.0
HFD3_k127_160099_9 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000002753 95.0
HFD3_k127_1637177_0 Glycosyl transferases group 1 K19424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 470.0
HFD3_k127_1637177_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000006805 244.0
HFD3_k127_1637177_2 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000004888 228.0
HFD3_k127_1637177_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000001873 222.0
HFD3_k127_1637177_4 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000000006087 220.0
HFD3_k127_1637177_5 O-Antigen Polymerase K02847 - - 0.0000000000000000000000000000000347 145.0
HFD3_k127_1644292_0 Squalene-hopene cyclase C-terminal domain K06045 - 4.2.1.129,5.4.99.17 7.429e-210 670.0
HFD3_k127_1644292_1 Myo-inositol-1-phosphate synthase, GAPDH domain protein K01858 - 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 523.0
HFD3_k127_1644292_10 Carotenoid biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000007873 213.0
HFD3_k127_1644292_11 intermembrane phospholipid transfer K07323 - - 0.0000000000000000000000000000000000000000000000000003695 192.0
HFD3_k127_1644292_12 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000000000000000000001924 192.0
HFD3_k127_1644292_13 MlaD protein K02067 - - 0.00000000000000000000000000000000000000009078 161.0
HFD3_k127_1644292_14 - - - - 0.0000000000000000000009234 99.0
HFD3_k127_1644292_15 Phosphorylase superfamily K01243 - 3.2.2.9 0.000000000000002058 87.0
HFD3_k127_1644292_16 Lipid A 3-O-deacylase (PagL) - - - 0.0000001365 64.0
HFD3_k127_1644292_2 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008152 516.0
HFD3_k127_1644292_3 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 391.0
HFD3_k127_1644292_4 NmrA-like family K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009644 381.0
HFD3_k127_1644292_5 elongation factor Tu domain 2 protein K02355 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005625 362.0
HFD3_k127_1644292_6 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 315.0
HFD3_k127_1644292_7 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001348 303.0
HFD3_k127_1644292_8 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001468 275.0
HFD3_k127_1644292_9 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000003017 264.0
HFD3_k127_1666009_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006335 470.0
HFD3_k127_1666009_1 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009604 332.0
HFD3_k127_1666009_2 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005518 323.0
HFD3_k127_1666009_3 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009216 306.0
HFD3_k127_1666009_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009976 308.0
HFD3_k127_1666009_5 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001607 273.0
HFD3_k127_1666009_6 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000001179 236.0
HFD3_k127_1666009_7 Amidohydrolase - - - 0.00000000000000000000000000000000003495 149.0
HFD3_k127_1666009_8 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000008944 105.0
HFD3_k127_1668939_0 zinc ion binding K07048 GO:0008150,GO:0009888,GO:0009987,GO:0030154,GO:0030855,GO:0032502,GO:0048856,GO:0048869,GO:0060429 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 305.0
HFD3_k127_1668939_1 YD repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 322.0
HFD3_k127_1668939_2 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003484 245.0
HFD3_k127_1668939_3 Protein of unknown function (DUF3494) - - - 0.00000001227 70.0
HFD3_k127_16889_0 ABC transporter K02471 - - 4.6e-294 911.0
HFD3_k127_16889_1 Dehydrogenase E1 component K00164 - 1.2.4.2 6.077e-273 894.0
HFD3_k127_16889_2 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 532.0
HFD3_k127_16889_3 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009959 426.0
HFD3_k127_16889_4 PFAM SMP-30 Gluconolaconase LRE domain protein K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 321.0
HFD3_k127_16889_5 unfolded protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000002356 242.0
HFD3_k127_16889_6 Protein of unknown function (DUF1326) - - - 0.0000000000000000000000000000000000000000000000000000000000002433 218.0
HFD3_k127_16889_7 SET domain K07117 - - 0.00000000000000000000000000000000000000000000000003499 186.0
HFD3_k127_16889_8 metal-binding integral membrane protein - - - 0.00000000000000000000000000000000000000000003523 171.0
HFD3_k127_16889_9 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - GO:0000166,GO:0000959,GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003723,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006970,GO:0007275,GO:0008144,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009414,GO:0009415,GO:0009451,GO:0009628,GO:0009631,GO:0009651,GO:0009791,GO:0009845,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010035,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031554,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0034336,GO:0034641,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043242,GO:0043244,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0060567,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090351,GO:0097159,GO:0097367,GO:1900864,GO:1901265,GO:1901360,GO:1901363,GO:1901700,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000128 99.0
HFD3_k127_1689215_0 cob(I)yrinic acid a,c-diamide adenosyltransferase activity K00798,K13821 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.2.1.88,1.5.5.2,2.5.1.17 0.00000000000000000000000000000000000000000000000000000000001749 212.0
HFD3_k127_1689215_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000015 204.0
HFD3_k127_1689215_2 CoA binding domain K06929 - - 0.00000000000000000000000000000000000000000000000000003222 190.0
HFD3_k127_1689215_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000005414 95.0
HFD3_k127_1706002_0 AMP-binding enzyme C-terminal domain K00666 - - 1.194e-275 854.0
HFD3_k127_1706002_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 513.0
HFD3_k127_1706002_10 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008301 330.0
HFD3_k127_1706002_11 PFAM response regulator receiver K07665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 291.0
HFD3_k127_1706002_12 Alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 289.0
HFD3_k127_1706002_13 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004441 278.0
HFD3_k127_1706002_14 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000003499 276.0
HFD3_k127_1706002_15 myo-inosose-2 dehydratase activity K00457,K06606 - 1.13.11.27,5.3.99.11 0.0000000000000000000000000000000000000000000000000000000000000007215 241.0
HFD3_k127_1706002_16 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K04756 - - 0.0000000000000000000000000000000000000000000000000000000000001018 227.0
HFD3_k127_1706002_17 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.00000000000000000000000000000000000000000000000009097 194.0
HFD3_k127_1706002_18 Glcg protein - - - 0.0000000000000000000000000000000000000000003794 166.0
HFD3_k127_1706002_2 Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities K00842,K14155 - 4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000039 456.0
HFD3_k127_1706002_20 deoxyhypusine monooxygenase activity K05384,K05386 - - 0.0000000000000000000000000000008382 128.0
HFD3_k127_1706002_21 Pfam:DUF385 - - - 0.000000000000000004172 93.0
HFD3_k127_1706002_22 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000001304 79.0
HFD3_k127_1706002_23 - - - - 0.000000000101 66.0
HFD3_k127_1706002_3 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 461.0
HFD3_k127_1706002_4 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 425.0
HFD3_k127_1706002_5 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008862 407.0
HFD3_k127_1706002_6 Methionine synthase K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000995 387.0
HFD3_k127_1706002_7 PFAM Rhodanese domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 376.0
HFD3_k127_1706002_8 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 355.0
HFD3_k127_1706002_9 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07644 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 346.0
HFD3_k127_1706214_0 FAD linked oxidases, C-terminal domain - - - 2.852e-308 971.0
HFD3_k127_1706214_1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain K01596,K01610 - 4.1.1.32,4.1.1.49 3.905e-258 806.0
HFD3_k127_1706214_10 PFAM sigma-54 factor interaction domain-containing protein K02481,K07714,K10943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 378.0
HFD3_k127_1706214_11 Universal stress protein UspA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 289.0
HFD3_k127_1706214_12 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000003502 245.0
HFD3_k127_1706214_13 NAD binding K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000001187 259.0
HFD3_k127_1706214_14 Aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000001662 234.0
HFD3_k127_1706214_15 Belongs to the BI1 family K06890 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000006727 220.0
HFD3_k127_1706214_16 ABC transporter K02049 - - 0.00000000000000000000000000000000000000000000000000000000005857 223.0
HFD3_k127_1706214_17 PFAM ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000001528 214.0
HFD3_k127_1706214_18 thiamine-containing compound biosynthetic process K02051,K15553 - - 0.0000000000000000000000000000000000000000000000000000003495 205.0
HFD3_k127_1706214_19 PFAM YdjC family protein K03478 - 3.5.1.105 0.000000000000000000000000000000000000000000000003723 186.0
HFD3_k127_1706214_2 helicase superfamily c-terminal domain K03727 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 6.186e-231 742.0
HFD3_k127_1706214_20 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000004896 168.0
HFD3_k127_1706214_21 Lipid A Biosynthesis N-terminal domain - - - 0.00000000000000000000000000000000001252 138.0
HFD3_k127_1706214_22 Thioredoxin-like - - - 0.0000000000000000004868 94.0
HFD3_k127_1706214_23 Dehydrogenase K00121,K00148 - 1.1.1.1,1.1.1.284,1.2.1.46 0.000000000000004717 78.0
HFD3_k127_1706214_24 Mo-molybdopterin cofactor metabolic process - - - 0.00001605 57.0
HFD3_k127_1706214_3 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 3.043e-214 673.0
HFD3_k127_1706214_4 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 544.0
HFD3_k127_1706214_5 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006968 509.0
HFD3_k127_1706214_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007096 509.0
HFD3_k127_1706214_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 473.0
HFD3_k127_1706214_8 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 435.0
HFD3_k127_1706214_9 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 366.0
HFD3_k127_1725158_0 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 3.815e-225 722.0
HFD3_k127_1725158_1 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 1.949e-222 703.0
HFD3_k127_1725158_2 Luciferase-like monooxygenase - - - 1.613e-212 666.0
HFD3_k127_1725158_3 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 521.0
HFD3_k127_1725158_4 Belongs to the MurCDEF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008116 293.0
HFD3_k127_1725158_5 Oxidoreductase - - - 0.00000000000000000000000000000000000000000000003238 183.0
HFD3_k127_1732148_0 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 3.787e-269 844.0
HFD3_k127_1732148_1 Periplasmic binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 548.0
HFD3_k127_1732148_10 ABC transporter - - - 0.00000000000000000000569 92.0
HFD3_k127_1732148_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 547.0
HFD3_k127_1732148_3 Belongs to the binding-protein-dependent transport system permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 514.0
HFD3_k127_1732148_4 leucyl aminopeptidase, aminopeptidase T K18028 - 1.13.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 488.0
HFD3_k127_1732148_5 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007201 490.0
HFD3_k127_1732148_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 417.0
HFD3_k127_1732148_7 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 380.0
HFD3_k127_1732148_8 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 396.0
HFD3_k127_1732148_9 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000007599 272.0
HFD3_k127_1734504_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1323.0
HFD3_k127_1734504_1 Aldehyde oxidase and xanthine dehydrogenase a b hammerhead K03520,K11177 - 1.17.1.4,1.2.5.3 0.0 1315.0
HFD3_k127_1734504_10 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 310.0
HFD3_k127_1734504_11 YHS domain K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009632 261.0
HFD3_k127_1734504_12 COGs COG2080 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS CutS homologs K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000001079 243.0
HFD3_k127_1734504_13 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000005584 228.0
HFD3_k127_1734504_14 NMT1/THI5 like K02051 - - 0.00000000000000000000000000000000000000000000000000000000001469 220.0
HFD3_k127_1734504_15 - - - - 0.0000000000000000000000000000000000000000000000000000000002696 218.0
HFD3_k127_1734504_16 membrane - - - 0.0000000000000000000000000000000000000000000000000000004042 199.0
HFD3_k127_1734504_17 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000007157 77.0
HFD3_k127_1734504_18 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000193 72.0
HFD3_k127_1734504_19 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000003237 61.0
HFD3_k127_1734504_2 Histidine kinase-like ATPases - - - 9.519e-244 807.0
HFD3_k127_1734504_20 Tripartite tricarboxylate transporter TctB family - - - 0.000000002074 66.0
HFD3_k127_1734504_22 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000003531 54.0
HFD3_k127_1734504_23 PFAM extracellular solute-binding protein family 5 K02035 - - 0.000006007 51.0
HFD3_k127_1734504_24 - - - - 0.000008726 53.0
HFD3_k127_1734504_25 Belongs to the 'phage' integrase family - - - 0.00006465 48.0
HFD3_k127_1734504_26 PFAM Acetyltransferase (GNAT) family - - - 0.00007271 55.0
HFD3_k127_1734504_3 PFAM Tripartite tricarboxylate transporter TctA family K07793 - - 3.593e-201 637.0
HFD3_k127_1734504_4 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008828 382.0
HFD3_k127_1734504_5 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 383.0
HFD3_k127_1734504_6 Aminotransferase K11358 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 396.0
HFD3_k127_1734504_7 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 340.0
HFD3_k127_1734504_8 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 338.0
HFD3_k127_1734504_9 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009925 318.0
HFD3_k127_1734818_0 Heavy-metal-associated domain K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 630.0
HFD3_k127_1734818_1 methyltransferase - - - 0.000000000000000000000000000002643 130.0
HFD3_k127_1734818_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000001618 115.0
HFD3_k127_1734818_3 TIGRFAM Protein of - - - 0.0000000000000003111 81.0
HFD3_k127_1734818_4 Uncharacterized ACR, COG1993 K09137 - - 0.000003657 55.0
HFD3_k127_1761704_0 MotA/TolQ/ExbB proton channel family K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 302.0
HFD3_k127_1761704_1 Biopolymer transport protein ExbD/TolR K03559 - - 0.0000000000000000000000000000004103 126.0
HFD3_k127_1761704_2 Biopolymer transport protein ExbD/TolR K03560 - - 0.00000000000000000000008975 104.0
HFD3_k127_1761704_3 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000007932 56.0
HFD3_k127_1809145_0 argininosuccinate lyase K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006335 520.0
HFD3_k127_1809145_1 Bacterial sugar transferase K03606,K20997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 492.0
HFD3_k127_1809145_10 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000009714 135.0
HFD3_k127_1809145_11 O-antigen ligase like membrane protein - - - 0.000000000000000000000006795 115.0
HFD3_k127_1809145_12 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000001725 102.0
HFD3_k127_1809145_2 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004449 432.0
HFD3_k127_1809145_3 Polysaccharide biosynthesis protein K15856 - 1.1.1.281 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 398.0
HFD3_k127_1809145_4 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 364.0
HFD3_k127_1809145_5 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000425 305.0
HFD3_k127_1809145_6 fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005303 294.0
HFD3_k127_1809145_7 Fibronectin type 3 domain - - - 0.000000000000000000000000000000003674 149.0
HFD3_k127_1809145_8 Sigma-70, region 4 K03088 GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000002015 136.0
HFD3_k127_1809145_9 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950,K13940 - 2.7.6.3,4.1.2.25 0.00000000000000000000000000000002739 132.0
HFD3_k127_1835316_0 Molydopterin dinucleotide binding domain K00123,K05299 - 1.17.1.10,1.17.1.9 0.0 1329.0
HFD3_k127_1835316_1 PFAM formate-tetrahydrofolate ligase FTHFS K01938 - 6.3.4.3 5.544e-240 764.0
HFD3_k127_1835316_10 TIGRFAM Threonine synthase - - - 0.0000005188 54.0
HFD3_k127_1835316_2 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00239,K00244 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009282 597.0
HFD3_k127_1835316_3 NADH dehydrogenase K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 394.0
HFD3_k127_1835316_4 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K03438,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009249,GO:0009898,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 327.0
HFD3_k127_1835316_5 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000007949 193.0
HFD3_k127_1835316_7 Formiminotransferase-cyclodeaminase - - - 0.00000000001936 72.0
HFD3_k127_1835316_8 Redoxin domain protein - - - 0.00000000002167 68.0
HFD3_k127_1835316_9 Thioredoxin-like K02199 - - 0.00000001724 59.0
HFD3_k127_184209_0 COG1228 Imidazolonepropionase and related amidohydrolases - - - 8.613e-199 626.0
HFD3_k127_184209_1 ATPase associated with various cellular K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009503 356.0
HFD3_k127_184209_10 Helix-hairpin-helix motif - - - 0.0000000000000000000002344 101.0
HFD3_k127_184209_11 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000002849 84.0
HFD3_k127_184209_12 Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000003006 81.0
HFD3_k127_184209_13 CoA binding domain - - - 0.00000000005917 63.0
HFD3_k127_184209_2 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway K03707 - 3.5.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 299.0
HFD3_k127_184209_3 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007739 264.0
HFD3_k127_184209_4 Domain of unknown function (DUF3488) - - - 0.000000000000000000000000000000000000000000000000000000000000001876 243.0
HFD3_k127_184209_5 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.0000000000000000000000000000000000000000000000000000000000001034 233.0
HFD3_k127_184209_6 Proteasomal ATPase OB/ID domain K07184,K07777,K12065,K13525,K13527 GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000003319 217.0
HFD3_k127_184209_7 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000991 180.0
HFD3_k127_184209_8 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000002087 151.0
HFD3_k127_184209_9 F420-dependent oxidoreductase - - - 0.0000000000000000000000009509 109.0
HFD3_k127_1849961_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 449.0
HFD3_k127_1849961_1 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000004679 209.0
HFD3_k127_1849961_2 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000001867 185.0
HFD3_k127_1849961_3 Antibiotic biosynthesis monooxygenase K11530 - 5.3.1.32 0.0000000000000000000005569 99.0
HFD3_k127_1887037_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0 1097.0
HFD3_k127_1887037_1 Aconitase C-terminal domain K01681 - 4.2.1.3 5.133e-209 685.0
HFD3_k127_1887037_10 PFAM Short-chain dehydrogenase reductase SDR - - - 0.00000000000000001075 96.0
HFD3_k127_1887037_11 His Kinase A (phosphoacceptor) domain - - - 0.000000000004296 77.0
HFD3_k127_1887037_2 protoporphyrinogen oxidase activity K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 451.0
HFD3_k127_1887037_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K01719,K13542 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,4.1.1.37,4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 434.0
HFD3_k127_1887037_4 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006394 386.0
HFD3_k127_1887037_5 Acyl-CoA dehydrogenase, C-terminal domain K11731 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 383.0
HFD3_k127_1887037_6 PrpF protein K09788 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 372.0
HFD3_k127_1887037_7 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001631 292.0
HFD3_k127_1887037_8 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000006336 158.0
HFD3_k127_1887037_9 Belongs to the enoyl-CoA hydratase isomerase family K01692,K15866 - 4.2.1.17,5.3.3.18 0.000000000000000000000000000000008612 146.0
HFD3_k127_1887129_0 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 505.0
HFD3_k127_1887129_1 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005446 390.0
HFD3_k127_1887129_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000009935 222.0
HFD3_k127_1887129_3 dihydroorotate dehydrogenase activity K02823,K17828 - 1.3.1.14 0.000000000000000000000000000000000000000000000000000000001402 217.0
HFD3_k127_1887129_4 DNA helicase - - - 0.00000000000000000000000000000000000000009535 165.0
HFD3_k127_1887129_5 Protein of unknown function (DUF2892) - - - 0.00000000000000000000000000000000000004226 150.0
HFD3_k127_1887129_6 - - - - 0.00000000000000000000000000000005347 129.0
HFD3_k127_1887129_7 Mandelate Racemase Muconate Lactonizing - - - 0.0003158 49.0
HFD3_k127_1887397_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - 1.701e-253 791.0
HFD3_k127_1887397_1 ABC transporter K06022,K06158,K10834 - 3.6.3.29,3.6.3.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003295 561.0
HFD3_k127_1887397_10 Single-strand binding protein family K03111 - - 0.00000000000000000000000000000000000000007831 160.0
HFD3_k127_1887397_11 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.0000000000000000000000000000000000000001151 153.0
HFD3_k127_1887397_12 8-oxoguanine DNA glycosylase K01247 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003905,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008725,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0032131,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0043733,GO:0043916,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.21 0.0000000000000000000000000000000000004298 152.0
HFD3_k127_1887397_13 PFAM SNARE associated Golgi protein K03975,K19302 - 3.6.1.27 0.000000000000000000000000000000000181 140.0
HFD3_k127_1887397_14 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000009094 134.0
HFD3_k127_1887397_15 SMART HNH nuclease K07451 - - 0.0000000000000000000000000000004966 129.0
HFD3_k127_1887397_16 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000000000000000000003375 117.0
HFD3_k127_1887397_17 Cold shock protein K03704 - - 0.00000000000000000000000002375 111.0
HFD3_k127_1887397_18 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000006356 100.0
HFD3_k127_1887397_19 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071944,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000007532 91.0
HFD3_k127_1887397_2 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005316 498.0
HFD3_k127_1887397_20 COG1555 DNA uptake protein and related DNA-binding proteins K02237 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - 0.000000000001135 75.0
HFD3_k127_1887397_21 Protein of unknown function (DUF971) - - - 0.0002769 53.0
HFD3_k127_1887397_3 ATPases associated with a variety of cellular activities K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 407.0
HFD3_k127_1887397_4 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 381.0
HFD3_k127_1887397_5 AAA domain (Cdc48 subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 375.0
HFD3_k127_1887397_6 COG2513 PEP phosphonomutase and related enzymes K01637 GO:0003674,GO:0003824,GO:0004451,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046487,GO:0071704 4.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000517 328.0
HFD3_k127_1887397_7 Actin K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002461 255.0
HFD3_k127_1887397_8 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000001077 207.0
HFD3_k127_1887397_9 PFAM pyridoxamine 5'-phosphate oxidase-related - - - 0.00000000000000000000000000000000000000002379 156.0
HFD3_k127_1888977_0 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000007831 143.0
HFD3_k127_1888977_1 HEAT repeats - - - 0.00001592 56.0
HFD3_k127_1891050_0 Belongs to the peptidase S8 family - - - 0.0000000000000000000004468 106.0
HFD3_k127_1932407_0 56kDa selenium binding protein (SBP56) K17285 - - 2.211e-264 825.0
HFD3_k127_1932407_1 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 612.0
HFD3_k127_1932407_10 PFAM Chromate transporter K07240 - - 0.000000000000007659 81.0
HFD3_k127_1932407_11 Protein of unknown function (DUF1499) - - - 0.0000000000002614 74.0
HFD3_k127_1932407_12 acetyltransferase - - - 0.00002135 48.0
HFD3_k127_1932407_13 Protoglobin - - - 0.00005236 53.0
HFD3_k127_1932407_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 550.0
HFD3_k127_1932407_3 PFAM alanine racemase domain protein K20757 - 4.3.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004159 375.0
HFD3_k127_1932407_4 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 304.0
HFD3_k127_1932407_5 FMN-dependent dehydrogenase K16422 - 1.1.3.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000275 269.0
HFD3_k127_1932407_6 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002128 255.0
HFD3_k127_1932407_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000008315 237.0
HFD3_k127_1932407_8 PFAM Cupin 2 conserved barrel domain protein K21700 - - 0.00000000000000000000000000005773 135.0
HFD3_k127_1932407_9 Chromate transporter K07240 - - 0.00000000000000000000000003719 122.0
HFD3_k127_1937235_0 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000003077 222.0
HFD3_k127_1937235_1 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000544 153.0
HFD3_k127_1937235_2 - - - - 0.000000006498 63.0
HFD3_k127_1939868_0 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000615 504.0
HFD3_k127_1939868_1 PFAM peptidase S8 and S53 subtilisin kexin sedolisin K08651 - 3.4.21.66 0.00000000000000000000000000000000000000000000008124 191.0
HFD3_k127_1939868_2 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000000007163 117.0
HFD3_k127_1939868_3 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000001968 91.0
HFD3_k127_1939868_4 - - - - 0.0000000001746 64.0
HFD3_k127_194410_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 2.56e-247 781.0
HFD3_k127_194410_1 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003794 511.0
HFD3_k127_194410_2 PFAM glycosyl transferase group 1 K00754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 474.0
HFD3_k127_194410_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 347.0
HFD3_k127_194410_4 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 298.0
HFD3_k127_194410_5 MULE transposase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007564 271.0
HFD3_k127_194410_6 Belongs to the IlvD Edd family K22396 - 4.2.1.82 0.000000000000000000000000003401 113.0
HFD3_k127_194410_7 DinB family - - - 0.0000000000000000000005874 104.0
HFD3_k127_194410_8 DinB superfamily - - - 0.000000000000001054 84.0
HFD3_k127_1946353_0 B12 binding domain K00548 - 2.1.1.13 0.0 1424.0
HFD3_k127_1946353_1 Protein of unknown function, DUF255 K06888 - - 5.589e-242 780.0
HFD3_k127_1946353_10 racemase activity, acting on amino acids and derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000002821 247.0
HFD3_k127_1946353_11 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000005545 234.0
HFD3_k127_1946353_12 peptide deformylase activity K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000001066 226.0
HFD3_k127_1946353_13 Belongs to the Dps family K04047 - - 0.0000000000000000000000000000000000000000000000000000000006147 209.0
HFD3_k127_1946353_14 Thioesterase K07107 - - 0.0000000000000000000000000000000000000000000000000000004147 205.0
HFD3_k127_1946353_15 cytokinin biosynthetic process K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000001402 177.0
HFD3_k127_1946353_16 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000003775 177.0
HFD3_k127_1946353_18 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000282 125.0
HFD3_k127_1946353_19 Nitroreductase family - - - 0.0000000000000000000001271 104.0
HFD3_k127_1946353_2 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006384 564.0
HFD3_k127_1946353_20 DinB superfamily - - - 0.00000000000000001727 95.0
HFD3_k127_1946353_21 COG2104 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.000000000000614 72.0
HFD3_k127_1946353_22 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000001337 76.0
HFD3_k127_1946353_23 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0000001591 64.0
HFD3_k127_1946353_3 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 370.0
HFD3_k127_1946353_4 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 358.0
HFD3_k127_1946353_5 Binding-protein-dependent transport systems inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009574 283.0
HFD3_k127_1946353_6 FES K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002243 263.0
HFD3_k127_1946353_7 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000006438 257.0
HFD3_k127_1946353_8 PFAM Binding-protein-dependent transport system inner membrane component K02025,K15771 - - 0.000000000000000000000000000000000000000000000000000000000000000000003395 244.0
HFD3_k127_1946353_9 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000002798 244.0
HFD3_k127_1955842_0 High confidence in function and specificity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006164 341.0
HFD3_k127_1955842_1 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.000000000000000000000000000000000001547 142.0
HFD3_k127_1993099_0 Histidine kinase-like ATPases - - - 1.63e-321 1045.0
HFD3_k127_1993099_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01576,K01652 - 2.2.1.6,4.1.1.7 3.823e-214 680.0
HFD3_k127_1993099_2 Belongs to the ABC transporter superfamily K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008824 475.0
HFD3_k127_1993099_3 Taurine catabolism dioxygenase TauD, TfdA family K06912 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 463.0
HFD3_k127_1993099_4 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 430.0
HFD3_k127_1993099_5 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 387.0
HFD3_k127_1993099_6 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 366.0
HFD3_k127_1993099_7 Aldo/keto reductase family K18471 - - 0.0000000000000000000000000000000000000000000000000000000000000000006427 241.0
HFD3_k127_1993099_8 PFAM Deoxyhypusine synthase K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000004971 184.0
HFD3_k127_1993099_9 Luciferase-like monooxygenase - - - 0.0000000000000000001303 92.0
HFD3_k127_2034390_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.436e-292 910.0
HFD3_k127_206279_0 Belongs to the amidase family K01426 - 3.5.1.4 1.054e-250 782.0
HFD3_k127_206279_1 MacB-like periplasmic core domain K02004 - - 3.515e-242 788.0
HFD3_k127_206279_10 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 406.0
HFD3_k127_206279_11 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 406.0
HFD3_k127_206279_12 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006291 357.0
HFD3_k127_206279_13 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 373.0
HFD3_k127_206279_14 Isocitrate lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009195 353.0
HFD3_k127_206279_15 Branched-chain amino acid ATP-binding cassette transporter K01995,K11962 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003432 322.0
HFD3_k127_206279_16 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 302.0
HFD3_k127_206279_17 Phosphoenolpyruvate phosphomutase K03417 - 4.1.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 301.0
HFD3_k127_206279_18 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 304.0
HFD3_k127_206279_19 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007153 279.0
HFD3_k127_206279_2 SMART alpha amylase, catalytic sub domain K01187 - 3.2.1.20 1.004e-218 705.0
HFD3_k127_206279_20 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001104 280.0
HFD3_k127_206279_21 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001247 295.0
HFD3_k127_206279_22 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000373 279.0
HFD3_k127_206279_23 TIM-barrel fold metal-dependent hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003835 275.0
HFD3_k127_206279_24 Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate K00452 - 1.13.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000001864 245.0
HFD3_k127_206279_25 PFAM MOSC domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000003961 239.0
HFD3_k127_206279_26 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.00000000000000000000000000000000000000000000000000000000000001264 222.0
HFD3_k127_206279_27 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000001841 210.0
HFD3_k127_206279_28 MaoC like domain - - - 0.0000000000000000000000000000000000000000000000001576 192.0
HFD3_k127_206279_29 ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000000000001498 194.0
HFD3_k127_206279_3 Periplasmic binding protein domain K01999 - - 3.31e-202 635.0
HFD3_k127_206279_30 Phosphoesterase K07095 - - 0.0000000000000000000000000000000000000000000001283 173.0
HFD3_k127_206279_31 PFAM 4-hydroxyphenylacetate 3-hydroxylase K00483 - 1.14.14.9 0.0000000000000000000000000000000000000002265 168.0
HFD3_k127_206279_32 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000004315 156.0
HFD3_k127_206279_33 cellulose binding - - - 0.00000000000000000000000000000002744 143.0
HFD3_k127_206279_34 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000111 103.0
HFD3_k127_206279_35 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.00000000000000000000003407 110.0
HFD3_k127_206279_36 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000001166 95.0
HFD3_k127_206279_37 Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate K00451 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0003824,GO:0004411,GO:0005488,GO:0005506,GO:0005575,GO:0006082,GO:0006355,GO:0006520,GO:0006558,GO:0006559,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0017144,GO:0019219,GO:0019222,GO:0019439,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0042737,GO:0043167,GO:0043169,GO:0043436,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0045892,GO:0045934,GO:0046395,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051213,GO:0051252,GO:0051253,GO:0055114,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0140110,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902221,GO:1902222,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 1.13.11.5 0.0000000000000002392 90.0
HFD3_k127_206279_38 PRC-barrel domain - - - 0.0000003482 61.0
HFD3_k127_206279_39 periplasmic or secreted lipoprotein - - - 0.000003131 58.0
HFD3_k127_206279_4 FAD dependent oxidoreductase K13796 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007082 613.0
HFD3_k127_206279_40 Protease prsW family - - - 0.00002134 51.0
HFD3_k127_206279_41 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00004446 49.0
HFD3_k127_206279_5 FAD dependent oxidoreductase K13796 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 594.0
HFD3_k127_206279_6 AMP-binding enzyme C-terminal domain K02182 - 6.2.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 584.0
HFD3_k127_206279_7 His Kinase A (phosphoacceptor) domain K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006548 471.0
HFD3_k127_206279_8 Phosphoenolpyruvate phosphomutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004541 413.0
HFD3_k127_206279_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006261 415.0
HFD3_k127_2063598_0 Beta-lactamase - - - 3.828e-204 661.0
HFD3_k127_2063598_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 557.0
HFD3_k127_2063598_10 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000001043 227.0
HFD3_k127_2063598_11 pyruvate kinase activity K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000002433 218.0
HFD3_k127_2063598_12 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.0000000000000000000000000000000000000000000000000000002282 209.0
HFD3_k127_2063598_13 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000001111 199.0
HFD3_k127_2063598_14 endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000001847 135.0
HFD3_k127_2063598_15 Thioredoxin domain - - - 0.000000000000000000000001083 109.0
HFD3_k127_2063598_16 Thioredoxin domain - - - 0.000000000000000001759 87.0
HFD3_k127_2063598_17 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.000000000000002933 83.0
HFD3_k127_2063598_18 Protein of unknown function, DUF393 - - - 0.00000000002461 70.0
HFD3_k127_2063598_19 DinB superfamily - - - 0.00002102 54.0
HFD3_k127_2063598_2 PFAM Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 487.0
HFD3_k127_2063598_3 Belongs to the UbiD family K16874 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004733 448.0
HFD3_k127_2063598_4 Thiamine pyrophosphate enzyme, central domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 379.0
HFD3_k127_2063598_5 Putative glycosyl hydrolase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006563 314.0
HFD3_k127_2063598_6 of the alpha beta superfamily K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 289.0
HFD3_k127_2063598_7 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001515 287.0
HFD3_k127_2063598_8 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000002359 280.0
HFD3_k127_2063598_9 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004204 252.0
HFD3_k127_2069651_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005747 409.0
HFD3_k127_2069651_1 S-adenosylhomocysteine deaminase activity K01305,K15358 - 3.5.2.18 0.000026 53.0
HFD3_k127_2091057_0 PFAM iron-containing alcohol dehydrogenase K00001,K11173,K13954 - 1.1.1.1,1.1.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 549.0
HFD3_k127_2091057_1 Tripartite tricarboxylate transporter TctA family K07793 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 546.0
HFD3_k127_2091057_12 Tripartite tricarboxylate transporter TctB family - - - 0.0001357 50.0
HFD3_k127_2091057_2 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005366 313.0
HFD3_k127_2091057_3 PFAM phospholipase Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 321.0
HFD3_k127_2091057_4 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001177 297.0
HFD3_k127_2091057_5 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000008531 177.0
HFD3_k127_2091057_6 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain K03520,K11177 - 1.17.1.4,1.2.5.3 0.0000000000000000000000000000000000002014 148.0
HFD3_k127_2091057_8 - - - - 0.0000000000000001021 87.0
HFD3_k127_209894_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K02887,K03628 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 1.859e-205 664.0
HFD3_k127_209894_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009702 518.0
HFD3_k127_209894_10 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006686 258.0
HFD3_k127_209894_11 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000002574 234.0
HFD3_k127_209894_12 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000001942 240.0
HFD3_k127_209894_13 imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000002217 245.0
HFD3_k127_209894_14 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000001172 222.0
HFD3_k127_209894_15 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000003001 228.0
HFD3_k127_209894_16 Histidine biosynthesis bifunctional protein hisIE K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000002412 210.0
HFD3_k127_209894_17 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.0000000000000000000000000000000000000000000000000001119 192.0
HFD3_k127_209894_18 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.0000000000000000000000000000000000000000000000000003799 198.0
HFD3_k127_209894_19 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.000000000000000000000000000000000000000000000001476 194.0
HFD3_k127_209894_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 524.0
HFD3_k127_209894_20 MlaD protein K02067 - - 0.000000000000000000000000000000000000000004415 170.0
HFD3_k127_209894_21 SurA N-terminal domain K03771 - 5.2.1.8 0.0000000000000000000000000000000000001237 163.0
HFD3_k127_209894_22 Binds the 23S rRNA K02909 - - 0.000000000000000000004084 108.0
HFD3_k127_209894_23 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000304 81.0
HFD3_k127_209894_25 - - - - 0.000000001104 70.0
HFD3_k127_209894_3 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 487.0
HFD3_k127_209894_4 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005196 480.0
HFD3_k127_209894_5 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 428.0
HFD3_k127_209894_6 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 407.0
HFD3_k127_209894_7 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 355.0
HFD3_k127_209894_8 Large family of predicted nucleotide-binding domains - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001952 288.0
HFD3_k127_209894_9 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000007704 265.0
HFD3_k127_2105733_0 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007108 489.0
HFD3_k127_2105733_1 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit K11690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 406.0
HFD3_k127_2105733_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000000006602 223.0
HFD3_k127_2105733_3 ferredoxin - GO:0001666,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0009628,GO:0036293,GO:0043207,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0070482,GO:0075136 - 0.000000000000000000000000000000003824 130.0
HFD3_k127_2132804_0 Secreted repeat of unknown function - - - 0.000000000000000000000000000000000000000000000000000005923 201.0
HFD3_k127_2132804_1 YceI-like domain - - - 0.0000000000000001015 89.0
HFD3_k127_2132804_2 best DB hits BLAST gb AAD45539.1 - - - 0.0003437 49.0
HFD3_k127_2154089_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1084.0
HFD3_k127_2154089_1 acetyl-coa acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 564.0
HFD3_k127_2154089_10 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000009578 162.0
HFD3_k127_2154089_11 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000000000000000009988 166.0
HFD3_k127_2154089_12 belongs to the Fur family K03711,K09825 - - 0.0000000000000000000000000001383 121.0
HFD3_k127_2154089_13 cyclic nucleotide-binding - - - 0.00000000000000000003702 99.0
HFD3_k127_2154089_14 - - - - 0.000000000000000001156 90.0
HFD3_k127_2154089_15 Protein of unknown function (DUF3047) - - - 0.00000000000008432 80.0
HFD3_k127_2154089_2 PFAM Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 503.0
HFD3_k127_2154089_3 4 iron, 4 sulfur cluster binding K00113,K00176,K05524,K13795,K13796 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.1.5.3,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 383.0
HFD3_k127_2154089_4 Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 321.0
HFD3_k127_2154089_5 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 321.0
HFD3_k127_2154089_6 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004478 279.0
HFD3_k127_2154089_7 Uncharacterised MFS-type transporter YbfB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001584 260.0
HFD3_k127_2154089_8 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000008327 236.0
HFD3_k127_2154089_9 Urate oxidase N-terminal - - - 0.000000000000000000000000000000000000000000000002715 181.0
HFD3_k127_2154549_0 aminotransferase class I and II K14261 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000809 571.0
HFD3_k127_2154549_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00928,K12524 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3,2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007401 509.0
HFD3_k127_2154549_10 Competence protein ComEA K02237 - - 0.00000000001137 71.0
HFD3_k127_2154549_2 homoserine dehydrogenase K00003 GO:0003674,GO:0003824,GO:0004412,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 458.0
HFD3_k127_2154549_3 Metallo-beta-lactamase superfamily K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 379.0
HFD3_k127_2154549_4 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 354.0
HFD3_k127_2154549_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 314.0
HFD3_k127_2154549_6 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002903 253.0
HFD3_k127_2154549_7 Peptidase, M23 - - - 0.0000000000000000000000000000000000000003918 160.0
HFD3_k127_2154549_8 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000001654 152.0
HFD3_k127_2154549_9 Putative MetA-pathway of phenol degradation - - - 0.0000000000000000000000000000006689 136.0
HFD3_k127_2221641_0 xanthine dehydrogenase activity K03520 - 1.2.5.3 1.1e-317 990.0
HFD3_k127_2221641_1 DNA polymerase type-B family K02336 - 2.7.7.7 6.842e-217 706.0
HFD3_k127_2221641_10 Belongs to the LarC family K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008763 356.0
HFD3_k127_2221641_11 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007675 345.0
HFD3_k127_2221641_12 MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 358.0
HFD3_k127_2221641_13 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 334.0
HFD3_k127_2221641_14 xanthine dehydrogenase activity K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 314.0
HFD3_k127_2221641_15 tRNA processing K06864,K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 310.0
HFD3_k127_2221641_16 VWA domain containing CoxE-like protein K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 317.0
HFD3_k127_2221641_17 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 328.0
HFD3_k127_2221641_18 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001506 275.0
HFD3_k127_2221641_19 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007905 287.0
HFD3_k127_2221641_2 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007455 443.0
HFD3_k127_2221641_20 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000004965 234.0
HFD3_k127_2221641_21 XdhC and CoxI family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000013 231.0
HFD3_k127_2221641_22 'Molybdopterin - - - 0.0000000000000000000000000000000000000000000000000000000004953 222.0
HFD3_k127_2221641_23 serine-type endopeptidase activity K04691,K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000005649 192.0
HFD3_k127_2221641_24 photosynthesis - - - 0.00000000000000000000000000000000000000000000000001257 186.0
HFD3_k127_2221641_25 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.000000000000000000000000000000000000000002116 164.0
HFD3_k127_2221641_26 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000005414 171.0
HFD3_k127_2221641_27 Molybdopterin converting factor, small subunit K03636 - - 0.00000000000000000000000000003885 119.0
HFD3_k127_2221641_28 RNA recognition motif - - - 0.0000000000000000000000002222 109.0
HFD3_k127_2221641_29 SUF system FeS assembly protein, NifU family K04488 - - 0.000000000000000000000002117 109.0
HFD3_k127_2221641_3 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005219 430.0
HFD3_k127_2221641_30 RDD family - - - 0.00000000000003708 82.0
HFD3_k127_2221641_31 Virulence factor BrkB K07058 - - 0.000000000007044 76.0
HFD3_k127_2221641_32 Domain of unknown function (DUF309) K09763 - - 0.000000008692 69.0
HFD3_k127_2221641_33 synthase - - - 0.00002906 57.0
HFD3_k127_2221641_34 4-Hydroxyphenylpyruvate dioxygenase K00406,K05606,K17315 - 5.1.99.1 0.00003024 47.0
HFD3_k127_2221641_35 Rhodanese-like domain - - - 0.0001868 53.0
HFD3_k127_2221641_4 COG0524 Sugar kinases, ribokinase family K00847 - 2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 415.0
HFD3_k127_2221641_5 MOFRL family K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007347 413.0
HFD3_k127_2221641_6 Associated with various cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 376.0
HFD3_k127_2221641_7 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005722 372.0
HFD3_k127_2221641_8 TIGRFAM molybdenum cofactor synthesis K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 362.0
HFD3_k127_2221641_9 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 366.0
HFD3_k127_2226865_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.2.1.33,4.2.1.35 2.416e-236 737.0
HFD3_k127_2226865_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 4.399e-211 674.0
HFD3_k127_2226865_10 biosynthesis - - - 0.00004294 54.0
HFD3_k127_2226865_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006788 571.0
HFD3_k127_2226865_3 short-chain dehydrogenase reductase SDR K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 332.0
HFD3_k127_2226865_4 DNA-binding transcription factor activity K02521 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 325.0
HFD3_k127_2226865_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000001744 256.0
HFD3_k127_2226865_6 SMART AAA ATPase K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005943 270.0
HFD3_k127_2226865_7 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000005791 158.0
HFD3_k127_2226865_8 PFAM Polysaccharide export protein - - - 0.000000000000000000000000000000000001527 148.0
HFD3_k127_2226865_9 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000201 97.0
HFD3_k127_2286434_0 acyl-coa dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 573.0
HFD3_k127_2286434_1 dipeptide transport K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006479 508.0
HFD3_k127_2286434_10 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007873 276.0
HFD3_k127_2286434_11 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002468 274.0
HFD3_k127_2286434_12 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.000000000000000000000000000000000000000000000000000000000000002182 228.0
HFD3_k127_2286434_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000003825 220.0
HFD3_k127_2286434_14 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000001765 182.0
HFD3_k127_2286434_15 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.0000000000000000000000000000000000000000000000004535 184.0
HFD3_k127_2286434_16 Predicted membrane protein (DUF2339) - - - 0.000000000000000000000000000000000000000000000002146 197.0
HFD3_k127_2286434_17 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000006441 176.0
HFD3_k127_2286434_18 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000004184 175.0
HFD3_k127_2286434_19 PFAM FAD dependent oxidoreductase K00301 - 1.5.3.1 0.00000000000000000000000000000000000000000009004 175.0
HFD3_k127_2286434_2 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005834 385.0
HFD3_k127_2286434_20 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000000000769 150.0
HFD3_k127_2286434_21 Protein of unknown function (DUF3752) - - - 0.00000000000000000000000001505 118.0
HFD3_k127_2286434_22 TPM domain - - - 0.0000000000000000000003067 110.0
HFD3_k127_2286434_23 Carboxymuconolactone decarboxylase family - - - 0.00000001549 61.0
HFD3_k127_2286434_3 Alcohol dehydrogenase GroES-like domain K00001,K00008 - 1.1.1.1,1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009154 370.0
HFD3_k127_2286434_4 HMGL-like K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 343.0
HFD3_k127_2286434_5 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 342.0
HFD3_k127_2286434_6 Microcin C7 resistance K01297 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009050,GO:0009056,GO:0009254,GO:0009987,GO:0016787,GO:0019538,GO:0030203,GO:0034641,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 338.0
HFD3_k127_2286434_7 Putative serine dehydratase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 320.0
HFD3_k127_2286434_8 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 323.0
HFD3_k127_2286434_9 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002185 276.0
HFD3_k127_2313783_0 PFAM multicopper oxidase type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008461 383.0
HFD3_k127_2313783_1 iron dependent repressor K03709 - - 0.0000000000000000000000000000000000000000000000000000000000004743 229.0
HFD3_k127_2313783_2 transporter - - - 0.0000000000000000000000000000000000000000000000001885 185.0
HFD3_k127_2313783_3 COG0720 6-pyruvoyl-tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000002252 107.0
HFD3_k127_2313783_4 - - - - 0.0000001054 55.0
HFD3_k127_2341488_0 Luciferase-like monooxygenase K14733 - 1.14.13.107 2.495e-228 716.0
HFD3_k127_2341488_1 Glycosyl hydrolases family 15 - - - 3.032e-219 696.0
HFD3_k127_2341488_2 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003349 286.0
HFD3_k127_2341488_3 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008362 282.0
HFD3_k127_2341488_4 COG4177 ABC-type branched-chain amino acid transport system, permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000006888 241.0
HFD3_k127_2341488_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000002332 218.0
HFD3_k127_2341488_6 ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000001428 222.0
HFD3_k127_2341488_7 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000001823 222.0
HFD3_k127_2341488_8 Dienelactone hydrolase family - - - 0.0000000000000001726 82.0
HFD3_k127_2348344_0 Class II Aldolase and Adducin N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001351 242.0
HFD3_k127_2348344_1 NIPSNAP - - - 0.0000000000000000000000000000000000000000006263 173.0
HFD3_k127_2348344_2 hydrolases or acyltransferases alpha beta hydrolase superfamily - - - 0.0000000000000000000000000000000006729 142.0
HFD3_k127_2357433_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006555 510.0
HFD3_k127_2357433_1 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.00000000000000000000000000891 115.0
HFD3_k127_2377693_0 Hydantoinase/oxoprolinase - - - 3.915e-243 765.0
HFD3_k127_2377693_1 N-methylhydantoinase A acetone carboxylase, beta subunit K01473 - 3.5.2.14 3.477e-235 748.0
HFD3_k127_2377693_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000003138 237.0
HFD3_k127_2381002_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016469,GO:0030312,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 3.6.3.14 5.661e-242 760.0
HFD3_k127_2381002_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 390.0
HFD3_k127_2381002_2 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 312.0
HFD3_k127_2381002_3 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006388 254.0
HFD3_k127_2381002_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000002529 119.0
HFD3_k127_2381002_5 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000002008 107.0
HFD3_k127_2384097_0 GntR family transcriptional regulator K00375,K05825 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009298 503.0
HFD3_k127_2384097_1 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000005735 158.0
HFD3_k127_2384097_2 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000001096 138.0
HFD3_k127_2384097_3 domain protein - - - 0.00000000000000000000000000000000002021 147.0
HFD3_k127_2404253_1 N-formylglutamate amidohydrolase K01458 - 3.5.1.68 0.0000000000000000006501 98.0
HFD3_k127_2404253_2 SMP-30/Gluconolaconase/LRE-like region K02352 - - 0.0000000002361 63.0
HFD3_k127_2404253_3 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 0.0000001319 53.0
HFD3_k127_2427162_0 MutS domain I K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 8.979e-229 737.0
HFD3_k127_2427162_1 Ribosomal protein S1 K02945,K03527 - 1.17.7.4 2.463e-214 680.0
HFD3_k127_2427162_10 Fe-S oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 357.0
HFD3_k127_2427162_11 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 374.0
HFD3_k127_2427162_12 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 311.0
HFD3_k127_2427162_13 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006467 321.0
HFD3_k127_2427162_14 inositol 2-dehydrogenase activity K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 299.0
HFD3_k127_2427162_15 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003496 276.0
HFD3_k127_2427162_16 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000915 278.0
HFD3_k127_2427162_17 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000382 262.0
HFD3_k127_2427162_18 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000973 265.0
HFD3_k127_2427162_19 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000001125 254.0
HFD3_k127_2427162_2 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 578.0
HFD3_k127_2427162_20 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004179 253.0
HFD3_k127_2427162_21 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000004459 246.0
HFD3_k127_2427162_22 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000005545 247.0
HFD3_k127_2427162_23 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000001244 228.0
HFD3_k127_2427162_24 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000006372 241.0
HFD3_k127_2427162_25 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000002039 224.0
HFD3_k127_2427162_26 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02527,K02841,K02843,K12982 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000001607 225.0
HFD3_k127_2427162_27 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000002088 211.0
HFD3_k127_2427162_28 transferase activity, transferring glycosyl groups K02844 - - 0.00000000000000000000000000000000000000000000000000001316 215.0
HFD3_k127_2427162_29 Cytidylate kinase K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000007307 207.0
HFD3_k127_2427162_3 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 557.0
HFD3_k127_2427162_30 bis(5'-adenosyl)-triphosphatase activity K19710 GO:0003674,GO:0003824,GO:0003877,GO:0004551,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008796,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0015959,GO:0015961,GO:0015965,GO:0015967,GO:0016020,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070566,GO:0071704,GO:0071944,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 2.7.7.53 0.0000000000000000000000000000000000000000000000004141 179.0
HFD3_k127_2427162_31 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000002937 185.0
HFD3_k127_2427162_32 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000003951 166.0
HFD3_k127_2427162_33 pyrroloquinoline quinone binding - - - 0.000000000000000000000000000000000000000006207 175.0
HFD3_k127_2427162_34 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000215 158.0
HFD3_k127_2427162_35 Psort location Cytoplasmic, score 8.96 K09949 - - 0.00000000000000000000000000000000000001057 166.0
HFD3_k127_2427162_36 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000273 155.0
HFD3_k127_2427162_37 Domain of unknown function (DUF374) K09778 - - 0.000000000000000000000000000000000004202 147.0
HFD3_k127_2427162_38 CDP-alcohol phosphatidyltransferase K00995,K08744 - 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000001222 139.0
HFD3_k127_2427162_39 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves - - - 0.0000000000000000000000000000000002799 151.0
HFD3_k127_2427162_4 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 437.0
HFD3_k127_2427162_40 transferase activity, transferring glycosyl groups K00754 - - 0.0000000000000000000000000000000007649 145.0
HFD3_k127_2427162_41 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000002853 144.0
HFD3_k127_2427162_42 regulation of translation K05788 - - 0.00000000000000000000000000000001435 130.0
HFD3_k127_2427162_43 PFAM peptidase - - - 0.0000000000000000000000000000008595 134.0
HFD3_k127_2427162_44 domain protein K12516 - - 0.000000000000000000000000002159 116.0
HFD3_k127_2427162_45 Regulatory protein - - - 0.0000000000000000000000001842 109.0
HFD3_k127_2427162_46 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000003278 104.0
HFD3_k127_2427162_47 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.000000000000000002383 88.0
HFD3_k127_2427162_48 Outer membrane protein (OmpH-like) K06142 - - 0.000000003114 61.0
HFD3_k127_2427162_49 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000007264 58.0
HFD3_k127_2427162_5 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004261 422.0
HFD3_k127_2427162_51 Major facilitator Superfamily - - - 0.000005312 50.0
HFD3_k127_2427162_6 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 414.0
HFD3_k127_2427162_7 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005059 409.0
HFD3_k127_2427162_8 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009711 387.0
HFD3_k127_2427162_9 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 365.0
HFD3_k127_2436511_0 Xanthine dehydrogenase K03520 - 1.2.5.3 4.326e-281 886.0
HFD3_k127_2436511_1 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004115 297.0
HFD3_k127_2436511_2 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000149 294.0
HFD3_k127_2436511_3 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000002911 215.0
HFD3_k127_2436511_4 FAD binding domain - - - 0.000000000000000000000000000000005695 140.0
HFD3_k127_2436511_5 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K10676 - 1.14.13.20 0.0000000000000002702 88.0
HFD3_k127_2456517_0 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain K01596,K01610 - 4.1.1.32,4.1.1.49 2.753e-257 806.0
HFD3_k127_2456517_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 323.0
HFD3_k127_2456517_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 299.0
HFD3_k127_2456517_3 hydrolase, family 3 K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000002757 270.0
HFD3_k127_2456517_4 - - - - 0.000000000000000000000000000000000000000000000001621 191.0
HFD3_k127_2456517_5 Thioesterase superfamily K02614 - - 0.000000000000004661 81.0
HFD3_k127_2456526_0 Hydantoinaseoxoprolinase domain protein K01469,K01473 - 3.5.2.14,3.5.2.9 1.432e-252 797.0
HFD3_k127_2456526_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 6.556e-206 649.0
HFD3_k127_2456526_10 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000097 339.0
HFD3_k127_2456526_11 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 320.0
HFD3_k127_2456526_12 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 316.0
HFD3_k127_2456526_13 CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 319.0
HFD3_k127_2456526_14 Methionine aminopeptidase K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008654 314.0
HFD3_k127_2456526_15 ABC transporter, ATP-binding protein K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 299.0
HFD3_k127_2456526_16 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000128 264.0
HFD3_k127_2456526_17 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002781 263.0
HFD3_k127_2456526_18 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000006818 271.0
HFD3_k127_2456526_19 Transporter associated domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007164 284.0
HFD3_k127_2456526_2 General secretory system II protein E domain protein K02652 - - 1.619e-195 630.0
HFD3_k127_2456526_20 GTP binding K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001791 252.0
HFD3_k127_2456526_21 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234 - 0.00000000000000000000000000000000000000000000000000000000000000000000001409 248.0
HFD3_k127_2456526_22 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000006966 246.0
HFD3_k127_2456526_23 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000003655 249.0
HFD3_k127_2456526_24 Iron-containing redox enzyme K06137 - 1.3.3.11 0.000000000000000000000000000000000000000000000000000000000000000000004873 242.0
HFD3_k127_2456526_25 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000001038 254.0
HFD3_k127_2456526_26 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000008799 232.0
HFD3_k127_2456526_27 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000001259 237.0
HFD3_k127_2456526_28 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000001027 217.0
HFD3_k127_2456526_29 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000002967 210.0
HFD3_k127_2456526_3 PFAM Hydantoinase B oxoprolinase K01469,K01474 - 3.5.2.14,3.5.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 622.0
HFD3_k127_2456526_30 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000001069 211.0
HFD3_k127_2456526_31 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000001799 197.0
HFD3_k127_2456526_32 type IV pilus secretin PilQ K02666 - - 0.000000000000000000000000000000000000000000000000000471 204.0
HFD3_k127_2456526_33 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000003599 183.0
HFD3_k127_2456526_34 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000000000008947 183.0
HFD3_k127_2456526_35 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000000000000000002939 180.0
HFD3_k127_2456526_36 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000005694 164.0
HFD3_k127_2456526_37 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000001787 169.0
HFD3_k127_2456526_38 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000004707 162.0
HFD3_k127_2456526_39 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000002506 162.0
HFD3_k127_2456526_4 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 554.0
HFD3_k127_2456526_40 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000001017 154.0
HFD3_k127_2456526_41 Nodulation protein S (NodS) - - - 0.00000000000000000000000000000000000145 159.0
HFD3_k127_2456526_42 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000004379 139.0
HFD3_k127_2456526_43 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.0000000000000000000000000000000003627 138.0
HFD3_k127_2456526_44 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000001093 137.0
HFD3_k127_2456526_45 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.000000000000000000000000000000005247 132.0
HFD3_k127_2456526_46 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000253 134.0
HFD3_k127_2456526_47 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000006682 133.0
HFD3_k127_2456526_48 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000002554 140.0
HFD3_k127_2456526_49 Ribosomal protein L22p/L17e K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000003736 115.0
HFD3_k127_2456526_5 branched-chain amino acid transport system, permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 451.0
HFD3_k127_2456526_50 cheY-homologous receiver domain - - - 0.000000000000000000000000004946 123.0
HFD3_k127_2456526_51 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000000000132 112.0
HFD3_k127_2456526_52 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000003327 105.0
HFD3_k127_2456526_53 Roadblock/LC7 domain - - - 0.0000000000000000000000014 117.0
HFD3_k127_2456526_54 (Rieske (2Fe-2S) domain) K00363,K05710 - 1.7.1.15 0.0000000000000000000000143 104.0
HFD3_k127_2456526_55 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000002179 95.0
HFD3_k127_2456526_56 Tetratricopeptide repeat K00661,K18626 - 2.3.1.79 0.000000000000001118 85.0
HFD3_k127_2456526_57 Ribosomal protein L30 K02907 - - 0.00000000000001533 76.0
HFD3_k127_2456526_58 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000193 72.0
HFD3_k127_2456526_59 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000004961 68.0
HFD3_k127_2456526_6 arsenite transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 430.0
HFD3_k127_2456526_60 Haem-degrading - - - 0.000000000006586 75.0
HFD3_k127_2456526_61 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000001328 65.0
HFD3_k127_2456526_62 Tetratricopeptide repeat - - - 0.000001261 59.0
HFD3_k127_2456526_63 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00003382 55.0
HFD3_k127_2456526_7 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000516 423.0
HFD3_k127_2456526_8 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 389.0
HFD3_k127_2456526_9 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 360.0
HFD3_k127_2462856_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 0.0000000000000000000000000000000000003374 146.0
HFD3_k127_2462856_1 PFAM Outer membrane lipoprotein Slp K07285 - - 0.000000000000000000000000001283 121.0
HFD3_k127_2479513_0 Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000497 494.0
HFD3_k127_2479513_1 High confidence in function and specificity K07481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007109 260.0
HFD3_k127_2479513_3 Protein of unknown function (DUF1254) - - - 0.0000000002521 63.0
HFD3_k127_2479513_4 Histidine Phosphotransfer domain - - - 0.000001781 58.0
HFD3_k127_2480784_0 3-isopropylmalate dehydrogenase activity K00052,K05824 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0047046,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85,1.1.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001102 286.0
HFD3_k127_2480784_1 Protein of unknown function (DUF3830) - - - 0.0000000000000000000000000000000000000000000000000000313 210.0
HFD3_k127_2480784_2 - - - - 0.00000000000000000000000000000000000000000000000000192 206.0
HFD3_k127_2480784_3 COG0471 Di- and tricarboxylate transporters K14445 - - 0.0000000000000000000000000000004572 139.0
HFD3_k127_2480784_4 Thioesterase superfamily - - - 0.000000000000000001183 97.0
HFD3_k127_2482726_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 5.601e-268 845.0
HFD3_k127_2482726_1 secondary active sulfate transmembrane transporter activity K06901 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007864 501.0
HFD3_k127_2482726_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000232 122.0
HFD3_k127_2488024_0 Transglutaminase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 333.0
HFD3_k127_2488024_1 PFAM FAD dependent oxidoreductase K00285 - 1.4.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 310.0
HFD3_k127_2488024_2 Domain of unknown function (DUF1989) K09967 - - 0.00000000000000000000000000000000000000000000000000000000000003186 228.0
HFD3_k127_2488024_3 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000002125 204.0
HFD3_k127_2488024_4 FAD dependent oxidoreductase K00285 - 1.4.5.1 0.000000000000000000000000000000000000003845 152.0
HFD3_k127_2488024_5 2'-5' RNA ligase superfamily - - - 0.0000000000000006043 85.0
HFD3_k127_2491523_0 serine-type peptidase activity K08676 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006264 251.0
HFD3_k127_2491523_1 Domain of unknown function (DUF5117) - - - 0.00000000000000000000000000000000000000000000000000008515 197.0
HFD3_k127_2519701_0 ABC-type dipeptide transport system periplasmic component K02035 - - 1.932e-269 836.0
HFD3_k127_2519701_1 (ABC) transporter K15738 - - 4.055e-198 634.0
HFD3_k127_2519701_10 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006435 342.0
HFD3_k127_2519701_11 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 345.0
HFD3_k127_2519701_12 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004003 318.0
HFD3_k127_2519701_13 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009224 287.0
HFD3_k127_2519701_14 Phosphoadenosine phosphosulfate reductase family K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002388 285.0
HFD3_k127_2519701_15 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002564 279.0
HFD3_k127_2519701_16 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000427 275.0
HFD3_k127_2519701_18 - - - - 0.000000000000000000000000000000000000000000000000000003617 195.0
HFD3_k127_2519701_19 - - - - 0.000000000000000000000000000000000000000000000000004229 189.0
HFD3_k127_2519701_2 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 459.0
HFD3_k127_2519701_20 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000006425 200.0
HFD3_k127_2519701_21 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000001938 185.0
HFD3_k127_2519701_22 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000001102 193.0
HFD3_k127_2519701_23 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000001146 190.0
HFD3_k127_2519701_24 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000000000000000000008776 164.0
HFD3_k127_2519701_25 Sugar (and other) transporter K08161 - - 0.000000000000000000000000000000000000000005318 169.0
HFD3_k127_2519701_26 MaoC like domain - - - 0.000000000000000000000000000000000000005241 158.0
HFD3_k127_2519701_27 Protein of unknown function, DUF547 - - - 0.00000000000000000000000000000000002973 153.0
HFD3_k127_2519701_28 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000008753 146.0
HFD3_k127_2519701_29 Cytidylyltransferase K00983,K18431 - 2.7.7.43,2.7.7.82 0.00000000000003686 78.0
HFD3_k127_2519701_3 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 383.0
HFD3_k127_2519701_4 PFAM SMP-30 Gluconolaconase K08685 - 1.4.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 386.0
HFD3_k127_2519701_5 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007654 381.0
HFD3_k127_2519701_6 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009444 383.0
HFD3_k127_2519701_7 Lactonase, 7-bladed beta-propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007499 371.0
HFD3_k127_2519701_8 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 364.0
HFD3_k127_2519701_9 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 355.0
HFD3_k127_2522971_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 2.328e-247 771.0
HFD3_k127_2522971_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 355.0
HFD3_k127_2522971_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016469,GO:0030312,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 3.6.3.14 0.00000000000000000000000000000000000000000000000000009094 189.0
HFD3_k127_2522971_3 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.0000000000000000000000000000000000000000000000001973 186.0
HFD3_k127_2522971_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000002942 135.0
HFD3_k127_2522971_5 phosphate regulon transcriptional regulatory protein PhoB K07657,K07659 - - 0.0000000000000000000000000002069 119.0
HFD3_k127_2534173_0 Belongs to the TPP enzyme family K01576 - 4.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 521.0
HFD3_k127_2534173_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00015 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006195 354.0
HFD3_k127_2534173_2 Belongs to the UbiD family K16874 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 331.0
HFD3_k127_2534173_3 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 331.0
HFD3_k127_2534173_4 ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis K13527 GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 284.0
HFD3_k127_2534173_5 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000003939 222.0
HFD3_k127_2534173_6 Belongs to the ompA family - - - 0.0000000000000000000000002816 115.0
HFD3_k127_2534173_7 Ankyrin repeat K06867 - - 0.0000000000000000000508 107.0
HFD3_k127_2534173_8 AAA domain K02450 - - 0.0000000001443 76.0
HFD3_k127_2555587_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 3.828e-204 661.0
HFD3_k127_2555587_1 ABC-type dipeptide transport system periplasmic component K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 599.0
HFD3_k127_2555587_10 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 361.0
HFD3_k127_2555587_11 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009247 349.0
HFD3_k127_2555587_12 rieske 2fe-2s - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007373 347.0
HFD3_k127_2555587_13 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441 344.0
HFD3_k127_2555587_14 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008787 316.0
HFD3_k127_2555587_15 secondary active sulfate transmembrane transporter activity K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 325.0
HFD3_k127_2555587_16 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 306.0
HFD3_k127_2555587_17 aminopeptidase activity K18028 - 1.13.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005148 293.0
HFD3_k127_2555587_18 Carbon-nitrogen hydrolase K01431 - 3.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000006255 269.0
HFD3_k127_2555587_19 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001137 254.0
HFD3_k127_2555587_2 Glutamine synthetase N-terminal domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006375 580.0
HFD3_k127_2555587_20 Pkd domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000003711 252.0
HFD3_k127_2555587_21 Bacterial extracellular solute-binding protein K02020 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0040007,GO:0042597,GO:0043167,GO:0043168,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704 - 0.0000000000000000000000000000000000000000000000000000000000007909 220.0
HFD3_k127_2555587_22 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.00000000000000000000000000000000000000000000000000000000004124 226.0
HFD3_k127_2555587_23 Predicted membrane protein (DUF2142) - - - 0.0000000000000000000000000000000000000000000000000000001318 212.0
HFD3_k127_2555587_24 Transcriptional regulator K21900 - - 0.0000000000000000000000000000000000000000000000000000103 201.0
HFD3_k127_2555587_25 Protein phosphatase 2C domain K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000009704 201.0
HFD3_k127_2555587_26 - - - - 0.000000000000000000000000000000000000000000002372 175.0
HFD3_k127_2555587_27 TRAP transporter, solute receptor (TAXI family K07080 - - 0.000000000000000000000000000000000000000000004136 177.0
HFD3_k127_2555587_28 COG0411 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.00000000000000000000000000000000000000000002238 171.0
HFD3_k127_2555587_29 - - - - 0.000000000000000000000000000000000000000001123 166.0
HFD3_k127_2555587_3 Periplasmic binding protein domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 530.0
HFD3_k127_2555587_30 Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000007664 167.0
HFD3_k127_2555587_31 PFAM Cell wall hydrolase - - - 0.0000000000000000000000000000000000000006626 160.0
HFD3_k127_2555587_32 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000006854 149.0
HFD3_k127_2555587_33 bacterial-type flagellum-dependent cell motility - - - 0.0000000000000000000000000000002323 141.0
HFD3_k127_2555587_34 Prolyl 4-hydroxylase alpha subunit homologues. K00472 - 1.14.11.2 0.00000000000000000000000005883 116.0
HFD3_k127_2555587_35 STAS domain K06378 - - 0.0000000000000000000000378 113.0
HFD3_k127_2555587_36 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000005536 98.0
HFD3_k127_2555587_37 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000002056 93.0
HFD3_k127_2555587_38 Histidine kinase-like ATPase domain - - - 0.0000000000000002712 84.0
HFD3_k127_2555587_39 response regulator, receiver - - - 0.00000000000464 79.0
HFD3_k127_2555587_4 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 452.0
HFD3_k127_2555587_40 Short C-terminal domain - - - 0.00000000008673 70.0
HFD3_k127_2555587_5 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 418.0
HFD3_k127_2555587_6 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 410.0
HFD3_k127_2555587_7 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 416.0
HFD3_k127_2555587_8 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 403.0
HFD3_k127_2555587_9 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 370.0
HFD3_k127_2566511_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003183 514.0
HFD3_k127_2566511_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170,K19071 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004047 478.0
HFD3_k127_2566511_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 427.0
HFD3_k127_2566511_3 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00171,K00172,K19072 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 338.0
HFD3_k127_2566511_4 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.000000000000000000000000000000000000000000000000004117 195.0
HFD3_k127_2566511_5 Redoxin K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000006298 171.0
HFD3_k127_2566511_6 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000002585 142.0
HFD3_k127_2574998_0 Berberine and berberine like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 568.0
HFD3_k127_2574998_1 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 513.0
HFD3_k127_2574998_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001396 258.0
HFD3_k127_2574998_3 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.0000000000000000000000000007756 126.0
HFD3_k127_2574998_4 Subtilase family K13274,K14645 - - 0.000003077 57.0
HFD3_k127_2654881_0 AIR synthase related protein, N-terminal domain K01933,K11788 GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1,6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 374.0
HFD3_k127_2654881_1 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 372.0
HFD3_k127_2654881_2 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 365.0
HFD3_k127_2654881_3 LssY C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 310.0
HFD3_k127_2654881_4 Trypsin-like serine protease K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003429 290.0
HFD3_k127_2654881_5 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000003093 237.0
HFD3_k127_2654881_6 ABC-type nitrate sulfonate bicarbonate transport system, periplasmic component K02051 - - 0.000000000000000000000000000000000000000000002426 182.0
HFD3_k127_2654881_7 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000002762 133.0
HFD3_k127_2654881_8 Redoxin K11065 - 1.11.1.15 0.0001924 46.0
HFD3_k127_2687507_0 N-methylhydantoinase A acetone carboxylase, beta subunit K01469,K01473 - 3.5.2.14,3.5.2.9 6.755e-220 704.0
HFD3_k127_2687507_1 N-methylhydantoinase B acetone carboxylase alpha subunit - - - 1.738e-194 652.0
HFD3_k127_2687507_10 ligase activity, forming nitrogen-metal bonds K02230 - 6.6.1.2 0.000000000000000000000000000000000000000000000002191 186.0
HFD3_k127_2687507_11 - - - - 0.000000000000000000000000000000000003179 147.0
HFD3_k127_2687507_12 Thioredoxin K03672 - 1.8.1.8 0.00000000000000000000000000006622 126.0
HFD3_k127_2687507_13 Transcriptional regulatory protein, C terminal K07776 - - 0.000000000000000000002024 103.0
HFD3_k127_2687507_14 Nitrile hydratase beta subunit - - - 0.00000000000000000007037 101.0
HFD3_k127_2687507_2 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 627.0
HFD3_k127_2687507_3 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004957 430.0
HFD3_k127_2687507_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 410.0
HFD3_k127_2687507_5 transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002578 298.0
HFD3_k127_2687507_6 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001862 267.0
HFD3_k127_2687507_7 Nitrile hydratase beta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000003034 242.0
HFD3_k127_2687507_8 Nitrile hydratase K01721 - 4.2.1.84 0.000000000000000000000000000000000000000000000000000000000000000000114 244.0
HFD3_k127_2687507_9 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000002766 230.0
HFD3_k127_2696615_0 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 503.0
HFD3_k127_2696615_1 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006441 375.0
HFD3_k127_2696615_2 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000003784 90.0
HFD3_k127_2699217_0 Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0 1274.0
HFD3_k127_2699217_1 TrkA-N domain K03455,K10716 - - 1.08e-203 654.0
HFD3_k127_2699217_10 AhpC/TSA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 343.0
HFD3_k127_2699217_11 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 338.0
HFD3_k127_2699217_12 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 314.0
HFD3_k127_2699217_13 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000119 287.0
HFD3_k127_2699217_14 ATPases associated with a variety of cellular activities K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004816 291.0
HFD3_k127_2699217_15 aminotransferase K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000001028 275.0
HFD3_k127_2699217_16 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000122 262.0
HFD3_k127_2699217_17 Flagellar Assembly Protein A K09749 - - 0.0000000000000000000000000000000000000000000000000000000000000000002526 249.0
HFD3_k127_2699217_18 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000002048 136.0
HFD3_k127_2699217_19 Sigma-70, region 4 K03088 GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000004455 123.0
HFD3_k127_2699217_2 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009763 606.0
HFD3_k127_2699217_20 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000008821 96.0
HFD3_k127_2699217_21 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006171,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009187,GO:0009190,GO:0009259,GO:0009260,GO:0009975,GO:0009987,GO:0016020,GO:0016829,GO:0016849,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046058,GO:0046390,GO:0046483,GO:0052652,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.1 0.00000000000000003702 97.0
HFD3_k127_2699217_22 COG0747 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.00000000000001704 86.0
HFD3_k127_2699217_24 Putative zinc-finger - - - 0.00000004525 64.0
HFD3_k127_2699217_25 Right handed beta helix region - - - 0.00000009913 58.0
HFD3_k127_2699217_26 RibD C-terminal domain K00082 - 1.1.1.193 0.0000002557 61.0
HFD3_k127_2699217_27 Putative regulatory protein - - - 0.00003115 53.0
HFD3_k127_2699217_3 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 591.0
HFD3_k127_2699217_4 Domain of unknown function (DUF4331) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 571.0
HFD3_k127_2699217_5 ATP dependent DNA ligase C terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 522.0
HFD3_k127_2699217_6 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 479.0
HFD3_k127_2699217_7 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 440.0
HFD3_k127_2699217_8 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 421.0
HFD3_k127_2699217_9 High-affinity nickel-transport protein K07241 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 379.0
HFD3_k127_2719171_0 Fructose-bisphosphate aldolase class-I K01623 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006519 432.0
HFD3_k127_2719171_1 aldehyde-lyase activity K01621 - 4.1.2.22,4.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000754 321.0
HFD3_k127_2719171_2 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.000000000000000000001058 95.0
HFD3_k127_2754757_0 cellulose binding - - - 1.157e-221 691.0
HFD3_k127_2754757_1 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 511.0
HFD3_k127_2754757_10 Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006511 336.0
HFD3_k127_2754757_11 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 314.0
HFD3_k127_2754757_12 sigma factor activity K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 300.0
HFD3_k127_2754757_13 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005641 308.0
HFD3_k127_2754757_14 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 305.0
HFD3_k127_2754757_15 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008919 278.0
HFD3_k127_2754757_16 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003935 247.0
HFD3_k127_2754757_17 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000000000000000000000000000000000000000003719 229.0
HFD3_k127_2754757_19 Protein of unknown function (DUF1345) - - - 0.00000000000000000000000000000000000000000000000000000000000001875 222.0
HFD3_k127_2754757_2 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008468 471.0
HFD3_k127_2754757_20 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000001431 224.0
HFD3_k127_2754757_21 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000001549 208.0
HFD3_k127_2754757_22 Seven times multi-haem cytochrome CxxCH K10535 - 1.7.2.6 0.000000000000000000000000000000000000000000000000000002387 212.0
HFD3_k127_2754757_23 response regulator receiver K13041 - - 0.0000000000000000000000000000000000000000000000000002037 197.0
HFD3_k127_2754757_24 Domain of unknown function (DUF4337) - - - 0.00000000000000000000000000000000000000000000002483 189.0
HFD3_k127_2754757_25 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000002247 167.0
HFD3_k127_2754757_26 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.000000000000000000000000000000000000000309 151.0
HFD3_k127_2754757_27 YCII-related domain - - - 0.00000000000000000000000000000000000004235 157.0
HFD3_k127_2754757_28 PFAM Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000002562 138.0
HFD3_k127_2754757_29 Histidine kinase K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000004504 135.0
HFD3_k127_2754757_3 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 443.0
HFD3_k127_2754757_30 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.000000000000000000000000000115 132.0
HFD3_k127_2754757_31 Protein of unknown function (DUF1810) - - - 0.00000000000000000000000001802 115.0
HFD3_k127_2754757_32 cheY-homologous receiver domain - - - 0.00000000000000000000000009205 111.0
HFD3_k127_2754757_33 - - - - 0.0000000000000000000000123 106.0
HFD3_k127_2754757_34 - - - - 0.0000000000000000003328 98.0
HFD3_k127_2754757_35 - - - - 0.00000000000000004364 87.0
HFD3_k127_2754757_36 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000008983 78.0
HFD3_k127_2754757_37 YceI-like domain - - - 0.000000000000002454 83.0
HFD3_k127_2754757_39 - - - - 0.0000000000002181 82.0
HFD3_k127_2754757_4 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 453.0
HFD3_k127_2754757_40 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000008982 75.0
HFD3_k127_2754757_41 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000001216 64.0
HFD3_k127_2754757_42 Sugar ABC transporter permease K15771 - - 0.00000002359 59.0
HFD3_k127_2754757_43 mechanosensitive ion channel K03442,K16052 - - 0.00000008617 57.0
HFD3_k127_2754757_44 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.0000000873 65.0
HFD3_k127_2754757_45 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.000004351 57.0
HFD3_k127_2754757_46 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0001375 56.0
HFD3_k127_2754757_47 YCII-related domain - - - 0.0009522 42.0
HFD3_k127_2754757_5 PFAM ATP-binding region K02484,K07678 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009291 417.0
HFD3_k127_2754757_6 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007813 422.0
HFD3_k127_2754757_7 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 421.0
HFD3_k127_2754757_8 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005952 349.0
HFD3_k127_2754757_9 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 322.0
HFD3_k127_2758063_0 UDP-galactopyranose mutase K01854 - 5.4.99.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 445.0
HFD3_k127_2758063_1 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 409.0
HFD3_k127_2758063_2 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 334.0
HFD3_k127_2758063_3 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000001647 186.0
HFD3_k127_2758063_5 SMART Prolyl 4-hydroxylase, alpha subunit - - - 0.00000000000000000000000000000002032 145.0
HFD3_k127_2758063_6 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.00000000000000000000000000001665 123.0
HFD3_k127_2758063_7 Glycosyl transferase, family 2 - - - 0.0000000000000000000000002166 123.0
HFD3_k127_2758063_8 Domain of unknown function (DUF1330) - - - 0.0000000000000000000009722 98.0
HFD3_k127_2758063_9 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000002678 87.0
HFD3_k127_2788148_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1621.0
HFD3_k127_2788148_1 FAD dependent oxidoreductase K00109,K15736 - 1.1.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005766 473.0
HFD3_k127_2788148_10 PFAM import inner membrane translocase, subunit Tim44 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001486 256.0
HFD3_k127_2788148_11 MlaA lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000002619 219.0
HFD3_k127_2788148_12 Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000001877 194.0
HFD3_k127_2788148_13 PFAM Cupin 2, conserved barrel - - - 0.000000000000000000000000000000000000000000009341 180.0
HFD3_k127_2788148_14 Tim44 - - - 0.000000000000000000000000000000000000000006176 167.0
HFD3_k127_2788148_15 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000009889 148.0
HFD3_k127_2788148_16 Trypsin-like peptidase domain - - - 0.0000000000000000000000000006725 130.0
HFD3_k127_2788148_17 SNARE associated Golgi protein K03975 - - 0.000000000000000006983 98.0
HFD3_k127_2788148_18 Haloacid dehalogenase-like hydrolase K01101 - 3.1.3.41 0.000000000000000008824 90.0
HFD3_k127_2788148_19 PFAM Cyclic nucleotide-binding K03321,K10914 - - 0.00000000001233 70.0
HFD3_k127_2788148_2 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 471.0
HFD3_k127_2788148_3 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 472.0
HFD3_k127_2788148_4 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 382.0
HFD3_k127_2788148_5 PFAM binding-protein-dependent transport systems inner membrane component K02033,K12369,K13890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 309.0
HFD3_k127_2788148_6 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005606 320.0
HFD3_k127_2788148_7 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009809 296.0
HFD3_k127_2788148_8 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003612 289.0
HFD3_k127_2788148_9 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004966 277.0
HFD3_k127_2793015_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.894e-285 891.0
HFD3_k127_2793015_1 carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 2.717e-242 758.0
HFD3_k127_2793015_10 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 441.0
HFD3_k127_2793015_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 453.0
HFD3_k127_2793015_12 ATP synthesis coupled electron transport K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 448.0
HFD3_k127_2793015_13 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 441.0
HFD3_k127_2793015_14 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 414.0
HFD3_k127_2793015_15 Pyruvate dehydrogenase K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 407.0
HFD3_k127_2793015_16 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008891 401.0
HFD3_k127_2793015_17 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 406.0
HFD3_k127_2793015_18 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 403.0
HFD3_k127_2793015_19 COG1960 Acyl-CoA dehydrogenases K19966 - 3.13.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000925 412.0
HFD3_k127_2793015_2 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 7.878e-221 722.0
HFD3_k127_2793015_20 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 393.0
HFD3_k127_2793015_21 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 383.0
HFD3_k127_2793015_22 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009679 373.0
HFD3_k127_2793015_23 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00162,K00627 - 1.2.4.1,2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 389.0
HFD3_k127_2793015_24 PUA domain K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 370.0
HFD3_k127_2793015_25 quinone binding K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 331.0
HFD3_k127_2793015_26 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 293.0
HFD3_k127_2793015_27 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006722 288.0
HFD3_k127_2793015_28 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005559 281.0
HFD3_k127_2793015_29 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000003551 244.0
HFD3_k127_2793015_3 PFAM extracellular solute-binding protein, family 5 K02035,K13893 - - 7.828e-195 623.0
HFD3_k127_2793015_30 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000000000005201 231.0
HFD3_k127_2793015_31 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000002339 196.0
HFD3_k127_2793015_32 PFAM Phosphoribosyltransferase - - - 0.0000000000000000000000000000000000000000000009306 176.0
HFD3_k127_2793015_33 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000001796 166.0
HFD3_k127_2793015_34 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000002842 168.0
HFD3_k127_2793015_35 Cytidylyltransferase-like K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.000000000000000000000000000000000005473 147.0
HFD3_k127_2793015_36 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000000004973 126.0
HFD3_k127_2793015_37 Involved in DNA repair and RecF pathway recombination K03474,K03584 GO:0008150,GO:0009314,GO:0009628,GO:0050896 2.6.99.2 0.00000000000000000000000000000009055 134.0
HFD3_k127_2793015_38 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000000001644 126.0
HFD3_k127_2793015_39 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000000005655 127.0
HFD3_k127_2793015_4 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 580.0
HFD3_k127_2793015_40 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K00969,K09710 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 2.7.7.18 0.0000000000000000000000000000008624 128.0
HFD3_k127_2793015_41 - - - - 0.00000000000000000000000005115 109.0
HFD3_k127_2793015_42 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000001039 110.0
HFD3_k127_2793015_43 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000006366 108.0
HFD3_k127_2793015_44 Evidence 5 No homology to any previously reported sequences K03765 - - 0.00000000000000000000005272 115.0
HFD3_k127_2793015_45 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000005493 106.0
HFD3_k127_2793015_46 PFAM Preprotein translocase SecG subunit K03075 - - 0.00000000000000005374 87.0
HFD3_k127_2793015_47 Glycosyl transferase family 11 - - - 0.0000000000000002547 89.0
HFD3_k127_2793015_48 Putative regulatory protein - - - 0.0000000000000004969 84.0
HFD3_k127_2793015_49 Evidence 5 No homology to any previously reported sequences K03765 - - 0.00000000001507 75.0
HFD3_k127_2793015_5 Transglycosylase K05365,K05366,K21464 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 585.0
HFD3_k127_2793015_50 YtxH-like protein - - - 0.000002392 58.0
HFD3_k127_2793015_51 Evidence 5 No homology to any previously reported sequences K03765 - - 0.000009296 57.0
HFD3_k127_2793015_6 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006736 468.0
HFD3_k127_2793015_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 489.0
HFD3_k127_2793015_8 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 459.0
HFD3_k127_2793015_9 Pyridine nucleotide-disulphide oxidoreductase dimerisation region K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 449.0
HFD3_k127_280262_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K11177 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016903,GO:0030151,GO:0033554,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114 1.17.1.4 0.0 1081.0
HFD3_k127_280262_1 RESPONSE REGULATOR receiver - - - 1.27e-196 619.0
HFD3_k127_280262_10 SMART Rhodanese domain protein - - - 0.00000000000000002919 89.0
HFD3_k127_280262_11 ThiS family K03636 - - 0.00000000000001631 77.0
HFD3_k127_280262_2 AMP-binding protein K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008451 586.0
HFD3_k127_280262_3 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 499.0
HFD3_k127_280262_4 Bacterial protein of unknown function (DUF899) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 450.0
HFD3_k127_280262_5 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 406.0
HFD3_k127_280262_6 [2Fe-2S] binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006927 275.0
HFD3_k127_280262_7 MaoC like domain - - - 0.00000000000000000000000000000000003014 139.0
HFD3_k127_280262_8 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000008808 149.0
HFD3_k127_280262_9 Endoribonuclease L-PSP - - - 0.00000000000000000000000000001075 137.0
HFD3_k127_2825780_0 biosynthesis protein E K06139 GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0018130,GO:0018189,GO:0018193,GO:0018212,GO:0019538,GO:0019752,GO:0034641,GO:0036211,GO:0042180,GO:0042181,GO:0042364,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072350,GO:0072351,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901661,GO:1901663 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 492.0
HFD3_k127_2825780_1 May be involved in the transport of PQQ or its precursor to the periplasm K06136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 387.0
HFD3_k127_2825780_2 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004141 348.0
HFD3_k127_2825780_3 PQQ-dependent catabolism-associated beta-propeller protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008614 277.0
HFD3_k127_2825780_4 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001087 274.0
HFD3_k127_2825780_5 Predicted permease K07089 - - 0.00000000000000000000000000000000000002211 163.0
HFD3_k127_2825780_6 amino acid transport K02030 - - 0.00000000000000000000000000003398 136.0
HFD3_k127_2825780_7 methylamine metabolic process K03885,K16937 - 1.6.99.3,1.8.5.2 0.0000000000000000000000001503 112.0
HFD3_k127_2825780_8 biosynthesis protein E K06139 GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0018130,GO:0018189,GO:0018193,GO:0018212,GO:0019538,GO:0019752,GO:0034641,GO:0036211,GO:0042180,GO:0042181,GO:0042364,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072350,GO:0072351,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901661,GO:1901663 - 0.000000000000101 78.0
HFD3_k127_2830659_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 9.944e-295 913.0
HFD3_k127_2830659_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.49e-273 854.0
HFD3_k127_2830659_10 Aminoacyl-tRNA editing domain K19055 - - 0.0000000000000000000000000000102 125.0
HFD3_k127_2830659_11 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.000000000000000000000006296 115.0
HFD3_k127_2830659_12 IMP dehydrogenase activity K04767 - - 0.0000000000000000000000119 108.0
HFD3_k127_2830659_13 Domain in cystathionine beta-synthase and other proteins. K04767 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 - 0.00000000000000000004278 98.0
HFD3_k127_2830659_14 Phosphopantetheine attachment site - - - 0.000000000000003732 88.0
HFD3_k127_2830659_15 THUMP domain K06963 - - 0.00000000053 72.0
HFD3_k127_2830659_16 Uncharacterized conserved protein (DUF2267) - - - 0.0001724 51.0
HFD3_k127_2830659_2 S-acyltransferase activity K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 458.0
HFD3_k127_2830659_3 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00162,K11381 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003968 468.0
HFD3_k127_2830659_4 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00161,K00162,K11381,K21416 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 436.0
HFD3_k127_2830659_5 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007625 413.0
HFD3_k127_2830659_6 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 305.0
HFD3_k127_2830659_7 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000002949 265.0
HFD3_k127_2830659_8 Haem-binding domain - - - 0.000000000000000000000000000000000000000000000001382 179.0
HFD3_k127_2830659_9 redox protein, regulator of disulfide bond formation - - - 0.00000000000000000000000000000005578 129.0
HFD3_k127_283535_0 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006847 282.0
HFD3_k127_283535_1 Transcriptional Regulator, AraC family - - - 0.00000000000000000000000000000000000000000000005654 171.0
HFD3_k127_283535_2 Protein of unknown function, DUF417 - - - 0.00000000000000000000000000000000000000000001859 167.0
HFD3_k127_283709_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007353 521.0
HFD3_k127_283709_1 Fe-S oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 372.0
HFD3_k127_283709_10 Pfam:DUF59 - - - 0.00000000000000000000706 107.0
HFD3_k127_283709_11 Universal stress protein family - - - 0.0000000000000000001145 95.0
HFD3_k127_283709_12 cyclic nucleotide-binding - - - 0.0000000000000003375 84.0
HFD3_k127_283709_13 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.0006811 46.0
HFD3_k127_283709_14 Cbs domain K04767 - - 0.00073 44.0
HFD3_k127_283709_2 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 361.0
HFD3_k127_283709_3 Belongs to the heme-copper respiratory oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001169 264.0
HFD3_k127_283709_4 Domain of unknown function (DUF1858) - - - 0.000000000000000000000000000000000000000000001224 179.0
HFD3_k127_283709_5 COG3005 Nitrate TMAO K15876 - - 0.000000000000000000000000000000000000000001003 160.0
HFD3_k127_283709_6 PFAM Cyclic nucleotide-binding K10914,K21564 - - 0.000000000000000000000000000000001019 151.0
HFD3_k127_283709_7 Cytochrome C and Quinol oxidase polypeptide I - - - 0.000000000000000000000000000000004107 133.0
HFD3_k127_283709_8 PFAM CBS domain K04767 - - 0.0000000000000000000000000000001602 134.0
HFD3_k127_283709_9 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.00000000000000000000006292 107.0
HFD3_k127_288647_0 Amidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 620.0
HFD3_k127_288647_1 Family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008335 316.0
HFD3_k127_288647_10 AraC-like ligand binding domain - - - 0.0000000000000000000000000000000000000001354 156.0
HFD3_k127_288647_11 Protein of unknown function DUF86 - - - 0.000000000000000000000000000000000002597 147.0
HFD3_k127_288647_12 Nucleotidyltransferase domain - - - 0.00000000000000000000000000008007 121.0
HFD3_k127_288647_13 N-acyl-D-aspartate D-glutamate deacylase K01465,K06015 - 3.5.1.81,3.5.2.3 0.00000000000004053 77.0
HFD3_k127_288647_14 amine dehydrogenase activity K01751,K01754 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008838,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575 4.3.1.15,4.3.1.19 0.0007559 53.0
HFD3_k127_288647_2 BFD-like [2Fe-2S] binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009083 305.0
HFD3_k127_288647_3 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001806 284.0
HFD3_k127_288647_4 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000002104 260.0
HFD3_k127_288647_5 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000658 266.0
HFD3_k127_288647_6 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000439 241.0
HFD3_k127_288647_7 NAD(P)-binding Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000007092 233.0
HFD3_k127_288647_8 2OG-Fe(II) oxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000004816 194.0
HFD3_k127_288647_9 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000002616 193.0
HFD3_k127_2906357_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 414.0
HFD3_k127_2906357_1 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 388.0
HFD3_k127_2906357_10 Poly A polymerase head domain K00970,K00974,K07276,K19545 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000003828 278.0
HFD3_k127_2906357_11 COG1921 Selenocysteine synthase seryl-tRNASer selenium transferase K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000007197 261.0
HFD3_k127_2906357_12 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003535 257.0
HFD3_k127_2906357_13 helix_turn _helix lactose operon repressor K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005655 250.0
HFD3_k127_2906357_14 Pfam:KaiC - - - 0.000000000000000000000000000000000000000000000000000000000000004329 227.0
HFD3_k127_2906357_15 FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000002981 211.0
HFD3_k127_2906357_16 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000003161 184.0
HFD3_k127_2906357_17 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000004869 175.0
HFD3_k127_2906357_18 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.000000000000000000000000000000000000000000001394 172.0
HFD3_k127_2906357_19 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000005824 83.0
HFD3_k127_2906357_2 Extracellular liganD-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 372.0
HFD3_k127_2906357_20 - - - - 0.00000000000000008775 91.0
HFD3_k127_2906357_21 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.000000000001769 74.0
HFD3_k127_2906357_22 - - - - 0.000007822 48.0
HFD3_k127_2906357_23 Polysaccharide deacetylase - - - 0.000564 51.0
HFD3_k127_2906357_24 Adenylate and Guanylate cyclase catalytic domain - - - 0.0006693 43.0
HFD3_k127_2906357_3 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 323.0
HFD3_k127_2906357_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 306.0
HFD3_k127_2906357_5 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009511 306.0
HFD3_k127_2906357_6 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000562 315.0
HFD3_k127_2906357_7 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005723 292.0
HFD3_k127_2906357_8 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002521 297.0
HFD3_k127_2906357_9 Class II Aldolase and Adducin N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006028 285.0
HFD3_k127_2919078_0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 340.0
HFD3_k127_2919078_1 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 331.0
HFD3_k127_2919078_10 Adenylyl- / guanylyl cyclase, catalytic domain K01768,K07315 - 3.1.3.3,4.6.1.1 0.0000000000000000000000000000000000000000000000000000007078 198.0
HFD3_k127_2919078_11 CDP-diacylglycerol pyrophosphatase K01521 - 3.6.1.26 0.00000000000000000000000000000000000000000000000003415 190.0
HFD3_k127_2919078_12 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.00000000000000000000000000000000000000000000002596 176.0
HFD3_k127_2919078_13 - - - - 0.00000000000000000000000000000000000003488 148.0
HFD3_k127_2919078_14 3-demethylubiquinone-9 3-O-methyltransferase activity K20444 - - 0.000000000000000000000000000000000001148 150.0
HFD3_k127_2919078_15 Predicted membrane protein (DUF2079) - - - 0.00000000000000000000000000000007719 144.0
HFD3_k127_2919078_16 - - - - 0.000000005457 69.0
HFD3_k127_2919078_2 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 341.0
HFD3_k127_2919078_3 Transketolase, central region K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 304.0
HFD3_k127_2919078_4 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001192 283.0
HFD3_k127_2919078_5 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000001094 273.0
HFD3_k127_2919078_6 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000702 254.0
HFD3_k127_2919078_7 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.0000000000000000000000000000000000000000000000000000000000000000007802 236.0
HFD3_k127_2919078_8 domain protein K01992,K06994 - - 0.000000000000000000000000000000000000000000000000000000000000009928 228.0
HFD3_k127_2919078_9 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000008736 218.0
HFD3_k127_2919138_0 Belongs to the TPP enzyme family K01576 - 4.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006391 501.0
HFD3_k127_2919138_1 Nitrile hydratase, alpha chain K01721 - 4.2.1.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 370.0
HFD3_k127_2919138_2 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002598 259.0
HFD3_k127_2919138_3 ferredoxin-thioredoxin reductase activity K17892 GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015979,GO:0016491,GO:0016730,GO:0022900,GO:0030385,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114 1.8.7.2 0.0000000000000000000000000000000000000000000000000000001007 198.0
HFD3_k127_2919138_4 NHase catalyzes the hydration of various nitrile compounds to the corresponding amides K20807 - 4.2.1.84 0.000000000000000000000000000000000000000000001071 178.0
HFD3_k127_2919138_5 Glutaredoxin - - - 0.000000000002093 68.0
HFD3_k127_291991_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009187 594.0
HFD3_k127_291991_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000002664 186.0
HFD3_k127_291991_2 protein kinase activity - - - 0.00000000000000000000000000000000000001693 150.0
HFD3_k127_2932836_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0 1133.0
HFD3_k127_2932836_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 4.443e-224 711.0
HFD3_k127_2932836_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007091 443.0
HFD3_k127_2932836_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008345 303.0
HFD3_k127_2932836_4 Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001613 292.0
HFD3_k127_2932836_5 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004828 280.0
HFD3_k127_2932836_6 OsmC-like protein - - - 0.000000000000000000000000000000000000000000000000000000000002802 214.0
HFD3_k127_2932836_7 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000108 119.0
HFD3_k127_2939644_0 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 290.0
HFD3_k127_2939644_1 PFAM ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004256 278.0
HFD3_k127_2939644_2 Periplasmic binding protein domain - - - 0.00006777 50.0
HFD3_k127_2949552_0 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 578.0
HFD3_k127_2949552_1 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 531.0
HFD3_k127_2949552_2 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.00000000000000000000000002335 112.0
HFD3_k127_2949552_3 COG0457 FOG TPR repeat - - - 0.00000000000000101 91.0
HFD3_k127_2949552_4 Tetratricopeptide repeat - - - 0.00000832 59.0
HFD3_k127_2972947_0 Predicted Permease Membrane Region - - - 1.089e-223 703.0
HFD3_k127_2972947_1 Sodium/calcium exchanger protein K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004153 565.0
HFD3_k127_2972947_2 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007767 398.0
HFD3_k127_2972947_3 Ion channel - - - 0.00000000000000000000000002486 113.0
HFD3_k127_3027725_0 Proline dehydrogenase K13821 - 1.2.1.88,1.5.5.2 0.0 1109.0
HFD3_k127_3027725_1 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 4.349e-282 881.0
HFD3_k127_3027725_10 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000001265 209.0
HFD3_k127_3027725_11 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000006307 198.0
HFD3_k127_3027725_12 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000008672 193.0
HFD3_k127_3027725_13 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000000000000000000001864 180.0
HFD3_k127_3027725_14 DsbA oxidoreductase - - - 0.00000000000000000000000000000000000000000000003498 175.0
HFD3_k127_3027725_15 Predicted membrane protein (DUF2231) - - - 0.000000000000000000000000000000001676 137.0
HFD3_k127_3027725_16 Transglycosylase associated protein - - - 0.000000000000000000000004091 117.0
HFD3_k127_3027725_17 - - - - 0.00000000001984 66.0
HFD3_k127_3027725_18 Putative peptidoglycan binding domain - - - 0.00000002747 58.0
HFD3_k127_3027725_19 - - - - 0.0000006071 62.0
HFD3_k127_3027725_20 - - - - 0.00001659 55.0
HFD3_k127_3027725_21 Evidence 4 Homologs of previously reported genes of - - - 0.00002284 57.0
HFD3_k127_3027725_3 COG0402 Cytosine deaminase and related metal-dependent hydrolases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 507.0
HFD3_k127_3027725_4 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 422.0
HFD3_k127_3027725_5 drug resistance transporter, EmrB QacA subfamily K03446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 376.0
HFD3_k127_3027725_6 Luciferase-like monooxygenase K15510 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.98.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003746 312.0
HFD3_k127_3027725_7 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005027 302.0
HFD3_k127_3027725_8 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002341 285.0
HFD3_k127_3027725_9 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000003597 222.0
HFD3_k127_3109463_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 8.489e-213 682.0
HFD3_k127_3109463_1 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 563.0
HFD3_k127_3109463_10 PFAM extracellular solute-binding protein family 1 K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 370.0
HFD3_k127_3109463_11 DNA helicase K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 323.0
HFD3_k127_3109463_12 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004485 309.0
HFD3_k127_3109463_13 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 302.0
HFD3_k127_3109463_14 Aldolase/RraA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007168 259.0
HFD3_k127_3109463_15 3-oxoacyl-ACP reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000002064 267.0
HFD3_k127_3109463_16 COG1838 Tartrate dehydratase beta subunit Fumarate hydratase class I, C-terminal domain K03780 - 4.2.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000436 258.0
HFD3_k127_3109463_17 Cytochrome C assembly protein K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.00000000000000000000000000000000000000000000000000000000000000000003101 238.0
HFD3_k127_3109463_18 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000005084 226.0
HFD3_k127_3109463_19 Thioredoxin-like K02199,K03671 - - 0.0000000000000000000000000000000000000000000000000000000008995 228.0
HFD3_k127_3109463_2 PFAM Cytochrome C assembly protein K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006362 571.0
HFD3_k127_3109463_20 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000000000004605 198.0
HFD3_k127_3109463_21 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.00000000000000000000000000000000000000008439 168.0
HFD3_k127_3109463_22 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000004132 141.0
HFD3_k127_3109463_23 subunit of a heme lyase K02198,K02200 - - 0.00000000000000000000000000004269 122.0
HFD3_k127_3109463_24 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000001886 119.0
HFD3_k127_3109463_25 COG0457 FOG TPR repeat - - - 0.000000000000000000000000001413 129.0
HFD3_k127_3109463_26 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000000004253 109.0
HFD3_k127_3109463_27 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000006691 110.0
HFD3_k127_3109463_28 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000001886 106.0
HFD3_k127_3109463_29 Ribosomal L32p protein family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.0000000000000000003599 89.0
HFD3_k127_3109463_3 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 501.0
HFD3_k127_3109463_30 Protein of unknown function (DUF1706) - - - 0.00000000005601 73.0
HFD3_k127_3109463_31 SMART Tetratricopeptide - - - 0.0003481 53.0
HFD3_k127_3109463_4 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 494.0
HFD3_k127_3109463_5 Fe-S type, tartrate fumarate subfamily, alpha subunit K03779 - 4.2.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 458.0
HFD3_k127_3109463_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005611 392.0
HFD3_k127_3109463_7 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 376.0
HFD3_k127_3109463_8 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 366.0
HFD3_k127_3109463_9 Belongs to the peptidase M48B family K03799 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 359.0
HFD3_k127_3116693_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 617.0
HFD3_k127_3116693_1 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005984 383.0
HFD3_k127_3116693_2 Protein of unknown function (DUF1847) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 317.0
HFD3_k127_3116693_3 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.0000000000000000000000000000000000000000000000000000000000003128 222.0
HFD3_k127_3116693_4 - - - - 0.0000003717 61.0
HFD3_k127_3120722_0 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 565.0
HFD3_k127_3120722_1 Pfam:DUF1446 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008352 510.0
HFD3_k127_3120722_10 pfam abc K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002037 268.0
HFD3_k127_3120722_11 Receptor family ligand binding region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002379 271.0
HFD3_k127_3120722_12 Binding-protein-dependent transport system inner membrane component K02025,K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001664 253.0
HFD3_k127_3120722_13 KR domain - - - 0.0000000000000000000000000000000000000000000003784 177.0
HFD3_k127_3120722_14 ABC-type sugar transport system, periplasmic component K02027 - - 0.00000000000000000000000000000006392 141.0
HFD3_k127_3120722_15 Domain of unknown function (DUF4387) - - - 0.000000000000000000000000002688 115.0
HFD3_k127_3120722_16 Cupin domain - - - 0.000000000001497 75.0
HFD3_k127_3120722_17 - - - - 0.00000000001049 68.0
HFD3_k127_3120722_18 Metallo-beta-lactamase superfamily - - - 0.00000000318 58.0
HFD3_k127_3120722_2 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 408.0
HFD3_k127_3120722_3 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 394.0
HFD3_k127_3120722_4 C-C_Bond_Lyase of the TIM-Barrel fold K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 342.0
HFD3_k127_3120722_5 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006384 334.0
HFD3_k127_3120722_6 ABC-type sugar transport system, permease component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 304.0
HFD3_k127_3120722_7 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 291.0
HFD3_k127_3120722_8 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008335 282.0
HFD3_k127_3120722_9 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001476 276.0
HFD3_k127_3147244_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1310.0
HFD3_k127_3147244_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007428 352.0
HFD3_k127_3147244_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 324.0
HFD3_k127_3147244_3 Berberine and berberine like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004658 294.0
HFD3_k127_3147244_4 hydrolase, CocE NonD family K06978 - - 0.00000000000000000002004 93.0
HFD3_k127_3147244_5 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000007452 84.0
HFD3_k127_3147244_6 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000005491 63.0
HFD3_k127_3147244_7 Adenylate cyclase - - - 0.000008367 57.0
HFD3_k127_3147446_0 NADH-quinone oxidoreductase chain L K00341 - 1.6.5.3 6.195e-195 635.0
HFD3_k127_3147446_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 6.502e-195 620.0
HFD3_k127_3147446_10 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000000000003495 199.0
HFD3_k127_3147446_11 Fibronectin type 3 domain K12685,K16785,K16786,K16787 - - 0.00000000000000000000000000000000000000000000002511 182.0
HFD3_k127_3147446_12 Removes 5-oxoproline from various penultimate amino acid residues except L-proline K01304 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:1901564 3.4.19.3 0.00000000000000000000000000000000000000000000005022 187.0
HFD3_k127_3147446_13 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000005231 154.0
HFD3_k127_3147446_14 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000001415 151.0
HFD3_k127_3147446_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 446.0
HFD3_k127_3147446_3 Chalcone and stilbene synthases, C-terminal domain K16424 GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 2.3.1.246 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009218 384.0
HFD3_k127_3147446_4 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005632 366.0
HFD3_k127_3147446_5 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 358.0
HFD3_k127_3147446_6 COGs COG0647 sugar phosphatase of the HAD superfamily K01101,K02566 - 3.1.3.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009265 291.0
HFD3_k127_3147446_7 PFAM Peptidase M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001453 282.0
HFD3_k127_3147446_8 TIGRFAM geranylgeranyl reductase K21401 - 1.3.99.38 0.00000000000000000000000000000000000000000000000000000000000000000000000008815 271.0
HFD3_k127_3147446_9 Bacterial transferase hexapeptide (six repeats) - GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008270,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043168,GO:0043169,GO:0043199,GO:0046872,GO:0046914,GO:0050897,GO:0071890,GO:1901681 - 0.000000000000000000000000000000000000000000000000000000000000000000003587 242.0
HFD3_k127_3154220_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 1.236e-273 860.0
HFD3_k127_3154220_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.239e-213 675.0
HFD3_k127_3154220_2 F420-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000218 261.0
HFD3_k127_3154220_3 SMP-30/Gluconolaconase/LRE-like region - - - 0.000005312 50.0
HFD3_k127_3161414_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 1.529e-240 750.0
HFD3_k127_3161414_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 4.173e-204 651.0
HFD3_k127_3161414_10 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000002795 209.0
HFD3_k127_3161414_11 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000005301 171.0
HFD3_k127_3161414_12 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000002514 135.0
HFD3_k127_3161414_13 Protein of unknown function (DUF983) - - - 0.000000000000000000000000001284 117.0
HFD3_k127_3161414_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005077 489.0
HFD3_k127_3161414_3 Amidase K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 444.0
HFD3_k127_3161414_4 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 373.0
HFD3_k127_3161414_5 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000473 327.0
HFD3_k127_3161414_6 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000496 278.0
HFD3_k127_3161414_7 wide pore channel activity K07267 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002368 282.0
HFD3_k127_3161414_8 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004885 265.0
HFD3_k127_3161414_9 6-phosphogluconolactonase K00851,K01057 - 2.7.1.12,3.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000009739 254.0
HFD3_k127_3163215_0 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007485 439.0
HFD3_k127_3256103_0 4-hydroxyphenylacetate K00483 - 1.14.14.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 515.0
HFD3_k127_3256103_1 peptidase dimerisation domain protein K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004039 472.0
HFD3_k127_3256103_10 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000003079 235.0
HFD3_k127_3256103_11 metal-dependent hydrolase of the TIM-barrel fold K07046 - - 0.0000000000000000000000000000000000000000000000000000000002799 214.0
HFD3_k127_3256103_12 Acyl-CoA thioesterase K10805 - - 0.000000000000000000000000000000000000000005583 158.0
HFD3_k127_3256103_13 Amidohydrolase family - - - 0.0000000000000000000000001276 112.0
HFD3_k127_3256103_14 amidohydrolase - - - 0.0000000001914 63.0
HFD3_k127_3256103_2 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 390.0
HFD3_k127_3256103_3 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 356.0
HFD3_k127_3256103_4 Receptor family ligand binding region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 304.0
HFD3_k127_3256103_5 PFAM ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006562 282.0
HFD3_k127_3256103_6 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009956 284.0
HFD3_k127_3256103_7 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001631 274.0
HFD3_k127_3256103_8 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000001214 255.0
HFD3_k127_3256103_9 amidohydrolase K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000004277 262.0
HFD3_k127_3290780_0 PFAM Binding-protein-dependent transport system inner membrane component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 545.0
HFD3_k127_3290780_1 DNA helicase K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 412.0
HFD3_k127_3290780_10 Cupin domain - - - 0.000000002604 70.0
HFD3_k127_3290780_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02052 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 386.0
HFD3_k127_3290780_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000005134 160.0
HFD3_k127_3290780_4 HAD-superfamily hydrolase, subfamily IIB - - - 0.0000000000000000000000000000000000007324 149.0
HFD3_k127_3290780_5 hydroperoxide reductase activity - - - 0.00000000000000000000000000000007229 128.0
HFD3_k127_3290780_6 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000002049 116.0
HFD3_k127_3290780_7 Cytidylate kinase-like family - - - 0.00000000000000000000000002602 120.0
HFD3_k127_3290780_8 Xylose isomerase-like TIM barrel K06606 - 5.3.99.11 0.000000000000000000008173 105.0
HFD3_k127_3290780_9 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000001468 83.0
HFD3_k127_3324686_0 aldehyde-lyase activity K01621 - 4.1.2.22,4.1.2.9 5e-323 991.0
HFD3_k127_3324686_1 Fructose-bisphosphate aldolase class-I K01623 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 434.0
HFD3_k127_3324686_2 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.0001032 45.0
HFD3_k127_3336251_0 transmembrane transporter activity K03296 - - 9.4e-323 1019.0
HFD3_k127_3336251_1 Multicopper oxidase K22348 - 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008539 568.0
HFD3_k127_3336251_2 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004651 316.0
HFD3_k127_3336251_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000002913 252.0
HFD3_k127_3336251_4 CHASE2 K01768,K01769 - 4.6.1.1,4.6.1.2 0.00000000000000000000000000000000000001298 154.0
HFD3_k127_3336251_5 PFAM Outer membrane efflux protein K03287 - - 0.00000000000000000000001692 115.0
HFD3_k127_3336251_6 Cytochrome c - - - 0.000000000004702 78.0
HFD3_k127_3336251_9 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.0002636 51.0
HFD3_k127_3357327_0 Luciferase-like monooxygenase - - - 2.399e-207 649.0
HFD3_k127_3357327_1 PFAM 4-hydroxyphenylacetate 3-hydroxylase K00483,K16901 - 1.14.14.8,1.14.14.9 7.254e-200 636.0
HFD3_k127_3357327_10 AAA ATPase forming ring-shaped complexes K13527 GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 316.0
HFD3_k127_3357327_11 Proteasome subunit K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019774,GO:0019899,GO:0019941,GO:0030163,GO:0032991,GO:0035375,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 310.0
HFD3_k127_3357327_12 Proteasome subunit K03432 - 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 289.0
HFD3_k127_3357327_13 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001287 301.0
HFD3_k127_3357327_14 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004546 291.0
HFD3_k127_3357327_15 oxidation-reduction process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005599 248.0
HFD3_k127_3357327_16 glycolate biosynthetic process K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000463 239.0
HFD3_k127_3357327_17 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000006849 227.0
HFD3_k127_3357327_18 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000002552 211.0
HFD3_k127_3357327_19 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000001056 219.0
HFD3_k127_3357327_2 Pup-ligase protein K20814 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.119 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 597.0
HFD3_k127_3357327_20 MarR family transcriptional regulator - - - 0.00000000000000000000000000000000000000000000003218 175.0
HFD3_k127_3357327_21 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000001545 168.0
HFD3_k127_3357327_22 Cupin domain - - - 0.00000000000000000000000000000000000001226 167.0
HFD3_k127_3357327_23 DinB superfamily - - - 0.00000000000002454 86.0
HFD3_k127_3357327_24 COG0747 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.00000000000003564 78.0
HFD3_k127_3357327_25 Antibiotic biosynthesis monooxygenase - - - 0.000000000009457 70.0
HFD3_k127_3357327_26 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000008289 62.0
HFD3_k127_3357327_3 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K13571 GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 6.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005153 582.0
HFD3_k127_3357327_4 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 441.0
HFD3_k127_3357327_5 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007108 392.0
HFD3_k127_3357327_6 Belongs to the amidase family K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 394.0
HFD3_k127_3357327_7 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 357.0
HFD3_k127_3357327_8 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 353.0
HFD3_k127_3357327_9 alcohol dehydrogenase K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000668 342.0
HFD3_k127_33648_0 Belongs to the IlvD Edd family K22396 - 4.2.1.82 2.199e-313 971.0
HFD3_k127_33648_1 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009703 563.0
HFD3_k127_33648_2 AIR synthase related protein, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 543.0
HFD3_k127_33648_3 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000001769 181.0
HFD3_k127_3386016_0 COG3209 Rhs family protein - - - 3.492e-226 748.0
HFD3_k127_3386016_1 Amidohydrolase family - - - 3.138e-200 639.0
HFD3_k127_3386016_2 COG1062 Zn-dependent alcohol dehydrogenases, class III K00001,K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009907 322.0
HFD3_k127_3386016_3 Catalytic LigB subunit of aromatic ring-opening dioxygenase K04101 - 1.13.11.8 0.0000000000000000000000000000000000000000000000000000000000000000000004358 252.0
HFD3_k127_3386016_4 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000006348 256.0
HFD3_k127_3386016_5 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000000000000000000000000000000451 144.0
HFD3_k127_3386016_6 Aromatic-ring-opening dioxygenase LigAB, LigA subunit - - - 0.00000000000006882 76.0
HFD3_k127_3386016_7 OsmC-like protein - - - 0.0000000000007689 79.0
HFD3_k127_3386016_8 Cupin 2, conserved barrel domain protein - - - 0.000000000001533 73.0
HFD3_k127_3390698_0 Belongs to the UbiD family K03182 - 4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 608.0
HFD3_k127_3390698_1 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 369.0
HFD3_k127_3390698_10 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000001232 93.0
HFD3_k127_3390698_11 Luciferase-like monooxygenase - - - 0.000000000000867 70.0
HFD3_k127_3390698_12 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000003769 61.0
HFD3_k127_3390698_2 COGs COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 346.0
HFD3_k127_3390698_3 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004192 319.0
HFD3_k127_3390698_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000002074 214.0
HFD3_k127_3390698_5 Putative glycosyl hydrolase domain - - - 0.0000000000000000000000000000000000000000000000000000000002513 216.0
HFD3_k127_3390698_6 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000344 181.0
HFD3_k127_3390698_7 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000008086 147.0
HFD3_k127_3390698_8 Predicted permease - - - 0.00000000000000000000000006811 115.0
HFD3_k127_3390698_9 Helix-turn-helix domain - - - 0.00000000000000000001059 95.0
HFD3_k127_3409256_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 8.467e-316 984.0
HFD3_k127_3409256_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 9.025e-222 700.0
HFD3_k127_3409256_10 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000008478 248.0
HFD3_k127_3409256_11 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000003244 216.0
HFD3_k127_3409256_12 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.0000000000000000000000000000000005081 151.0
HFD3_k127_3409256_13 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000001448 136.0
HFD3_k127_3409256_14 Evidence 5 No homology to any previously reported sequences K03643 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - 0.0000000000000000000004443 104.0
HFD3_k127_3409256_15 TIGRFAM lipopolysaccharide transport periplasmic protein LptA K09774 - - 0.0000000000000000001895 100.0
HFD3_k127_3409256_16 Lipopolysaccharide-assembly, LptC-related - - - 0.000000000001075 76.0
HFD3_k127_3409256_17 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000001521 71.0
HFD3_k127_3409256_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 571.0
HFD3_k127_3409256_3 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 422.0
HFD3_k127_3409256_4 RNA polymerase sigma-54 factor K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 405.0
HFD3_k127_3409256_5 Belongs to the SIS family. GutQ KpsF subfamily K01627,K03281,K06041 - 2.5.1.55,5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009496 370.0
HFD3_k127_3409256_6 PFAM DAHP synthetase I KDSA K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 362.0
HFD3_k127_3409256_7 lipopolysaccharide transport protein B ATP-binding component of ABC superfamily K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 334.0
HFD3_k127_3409256_8 P-loop ATPase protein family K06958 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003392 326.0
HFD3_k127_3409256_9 Phage integrase, N-terminal SAM-like domain K03733,K04763 GO:0000150,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009314,GO:0009628,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0071139,GO:0071704,GO:0090304,GO:0140097,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 291.0
HFD3_k127_3410128_0 PFAM phospholipase Carboxylesterase K06999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 301.0
HFD3_k127_3410128_1 PFAM Integrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 306.0
HFD3_k127_3451853_0 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008787 329.0
HFD3_k127_3451853_1 Belongs to the peptidase S51 family K05995 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.13.21 0.00000000000000000000000000000000000000004121 165.0
HFD3_k127_3451853_2 Belongs to the HAD-like hydrolase superfamily K01101 - 3.1.3.41 0.0000000000000001013 83.0
HFD3_k127_3463606_0 Hemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002522 268.0
HFD3_k127_3478637_0 efflux transmembrane transporter activity - - - 2.846e-277 886.0
HFD3_k127_3478637_1 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000000000005289 171.0
HFD3_k127_3478637_2 RibD C-terminal domain - - - 0.00000000000000000004039 98.0
HFD3_k127_3478637_3 beta-galactosidase activity K15855 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005576,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044238,GO:0071704,GO:1901575 3.2.1.165 0.000000002715 58.0
HFD3_k127_3478904_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 332.0
HFD3_k127_3478904_1 Resolvase, N terminal domain - - - 0.00000007723 56.0
HFD3_k127_3481237_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 4.723e-284 882.0
HFD3_k127_3481237_1 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 497.0
HFD3_k127_3481237_10 SelR domain K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000007131 227.0
HFD3_k127_3481237_11 Enoyl-(Acyl carrier protein) reductase K00059,K10780 - 1.1.1.100,1.3.1.104 0.0000000000000000000000000000000001337 137.0
HFD3_k127_3481237_12 Alpha beta hydrolase - - - 0.00000000000000000000000000000002688 144.0
HFD3_k127_3481237_13 - - - - 0.0000000000000184 76.0
HFD3_k127_3481237_14 Major Facilitator Superfamily - - - 0.0000000000007335 76.0
HFD3_k127_3481237_15 Major Facilitator Superfamily - - - 0.00004217 53.0
HFD3_k127_3481237_2 III protein, CoA-transferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 488.0
HFD3_k127_3481237_3 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 466.0
HFD3_k127_3481237_4 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 458.0
HFD3_k127_3481237_5 Protein of unknown function (DUF1624) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004255 363.0
HFD3_k127_3481237_6 Isochorismatase family K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 332.0
HFD3_k127_3481237_7 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 326.0
HFD3_k127_3481237_8 Putative FMN-binding domain K07734 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001019 271.0
HFD3_k127_3481237_9 Nitronate monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002969 268.0
HFD3_k127_3543710_0 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000357 310.0
HFD3_k127_3543710_1 Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 294.0
HFD3_k127_3543710_2 Domain of unknown function (DUF1932) - - - 0.00000000000000000000000000000000000000000000000000000003007 214.0
HFD3_k127_3543710_3 Extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000005098 178.0
HFD3_k127_3543710_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000009015 61.0
HFD3_k127_3548681_0 CoA-transferase family III K01796 - 5.1.99.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 502.0
HFD3_k127_3548681_1 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 485.0
HFD3_k127_3548681_2 metal-dependent hydrolase of the TIM-barrel fold K07046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006493 457.0
HFD3_k127_3548681_3 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 353.0
HFD3_k127_3548681_4 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006401 276.0
HFD3_k127_3548681_5 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000001099 231.0
HFD3_k127_3548681_6 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000002704 215.0
HFD3_k127_3548681_7 Redoxin K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000003509 209.0
HFD3_k127_3548681_8 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000009567 150.0
HFD3_k127_3548681_9 cyclic nucleotide binding K10914 - - 0.000000000000000000004673 102.0
HFD3_k127_3556268_0 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 319.0
HFD3_k127_3556268_1 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000001465 220.0
HFD3_k127_3556268_2 YCII-related domain - - - 0.0000000000000000000000000000000000000001188 154.0
HFD3_k127_3556268_3 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000258 90.0
HFD3_k127_3604098_0 Glycine cleavage system P-protein K00283 - 1.4.4.2 4.046e-198 628.0
HFD3_k127_3604098_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007094 481.0
HFD3_k127_3604098_10 Metallo-beta-lactamase superfamily K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006090,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019184,GO:0019752,GO:0031974,GO:0032787,GO:0034641,GO:0042398,GO:0043043,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0051186,GO:0051188,GO:0070013,GO:0071704,GO:1901564,GO:1901566,GO:1901576 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000001634 264.0
HFD3_k127_3604098_11 Domain of unknown function (DUF4340) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001125 258.0
HFD3_k127_3604098_12 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000004372 264.0
HFD3_k127_3604098_13 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 - - 0.000000000000000000000000000000000000000000000004668 178.0
HFD3_k127_3604098_14 PFAM Biotin lipoate A B protein ligase family K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000001809 176.0
HFD3_k127_3604098_15 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 - - 0.0000000000000000000000000000000000000008183 163.0
HFD3_k127_3604098_16 major facilitator superfamily - - - 0.000000000000000000000000000000000000002188 163.0
HFD3_k127_3604098_17 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000003362 156.0
HFD3_k127_3604098_18 NUDIX domain - - - 0.000000000000000000000000000004721 135.0
HFD3_k127_3604098_19 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000009765 117.0
HFD3_k127_3604098_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 400.0
HFD3_k127_3604098_20 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051,K15576,K22067 - - 0.00005234 55.0
HFD3_k127_3604098_21 Thioesterase superfamily - - - 0.0001998 55.0
HFD3_k127_3604098_3 Sugar (and other) transporter K03446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004583 395.0
HFD3_k127_3604098_4 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008371 381.0
HFD3_k127_3604098_5 Belongs to the D-glutamate cyclase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008443 364.0
HFD3_k127_3604098_6 ABC-type uncharacterized transport system K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007321 361.0
HFD3_k127_3604098_7 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09697 - 3.6.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 347.0
HFD3_k127_3604098_8 Allophanate hydrolase subunit 2 K06350 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003249 273.0
HFD3_k127_3604098_9 DNA polymerase alpha chain like domain K07053,K20859 - 3.1.3.97,3.1.4.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000008507 266.0
HFD3_k127_3650896_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1297.0
HFD3_k127_3650896_1 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000704 508.0
HFD3_k127_3650896_2 Domain of unknown function (DUF4395) - - - 0.00000000000000000000000000000000000000000000000000000000000000000429 232.0
HFD3_k127_3650896_3 Bacterial-like globin K06886 - - 0.000000000000000000000000000000000000000000000000000000126 198.0
HFD3_k127_3650896_4 Arsenical resistance operon trans-acting repressor arsD - - - 0.000000000000000000004524 96.0
HFD3_k127_3650896_5 Thioredoxin domain - - - 0.0000000000000003521 93.0
HFD3_k127_3650896_6 Predicted permease K07089 - - 0.0000001722 53.0
HFD3_k127_3666576_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688,K18786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.321 0.0 1333.0
HFD3_k127_3666576_1 PFAM ABC transporter K02471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007939 625.0
HFD3_k127_3666576_2 PFAM ABC transporter, transmembrane region K06147,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 404.0
HFD3_k127_3666576_3 Glycosyl hydrolase 36 superfamily, catalytic domain - - - 0.0000000000000000000000000002516 123.0
HFD3_k127_3666576_4 Glycosyl hydrolase 36 superfamily, catalytic domain K13688,K18786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.321 0.000000000000000000000000003575 122.0
HFD3_k127_3666576_5 Transposase domain (DUF772) - - - 0.000000000000000000000002726 108.0
HFD3_k127_3666576_6 Integrin alpha (beta-propellor repeats). - - - 0.00000000000000001698 91.0
HFD3_k127_3666576_7 translation initiation factor activity K06996 - - 0.00000000007862 68.0
HFD3_k127_3667539_0 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000006551 230.0
HFD3_k127_3667539_1 Pas domain - - - 0.00000000000000000000000000000000000003035 156.0
HFD3_k127_3673163_0 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008888 252.0
HFD3_k127_3673163_1 AAA ATPase domain - - - 0.000000000000003943 83.0
HFD3_k127_3673163_2 Phage integrase family - - - 0.00000008048 57.0
HFD3_k127_3727864_0 Branched-chain amino acid transport system / permease component K01997 - - 3.881e-198 635.0
HFD3_k127_3727864_1 amidohydrolase family K15358 - 3.5.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 439.0
HFD3_k127_3727864_2 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 426.0
HFD3_k127_3727864_3 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 371.0
HFD3_k127_3727864_4 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 285.0
HFD3_k127_3727864_5 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004284 300.0
HFD3_k127_3727864_6 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002797 257.0
HFD3_k127_3727864_7 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.00000002158 58.0
HFD3_k127_3760614_0 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases - - - 8.741e-236 746.0
HFD3_k127_3760614_1 N-terminal half of MaoC dehydratase - - - 9.738e-202 633.0
HFD3_k127_3760614_10 Rubredoxin-like zinc ribbon domain (DUF35_N) - - - 0.0000000000000000000000000000000000000000000000000000000000000000007953 235.0
HFD3_k127_3760614_11 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000233 216.0
HFD3_k127_3760614_12 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000004553 186.0
HFD3_k127_3760614_13 P-aminobenzoate N-oxygenase AurF - - - 0.00000000000000000000000000000000000000000000692 177.0
HFD3_k127_3760614_14 IMP dehydrogenase activity - - - 0.000000000000000000000004398 111.0
HFD3_k127_3760614_2 Carboxyl transferase domain - - - 3.961e-197 620.0
HFD3_k127_3760614_3 MgtE intracellular N domain K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 562.0
HFD3_k127_3760614_4 acetyl-coa acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008883 555.0
HFD3_k127_3760614_5 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003682 547.0
HFD3_k127_3760614_6 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 477.0
HFD3_k127_3760614_7 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007037 387.0
HFD3_k127_3760614_8 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 314.0
HFD3_k127_3760614_9 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007274 254.0
HFD3_k127_3788458_0 6-phosphofructokinase activity K00850,K00895,K21071 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 569.0
HFD3_k127_3788458_1 Membrane protein, TerC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001715 274.0
HFD3_k127_3788458_2 DEAD/H associated K03724 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001148 268.0
HFD3_k127_3788458_3 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003153 267.0
HFD3_k127_3788458_4 COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000193 267.0
HFD3_k127_3788458_5 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000001152 215.0
HFD3_k127_3788458_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000002488 205.0
HFD3_k127_3799835_0 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 - 1.13.11.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 425.0
HFD3_k127_3799835_1 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000833 400.0
HFD3_k127_3799835_2 Belongs to the TtcA family K21947 - 2.8.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008715 361.0
HFD3_k127_3799835_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 327.0
HFD3_k127_3799835_4 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000002318 241.0
HFD3_k127_3799835_5 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000000009066 236.0
HFD3_k127_3799835_6 ECF sigma factor K03088 - - 0.000000000000000000000000000000000007802 143.0
HFD3_k127_3799835_7 Anti-sigma-K factor rskA - - - 0.0000000000000001776 89.0
HFD3_k127_3799835_8 ThiS family K03154 - - 0.00000000002085 69.0
HFD3_k127_3828436_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 9.322e-194 623.0
HFD3_k127_3828436_1 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 363.0
HFD3_k127_3828436_2 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000000000000000001876 162.0
HFD3_k127_3828436_3 Domain of Unknown Function (DUF748) - - - 0.0000000003925 70.0
HFD3_k127_3828436_4 bacterial OsmY and nodulation domain K04065 - - 0.0001531 49.0
HFD3_k127_3893726_0 May be the GTPase, regulating ATP sulfurylase activity K00955 GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0044237 2.7.1.25,2.7.7.4 4.105e-213 694.0
HFD3_k127_3893726_1 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 484.0
HFD3_k127_3893726_10 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000405 169.0
HFD3_k127_3893726_11 PFAM PQQ enzyme repeat - - - 0.00000000000000000002444 99.0
HFD3_k127_3893726_2 Phosphoadenosine phosphosulfate reductase family K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 424.0
HFD3_k127_3893726_3 Bacterial extracellular solute-binding protein K02048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003662 397.0
HFD3_k127_3893726_4 TIGRFAM sulfate ABC transporter K02047 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 358.0
HFD3_k127_3893726_5 COG3119 Arylsulfatase A and related enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003837 368.0
HFD3_k127_3893726_6 TIGRFAM sulfate ABC transporter K02046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004834 314.0
HFD3_k127_3893726_7 Phosphoadenosine phosphosulfate reductase K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005357 300.0
HFD3_k127_3893726_8 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000153 226.0
HFD3_k127_3893726_9 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000009635 203.0
HFD3_k127_3904554_0 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 336.0
HFD3_k127_3904554_1 molybdopterin-guanine dinucleotide biosynthesis protein K03753,K13818 - 2.7.7.77 0.000000000000000001199 96.0
HFD3_k127_3904554_2 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000001918 85.0
HFD3_k127_3922940_0 Glycosyltransferase WbsX - - - 0.0 1232.0
HFD3_k127_3922940_1 cephalosporin hydroxylase K01190,K12308 - 3.2.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 301.0
HFD3_k127_3922940_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 295.0
HFD3_k127_3922940_3 ABC transporter K01990,K09691,K09693 - 3.6.3.40 0.000000000000000000000000000000000000000000000000000000000000000005589 235.0
HFD3_k127_3922940_4 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000002519 226.0
HFD3_k127_3922940_5 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000881 229.0
HFD3_k127_3922940_6 Glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000000000000003009 185.0
HFD3_k127_3922940_7 ABC-2 type transporter K09690 - - 0.0000000000000000000000000000002125 136.0
HFD3_k127_3922940_8 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate K07749 - 2.8.3.16 0.0000000000002119 72.0
HFD3_k127_3929272_0 introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX K03404,K03405 - 6.6.1.1 6.239e-208 656.0
HFD3_k127_3929272_1 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 565.0
HFD3_k127_3929272_2 Aconitase family (aconitate hydratase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 509.0
HFD3_k127_3929272_3 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K01003,K01841 - 4.1.1.3,5.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 418.0
HFD3_k127_3929272_4 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000003311 227.0
HFD3_k127_3929272_5 Protein of unknown function (DUF1566) - - - 0.00000000000000000000000000000000000000000002175 187.0
HFD3_k127_3929272_6 membrane - - - 0.0000000000005951 81.0
HFD3_k127_3932199_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 588.0
HFD3_k127_3932199_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006818 551.0
HFD3_k127_3932199_10 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases K01090 - 3.1.3.16 0.00000000000000000000000000000000000000000155 175.0
HFD3_k127_3932199_11 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000001608 157.0
HFD3_k127_3932199_12 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000005032 138.0
HFD3_k127_3932199_13 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000001106 109.0
HFD3_k127_3932199_14 SMART helix-turn-helix domain protein - - - 0.00000000000009936 78.0
HFD3_k127_3932199_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004832 412.0
HFD3_k127_3932199_3 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000995 353.0
HFD3_k127_3932199_4 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 361.0
HFD3_k127_3932199_5 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 351.0
HFD3_k127_3932199_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 319.0
HFD3_k127_3932199_7 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001079 249.0
HFD3_k127_3932199_8 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000002687 237.0
HFD3_k127_3932199_9 TIGRFAM riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000001106 174.0
HFD3_k127_3932505_0 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 350.0
HFD3_k127_3932505_1 Protein of unknown function (DUF1499) - - - 0.0000000000000000000000000000000000000001505 154.0
HFD3_k127_3932505_2 Adenylate cyclase - - - 0.0000000000003871 77.0
HFD3_k127_3935342_0 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 362.0
HFD3_k127_3935342_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000001314 222.0
HFD3_k127_3936279_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009534 582.0
HFD3_k127_3936279_1 Binding-protein-dependent transport systems inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 328.0
HFD3_k127_3936279_10 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.000000000005197 76.0
HFD3_k127_3936279_11 Methyltransferase domain - - - 0.00000000005086 74.0
HFD3_k127_3936279_12 CO dehydrogenase flavoprotein domain protein K03519 - 1.2.5.3 0.0000302 55.0
HFD3_k127_3936279_2 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 313.0
HFD3_k127_3936279_3 Trypsin-like serine protease K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004101 300.0
HFD3_k127_3936279_4 PFAM Binding-protein-dependent transport system inner membrane component K02025,K15771 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 295.0
HFD3_k127_3936279_5 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 301.0
HFD3_k127_3936279_6 PFAM Binding-protein-dependent transport system inner membrane component K02025,K15771 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001857 279.0
HFD3_k127_3936279_7 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002308 269.0
HFD3_k127_3936279_8 coenzyme F390 K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000001225 192.0
HFD3_k127_3936279_9 CO dehydrogenase flavoprotein C-terminal domain K03519,K16878 - 1.2.5.3,1.3.99.8 0.0000000000000000000000000000000000000000000006816 176.0
HFD3_k127_3936302_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 472.0
HFD3_k127_3966055_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000042 355.0
HFD3_k127_3966055_1 reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000006378 183.0
HFD3_k127_3966055_10 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006643,GO:0006644,GO:0006664,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009245,GO:0009247,GO:0009259,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0019637,GO:0019693,GO:0019752,GO:0019842,GO:0030312,GO:0031177,GO:0032787,GO:0033218,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046483,GO:0046493,GO:0048037,GO:0051186,GO:0051192,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072341,GO:0072521,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901360,GO:1901564,GO:1901576,GO:1903509 - 0.00002618 56.0
HFD3_k127_3966055_11 PFAM GCN5-related N-acetyltransferase - - - 0.0000478 49.0
HFD3_k127_3966055_12 amino acid adenylation domain protein - - - 0.00008123 52.0
HFD3_k127_3966055_13 MacB-like periplasmic core domain K02004 - - 0.0003635 53.0
HFD3_k127_3966055_2 ABC transporter K02003 - - 0.000000000000000000000000000000000000004184 163.0
HFD3_k127_3966055_4 - - - - 0.000000000000000000000000000007761 123.0
HFD3_k127_3966055_5 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0008693,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019171,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0047451,GO:0071704,GO:0072330,GO:1901576 4.2.1.59 0.000000000000000000000001119 109.0
HFD3_k127_3966055_6 Nitroreductase family K04719 - 1.13.11.79 0.000000000000000003173 96.0
HFD3_k127_3966055_7 Glycine zipper - - - 0.0000000000000926 79.0
HFD3_k127_3966055_8 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000001837 65.0
HFD3_k127_3966055_9 Beta-lactamase superfamily domain - - - 0.000000004214 63.0
HFD3_k127_3966089_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0 1058.0
HFD3_k127_3980990_0 Orn/Lys/Arg decarboxylase, C-terminal domain K01584 - 4.1.1.19 0.0 1324.0
HFD3_k127_3980990_1 Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 0.0 1292.0
HFD3_k127_3980990_10 PFAM extracellular solute-binding protein family 3 K02030,K09969,K10001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005535 278.0
HFD3_k127_3980990_11 outer membrane porin, OprD family - - - 0.000000000000000000000000000000000000000000000000000000000000000006768 253.0
HFD3_k127_3980990_12 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000007244 201.0
HFD3_k127_3980990_13 response regulator - - - 0.000000000000000000000000000000000000000000000000000001835 201.0
HFD3_k127_3980990_14 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000003818 165.0
HFD3_k127_3980990_15 - - - - 0.00000000000000000000000000000000000000009933 166.0
HFD3_k127_3980990_16 - - - - 0.000000000000000000000000000000002787 147.0
HFD3_k127_3980990_17 phosphorelay signal transduction system K14987 - - 0.00000000000000000000000000008178 119.0
HFD3_k127_3980990_18 Ion channel - - - 0.00000000000000000000000003906 125.0
HFD3_k127_3980990_19 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K01810,K13810 - 2.2.1.2,5.3.1.9 0.000000008453 68.0
HFD3_k127_3980990_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 481.0
HFD3_k127_3980990_20 Predicted Permease Membrane Region K07085 - - 0.00000008438 53.0
HFD3_k127_3980990_3 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 494.0
HFD3_k127_3980990_4 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009219 416.0
HFD3_k127_3980990_5 Domain of unknown function (DUF4105) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 398.0
HFD3_k127_3980990_6 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 343.0
HFD3_k127_3980990_7 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 337.0
HFD3_k127_3980990_8 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006377 321.0
HFD3_k127_3980990_9 Biotin-lipoyl like K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002775 293.0
HFD3_k127_3983456_0 PQQ-like domain K00117 - 1.1.5.2 9.57e-290 908.0
HFD3_k127_3983456_1 Bacterial periplasmic substrate-binding proteins K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000005334 245.0
HFD3_k127_3983456_2 DNA ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000002177 222.0
HFD3_k127_3983456_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000005364 104.0
HFD3_k127_3983507_0 (ABC) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006361 455.0
HFD3_k127_3983507_1 Putative glycosyl hydrolase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008925 347.0
HFD3_k127_3983507_2 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000000000002167 85.0
HFD3_k127_3983507_3 ACT domain - - - 0.0000000592 63.0
HFD3_k127_3983507_4 Universal stress protein - - - 0.000001976 58.0
HFD3_k127_3983507_5 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00007082 53.0
HFD3_k127_3994636_0 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 333.0
HFD3_k127_3994636_1 Protein of unknown function (DUF1706) - - - 0.0000000001816 68.0
HFD3_k127_4014610_0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214,K02438 - 3.2.1.196,3.2.1.68 4.4e-323 1038.0
HFD3_k127_4014610_1 synthase K00705,K06044 GO:0000272,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0030978,GO:0030980,GO:0034637,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0047470,GO:0071704,GO:1901575,GO:1901576 2.4.1.25,5.4.99.15 1.696e-295 937.0
HFD3_k127_4014610_10 transmembrane transport - - - 0.0000000000000000000000000000000000000000000000000000000012 208.0
HFD3_k127_4014610_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000002629 174.0
HFD3_k127_4014610_12 ChrR Cupin-like domain - - - 0.00000000000000000000000000000000000000004376 159.0
HFD3_k127_4014610_13 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000001284 168.0
HFD3_k127_4014610_14 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000002977 167.0
HFD3_k127_4014610_15 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000007348 144.0
HFD3_k127_4014610_16 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.000000000000000000002359 102.0
HFD3_k127_4014610_17 Glycosyl transferases group 1 K13057 - 2.4.1.245 0.000000005531 68.0
HFD3_k127_4014610_2 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.029e-231 775.0
HFD3_k127_4014610_3 Alpha amylase, catalytic domain K01236 - 3.2.1.141 3.936e-210 702.0
HFD3_k127_4014610_4 glycogen (starch) synthase activity K16148 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901576 2.4.1.342 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 404.0
HFD3_k127_4014610_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 350.0
HFD3_k127_4014610_6 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 320.0
HFD3_k127_4014610_7 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 297.0
HFD3_k127_4014610_8 branched-chain amino acid ABC transporter ATP-binding protein K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002518 276.0
HFD3_k127_4014610_9 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000002969 238.0
HFD3_k127_4046841_0 Bacterial DNA polymerase III alpha subunit - - - 7.318e-307 975.0
HFD3_k127_4046841_1 dehydrogenase - - - 6.792e-209 669.0
HFD3_k127_4046841_10 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K14161 - - 0.000000000000000000000000000000000000000000000000000000001308 224.0
HFD3_k127_4046841_11 transferase activity, transferring glycosyl groups K20444 - - 0.000000000000000000000000000000000000000000000000000000184 221.0
HFD3_k127_4046841_12 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000002111 199.0
HFD3_k127_4046841_13 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000009831 202.0
HFD3_k127_4046841_14 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000001766 171.0
HFD3_k127_4046841_15 Putative regulatory protein - - - 0.000000000000000000000000000000007798 136.0
HFD3_k127_4046841_16 Amidohydrolase K07045 - - 0.00000000000000000000000001483 120.0
HFD3_k127_4046841_17 recA bacterial DNA recombination protein - - - 0.000000000000000000000005245 109.0
HFD3_k127_4046841_18 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily K03430 - 2.6.1.37 0.00000004907 63.0
HFD3_k127_4046841_2 COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008569 594.0
HFD3_k127_4046841_3 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 539.0
HFD3_k127_4046841_4 PFAM glycosyl transferase group 1 K15521 - 2.4.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007147 370.0
HFD3_k127_4046841_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 302.0
HFD3_k127_4046841_6 membrane - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009016 294.0
HFD3_k127_4046841_7 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001509 284.0
HFD3_k127_4046841_8 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005385 257.0
HFD3_k127_4046841_9 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004582 252.0
HFD3_k127_4055052_0 Biotin carboxylase C-terminal domain - - - 0.0 1331.0
HFD3_k127_4055052_1 GTP-binding protein TypA K06207 - - 5.447e-260 815.0
HFD3_k127_4055052_10 Amidohydrolase family K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 441.0
HFD3_k127_4055052_11 Adenylosuccinate lyase C-terminus K01756,K01857 - 4.3.2.2,5.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 422.0
HFD3_k127_4055052_12 Peptidase, M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 431.0
HFD3_k127_4055052_13 cell redox homeostasis K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 404.0
HFD3_k127_4055052_14 PBP superfamily domain K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 353.0
HFD3_k127_4055052_15 Histone deacetylase domain K04768 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 361.0
HFD3_k127_4055052_16 Binding-protein-dependent transport system inner membrane component K05773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007065 304.0
HFD3_k127_4055052_17 serine-type endopeptidase activity K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 303.0
HFD3_k127_4055052_18 Belongs to the ABC transporter superfamily K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009721 320.0
HFD3_k127_4055052_19 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02045,K02049,K02068,K02071,K06857,K10112,K11072 - 3.6.3.25,3.6.3.30,3.6.3.31,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009489 317.0
HFD3_k127_4055052_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 1.72e-206 672.0
HFD3_k127_4055052_20 Alpha beta hydrolase K14731 - 3.1.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 301.0
HFD3_k127_4055052_21 PFAM Phosphomethylpyrimidine kinase type-1 K00941,K14153 - 2.5.1.3,2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008028 288.0
HFD3_k127_4055052_22 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002994 287.0
HFD3_k127_4055052_23 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005702 289.0
HFD3_k127_4055052_24 Alanine-glyoxylate amino-transferase K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006947 270.0
HFD3_k127_4055052_25 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002594 253.0
HFD3_k127_4055052_26 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000072 254.0
HFD3_k127_4055052_27 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009337 248.0
HFD3_k127_4055052_28 molybdate ABC transporter, permease protein K02017,K02018 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000004932 238.0
HFD3_k127_4055052_29 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.00000000000000000000000000000000000000000000000000000000000000004174 235.0
HFD3_k127_4055052_3 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 5.914e-205 657.0
HFD3_k127_4055052_30 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000006431 239.0
HFD3_k127_4055052_31 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000002866 213.0
HFD3_k127_4055052_32 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000008576 210.0
HFD3_k127_4055052_33 Inositol monophosphatase - - - 0.0000000000000000000000000000000000000000000000000000002532 202.0
HFD3_k127_4055052_34 decarboxylase K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000000003437 208.0
HFD3_k127_4055052_35 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000002684 192.0
HFD3_k127_4055052_36 Enoyl-(Acyl carrier protein) reductase K00034 - 1.1.1.47 0.00000000000000000000000000000000000000000000000000007709 198.0
HFD3_k127_4055052_37 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000001731 182.0
HFD3_k127_4055052_38 NADPH-dependent FMN reductase K00299 - 1.5.1.38 0.000000000000000000000000000000000000000000000002883 188.0
HFD3_k127_4055052_39 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768,K09565 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.000000000000000000000000000000000000000000002187 190.0
HFD3_k127_4055052_4 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008826 578.0
HFD3_k127_4055052_40 Family of unknown function (DUF1028) - - - 0.00000000000000000000000000000000000000000003434 169.0
HFD3_k127_4055052_41 Protein of unknown function (DUF1566) - - - 0.000000000000000000000000000000000000002249 164.0
HFD3_k127_4055052_42 - - - - 0.0000000000000000000000000000000001706 140.0
HFD3_k127_4055052_43 pyridoxamine 5-phosphate - - - 0.0000000000000000000000000000000007026 136.0
HFD3_k127_4055052_44 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000001472 140.0
HFD3_k127_4055052_45 Methyltransferase domain - - - 0.0000000000000000000000000000002189 143.0
HFD3_k127_4055052_47 membrane transporter protein K07090 - - 0.000000000000000002755 94.0
HFD3_k127_4055052_48 response regulator - - - 0.0000000000000007758 83.0
HFD3_k127_4055052_49 PFAM regulatory protein LysR K02019 - - 0.00000000000005382 78.0
HFD3_k127_4055052_5 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 560.0
HFD3_k127_4055052_50 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.000000003148 62.0
HFD3_k127_4055052_51 - - - - 0.00000001776 65.0
HFD3_k127_4055052_52 - K09794 - - 0.00008779 49.0
HFD3_k127_4055052_6 III protein, CoA-transferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 526.0
HFD3_k127_4055052_7 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005776 526.0
HFD3_k127_4055052_8 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 517.0
HFD3_k127_4055052_9 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K04091 - 1.14.14.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 474.0
HFD3_k127_4059975_0 Adenylate and Guanylate cyclase catalytic domain - - - 5.017e-285 912.0
HFD3_k127_4059975_1 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 1.101e-262 835.0
HFD3_k127_4059975_10 NADPH-dependent FMN reductase K19784 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004169 265.0
HFD3_k127_4059975_11 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002295 245.0
HFD3_k127_4059975_12 CO dehydrogenase flavoprotein C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000003989 210.0
HFD3_k127_4059975_13 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS K19819 - 1.5.99.4 0.0000000000000000000000000000000000000000000000000002693 195.0
HFD3_k127_4059975_14 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518,K13483 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000874 185.0
HFD3_k127_4059975_15 oxidoreductase activity, acting on CH-OH group of donors K09386 - - 0.0000000000000000000000000001376 120.0
HFD3_k127_4059975_16 Methyltransferase domain K07003 - - 0.000000000000000000003802 104.0
HFD3_k127_4059975_17 Regulator of chromosome condensation (RCC1) repeat - - - 0.00000000000001089 87.0
HFD3_k127_4059975_18 - - - - 0.0000000347 58.0
HFD3_k127_4059975_2 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 567.0
HFD3_k127_4059975_3 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005449 552.0
HFD3_k127_4059975_4 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 401.0
HFD3_k127_4059975_5 ABC transporter permease K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 299.0
HFD3_k127_4059975_6 membrane K07148 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004434 322.0
HFD3_k127_4059975_7 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001563 283.0
HFD3_k127_4059975_8 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002624 276.0
HFD3_k127_4059975_9 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006743 286.0
HFD3_k127_4075240_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004455,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 526.0
HFD3_k127_4075240_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000001091 231.0
HFD3_k127_4075240_2 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000003583 206.0
HFD3_k127_4075240_3 ACT domain K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.00000000000000000000000000000006662 128.0
HFD3_k127_4083811_0 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006303 316.0
HFD3_k127_4083811_1 protein conserved in bacteria K09766 - - 0.0000000009533 63.0
HFD3_k127_4101436_0 AAA ATPase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 533.0
HFD3_k127_4101436_1 AAA ATPase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005993 531.0
HFD3_k127_4101436_2 alpha-L-arabinofuranosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004094 502.0
HFD3_k127_4101436_3 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000001943 230.0
HFD3_k127_4101436_4 Transcriptional regulatory protein, C terminal - - - 0.00000000000004573 87.0
HFD3_k127_4101436_5 Alpha beta hydrolase - - - 0.0000000000001598 85.0
HFD3_k127_4101436_6 Amidohydrolase K07045 - - 0.0001516 48.0
HFD3_k127_4105582_0 Belongs to the enoyl-CoA hydratase isomerase family K07516 - 1.1.1.35 1.5e-278 886.0
HFD3_k127_4105582_1 Luciferase-like monooxygenase - - - 1.224e-202 638.0
HFD3_k127_4105582_10 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000006025 173.0
HFD3_k127_4105582_11 methyltransferase - - - 0.0000000000000000000000000000353 128.0
HFD3_k127_4105582_12 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.0000000000000000000000000001123 125.0
HFD3_k127_4105582_13 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - - 0.0000000000000000000001159 107.0
HFD3_k127_4105582_14 - - - - 0.000000000000006439 76.0
HFD3_k127_4105582_15 Bacterial extracellular solute-binding protein - - - 0.0000000000002584 73.0
HFD3_k127_4105582_16 - - - - 0.0000000001202 65.0
HFD3_k127_4105582_2 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 298.0
HFD3_k127_4105582_3 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007953 290.0
HFD3_k127_4105582_4 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002627 271.0
HFD3_k127_4105582_5 Tryptophan halogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003729 266.0
HFD3_k127_4105582_6 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007351 261.0
HFD3_k127_4105582_7 COG0451 Nucleoside-diphosphate-sugar epimerases - - - 0.000000000000000000000000000000000000000000000001185 186.0
HFD3_k127_4105582_8 PFAM luciferase-like - - - 0.00000000000000000000000000000000000000000000001809 194.0
HFD3_k127_4105582_9 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000000000000000000005079 174.0
HFD3_k127_4126863_0 COG0488 ATPase components of ABC transporters with duplicated ATPase domains - - - 2.227e-264 824.0
HFD3_k127_4126863_1 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000908 542.0
HFD3_k127_4126863_10 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009314 298.0
HFD3_k127_4126863_11 3'-5' exonuclease K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000005277 268.0
HFD3_k127_4126863_12 Transcriptional regulator sugar kinase K00886 - 2.7.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000001076 258.0
HFD3_k127_4126863_13 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000005734 179.0
HFD3_k127_4126863_14 Exopolyphosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000005523 145.0
HFD3_k127_4126863_15 - - - - 0.0000000000000000000000115 113.0
HFD3_k127_4126863_17 Phosphohistidine phosphatase, SixA K08296 - - 0.000000000000000001499 92.0
HFD3_k127_4126863_18 Belongs to the beta-ketoacyl-ACP synthases family K14660 - - 0.0000000846 56.0
HFD3_k127_4126863_2 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 404.0
HFD3_k127_4126863_3 Belongs to the FGGY kinase family K00851 - 2.7.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 392.0
HFD3_k127_4126863_4 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 386.0
HFD3_k127_4126863_5 amino acid K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 342.0
HFD3_k127_4126863_6 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 340.0
HFD3_k127_4126863_7 KR domain K00065 - 1.1.1.127 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006428 355.0
HFD3_k127_4126863_8 mannose-ethanolamine phosphotransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 331.0
HFD3_k127_4126863_9 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 316.0
HFD3_k127_4146245_0 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000008709 229.0
HFD3_k127_4146245_1 AhpC/TSA family - - - 0.000000000000000000000000000000000000000000000000000000000001328 215.0
HFD3_k127_4146245_2 Nitronate monooxygenase K00459,K02371 - 1.13.12.16,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000003601 220.0
HFD3_k127_4146245_3 - - - - 0.00000000000000000000000000000000000000000000000000000009883 203.0
HFD3_k127_4182637_0 Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 1.703e-256 808.0
HFD3_k127_4182637_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00001203 49.0
HFD3_k127_4188940_0 Bacterial transcriptional activator domain K12132 - 2.7.11.1 2.603e-266 850.0
HFD3_k127_4202106_0 SNF2 family N-terminal domain - - - 3.73e-310 980.0
HFD3_k127_4202106_1 SNARE associated Golgi protein - - - 0.00000000000000000000000000001835 126.0
HFD3_k127_4204296_0 Thiol disulfide interchange protein K04084,K08344 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 622.0
HFD3_k127_4204296_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 412.0
HFD3_k127_4204296_2 cytochrome P450 K00493,K21257 - 1.14.14.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 393.0
HFD3_k127_4204296_3 Protein of unknown function (DUF3500) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005736 310.0
HFD3_k127_4204296_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001057 248.0
HFD3_k127_4204296_5 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.0000000000000000000000000000000000000000000000000009121 189.0
HFD3_k127_4218419_0 - - - - 0.000000000000000000000000000000000000000000000000000001202 219.0
HFD3_k127_4218419_1 PFAM Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000001319 203.0
HFD3_k127_4218419_2 Glycosyl transferases group 1 K08256 - 2.4.1.345 0.000000000000002207 91.0
HFD3_k127_4219150_0 PFAM AMP-dependent synthetase and ligase - - - 4.259e-224 707.0
HFD3_k127_4219150_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 3.701e-205 648.0
HFD3_k127_4219150_10 MmgE PrpD family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 327.0
HFD3_k127_4219150_11 Protein of unknown function (DUF3750) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003478 279.0
HFD3_k127_4219150_12 ABC-type Fe3 transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004199 279.0
HFD3_k127_4219150_13 spore germination - - - 0.000000000000000000000000000000000000000000000000000000000000000008922 238.0
HFD3_k127_4219150_14 P-aminobenzoate N-oxygenase AurF - - - 0.0000000000000000000000000000000000000000000000000000000000000005192 231.0
HFD3_k127_4219150_15 ribonucleoside-diphosphate reductase activity K07735 - - 0.000000000000000000000000000000000000000000000000000005808 196.0
HFD3_k127_4219150_16 PFAM Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000005085 145.0
HFD3_k127_4219150_17 - - - - 0.000000000000000000000003385 104.0
HFD3_k127_4219150_18 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.0000000000000000000014 102.0
HFD3_k127_4219150_19 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.000000000000000001716 96.0
HFD3_k127_4219150_2 peptidase, M20 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 609.0
HFD3_k127_4219150_20 Metallo-beta-lactamase superfamily - - - 0.000001602 51.0
HFD3_k127_4219150_21 Uncharacterized protein conserved in bacteria (DUF2059) K09924 - - 0.0003401 51.0
HFD3_k127_4219150_3 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 552.0
HFD3_k127_4219150_4 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009403 537.0
HFD3_k127_4219150_5 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 458.0
HFD3_k127_4219150_6 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009908 354.0
HFD3_k127_4219150_7 TOBE domain K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 350.0
HFD3_k127_4219150_8 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008173 326.0
HFD3_k127_4219150_9 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 329.0
HFD3_k127_4223229_0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 6.543e-286 897.0
HFD3_k127_4223229_1 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 427.0
HFD3_k127_4223229_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 399.0
HFD3_k127_4223229_3 PFAM Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 305.0
HFD3_k127_4223229_4 - - - - 0.00000000000000000002763 95.0
HFD3_k127_4223229_5 CBS domain - GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0030312,GO:0035821,GO:0036293,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052564,GO:0052572,GO:0070482,GO:0071944,GO:0075136 - 0.0001224 52.0
HFD3_k127_4247556_0 copper-translocating P-type ATPase K17686 - 3.6.3.54 5.462e-317 989.0
HFD3_k127_4247556_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 4.63e-289 913.0
HFD3_k127_4247556_10 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0010487,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0043919,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 353.0
HFD3_k127_4247556_11 SMART PUA domain containing protein K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 324.0
HFD3_k127_4247556_12 Glycosyltransferase family 28 N-terminal domain K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 313.0
HFD3_k127_4247556_13 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000003173 224.0
HFD3_k127_4247556_14 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000000000000000238 207.0
HFD3_k127_4247556_15 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000001781 189.0
HFD3_k127_4247556_16 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000000000000000000001141 198.0
HFD3_k127_4247556_17 Peptidase C13 family - - - 0.00000000000000000000000000000000000000000000001035 194.0
HFD3_k127_4247556_18 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000002976 168.0
HFD3_k127_4247556_19 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.00000000000000000000000000000000000000003581 163.0
HFD3_k127_4247556_2 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335,K03469 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7,3.1.26.4 7.75e-200 647.0
HFD3_k127_4247556_20 Belongs to the PdaD family K02626 - 4.1.1.19 0.00000000000000000000000000000000000001421 154.0
HFD3_k127_4247556_21 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.0000000000000000000000000000000002753 139.0
HFD3_k127_4247556_22 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000000000005515 134.0
HFD3_k127_4247556_23 Tellurite resistance protein TehB - - - 0.000000000000000000000000000007728 126.0
HFD3_k127_4247556_24 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000000000000000002384 124.0
HFD3_k127_4247556_25 Methyltransferase domain - - - 0.0000000000000000000000005085 121.0
HFD3_k127_4247556_26 Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.000000000000000000000002177 108.0
HFD3_k127_4247556_27 Cytochrome c K17222 - - 0.0000000000000000000009173 109.0
HFD3_k127_4247556_28 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.00000000000000000004328 102.0
HFD3_k127_4247556_29 PFAM Copper resistance protein CopC K07156 - - 0.0000000000000000004482 98.0
HFD3_k127_4247556_3 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 580.0
HFD3_k127_4247556_30 response to copper ion K07156 - - 0.0000000000002251 78.0
HFD3_k127_4247556_31 Modulates RecA activity K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000003834 74.0
HFD3_k127_4247556_32 - - - - 0.000006415 58.0
HFD3_k127_4247556_33 nitroreductase - - - 0.0003012 51.0
HFD3_k127_4247556_4 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007042 547.0
HFD3_k127_4247556_5 PFAM MgsA AAA ATPase C terminal K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007687 499.0
HFD3_k127_4247556_6 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 490.0
HFD3_k127_4247556_7 PFAM type II secretion system protein E K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005261 431.0
HFD3_k127_4247556_8 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 386.0
HFD3_k127_4247556_9 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 384.0
HFD3_k127_4252938_0 Arginosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005265 605.0
HFD3_k127_4252938_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 334.0
HFD3_k127_4252938_2 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000001717 220.0
HFD3_k127_4252938_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000002065 158.0
HFD3_k127_4252938_4 Belongs to the ComB family K05979 - 3.1.3.71 0.00000000000000000000000001606 120.0
HFD3_k127_4252938_5 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000001971 120.0
HFD3_k127_4261334_0 Hydantoinase/oxoprolinase - - - 3.523e-235 766.0
HFD3_k127_4261334_1 Hydantoinase B/oxoprolinase - - - 7.181e-224 710.0
HFD3_k127_4261334_10 - - - - 0.00000000000001017 76.0
HFD3_k127_4261334_12 - - - - 0.0000002646 63.0
HFD3_k127_4261334_2 PFAM glycosyl transferase family 35 K00688 - 2.4.1.1 8.956e-194 623.0
HFD3_k127_4261334_3 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 453.0
HFD3_k127_4261334_4 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004619 409.0
HFD3_k127_4261334_5 Alpha/beta hydrolase family K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002045 285.0
HFD3_k127_4261334_6 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003699 280.0
HFD3_k127_4261334_7 Extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000006674 217.0
HFD3_k127_4261334_8 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000002774 208.0
HFD3_k127_4261334_9 PFAM Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000008624 181.0
HFD3_k127_4297802_0 Alpha amylase, catalytic domain K05343 - 3.2.1.1,5.4.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008628 303.0
HFD3_k127_4297802_1 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000001679 203.0
HFD3_k127_4308901_0 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs - - - 9.111e-246 783.0
HFD3_k127_4308901_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004353 373.0
HFD3_k127_4308901_10 Cupin domain - - - 0.00000000000000000000000000007636 121.0
HFD3_k127_4308901_11 dTDP biosynthetic process K00560,K00943 - 2.1.1.45,2.7.4.9 0.0001356 48.0
HFD3_k127_4308901_2 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 346.0
HFD3_k127_4308901_3 PFAM Branched-chain amino acid transport system permease component K01997,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005932 276.0
HFD3_k127_4308901_4 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000001059 251.0
HFD3_k127_4308901_5 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000001274 240.0
HFD3_k127_4308901_6 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS - - - 0.0000000000000000000000000000000000000000000000000000006428 200.0
HFD3_k127_4308901_7 Belongs to the HpcH HpaI aldolase family K01630,K02510 - 4.1.2.20,4.1.2.52 0.0000000000000000000000000000000000000000005835 167.0
HFD3_k127_4308901_8 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000003882 154.0
HFD3_k127_4308901_9 cheY-homologous receiver domain - - - 0.000000000000000000000000000003703 124.0
HFD3_k127_431614_0 Xaa-Pro aminopeptidase K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 444.0
HFD3_k127_431614_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008339 385.0
HFD3_k127_431614_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000007344 170.0
HFD3_k127_431614_3 Tyrosine phosphatase family - - - 0.00000000000000000000000000008332 121.0
HFD3_k127_4324589_0 Sigma-54 interaction domain K15836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000428 581.0
HFD3_k127_4324589_1 Pyridine nucleotide-disulphide oxidoreductase K03885,K10716 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 533.0
HFD3_k127_4324589_10 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000002447 222.0
HFD3_k127_4324589_11 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000297 177.0
HFD3_k127_4324589_12 DoxX K15977 - - 0.00000000000000000000000000000000000001139 150.0
HFD3_k127_4324589_13 PFAM sigma-70 region 2 domain protein K03088 - - 0.000000000000000000000000000000000005935 148.0
HFD3_k127_4324589_14 Putative DNA-binding domain - - - 0.00000000000000000000000000000000004743 153.0
HFD3_k127_4324589_15 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000006403 132.0
HFD3_k127_4324589_16 Predicted integral membrane protein (DUF2282) - - - 0.000000000000000000000000009943 111.0
HFD3_k127_4324589_17 Membrane - - - 0.0000000000000000000000007341 114.0
HFD3_k127_4324589_18 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.000000000000005973 79.0
HFD3_k127_4324589_19 - - - - 0.000000000006101 72.0
HFD3_k127_4324589_2 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 497.0
HFD3_k127_4324589_20 OsmC-like protein - - - 0.000002943 53.0
HFD3_k127_4324589_21 Putative zinc-finger - - - 0.000005661 52.0
HFD3_k127_4324589_3 belongs to the UPF0276 family K09930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 334.0
HFD3_k127_4324589_4 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002328 290.0
HFD3_k127_4324589_5 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002902 280.0
HFD3_k127_4324589_6 phosphorelay sensor kinase activity K01768,K07315 - 3.1.3.3,4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000119 278.0
HFD3_k127_4324589_7 Histidine phosphatase superfamily (branch 1) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003057 244.0
HFD3_k127_4324589_8 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005187 243.0
HFD3_k127_4324589_9 Aldolase/RraA K10218 - 4.1.3.17 0.00000000000000000000000000000000000000000000000000000000000006764 223.0
HFD3_k127_4325171_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000087 305.0
HFD3_k127_4325171_1 Type IV pilus assembly protein PilM; K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000131 251.0
HFD3_k127_4325171_2 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000001066 226.0
HFD3_k127_4325171_3 COG3167 Tfp pilus assembly protein PilO K02664 - - 0.00000000000000684 83.0
HFD3_k127_4325171_4 Fimbrial assembly protein (PilN) K02663 - - 0.00000000000219 77.0
HFD3_k127_4325171_5 AMIN domain K02666 - - 0.000000001023 69.0
HFD3_k127_4325171_6 type IV pilus modification protein PilV K02671,K02681,K10927 - - 0.000003338 58.0
HFD3_k127_4325171_7 Pilus assembly protein, PilP K02665 - - 0.0001529 53.0
HFD3_k127_4330167_0 ABC transporter transmembrane region K06147,K18890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003835 563.0
HFD3_k127_4330167_1 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009076 459.0
HFD3_k127_4330167_10 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002342 289.0
HFD3_k127_4330167_11 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000007666 268.0
HFD3_k127_4330167_12 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000107 251.0
HFD3_k127_4330167_13 Binding-protein-dependent transport system inner membrane component K02054 - - 0.000000000000000000000000000000000000000000000000000000000000000007353 234.0
HFD3_k127_4330167_14 Domain of unknown function DUF108 - - - 0.00000000000000000000000000000000000000000000000000000000000000002964 231.0
HFD3_k127_4330167_15 Protein of unknown function (DUF2400) - - - 0.000000000000000000000000000000000000000000000000000000000000001971 228.0
HFD3_k127_4330167_16 Binding-protein-dependent transport system inner membrane component K02053 - - 0.000000000000000000000000000000000000000000000000000000000000006625 235.0
HFD3_k127_4330167_17 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000002471 213.0
HFD3_k127_4330167_18 Allophanate hydrolase subunit 1 K06351 - - 0.000000000000000000000000000000000000000000000000000000003882 211.0
HFD3_k127_4330167_19 Belongs to the UPF0282 family K07022 - - 0.0000000000000000000000000000000000000000000000000000000204 209.0
HFD3_k127_4330167_2 ABC transporter transmembrane region K06147,K18889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000421 424.0
HFD3_k127_4330167_20 Aminoacyl-tRNA editing domain - - - 0.000000000000000000000000000000000002129 156.0
HFD3_k127_4330167_21 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.0000000000000000000000000000002045 129.0
HFD3_k127_4330167_23 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.00000000000000000000000002656 112.0
HFD3_k127_4330167_24 Redoxin - - - 0.000000000000000000005437 95.0
HFD3_k127_4330167_25 methylated DNA-protein cysteine methyltransferase K07443 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 - 0.0000000000000000000139 99.0
HFD3_k127_4330167_26 Protein conserved in bacteria K09986 - - 0.0000000000000000005581 94.0
HFD3_k127_4330167_27 Redoxin - - - 0.00000002583 63.0
HFD3_k127_4330167_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 373.0
HFD3_k127_4330167_4 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 387.0
HFD3_k127_4330167_5 Bacterial extracellular solute-binding protein K02055 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 359.0
HFD3_k127_4330167_6 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005552 346.0
HFD3_k127_4330167_7 Peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003804 350.0
HFD3_k127_4330167_8 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008267 321.0
HFD3_k127_4330167_9 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 295.0
HFD3_k127_4338211_0 Aldo Keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 453.0
HFD3_k127_4338211_1 Sugar (and other) transporter K03446 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 383.0
HFD3_k127_4338211_2 phosphogluconate dehydrogenase (decarboxylating) activity K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 357.0
HFD3_k127_4338211_3 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 343.0
HFD3_k127_4338211_4 decarboxylase K01607 - 4.1.1.44 0.000000000000000000000000000001773 128.0
HFD3_k127_4338211_5 - - - - 0.000000000000004661 81.0
HFD3_k127_4338464_0 Proton-conducting membrane transporter K00342,K05575 - 1.6.5.3 4.309e-203 647.0
HFD3_k127_4338464_1 NADH-quinone oxidoreductase chain L K00341,K05577 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 554.0
HFD3_k127_4338464_10 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 300.0
HFD3_k127_4338464_11 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 291.0
HFD3_k127_4338464_12 NIPSNAP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001257 251.0
HFD3_k127_4338464_13 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000254 241.0
HFD3_k127_4338464_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000002359 224.0
HFD3_k127_4338464_15 oxidoreductase - - - 0.00000000000000000000000000000000000000003677 167.0
HFD3_k127_4338464_16 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000005149 144.0
HFD3_k127_4338464_17 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000007295 145.0
HFD3_k127_4338464_18 4Fe-4S dicluster domain K00338,K02573,K03941 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000001032 149.0
HFD3_k127_4338464_19 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 - 1.6.5.3 0.000000000000000000000000000008112 123.0
HFD3_k127_4338464_2 Epoxide hydrolase N terminus K01253 - 3.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 531.0
HFD3_k127_4338464_20 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K00332 - 1.6.5.3 0.000000000000000000000000002976 116.0
HFD3_k127_4338464_21 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000004041 105.0
HFD3_k127_4338464_22 - - - - 0.0000000000000000000007791 111.0
HFD3_k127_4338464_23 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339,K05578 - 1.6.5.3 0.00000000000000000006799 101.0
HFD3_k127_4338464_24 hydrolase activity, acting on ester bonds K01563 - 3.8.1.5 0.000000000000000004665 89.0
HFD3_k127_4338464_25 Redoxin K03564 - 1.11.1.15 0.00000000000001134 74.0
HFD3_k127_4338464_26 - - - - 0.00000000000001371 88.0
HFD3_k127_4338464_3 Cobalamin-independent synthase, Catalytic domain K00549,K22363 - 2.1.1.14,4.4.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 490.0
HFD3_k127_4338464_4 NAD binding K00333,K05579,K13378 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 446.0
HFD3_k127_4338464_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343,K05573 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 438.0
HFD3_k127_4338464_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337,K05572 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009994 362.0
HFD3_k127_4338464_7 Thiamine pyrophosphate enzyme, central domain K01576 - 4.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 362.0
HFD3_k127_4338464_8 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 319.0
HFD3_k127_4338464_9 amidohydrolase K21613 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 306.0
HFD3_k127_4344437_0 FAD dependent oxidoreductase - - - 0.0 1029.0
HFD3_k127_4344437_1 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 424.0
HFD3_k127_4344437_2 Selenoprotein B, glycine betaine sarcosine D-proline reductase family K10672 - 1.21.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008422 353.0
HFD3_k127_4344437_3 PFAM Archaeal ATPase K06921 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 302.0
HFD3_k127_4344437_4 Glycine/sarcosine/betaine reductase component B subunits - - - 0.000000000000000000000000000000000000000000000000000000000000068 229.0
HFD3_k127_4344437_5 Protein of unknown function (DUF2459) - - - 0.00000000000000000000000000000000001017 148.0
HFD3_k127_4344437_6 Selenoprotein B, glycine betaine sarcosine D-proline reductase family K10672 - 1.21.4.2 0.000000000000000000000005104 103.0
HFD3_k127_4344437_7 DSBA-like thioredoxin domain - - - 0.0000000000002923 78.0
HFD3_k127_435398_0 ABC transporter K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 525.0
HFD3_k127_435398_1 transport, permease protein K01992,K18233 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008582 462.0
HFD3_k127_435398_2 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 347.0
HFD3_k127_435398_3 Integrase - - - 0.0000000003245 65.0
HFD3_k127_4376825_0 response regulator receiver K02481,K07714,K10943 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 420.0
HFD3_k127_4376825_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 385.0
HFD3_k127_4376825_10 Belongs to the HesB IscA family K13628,K15724 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009061,GO:0009987,GO:0010467,GO:0015980,GO:0016020,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055114,GO:0071704,GO:0071840,GO:0071944,GO:1901564 - 0.0000000000000000000000000001572 118.0
HFD3_k127_4376825_11 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000007331 117.0
HFD3_k127_4376825_12 alpha beta - - - 0.00000000000000000000000008284 119.0
HFD3_k127_4376825_15 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.0000002017 53.0
HFD3_k127_4376825_2 PFAM phosphoesterase, RecJ domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 339.0
HFD3_k127_4376825_3 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.000000000000000000000000000000000000000000000000000000000000000000000000001424 260.0
HFD3_k127_4376825_4 GTP cyclohydrolase I K00950,K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009108,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0042455,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901657,GO:1901659 2.7.6.3,3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000182 257.0
HFD3_k127_4376825_5 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001057 254.0
HFD3_k127_4376825_6 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000009847 240.0
HFD3_k127_4376825_7 Molybdopterin converting factor subunit K03635,K21142 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000000819 213.0
HFD3_k127_4376825_8 Phosphonate ABC transporter K02044 - - 0.00000000000000000000000000000000000000000005532 179.0
HFD3_k127_4376825_9 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000002285 167.0
HFD3_k127_4378696_0 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms K01992,K07027,K14205 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 469.0
HFD3_k127_4378696_1 pfam nudix - - - 0.000000000000000000000000000000000000000000000000000007948 193.0
HFD3_k127_4378696_2 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000000000000000000006521 179.0
HFD3_k127_4378696_3 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.000000000000004388 85.0
HFD3_k127_4382444_0 MacB-like periplasmic core domain - - - 1.401e-241 774.0
HFD3_k127_4382444_1 Bacterial protein of unknown function (DUF899) - - - 0.000000000000000000000000000000000000000000000000000000000003561 214.0
HFD3_k127_4382444_2 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000000000000000001178 191.0
HFD3_k127_4382946_0 Amidohydrolase K07045 - - 1.224e-206 656.0
HFD3_k127_4382946_1 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 1.212e-204 663.0
HFD3_k127_4382946_10 DNA polymerase LigD polymerase domain K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 452.0
HFD3_k127_4382946_11 response regulator K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009413 429.0
HFD3_k127_4382946_12 PFAM Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 404.0
HFD3_k127_4382946_13 Sugar (and other) transporter K03446 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 374.0
HFD3_k127_4382946_14 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 350.0
HFD3_k127_4382946_15 Binding-protein-dependent transport systems inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 336.0
HFD3_k127_4382946_16 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 295.0
HFD3_k127_4382946_17 Enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000001393 257.0
HFD3_k127_4382946_18 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000002247 215.0
HFD3_k127_4382946_19 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000001324 209.0
HFD3_k127_4382946_2 PFAM amidohydrolase K07045 - - 2.789e-198 623.0
HFD3_k127_4382946_20 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000002592 207.0
HFD3_k127_4382946_21 SnoaL-like polyketide cyclase K07255 - - 0.000000000000000000000000000000000000000000000000000104 189.0
HFD3_k127_4382946_22 Ring hydroxylating beta subunit K18075 - 1.14.12.15 0.00000000000000000000000000000000000000000000000003914 190.0
HFD3_k127_4382946_23 Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000000000000001222 188.0
HFD3_k127_4382946_24 - - - - 0.000000000000000000000000000000000000000000000012 195.0
HFD3_k127_4382946_25 Histidine kinase K02668,K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000006796 186.0
HFD3_k127_4382946_26 Hemerythrin hhe cation binding - - - 0.000000000000000000000000000000000005346 145.0
HFD3_k127_4382946_27 PFAM short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000128 147.0
HFD3_k127_4382946_28 NIPSNAP - - - 0.000000000000000000000000000000003179 132.0
HFD3_k127_4382946_29 DinB superfamily - - - 0.00000000000000000000001275 110.0
HFD3_k127_4382946_3 DNA polymerase beta thumb K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 555.0
HFD3_k127_4382946_31 Two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.00000000000002197 85.0
HFD3_k127_4382946_4 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases large terminal subunit K16319,K18074 - 1.14.12.1,1.14.12.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005699 529.0
HFD3_k127_4382946_5 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 517.0
HFD3_k127_4382946_6 Protein of unknown function (DUF917) K09703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 501.0
HFD3_k127_4382946_7 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000818 502.0
HFD3_k127_4382946_8 solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008892 475.0
HFD3_k127_4382946_9 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 486.0
HFD3_k127_4388611_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 580.0
HFD3_k127_4388611_1 Phytanoyl-CoA dioxygenase (PhyH) K10674 - 1.14.11.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003852 455.0
HFD3_k127_4388611_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003529 434.0
HFD3_k127_4388611_3 PFAM L-carnitine dehydratase bile acid-inducible protein F K07544,K07749 - 2.8.3.15,2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009383 393.0
HFD3_k127_4388611_4 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006281 274.0
HFD3_k127_4388611_5 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000007586 199.0
HFD3_k127_4388611_6 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000001958 164.0
HFD3_k127_4388611_7 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000000000000000052 150.0
HFD3_k127_4388611_8 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000005082 72.0
HFD3_k127_4405456_0 Glycosyltransferase family 20 K00697,K13057,K20436 - 2.4.1.15,2.4.1.245,2.4.1.347,2.5.1.135 2.2e-241 777.0
HFD3_k127_4405456_1 phosphorelay signal transduction system K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 524.0
HFD3_k127_4405456_2 Glycosyl hydrolases family 15 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 497.0
HFD3_k127_4405456_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 424.0
HFD3_k127_4405456_4 phosphoglycolate phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001486 273.0
HFD3_k127_4405456_5 Removes the phosphate from trehalose 6-phosphate to produce free trehalose - - - 0.0000000000000000000000000000000000000002248 165.0
HFD3_k127_4405456_7 Histidine kinase - - - 0.0000979 51.0
HFD3_k127_4426286_0 helicase K08282 - 2.7.11.1 3.474e-316 991.0
HFD3_k127_4426286_1 Flavin-binding monooxygenase-like K03379,K21730 - 1.14.13.160,1.14.13.22 3.434e-263 824.0
HFD3_k127_4426286_10 - - - - 0.000000000000000000000000001524 116.0
HFD3_k127_4426286_11 - - - - 0.0000000000000000000000001915 120.0
HFD3_k127_4426286_12 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000002489 117.0
HFD3_k127_4426286_14 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.000000000000000006295 84.0
HFD3_k127_4426286_16 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000006137 79.0
HFD3_k127_4426286_2 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K17228 - 1.14.14.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006522 588.0
HFD3_k127_4426286_3 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 312.0
HFD3_k127_4426286_4 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0000726,GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008833,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006807 286.0
HFD3_k127_4426286_5 Zinc finger SWIM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000007078 248.0
HFD3_k127_4426286_6 Oxidoreductase family, C-terminal alpha/beta domain K19181 - 1.1.1.292 0.000000000000000000000000000000000000000000001739 178.0
HFD3_k127_4426286_7 - - - - 0.000000000000000000000000000000001275 150.0
HFD3_k127_4426286_8 PFAM Cupin 2, conserved barrel - - - 0.00000000000000000000000000001192 121.0
HFD3_k127_4426286_9 Pectate lyase - - - 0.00000000000000000000000000005347 135.0
HFD3_k127_4431067_0 Phosphotriesterase K07048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 311.0
HFD3_k127_4431067_1 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000000000141 219.0
HFD3_k127_4431067_2 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000006085 122.0
HFD3_k127_4432826_0 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008053 563.0
HFD3_k127_4452055_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 5.141e-231 732.0
HFD3_k127_4452055_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 2.344e-215 697.0
HFD3_k127_4452055_10 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005766 291.0
HFD3_k127_4452055_11 Peptidase family S58 K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000002518 265.0
HFD3_k127_4452055_12 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000000000000001343 192.0
HFD3_k127_4452055_13 domain protein - - - 0.000000000000000000000000000000000000000000000000007683 196.0
HFD3_k127_4452055_14 chlorophyll binding K03640 - - 0.0000000000000000000000000000000000004451 143.0
HFD3_k127_4452055_15 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000001271 144.0
HFD3_k127_4452055_16 Protein of unknown function (DUF2914) - - - 0.0000000000000000000000000000002517 141.0
HFD3_k127_4452055_17 TIGRFAM DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.000000000000000000000000000003499 131.0
HFD3_k127_4452055_18 - - - - 0.00000000000000001793 89.0
HFD3_k127_4452055_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 1.076e-195 642.0
HFD3_k127_4452055_20 - - - - 0.0000000001145 72.0
HFD3_k127_4452055_3 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 546.0
HFD3_k127_4452055_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 395.0
HFD3_k127_4452055_5 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009545 362.0
HFD3_k127_4452055_6 AAA domain K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 308.0
HFD3_k127_4452055_7 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 293.0
HFD3_k127_4452055_8 Radical SAM domain protein K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002564 284.0
HFD3_k127_4452055_9 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003024 284.0
HFD3_k127_4452094_0 CarboxypepD_reg-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 401.0
HFD3_k127_4452094_1 Pfam:SusD K21572 - - 0.000000000000000000000000000000000000000000000000000000000006206 233.0
HFD3_k127_4452094_2 Domain of unknown function (DUF4112) - - - 0.000004661 55.0
HFD3_k127_4460211_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain K03520,K11177 - 1.17.1.4,1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006219 632.0
HFD3_k127_4460211_1 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 330.0
HFD3_k127_4460518_0 Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002837 256.0
HFD3_k127_4460518_1 'PFAM Taurine catabolism dioxygenase TauD, TfdA family' - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004601 260.0
HFD3_k127_4460518_2 membrane - - - 0.0000000000000000000000000000000000000001895 153.0
HFD3_k127_4460518_3 membrane - - - 0.00005055 56.0
HFD3_k127_4464838_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 501.0
HFD3_k127_4464838_1 transferase activity, transferring glycosyl groups K12996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003667 472.0
HFD3_k127_4464838_10 Transport permease protein K09688,K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 320.0
HFD3_k127_4464838_11 Sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 310.0
HFD3_k127_4464838_12 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006281 302.0
HFD3_k127_4464838_13 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000001224 286.0
HFD3_k127_4464838_14 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000001447 235.0
HFD3_k127_4464838_15 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000002117 235.0
HFD3_k127_4464838_16 glycosyl transferase family 2 K00786 - - 0.000000000000000000000000000000000000000000000000000000000006733 218.0
HFD3_k127_4464838_17 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000005429 218.0
HFD3_k127_4464838_18 - - - - 0.000000000000000000000000000000000000000000000000000000008369 212.0
HFD3_k127_4464838_19 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000107 221.0
HFD3_k127_4464838_2 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 461.0
HFD3_k127_4464838_20 Methionine biosynthesis protein MetW K18827 - 2.1.1.294,2.7.1.181 0.000000000000000000000000000000000000000000000000000000264 222.0
HFD3_k127_4464838_21 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000003308 201.0
HFD3_k127_4464838_22 macromolecule localization K09690 - - 0.00000000000000000000000000000000000000000000000008356 187.0
HFD3_k127_4464838_23 PFAM glycosyl transferase family 2 K20444 - - 0.000000000000000000000000000000000000000000000001613 183.0
HFD3_k127_4464838_24 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000003701 187.0
HFD3_k127_4464838_25 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000005172 174.0
HFD3_k127_4464838_27 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000007049 154.0
HFD3_k127_4464838_28 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000004331 135.0
HFD3_k127_4464838_29 polysaccharide biosynthetic process K03183,K15256 - 2.1.1.163,2.1.1.201 0.000000000000000000000003378 112.0
HFD3_k127_4464838_3 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 428.0
HFD3_k127_4464838_30 Glycosyl transferases group 1 K06338 - - 0.0000000000000000000003014 113.0
HFD3_k127_4464838_31 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000007904 113.0
HFD3_k127_4464838_32 Tetratricopeptide repeat - - - 0.0000000000000004864 93.0
HFD3_k127_4464838_33 methyltransferase - - - 0.00000000000005978 86.0
HFD3_k127_4464838_34 Mycolic acid cyclopropane synthetase - - - 0.000000000001122 81.0
HFD3_k127_4464838_35 ubiE/COQ5 methyltransferase family - - - 0.0000000005161 70.0
HFD3_k127_4464838_36 Methyltransferase type 12 - - - 0.000000003711 70.0
HFD3_k127_4464838_4 PFAM ABC transporter K01990,K09691,K09693 - 3.6.3.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 430.0
HFD3_k127_4464838_5 Aminotransferase class-III K01845,K07257,K21585 - 2.6.1.111,5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 405.0
HFD3_k127_4464838_6 DegT/DnrJ/EryC1/StrS aminotransferase family K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005958 364.0
HFD3_k127_4464838_7 ATPases associated with a variety of cellular activities K01990,K09689,K09691 - 3.6.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000369 328.0
HFD3_k127_4464838_8 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 341.0
HFD3_k127_4464838_9 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 306.0
HFD3_k127_4475478_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 1.227e-197 646.0
HFD3_k127_4475478_1 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000007043 194.0
HFD3_k127_4475478_2 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000007272 189.0
HFD3_k127_4475478_3 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000949 161.0
HFD3_k127_4475478_4 Carbon monoxide dehydrogenase subunit G (CoxG) - - - 0.0000000000000000000124 98.0
HFD3_k127_4485988_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 434.0
HFD3_k127_4485988_1 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009314 289.0
HFD3_k127_4485988_2 Histidine kinase K01768,K02482,K02660,K03406,K05874,K07315,K10819,K11525,K11617 - 2.7.13.3,3.1.3.3,4.6.1.1 0.0000000000000000000000000000000000000001954 167.0
HFD3_k127_4556019_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K04105,K04110 - 6.2.1.25,6.2.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000457 558.0
HFD3_k127_4556019_1 NMT1 THI5-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 324.0
HFD3_k127_4556019_2 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 301.0
HFD3_k127_4556019_3 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000001505 265.0
HFD3_k127_4571094_0 OPT oligopeptide transporter protein - - - 4.835e-195 630.0
HFD3_k127_4571094_1 thiamine pyrophosphate binding K12261 GO:0001561,GO:0003674,GO:0003824,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006605,GO:0006625,GO:0006629,GO:0006631,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0015031,GO:0015833,GO:0016042,GO:0016043,GO:0016054,GO:0016829,GO:0016830,GO:0019395,GO:0019752,GO:0019842,GO:0022607,GO:0030258,GO:0030976,GO:0031907,GO:0031974,GO:0032787,GO:0033036,GO:0033365,GO:0034440,GO:0034613,GO:0036094,GO:0042579,GO:0042802,GO:0042886,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046395,GO:0046907,GO:0048037,GO:0050662,GO:0051179,GO:0051234,GO:0051259,GO:0051641,GO:0051649,GO:0055114,GO:0065003,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072329,GO:0072594,GO:0072662,GO:0072663,GO:0097159,GO:1901363,GO:1901575,GO:1901681 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004214 576.0
HFD3_k127_4571094_10 - - - - 0.0000000000000000000000008995 122.0
HFD3_k127_4571094_2 belongs to the bacterial solute-binding protein 3 family K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 512.0
HFD3_k127_4571094_3 polar amino acid transport system K02028 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000711 443.0
HFD3_k127_4571094_4 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 381.0
HFD3_k127_4571094_5 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 368.0
HFD3_k127_4571094_6 Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate K07404 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 354.0
HFD3_k127_4571094_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000205 235.0
HFD3_k127_4571094_8 - - - - 0.0000000000000000000000000000021 129.0
HFD3_k127_4571094_9 PFAM amidohydrolase 2 - - - 0.0000000000000000000000000004825 115.0
HFD3_k127_4622859_0 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006095 279.0
HFD3_k127_4622859_1 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007091 267.0
HFD3_k127_4622859_2 PFAM Peptidase M11 gametolysin - - - 0.00000000000000000000000000000000000008593 152.0
HFD3_k127_4673949_0 X-Pro dipeptidyl-peptidase domain protein K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004065 463.0
HFD3_k127_4673949_1 Transcriptional regulator - - - 0.0000000001028 68.0
HFD3_k127_4680701_0 PFAM Methionine synthase, vitamin-B12 independent K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000004321 226.0
HFD3_k127_4680701_1 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000002454 211.0
HFD3_k127_4680701_2 YCII-related domain - - - 0.000000000000000000000000000000001288 134.0
HFD3_k127_4681126_0 Adenylate and Guanylate cyclase catalytic domain - - - 3.224e-260 842.0
HFD3_k127_4681126_1 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002726 561.0
HFD3_k127_4681126_10 NIPSNAP - - - 0.00000000000000000000000000001035 128.0
HFD3_k127_4681126_11 YCII-related domain - - - 0.000000000000000000000000001435 126.0
HFD3_k127_4681126_13 Oxidoreductase FAD-binding domain K00523,K00529,K02639,K16246 - 1.17.1.1,1.18.1.3 0.0000000000001015 76.0
HFD3_k127_4681126_14 bacterial-type flagellum-dependent cell motility - - - 0.00000000009315 66.0
HFD3_k127_4681126_15 Histidine kinase K07651 - 2.7.13.3 0.0003 53.0
HFD3_k127_4681126_2 Dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006193 380.0
HFD3_k127_4681126_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K00446 - 1.13.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005842 294.0
HFD3_k127_4681126_4 Alpha/beta hydrolase family K01055 - 3.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000002609 262.0
HFD3_k127_4681126_5 PEP-CTERM motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000017 270.0
HFD3_k127_4681126_6 COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000008717 231.0
HFD3_k127_4681126_7 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000003897 210.0
HFD3_k127_4681126_8 protein related to plant photosystem II stability assembly factor - - - 0.000000000000000000000000000000000000000000000001887 188.0
HFD3_k127_4681126_9 Histidine kinase K03406,K07673,K07675 - 2.7.13.3 0.00000000000000000000000000000000007283 150.0
HFD3_k127_4681471_0 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008237 430.0
HFD3_k127_4681471_1 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000531 257.0
HFD3_k127_4681471_10 AMP-binding enzyme C-terminal domain - - - 0.0005382 51.0
HFD3_k127_4681471_2 Pentapeptide repeats (9 copies) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001174 265.0
HFD3_k127_4681471_3 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000009803 235.0
HFD3_k127_4681471_4 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564 - 0.000000000000000000000000000000000000000000000001172 178.0
HFD3_k127_4681471_5 protein histidine kinase activity K01768,K02484,K07636,K10681,K10819,K18350,K20487 - 2.7.13.3,4.6.1.1 0.000000000000000000000000000000000000000000003176 178.0
HFD3_k127_4681471_6 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000002443 154.0
HFD3_k127_4681471_7 Adenylate cyclase - - - 0.00000000004058 76.0
HFD3_k127_4681471_8 Protein of unknown function (DUF507) K09804 - - 0.0000000001969 69.0
HFD3_k127_4681471_9 Protein of unknown function (DUF507) - - - 0.0000009727 54.0
HFD3_k127_4684035_0 DNA ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005761 598.0
HFD3_k127_4684035_1 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000002565 270.0
HFD3_k127_4684035_2 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000084 229.0
HFD3_k127_4684092_0 Squalene/phytoene synthase K00801,K02291,K10208 GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0016767,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576 2.5.1.21,2.5.1.32,2.5.1.96,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004914 370.0
HFD3_k127_4684092_1 PAC2 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000134 238.0
HFD3_k127_4684092_2 PFAM Peptidase M23 - - - 0.000000000000000000000000000000000000000000000002135 195.0
HFD3_k127_4684092_3 isomerase activity K06998 - 5.3.3.17 0.0000000000000000000000000000001559 142.0
HFD3_k127_4684092_4 - - - - 0.0000000000000003634 82.0
HFD3_k127_4696457_0 Tripartite tricarboxylate transporter TctA family K07793 - - 7.872e-214 674.0
HFD3_k127_4696457_1 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 597.0
HFD3_k127_4696457_2 Integral membrane protein TerC family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000001296 222.0
HFD3_k127_4696457_3 PFAM Bacterial regulatory proteins, gntR family K05799 - - 0.0000000000000000000000000000000000000000008578 175.0
HFD3_k127_4721723_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 6.127e-290 904.0
HFD3_k127_4722430_0 Drug exporters of the RND superfamily K06994,K07003,K20466,K20470 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0009273,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0040007,GO:0042546,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071554,GO:0071702,GO:0071766,GO:0071840,GO:0071944,GO:1901264 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003885 581.0
HFD3_k127_4722430_1 Formate/nitrite transporter K06212,K21993 - - 0.000000000000000000000003333 103.0
HFD3_k127_4722430_2 GH3 auxin-responsive promoter - - - 0.000000000000000000003835 102.0
HFD3_k127_4722430_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000728 99.0
HFD3_k127_4729753_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1357.0
HFD3_k127_4729753_1 Amidohydrolase family K01464 - 3.5.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 433.0
HFD3_k127_4729753_2 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007337 290.0
HFD3_k127_4729753_3 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000001982 214.0
HFD3_k127_4729753_4 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000003683 220.0
HFD3_k127_4729753_5 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000001914 209.0
HFD3_k127_4729753_6 Transcription elongation factor, N-terminal K03624 - - 0.0000000000000000000000000000000000000000008795 171.0
HFD3_k127_4729753_7 DNA-sulfur modification-associated - - - 0.00000000000000000000164 107.0
HFD3_k127_4729893_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 595.0
HFD3_k127_4729893_1 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 451.0
HFD3_k127_4729893_10 AsmA family K07289 - - 0.0000000000003046 83.0
HFD3_k127_4729893_2 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 420.0
HFD3_k127_4729893_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 307.0
HFD3_k127_4729893_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001237 287.0
HFD3_k127_4729893_5 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000006638 221.0
HFD3_k127_4729893_6 FKBP-type peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.00000000000000000000000000000000003418 144.0
HFD3_k127_4729893_7 Lysyl oxidase - - - 0.0000000000000000000000000003845 124.0
HFD3_k127_4729893_8 PAS fold - - - 0.0000000000000000000004403 100.0
HFD3_k127_4729893_9 php family - - - 0.0000000000000000006509 94.0
HFD3_k127_4733123_0 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 611.0
HFD3_k127_4733123_1 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K03520 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 566.0
HFD3_k127_4733123_2 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006173 264.0
HFD3_k127_4733123_3 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520,K11177 - 1.17.1.4,1.2.5.3 0.00000000000000000000000000000000000000000000000000000004659 218.0
HFD3_k127_4733123_4 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000000000000000000000004833 196.0
HFD3_k127_4736273_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.0 1048.0
HFD3_k127_4736273_1 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749,K14471,K14472 - 2.8.3.16,2.8.3.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008107 412.0
HFD3_k127_4736273_10 Protein of unknown function (DUF3024) - - - 0.00000000000000000000002095 104.0
HFD3_k127_4736273_11 -acetyltransferase - - - 0.000000000000000000008359 99.0
HFD3_k127_4736273_12 Methyltransferase domain - - - 0.0000000000000000000138 100.0
HFD3_k127_4736273_13 CHRD domain - - - 0.00000000000000000006549 97.0
HFD3_k127_4736273_14 Belongs to the 'phage' integrase family K14059 - - 0.000000937 60.0
HFD3_k127_4736273_15 Belongs to the 'phage' integrase family - - - 0.00001663 51.0
HFD3_k127_4736273_16 Glycosyl transferases group 1 - - - 0.00001739 51.0
HFD3_k127_4736273_2 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000837 379.0
HFD3_k127_4736273_3 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 298.0
HFD3_k127_4736273_4 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005327 278.0
HFD3_k127_4736273_5 PFAM FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006763 283.0
HFD3_k127_4736273_6 PFAM 6-phosphogluconate dehydrogenase NAD-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002506 252.0
HFD3_k127_4736273_7 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000001521 244.0
HFD3_k127_4736273_8 DinB superfamily - - - 0.00000000000000000000000000000000000000005423 160.0
HFD3_k127_4736273_9 Glyoxalase-like domain K08234 - - 0.0000000000000000000000000000000000000007319 153.0
HFD3_k127_4761849_0 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 1.918e-268 840.0
HFD3_k127_4761849_1 Amidase K02433 - 6.3.5.6,6.3.5.7 9.975e-201 635.0
HFD3_k127_4761849_10 Fatty acid desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002831 269.0
HFD3_k127_4761849_11 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate - - - 0.000000000000000000000000000000000000000000000000000000000000000005138 231.0
HFD3_k127_4761849_12 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000001088 252.0
HFD3_k127_4761849_13 two-component system sensor protein - - - 0.000000000000000000000000000000000000000000000001914 191.0
HFD3_k127_4761849_14 Aconitase family (aconitate hydratase) - - - 0.00000000000000000000000000000000000000000000004963 170.0
HFD3_k127_4761849_15 - - - - 0.000000000000000000000000000000000000000000001336 173.0
HFD3_k127_4761849_16 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000005828 159.0
HFD3_k127_4761849_17 Sigma-70, region 4 - - - 0.000000000000000000000000000000000000008521 155.0
HFD3_k127_4761849_18 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000006846 139.0
HFD3_k127_4761849_19 translation initiation inhibitor, yjgF family - - - 0.000000000000000000001972 108.0
HFD3_k127_4761849_2 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 547.0
HFD3_k127_4761849_20 Putative zinc-finger - - - 0.00000000000000000007083 100.0
HFD3_k127_4761849_21 Protein of unknown function (DUF998) - - - 0.000000000000000004779 97.0
HFD3_k127_4761849_3 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K21417 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000401 518.0
HFD3_k127_4761849_4 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006808 516.0
HFD3_k127_4761849_5 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 497.0
HFD3_k127_4761849_6 PFAM dehydrogenase E1 component K21416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006484 463.0
HFD3_k127_4761849_7 Catalytic domain of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 425.0
HFD3_k127_4761849_8 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 405.0
HFD3_k127_4761849_9 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 301.0
HFD3_k127_4773392_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006606 517.0
HFD3_k127_4773392_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 434.0
HFD3_k127_4773392_2 GlcNAc-PI de-N-acetylase K01463 - - 0.0000000000000000000000000000000000000000000000000000692 189.0
HFD3_k127_4773392_3 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000001228 119.0
HFD3_k127_4793484_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1031.0
HFD3_k127_4793484_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 574.0
HFD3_k127_4793484_10 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000003066 192.0
HFD3_k127_4793484_11 - - - - 0.0000000000000000000000000000000000000000000001489 173.0
HFD3_k127_4793484_12 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000002343 167.0
HFD3_k127_4793484_13 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000005441 167.0
HFD3_k127_4793484_14 C4-type zinc ribbon domain K07164,K22391 - 3.5.4.16 0.00000000000000000000000001623 119.0
HFD3_k127_4793484_15 - - - - 0.000000001921 68.0
HFD3_k127_4793484_16 - - - - 0.00000002713 57.0
HFD3_k127_4793484_17 Protein of unknown function (DUF721) - - - 0.000001584 57.0
HFD3_k127_4793484_2 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 446.0
HFD3_k127_4793484_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004464 421.0
HFD3_k127_4793484_4 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006628 381.0
HFD3_k127_4793484_5 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 379.0
HFD3_k127_4793484_6 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 347.0
HFD3_k127_4793484_7 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 320.0
HFD3_k127_4793484_8 Tetratricopeptide repeat K11935 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 314.0
HFD3_k127_4793484_9 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000002021 226.0
HFD3_k127_4803799_0 AMP-binding enzyme C-terminal domain K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 395.0
HFD3_k127_4803799_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002196 290.0
HFD3_k127_4803799_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000001217 172.0
HFD3_k127_4803799_3 Belongs to the mandelate racemase muconate lactonizing enzyme family K01684 - 4.2.1.6 0.0000000000000000000000000000001342 128.0
HFD3_k127_4803799_4 mandelate racemase muconate lactonizing K01781 - 5.1.2.2 0.000000000000000000000001693 112.0
HFD3_k127_4803799_5 - K11477 - - 0.00000000000000000000000427 106.0
HFD3_k127_4803799_6 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K03518 - 1.2.5.3 0.00000000004067 64.0
HFD3_k127_4824942_0 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006526 306.0
HFD3_k127_4824942_1 Belongs to the thiolase family K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000001227 269.0
HFD3_k127_4837463_0 L-carnitine dehydratase bile acid-inducible protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 542.0
HFD3_k127_4837463_1 mandelate racemase muconate lactonizing - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004619 537.0
HFD3_k127_4837463_10 PFAM short chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000007395 207.0
HFD3_k127_4837463_11 Catalyzes the conversion of maleate to fumarate K01799,K06033 - 4.1.1.76,5.2.1.1 0.000000000000000000000000000000003224 138.0
HFD3_k127_4837463_12 PFAM Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000003637 123.0
HFD3_k127_4837463_13 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.0000000000000000000000000001193 123.0
HFD3_k127_4837463_14 pyridoxamine 5'-phosphate K07005 - - 0.0000000000000000000000004643 115.0
HFD3_k127_4837463_15 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000897 105.0
HFD3_k127_4837463_16 Peptidase family M28 - - - 0.000000000000000001569 99.0
HFD3_k127_4837463_17 Extracellular solute-binding protein, family 5 K02035 - - 0.000006379 50.0
HFD3_k127_4837463_18 Protein of unknown function (DUF1706) - - - 0.0003295 51.0
HFD3_k127_4837463_2 phospholipase C K01114 - 3.1.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 545.0
HFD3_k127_4837463_3 COG3970 Fumarylacetoacetate (FAA) hydrolase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006572 479.0
HFD3_k127_4837463_4 Amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009206 334.0
HFD3_k127_4837463_5 Nitroreductase family K10678 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007053 342.0
HFD3_k127_4837463_6 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 319.0
HFD3_k127_4837463_7 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001877 266.0
HFD3_k127_4837463_8 Putative oxidoreductase C terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001314 256.0
HFD3_k127_4837463_9 COG1062 Zn-dependent alcohol dehydrogenases, class III K00001,K00121 - 1.1.1.1,1.1.1.284 0.00000000000000000000000000000000000000000000000000000000003144 209.0
HFD3_k127_4839633_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 422.0
HFD3_k127_4839633_1 MacB-like periplasmic core domain K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 422.0
HFD3_k127_4839633_2 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001791 284.0
HFD3_k127_484264_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 5.315e-268 844.0
HFD3_k127_484264_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 1.534e-249 789.0
HFD3_k127_484264_10 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 401.0
HFD3_k127_484264_11 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006632 315.0
HFD3_k127_484264_12 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 303.0
HFD3_k127_484264_13 ABC transporter K09689,K09691 - 3.6.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 290.0
HFD3_k127_484264_14 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000001788 246.0
HFD3_k127_484264_15 DHH family K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000009798 242.0
HFD3_k127_484264_16 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000001534 245.0
HFD3_k127_484264_17 - - - - 0.000000000000000000000000000000000000000000000000000000000000002257 231.0
HFD3_k127_484264_18 Transport permease protein K09688,K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000131 224.0
HFD3_k127_484264_19 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000001603 236.0
HFD3_k127_484264_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 4.07e-200 652.0
HFD3_k127_484264_20 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000003013 188.0
HFD3_k127_484264_21 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.000000000000000000000000000000000000000002051 164.0
HFD3_k127_484264_22 O-linked GlcNAc transferase - - - 0.000000000000000000000000000000003302 140.0
HFD3_k127_484264_23 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000001645 129.0
HFD3_k127_484264_24 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000007182 128.0
HFD3_k127_484264_25 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000001148 119.0
HFD3_k127_484264_26 Protein of unknown function (DUF503) K09764 - - 0.0000000000000000005488 89.0
HFD3_k127_484264_27 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000002334 89.0
HFD3_k127_484264_28 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000887 73.0
HFD3_k127_484264_29 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000008244 69.0
HFD3_k127_484264_3 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000754 619.0
HFD3_k127_484264_30 Protein of unknown function (DUF448) K07742 - - 0.00000000002112 71.0
HFD3_k127_484264_4 Glycosyltransferase, group 2 family protein K20444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 599.0
HFD3_k127_484264_5 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005507 564.0
HFD3_k127_484264_6 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 541.0
HFD3_k127_484264_7 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 541.0
HFD3_k127_484264_8 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 478.0
HFD3_k127_484264_9 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 409.0
HFD3_k127_4844739_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000006108 240.0
HFD3_k127_4844739_1 Putative MetA-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000006109 179.0
HFD3_k127_4844739_2 COG1484 DNA replication protein - - - 0.000000000000000001396 91.0
HFD3_k127_4844739_3 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 - - 0.000001086 54.0
HFD3_k127_486207_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 8.443e-304 946.0
HFD3_k127_486207_1 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008837 394.0
HFD3_k127_486207_2 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000625 327.0
HFD3_k127_486207_3 hydrolase of alkaline phosphatase superfamily K07014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000424 332.0
HFD3_k127_486207_4 60Kd inner membrane protein - - - 0.00000000000000000000000000004611 137.0
HFD3_k127_486207_5 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase K03217 - - 0.00000000000000000000000007843 114.0
HFD3_k127_4910026_0 COG1233 Phytoene dehydrogenase and related proteins - - - 1.62e-216 686.0
HFD3_k127_4910026_1 NADH dehydrogenase (ubiquinone) activity K14089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 530.0
HFD3_k127_4910026_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 516.0
HFD3_k127_4910026_3 Proton-conducting membrane transporter K12137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005667 506.0
HFD3_k127_4910026_4 Proton-conducting membrane transporter K12141 GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0033554,GO:0044425,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008403 419.0
HFD3_k127_4910026_5 Histidine kinase-like ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004433 355.0
HFD3_k127_4910026_6 NADH dehydrogenase K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 347.0
HFD3_k127_4910026_7 mannose-1-phosphate guanylyltransferase activity K00971,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000000192 216.0
HFD3_k127_4910026_8 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000002172 223.0
HFD3_k127_4910026_9 Hydrogenase 4 membrane K12140 GO:0008150,GO:0040007 - 0.0000000000000000000000000000000000005756 158.0
HFD3_k127_4915130_0 Protein of unknown function (DUF2867) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006459 606.0
HFD3_k127_4915130_1 Deoxyribodipyrimidine photo-lyase K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008221 610.0
HFD3_k127_4915130_10 Integrase core domain K07497 - - 0.000000000000000000000000000002198 133.0
HFD3_k127_4915130_11 transposition K07497 - - 0.000000000001423 71.0
HFD3_k127_4915130_12 Recombinase zinc beta ribbon domain - - - 0.0000001319 61.0
HFD3_k127_4915130_2 Potassium uptake protein K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 462.0
HFD3_k127_4915130_3 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 410.0
HFD3_k127_4915130_4 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 355.0
HFD3_k127_4915130_5 MULE transposase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000006805 244.0
HFD3_k127_4915130_6 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000002064 136.0
HFD3_k127_4915130_7 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000312 144.0
HFD3_k127_4915130_8 Belongs to the peptidase S14 family K01358 - 3.4.21.92 0.00000000000000000000000000000002443 144.0
HFD3_k127_4915130_9 peptidase K21471 - - 0.0000000000000000000000000000001575 134.0
HFD3_k127_4976131_0 Belongs to the LDH2 MDH2 oxidoreductase family K16844 - 1.1.1.338 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008951 403.0
HFD3_k127_4976131_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 394.0
HFD3_k127_4976131_10 Major facilitator superfamily - - - 0.000000000000000000000000000000289 138.0
HFD3_k127_4976131_2 Beta-lactamase class A K17836 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 310.0
HFD3_k127_4976131_3 NAD(P)-binding Rossmann-like domain K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007003 317.0
HFD3_k127_4976131_4 Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively K04099,K04101 - 1.13.11.57,1.13.11.8 0.000000000000000000000000000000000000000000000000000000006341 207.0
HFD3_k127_4976131_5 Enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000007015 184.0
HFD3_k127_4976131_6 dehydratase - - - 0.0000000000000000000000000000000000000000000326 165.0
HFD3_k127_4976131_7 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000004194 169.0
HFD3_k127_4976131_8 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000002899 160.0
HFD3_k127_4976131_9 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000001186 162.0
HFD3_k127_4986878_0 His Kinase A (phosphoacceptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 620.0
HFD3_k127_4986878_1 elongation factor SelB, winged helix K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007098 595.0
HFD3_k127_4986878_10 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000000000000000000003314 223.0
HFD3_k127_4986878_11 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000000000000000000000000000000000000000000001795 188.0
HFD3_k127_4986878_12 Protein of unknown function (DUF3105) - - - 0.000000000000000000000000000000000000000000002238 172.0
HFD3_k127_4986878_13 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000002558 171.0
HFD3_k127_4986878_14 Parallel beta-helix repeats K12287 - - 0.0000000000000000000000000000000000000000001385 181.0
HFD3_k127_4986878_15 ATP hydrolysis coupled proton transport - - - 0.0000000000000000000000000000000000359 154.0
HFD3_k127_4986878_16 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000005672 90.0
HFD3_k127_4986878_18 2-methylcitrate dehydratase activity - - - 0.00000000000000001751 87.0
HFD3_k127_4986878_19 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.000000000000002679 81.0
HFD3_k127_4986878_2 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006462 438.0
HFD3_k127_4986878_20 Sigma-54 factor interaction domain-containing protein K07713 - - 0.0000000000001601 78.0
HFD3_k127_4986878_21 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000001044 67.0
HFD3_k127_4986878_3 Bacterial extracellular solute-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004003 431.0
HFD3_k127_4986878_4 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 393.0
HFD3_k127_4986878_5 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 386.0
HFD3_k127_4986878_6 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 384.0
HFD3_k127_4986878_7 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 387.0
HFD3_k127_4986878_8 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 370.0
HFD3_k127_4986878_9 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000306 231.0
HFD3_k127_4988724_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009569 450.0
HFD3_k127_4988724_1 protein kinase activity - - - 0.0000000000000002021 80.0
HFD3_k127_500890_0 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 489.0
HFD3_k127_500890_1 COG0747 ABC-type dipeptide transport system, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009042 432.0
HFD3_k127_500890_2 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 368.0
HFD3_k127_500890_3 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 316.0
HFD3_k127_500890_4 ABC transporter permease K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006152 288.0
HFD3_k127_500890_5 Haem-degrading - - - 0.000000000000000000000000000000000000004928 154.0
HFD3_k127_5056694_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 1.584e-250 807.0
HFD3_k127_5056694_1 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008025 345.0
HFD3_k127_5056694_2 Predicted membrane protein (DUF2238) K08984 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005232 273.0
HFD3_k127_5056694_3 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000001899 270.0
HFD3_k127_5056694_4 Membrane K08984 - - 0.00000000000000000000000000000000000000000000000000000000007912 211.0
HFD3_k127_5056694_5 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.0000000000000000004866 91.0
HFD3_k127_5058557_0 protein conserved in bacteria K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000008363 159.0
HFD3_k127_5058557_1 PLD-like domain - - - 0.0000000000000000000000000000000005407 138.0
HFD3_k127_5058557_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000004293 103.0
HFD3_k127_50601_0 [glutamate-ammonia-ligase] adenylyltransferase activity K00982 GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 580.0
HFD3_k127_50601_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 495.0
HFD3_k127_50601_10 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000612 177.0
HFD3_k127_50601_11 phosphoglycerate mutase K02226 - 3.1.3.73 0.0000000000000000000000000001096 131.0
HFD3_k127_50601_12 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335,K03469 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7,3.1.26.4 0.000000000000000000000003141 113.0
HFD3_k127_50601_13 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0042759,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113 2.1.3.15,6.4.1.2 0.00000000000000000007141 89.0
HFD3_k127_50601_2 Starch synthase catalytic domain K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 459.0
HFD3_k127_50601_3 PFAM FAD linked oxidase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 385.0
HFD3_k127_50601_4 PFAM Na Picotransporter K03324 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006608 384.0
HFD3_k127_50601_5 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 348.0
HFD3_k127_50601_6 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005804 301.0
HFD3_k127_50601_7 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005096 297.0
HFD3_k127_50601_8 PFAM Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000179 287.0
HFD3_k127_50601_9 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000001007 240.0
HFD3_k127_5092161_0 PFAM Integrase catalytic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 538.0
HFD3_k127_5092161_1 PFAM IstB domain protein ATP-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005176 274.0
HFD3_k127_5092161_2 ATP dependent DNA ligase C terminal region - - - 0.0006441 47.0
HFD3_k127_5124235_0 Tetratricopeptide repeat K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 411.0
HFD3_k127_5130638_0 PFAM Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 458.0
HFD3_k127_5130638_1 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 467.0
HFD3_k127_5130638_2 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 369.0
HFD3_k127_5130638_3 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 318.0
HFD3_k127_5130638_4 Rieske [2Fe-2S] domain K19982 - - 0.0000000000000000000000000000000000000000000000001159 196.0
HFD3_k127_5130638_5 Rieske [2Fe-2S] domain K19982 - - 0.0000000000000000000000000000000000000000000000004093 188.0
HFD3_k127_5130638_6 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059,K00068,K03366 - 1.1.1.100,1.1.1.140,1.1.1.304,1.1.1.76 0.0000000000000000009461 89.0
HFD3_k127_5130638_7 - K09004 - - 0.0000000000000009697 87.0
HFD3_k127_5130638_8 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 0.0000000000001062 75.0
HFD3_k127_5130638_9 ABC-type Fe3 transport system permease component K02011 - - 0.00005975 54.0
HFD3_k127_5134071_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 503.0
HFD3_k127_5134071_1 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 451.0
HFD3_k127_5134071_10 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000001071 151.0
HFD3_k127_5134071_11 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000000000000000003434 146.0
HFD3_k127_5134071_12 MaoC like domain K17865 - 4.2.1.55 0.000000000002674 72.0
HFD3_k127_5134071_2 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009051 374.0
HFD3_k127_5134071_3 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 377.0
HFD3_k127_5134071_4 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 365.0
HFD3_k127_5134071_5 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005699 280.0
HFD3_k127_5134071_6 Monogalactosyldiacylglycerol (MGDG) synthase K03429 - 2.4.1.315 0.00000000000000000000000000000000000000000000000000000000000006479 233.0
HFD3_k127_5134071_7 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000007177 178.0
HFD3_k127_5134071_8 MaoC like domain - - - 0.0000000000000000000000000000000000000001076 155.0
HFD3_k127_5134071_9 xylanase chitin deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000000000000000002951 168.0
HFD3_k127_5135972_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1170.0
HFD3_k127_5135972_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009714 519.0
HFD3_k127_5135972_10 Belongs to the peptidase S11 family K01286 - 3.4.16.4 0.0000000000000000000000000000000000000000000000602 180.0
HFD3_k127_5135972_11 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000003344 89.0
HFD3_k127_5135972_12 - - - - 0.0000000000007625 72.0
HFD3_k127_5135972_13 - - - - 0.000000003617 63.0
HFD3_k127_5135972_14 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.00000001819 61.0
HFD3_k127_5135972_2 Gamma-glutamyltranspeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 359.0
HFD3_k127_5135972_3 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016020,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0040007,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007336 338.0
HFD3_k127_5135972_4 ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006305 348.0
HFD3_k127_5135972_5 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001497 260.0
HFD3_k127_5135972_6 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000003901 234.0
HFD3_k127_5135972_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000024 229.0
HFD3_k127_5135972_8 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000111 215.0
HFD3_k127_5135972_9 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000004273 208.0
HFD3_k127_5150942_0 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 511.0
HFD3_k127_5150942_1 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007055 534.0
HFD3_k127_5150942_10 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004733 296.0
HFD3_k127_5150942_11 ABC transporter K09817 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001333 268.0
HFD3_k127_5150942_12 L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000002225 263.0
HFD3_k127_5150942_13 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000005156 250.0
HFD3_k127_5150942_14 Inositol monophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000001477 230.0
HFD3_k127_5150942_15 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01781 - 5.1.2.2 0.00000000000000000000000000000000000000000000000000000000000002891 241.0
HFD3_k127_5150942_16 ABC-type Mn2 Zn2 transport K09816 - - 0.00000000000000000000000000000000000000000000000000000000001912 215.0
HFD3_k127_5150942_17 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025 - - 0.0000000000000000000000000000000000000000000000000000000001919 211.0
HFD3_k127_5150942_18 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000006057 190.0
HFD3_k127_5150942_19 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.000000000000000000000000000000000000000000000002112 198.0
HFD3_k127_5150942_2 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005769 516.0
HFD3_k127_5150942_20 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon K03709 - - 0.000000000000000000000000000000000000000000009914 186.0
HFD3_k127_5150942_21 Metallo-beta-lactamase superfamily K13075 - 3.1.1.81 0.00000000000000000000000000000000000000002996 161.0
HFD3_k127_5150942_22 bacterial-type flagellum-dependent cell motility - - - 0.00000000000000000000000000000000000002263 166.0
HFD3_k127_5150942_23 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.000000000000000000000000000000001165 134.0
HFD3_k127_5150942_24 Domain of Unknown Function (DUF748) - - - 0.0000000000000002385 95.0
HFD3_k127_5150942_25 Phosphoesterase, PA-phosphatase related K19302 - 3.6.1.27 0.0000000000001942 80.0
HFD3_k127_5150942_27 acr, cog1430 K09005 - - 0.000000001946 70.0
HFD3_k127_5150942_28 - - - - 0.000000002293 63.0
HFD3_k127_5150942_3 PFAM Cys Met metabolism pyridoxal-phosphate-dependent K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004575 469.0
HFD3_k127_5150942_4 alpha beta alpha domain I K01840,K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 445.0
HFD3_k127_5150942_5 acyl-CoA transferases carnitine dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007847 338.0
HFD3_k127_5150942_6 PFAM Copper resistance D K07245 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 341.0
HFD3_k127_5150942_7 cation diffusion facilitator family transporter K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007665 301.0
HFD3_k127_5150942_8 metal-dependent hydrolase of the TIM-barrel fold K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 315.0
HFD3_k127_5150942_9 Belongs to the bacterial solute-binding protein 9 family K09815,K09818 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002734 284.0
HFD3_k127_5166569_0 Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000000000000000002883 194.0
HFD3_k127_5166569_1 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000004857 135.0
HFD3_k127_5166569_2 Nucleotidyltransferase domain - - - 0.00000000001007 72.0
HFD3_k127_5166569_3 Protein of unknown function DUF86 - - - 0.000131 55.0
HFD3_k127_5180640_0 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000003644 246.0
HFD3_k127_5180640_1 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003949 252.0
HFD3_k127_5208416_0 signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007862 397.0
HFD3_k127_5208416_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 302.0
HFD3_k127_5208416_2 response regulator K02485 - - 0.0000000000000000000000000000000000000000000000000000003701 220.0
HFD3_k127_5208416_3 Belongs to the peptidase S1C family - - - 0.000000000000000000000000000000000000000000000000000001208 208.0
HFD3_k127_5208416_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000002256 136.0
HFD3_k127_5267892_0 PFAM D-galactarate dehydratase Altronate hydrolase K01685 - 4.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007796 590.0
HFD3_k127_5267892_1 OST-HTH/LOTUS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005451 377.0
HFD3_k127_5267892_10 Thioredoxin - - - 0.0000000000000000000000000000000001832 136.0
HFD3_k127_5267892_11 Cytochrome C biogenesis protein - - - 0.00000000000000000000000000000007943 126.0
HFD3_k127_5267892_12 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000000000000000000643 119.0
HFD3_k127_5267892_13 Redoxin - - - 0.000000002863 61.0
HFD3_k127_5267892_2 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 357.0
HFD3_k127_5267892_3 Belongs to the ABC transporter superfamily K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008273 351.0
HFD3_k127_5267892_4 PFAM binding-protein-dependent transport systems inner membrane component K02033,K12369,K13890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 293.0
HFD3_k127_5267892_5 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 289.0
HFD3_k127_5267892_6 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000281 269.0
HFD3_k127_5267892_7 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004191 266.0
HFD3_k127_5267892_8 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000004629 243.0
HFD3_k127_5267892_9 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000166 232.0
HFD3_k127_5285959_0 PFAM peptidase S9A prolyl oligopeptidase domain protein beta-propeller K01354 - 3.4.21.83 4.46e-237 769.0
HFD3_k127_5285959_1 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008977 565.0
HFD3_k127_5285959_2 Amidase K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005168 552.0
HFD3_k127_5285959_3 N-methylhydantoinase B acetone carboxylase, alpha subunit K01474 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008991 488.0
HFD3_k127_5285959_4 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007851 401.0
HFD3_k127_5285959_5 Phosphatidylinositol - - - 0.0000000000000000000000000000000000000000000000000000000000000000001691 245.0
HFD3_k127_5285959_6 Histidine phosphatase superfamily (branch 1) - - - 0.000000000000000000000000000000000000000000000000000000000000000001352 237.0
HFD3_k127_5285959_7 short-chain K00034,K00038,K00046 - 1.1.1.47,1.1.1.53,1.1.1.69 0.0000000000000000000000000000000000000000000000000000008396 209.0
HFD3_k127_5285959_8 Protein of unknown function (DUF3090) - - - 0.0000000000000000000000000000000000002441 146.0
HFD3_k127_5292405_0 Aconitase C-terminal domain K01681 - 4.2.1.3 0.0 1086.0
HFD3_k127_5292405_1 succinate dehydrogenase, flavoprotein subunit K00239 GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363 1.3.5.1,1.3.5.4 1.31e-288 909.0
HFD3_k127_5292405_10 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000002881 203.0
HFD3_k127_5292405_11 Histidine triad (Hit) protein K02503 - - 0.000000000000000000000000000000000000000000000000005078 193.0
HFD3_k127_5292405_12 2Fe-2S iron-sulfur cluster binding domain K00245 - 1.3.5.4 0.00000000000000000000000000000000000000000000000002999 186.0
HFD3_k127_5292405_13 Uncharacterised MFS-type transporter YbfB - - - 0.000000000000000000000000000000000002129 158.0
HFD3_k127_5292405_2 Converts isocitrate to alpha ketoglutarate K00031 - 1.1.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 605.0
HFD3_k127_5292405_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006037 477.0
HFD3_k127_5292405_4 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 433.0
HFD3_k127_5292405_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 415.0
HFD3_k127_5292405_6 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005312 387.0
HFD3_k127_5292405_7 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 349.0
HFD3_k127_5292405_8 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 310.0
HFD3_k127_5292405_9 subunit beta - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003302 246.0
HFD3_k127_5320886_0 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483 - 1.14.14.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 530.0
HFD3_k127_5320886_1 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 448.0
HFD3_k127_5320886_2 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 408.0
HFD3_k127_5320886_3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01872,K07050 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003668 310.0
HFD3_k127_5320886_4 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000003047 183.0
HFD3_k127_5320886_5 - - - - 0.0000000000000000000000000000000000000000001658 171.0
HFD3_k127_5320886_6 Haloacid dehalogenase-like hydrolase K07025,K18569 - - 0.000000000000001204 85.0
HFD3_k127_5320886_7 Methyltransferase type 12 - - - 0.000006996 57.0
HFD3_k127_5323542_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1018.0
HFD3_k127_5323542_1 PFAM ABC transporter K02471 - - 2.824e-216 688.0
HFD3_k127_5323542_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007426 447.0
HFD3_k127_5323542_3 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000003117 195.0
HFD3_k127_5323542_4 Sulfatase K01130 - 3.1.6.1 0.0000003559 55.0
HFD3_k127_5333187_0 4Fe-4S dicluster domain K00184 - - 4.091e-205 673.0
HFD3_k127_5333187_1 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 506.0
HFD3_k127_5333187_2 Pfam Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000001003 192.0
HFD3_k127_5333187_3 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000009618 139.0
HFD3_k127_5333187_4 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000000000000000000004741 114.0
HFD3_k127_5333187_5 cytochrome c - - - 0.000000000000000000003744 100.0
HFD3_k127_5394897_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 423.0
HFD3_k127_5394897_1 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009981 280.0
HFD3_k127_5399611_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1149.0
HFD3_k127_5399611_1 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 550.0
HFD3_k127_5399611_10 NADP oxidoreductase, coenzyme f420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000002592 203.0
HFD3_k127_5399611_12 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.00000000000000000000000000000000000000014 174.0
HFD3_k127_5399611_13 Belongs to the mandelate racemase muconate lactonizing enzyme family K01684 - 4.2.1.6 0.0000000000000000000000000000000003542 134.0
HFD3_k127_5399611_14 phosphatidate phosphatase activity - - - 0.00000000000000002647 93.0
HFD3_k127_5399611_15 acetyltransferase K00661 - 2.3.1.79 0.00000000000000002674 89.0
HFD3_k127_5399611_16 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0000000000000124 86.0
HFD3_k127_5399611_17 Sulfatase K01130 - 3.1.6.1 0.0000000000001017 76.0
HFD3_k127_5399611_18 dehydratase - - - 0.000000002022 68.0
HFD3_k127_5399611_19 protein localization to T-tubule K10380,K15502 - - 0.000034 54.0
HFD3_k127_5399611_2 ATP ADP translocase K03301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 503.0
HFD3_k127_5399611_20 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000955 49.0
HFD3_k127_5399611_3 Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005651 444.0
HFD3_k127_5399611_4 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 413.0
HFD3_k127_5399611_5 Thiamine pyrophosphate enzyme, central domain K01576 - 4.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003999 327.0
HFD3_k127_5399611_6 PFAM PKD domain containing protein K11751 - 3.1.3.5,3.6.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005952 308.0
HFD3_k127_5399611_7 CO dehydrogenase flavoprotein C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008209 285.0
HFD3_k127_5399611_8 Protein of unknown function (DUF3225) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008834 258.0
HFD3_k127_5399611_9 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000002289 237.0
HFD3_k127_543029_0 Adenylate and Guanylate cyclase catalytic domain - - - 6.975e-285 905.0
HFD3_k127_543029_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 544.0
HFD3_k127_543029_2 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078,K05553 - - 0.00000000000000002249 88.0
HFD3_k127_5437833_0 mandelate racemase muconate lactonizing K01856,K02549 - 4.2.1.113,5.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008145 321.0
HFD3_k127_5437833_1 Alkylmercury lyase - - - 0.0000000000000000000000000000000000004438 146.0
HFD3_k127_5437833_3 - - - - 0.00002855 51.0
HFD3_k127_5453897_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 1.086e-229 722.0
HFD3_k127_5453897_1 3-demethylubiquinone-9 3-O-methyltransferase activity K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 457.0
HFD3_k127_5453897_10 Nucleotidyl transferase - - - 0.000000000000000000000000000000000000000000001058 177.0
HFD3_k127_5453897_11 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.0000000000000000000000000000000000006772 151.0
HFD3_k127_5453897_12 Rhodanese Homology Domain - - - 0.00000000000000000000002418 104.0
HFD3_k127_5453897_13 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000005493 106.0
HFD3_k127_5453897_14 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00992 - 2.7.7.99 0.0000000001472 73.0
HFD3_k127_5453897_15 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.000007653 50.0
HFD3_k127_5453897_16 of the major facilitator superfamily K08151 - - 0.0001217 54.0
HFD3_k127_5453897_2 Sulfotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 389.0
HFD3_k127_5453897_3 Copper resistance K07245 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009457 339.0
HFD3_k127_5453897_4 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001383 281.0
HFD3_k127_5453897_5 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001017 278.0
HFD3_k127_5453897_6 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K11072 - 3.6.3.30,3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000003225 261.0
HFD3_k127_5453897_7 alpha amylase, catalytic region - - - 0.00000000000000000000000000000000000000000000000000000000000197 211.0
HFD3_k127_5453897_8 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000005345 198.0
HFD3_k127_5453897_9 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.00000000000000000000000000000000000000000000005013 179.0
HFD3_k127_5455103_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 394.0
HFD3_k127_5470402_0 regulatory protein, gntR - - - 0.00000000000000000000000000000000000000000000000000000000000000001279 240.0
HFD3_k127_5470402_1 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000001223 112.0
HFD3_k127_5470402_2 PFAM CBS domain containing protein K04767 - - 0.000000000001589 80.0
HFD3_k127_5470402_3 Outer membrane lipoprotein - - - 0.000000001048 71.0
HFD3_k127_5471341_0 Aminotransferase K11358 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 441.0
HFD3_k127_5471341_1 Selenoprotein B, glycine betaine sarcosine D-proline reductase family K10672 - 1.21.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008847 302.0
HFD3_k127_5471341_2 COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006321 286.0
HFD3_k127_5471341_3 PFAM Glycine sarcosine betaine reductase complex, protein B, alpha and beta subunits K10671 - 1.21.4.2 0.00000000000000000000000000000000000000000000000000000001752 212.0
HFD3_k127_5471341_4 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10672 - 1.21.4.2 0.00000000000000000001075 94.0
HFD3_k127_5480769_0 DEAD/H associated K03724 - - 0.0 1146.0
HFD3_k127_5480769_1 YbaK prolyl-tRNA synthetase associated region - - - 0.000000000000000000000000000000000000001745 153.0
HFD3_k127_5485873_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 2.441e-270 853.0
HFD3_k127_5485873_1 COG0526, thiol-disulfide isomerase and thioredoxins - - - 1.113e-198 627.0
HFD3_k127_5485873_10 - - - - 0.00000000000000000000000000008754 125.0
HFD3_k127_5485873_11 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000003992 100.0
HFD3_k127_5485873_12 Alpha/beta hydrolase family - - - 0.00000000000001168 78.0
HFD3_k127_5485873_13 alpha/beta hydrolase fold K01259 - 3.4.11.5 0.000000000001478 69.0
HFD3_k127_5485873_14 BlaR1 peptidase M56 - - - 0.0001439 56.0
HFD3_k127_5485873_2 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 2.068e-198 644.0
HFD3_k127_5485873_3 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00015 - 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 378.0
HFD3_k127_5485873_4 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 338.0
HFD3_k127_5485873_5 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006174 284.0
HFD3_k127_5485873_6 Nitronate monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002717 261.0
HFD3_k127_5485873_7 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000000000000000000000000000000000000000004706 189.0
HFD3_k127_5485873_8 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000003427 142.0
HFD3_k127_5485873_9 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000001231 122.0
HFD3_k127_5488015_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 392.0
HFD3_k127_5488015_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000003211 79.0
HFD3_k127_5496936_0 PFAM glycosyl transferase family 35 K00688 - 2.4.1.1 0.0 1100.0
HFD3_k127_5496936_1 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 1.031e-265 858.0
HFD3_k127_5496936_10 - - - - 0.000000000000001748 81.0
HFD3_k127_5496936_11 oxidoreductase - - - 0.0001527 46.0
HFD3_k127_5496936_2 Exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 519.0
HFD3_k127_5496936_3 Bacterial capsule synthesis protein PGA_cap - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004816 446.0
HFD3_k127_5496936_4 PFAM Sodium sulphate symporter K14445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005073 416.0
HFD3_k127_5496936_5 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009975,GO:0016874,GO:0016886,GO:0044424,GO:0044464,GO:0140098 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000007034 264.0
HFD3_k127_5496936_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000001258 225.0
HFD3_k127_5496936_7 Glycine-zipper domain - - - 0.0000000000000000000000000000001798 135.0
HFD3_k127_5496936_8 Domain of unknown function (DUF4437) - - - 0.000000000000000000000004738 108.0
HFD3_k127_55052_0 PQQ-like domain - - - 8.993e-250 782.0
HFD3_k127_55052_1 PFAM ABC transporter K02471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000673 549.0
HFD3_k127_55052_2 Bacterial periplasmic substrate-binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006728 254.0
HFD3_k127_55052_3 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000001243 216.0
HFD3_k127_55052_4 polysaccharide catabolic process K03478 - 3.5.1.105 0.00000000000000000000000000000000000004892 154.0
HFD3_k127_55052_5 metal ion transmembrane transporter activity - - - 0.000000000000002603 78.0
HFD3_k127_55052_6 COG1680 Beta-lactamase class C and other penicillin binding - - - 0.000002905 53.0
HFD3_k127_5508381_0 xanthine dehydrogenase activity K04108 - 1.3.7.9 0.0 1023.0
HFD3_k127_5508381_1 Enoyl-CoA hydratase/isomerase - - - 3.527e-240 753.0
HFD3_k127_5508381_2 benzoyl-CoA oxygenase - - - 2.346e-233 729.0
HFD3_k127_5508381_3 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K04105,K04110 - 6.2.1.25,6.2.1.27 6.861e-220 698.0
HFD3_k127_5508381_4 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000957 470.0
HFD3_k127_5508381_5 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000616 388.0
HFD3_k127_5508381_6 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 374.0
HFD3_k127_5508381_7 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000698 236.0
HFD3_k127_5508381_8 Cupin domain - - - 0.0000000000000000605 90.0
HFD3_k127_5535196_0 lipopolysaccharide transport K22110 - - 0.0 1290.0
HFD3_k127_5535196_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 1.228e-198 633.0
HFD3_k127_5535196_2 cellular water homeostasis K03442,K22044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001604 286.0
HFD3_k127_5535196_3 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K00851,K00852,K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 2.7.1.12,2.7.1.15,5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000004747 250.0
HFD3_k127_5535196_4 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000846 252.0
HFD3_k127_5535196_5 - - - - 0.000000000000000000000000000000000000000000000129 178.0
HFD3_k127_5535196_6 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000000000000000000006201 177.0
HFD3_k127_5535196_7 Putative zinc-finger - - - 0.0000000008167 68.0
HFD3_k127_5545031_0 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005 397.0
HFD3_k127_5545031_1 PFAM Methionine synthase, vitamin-B12 independent K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 357.0
HFD3_k127_5545031_2 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 324.0
HFD3_k127_5545031_3 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 336.0
HFD3_k127_5545031_4 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002256 289.0
HFD3_k127_5545031_5 P-loop containing region of AAA domain K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006132 288.0
HFD3_k127_5545031_6 PFAM luciferase-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000994 237.0
HFD3_k127_5545031_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000001792 220.0
HFD3_k127_5545031_8 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000002783 220.0
HFD3_k127_5545031_9 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000000000000000001592 90.0
HFD3_k127_5553532_0 Transport of potassium into the cell K03549 - - 1.428e-212 679.0
HFD3_k127_5553532_1 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000086 616.0
HFD3_k127_5553532_10 short-chain dehydrogenase reductase SDR K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 345.0
HFD3_k127_5553532_11 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 356.0
HFD3_k127_5553532_12 Receptor family ligand binding region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008157 342.0
HFD3_k127_5553532_13 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 321.0
HFD3_k127_5553532_14 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 346.0
HFD3_k127_5553532_15 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009808 332.0
HFD3_k127_5553532_16 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 306.0
HFD3_k127_5553532_17 ABC-type dipeptide oligopeptide nickel transport systems, permease components K15585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 305.0
HFD3_k127_5553532_18 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008808 308.0
HFD3_k127_5553532_19 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002444 287.0
HFD3_k127_5553532_2 Receptor family ligand binding region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 472.0
HFD3_k127_5553532_20 Zn-dependent hydrolases of the beta-lactamase fold K13985 - 3.1.4.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000001204 274.0
HFD3_k127_5553532_21 Cell division protein ZipA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001743 262.0
HFD3_k127_5553532_22 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002658 267.0
HFD3_k127_5553532_23 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000654 260.0
HFD3_k127_5553532_24 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002337 259.0
HFD3_k127_5553532_25 COG4177 ABC-type branched-chain amino acid transport system, permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001241 272.0
HFD3_k127_5553532_26 Belongs to the peptidase M16 family K07263 - - 0.000000000000000000000000000000000000000000000000000000000000002443 235.0
HFD3_k127_5553532_27 PFAM Peptidase M16 inactive domain - - - 0.00000000000000000000000000000000000000000000000000000000002786 233.0
HFD3_k127_5553532_28 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000007793 216.0
HFD3_k127_5553532_29 Belongs to the helicase family. UvrD subfamily - - - 0.0000000000000000000000000000000000000000000000000000000003414 214.0
HFD3_k127_5553532_3 MlrC C-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 418.0
HFD3_k127_5553532_30 KR domain - - - 0.000000000000000000000000000000000000000000000006561 195.0
HFD3_k127_5553532_31 HAD-hyrolase-like K07025 - - 0.000000000000000000000000000000000000000001898 176.0
HFD3_k127_5553532_32 translation release factor activity K03265 - - 0.0000000000000000000000000000000000000001309 168.0
HFD3_k127_5553532_33 HAD-hyrolase-like - - - 0.00000000000000000000000000000000000001203 154.0
HFD3_k127_5553532_34 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000000000008956 143.0
HFD3_k127_5553532_35 Protein of unknown function (DUF1054) - - - 0.0000000000000000000000000000000000006858 149.0
HFD3_k127_5553532_36 Thiopurine S-methyltransferase K00569 - 2.1.1.67 0.000000000000000000000000000000000001868 154.0
HFD3_k127_5553532_37 Protein of unknown function (DUF3047) - - - 0.00000000000000000000000000143 122.0
HFD3_k127_5553532_38 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000008555 115.0
HFD3_k127_5553532_39 Tautomerase enzyme K01821 - 5.3.2.6 0.00000000000000004641 85.0
HFD3_k127_5553532_4 AMP-binding enzyme C-terminal domain K16876 - 6.2.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005772 416.0
HFD3_k127_5553532_40 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000009702 70.0
HFD3_k127_5553532_41 regulation of translation K05808 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.0003772 48.0
HFD3_k127_5553532_5 transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 391.0
HFD3_k127_5553532_6 Extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008845 379.0
HFD3_k127_5553532_7 gluconolactonase K01053,K14274 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 362.0
HFD3_k127_5553532_8 Phospholipase D Transphosphatidylase K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000713 367.0
HFD3_k127_5553532_9 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 346.0
HFD3_k127_5559125_0 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 441.0
HFD3_k127_5559125_1 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007038 440.0
HFD3_k127_5559125_10 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000426 116.0
HFD3_k127_5559125_11 COGs COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family - - - 0.00000000000000000000002968 116.0
HFD3_k127_5559125_12 TIGRFAM pseudaminic acid biosynthesis-associated protein PseG - - - 0.00000000000000000000003724 116.0
HFD3_k127_5559125_13 Acetyltransferase (GNAT) domain - - - 0.000000000000001062 91.0
HFD3_k127_5559125_2 acid synthase K01654 - 2.5.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 424.0
HFD3_k127_5559125_3 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 333.0
HFD3_k127_5559125_4 PFAM ABC transporter transmembrane region K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 347.0
HFD3_k127_5559125_5 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 300.0
HFD3_k127_5559125_6 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000001025 225.0
HFD3_k127_5559125_7 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000009147 212.0
HFD3_k127_5559125_8 PFAM acylneuraminate cytidylyltransferase K07257 - - 0.0000000000000000000000000000000000000000000000000000000001182 214.0
HFD3_k127_5559125_9 Winged helix-turn-helix DNA-binding - - - 0.000000000000000000000000000008284 126.0
HFD3_k127_5580142_0 PFAM ABC transporter K01990,K13926 - - 0.0 1381.0
HFD3_k127_5580142_1 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 527.0
HFD3_k127_5580142_2 secretion protein K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 325.0
HFD3_k127_5580142_3 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000005416 210.0
HFD3_k127_5580142_4 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000005869 176.0
HFD3_k127_5617325_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1122.0
HFD3_k127_5617325_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 1.772e-202 632.0
HFD3_k127_5617325_10 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01684 - 4.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 402.0
HFD3_k127_5617325_11 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006205 370.0
HFD3_k127_5617325_12 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009591 259.0
HFD3_k127_5617325_13 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000000000000000008158 238.0
HFD3_k127_5617325_14 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000003747 202.0
HFD3_k127_5617325_15 Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively K04101 - 1.13.11.8 0.0000000000000000000000000000000000000000000000003984 186.0
HFD3_k127_5617325_16 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.0000000000000000000000000000000000000001063 174.0
HFD3_k127_5617325_17 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000004454 109.0
HFD3_k127_5617325_19 - - - - 0.0000009809 60.0
HFD3_k127_5617325_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 566.0
HFD3_k127_5617325_3 Iron permease FTR1 K07243 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006822 563.0
HFD3_k127_5617325_4 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009051 503.0
HFD3_k127_5617325_5 Amidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 491.0
HFD3_k127_5617325_6 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009949 481.0
HFD3_k127_5617325_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 487.0
HFD3_k127_5617325_8 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 422.0
HFD3_k127_5617325_9 4-phosphoerythronate dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008555 407.0
HFD3_k127_5624223_0 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 8.421e-207 651.0
HFD3_k127_5624223_1 PFAM SMP-30 Gluconolaconase K01053 - 3.1.1.17 3.178e-205 641.0
HFD3_k127_5624223_10 heat shock protein binding K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 316.0
HFD3_k127_5624223_11 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 312.0
HFD3_k127_5624223_12 PFAM PDZ domain (Also known as DHR or GLGF) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006189 308.0
HFD3_k127_5624223_13 Arsenical pump-driving ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 313.0
HFD3_k127_5624223_14 Bifunctional DNA primase/polymerase, N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 305.0
HFD3_k127_5624223_15 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000224 252.0
HFD3_k127_5624223_16 carbohydrate transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005655 256.0
HFD3_k127_5624223_18 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000002575 232.0
HFD3_k127_5624223_19 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.00000000000000000000000000000000000000000000000000000000000008872 232.0
HFD3_k127_5624223_2 Amidohydrolase family K01485 - 3.5.4.1 6.193e-198 624.0
HFD3_k127_5624223_20 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000007376 231.0
HFD3_k127_5624223_21 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000106 210.0
HFD3_k127_5624223_22 PFAM binding-protein-dependent transport systems inner membrane component K02025,K10237 - - 0.0000000000000000000000000000000000000000000000000000001077 207.0
HFD3_k127_5624223_23 ABC-type sugar transport system, permease component K02026,K17323 - - 0.0000000000000000000000000000000000000000000000000001185 207.0
HFD3_k127_5624223_24 Rhomboid family K19225 - 3.4.21.105 0.0000000000000000000000000000000000000000000000000003609 194.0
HFD3_k127_5624223_25 TIM-barrel fold metal-dependent hydrolase - - - 0.000000000000000000000000000000000000000000000000006272 203.0
HFD3_k127_5624223_26 Protein of unknown function (DUF1566) - - - 0.000000000000000000000000000000000000000000000009302 188.0
HFD3_k127_5624223_27 Destroys radicals which are normally produced within the cells and which are toxic to biological systems - - - 0.00000000000000000000000000000000000000000006012 167.0
HFD3_k127_5624223_28 Serine threonine protein kinase K08282 - 2.7.11.1 0.00000000000000000000000000000000000000002003 167.0
HFD3_k127_5624223_29 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000001102 169.0
HFD3_k127_5624223_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 629.0
HFD3_k127_5624223_30 PFAM Rhomboid family protein - - - 0.0000000000000000000000000000000000000279 160.0
HFD3_k127_5624223_31 Trypsin-like peptidase domain - - - 0.0000000000000000000000000000000000002976 154.0
HFD3_k127_5624223_32 Amidohydrolase K03392 - 4.1.1.45 0.0000000000000000000000000000000000006601 144.0
HFD3_k127_5624223_33 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000001305 138.0
HFD3_k127_5624223_34 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000001255 130.0
HFD3_k127_5624223_35 Amidohydrolase K03392,K22213 - 4.1.1.45,4.1.1.52 0.00000000000000000000000000000004251 131.0
HFD3_k127_5624223_36 pyridoxamine 5-phosphate - - - 0.0000000000000000000000000000004661 130.0
HFD3_k127_5624223_37 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000186 129.0
HFD3_k127_5624223_38 Gas vesicle synthesis protein GvpL/GvpF - - - 0.00000000000000000000000000000884 133.0
HFD3_k127_5624223_39 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.000000000000000000000000002346 127.0
HFD3_k127_5624223_4 Sodium Bile acid symporter family K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 550.0
HFD3_k127_5624223_40 Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure - - - 0.000000000000000000000000004045 114.0
HFD3_k127_5624223_41 Gas vesicle protein K - - - 0.00000000000000000000001997 108.0
HFD3_k127_5624223_42 Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth - - - 0.00000000000000000000002095 104.0
HFD3_k127_5624223_43 acyl-CoA dehydrogenase K22027 - 1.14.13.235 0.000000000000000005702 93.0
HFD3_k127_5624223_44 nuclease activity K06218 - - 0.0000000000000001637 82.0
HFD3_k127_5624223_45 Pfam:Pyridox_oxidase - - - 0.000000000000000523 87.0
HFD3_k127_5624223_47 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000006868 78.0
HFD3_k127_5624223_49 Thioesterase superfamily - - - 0.000000000002422 79.0
HFD3_k127_5624223_5 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 529.0
HFD3_k127_5624223_50 Protein of unknown function (DUF664) - - - 0.00000000002599 75.0
HFD3_k127_5624223_51 Gas vesicle - - - 0.0000000003854 72.0
HFD3_k127_5624223_52 Uncharacterized ACR, COG1993 K09137 - - 0.00000006674 57.0
HFD3_k127_5624223_54 Domain of unknown function (DUF4442) - - - 0.000007821 58.0
HFD3_k127_5624223_55 Right handed beta helix region - - - 0.00001007 59.0
HFD3_k127_5624223_6 monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009322 518.0
HFD3_k127_5624223_7 Methionine synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 485.0
HFD3_k127_5624223_8 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 475.0
HFD3_k127_5624223_9 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006332 383.0
HFD3_k127_5635454_0 Phosphoenolpyruvate phosphomutase K01637 - 4.1.3.1 4.222e-267 827.0
HFD3_k127_5635454_1 Belongs to the sigma-70 factor family - - - 2.04e-218 683.0
HFD3_k127_5635454_2 bifunctional deaminase-reductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001696 267.0
HFD3_k127_5635454_3 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000000000000000000003377 223.0
HFD3_k127_5635454_5 Transposase - - - 0.0000000000004547 74.0
HFD3_k127_5635454_6 GYD domain - - - 0.000001783 52.0
HFD3_k127_5640219_0 peptidase activity, acting on L-amino acid peptides K07004,K09955,K12567,K21449 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000001663 212.0
HFD3_k127_5640338_0 Arylsulfatase K01130 - 3.1.6.1 0.0 1405.0
HFD3_k127_5640338_1 Cytochrome c554 and c-prime - - - 7.089e-230 738.0
HFD3_k127_5640338_10 ABC-type transport auxiliary lipoprotein component - - - 0.0000000000000000000000000000000000000000000000003474 200.0
HFD3_k127_5640338_11 - - - - 0.0000000000000000000000000000000000000000000004718 171.0
HFD3_k127_5640338_12 - - - - 0.000000000000000000000000000000000000000000001758 181.0
HFD3_k127_5640338_13 PFAM extracellular solute-binding protein family 3 K02030,K09969,K10001 - - 0.00000000000000000000000000000007345 136.0
HFD3_k127_5640338_14 cheY-homologous receiver domain - - - 0.00000000000000000000000036 110.0
HFD3_k127_5640338_15 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000003031 87.0
HFD3_k127_5640338_2 MlaD protein K06192 - - 8.274e-211 670.0
HFD3_k127_5640338_3 Carbohydrate-selective porin, OprB family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007814 497.0
HFD3_k127_5640338_4 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000088 386.0
HFD3_k127_5640338_5 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 401.0
HFD3_k127_5640338_6 Trypsin-like serine protease K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 303.0
HFD3_k127_5640338_7 overlaps another CDS with the same product name - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 301.0
HFD3_k127_5640338_8 overlaps another CDS with the same product name - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003416 256.0
HFD3_k127_5640338_9 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000002379 226.0
HFD3_k127_5647366_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 553.0
HFD3_k127_5647366_1 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001392 253.0
HFD3_k127_5647366_2 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000183 206.0
HFD3_k127_5647366_3 FR47-like protein K03829 - - 0.0000000000000000000000000000000000000000000000000000001878 198.0
HFD3_k127_5647366_4 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000003037 160.0
HFD3_k127_5647366_5 Glycine-zipper domain - - - 0.000000000001244 76.0
HFD3_k127_5647366_7 - - - - 0.0000008643 60.0
HFD3_k127_5647366_8 Protein tyrosine kinase - - - 0.000004959 59.0
HFD3_k127_5654096_0 Dehydrogenase E1 component K21416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007908 351.0
HFD3_k127_5654096_1 PFAM Transketolase K21417 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 308.0
HFD3_k127_5654096_10 - - - - 0.0000000006856 66.0
HFD3_k127_5654096_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001197 267.0
HFD3_k127_5654096_3 Receptor family ligand binding region family protein 22 K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007025 253.0
HFD3_k127_5654096_4 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000001032 252.0
HFD3_k127_5654096_5 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000001179 252.0
HFD3_k127_5654096_6 Belongs to the binding-protein-dependent transport system permease family - - - 0.0000000000000000000000000000000009545 147.0
HFD3_k127_5654096_7 Domain of unknown function (DUF427) - - - 0.000000000000000000000000000002664 124.0
HFD3_k127_5654096_8 L-phenylalanine transmembrane transporter activity K01998 - - 0.00000000000000000000000000001916 122.0
HFD3_k127_5654096_9 PFAM translation initiation factor SUI1 K03113 - - 0.0000000000000000000000004881 108.0
HFD3_k127_5654954_0 Hydantoinase/oxoprolinase - - - 1.97e-278 874.0
HFD3_k127_5654954_1 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 553.0
HFD3_k127_5654954_2 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.00003383 49.0
HFD3_k127_5667825_0 Fibronectin type 3 domain - - - 0.00000000000000000000000000000000000000000001292 184.0
HFD3_k127_5667825_1 Aminotransferase class I and II K10907 - - 0.0000001026 58.0
HFD3_k127_5671938_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695,K03696 - - 0.0 1142.0
HFD3_k127_5671938_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.48e-213 679.0
HFD3_k127_5671938_2 DinB superfamily K18912 - 1.14.99.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 415.0
HFD3_k127_5671938_3 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004105 413.0
HFD3_k127_5671938_4 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007208 414.0
HFD3_k127_5671938_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 311.0
HFD3_k127_5671938_6 Histidine-specific methyltransferase, SAM-dependent K18911 - 2.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006957 295.0
HFD3_k127_5671938_7 abc transporter atp-binding protein K05847 - - 0.000000000000000000000000000000000000000000009269 165.0
HFD3_k127_5707309_0 Belongs to the transketolase family K00163 - 1.2.4.1 6.896e-232 742.0
HFD3_k127_5707309_1 Belongs to the IlvD Edd family - - - 3.916e-224 709.0
HFD3_k127_5707309_2 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 499.0
HFD3_k127_5707309_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003903 281.0
HFD3_k127_5707309_4 CoA-transferase family III K18702 - 2.8.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000002379 274.0
HFD3_k127_5707309_5 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001787 261.0
HFD3_k127_5707309_6 ThiJ PfpI - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005239 256.0
HFD3_k127_5707309_8 Glycine D-amino acid K00285 - 1.4.5.1 0.0001189 50.0
HFD3_k127_5714165_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 2e-248 777.0
HFD3_k127_5714165_1 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 608.0
HFD3_k127_5714165_2 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004171 387.0
HFD3_k127_5714165_3 Cation transport ATPase (P-type) K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000772 366.0
HFD3_k127_5714165_4 CBS domain K04767 - - 0.00000000000000000000000000000006482 138.0
HFD3_k127_5714165_5 IMP dehydrogenase activity K04767 - - 0.000000000000000000001063 107.0
HFD3_k127_5714165_6 Acetamidase/Formamidase family - - - 0.0000000000001542 73.0
HFD3_k127_5764424_0 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 563.0
HFD3_k127_5764424_1 Belongs to the ALAD family K01698 GO:0000287,GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 503.0
HFD3_k127_5764424_10 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000001016 218.0
HFD3_k127_5764424_11 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000004996 183.0
HFD3_k127_5764424_12 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000001259 129.0
HFD3_k127_5764424_13 proteolysis K21140,K21147 - 2.7.7.80,2.8.1.11,3.13.1.6 0.0000000000000000000000000000001697 131.0
HFD3_k127_5764424_14 - - - - 0.0000000000000000000000000000003144 132.0
HFD3_k127_5764424_15 Putative cyclase - - - 0.0000000000000000000000002481 111.0
HFD3_k127_5764424_16 Transcriptional regulator - - - 0.0000000000000000000000003084 117.0
HFD3_k127_5764424_18 ThiS family K03636 - - 0.0000000000000000000004617 100.0
HFD3_k127_5764424_19 Putative cyclase - - - 0.000000000000000001822 85.0
HFD3_k127_5764424_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 440.0
HFD3_k127_5764424_3 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 433.0
HFD3_k127_5764424_4 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 403.0
HFD3_k127_5764424_5 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 391.0
HFD3_k127_5764424_6 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007491 368.0
HFD3_k127_5764424_7 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001046 256.0
HFD3_k127_5764424_8 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000004501 263.0
HFD3_k127_5764424_9 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000006986 226.0
HFD3_k127_57708_0 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007616 387.0
HFD3_k127_57708_1 aldo-keto reductase (NADP) activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 357.0
HFD3_k127_57708_2 glucose sorbosone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006056 359.0
HFD3_k127_57708_3 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000005662 198.0
HFD3_k127_57708_4 Protein of unknown function (DUF1566) - - - 0.000000000000000000000000000000000000000003633 176.0
HFD3_k127_57708_5 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000000000000008761 143.0
HFD3_k127_57708_6 - - - - 0.00001129 57.0
HFD3_k127_5780644_0 TOBE domain K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 527.0
HFD3_k127_5780644_1 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 486.0
HFD3_k127_5780644_2 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 474.0
HFD3_k127_5780644_3 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 481.0
HFD3_k127_5780644_4 Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004847 430.0
HFD3_k127_5780644_5 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 333.0
HFD3_k127_5780644_6 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 338.0
HFD3_k127_5780644_7 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004981 287.0
HFD3_k127_5780644_8 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000002923 247.0
HFD3_k127_5780644_9 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000000002424 127.0
HFD3_k127_5783252_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1294.0
HFD3_k127_5783252_1 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 545.0
HFD3_k127_5783422_0 Xanthine dehydrogenase K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007695 616.0
HFD3_k127_5783422_1 Methionine synthase vitamin-B12 independent K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000931 554.0
HFD3_k127_5783422_10 Inorganic pyrophosphatase K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000002412 272.0
HFD3_k127_5783422_11 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003385 259.0
HFD3_k127_5783422_12 AsnC family K03719 - - 0.0005687 47.0
HFD3_k127_5783422_2 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 494.0
HFD3_k127_5783422_3 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 339.0
HFD3_k127_5783422_4 carbon monoxide dehydrogenase K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 321.0
HFD3_k127_5783422_5 3-carboxyethylcatechol 2,3-dioxygenase activity K05713 - 1.13.11.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 296.0
HFD3_k127_5783422_6 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 293.0
HFD3_k127_5783422_7 COG4177 ABC-type branched-chain amino acid transport system, permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005231 285.0
HFD3_k127_5783422_8 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001634 273.0
HFD3_k127_5783422_9 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001643 281.0
HFD3_k127_5807015_0 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 355.0
HFD3_k127_5807015_1 F420-dependent oxidoreductase, Rv2161c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 289.0
HFD3_k127_5809911_0 3-isopropylmalate dehydrogenase activity K00030,K00052 - 1.1.1.41,1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 510.0
HFD3_k127_5809911_1 5'-nucleotidase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 494.0
HFD3_k127_5809911_10 nitrous oxide K19341 - - 0.00001506 49.0
HFD3_k127_5809911_2 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008224 374.0
HFD3_k127_5809911_3 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000000000000000000000000000000000000000000000002634 252.0
HFD3_k127_5809911_4 Uncharacterised nucleotidyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000685 219.0
HFD3_k127_5809911_5 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000001686 201.0
HFD3_k127_5809911_6 Domain of unknown function (DUF3597) - - - 0.000000000000000000000000000000000000000000000004044 180.0
HFD3_k127_5809911_7 Protein of unknown function (DUF2868) - - - 0.0000000000000000000000000000000000000002932 173.0
HFD3_k127_5809911_8 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000008179 134.0
HFD3_k127_5809911_9 - - - - 0.00000000000000000006135 105.0
HFD3_k127_5810420_0 monooxygenase - - - 5.02e-214 672.0
HFD3_k127_5810420_1 Bacterial extracellular solute-binding protein K02027,K10236 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 327.0
HFD3_k127_5810420_10 translation initiation inhibitor, yjgF family - - - 0.00000000000000000000000000000000000000000000004054 175.0
HFD3_k127_5810420_11 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway K01845 - 5.4.3.8 0.000000000000000000000000000006986 125.0
HFD3_k127_5810420_12 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000000003896 117.0
HFD3_k127_5810420_13 Aminotransferase class-III - - - 0.00000000003904 68.0
HFD3_k127_5810420_2 Protein of unknown function (DUF1207) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 319.0
HFD3_k127_5810420_3 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749,K18702 - 2.8.3.16,2.8.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009806 302.0
HFD3_k127_5810420_4 Dihydropyrimidinase K01464 - 3.5.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000003295 298.0
HFD3_k127_5810420_5 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000003498 271.0
HFD3_k127_5810420_6 Binding-protein-dependent transport system inner membrane component K02025,K10237,K15771 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.0000000000000000000000000000000000000000000000000000000000000000000000031 267.0
HFD3_k127_5810420_7 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001683 252.0
HFD3_k127_5810420_8 Binding-protein-dependent transport system inner membrane component K02026,K10238 - - 0.00000000000000000000000000000000000000000000000000000000000000001927 245.0
HFD3_k127_5810420_9 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K03366 - 1.1.1.304,1.1.1.76 0.000000000000000000000000000000000000000000000000000000434 202.0
HFD3_k127_5857575_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 623.0
HFD3_k127_5857575_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 492.0
HFD3_k127_5857575_10 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006643 349.0
HFD3_k127_5857575_11 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 336.0
HFD3_k127_5857575_12 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 333.0
HFD3_k127_5857575_13 Sir2 family K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 310.0
HFD3_k127_5857575_14 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001978 283.0
HFD3_k127_5857575_15 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000004012 241.0
HFD3_k127_5857575_16 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000004267 233.0
HFD3_k127_5857575_17 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000007963 242.0
HFD3_k127_5857575_18 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000008399 218.0
HFD3_k127_5857575_19 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000005425 228.0
HFD3_k127_5857575_2 CoA carboxylase activity K01968 - 6.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 472.0
HFD3_k127_5857575_20 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000002618 220.0
HFD3_k127_5857575_21 Protein of unknown function (DUF455) K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000001166 212.0
HFD3_k127_5857575_22 Belongs to the CinA family - - - 0.0000000000000000000000000000000000000000000000000000001044 205.0
HFD3_k127_5857575_23 transport, permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000005105 194.0
HFD3_k127_5857575_24 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000009188 194.0
HFD3_k127_5857575_25 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.00000000000000000000000000000000000000000001531 176.0
HFD3_k127_5857575_26 Ribosomal protein S9/S16 K02996 - - 0.00000000000000000000000000000000000000000009493 171.0
HFD3_k127_5857575_27 DinB superfamily K07552 - - 0.0000000000000000000000000000002301 129.0
HFD3_k127_5857575_28 Catalytic LigB subunit of aromatic ring-opening dioxygenase K04099,K04101 - 1.13.11.57,1.13.11.8 0.00000000000000000000000000003538 136.0
HFD3_k127_5857575_29 Acetyl propionyl-CoA carboxylase alpha subunit K02160 - - 0.00000000000000005617 84.0
HFD3_k127_5857575_3 PFAM Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 474.0
HFD3_k127_5857575_30 Protein of unknown function (DUF455) - - - 0.0000000000009138 81.0
HFD3_k127_5857575_31 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0040007,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.000000000003174 77.0
HFD3_k127_5857575_32 Belongs to the UPF0312 family - - - 0.000000001042 68.0
HFD3_k127_5857575_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 427.0
HFD3_k127_5857575_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000393 424.0
HFD3_k127_5857575_6 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009845 382.0
HFD3_k127_5857575_7 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 368.0
HFD3_k127_5857575_8 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 357.0
HFD3_k127_5857575_9 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 347.0
HFD3_k127_5887686_0 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 378.0
HFD3_k127_5887686_1 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 305.0
HFD3_k127_5905_0 Pyridoxal-phosphate dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 383.0
HFD3_k127_5905_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K04091 - 1.14.14.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005617 347.0
HFD3_k127_5905_2 Creatinase/Prolidase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004037 267.0
HFD3_k127_5905_3 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K00320 - 1.5.98.2 0.00000000000000000000000000000000000000000000000000000001494 212.0
HFD3_k127_5905_4 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000006082 178.0
HFD3_k127_5905_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000004973 132.0
HFD3_k127_5922050_0 Glycosyl transferase, family 2 - - - 6.733e-309 969.0
HFD3_k127_5922050_1 PFAM ABC transporter, transmembrane region K06147,K11085 - - 4.403e-237 753.0
HFD3_k127_5922050_10 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000234 109.0
HFD3_k127_5922050_2 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000512 412.0
HFD3_k127_5922050_3 Phosphopantetheine attachment site - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008181 327.0
HFD3_k127_5922050_4 Oxygenase, catalysing oxidative methylation of damaged DNA K09990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001259 286.0
HFD3_k127_5922050_5 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000001332 223.0
HFD3_k127_5922050_6 PFAM PfkB domain protein - - - 0.00000000000000000000000000000000000000000006147 170.0
HFD3_k127_5922050_7 Metal binding domain of Ada K00567 - 2.1.1.63 0.00000000000000000000000000000000000003041 158.0
HFD3_k127_5922050_8 Acyl-CoA dehydrogenase, C-terminal domain K00249,K11731 - 1.3.8.7 0.0000000000000000000000000000000000001725 144.0
HFD3_k127_5922050_9 Cyclophilin-like K09143 - - 0.000000000000000000000000000000000002927 143.0
HFD3_k127_5924179_0 Pyruvate kinase K00873 GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009995 438.0
HFD3_k127_5924179_1 Carboxyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000003045 214.0
HFD3_k127_5924179_2 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000005919 211.0
HFD3_k127_5924179_3 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000276 130.0
HFD3_k127_5924179_4 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000005559 117.0
HFD3_k127_5924179_5 Domain of unknown function (DUF1992) - - - 0.0000000000000000000000000203 121.0
HFD3_k127_5928427_0 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 8.958e-245 795.0
HFD3_k127_5928427_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 619.0
HFD3_k127_5928427_2 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 308.0
HFD3_k127_5928427_3 Phosphoenolpyruvate phosphomutase K20454 - 4.1.3.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004097 295.0
HFD3_k127_5928427_4 PFAM peptidase M48 Ste24p K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000001598 244.0
HFD3_k127_5928427_5 Histidine kinase K02482,K03557 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000367 198.0
HFD3_k127_5928427_6 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000001601 78.0
HFD3_k127_5928427_7 Tautomerase enzyme - - - 0.0000000004357 69.0
HFD3_k127_5932443_1 Lanthionine synthetase C family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 321.0
HFD3_k127_5932443_2 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000001122 224.0
HFD3_k127_5932443_3 bacterial-type flagellum-dependent cell motility - - - 0.00000000000000000000000000000000000000000000000000000002229 208.0
HFD3_k127_5934321_0 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 473.0
HFD3_k127_5934321_1 (ABC) transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 372.0
HFD3_k127_5934321_2 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 319.0
HFD3_k127_5938814_0 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 444.0
HFD3_k127_5938814_1 COG2513 PEP phosphonomutase and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000479 261.0
HFD3_k127_5945206_0 SMART Tetratricopeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000767 357.0
HFD3_k127_5945206_1 capsule polysaccharide biosynthetic process K13687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 340.0
HFD3_k127_5945206_10 HEAT repeat - - - 0.00000015 64.0
HFD3_k127_5945206_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 322.0
HFD3_k127_5945206_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001763 247.0
HFD3_k127_5945206_5 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000002459 185.0
HFD3_k127_5945206_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000005166 170.0
HFD3_k127_5945206_7 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000002185 108.0
HFD3_k127_5945206_8 Phosphopantetheine attachment site - - - 0.0000000002855 74.0
HFD3_k127_5945206_9 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000001402 65.0
HFD3_k127_5948473_0 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 399.0
HFD3_k127_5948473_1 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 390.0
HFD3_k127_5948473_10 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000258 236.0
HFD3_k127_5948473_11 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000008439 220.0
HFD3_k127_5948473_12 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000001217 220.0
HFD3_k127_5948473_13 PFAM NADP oxidoreductase coenzyme F420-dependent K00020 - 1.1.1.31 0.000000000000000000000000000000000004618 155.0
HFD3_k127_5948473_14 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000006353 128.0
HFD3_k127_5948473_15 COG0457 FOG TPR repeat - - - 0.0000000000000000000000001122 122.0
HFD3_k127_5948473_16 Rieske [2Fe-2S] domain K15762 - - 0.0000000000000000000000326 108.0
HFD3_k127_5948473_17 Ferredoxin - - - 0.0000000000000000001349 97.0
HFD3_k127_5948473_18 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000329 70.0
HFD3_k127_5948473_2 Oxidoreductase FAD-binding domain K15765 - 1.18.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 365.0
HFD3_k127_5948473_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 379.0
HFD3_k127_5948473_4 cysteine-tRNA ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 347.0
HFD3_k127_5948473_5 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005818 332.0
HFD3_k127_5948473_6 Amino-transferase class IV K18482 - 4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 301.0
HFD3_k127_5948473_7 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003952 289.0
HFD3_k127_5948473_8 Alpha/beta hydrolase family K01055 - 3.1.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000002038 269.0
HFD3_k127_5948473_9 exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000005769 267.0
HFD3_k127_5998254_0 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 503.0
HFD3_k127_5998254_1 Penicillin-binding protein 2 K05515 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004734 472.0
HFD3_k127_5998254_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 318.0
HFD3_k127_5998254_3 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001578 277.0
HFD3_k127_5998254_4 Cell shape-determining protein MreC K03570 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0030428,GO:0031224,GO:0031226,GO:0042546,GO:0043621,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944,GO:0071963 - 0.000000000000000000000000000000000000000178 161.0
HFD3_k127_5998254_5 shape-determining protein MreD K03571 - - 0.0000000000001791 83.0
HFD3_k127_599863_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 526.0
HFD3_k127_599863_1 phosphorelay signal transduction system K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 522.0
HFD3_k127_599863_2 Multi-sensor signal transduction histidine kinase K07710 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 527.0
HFD3_k127_599863_3 Histidyl-tRNA synthetase K00765,K01892,K02502 - 2.4.2.17,6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 383.0
HFD3_k127_599863_4 Belongs to the phosphoglycerate mutase family K02226,K22305 - 3.1.3.3,3.1.3.73 0.0000000003584 64.0
HFD3_k127_6004725_0 Aminotransferase class-III K03918,K07250,K20428 - 2.6.1.19,2.6.1.22,2.6.1.33,2.6.1.36 9.778e-198 640.0
HFD3_k127_6004725_1 MMPL family K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004042 480.0
HFD3_k127_6004725_10 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000001801 107.0
HFD3_k127_6004725_2 Copper resistance protein D K07245 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 389.0
HFD3_k127_6004725_3 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 314.0
HFD3_k127_6004725_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003371 275.0
HFD3_k127_6004725_5 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K03802,K05844 - 6.3.2.29,6.3.2.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000626 262.0
HFD3_k127_6004725_6 Belongs to the malate synthase family K01638 - 2.3.3.9 0.000000000000000000000000000000000000000000000000000000000000000000004438 256.0
HFD3_k127_6004725_7 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01560,K07025,K20862 - 3.1.3.102,3.1.3.104,3.8.1.2 0.00000000000000000000000000000000000000000000000000000000001643 213.0
HFD3_k127_6004725_8 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00966,K05305,K16881 - 2.7.1.52,2.7.7.13,5.4.2.8 0.00000000000000000000000000000000000000000000000000000001398 209.0
HFD3_k127_6004725_9 Myo-inositol-1-phosphate synthase, GAPDH domain protein K01858 - 5.5.1.4 0.0000000000000000000000000000000000000000000000000000003325 195.0
HFD3_k127_6005674_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 423.0
HFD3_k127_6005674_1 Sodium/hydrogen exchanger family K03455 - - 0.00000000000000000000000000000000000000000000000000000000000002352 220.0
HFD3_k127_6005798_0 Acetyl-coenzyme A synthetase N-terminus K01908 - 6.2.1.17 1.444e-306 950.0
HFD3_k127_6005798_1 PFAM Sulfatase K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 481.0
HFD3_k127_6005798_10 transport system periplasmic component K21395 - - 0.00000000000000000000000000000000000000000000004336 184.0
HFD3_k127_6005798_11 Cysteine-rich motif following a subset of SET domains K07117 - - 0.00000000000000000000000000000000000000001107 169.0
HFD3_k127_6005798_12 Type II secretory pathway, component ExeA K02450 - - 0.0000000000000000000000005237 120.0
HFD3_k127_6005798_13 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000001323 90.0
HFD3_k127_6005798_14 spore germination - - - 0.000000000005693 78.0
HFD3_k127_6005798_2 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 396.0
HFD3_k127_6005798_3 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 404.0
HFD3_k127_6005798_4 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001376 276.0
HFD3_k127_6005798_5 Fatty acid desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002558 271.0
HFD3_k127_6005798_6 Belongs to the Nudix hydrolase family K03426 - 3.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000002847 262.0
HFD3_k127_6005798_7 mannose-ethanolamine phosphotransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000006799 240.0
HFD3_k127_6005798_8 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000004456 224.0
HFD3_k127_6005798_9 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000000000000000000000001384 177.0
HFD3_k127_6100194_0 Amino-transferase class IV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007534 405.0
HFD3_k127_6100194_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 302.0
HFD3_k127_6100194_2 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006888 279.0
HFD3_k127_6100194_3 peroxiredoxin activity K01607 - 4.1.1.44 0.0000000000000000000000000000000000000000001221 166.0
HFD3_k127_6100194_4 transferase activity, transferring glycosyl groups K20444 - - 0.00000000000000000000000000000000006263 148.0
HFD3_k127_6100194_6 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000005274 58.0
HFD3_k127_611474_0 Thiamine pyrophosphate protein TPP binding domain protein K01652 - 2.2.1.6 2.083e-257 805.0
HFD3_k127_611474_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 2.902e-220 695.0
HFD3_k127_611474_10 Short-chain dehydrogenase reductase (SDR) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 322.0
HFD3_k127_611474_11 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 308.0
HFD3_k127_611474_12 alpha/beta hydrolase fold K01066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 297.0
HFD3_k127_611474_13 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008034 302.0
HFD3_k127_611474_14 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002363 248.0
HFD3_k127_611474_15 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000007976 258.0
HFD3_k127_611474_16 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000002735 210.0
HFD3_k127_611474_17 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000007572 201.0
HFD3_k127_611474_18 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000007127 185.0
HFD3_k127_611474_19 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000009907 186.0
HFD3_k127_611474_2 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 559.0
HFD3_k127_611474_20 MlaD protein K06192 - - 0.0000000000000000000000000000000000000004033 169.0
HFD3_k127_611474_21 pyrroloquinoline quinone binding - - - 0.000000000000000000000000000000000000000436 169.0
HFD3_k127_611474_22 Protein of unknown function, DUF - - - 0.00000000000000000000000000000000000001053 149.0
HFD3_k127_611474_23 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.00000000000000000000000000000000000002411 145.0
HFD3_k127_611474_24 ABC-type transport auxiliary lipoprotein component K09857 - - 0.00000000000000000000000000000000001878 154.0
HFD3_k127_611474_26 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000001509 115.0
HFD3_k127_611474_28 bacterial-type flagellum-dependent cell motility - - - 0.00000000000000000003077 101.0
HFD3_k127_611474_29 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 GO:0000287,GO:0003674,GO:0003824,GO:0004016,GO:0004383,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006171,GO:0006182,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0007186,GO:0007187,GO:0007188,GO:0007189,GO:0008074,GO:0008150,GO:0008152,GO:0008179,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009187,GO:0009190,GO:0009259,GO:0009260,GO:0009975,GO:0009987,GO:0010033,GO:0014070,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019899,GO:0019932,GO:0019933,GO:0019935,GO:0023052,GO:0030145,GO:0030425,GO:0031224,GO:0031226,GO:0031683,GO:0032991,GO:0033993,GO:0034641,GO:0034654,GO:0035556,GO:0035690,GO:0036477,GO:0042221,GO:0042493,GO:0042995,GO:0043005,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044444,GO:0044445,GO:0044459,GO:0044463,GO:0044464,GO:0044877,GO:0045121,GO:0046058,GO:0046068,GO:0046390,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0046982,GO:0046983,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052652,GO:0055086,GO:0061478,GO:0065007,GO:0070887,GO:0071236,GO:0071310,GO:0071396,GO:0071407,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097305,GO:0097306,GO:0097447,GO:0097458,GO:0098589,GO:0098805,GO:0098857,GO:0120025,GO:0120038,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901654,GO:1901655,GO:1901700,GO:1901701,GO:1904321,GO:1904322 4.6.1.1 0.0000000000002506 82.0
HFD3_k127_611474_3 PFAM amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 543.0
HFD3_k127_611474_30 - - - - 0.00000000000131 75.0
HFD3_k127_611474_31 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000001049 63.0
HFD3_k127_611474_32 Periplasmic copper-binding protein (NosD) - - - 0.000008224 59.0
HFD3_k127_611474_33 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - 0.00002435 51.0
HFD3_k127_611474_4 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 434.0
HFD3_k127_611474_5 phosphoglycerate mutase activity K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007489 403.0
HFD3_k127_611474_6 Amidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 429.0
HFD3_k127_611474_7 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 394.0
HFD3_k127_611474_8 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008663 415.0
HFD3_k127_611474_9 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 373.0
HFD3_k127_6116535_0 PglZ domain - - - 3.475e-198 638.0
HFD3_k127_6116535_1 ABC transporter transmembrane region K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 514.0
HFD3_k127_6116535_2 Glycosyl transferase, family 9 K02843 - - 0.00000000000000006444 85.0
HFD3_k127_6142237_0 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007302 410.0
HFD3_k127_6142237_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007871 402.0
HFD3_k127_6142237_2 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000003179 231.0
HFD3_k127_6142237_3 Protein of unknown function (DUF3047) - - - 0.00000000000000000000000000000000000000000000000000000000001905 223.0
HFD3_k127_6161650_0 Methionine synthase K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001042 297.0
HFD3_k127_6161650_1 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000001047 211.0
HFD3_k127_6161650_2 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051604,GO:0051716,GO:0070417,GO:0071704,GO:0097159,GO:0097367,GO:0097428,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1990230,GO:1990234 - 0.0000000000000000000000000000005156 134.0
HFD3_k127_6161650_3 - - - - 0.0000000000000000000000825 112.0
HFD3_k127_6161650_5 - - - - 0.000001734 60.0
HFD3_k127_6224901_0 xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 2.191e-263 834.0
HFD3_k127_6224901_1 Nitrile hydratase beta subunit - - - 0.00000000000000000000000000000000000000000000000000000000001324 209.0
HFD3_k127_6224901_2 [2Fe-2S] binding domain - - - 0.000000000000000000000000000000000000000000000000000001833 205.0
HFD3_k127_6224901_3 NHase catalyzes the hydration of various nitrile compounds to the corresponding amides K20807 - 4.2.1.84 0.0000000000000000000000000000000000000000000000009461 175.0
HFD3_k127_6224901_4 CO dehydrogenase flavoprotein domain protein K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000009207 171.0
HFD3_k127_6224901_5 IMP dehydrogenase activity K04767 - - 0.000000000000000000000003315 109.0
HFD3_k127_6225463_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 6.124e-246 768.0
HFD3_k127_6225463_1 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 598.0
HFD3_k127_6225463_10 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007047 256.0
HFD3_k127_6225463_11 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000001642 250.0
HFD3_k127_6225463_12 ATP-binding region, ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000197 237.0
HFD3_k127_6225463_13 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000007766 228.0
HFD3_k127_6225463_14 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000001699 210.0
HFD3_k127_6225463_15 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594,K07052 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000004545 211.0
HFD3_k127_6225463_16 PFAM glutamine amidotransferase class-I K07010 - - 0.000000000000000000000000000000000000000000000000005452 207.0
HFD3_k127_6225463_17 AAA ATPase domain K05847 - - 0.00000000000000000000000000000000000001068 152.0
HFD3_k127_6225463_18 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.00000000000000000000000000006543 134.0
HFD3_k127_6225463_19 VIT family - - - 0.000000000000004128 85.0
HFD3_k127_6225463_2 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 548.0
HFD3_k127_6225463_3 Radical SAM superfamily K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006073 462.0
HFD3_k127_6225463_4 overlaps another CDS with the same product name - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005206 389.0
HFD3_k127_6225463_5 PFAM acyl-CoA dehydrogenase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000954 349.0
HFD3_k127_6225463_6 TIGRFAM amidase, hydantoinase carbamoylase K06016 - 3.5.1.6,3.5.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008238 340.0
HFD3_k127_6225463_7 Ethanolamine utilization protein EutJ K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006326 338.0
HFD3_k127_6225463_8 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007842 309.0
HFD3_k127_6225463_9 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007185 291.0
HFD3_k127_6237424_0 FAD dependent oxidoreductase - - - 2.372e-200 633.0
HFD3_k127_6237424_1 N-terminal domain of (some) glycogen debranching enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007201 602.0
HFD3_k127_6237424_10 - - - - 0.0000000000000007673 84.0
HFD3_k127_6237424_11 - - - - 0.00000000005694 68.0
HFD3_k127_6237424_12 - - - - 0.0000005852 60.0
HFD3_k127_6237424_2 Polysaccharide pyruvyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004577 467.0
HFD3_k127_6237424_3 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005969 406.0
HFD3_k127_6237424_4 metallophosphoesterase K07096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 331.0
HFD3_k127_6237424_5 Nucleotidyl transferase of unknown function (DUF2204) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005181 313.0
HFD3_k127_6237424_6 Pfam:UPF0118 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 304.0
HFD3_k127_6237424_7 Ribonuclease, BN K07058 - - 0.00000000000000000000000000000000000000000000000000000000005512 217.0
HFD3_k127_6237424_8 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000006635 149.0
HFD3_k127_6237424_9 - - - - 0.0000000000000000003247 98.0
HFD3_k127_6239706_0 DegT/DnrJ/EryC1/StrS aminotransferase family K04127 - 5.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007455 490.0
HFD3_k127_6239706_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 437.0
HFD3_k127_6239706_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 327.0
HFD3_k127_6239706_3 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000005998 220.0
HFD3_k127_6239706_4 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.000000000000000000000000000000000000000001053 177.0
HFD3_k127_6239706_5 inositol 2-dehydrogenase activity - - - 0.000000000000000000000019 103.0
HFD3_k127_6254210_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000473 511.0
HFD3_k127_6254210_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 418.0
HFD3_k127_6254210_2 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 295.0
HFD3_k127_6254210_3 P-aminobenzoate N-oxygenase AurF - - - 0.00000000000000000000000000000000000000000000000001747 192.0
HFD3_k127_6254210_4 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000004874 139.0
HFD3_k127_6254210_5 PFAM Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.0000000000000000000000184 114.0
HFD3_k127_6254210_6 Domain of unknown function (DUF4149) - - - 0.0000001244 64.0
HFD3_k127_6254210_7 Tetratricopeptide repeat - - - 0.000003525 59.0
HFD3_k127_6293354_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006457,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042802,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061077,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680 - 0.0 1062.0
HFD3_k127_6293354_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006203 385.0
HFD3_k127_6293354_2 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 385.0
HFD3_k127_6293354_3 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 316.0
HFD3_k127_6293354_4 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001078 270.0
HFD3_k127_6293354_5 ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000005514 265.0
HFD3_k127_6293354_6 (Rhomboid) family - - - 0.000000000000000000000000000000000000000000000000000000000000007869 225.0
HFD3_k127_6293354_7 PFAM binding-protein-dependent transport systems inner membrane component K02042 - - 0.000000000000000000000000000000000000000000000000000000000006152 228.0
HFD3_k127_6293354_8 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000004435 216.0
HFD3_k127_6293354_9 PFAM Histidine triad (HIT) protein K02503 - - 0.00000000000000000000000000000001172 131.0
HFD3_k127_6304107_0 ABC transporter transmembrane region - - - 3.194e-317 998.0
HFD3_k127_6304107_1 FMN-dependent dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 460.0
HFD3_k127_6304107_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 369.0
HFD3_k127_6308141_0 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 604.0
HFD3_k127_6308141_1 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 492.0
HFD3_k127_6308141_2 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005324 347.0
HFD3_k127_6308141_3 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005466 280.0
HFD3_k127_6308141_4 short-chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004647 261.0
HFD3_k127_6310964_0 - - - - 0.00000000000000000000000000000000000000000000000007759 187.0
HFD3_k127_6310964_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000001666 138.0
HFD3_k127_6310964_2 Peptidoglycan binding domain - - - 0.000002974 56.0
HFD3_k127_6315962_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K04090 - 1.2.7.8 0.0 1298.0
HFD3_k127_6315962_1 FtsX-like permease family K02004 - - 8.461e-206 677.0
HFD3_k127_6315962_10 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 370.0
HFD3_k127_6315962_11 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 378.0
HFD3_k127_6315962_12 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 339.0
HFD3_k127_6315962_13 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004792 306.0
HFD3_k127_6315962_14 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006025 335.0
HFD3_k127_6315962_15 Binding-protein-dependent transport system inner membrane component K02033,K15585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007419 298.0
HFD3_k127_6315962_16 lipoprotein transporter activity K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004017 273.0
HFD3_k127_6315962_17 permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009723 268.0
HFD3_k127_6315962_18 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000004891 261.0
HFD3_k127_6315962_19 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000001424 219.0
HFD3_k127_6315962_2 UDP-N-acetylmuramate-L-alanine ligase activity K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 552.0
HFD3_k127_6315962_20 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000007009 208.0
HFD3_k127_6315962_21 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.00000000000000000000000000000000000000008168 172.0
HFD3_k127_6315962_22 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.000000000000000000000000000001973 125.0
HFD3_k127_6315962_23 Regulatory protein, FmdB family - - - 0.00000000000000000006294 94.0
HFD3_k127_6315962_24 PFAM ROSMUCR transcriptional regulator - - - 0.0000000000856 69.0
HFD3_k127_6315962_25 pilus assembly protein PilW K02672 - - 0.0000000001341 69.0
HFD3_k127_6315962_26 POTRA domain, FtsQ-type K03589 - - 0.000000000341 74.0
HFD3_k127_6315962_27 Cell division protein FtsL - - - 0.0002569 51.0
HFD3_k127_6315962_3 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 528.0
HFD3_k127_6315962_4 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 506.0
HFD3_k127_6315962_5 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009331 464.0
HFD3_k127_6315962_6 to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 458.0
HFD3_k127_6315962_7 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 441.0
HFD3_k127_6315962_8 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004264 427.0
HFD3_k127_6315962_9 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 389.0
HFD3_k127_6320450_0 AMP-binding enzyme K15868 - 6.2.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 586.0
HFD3_k127_6320450_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 565.0
HFD3_k127_6320450_10 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003478 299.0
HFD3_k127_6320450_11 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007098 284.0
HFD3_k127_6320450_12 PFAM extracellular solute-binding protein family 1 K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001309 281.0
HFD3_k127_6320450_13 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004549 263.0
HFD3_k127_6320450_14 Pfam:Pyridox_oxidase K07006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000149 254.0
HFD3_k127_6320450_15 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000001212 245.0
HFD3_k127_6320450_16 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000004379 226.0
HFD3_k127_6320450_17 3-demethylubiquinone-9 3-methyltransferase K04750 - - 0.000000000000000000000000000000000000000000000000000008342 202.0
HFD3_k127_6320450_18 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000001137 215.0
HFD3_k127_6320450_19 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000009711 195.0
HFD3_k127_6320450_2 Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005964 548.0
HFD3_k127_6320450_20 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000002895 182.0
HFD3_k127_6320450_22 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000002213 141.0
HFD3_k127_6320450_23 membrane K08983 - - 0.0000000000000000000000000000002995 132.0
HFD3_k127_6320450_24 Glyoxalase-like domain K08234 - - 0.0000000000000000000000000000005555 129.0
HFD3_k127_6320450_25 Thioredoxin - - - 0.00000000000000000000001922 114.0
HFD3_k127_6320450_26 Polysaccharide biosynthesis protein - - - 0.00000000000000000003578 103.0
HFD3_k127_6320450_27 - - - - 0.000000000006789 70.0
HFD3_k127_6320450_28 protein conserved in bacteria K21470 - - 0.0001643 45.0
HFD3_k127_6320450_3 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 507.0
HFD3_k127_6320450_4 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007525 371.0
HFD3_k127_6320450_5 Polyprenyl synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 344.0
HFD3_k127_6320450_6 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 310.0
HFD3_k127_6320450_7 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004065 314.0
HFD3_k127_6320450_8 Cysteine desulfurase K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 299.0
HFD3_k127_6320450_9 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 304.0
HFD3_k127_6343923_0 Malic enzyme K00029 - 1.1.1.40 0.0 1093.0
HFD3_k127_6343923_1 EamA-like transporter family - - - 0.0000000000000000000009623 99.0
HFD3_k127_6378121_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 0.0 1098.0
HFD3_k127_6378121_1 benzoyl-CoA reductase K04113 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000902 310.0
HFD3_k127_6378121_2 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000001558 285.0
HFD3_k127_6378121_3 BadF/BadG/BcrA/BcrD ATPase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001137 272.0
HFD3_k127_6378121_4 4Fe-4S binding domain K18362 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007447 261.0
HFD3_k127_6378121_5 dmso reductase anchor subunit - - - 0.000000000000000000000000000004013 131.0
HFD3_k127_6378121_6 Bacterial regulatory proteins, tetR family K09017 - - 0.0000000000000000004311 96.0
HFD3_k127_6386118_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 7.027e-250 788.0
HFD3_k127_6386118_1 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 492.0
HFD3_k127_6386118_10 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.000000000000000000000000000000001584 138.0
HFD3_k127_6386118_11 metallopeptidase activity - - - 0.00000000000008556 84.0
HFD3_k127_6386118_2 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 428.0
HFD3_k127_6386118_3 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004741 432.0
HFD3_k127_6386118_4 Binding-protein-dependent transport system inner membrane component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005285 362.0
HFD3_k127_6386118_5 Hydrogenase expression formation protein (HypE) K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 323.0
HFD3_k127_6386118_6 COG3842 ABC-type spermidine putrescine transport systems, ATPase components K02010,K02017,K15497 - 3.6.3.29,3.6.3.30,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 317.0
HFD3_k127_6386118_7 Formiminotransferase domain, N-terminal subdomain K00603 - 2.1.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000529 265.0
HFD3_k127_6386118_8 Rhs element vgr protein - - - 0.000000000000000000000000000000000000000000000000001854 194.0
HFD3_k127_6386118_9 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000003116 154.0
HFD3_k127_6391213_0 Belongs to the heme-copper respiratory oxidase family K02274 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 537.0
HFD3_k127_6391213_1 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 339.0
HFD3_k127_6391213_2 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000000000000000000000000000000002837 226.0
HFD3_k127_6391213_3 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000005165 207.0
HFD3_k127_6391213_4 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000004026 206.0
HFD3_k127_6421115_0 Major facilitator superfamily K08167 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 598.0
HFD3_k127_6421115_1 Arginase family K01476 - 3.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 387.0
HFD3_k127_6421115_2 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 324.0
HFD3_k127_6421115_3 sigma factor activity K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004557 327.0
HFD3_k127_6421115_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008677 303.0
HFD3_k127_6421115_5 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000006614 190.0
HFD3_k127_6421115_6 epimerase - - - 0.000000000000000000000246 103.0
HFD3_k127_6421115_7 Plasmid pRiA4b ORF-3-like protein - - - 0.000000000000003438 78.0
HFD3_k127_6421115_8 YCII-related domain - - - 0.000005904 56.0
HFD3_k127_6449202_0 Proto-chlorophyllide reductase 57 kD subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003084 252.0
HFD3_k127_6449202_1 protein tyrosine kinase activity K03593 - - 0.0000000000000000000000000000000000000000201 165.0
HFD3_k127_6449202_3 deoxyhypusine monooxygenase activity - - - 0.000000000002367 70.0
HFD3_k127_6449202_4 deoxyhypusine monooxygenase activity - - - 0.000128 53.0
HFD3_k127_6452721_0 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007877 592.0
HFD3_k127_6452721_1 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000000000000000000000000000000000007842 180.0
HFD3_k127_6452721_2 Type II secretion system (T2SS), protein E, N-terminal domain K02652 - - 0.0000000009741 60.0
HFD3_k127_6460136_0 Hydantoinase B/oxoprolinase - - - 1.1e-212 674.0
HFD3_k127_6460136_1 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 1.474e-210 679.0
HFD3_k127_6460136_10 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000579 173.0
HFD3_k127_6460136_11 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000008246 174.0
HFD3_k127_6460136_12 Domain of unknown function (DUF1989) K09967 - - 0.000000000000002312 76.0
HFD3_k127_6460136_13 Beta-lactamase - - - 0.0000006146 59.0
HFD3_k127_6460136_2 Hydantoinase/oxoprolinase K01469,K01473 - 3.5.2.14,3.5.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007956 549.0
HFD3_k127_6460136_3 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 457.0
HFD3_k127_6460136_4 Belongs to the amidase family K01426,K19795 - 3.5.1.4,3.5.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 437.0
HFD3_k127_6460136_5 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 342.0
HFD3_k127_6460136_6 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K17228 - 1.14.14.35 0.00000000000000000000000000000000000000000000000000000000000000000009686 241.0
HFD3_k127_6460136_7 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000008724 237.0
HFD3_k127_6460136_8 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs K00087,K03519 - 1.17.1.4,1.2.5.3 0.0000000000000000000000000000000000000000000000003326 192.0
HFD3_k127_6460136_9 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000001646 184.0
HFD3_k127_6471957_0 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 8.309e-283 884.0
HFD3_k127_6471957_1 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 2.82e-218 687.0
HFD3_k127_6471957_10 His Kinase A (phosphoacceptor) domain K02484,K07636,K07768 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007202 503.0
HFD3_k127_6471957_11 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003697 460.0
HFD3_k127_6471957_12 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 427.0
HFD3_k127_6471957_13 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 409.0
HFD3_k127_6471957_14 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005179 405.0
HFD3_k127_6471957_15 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 393.0
HFD3_k127_6471957_16 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009648 402.0
HFD3_k127_6471957_17 DegT/DnrJ/EryC1/StrS aminotransferase family K12452 - 1.17.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 398.0
HFD3_k127_6471957_18 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 381.0
HFD3_k127_6471957_19 TIGRFAM ABC transporter, urea, permease protein, UrtC K01998,K11961 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 372.0
HFD3_k127_6471957_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 1.187e-212 680.0
HFD3_k127_6471957_20 carbamoyl transferase, NodU family K00612,K16035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 384.0
HFD3_k127_6471957_21 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K09461 - 1.14.13.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 375.0
HFD3_k127_6471957_22 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 367.0
HFD3_k127_6471957_23 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 331.0
HFD3_k127_6471957_24 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 317.0
HFD3_k127_6471957_25 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 322.0
HFD3_k127_6471957_26 TIGRFAM ABC transporter, urea, ATP-binding protein, UrtD K11962 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000569 304.0
HFD3_k127_6471957_27 Acetyl-CoA hydrolase/transferase N-terminal domain K18122 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000777 318.0
HFD3_k127_6471957_28 PFAM glycoside hydrolase, family 3 domain protein K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 306.0
HFD3_k127_6471957_29 Two component transcriptional regulator, winged helix family K07658,K07668 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002065 274.0
HFD3_k127_6471957_3 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 1.226e-207 665.0
HFD3_k127_6471957_30 deaminated base DNA N-glycosylase activity K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003931 289.0
HFD3_k127_6471957_31 Inosine-uridine preferring nucleoside hydrolase K01239,K01250 - 3.2.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001468 277.0
HFD3_k127_6471957_32 Urea ABC transporter ATP-binding protein K11963 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002454 259.0
HFD3_k127_6471957_33 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000459 268.0
HFD3_k127_6471957_34 photosystem I assembly BtpA K06971 - - 0.000000000000000000000000000000000000000000000000000000000000000000001733 244.0
HFD3_k127_6471957_35 Asparaginase K13051 - 3.4.19.5 0.000000000000000000000000000000000000000000000000000000000000000000004905 248.0
HFD3_k127_6471957_36 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000003159 239.0
HFD3_k127_6471957_37 Enoyl-(Acyl carrier protein) reductase K00019 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000003834 225.0
HFD3_k127_6471957_38 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000349 228.0
HFD3_k127_6471957_39 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000005225 222.0
HFD3_k127_6471957_4 Ammonium Transporter Family K03320 - - 1.136e-198 630.0
HFD3_k127_6471957_40 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000000000009883 209.0
HFD3_k127_6471957_41 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000002942 220.0
HFD3_k127_6471957_42 PFAM NAD dependent epimerase dehydratase family K01710,K01784 - 4.2.1.46,5.1.3.2 0.000000000000000000000000000000000000000000000000007417 192.0
HFD3_k127_6471957_43 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000001834 176.0
HFD3_k127_6471957_44 Peptidase M16 K07263 - - 0.00000000000000000000000000000000000000000000003704 188.0
HFD3_k127_6471957_45 PFAM Urease beta subunit K01429,K14048 - 3.5.1.5 0.000000000000000000000000000000000000000002495 158.0
HFD3_k127_6471957_46 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000007289 157.0
HFD3_k127_6471957_47 ATP-dependent protease La (LON) substrate-binding domain K01338,K07157 - 3.4.21.53 0.000000000000000000000000000000000000003346 154.0
HFD3_k127_6471957_48 Glycosyl transferase 4-like - - - 0.00000000000000000000000000000000000001313 159.0
HFD3_k127_6471957_49 ANTAR K07183,K22010 - - 0.00000000000000000000000000000000000002146 152.0
HFD3_k127_6471957_5 NAD synthase K01916 - 6.3.1.5 5.294e-197 629.0
HFD3_k127_6471957_50 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.00000000000000000000000000000000000984 151.0
HFD3_k127_6471957_51 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.000000000000000000000000000000001815 139.0
HFD3_k127_6471957_52 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.00000000000000000000000000000000705 139.0
HFD3_k127_6471957_53 regulation of translation K03530 - - 0.000000000000000000000000000001062 127.0
HFD3_k127_6471957_54 PFAM pyridoxamine 5'-phosphate oxidase-related - - - 0.00000000000000000000000000002085 124.0
HFD3_k127_6471957_55 translation initiation inhibitor, yjgF family - - - 0.0000000000000000000000000004979 120.0
HFD3_k127_6471957_56 Belongs to the urease gamma subunit family K01430 - 3.5.1.5 0.000000000000000000000000004803 110.0
HFD3_k127_6471957_57 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000008079 87.0
HFD3_k127_6471957_58 redox protein regulator of disulfide bond formation K07397 - - 0.00000000000005675 74.0
HFD3_k127_6471957_59 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000009635 80.0
HFD3_k127_6471957_6 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003277 610.0
HFD3_k127_6471957_60 Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co- degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation K02485,K07315 GO:0000988,GO:0000989,GO:0003674,GO:0008150,GO:0009889,GO:0009893,GO:0010556,GO:0010604,GO:0016989,GO:0019219,GO:0019222,GO:0030162,GO:0031323,GO:0031325,GO:0031326,GO:0031647,GO:0031648,GO:0032268,GO:0032270,GO:0045862,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0140110,GO:1903506,GO:2001141 3.1.3.3 0.0000000000188 70.0
HFD3_k127_6471957_61 Two component, sigma54 specific, transcriptional regulator, Fis family K07712,K07714 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.00000000004596 69.0
HFD3_k127_6471957_62 Belongs to the urease gamma subunit family K01430 - 3.5.1.5 0.00000000009996 62.0
HFD3_k127_6471957_63 Lrp/AsnC ligand binding domain - - - 0.000000004164 65.0
HFD3_k127_6471957_64 OsmC-like protein K06889,K07397 - - 0.00000001718 57.0
HFD3_k127_6471957_65 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly K03187 - - 0.00000003945 67.0
HFD3_k127_6471957_67 Contains selenocysteine K07401 - - 0.0000008514 52.0
HFD3_k127_6471957_68 Threonine dehydratase K01754 - 4.3.1.19 0.000001619 54.0
HFD3_k127_6471957_69 Acetyltransferase (GNAT) domain - - - 0.0006407 49.0
HFD3_k127_6471957_7 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 526.0
HFD3_k127_6471957_8 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006502 530.0
HFD3_k127_6471957_9 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K06147,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005529 513.0
HFD3_k127_6484090_0 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 579.0
HFD3_k127_6484090_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 533.0
HFD3_k127_6484090_10 Rubredoxin-like zinc ribbon domain (DUF35_N) - - - 0.0000007387 62.0
HFD3_k127_6484090_11 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.0000008507 59.0
HFD3_k127_6484090_2 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 452.0
HFD3_k127_6484090_3 COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase K02031,K02032,K13892 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005638 459.0
HFD3_k127_6484090_4 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008137 427.0
HFD3_k127_6484090_5 Binding-protein-dependent transport system inner membrane component K02033,K15585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 421.0
HFD3_k127_6484090_6 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 382.0
HFD3_k127_6484090_7 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005095 296.0
HFD3_k127_6484090_8 NADH pyrophosphatase zinc ribbon domain K03426 - 3.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000003562 285.0
HFD3_k127_6484090_9 ferredoxin K05524 - - 0.000000000000000000000000000000000005563 139.0
HFD3_k127_6506717_0 PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic K01886 - 6.1.1.18 6.146e-278 863.0
HFD3_k127_6514532_0 Maltogenic Amylase, C-terminal domain K05343 - 3.2.1.1,5.4.99.16 2.315e-283 878.0
HFD3_k127_6514532_1 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 2.212e-230 727.0
HFD3_k127_6514532_10 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000311 186.0
HFD3_k127_6514532_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.0000000000000000000000000000000000000129 149.0
HFD3_k127_6514532_12 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000006484 107.0
HFD3_k127_6514532_13 Thioredoxin - - - 0.0000000000000000000001346 105.0
HFD3_k127_6514532_14 PFAM DinB family protein - - - 0.0000000000000000001645 99.0
HFD3_k127_6514532_2 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 2.975e-215 683.0
HFD3_k127_6514532_3 PFAM amidohydrolase K07045 - - 2e-206 647.0
HFD3_k127_6514532_4 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 514.0
HFD3_k127_6514532_5 acyl-CoA transferases carnitine dehydratase K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 426.0
HFD3_k127_6514532_6 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000975 377.0
HFD3_k127_6514532_7 Phosphotransferase enzyme family K00700,K05343,K16146 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016310,GO:0034637,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046835,GO:0071704,GO:0071944,GO:1901576 2.4.1.18,2.7.1.175,3.2.1.1,5.4.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 311.0
HFD3_k127_6514532_8 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000000005216 231.0
HFD3_k127_6514532_9 Conserved protein of dim6 ntab family - - - 0.000000000000000000000000000000000000000000000000009392 201.0
HFD3_k127_6519129_0 Adenylate and Guanylate cyclase catalytic domain - - - 0.0 1079.0
HFD3_k127_6519129_1 Major Facilitator Superfamily - - - 1.761e-199 629.0
HFD3_k127_6519129_10 2-methylcitrate dehydratase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 314.0
HFD3_k127_6519129_11 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005324 265.0
HFD3_k127_6519129_12 TIM-barrel fold metal-dependent hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001866 271.0
HFD3_k127_6519129_13 CYTH - - - 0.0000000000000000000000000000000000000000000000000000000000000000001707 249.0
HFD3_k127_6519129_14 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000002544 236.0
HFD3_k127_6519129_15 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000005783 231.0
HFD3_k127_6519129_16 Acetohydroxy acid isomeroreductase, NADPH-binding domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000821 225.0
HFD3_k127_6519129_17 pfam abc K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000001761 222.0
HFD3_k127_6519129_18 - K00712 - 2.4.1.52 0.0000000000000000000000000000000000000000000000000000001725 216.0
HFD3_k127_6519129_19 PFAM ABC-2 type transporter K09694 - - 0.0000000000000000000000000000000000009014 158.0
HFD3_k127_6519129_2 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01577,K01652,K03852 - 2.2.1.6,2.3.3.15,4.1.1.8 1.992e-199 638.0
HFD3_k127_6519129_20 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000297 147.0
HFD3_k127_6519129_22 PFAM glycosyl transferase family 39 - - - 0.000000000000000000000000000002862 137.0
HFD3_k127_6519129_23 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000001968 130.0
HFD3_k127_6519129_24 Belongs to the NUDIX hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000004131 121.0
HFD3_k127_6519129_25 PFAM histidine triad (HIT) protein - - - 0.00000000000000000000002192 116.0
HFD3_k127_6519129_26 - - - - 0.000000000000000000000182 109.0
HFD3_k127_6519129_27 rRNA (guanine-N2-)-methyltransferase activity - - - 0.00000000000000000001563 100.0
HFD3_k127_6519129_28 protein conserved in bacteria K09984 - - 0.000000000000000004003 87.0
HFD3_k127_6519129_29 TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.000000000000000009947 88.0
HFD3_k127_6519129_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 471.0
HFD3_k127_6519129_30 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000002035 70.0
HFD3_k127_6519129_31 Haem-degrading - - - 0.0000001392 59.0
HFD3_k127_6519129_32 Endoribonuclease L-PSP - - - 0.0000004251 58.0
HFD3_k127_6519129_4 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009457 452.0
HFD3_k127_6519129_5 D-isomer specific 2-hydroxyacid dehydrogenase K00018 - 1.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007428 428.0
HFD3_k127_6519129_6 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 351.0
HFD3_k127_6519129_7 PFAM RNA binding S1 domain protein K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 356.0
HFD3_k127_6519129_8 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 306.0
HFD3_k127_6519129_9 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 295.0
HFD3_k127_6528400_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 8.2e-260 824.0
HFD3_k127_6528400_1 Belongs to the CinA family - - - 1.847e-198 625.0
HFD3_k127_6528400_10 short-chain K00034,K00038,K00046 - 1.1.1.47,1.1.1.53,1.1.1.69 0.00000000000000000000000000000000000000000000000000000007082 205.0
HFD3_k127_6528400_11 Thiopurine S-methyltransferase (TPMT) - - - 0.0000000000000000000000000000000000000000000000000005895 191.0
HFD3_k127_6528400_12 ROK family - - - 0.00000000000000000000000000000001476 134.0
HFD3_k127_6528400_2 ABC-type sugar transport system, periplasmic component K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 580.0
HFD3_k127_6528400_3 Rieske (2Fe-2S) domain-containing protein K15060 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007227 571.0
HFD3_k127_6528400_4 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain K03520,K11177 - 1.17.1.4,1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007188 533.0
HFD3_k127_6528400_5 III protein, CoA-transferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 500.0
HFD3_k127_6528400_6 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 418.0
HFD3_k127_6528400_7 Binding-protein-dependent transport system inner membrane component K02025,K10237 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000589 393.0
HFD3_k127_6528400_8 Histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 379.0
HFD3_k127_6528400_9 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749,K18702 - 2.8.3.16,2.8.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008855 336.0
HFD3_k127_6538090_0 PFAM aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 0.0 1011.0
HFD3_k127_6538090_1 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 3.563e-194 620.0
HFD3_k127_6538090_10 Short-chain dehydrogenase reductase (SDR) - - - 0.00000000000000000000000000000000000000000000000000000000000000000003427 241.0
HFD3_k127_6538090_11 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000002458 210.0
HFD3_k127_6538090_12 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000001504 206.0
HFD3_k127_6538090_13 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000001229 195.0
HFD3_k127_6538090_14 intermembrane phospholipid transfer K07323 - - 0.0000000000000000000000000000000000000000000000007458 184.0
HFD3_k127_6538090_15 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000001825 179.0
HFD3_k127_6538090_16 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000009587 175.0
HFD3_k127_6538090_17 PFAM pyridoxamine 5'-phosphate oxidase-related - - - 0.0000000000000000000000000000000008621 136.0
HFD3_k127_6538090_18 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000000000000000000000003333 134.0
HFD3_k127_6538090_19 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000002462 128.0
HFD3_k127_6538090_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004523 497.0
HFD3_k127_6538090_20 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000000000001753 99.0
HFD3_k127_6538090_21 cyclopropane-fatty-acyl-phospholipid synthase K00574,K03466 - 2.1.1.79 0.0000000000000001123 87.0
HFD3_k127_6538090_22 ARD/ARD' family - - - 0.000000008821 64.0
HFD3_k127_6538090_23 PFAM plasmid - - - 0.00000002547 60.0
HFD3_k127_6538090_24 Acyl dehydratase - - - 0.00000004586 59.0
HFD3_k127_6538090_25 Putative addiction module component - - - 0.000005563 50.0
HFD3_k127_6538090_3 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 442.0
HFD3_k127_6538090_4 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 441.0
HFD3_k127_6538090_5 PFAM Peptidase M11 gametolysin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 375.0
HFD3_k127_6538090_6 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005943 337.0
HFD3_k127_6538090_7 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006358 337.0
HFD3_k127_6538090_8 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 295.0
HFD3_k127_6538090_9 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 291.0
HFD3_k127_6541091_0 ABC-type branched-chain amino acid transport K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002097 266.0
HFD3_k127_6541091_1 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006494 265.0
HFD3_k127_6541091_2 alpha/beta hydrolase fold - - - 0.000000000000000000000000000007995 129.0
HFD3_k127_6541091_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000001263 108.0
HFD3_k127_6561483_0 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 586.0
HFD3_k127_6561483_1 Protoporphyrinogen oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 567.0
HFD3_k127_6561483_10 Glycosyltransferase K21001 - - 0.000000000000000000003135 108.0
HFD3_k127_6561483_12 polysaccharide biosynthetic process - - - 0.0000000000004391 83.0
HFD3_k127_6561483_13 AntiSigma factor - - - 0.000005731 58.0
HFD3_k127_6561483_14 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00001258 58.0
HFD3_k127_6561483_15 Flavin containing amine oxidoreductase - - - 0.00004279 51.0
HFD3_k127_6561483_2 Domain of unknown function (DUF4139) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 458.0
HFD3_k127_6561483_3 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006849 449.0
HFD3_k127_6561483_4 Domain of unknown function (DUF3482) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 363.0
HFD3_k127_6561483_5 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 324.0
HFD3_k127_6561483_6 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001031 251.0
HFD3_k127_6561483_7 phosphorelay signal transduction system K11443 - - 0.000000000000000000000000000000001313 132.0
HFD3_k127_6561483_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000001244 134.0
HFD3_k127_6561483_9 Glycosyltransferase like family 2 - - - 0.000000000000000000000000002439 123.0
HFD3_k127_6563919_0 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 499.0
HFD3_k127_6563919_1 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 490.0
HFD3_k127_6563919_2 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000002649 219.0
HFD3_k127_6563919_3 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000001109 188.0
HFD3_k127_6563919_4 Cupin 2, conserved barrel domain protein - - - 0.000000000000000367 91.0
HFD3_k127_6563919_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K05606 - 5.1.99.1 0.0000718 50.0
HFD3_k127_6563919_6 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0003087 50.0
HFD3_k127_6567554_0 UvrD/REP helicase N-terminal domain K03657,K07465 - 3.6.4.12 5.441e-305 965.0
HFD3_k127_6567554_1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 427.0
HFD3_k127_6567554_2 Alpha/beta hydrolase family K01055 - 3.1.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 394.0
HFD3_k127_6567554_3 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007699 374.0
HFD3_k127_6567554_4 Amidase K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 385.0
HFD3_k127_6567554_5 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008927 271.0
HFD3_k127_6567554_6 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000145 281.0
HFD3_k127_6567554_7 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000001549 209.0
HFD3_k127_6567554_8 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.00000000000002505 78.0
HFD3_k127_6567554_9 Sugar (and other) transporter - - - 0.0000004755 62.0
HFD3_k127_6585700_0 Amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 527.0
HFD3_k127_6585700_1 AMP-binding enzyme C-terminal domain K04116,K12507 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009224 515.0
HFD3_k127_6585700_2 Acyl-CoA dehydrogenase, N-terminal domain K04117 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 439.0
HFD3_k127_6585700_3 Belongs to the enoyl-CoA hydratase isomerase family. MenB subfamily K01661 - 4.1.3.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006498 370.0
HFD3_k127_6585700_4 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 370.0
HFD3_k127_6585700_5 KR domain K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 361.0
HFD3_k127_6585700_6 PFAM Alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 302.0
HFD3_k127_6585700_7 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.0000000000000000000000000000000000000000000000000000000006562 224.0
HFD3_k127_6585700_8 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000007547 199.0
HFD3_k127_6612381_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 415.0
HFD3_k127_6612381_1 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 302.0
HFD3_k127_6612381_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 304.0
HFD3_k127_6612381_3 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000559 263.0
HFD3_k127_6612381_4 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000001071 188.0
HFD3_k127_6612381_5 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000006677 184.0
HFD3_k127_6612381_6 diguanylate cyclase - - - 0.000000000000000000000000000000000001471 151.0
HFD3_k127_6612381_7 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.0000000000000000000000000000000001601 149.0
HFD3_k127_6612381_8 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000000001005 93.0
HFD3_k127_6612381_9 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000001769 74.0
HFD3_k127_6615901_0 PQQ-like domain - - - 1.376e-197 640.0
HFD3_k127_6615901_1 C-methyltransferase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 485.0
HFD3_k127_6615901_2 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 474.0
HFD3_k127_6615901_3 cyclopropane-fatty-acyl-phospholipid synthase K00574,K18827 - 2.1.1.294,2.1.1.79,2.7.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 456.0
HFD3_k127_6615901_4 TIGRFAM glucose-1-phosphate cytidylyltransferase K00978 - 2.7.7.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 436.0
HFD3_k127_6615901_5 C-methyltransferase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 342.0
HFD3_k127_6615901_6 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 311.0
HFD3_k127_6615901_7 Glycosyltransferase family 10 (fucosyltransferase) C-term K20151 - 2.4.1.152,2.4.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000324 249.0
HFD3_k127_6615901_8 transferase activity, transferring glycosyl groups K12994 - 2.4.1.349 0.000000000000000000000000000000000000000001527 164.0
HFD3_k127_6617211_0 Fibronectin type 3 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002854 244.0
HFD3_k127_6617211_1 Serine/Threonine protein kinases, catalytic domain K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.0000000000000000000000000000003836 134.0
HFD3_k127_6654765_0 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 341.0
HFD3_k127_6654765_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000001209 132.0
HFD3_k127_6654765_2 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.00004554 52.0
HFD3_k127_6654765_3 - - - - 0.0007654 48.0
HFD3_k127_6657120_0 Cytochrome C and Quinol oxidase polypeptide I K15862 - 1.9.3.1 0.0 1073.0
HFD3_k127_6657120_1 Putative metal-binding domain of cation transport ATPase K01533 - 3.6.3.4 4.36e-235 754.0
HFD3_k127_6657120_10 ATP-grasp domain - - - 0.000000000000000000000000000000004024 137.0
HFD3_k127_6657120_11 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000001949 135.0
HFD3_k127_6657120_12 FixH - - - 0.000000000000000000000000000002971 127.0
HFD3_k127_6657120_13 Universal stress protein - - - 0.000000000000000000002743 101.0
HFD3_k127_6657120_14 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000003294 98.0
HFD3_k127_6657120_15 Universal stress protein - - - 0.0000000000000000004235 93.0
HFD3_k127_6657120_16 YCII-related domain K09780 - - 0.0000000000002014 82.0
HFD3_k127_6657120_17 COG3806 Anti-sigma factor - - - 0.0000000000008065 78.0
HFD3_k127_6657120_18 Catalyzes the synthesis of activated sulfate K00860 - 2.7.1.25 0.0000000003198 72.0
HFD3_k127_6657120_19 ChrR Cupin-like domain - - - 0.000000001374 68.0
HFD3_k127_6657120_2 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007649 498.0
HFD3_k127_6657120_20 Cytochrome c - - - 0.00000002558 61.0
HFD3_k127_6657120_22 Cytochrome oxidase maturation protein - - - 0.0000008593 61.0
HFD3_k127_6657120_23 AMP binding - - - 0.000001066 61.0
HFD3_k127_6657120_24 Belongs to the universal stress protein A family - - - 0.00003664 51.0
HFD3_k127_6657120_3 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007342 504.0
HFD3_k127_6657120_4 Short-chain dehydrogenase reductase (SDR) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002507 279.0
HFD3_k127_6657120_5 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.000000000000000000000000000000000000000000000000001813 189.0
HFD3_k127_6657120_6 Universal stress protein family - - - 0.00000000000000000000000000000000000000000001053 166.0
HFD3_k127_6657120_7 Sarcosine oxidase K00301 - 1.5.3.1 0.000000000000000000000000000000000000000006134 174.0
HFD3_k127_6657120_8 Adenylylsulphate kinase K00860 - 2.7.1.25 0.00000000000000000000000000000000000000001434 167.0
HFD3_k127_6657120_9 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000000000000001452 164.0
HFD3_k127_6672422_0 amine dehydrogenase activity K03418 - 3.5.1.56 1.99e-257 813.0
HFD3_k127_6672422_1 PFAM Alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 613.0
HFD3_k127_6672422_2 cyclase dehydrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002469 292.0
HFD3_k127_6672422_3 Short chain dehydrogenase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000001313 274.0
HFD3_k127_6672422_4 Amidohydrolase K03392,K22213 - 4.1.1.45,4.1.1.52 0.000000000000000000000000000000000000000000000000000004647 205.0
HFD3_k127_6672422_5 PFAM Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000001512 193.0
HFD3_k127_6672422_6 AAA domain - - - 0.000000000000000000000000000000000000071 147.0
HFD3_k127_6672422_7 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.000000000000000000000003522 107.0
HFD3_k127_6698750_0 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 526.0
HFD3_k127_6698750_1 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 486.0
HFD3_k127_6698750_10 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000005143 181.0
HFD3_k127_6698750_11 hydrolase of the alpha beta superfamily K07018 - - 0.00000000000000000000000000000000000000006712 159.0
HFD3_k127_6698750_12 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.0000000000000000000000000000000000519 138.0
HFD3_k127_6698750_13 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000006355 150.0
HFD3_k127_6698750_14 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000009488 129.0
HFD3_k127_6698750_15 - - - - 0.000000000000000000005315 106.0
HFD3_k127_6698750_16 Outer membrane lipoprotein - - - 0.000000000000000001965 98.0
HFD3_k127_6698750_17 - - - - 0.000000000000000003745 98.0
HFD3_k127_6698750_18 DNA methylase K00571,K00590 - 2.1.1.113,2.1.1.72 0.000000000003168 79.0
HFD3_k127_6698750_19 COG0810 Periplasmic protein TonB, links inner and outer membranes K03832 - - 0.000002212 60.0
HFD3_k127_6698750_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 478.0
HFD3_k127_6698750_21 KR domain K00034 - 1.1.1.47 0.0001929 48.0
HFD3_k127_6698750_22 - - - - 0.0009213 51.0
HFD3_k127_6698750_3 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 402.0
HFD3_k127_6698750_4 Binding-protein-dependent transport system inner membrane component K02033,K15585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008012 372.0
HFD3_k127_6698750_5 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K03438,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009249,GO:0009898,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006247 325.0
HFD3_k127_6698750_6 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003715 318.0
HFD3_k127_6698750_7 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009108 299.0
HFD3_k127_6698750_8 Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000005844 233.0
HFD3_k127_6698750_9 MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000000000001257 194.0
HFD3_k127_676166_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 4.372e-285 896.0
HFD3_k127_676166_1 AMP-dependent synthetase - - - 1.365e-253 811.0
HFD3_k127_676166_10 DNA polymerase K02347 - - 0.000000000000000000000000000000000000186 153.0
HFD3_k127_676166_11 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000003435 145.0
HFD3_k127_676166_12 GYD domain - - - 0.0000000000000000000000000000002124 127.0
HFD3_k127_676166_13 Cbs domain K04767 - - 0.00000000000000000000001551 109.0
HFD3_k127_676166_15 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000004333 99.0
HFD3_k127_676166_16 Universal stress protein K06149 - - 0.00000000000000002313 89.0
HFD3_k127_676166_17 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.000000000000001748 81.0
HFD3_k127_676166_2 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 1.501e-205 651.0
HFD3_k127_676166_3 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 434.0
HFD3_k127_676166_4 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009397 415.0
HFD3_k127_676166_5 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006421 324.0
HFD3_k127_676166_6 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 307.0
HFD3_k127_676166_7 two-component system sensor protein - - - 0.000000000000000000000000000000000000000000000000000000000000007806 232.0
HFD3_k127_676166_8 bacterial OsmY and nodulation domain - - - 0.0000000000000000000000000000000000000000000000000231 200.0
HFD3_k127_676166_9 Universal stress protein family - - - 0.00000000000000000000000000000000000000000002083 165.0
HFD3_k127_676293_0 PFAM Aldehyde oxidase xanthine dehydrogenase, molybdopterin binding K07303 - 1.3.99.16 0.0 1152.0
HFD3_k127_676293_1 PQQ-like domain K00114 - 1.1.2.8 1.222e-243 771.0
HFD3_k127_676293_10 Di-iron-containing protein involved in the repair of iron-sulfur clusters - - - 0.0000000000006433 81.0
HFD3_k127_676293_2 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 317.0
HFD3_k127_676293_3 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000004018 257.0
HFD3_k127_676293_4 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000007231 171.0
HFD3_k127_676293_5 - - - - 0.00000000000000000000000000000000000000000004496 163.0
HFD3_k127_676293_6 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000001766 175.0
HFD3_k127_676293_7 Evidence 5 No homology to any previously reported sequences K07156,K07245,K14166 - - 0.000000000000000000000000000000000000004342 162.0
HFD3_k127_676293_8 Evidence 5 No homology to any previously reported sequences K07156,K07245,K14166 - - 0.00000000000000000000000000000009679 133.0
HFD3_k127_676293_9 ubiE/COQ5 methyltransferase family - - - 0.0000000000000001352 90.0
HFD3_k127_6777495_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0 1327.0
HFD3_k127_6777495_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1027.0
HFD3_k127_6777495_10 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002217 287.0
HFD3_k127_6777495_11 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005532 270.0
HFD3_k127_6777495_12 Phenylacetic acid catabolic protein K02609 - 1.14.13.149 0.000000000000000000000000000000000000000000000000000000000000000000000002304 253.0
HFD3_k127_6777495_13 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000001053 184.0
HFD3_k127_6777495_14 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000001482 184.0
HFD3_k127_6777495_15 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000006465 154.0
HFD3_k127_6777495_16 Polymer-forming cytoskeletal - - - 0.0000000000000000000002305 105.0
HFD3_k127_6777495_2 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 1.023e-251 790.0
HFD3_k127_6777495_3 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 1.539e-199 653.0
HFD3_k127_6777495_4 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 511.0
HFD3_k127_6777495_5 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 505.0
HFD3_k127_6777495_6 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 419.0
HFD3_k127_6777495_7 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 387.0
HFD3_k127_6777495_8 Permease YjgP YjgQ family protein K07091,K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000075 308.0
HFD3_k127_6777495_9 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003839 283.0
HFD3_k127_6779706_0 Acyl-CoA dehydrogenase, middle domain K00249 - 1.3.8.7 6.783e-276 858.0
HFD3_k127_6779706_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 3e-263 823.0
HFD3_k127_6779706_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 1.289e-254 797.0
HFD3_k127_6779706_3 Amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 602.0
HFD3_k127_6779706_4 non-haem dioxygenase in morphine synthesis N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 407.0
HFD3_k127_6779706_5 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000297 267.0
HFD3_k127_6779706_6 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009107 253.0
HFD3_k127_6779706_7 Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA. It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base. The complementary strand guanine functions in substrate recognition. Required for DNA damage lesion repair in stationary-phase cells K03649 - 3.2.2.28 0.0000000000000000000000000000000000000000000000001497 185.0
HFD3_k127_6779706_8 von Willebrand factor (vWF) type A domain K07114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000009881 50.0
HFD3_k127_6861323_0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal - - - 0.000000000000000000000000000000000000001686 151.0
HFD3_k127_6861323_1 Yhs domain-containing protein - - - 0.0000000000000000000000000000000000001728 147.0
HFD3_k127_6861323_2 Redoxin - - - 0.0000000000004073 79.0
HFD3_k127_6861323_4 Disulphide bond corrector protein DsbC K04084 - 1.8.1.8 0.00005813 54.0
HFD3_k127_694637_0 overlaps another CDS with the same product name - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005576 380.0
HFD3_k127_694637_1 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002835 257.0
HFD3_k127_694637_2 acetylesterase activity K01046 - 3.1.1.3 0.000000000000000000000000000000000000000000000000000000007387 224.0
HFD3_k127_694637_3 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases - - - 0.000000000000000000000000000000000000358 145.0
HFD3_k127_7009943_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1274.0
HFD3_k127_7009943_1 COG0747 ABC-type dipeptide transport system, periplasmic component K02035 - - 8.983e-204 656.0
HFD3_k127_7009943_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 327.0
HFD3_k127_7009943_11 Thioesterase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004367 299.0
HFD3_k127_7009943_12 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 302.0
HFD3_k127_7009943_13 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001036 291.0
HFD3_k127_7009943_14 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002641 295.0
HFD3_k127_7009943_15 phosphorelay sensor kinase activity K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000345 261.0
HFD3_k127_7009943_16 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000007069 219.0
HFD3_k127_7009943_17 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000004015 207.0
HFD3_k127_7009943_18 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000001451 198.0
HFD3_k127_7009943_19 PFAM Phosphoglycerate mutase - - - 0.000000000000000000000000000000000000000000000006881 184.0
HFD3_k127_7009943_2 PFAM Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005369 629.0
HFD3_k127_7009943_20 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.000000000000000000000000000000000000000005563 170.0
HFD3_k127_7009943_21 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000003906 141.0
HFD3_k127_7009943_22 Alpha/beta hydrolase family - - - 0.000000000000000000000003024 106.0
HFD3_k127_7009943_23 SNARE-like domain protein - - - 0.000000000000000000003739 103.0
HFD3_k127_7009943_3 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 452.0
HFD3_k127_7009943_4 ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 423.0
HFD3_k127_7009943_5 Belongs to the ABC transporter superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 416.0
HFD3_k127_7009943_6 Belongs to the ABC transporter superfamily K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 419.0
HFD3_k127_7009943_7 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 410.0
HFD3_k127_7009943_8 PFAM Alcohol dehydrogenase zinc-binding domain protein K00001,K07119 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 384.0
HFD3_k127_7009943_9 fad dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 386.0
HFD3_k127_7034597_0 Glutamate synthase central domain K00265,K00284 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2179.0
HFD3_k127_7034597_1 Flavin containing amine oxidoreductase K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 9.752e-255 792.0
HFD3_k127_7034597_10 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 407.0
HFD3_k127_7034597_11 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 383.0
HFD3_k127_7034597_12 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 293.0
HFD3_k127_7034597_13 COG0583 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002133 281.0
HFD3_k127_7034597_14 peroxidase activity K00435 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006452 281.0
HFD3_k127_7034597_15 FAD binding domain K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005822 271.0
HFD3_k127_7034597_16 Cysteine-rich domain K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001291 253.0
HFD3_k127_7034597_17 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000000000000001437 170.0
HFD3_k127_7034597_18 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000006024 166.0
HFD3_k127_7034597_19 transmembrane transport K03442 - - 0.00000000000000000000000000000000003847 141.0
HFD3_k127_7034597_2 Pyruvate flavodoxin ferredoxin K00174 - 1.2.7.11,1.2.7.3 2.638e-237 748.0
HFD3_k127_7034597_20 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00363,K05710 - 1.7.1.15 0.000000000000000000000000003502 121.0
HFD3_k127_7034597_21 Cupin domain - - - 0.0000000000000000000000001083 113.0
HFD3_k127_7034597_22 LUD domain K00782,K18929 - - 0.000000000000000000000002525 120.0
HFD3_k127_7034597_23 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000007927 89.0
HFD3_k127_7034597_24 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.000000000000002676 88.0
HFD3_k127_7034597_25 - - - - 0.0000002636 56.0
HFD3_k127_7034597_26 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000007138 53.0
HFD3_k127_7034597_3 Gaf domain - - - 1.029e-201 659.0
HFD3_k127_7034597_4 FAD linked oxidases, C-terminal domain K00102,K00104 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.2.4,1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 528.0
HFD3_k127_7034597_5 Domain of unknown function (DUF3390) K18929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 476.0
HFD3_k127_7034597_6 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 456.0
HFD3_k127_7034597_7 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009981 460.0
HFD3_k127_7034597_8 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005917 428.0
HFD3_k127_7034597_9 Cysteine-rich domain K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 424.0
HFD3_k127_7050750_0 Glycosyl hydrolases family 15 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006962 524.0
HFD3_k127_7050750_1 His Kinase A (phosphoacceptor) domain - - - 0.00000001689 62.0
HFD3_k127_7092074_0 High confidence in function and specificity - - - 1.126e-274 865.0
HFD3_k127_7092074_1 Domain of unknown function (DUF3459) K01236 - 3.2.1.141 3.169e-268 847.0
HFD3_k127_7092074_10 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006232 409.0
HFD3_k127_7092074_11 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009309 400.0
HFD3_k127_7092074_12 acetyl-coa acetyltransferase K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 396.0
HFD3_k127_7092074_13 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007805 385.0
HFD3_k127_7092074_14 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 344.0
HFD3_k127_7092074_15 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006025 328.0
HFD3_k127_7092074_16 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 321.0
HFD3_k127_7092074_17 YmdB-like protein K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 312.0
HFD3_k127_7092074_18 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002674 273.0
HFD3_k127_7092074_19 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008652 273.0
HFD3_k127_7092074_2 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 4.074e-215 683.0
HFD3_k127_7092074_20 Putative transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001414 272.0
HFD3_k127_7092074_21 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001614 270.0
HFD3_k127_7092074_22 Phage integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000009942 250.0
HFD3_k127_7092074_23 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000002274 204.0
HFD3_k127_7092074_24 oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000005818 205.0
HFD3_k127_7092074_25 - - - - 0.0000000000000000000000000000000000000000000000004924 181.0
HFD3_k127_7092074_26 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000974 192.0
HFD3_k127_7092074_27 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.0000000000000000000000000000000000000002075 153.0
HFD3_k127_7092074_28 intermembrane phospholipid transfer K07323 - - 0.0000000000000000000000000000000000001013 152.0
HFD3_k127_7092074_29 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.000000000000000000000000000000000000299 146.0
HFD3_k127_7092074_3 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 2.14e-208 675.0
HFD3_k127_7092074_30 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000003102 143.0
HFD3_k127_7092074_31 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000005323 134.0
HFD3_k127_7092074_32 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000005529 132.0
HFD3_k127_7092074_34 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.00000000000000000000000001369 118.0
HFD3_k127_7092074_35 Dienelactone hydrolase - - - 0.000000000000000000000001923 116.0
HFD3_k127_7092074_36 Recombinase K06400 - - 0.0000000000000000000003409 98.0
HFD3_k127_7092074_37 ATPase activity K16922 - - 0.000000000000000000001085 110.0
HFD3_k127_7092074_38 Transposase - - - 0.000000000000000000001119 97.0
HFD3_k127_7092074_39 helix_turn_helix, cAMP Regulatory protein K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.00000000000000000002378 96.0
HFD3_k127_7092074_4 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 562.0
HFD3_k127_7092074_40 Transposase IS116/IS110/IS902 family K07486 - - 0.00000000000000000002734 94.0
HFD3_k127_7092074_41 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000006214 101.0
HFD3_k127_7092074_42 Belongs to the 'phage' integrase family - - - 0.00000000000000001538 95.0
HFD3_k127_7092074_43 domain protein - - - 0.0000000000000000499 92.0
HFD3_k127_7092074_44 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000008793 80.0
HFD3_k127_7092074_45 PFAM transposase IS116 IS110 IS902 family - - - 0.000000000000005159 83.0
HFD3_k127_7092074_46 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000003941 74.0
HFD3_k127_7092074_47 Cbs domain K04767 - - 0.0000000000003201 75.0
HFD3_k127_7092074_48 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000008255 72.0
HFD3_k127_7092074_49 Integrase core domain - - - 0.000000000001482 79.0
HFD3_k127_7092074_5 Endoribonuclease that initiates mRNA decay K18682 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 518.0
HFD3_k127_7092074_50 - - - - 0.000000000003589 78.0
HFD3_k127_7092074_51 Transposase zinc-binding domain - - - 0.00000000007596 74.0
HFD3_k127_7092074_52 energy transducer activity K03832 - - 0.0000000009287 70.0
HFD3_k127_7092074_53 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000001302 63.0
HFD3_k127_7092074_54 Flavin-binding monooxygenase-like K03379 - 1.14.13.22 0.00000008171 64.0
HFD3_k127_7092074_55 - - - - 0.0000001353 59.0
HFD3_k127_7092074_58 F420H(2)-dependent quinone reductase - - - 0.00001043 49.0
HFD3_k127_7092074_59 cell cycle K05589,K13052 - - 0.0001912 50.0
HFD3_k127_7092074_6 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 535.0
HFD3_k127_7092074_60 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.000695 46.0
HFD3_k127_7092074_61 Cellulose synthase K00694 - 2.4.1.12 0.0007708 52.0
HFD3_k127_7092074_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005369 490.0
HFD3_k127_7092074_8 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 466.0
HFD3_k127_7092074_9 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004396 469.0
HFD3_k127_7092279_0 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 446.0
HFD3_k127_7092279_1 F420-dependent oxidoreductase, MSMEG_3544 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 300.0
HFD3_k127_7092279_2 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002236 278.0
HFD3_k127_7092279_3 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001397 265.0
HFD3_k127_7092279_4 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007684 253.0
HFD3_k127_7092279_5 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000008905 235.0
HFD3_k127_7092279_6 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000009152 213.0
HFD3_k127_7092279_7 Belongs to the CDS family - - - 0.00000000000000000000000004275 110.0
HFD3_k127_7092279_8 alpha, beta - - - 0.00000000003396 70.0
HFD3_k127_7092279_9 Alpha/beta hydrolase family - - - 0.00000003136 61.0
HFD3_k127_7112065_0 PFAM FAD linked oxidase domain protein K00102,K00104 - 1.1.2.4,1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 561.0
HFD3_k127_7112065_1 4fe-4S ferredoxin, iron-sulfur binding domain protein K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006635 426.0
HFD3_k127_7112065_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003257 277.0
HFD3_k127_7112065_3 PFAM FAD binding domain K11472 - - 0.00000000000000000000000000000000000000000000000000000000000000005638 241.0
HFD3_k127_7112065_4 Mo-molybdopterin cofactor metabolic process K03638 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000001293 211.0
HFD3_k127_7112065_5 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000004819 130.0
HFD3_k127_7112065_6 glycosyl transferase family 39 K00721 - 2.4.1.83 0.00000000000000000002611 108.0
HFD3_k127_7112065_7 nitrite reductase [NAD(P)H] activity K00363,K05710 - 1.7.1.15 0.00000000000000002264 94.0
HFD3_k127_7112065_8 Protein of unknown function, DUF255 K06888 - - 0.00000000000002643 75.0
HFD3_k127_7112065_9 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00001065 52.0
HFD3_k127_7132321_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K17050 - 1.7.5.1,1.8.5.3 0.0 1170.0
HFD3_k127_7132321_1 nitrate reductase beta subunit K00371,K17051 - 1.7.5.1 1.491e-200 668.0
HFD3_k127_7132321_10 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000007373 179.0
HFD3_k127_7132321_11 Pyruvate phosphate dikinase - - - 0.000000000000000000000000000000000000000000962 162.0
HFD3_k127_7132321_12 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000000000000216 150.0
HFD3_k127_7132321_13 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000001248 115.0
HFD3_k127_7132321_14 chaperone-mediated protein complex assembly - - - 0.0000000000000000000005244 106.0
HFD3_k127_7132321_15 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104,K03325,K03741,K03892,K18701 - 1.20.4.1,2.8.4.2,3.1.3.48 0.000000000000000000001682 110.0
HFD3_k127_7132321_16 Cupin 2, conserved barrel domain protein - - - 0.000000000000000001013 94.0
HFD3_k127_7132321_17 Belongs to the 'phage' integrase family - - - 0.000000000001718 76.0
HFD3_k127_7132321_18 Evidence 4 Homologs of previously reported genes of - - - 0.0000000001016 66.0
HFD3_k127_7132321_19 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.0000003196 57.0
HFD3_k127_7132321_2 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006011 415.0
HFD3_k127_7132321_20 transcriptional regulator - - - 0.0003961 46.0
HFD3_k127_7132321_3 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 400.0
HFD3_k127_7132321_4 chaperone-mediated protein complex assembly - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 308.0
HFD3_k127_7132321_5 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 301.0
HFD3_k127_7132321_6 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000002779 229.0
HFD3_k127_7132321_7 Transposase K07481 - - 0.000000000000000000000000000000000000000000000000004116 192.0
HFD3_k127_7132321_9 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000003859 194.0
HFD3_k127_7136110_0 PFAM acyl-CoA dehydrogenase domain protein K00255,K11731 - 1.3.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 533.0
HFD3_k127_7136110_1 Acyl- CoA dehydrogenase type 2 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 397.0
HFD3_k127_7136110_10 transporter antisigma-factor antagonist STAS K17762 - - 0.0000000000000000000000000000000000000000000001991 171.0
HFD3_k127_7136110_11 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000000008112 152.0
HFD3_k127_7136110_12 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000005175 122.0
HFD3_k127_7136110_13 Glyoxalase-like domain K04750 - - 0.000000000000000000000007555 113.0
HFD3_k127_7136110_14 - - - - 0.000000000000000001812 86.0
HFD3_k127_7136110_2 SAICAR synthetase K01923,K01945 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 352.0
HFD3_k127_7136110_3 Anti-anti sigma factor protein K17763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009095 325.0
HFD3_k127_7136110_4 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749,K18702 - 2.8.3.16,2.8.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003885 310.0
HFD3_k127_7136110_5 DJ-1/PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000005388 245.0
HFD3_k127_7136110_6 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000001537 244.0
HFD3_k127_7136110_7 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000004802 217.0
HFD3_k127_7136110_8 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000007205 181.0
HFD3_k127_7136110_9 PFAM ATP-binding region, ATPase domain protein K17752 - 2.7.11.1 0.0000000000000000000000000000000000000000000001823 171.0
HFD3_k127_7164695_0 lipopolysaccharide transport K22110 - - 0.0 1284.0
HFD3_k127_7164695_1 choline dehydrogenase activity - - - 1.028e-266 833.0
HFD3_k127_7164695_10 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.00000000000000000000000000000000000000000000000000000000001877 216.0
HFD3_k127_7164695_11 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000207 224.0
HFD3_k127_7164695_12 Uncharacterised nucleotidyltransferase - - - 0.000000000000000000000000000000000000000000000000000002969 216.0
HFD3_k127_7164695_13 Methylmuconolactone methyl-isomerase - - - 0.00000000000000000000000000000000000000000000000000001072 198.0
HFD3_k127_7164695_14 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000285 177.0
HFD3_k127_7164695_15 Patatin-like phospholipase K07001 - - 0.000001216 61.0
HFD3_k127_7164695_16 Glycosyl transferases group 1 K20444 - - 0.000002515 51.0
HFD3_k127_7164695_17 Cold shock K03704 - - 0.0007833 48.0
HFD3_k127_7164695_2 alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 543.0
HFD3_k127_7164695_3 type I phosphodiesterase nucleotide pyrophosphatase K19670 - 3.11.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006979 521.0
HFD3_k127_7164695_4 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 427.0
HFD3_k127_7164695_5 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 409.0
HFD3_k127_7164695_6 SMP-30/Gluconolaconase/LRE-like region K14274 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004726 374.0
HFD3_k127_7164695_7 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01781 - 5.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 320.0
HFD3_k127_7164695_8 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001143 274.0
HFD3_k127_7164695_9 5-formyltetrahydrofolate cycloligase K01934 - 6.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000002138 248.0
HFD3_k127_7168900_0 COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM CutM homologs K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 327.0
HFD3_k127_7168900_1 Ketopantoate reductase PanE/ApbA C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001031 261.0
HFD3_k127_7168900_2 sigma factor activity K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000001033 233.0
HFD3_k127_7168900_3 Protein of unknown function (DUF2384) K15359 - 1.14.13.163 0.000004993 57.0
HFD3_k127_7168900_4 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0004168 52.0
HFD3_k127_7172197_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1641.0
HFD3_k127_7172197_1 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K09181 - - 0.0 1129.0
HFD3_k127_7172197_10 PFAM amidohydrolase 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 354.0
HFD3_k127_7172197_11 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.0000000000000000000000000000000000000000000000000000000000000008784 226.0
HFD3_k127_7172197_12 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.0000000000000000000000000000000000000000000000000000009749 194.0
HFD3_k127_7172197_13 serine-type endopeptidase activity - - - 0.000000000000000000000000000000000006199 150.0
HFD3_k127_7172197_14 lactate metabolic process - - - 0.0000000000000000000000000000000005203 147.0
HFD3_k127_7172197_15 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) - - - 0.00000000000000000000000000000003092 142.0
HFD3_k127_7172197_16 Protein of unknown function (DUF1272) - - - 0.00000000000000000000000000001844 138.0
HFD3_k127_7172197_17 N-methylhydantoinase A acetone carboxylase, beta subunit K01473 - 3.5.2.14 0.00000000000000000000000003211 112.0
HFD3_k127_7172197_18 Bacterial regulatory proteins, tetR family - - - 0.0000000000000002049 88.0
HFD3_k127_7172197_19 - - - - 0.000000000001163 80.0
HFD3_k127_7172197_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 2.708e-252 797.0
HFD3_k127_7172197_3 Cytochrome c K00428 - 1.11.1.5 5.027e-247 773.0
HFD3_k127_7172197_4 Resolvase, RNase H domain protein fold K06959 - - 4.782e-199 647.0
HFD3_k127_7172197_5 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 507.0
HFD3_k127_7172197_6 Transport permease protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 421.0
HFD3_k127_7172197_7 PFAM secretion protein HlyD family protein K01993,K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 410.0
HFD3_k127_7172197_8 PFAM Rhodanese domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004367 370.0
HFD3_k127_7172197_9 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003837 368.0
HFD3_k127_7174970_0 Hydantoinase B/oxoprolinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 598.0
HFD3_k127_7174970_1 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003924 552.0
HFD3_k127_7174970_2 domain, Protein - - - 0.00008729 50.0
HFD3_k127_718913_0 acyl-CoA dehydrogenase activity K00248,K00253 - 1.3.8.1,1.3.8.4 0.00000000000000000000000000000000000000000000000000000000007547 226.0
HFD3_k127_718913_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000002591 215.0
HFD3_k127_718913_2 dehydratase - - - 0.000000000000000000000000000000000000000000000001855 197.0
HFD3_k127_718913_3 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087 - 0.00000000000002162 78.0
HFD3_k127_7194527_0 helicase activity - - - 0.0 1044.0
HFD3_k127_7194527_1 Transglycosylase - - - 1.687e-313 992.0
HFD3_k127_7194527_10 Binding-protein-dependent transport system inner membrane component K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006104 376.0
HFD3_k127_7194527_11 Binding-protein-dependent transport system inner membrane component K02053 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 357.0
HFD3_k127_7194527_12 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 336.0
HFD3_k127_7194527_13 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 346.0
HFD3_k127_7194527_14 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 339.0
HFD3_k127_7194527_15 Extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 334.0
HFD3_k127_7194527_16 PFAM Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 313.0
HFD3_k127_7194527_17 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 299.0
HFD3_k127_7194527_18 Ketopantoate reductase PanE/ApbA C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008264 289.0
HFD3_k127_7194527_19 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001261 287.0
HFD3_k127_7194527_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.741e-285 894.0
HFD3_k127_7194527_20 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000004368 210.0
HFD3_k127_7194527_21 Belongs to the Nudix hydrolase family - - - 0.0000000000000000000000000000000000000000000000001203 194.0
HFD3_k127_7194527_22 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000001877 173.0
HFD3_k127_7194527_23 - K09957 - - 0.00000000000000000000000000000000000001396 167.0
HFD3_k127_7194527_24 - - - - 0.0000000000000000000000191 105.0
HFD3_k127_7194527_25 Methyltransferase domain - - - 0.0000000001636 69.0
HFD3_k127_7194527_26 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000007811 56.0
HFD3_k127_7194527_3 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652,K03852 - 2.2.1.6,2.3.3.15 1.615e-251 790.0
HFD3_k127_7194527_4 Luciferase-like monooxygenase - - - 1.442e-215 676.0
HFD3_k127_7194527_5 COG1840 ABC-type Fe3 transport system, periplasmic component K02055 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 523.0
HFD3_k127_7194527_6 Alanine dehydrogenase/PNT, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 519.0
HFD3_k127_7194527_7 P-aminobenzoate N-oxygenase AurF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009178 513.0
HFD3_k127_7194527_8 Belongs to the ABC transporter superfamily K02052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 454.0
HFD3_k127_7194527_9 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007012 427.0
HFD3_k127_7240558_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.0 1285.0
HFD3_k127_7240558_1 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003571 614.0
HFD3_k127_7240558_10 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000002226 242.0
HFD3_k127_7240558_11 ABC-type branched-chain amino acid transport K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000001745 242.0
HFD3_k127_7240558_12 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000004305 218.0
HFD3_k127_7240558_13 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000005145 123.0
HFD3_k127_7240558_14 - - - - 0.0000000000000000000000003523 111.0
HFD3_k127_7240558_15 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000001572 108.0
HFD3_k127_7240558_16 Universal stress protein family - - - 0.000000000000000000005331 103.0
HFD3_k127_7240558_17 zinc ion binding K06204 - - 0.00000000000404 71.0
HFD3_k127_7240558_18 Alcohol dehydrogenase GroES-like domain - - - 0.00007058 50.0
HFD3_k127_7240558_2 N-methylhydantoinase B acetone carboxylase, alpha subunit K01474 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 518.0
HFD3_k127_7240558_3 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 450.0
HFD3_k127_7240558_4 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 427.0
HFD3_k127_7240558_5 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 396.0
HFD3_k127_7240558_6 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008552 273.0
HFD3_k127_7240558_7 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004965 250.0
HFD3_k127_7240558_8 Mut7-C ubiquitin K09122 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000989 252.0
HFD3_k127_7240558_9 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000002626 250.0
HFD3_k127_725966_0 DNA topoisomerase II activity K03167 - 5.99.1.3 4.898e-290 901.0
HFD3_k127_725966_1 DNA-K related protein - - - 3.012e-215 699.0
HFD3_k127_725966_10 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003887 284.0
HFD3_k127_725966_11 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001083 257.0
HFD3_k127_725966_12 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000007422 243.0
HFD3_k127_725966_13 Bacterial regulatory proteins, tetR family K16137 - - 0.0000000000000000000000000000000000000000000000000000000000000004799 226.0
HFD3_k127_725966_14 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000009197 225.0
HFD3_k127_725966_15 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000001289 226.0
HFD3_k127_725966_16 acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000002751 202.0
HFD3_k127_725966_17 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000000005876 177.0
HFD3_k127_725966_18 protein possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000000000000001806 152.0
HFD3_k127_725966_19 - - - - 0.00000000000000000000000000000000000000293 153.0
HFD3_k127_725966_2 MreB/Mbl protein - - - 1.286e-212 680.0
HFD3_k127_725966_20 17 kDa outer membrane surface antigen - - - 0.0000000000000000000000000000000000009703 145.0
HFD3_k127_725966_21 Domain of unknown function (DUF2760) - - - 0.000000000000000000000000000000000003163 144.0
HFD3_k127_725966_22 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000006464 144.0
HFD3_k127_725966_23 Cold shock protein K03704 - - 0.00000000000000000000000004663 113.0
HFD3_k127_725966_24 Acetyltransferase (GNAT) domain - - - 0.000000000000000000001027 103.0
HFD3_k127_725966_25 transferase activity, transferring glycosyl groups - - - 0.00000000000005343 72.0
HFD3_k127_725966_26 Luciferase-like monooxygenase - - - 0.0000000000003615 72.0
HFD3_k127_725966_27 EF-hand, calcium binding motif - - - 0.000006179 55.0
HFD3_k127_725966_3 DNA topoisomerase VI subunit A K03166 - 5.99.1.3 4.084e-202 632.0
HFD3_k127_725966_4 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006341 595.0
HFD3_k127_725966_5 MacB-like periplasmic core domain K02004,K05685 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006198 471.0
HFD3_k127_725966_6 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005996 355.0
HFD3_k127_725966_7 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 360.0
HFD3_k127_725966_8 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 335.0
HFD3_k127_725966_9 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 294.0
HFD3_k127_7280498_0 Zinc-binding dehydrogenase K00001 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004745 492.0
HFD3_k127_7280498_1 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 400.0
HFD3_k127_7280498_2 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002009 275.0
HFD3_k127_7280498_3 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000001798 189.0
HFD3_k127_7280498_4 Amidohydrolase family - - - 0.000000000000000000000000000000000000000002197 164.0
HFD3_k127_7280498_5 Evidence 4 Homologs of previously reported genes of K09700 - - 0.0000000000000000000000000000000054 133.0
HFD3_k127_7280498_6 EamA-like transporter family - - - 0.00000000000000000000001068 114.0
HFD3_k127_7288569_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 3.071e-282 890.0
HFD3_k127_7288569_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 - 2.7.6.5,3.1.7.2 3.36e-270 848.0
HFD3_k127_7288569_10 PFAM aminotransferase, class I K00812,K10907 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 462.0
HFD3_k127_7288569_11 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 437.0
HFD3_k127_7288569_12 Enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 393.0
HFD3_k127_7288569_13 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 385.0
HFD3_k127_7288569_14 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 360.0
HFD3_k127_7288569_15 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 351.0
HFD3_k127_7288569_16 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 360.0
HFD3_k127_7288569_17 Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 341.0
HFD3_k127_7288569_18 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007374 342.0
HFD3_k127_7288569_19 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006592 319.0
HFD3_k127_7288569_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding K00179 - 1.2.7.8 5.167e-257 809.0
HFD3_k127_7288569_20 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 295.0
HFD3_k127_7288569_21 SecD/SecF GG Motif K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008271 274.0
HFD3_k127_7288569_22 Proteasomal ATPase OB/ID domain K07184,K07777,K12065,K13525,K13527 GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000009489 265.0
HFD3_k127_7288569_23 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009216 267.0
HFD3_k127_7288569_24 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000002366 239.0
HFD3_k127_7288569_25 Belongs to the enoyl-CoA hydratase isomerase family K16880 - - 0.0000000000000000000000000000000000000000000000000000000000000001463 248.0
HFD3_k127_7288569_26 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000003138 236.0
HFD3_k127_7288569_27 PFAM ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000411 231.0
HFD3_k127_7288569_28 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000682 219.0
HFD3_k127_7288569_29 PFAM Stage II sporulation K06381 - - 0.00000000000000000000000000000000000000000000000000000007456 222.0
HFD3_k127_7288569_3 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 5.842e-221 706.0
HFD3_k127_7288569_30 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000417 192.0
HFD3_k127_7288569_31 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000002639 193.0
HFD3_k127_7288569_32 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000001953 171.0
HFD3_k127_7288569_33 Polyketide cyclase / dehydrase and lipid transport K09386 - - 0.0000000000000000000000000000000000000001515 155.0
HFD3_k127_7288569_34 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000002569 156.0
HFD3_k127_7288569_35 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000444 166.0
HFD3_k127_7288569_36 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000000000000000000002699 151.0
HFD3_k127_7288569_37 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000000000000000376 137.0
HFD3_k127_7288569_38 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000000005627 133.0
HFD3_k127_7288569_39 Belongs to the enoyl-CoA hydratase isomerase family K01692,K13766 - 4.2.1.17,4.2.1.18 0.0000000000000000000000000000001644 138.0
HFD3_k127_7288569_4 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003602 631.0
HFD3_k127_7288569_40 protein transport K03210 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000001825 107.0
HFD3_k127_7288569_41 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000153 100.0
HFD3_k127_7288569_42 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000000009207 98.0
HFD3_k127_7288569_43 Luciferase-like monooxygenase - - - 0.000000000000000000005591 99.0
HFD3_k127_7288569_44 Protein of unknown function (DUF2905) - - - 0.00000000000000000001328 93.0
HFD3_k127_7288569_45 PFAM Luciferase-like monooxygenase - - - 0.000004589 56.0
HFD3_k127_7288569_5 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007648 524.0
HFD3_k127_7288569_6 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 529.0
HFD3_k127_7288569_7 AMP-binding enzyme C-terminal domain K16876 - 6.2.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 522.0
HFD3_k127_7288569_8 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 511.0
HFD3_k127_7288569_9 PFAM multi antimicrobial extrusion protein MatE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003762 480.0
HFD3_k127_7289533_0 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005247 502.0
HFD3_k127_7289533_1 C-terminal AAA-associated domain K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 350.0
HFD3_k127_7289533_2 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000009039 201.0
HFD3_k127_7289533_3 integral membrane protein - - - 0.0001929 48.0
HFD3_k127_7326873_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005424 394.0
HFD3_k127_7326873_1 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005488 334.0
HFD3_k127_7326873_2 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001452 280.0
HFD3_k127_7326873_3 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000001848 199.0
HFD3_k127_7326873_4 peroxiredoxin activity K01607 - 4.1.1.44 0.000000000000000000000000000001571 123.0
HFD3_k127_7326873_5 O-methyltransferase - - - 0.00000000000000000000000001402 119.0
HFD3_k127_7326873_6 large terminal subunit of phenylpropionate dioxygenase K16319,K18242 - 1.14.12.1,1.14.13.172 0.000000000000000001713 90.0
HFD3_k127_7326873_7 PFAM ring hydroxylating dioxygenase, alpha subunit - - - 0.0000000000000002394 87.0
HFD3_k127_7326873_8 Domain of unknown function (DUF4129) - - - 0.000000002652 68.0
HFD3_k127_7326873_9 - - - - 0.0002252 51.0
HFD3_k127_7333118_0 Hydantoinase/oxoprolinase K01473 - 3.5.2.14 3.356e-282 883.0
HFD3_k127_7333118_1 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 1.122e-222 711.0
HFD3_k127_7333118_2 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 484.0
HFD3_k127_7333118_3 MmgE/PrpD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 314.0
HFD3_k127_7333118_4 PFAM Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000000000003249 232.0
HFD3_k127_7333118_5 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000005282 167.0
HFD3_k127_7333118_6 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000015 128.0
HFD3_k127_7355217_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 1.542e-211 681.0
HFD3_k127_7355217_1 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007758 552.0
HFD3_k127_7355217_10 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008929 268.0
HFD3_k127_7355217_11 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH - - - 0.00000000000000000000000000000000000000000000000000000000000000000005955 246.0
HFD3_k127_7355217_12 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000001249 231.0
HFD3_k127_7355217_13 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000009032 240.0
HFD3_k127_7355217_14 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000009828 222.0
HFD3_k127_7355217_15 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000002227 233.0
HFD3_k127_7355217_16 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000815 228.0
HFD3_k127_7355217_17 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000001689 235.0
HFD3_k127_7355217_18 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000001065 212.0
HFD3_k127_7355217_19 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000000000000000000000000000001206 204.0
HFD3_k127_7355217_2 UDP binding domain K02474,K13015 - 1.1.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 519.0
HFD3_k127_7355217_20 Formyl transferase - - - 0.000000000000000000000000000000000000000000000000002634 194.0
HFD3_k127_7355217_21 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.0000000000000000000000000000000000000000000006579 188.0
HFD3_k127_7355217_22 3-beta hydroxysteroid dehydrogenase isomerase K21793 - - 0.0000000000000000000000000000000000000000001416 177.0
HFD3_k127_7355217_23 PFAM Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000001419 179.0
HFD3_k127_7355217_24 ATP-grasp domain K01955 - 6.3.5.5 0.00000000000000000000000000000000000000001277 174.0
HFD3_k127_7355217_25 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000006717 158.0
HFD3_k127_7355217_26 - - - - 0.00000000000000000000000000000008577 125.0
HFD3_k127_7355217_27 CsbD-like - - - 0.0000000000000000000003083 100.0
HFD3_k127_7355217_28 Chain length determinant protein - - - 0.000000000000000000312 102.0
HFD3_k127_7355217_29 Bacterial extracellular solute-binding protein - - - 0.000000000000000007862 98.0
HFD3_k127_7355217_3 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004381 383.0
HFD3_k127_7355217_30 ATPase MipZ - - - 0.00000000000000005156 93.0
HFD3_k127_7355217_31 PFAM Peptidase family M48 - - - 0.000000000007583 76.0
HFD3_k127_7355217_32 O-Antigen ligase - - - 0.0004306 53.0
HFD3_k127_7355217_33 Domain present in carbohydrate binding proteins and sugar hydrolses K07218 - - 0.0006004 52.0
HFD3_k127_7355217_4 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 323.0
HFD3_k127_7355217_5 PFAM (2R)-phospho-3-sulfolactate synthase ComA K08097 - 4.4.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 306.0
HFD3_k127_7355217_6 PFAM (2R)-phospho-3-sulfolactate synthase ComA K08097 - 4.4.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000292 305.0
HFD3_k127_7355217_7 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000187 300.0
HFD3_k127_7355217_8 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008777 265.0
HFD3_k127_7355217_9 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005406 252.0
HFD3_k127_7360105_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 2.551e-213 680.0
HFD3_k127_7360105_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006 - 2.7.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 484.0
HFD3_k127_7360105_2 Belongs to the DapA family K01714,K22397 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0019520,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0047440,GO:0071704,GO:0072329,GO:1901575 4.1.2.28,4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000003622 239.0
HFD3_k127_7360105_3 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.000000000000000000000000000000000000000000000001799 178.0
HFD3_k127_7360105_4 ACT domain K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.000000000000000000000000000000005567 130.0
HFD3_k127_7377897_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 1.244e-298 924.0
HFD3_k127_7377897_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 6.021e-257 805.0
HFD3_k127_7377897_10 Dehydrogenase E1 component K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 410.0
HFD3_k127_7377897_11 Associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 400.0
HFD3_k127_7377897_12 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 373.0
HFD3_k127_7377897_13 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 365.0
HFD3_k127_7377897_14 Component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 343.0
HFD3_k127_7377897_15 Belongs to the dCTP deaminase family K01494 GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005109 312.0
HFD3_k127_7377897_16 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 291.0
HFD3_k127_7377897_17 Bacterial transferase hexapeptide (six repeats) K00640 GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016053,GO:0016054,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000001478 277.0
HFD3_k127_7377897_18 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008757 264.0
HFD3_k127_7377897_19 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000191 265.0
HFD3_k127_7377897_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 1.042e-224 713.0
HFD3_k127_7377897_20 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003148 257.0
HFD3_k127_7377897_21 PFAM Haloacid dehalogenase domain protein hydrolase K01560,K07025 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000002411 246.0
HFD3_k127_7377897_22 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000001558 236.0
HFD3_k127_7377897_23 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.00000000000000000000000000000000000000000000000000000000000000007168 224.0
HFD3_k127_7377897_24 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000003001 177.0
HFD3_k127_7377897_25 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000004276 166.0
HFD3_k127_7377897_26 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.000000000000000000000000000000000000001626 152.0
HFD3_k127_7377897_27 Transcriptional regulator - - - 0.0000000000000000000000000000000001313 137.0
HFD3_k127_7377897_28 Belongs to the HesB IscA family K13628 GO:0003674,GO:0005488,GO:0005506,GO:0005515,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:0097428,GO:1901564 - 0.00000000000000000000000000000007476 129.0
HFD3_k127_7377897_29 Thioredoxin-like - - - 0.00000000000000000000000000000463 131.0
HFD3_k127_7377897_3 Hsp70 protein K04043,K04044 - - 2.176e-218 693.0
HFD3_k127_7377897_30 DnaJ molecular chaperone homology domain K04082 - - 0.000000000000000000000000001776 120.0
HFD3_k127_7377897_31 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000001081 120.0
HFD3_k127_7377897_32 iron-sulfur cluster assembly - GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772 - 0.000000000000000000000000212 106.0
HFD3_k127_7377897_33 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE - - - 0.00000000000000000000002607 104.0
HFD3_k127_7377897_34 Glycosyl transferase family 41 K09667 GO:0000003,GO:0000123,GO:0000785,GO:0000791,GO:0001678,GO:0001932,GO:0001933,GO:0001934,GO:0002119,GO:0002164,GO:0002237,GO:0003674,GO:0003824,GO:0004721,GO:0004722,GO:0005488,GO:0005515,GO:0005543,GO:0005547,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0006040,GO:0006041,GO:0006047,GO:0006048,GO:0006073,GO:0006091,GO:0006109,GO:0006110,GO:0006111,GO:0006112,GO:0006139,GO:0006140,GO:0006325,GO:0006355,GO:0006357,GO:0006464,GO:0006470,GO:0006473,GO:0006475,GO:0006479,GO:0006486,GO:0006493,GO:0006508,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007444,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0007626,GO:0008080,GO:0008134,GO:0008150,GO:0008152,GO:0008194,GO:0008213,GO:0008219,GO:0008289,GO:0008361,GO:0008375,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009605,GO:0009607,GO:0009617,GO:0009636,GO:0009719,GO:0009725,GO:0009743,GO:0009746,GO:0009749,GO:0009791,GO:0009888,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009966,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010562,GO:0010563,GO:0010604,GO:0010605,GO:0010628,GO:0010638,GO:0010646,GO:0010675,GO:0010799,GO:0010801,GO:0010876,GO:0010906,GO:0010941,GO:0012501,GO:0012505,GO:0015980,GO:0016020,GO:0016043,GO:0016262,GO:0016311,GO:0016407,GO:0016410,GO:0016485,GO:0016569,GO:0016570,GO:0016571,GO:0016573,GO:0016579,GO:0016740,GO:0016746,GO:0016747,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0018022,GO:0018023,GO:0018130,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019725,GO:0019904,GO:0019915,GO:0022607,GO:0023051,GO:0023052,GO:0030141,GO:0030162,GO:0030246,GO:0030808,GO:0030811,GO:0030900,GO:0031056,GO:0031058,GO:0031060,GO:0031062,GO:0031248,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0031396,GO:0031397,GO:0031399,GO:0031400,GO:0031401,GO:0031410,GO:0031667,GO:0031974,GO:0031981,GO:0031982,GO:0032259,GO:0032268,GO:0032269,GO:0032270,GO:0032386,GO:0032387,GO:0032434,GO:0032435,GO:0032496,GO:0032501,GO:0032502,GO:0032535,GO:0032868,GO:0032869,GO:0032870,GO:0032879,GO:0032880,GO:0032922,GO:0032991,GO:0033036,GO:0033043,GO:0033044,GO:0033135,GO:0033137,GO:0033157,GO:0033218,GO:0033500,GO:0033993,GO:0034284,GO:0034641,GO:0034645,GO:0034654,GO:0034968,GO:0035020,GO:0035091,GO:0035220,GO:0035295,GO:0035556,GO:0036094,GO:0036211,GO:0036477,GO:0040024,GO:0042176,GO:0042177,GO:0042221,GO:0042277,GO:0042325,GO:0042326,GO:0042327,GO:0042578,GO:0042588,GO:0042592,GO:0042593,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043255,GO:0043412,GO:0043413,GO:0043414,GO:0043434,GO:0043467,GO:0043470,GO:0043543,GO:0043933,GO:0043967,GO:0043981,GO:0043982,GO:0043984,GO:0044042,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044271,GO:0044281,GO:0044297,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0045475,GO:0045793,GO:0045861,GO:0045862,GO:0045893,GO:0045935,GO:0045936,GO:0045937,GO:0045944,GO:0046349,GO:0046483,GO:0046578,GO:0046626,GO:0048015,GO:0048017,GO:0048029,GO:0048311,GO:0048312,GO:0048471,GO:0048511,GO:0048512,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051056,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051193,GO:0051196,GO:0051223,GO:0051224,GO:0051235,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051276,GO:0051291,GO:0051568,GO:0051604,GO:0051640,GO:0051641,GO:0051646,GO:0051704,GO:0051707,GO:0051716,GO:0055082,GO:0055086,GO:0055114,GO:0060255,GO:0060322,GO:0060341,GO:0060429,GO:0060548,GO:0061085,GO:0061087,GO:0061136,GO:0062012,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070085,GO:0070201,GO:0070206,GO:0070207,GO:0070208,GO:0070646,GO:0070647,GO:0070887,GO:0071216,GO:0071219,GO:0071222,GO:0071310,GO:0071322,GO:0071326,GO:0071331,GO:0071333,GO:0071375,GO:0071396,GO:0071417,GO:0071495,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0080182,GO:0090066,GO:0090087,GO:0090313,GO:0090315,GO:0090317,GO:0097237,GO:0097363,GO:0097458,GO:0097708,GO:0099503,GO:0120025,GO:0140096,GO:1900037,GO:1900038,GO:1900076,GO:1900180,GO:1900182,GO:1900371,GO:1900542,GO:1901071,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901799,GO:1901981,GO:1902275,GO:1902493,GO:1902494,GO:1902531,GO:1902680,GO:1903050,GO:1903051,GO:1903320,GO:1903321,GO:1903362,GO:1903363,GO:1903426,GO:1903428,GO:1903506,GO:1903508,GO:1903533,GO:1903578,GO:1903827,GO:1903828,GO:1903829,GO:1904950,GO:1905269,GO:1905475,GO:1905476,GO:1990234,GO:2000058,GO:2000059,GO:2000112,GO:2000377,GO:2000379,GO:2001141,GO:2001169,GO:2001252 2.4.1.255 0.0000000000000002043 92.0
HFD3_k127_7377897_36 Pup-like protein K13570 - - 0.0000000000004944 78.0
HFD3_k127_7377897_37 Putative zinc-finger - - - 0.00000000004691 66.0
HFD3_k127_7377897_38 Putative regulatory protein - - - 0.0000000004549 63.0
HFD3_k127_7377897_4 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 557.0
HFD3_k127_7377897_5 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 501.0
HFD3_k127_7377897_6 PFAM Pyridine nucleotide-disulphide oxidoreductase, FAD NAD(P)-binding domain, pyridine nucleotide-disulfide oxidoreductase dimerization region, FAD-dependent pyridine nucleotide-disulfide oxidoreductase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 513.0
HFD3_k127_7377897_7 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 540.0
HFD3_k127_7377897_8 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008054 454.0
HFD3_k127_7377897_9 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 445.0
HFD3_k127_7391425_0 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006009 340.0
HFD3_k127_7391425_1 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000001606 216.0
HFD3_k127_7391425_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000426 146.0
HFD3_k127_7411261_0 Belongs to the amidase family K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000969 412.0
HFD3_k127_7411261_1 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002055 252.0
HFD3_k127_7413732_0 4-hydroxyphenylacetate 3-hydroxylase C terminal - - - 2.113e-237 750.0
HFD3_k127_7413732_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.437e-236 749.0
HFD3_k127_7413732_10 Major Facilitator Superfamily - - - 0.0000000000000000000000005386 118.0
HFD3_k127_7413732_11 antibiotic biosynthesis - - - 0.0000000000000000000001018 110.0
HFD3_k127_7413732_12 Protein of unknown function (DUF861) - - - 0.0000000000000044 82.0
HFD3_k127_7413732_2 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006876 546.0
HFD3_k127_7413732_3 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 394.0
HFD3_k127_7413732_4 NMT1-like family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007428 388.0
HFD3_k127_7413732_5 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002923 286.0
HFD3_k127_7413732_6 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000000000000000000008512 173.0
HFD3_k127_7413732_7 SnoaL-like domain - - - 0.000000000000000000000000000000000000001424 153.0
HFD3_k127_7413732_8 Domain of unknown function (DUF1772) - - - 0.00000000000000000000000000000000002607 153.0
HFD3_k127_7413732_9 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000007875 121.0
HFD3_k127_7420428_0 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 533.0
HFD3_k127_7420428_1 AMP-binding enzyme C-terminal domain K00666,K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 453.0
HFD3_k127_7420428_2 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 357.0
HFD3_k127_7420428_3 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006549 327.0
HFD3_k127_7420428_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001491 257.0
HFD3_k127_7420428_5 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001692 243.0
HFD3_k127_7420428_6 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000001795 188.0
HFD3_k127_7420428_7 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000002083 84.0
HFD3_k127_7481599_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 522.0
HFD3_k127_7481599_1 Aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 496.0
HFD3_k127_7481599_10 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008784 289.0
HFD3_k127_7481599_11 Methylene-tetrahydrofolate reductase C terminal K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001659 299.0
HFD3_k127_7481599_13 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000001361 259.0
HFD3_k127_7481599_14 CoA-transferase family III K18702 - 2.8.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000717 255.0
HFD3_k127_7481599_15 Biotin-lipoyl like K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000002832 237.0
HFD3_k127_7481599_16 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000000000000001227 215.0
HFD3_k127_7481599_17 geranylgeranyl reductase - - - 0.0000000000000000000000000000000000000000000000000000000001528 222.0
HFD3_k127_7481599_18 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000001175 201.0
HFD3_k127_7481599_19 GNaT family - - - 0.0000000000000000000000000000000000000000000000217 175.0
HFD3_k127_7481599_2 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 475.0
HFD3_k127_7481599_20 Regulates arginine biosynthesis genes K03402 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000004725 93.0
HFD3_k127_7481599_21 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104,K20201 - 3.1.3.48,3.9.1.2 0.000000000000000004779 97.0
HFD3_k127_7481599_22 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000005628 76.0
HFD3_k127_7481599_23 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000004323 61.0
HFD3_k127_7481599_3 PFAM AMP-dependent synthetase and ligase K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005915 417.0
HFD3_k127_7481599_4 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 375.0
HFD3_k127_7481599_5 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 352.0
HFD3_k127_7481599_6 acr, cog1565 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008529 366.0
HFD3_k127_7481599_7 PFAM short-chain dehydrogenase reductase SDR K00023,K00059 - 1.1.1.100,1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 354.0
HFD3_k127_7481599_8 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 300.0
HFD3_k127_7481599_9 Methionine biosynthesis protein MetW K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006905 308.0
HFD3_k127_7496379_0 Acetamidase formamidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 306.0
HFD3_k127_7496379_1 - - - - 0.0000000000000000000000000000000000004872 143.0
HFD3_k127_7496379_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000614 109.0
HFD3_k127_7496510_0 Periplasmic binding protein domain K01999 - - 4.131e-231 722.0
HFD3_k127_7496510_1 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 566.0
HFD3_k127_7496510_2 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 440.0
HFD3_k127_7496510_3 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008528 434.0
HFD3_k127_7496510_4 Methionine synthase K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 414.0
HFD3_k127_7496510_5 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 375.0
HFD3_k127_7496510_6 ATPases associated with a variety of cellular activities K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009995 311.0
HFD3_k127_7496510_7 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000623 290.0
HFD3_k127_7503041_0 Cache domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 640.0
HFD3_k127_7503041_1 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004911 481.0
HFD3_k127_7503041_2 PFAM response regulator receiver K11443 - - 0.00000000000000000000000000003266 131.0
HFD3_k127_7521562_0 Thiamine pyrophosphate enzyme, central domain - - - 3.625e-205 654.0
HFD3_k127_7521562_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 492.0
HFD3_k127_7521562_10 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000000000000004693 224.0
HFD3_k127_7521562_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000007302 206.0
HFD3_k127_7521562_12 Extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000004072 220.0
HFD3_k127_7521562_13 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000007923 180.0
HFD3_k127_7521562_14 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000396 182.0
HFD3_k127_7521562_15 Protein of unknown function (DUF917) K09703 - - 0.00000000000000000000000000000000000007917 149.0
HFD3_k127_7521562_16 import. Responsible for energy coupling to the transport system K02052 - - 0.000000000000003341 83.0
HFD3_k127_7521562_2 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 416.0
HFD3_k127_7521562_3 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006906 373.0
HFD3_k127_7521562_4 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 373.0
HFD3_k127_7521562_5 capsule polysaccharide biosynthetic process K13687 GO:0008150,GO:0040007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 326.0
HFD3_k127_7521562_6 lytic transglycosylase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 330.0
HFD3_k127_7521562_7 Predicted integral membrane protein (DUF2269) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 287.0
HFD3_k127_7521562_8 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001697 254.0
HFD3_k127_7521562_9 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000008122 229.0
HFD3_k127_7522902_0 enterobactin catabolic process K07214 - - 0.000000000000000000000000000000000000000000000000000000000000000000001606 246.0
HFD3_k127_7522902_1 - - - - 0.000000000000000000000000000004534 124.0
HFD3_k127_7522902_2 - - - - 0.0000000000000000000000000001099 122.0
HFD3_k127_7526476_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 5.358e-209 688.0
HFD3_k127_7526476_1 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004155 545.0
HFD3_k127_7526476_10 Protein involved in cellulose biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007275 307.0
HFD3_k127_7526476_11 Belongs to the enoyl-CoA hydratase isomerase family K08299 - 4.2.1.149 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 299.0
HFD3_k127_7526476_12 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007609 290.0
HFD3_k127_7526476_13 Required for morphogenesis under gluconeogenic growth conditions - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001778 277.0
HFD3_k127_7526476_14 glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005357 291.0
HFD3_k127_7526476_15 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001906 280.0
HFD3_k127_7526476_16 SMART AAA ATPase K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009603 257.0
HFD3_k127_7526476_17 Glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002075 270.0
HFD3_k127_7526476_18 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000001581 258.0
HFD3_k127_7526476_19 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000006753 237.0
HFD3_k127_7526476_2 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 542.0
HFD3_k127_7526476_20 proline dehydrogenase activity K00318 - - 0.000000000000000000000000000000000000000000000000000000004351 222.0
HFD3_k127_7526476_21 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000166 209.0
HFD3_k127_7526476_22 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000217 203.0
HFD3_k127_7526476_23 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000838 213.0
HFD3_k127_7526476_24 Lipopolysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000001546 207.0
HFD3_k127_7526476_25 Protein of unknown function (DUF1698) - - - 0.000000000000000000000000000000000000000000000000001645 207.0
HFD3_k127_7526476_26 Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate K00452 - 1.13.11.6 0.000000000000000000000000000000000000000000000000002152 203.0
HFD3_k127_7526476_27 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000001259 206.0
HFD3_k127_7526476_28 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000135 197.0
HFD3_k127_7526476_29 Stage II sporulation protein E K05518 - 3.1.3.3 0.0000000000000000000000000000000000000000000008322 179.0
HFD3_k127_7526476_3 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 539.0
HFD3_k127_7526476_30 STAS domain K17762 - - 0.0000000000000000000000000000000000000000008816 159.0
HFD3_k127_7526476_31 Protein of unknown function (DUF1566) - - - 0.00000000000000000000000000000000000000001888 175.0
HFD3_k127_7526476_32 Enoyl-CoA hydratase carnithine racemase - - - 0.0000000000000000000000000000000000000000659 172.0
HFD3_k127_7526476_33 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000001856 166.0
HFD3_k127_7526476_34 Polysaccharide biosynthesis/export protein K01991 - - 0.00000000000000000000000000000000000003424 161.0
HFD3_k127_7526476_35 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07675 - 2.7.13.3 0.00000000000000000000000000000000000786 154.0
HFD3_k127_7526476_36 Histidine kinase-like ATPases K17752 - 2.7.11.1 0.00000000000000000000000000000000001509 154.0
HFD3_k127_7526476_37 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000001742 138.0
HFD3_k127_7526476_38 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000008669 126.0
HFD3_k127_7526476_39 Capsular exopolysaccharide family K08252 - 2.7.10.1 0.000000000000000000000000000003666 140.0
HFD3_k127_7526476_4 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00066 - 1.1.1.132 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005848 456.0
HFD3_k127_7526476_40 helix_turn_helix, Lux Regulon K11618 - - 0.00000000000000000000000000002276 123.0
HFD3_k127_7526476_42 Glyoxalase-like domain - - - 0.0000000000000000000006401 101.0
HFD3_k127_7526476_43 O-antigen ligase like membrane protein - - - 0.00000000000000002432 98.0
HFD3_k127_7526476_44 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000007268 82.0
HFD3_k127_7526476_45 ROS/MUCR transcriptional regulator protein - - - 0.000000000006163 71.0
HFD3_k127_7526476_46 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000003118 70.0
HFD3_k127_7526476_48 - - - - 0.000000001351 61.0
HFD3_k127_7526476_49 Protein conserved in bacteria - - - 0.00000002184 66.0
HFD3_k127_7526476_5 Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) K17763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005722 416.0
HFD3_k127_7526476_6 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 368.0
HFD3_k127_7526476_7 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 368.0
HFD3_k127_7526476_8 Heparinase II/III N-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 338.0
HFD3_k127_7526476_9 acyl-CoA dehydrogenase K00252 - 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 308.0
HFD3_k127_7538989_0 radical SAM domain protein K04034 - 1.21.98.3 6.186e-239 748.0
HFD3_k127_7538989_1 Isocitrate/isopropylmalate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 537.0
HFD3_k127_7538989_2 ABC transporter transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 393.0
HFD3_k127_7538989_3 ABC-type sugar transport system, permease component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 311.0
HFD3_k127_7538989_4 Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002686 274.0
HFD3_k127_7538989_5 Extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003999 256.0
HFD3_k127_7549236_0 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008683 502.0
HFD3_k127_7549236_1 acyl-CoA transferases carnitine dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343 450.0
HFD3_k127_7549236_10 Protein tyrosine kinase - - - 0.0004649 52.0
HFD3_k127_7549236_2 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004853 355.0
HFD3_k127_7549236_3 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005653 353.0
HFD3_k127_7549236_4 PAC2 family - - - 0.00000000000000000000000000000000000000000000000001342 191.0
HFD3_k127_7549236_5 EVE domain - - - 0.0000000000000000000000000000000000000000003202 162.0
HFD3_k127_7549236_6 - - - - 0.0000000000000001874 89.0
HFD3_k127_7549236_7 UDP-glucoronosyl and UDP-glucosyl transferase - - - 0.000000000000001477 89.0
HFD3_k127_7549236_8 HPr kinase - - - 0.0000000007808 70.0
HFD3_k127_7549236_9 Uncharacterised nucleotidyltransferase - - - 0.000000008106 68.0
HFD3_k127_7586787_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 1.48e-277 878.0
HFD3_k127_7586787_1 Biotin-lipoyl like K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 314.0
HFD3_k127_7586787_2 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000000000000000000000006005 153.0
HFD3_k127_7586787_3 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000000000000006964 117.0
HFD3_k127_7586787_4 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.00000001079 58.0
HFD3_k127_7637052_0 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005261 431.0
HFD3_k127_7637052_1 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 345.0
HFD3_k127_7637052_2 COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein - - - 0.00000000000000000000000000000000000000000000000000000000000002754 240.0
HFD3_k127_7637052_3 Alanine-glyoxylate amino-transferase K05825 - - 0.0000000000000000000000002371 109.0
HFD3_k127_7637052_4 Redoxin - - - 0.0000004471 51.0
HFD3_k127_7647064_0 Ring hydroxylating alpha subunit (catalytic domain) K08689 - 1.14.12.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004464 537.0
HFD3_k127_7647064_1 C-terminal, D2-small domain, of ClpB protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 443.0
HFD3_k127_7647064_2 Ring hydroxylating beta subunit - - - 0.000000000000000000000000000000000000000000000000005372 203.0
HFD3_k127_7647064_3 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.00000000000000000000000000001231 122.0
HFD3_k127_7647064_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000346 52.0
HFD3_k127_7657969_0 TonB dependent receptor K02014 - - 3.109e-207 669.0
HFD3_k127_7657969_1 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 428.0
HFD3_k127_7657969_2 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 364.0
HFD3_k127_7657969_3 Extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 342.0
HFD3_k127_7657969_4 Binding-protein-dependent transport system inner membrane component K02025,K10237 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008169 277.0
HFD3_k127_7672740_0 4-hydroxyphenylacetate 3-hydroxylase N terminal K00483 - 1.14.14.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 415.0
HFD3_k127_7672740_1 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 389.0
HFD3_k127_7672740_2 ABC-type sugar transport system, permease component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009643 258.0
HFD3_k127_7672740_3 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000001615 250.0
HFD3_k127_7672740_4 Bacterial extracellular solute-binding protein K17329 - - 0.000000000001685 80.0
HFD3_k127_7673233_0 alpha-L-arabinofuranosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 462.0
HFD3_k127_7673233_1 ABC transporter substrate binding protein K01989 - - 0.000000142 59.0
HFD3_k127_786654_0 Bacterial transcriptional repressor C-terminal K16137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006656 253.0
HFD3_k127_786654_1 Fibronectin type 3 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003207 258.0
HFD3_k127_786654_2 - - - - 0.000000000000000000000000000000000000000000000000001357 188.0
HFD3_k127_786654_3 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.000000000000000000000005787 106.0
HFD3_k127_786654_4 Regulator of chromosome condensation (RCC1) repeat - - - 0.00000008592 59.0
HFD3_k127_786654_5 hmm pf04305 - - - 0.00008963 47.0
HFD3_k127_803832_0 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 323.0
HFD3_k127_803832_1 extracellular solute-binding protein, family 5 - - - 0.00000000000000000000000000000000000000000000000000006832 212.0
HFD3_k127_803832_2 lipoprotein biosynthetic process - - - 0.00000000000000000000009113 109.0
HFD3_k127_803832_3 bacterial-type flagellum-dependent cell motility - - - 0.000000001611 63.0
HFD3_k127_830368_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 1.182e-219 719.0
HFD3_k127_830368_1 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009227 378.0
HFD3_k127_830368_2 Amidohydrolase K03392 - 4.1.1.45 0.00000000000000000000000000000000000000000000000000000000000005139 223.0
HFD3_k127_830368_3 serine-type endopeptidase activity K04772,K08372 - - 0.0000000000000000000001226 110.0
HFD3_k127_830368_4 Hydantoinase/oxoprolinase - - - 0.0000000003303 64.0
HFD3_k127_831177_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain - - - 1.797e-209 676.0
HFD3_k127_831177_1 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 520.0
HFD3_k127_831177_10 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006212 299.0
HFD3_k127_831177_11 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 293.0
HFD3_k127_831177_12 PFAM Hydantoinase B oxoprolinase K01469,K01474 - 3.5.2.14,3.5.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 295.0
HFD3_k127_831177_13 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003891 274.0
HFD3_k127_831177_14 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000005054 242.0
HFD3_k127_831177_15 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000006818 218.0
HFD3_k127_831177_16 4-phosphoerythronate dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000001634 220.0
HFD3_k127_831177_17 PFAM SpoU rRNA Methylase family - - - 0.000000000000000000000000000000000000000000000000000000000005924 218.0
HFD3_k127_831177_18 Cupin domain - - - 0.0000000000000000000000000000000000000000000000011 176.0
HFD3_k127_831177_19 Peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000005018 175.0
HFD3_k127_831177_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007232 518.0
HFD3_k127_831177_20 Family of unknown function (DUF1028) - - - 0.0000000000000000000000000000000000000000000008093 176.0
HFD3_k127_831177_21 DinB family - - - 0.0000000000000000000000000000001641 142.0
HFD3_k127_831177_22 EamA-like transporter family - - - 0.0000000000000000000000000000004723 136.0
HFD3_k127_831177_23 membrane transporter protein K07090 - - 0.000000000000000000118 99.0
HFD3_k127_831177_24 Glyoxalase bleomycin resistance protein dioxygenase K07104 - 1.13.11.2 0.000000000000000009523 91.0
HFD3_k127_831177_25 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.0000000000000006394 84.0
HFD3_k127_831177_26 Redoxin K03386 - 1.11.1.15 0.00000000000000112 80.0
HFD3_k127_831177_27 Two component transcriptional regulator, winged helix family K07669,K07672 - - 0.000000000000003225 82.0
HFD3_k127_831177_28 - - - - 0.0000000000005111 80.0
HFD3_k127_831177_29 OmpA family - - - 0.00000000003358 73.0
HFD3_k127_831177_3 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 476.0
HFD3_k127_831177_30 Carboxymuconolactone decarboxylase family - - - 0.0000000001151 65.0
HFD3_k127_831177_31 Thioredoxin - - - 0.00000001979 65.0
HFD3_k127_831177_4 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 444.0
HFD3_k127_831177_5 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004684 370.0
HFD3_k127_831177_6 Phenazine biosynthesis-like protein K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004876 387.0
HFD3_k127_831177_7 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 351.0
HFD3_k127_831177_8 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006606 333.0
HFD3_k127_831177_9 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006803 328.0
HFD3_k127_843326_0 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001484 288.0
HFD3_k127_843326_1 Sporulation related domain - - - 0.0000000000000000000000000005937 123.0
HFD3_k127_843326_2 Sporulation related domain - - - 0.0000000000000003817 92.0
HFD3_k127_849673_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 553.0
HFD3_k127_849673_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00124 - - 0.00001125 51.0
HFD3_k127_851991_0 Periplasmic binding protein domain K01999 - - 4.224e-196 619.0
HFD3_k127_851991_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 514.0
HFD3_k127_851991_10 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000104 259.0
HFD3_k127_851991_11 hexokinase K00844 - 2.7.1.1 0.0000000000000000000000000000000000000000000000000000001806 211.0
HFD3_k127_851991_12 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000007772 211.0
HFD3_k127_851991_13 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000001731 185.0
HFD3_k127_851991_14 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000001122 179.0
HFD3_k127_851991_15 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000001156 156.0
HFD3_k127_851991_16 Isochorismatase family - - - 0.0000000000000000000000004549 113.0
HFD3_k127_851991_17 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000001805 104.0
HFD3_k127_851991_18 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000003578 101.0
HFD3_k127_851991_19 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000005653 90.0
HFD3_k127_851991_2 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008049 465.0
HFD3_k127_851991_20 Cupin - - - 0.000005314 57.0
HFD3_k127_851991_21 Protein of unknown function (DUF1624) - - - 0.0001913 53.0
HFD3_k127_851991_3 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 412.0
HFD3_k127_851991_4 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 364.0
HFD3_k127_851991_5 COGs COG0569 K transport systems NAD-binding component K03499,K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 362.0
HFD3_k127_851991_6 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003778 356.0
HFD3_k127_851991_7 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 331.0
HFD3_k127_851991_8 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 293.0
HFD3_k127_851991_9 PFAM formyl transferase domain protein K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000003024 262.0
HFD3_k127_86445_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168,K07479 GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 7.949e-261 823.0
HFD3_k127_86445_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 610.0
HFD3_k127_86445_2 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 463.0
HFD3_k127_86445_3 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 353.0
HFD3_k127_86445_4 Aminotransferase class-III K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 306.0
HFD3_k127_86445_5 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000007439 267.0
HFD3_k127_86445_6 Phage integrase, N-terminal SAM-like domain K03733,K04763 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001411 264.0
HFD3_k127_86445_7 DNA recombination-mediator protein A K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006125 250.0
HFD3_k127_86445_8 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000006506 234.0
HFD3_k127_86445_9 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000006492 115.0
HFD3_k127_86548_0 Major facilitator Superfamily K08177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 374.0
HFD3_k127_86548_1 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.0000000000000000000000000000000000008557 149.0
HFD3_k127_878179_0 Histidine kinase-like ATPases - - - 6.927e-272 892.0
HFD3_k127_878179_1 Histidine kinase-like ATPases - - - 3.521e-260 865.0
HFD3_k127_878179_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007983 577.0
HFD3_k127_878179_3 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 492.0
HFD3_k127_878179_4 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000005676 183.0
HFD3_k127_878934_0 Pfam:KaiC K08482 - - 6.751e-240 748.0
HFD3_k127_878934_1 Histidine kinase K07683 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005855 475.0
HFD3_k127_878934_2 photoreceptor activity K08481 - - 0.0000000000000000000000000000000000000001488 160.0
HFD3_k127_878934_3 KaiB K08481 - - 0.00000000000000000000000000000000000002155 163.0
HFD3_k127_878934_4 PFAM response regulator receiver ATP-binding region, ATPase-like histidine kinase A-like Hpt PAS fold-3 PAS fold-4 PAS fold - - - 0.0000000000000000000004911 102.0
HFD3_k127_884240_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008219 497.0
HFD3_k127_884240_1 Aminotransferase class-V - GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 435.0
HFD3_k127_884240_10 YGGT family K02221 - - 0.0000000000000000000243 98.0
HFD3_k127_884240_11 DUF167 - - - 0.000000000000006051 78.0
HFD3_k127_884240_12 Belongs to the phosphoglycerate mutase family K02226,K22305 - 3.1.3.3,3.1.3.73 0.0000000001744 63.0
HFD3_k127_884240_13 Essential cell division protein K03589,K06438 - - 0.00003865 49.0
HFD3_k127_884240_2 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009629 442.0
HFD3_k127_884240_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 407.0
HFD3_k127_884240_4 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004676 375.0
HFD3_k127_884240_5 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 291.0
HFD3_k127_884240_6 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000003686 227.0
HFD3_k127_884240_7 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000004863 145.0
HFD3_k127_884240_8 DivIVA protein K04074 - - 0.0000000000000000000001826 103.0
HFD3_k127_884240_9 Tim44 - - - 0.000000000000000000001998 104.0
HFD3_k127_916158_0 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 3.923e-253 798.0
HFD3_k127_916158_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 3.011e-219 693.0
HFD3_k127_916158_10 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 437.0
HFD3_k127_916158_11 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000673 426.0
HFD3_k127_916158_12 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 417.0
HFD3_k127_916158_13 Belongs to the DapA family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007243 410.0
HFD3_k127_916158_14 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004909 410.0
HFD3_k127_916158_15 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008759 401.0
HFD3_k127_916158_16 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 414.0
HFD3_k127_916158_17 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000442 387.0
HFD3_k127_916158_18 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 353.0
HFD3_k127_916158_19 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 325.0
HFD3_k127_916158_2 Belongs to the amidase family K01426 - 3.5.1.4 2.783e-204 667.0
HFD3_k127_916158_20 electron transfer flavoprotein, alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 299.0
HFD3_k127_916158_21 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 307.0
HFD3_k127_916158_22 Alcohol dehydrogenase GroES-like domain K00004 - 1.1.1.303,1.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 297.0
HFD3_k127_916158_23 negative regulation of quinolinate biosynthetic process K03392 GO:0001760,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006140,GO:0006520,GO:0006521,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006769,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009820,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016043,GO:0016053,GO:0016054,GO:0016829,GO:0016830,GO:0016831,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019439,GO:0019752,GO:0022607,GO:0030808,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0033238,GO:0034641,GO:0042402,GO:0042430,GO:0042436,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043648,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046218,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046874,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051174,GO:0051186,GO:0051193,GO:0051196,GO:0051259,GO:0062012,GO:0062014,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0072330,GO:0072524,GO:0072525,GO:0080090,GO:0090357,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902688,GO:1904984,GO:1904985,GO:1905003,GO:1905004,GO:1905012 4.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006257 275.0
HFD3_k127_916158_24 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007724 265.0
HFD3_k127_916158_25 Belongs to the binding-protein-dependent transport system permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006201 260.0
HFD3_k127_916158_26 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004008 264.0
HFD3_k127_916158_27 COG0559 Branched-chain amino acid ABC-type transport system, permease components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004513 253.0
HFD3_k127_916158_28 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000002037 250.0
HFD3_k127_916158_29 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001372 255.0
HFD3_k127_916158_3 Periplasmic binding protein K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 517.0
HFD3_k127_916158_30 Electron transfer flavoprotein domain K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000004566 230.0
HFD3_k127_916158_31 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000254 215.0
HFD3_k127_916158_32 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000006064 206.0
HFD3_k127_916158_33 2OG-Fe(II) oxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000002397 200.0
HFD3_k127_916158_34 PFAM transferase hexapeptide repeat containing protein - - - 0.00000000000000000000000000000000000000000000003555 176.0
HFD3_k127_916158_35 Enoyl-CoA hydratase K16425 GO:0003674,GO:0003824,GO:0004300,GO:0016829,GO:0016835,GO:0016836 - 0.0000000000000000000000000000000000000022 157.0
HFD3_k127_916158_36 Scavenger mRNA decapping enzyme C-term binding - - - 0.00000000000000000000000000000000000001257 148.0
HFD3_k127_916158_37 UbiC transcription regulator-associated domain protein - - - 0.0000000000000000000000000000000004312 141.0
HFD3_k127_916158_38 Prokaryotic N-terminal methylation motif K08084 - - 0.00000182 56.0
HFD3_k127_916158_39 pilus assembly protein PilW K02672 - - 0.000007034 55.0
HFD3_k127_916158_4 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 503.0
HFD3_k127_916158_40 Luciferase-like monooxygenase - - - 0.0001185 49.0
HFD3_k127_916158_5 Belongs to the binding-protein-dependent transport system permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008089 494.0
HFD3_k127_916158_6 Amino-transferase class IV K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 487.0
HFD3_k127_916158_7 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 447.0
HFD3_k127_916158_8 Dehydrogenase K00248,K11410,K18244 GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0019395,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681 1.3.8.1,1.3.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004816 440.0
HFD3_k127_916158_9 acyl-CoA dehydrogenase K00248,K00249 - 1.3.8.1,1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 436.0
HFD3_k127_930915_0 PFAM Carbamoyl-phosphate synthase L chain ATP-binding K01955 - 6.3.5.5 0.0 1405.0
HFD3_k127_930915_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.812e-247 777.0
HFD3_k127_930915_10 Belongs to the ATCase OTCase family K00608,K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 394.0
HFD3_k127_930915_11 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 355.0
HFD3_k127_930915_12 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009549 291.0
HFD3_k127_930915_13 Nucleotidyl transferase K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 294.0
HFD3_k127_930915_14 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001026 284.0
HFD3_k127_930915_15 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001317 286.0
HFD3_k127_930915_16 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000171 275.0
HFD3_k127_930915_17 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003344 263.0
HFD3_k127_930915_18 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000004307 256.0
HFD3_k127_930915_19 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002253 251.0
HFD3_k127_930915_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012,K00066 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.132,1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006702 575.0
HFD3_k127_930915_20 Cytochrome c oxidase subunit III K02276,K02299 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000002713 237.0
HFD3_k127_930915_21 HrcA protein C terminal domain K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000001631 242.0
HFD3_k127_930915_22 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000002404 235.0
HFD3_k127_930915_23 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000005513 237.0
HFD3_k127_930915_24 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000627 228.0
HFD3_k127_930915_25 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000001516 228.0
HFD3_k127_930915_26 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000003853 227.0
HFD3_k127_930915_27 TIGR00255 family - - - 0.00000000000000000000000000000000000000000000000000000000001352 218.0
HFD3_k127_930915_28 Essential for recycling GMP and indirectly, cGMP K00942,K01591 GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8,4.1.1.23 0.000000000000000000000000000000000000000000000000000002117 198.0
HFD3_k127_930915_29 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000000000000000000000005433 209.0
HFD3_k127_930915_3 histidine kinase, HAMP K13598 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008476 560.0
HFD3_k127_930915_30 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000002075 181.0
HFD3_k127_930915_31 orotidine-5'-phosphate decarboxylase activity K01591,K13421 GO:0000003,GO:0000909,GO:0002119,GO:0002164,GO:0003006,GO:0003674,GO:0003824,GO:0004588,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006928,GO:0006996,GO:0007033,GO:0007040,GO:0007275,GO:0007568,GO:0008150,GO:0008152,GO:0008340,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009314,GO:0009405,GO:0009411,GO:0009416,GO:0009628,GO:0009653,GO:0009790,GO:0009791,GO:0009792,GO:0009887,GO:0009987,GO:0010033,GO:0010165,GO:0010212,GO:0010225,GO:0010259,GO:0010332,GO:0014070,GO:0016043,GO:0016477,GO:0016740,GO:0016757,GO:0016763,GO:0016829,GO:0016830,GO:0016831,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0019860,GO:0019953,GO:0022414,GO:0022610,GO:0030447,GO:0030582,GO:0030584,GO:0031012,GO:0032501,GO:0032502,GO:0032504,GO:0034404,GO:0034641,GO:0034654,GO:0035239,GO:0035295,GO:0040007,GO:0040008,GO:0040011,GO:0040014,GO:0040018,GO:0042221,GO:0042455,GO:0042802,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044182,GO:0044205,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0044706,GO:0045927,GO:0046049,GO:0046107,GO:0046108,GO:0046109,GO:0046112,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0048513,GO:0048518,GO:0048546,GO:0048557,GO:0048562,GO:0048565,GO:0048566,GO:0048568,GO:0048598,GO:0048608,GO:0048609,GO:0048638,GO:0048639,GO:0048731,GO:0048856,GO:0048870,GO:0050789,GO:0050793,GO:0050896,GO:0051094,GO:0051179,GO:0051239,GO:0051240,GO:0051674,GO:0051704,GO:0055086,GO:0055123,GO:0060378,GO:0061458,GO:0062039,GO:0062040,GO:0065007,GO:0065008,GO:0071704,GO:0071840,GO:0072527,GO:0072528,GO:0075259,GO:0080171,GO:0090407,GO:0090727,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.10,4.1.1.23 0.000000000000000000000000000000000000000000000004791 188.0
HFD3_k127_930915_32 UbiA prenyltransferase family K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000009724 174.0
HFD3_k127_930915_33 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000008558 173.0
HFD3_k127_930915_34 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0008463,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043021,GO:0043022,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046872,GO:0046914,GO:0071704,GO:1901564 3.5.1.88 0.000000000000000000000000000000000000001327 153.0
HFD3_k127_930915_35 MgtC family K07507 - - 0.00000000000000000000000000000000000009322 156.0
HFD3_k127_930915_36 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000000000000000106 153.0
HFD3_k127_930915_37 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.00000000000000000000000000000000004713 142.0
HFD3_k127_930915_38 protein required for cytochrome oxidase assembly K02259 - - 0.0000000000000000000000000000004938 134.0
HFD3_k127_930915_39 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.0000000000000004233 82.0
HFD3_k127_930915_4 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02481,K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 538.0
HFD3_k127_930915_40 Trm112p-like protein K09791 - - 0.0000000003969 71.0
HFD3_k127_930915_41 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000004257 52.0
HFD3_k127_930915_42 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000009879 56.0
HFD3_k127_930915_43 Domain of unknown function (DUF4390) - - - 0.00003424 53.0
HFD3_k127_930915_44 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.00005518 49.0
HFD3_k127_930915_45 Archease protein family (MTH1598/TM1083) - GO:0000394,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0007275,GO:0007399,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0010720,GO:0010975,GO:0010976,GO:0016070,GO:0022008,GO:0030154,GO:0031344,GO:0031346,GO:0031974,GO:0031981,GO:0032101,GO:0032103,GO:0032501,GO:0032502,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0046483,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0048679,GO:0048680,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050767,GO:0050769,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0051128,GO:0051130,GO:0051239,GO:0051240,GO:0051960,GO:0051962,GO:0060284,GO:0065007,GO:0070013,GO:0070570,GO:0070572,GO:0071704,GO:0072669,GO:0080134,GO:0080135,GO:0090304,GO:0120035,GO:1901360,GO:1903034,GO:1903036,GO:2000026 - 0.0002125 53.0
HFD3_k127_930915_5 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 534.0
HFD3_k127_930915_6 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 491.0
HFD3_k127_930915_7 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 490.0
HFD3_k127_930915_8 DnaJ central domain K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 409.0
HFD3_k127_930915_9 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009867 400.0
HFD3_k127_94067_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 0.0 1103.0
HFD3_k127_94067_1 Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 7.129e-222 694.0
HFD3_k127_94067_10 COGs COG0569 K transport systems NAD-binding component K03499,K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003025 276.0
HFD3_k127_94067_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001035 256.0
HFD3_k127_94067_12 Aldolase/RraA - - - 0.000000000000000000000000000000000000000000000000000000000000000000002764 246.0
HFD3_k127_94067_13 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000008931 196.0
HFD3_k127_94067_14 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000004105 201.0
HFD3_k127_94067_15 ABC-type dipeptide transport system periplasmic component K02035 - - 0.00000000000000000000000000000000000000000000000009167 196.0
HFD3_k127_94067_16 Belongs to the 3-hydroxyisobutyrate dehydrogenase family K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000004306 178.0
HFD3_k127_94067_17 alpha/beta hydrolase fold K01432 - 3.5.1.9 0.00000000000002327 82.0
HFD3_k127_94067_18 outer membrane efflux protein - - - 0.0000000000002529 74.0
HFD3_k127_94067_2 Belongs to the peptidase M12A family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 512.0
HFD3_k127_94067_3 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 521.0
HFD3_k127_94067_4 von Willebrand factor, type A K02448 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009246 520.0
HFD3_k127_94067_5 Beta-lactamase K18372 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 497.0
HFD3_k127_94067_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 385.0
HFD3_k127_94067_7 Associated with various cellular activities K04748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 392.0
HFD3_k127_94067_8 Cytochrome c K02305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 346.0
HFD3_k127_94067_9 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 299.0
HFD3_k127_943229_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner - - - 5e-324 1015.0
HFD3_k127_943229_1 Gamma-glutamyltranspeptidase - - - 2.966e-205 655.0
HFD3_k127_943229_10 Binding-protein-dependent transport system inner membrane component K02033,K15585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008612 294.0
HFD3_k127_943229_11 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001264 281.0
HFD3_k127_943229_12 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000574 261.0
HFD3_k127_943229_13 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034,K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000003921 233.0
HFD3_k127_943229_14 dipeptide transport K02035 - - 0.000000000000000000000000000000000000000000000000000000000000001026 239.0
HFD3_k127_943229_15 ABC-Type Dipeptide Transport System Periplasmic Component K02035,K13889 - - 0.0000000000000000000000000000000000000000000000000000000000002067 235.0
HFD3_k127_943229_16 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000003078 199.0
HFD3_k127_943229_17 belongs to the thioredoxin family K03671,K03672 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.1.8 0.00000000000000000000000000000000000000000000000000223 186.0
HFD3_k127_943229_18 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000002239 210.0
HFD3_k127_943229_19 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000001834 201.0
HFD3_k127_943229_2 xanthine dehydrogenase, a b hammerhead - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 535.0
HFD3_k127_943229_20 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000006752 195.0
HFD3_k127_943229_21 PFAM amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000003319 176.0
HFD3_k127_943229_22 3'-5' exonuclease activity K03547 - - 0.000000000000000000000000000000000000000000001842 174.0
HFD3_k127_943229_23 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000002472 169.0
HFD3_k127_943229_24 FG-GAP repeat protein - - - 0.000000000000000000000000000000000000000002675 176.0
HFD3_k127_943229_25 Transcriptional regulator - - - 0.00000000000000000000000000000000000001341 154.0
HFD3_k127_943229_27 intermembrane phospholipid transfer K07323 - - 0.000000000000000000000004196 117.0
HFD3_k127_943229_28 Hsp20/alpha crystallin family - - - 0.0000000000000000000000116 108.0
HFD3_k127_943229_3 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 472.0
HFD3_k127_943229_30 amine dehydrogenase activity K00355 - 1.6.5.2 0.00000000000000003735 94.0
HFD3_k127_943229_31 DinB family - - - 0.0000000000002655 77.0
HFD3_k127_943229_32 Ferritin-like domain - - - 0.000000001199 70.0
HFD3_k127_943229_4 Benzoate membrane transport protein K05782 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 459.0
HFD3_k127_943229_5 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 428.0
HFD3_k127_943229_6 PFAM Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 405.0
HFD3_k127_943229_7 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 349.0
HFD3_k127_943229_8 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004614 353.0
HFD3_k127_943229_9 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008078 347.0
HFD3_k127_947272_0 PFAM Peptidase family M20 M25 M40 K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000582 348.0
HFD3_k127_947272_1 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 307.0
HFD3_k127_947543_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 1.046e-201 638.0
HFD3_k127_947543_1 PFAM UvrD REP helicase K03657 - 3.6.4.12 2.565e-195 632.0
HFD3_k127_947543_10 TIGRFAM Cell division ATP-binding protein FtsE K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000003893 226.0
HFD3_k127_947543_11 Peptidase family M23 K21471 GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - 0.00000000000000000000000000000000000000000000000000003928 209.0
HFD3_k127_947543_12 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000000000000395 149.0
HFD3_k127_947543_13 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000001075 134.0
HFD3_k127_947543_14 - - - - 0.0000000000002006 85.0
HFD3_k127_947543_15 Belongs to the TPP enzyme family K01576 - 4.1.1.7 0.000004433 51.0
HFD3_k127_947543_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K01876,K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.12,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 596.0
HFD3_k127_947543_3 Two component, sigma54 specific, transcriptional regulator, Fis family K07712,K07714 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 478.0
HFD3_k127_947543_4 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 443.0
HFD3_k127_947543_5 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 378.0
HFD3_k127_947543_6 Pyridoxal-phosphate dependent enzyme K12339 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 316.0
HFD3_k127_947543_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007771 281.0
HFD3_k127_947543_8 PFAM ATP-binding region, ATPase domain protein K02668,K07708,K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000124 272.0
HFD3_k127_947543_9 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000003193 252.0
HFD3_k127_951677_0 carboxylic acid catabolic process K01856,K19802 - 5.1.1.20,5.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000001014 249.0
HFD3_k127_951677_1 Methyltransferase FkbM domain - - - 0.000000000000000000000000000000000000000000000000002189 192.0
HFD3_k127_951677_2 carboxylic ester hydrolase activity K01054 - 3.1.1.23 0.00000000000000000000000000007602 133.0
HFD3_k127_951677_3 Peptidase family M28 K05994 - 3.4.11.10 0.000000000000000003405 94.0
HFD3_k127_951677_4 - - - - 0.00000000005759 74.0
HFD3_k127_953834_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1026.0
HFD3_k127_953834_1 Adenylate and Guanylate cyclase catalytic domain - - - 8.854e-291 949.0
HFD3_k127_953834_10 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 338.0
HFD3_k127_953834_11 NAD(P)-binding Rossmann-like domain K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 340.0
HFD3_k127_953834_12 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 354.0
HFD3_k127_953834_13 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009106 340.0
HFD3_k127_953834_14 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009167 318.0
HFD3_k127_953834_15 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005927 298.0
HFD3_k127_953834_16 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003222 283.0
HFD3_k127_953834_17 CO dehydrogenase flavoprotein domain protein K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000002215 276.0
HFD3_k127_953834_18 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000003297 212.0
HFD3_k127_953834_19 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000002396 208.0
HFD3_k127_953834_2 AMP-binding enzyme K01897 - 6.2.1.3 1.679e-220 713.0
HFD3_k127_953834_20 Serine hydrolase K07002 - - 0.0000000000000000000000000000000000000000000000000000003081 202.0
HFD3_k127_953834_3 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 602.0
HFD3_k127_953834_4 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K19837 - 3.5.1.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 499.0
HFD3_k127_953834_5 formamidase K01455 - 3.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006441 459.0
HFD3_k127_953834_6 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 419.0
HFD3_k127_953834_7 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 376.0
HFD3_k127_953834_8 COG0665 Glycine D-amino acid oxidases (deaminating) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 345.0
HFD3_k127_953834_9 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 362.0