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Overview

ID MAG01689
Name HFD3_bin.31
Sample SMP0045
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Blastocatellia
Order UBA7656
Family UBA7656
Genus JADGNW01
Species
Assembly information
Completeness (%) 97.66
Contamination (%) 0.04
GC content (%) 55.0
N50 (bp) 37,294
Genome size (bp) 5,852,015

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes4289

Gene name Description KEGG GOs EC E-value Score Sequence
HFD3_k127_1017588_0 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 5.806e-270 854.0
HFD3_k127_1017588_1 Domain of unknown function (DUF5117) - - - 1.127e-250 799.0
HFD3_k127_1017588_10 metallophosphoesterase - - - 0.000000000000000000000000000000000000000000000000004353 194.0
HFD3_k127_1017588_11 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000000009408 184.0
HFD3_k127_1017588_12 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000002246 154.0
HFD3_k127_1017588_13 acetyltransferase - - - 0.000000000000000000000000000000133 138.0
HFD3_k127_1017588_14 protein tyrosine phosphatase activity K01104 - 3.1.3.48 0.00000000000000000000511 100.0
HFD3_k127_1017588_15 N-4 methylation of cytosine - - - 0.00000000000000000001647 91.0
HFD3_k127_1017588_2 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 610.0
HFD3_k127_1017588_3 proline dipeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 593.0
HFD3_k127_1017588_4 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 409.0
HFD3_k127_1017588_5 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 389.0
HFD3_k127_1017588_6 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 381.0
HFD3_k127_1017588_7 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 316.0
HFD3_k127_1017588_8 - - - - 0.000000000000000000000000000000000000000000000000000000005248 214.0
HFD3_k127_1017588_9 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000001595 205.0
HFD3_k127_1024325_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 605.0
HFD3_k127_1024325_1 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 443.0
HFD3_k127_1024325_2 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 417.0
HFD3_k127_1024325_3 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009714 343.0
HFD3_k127_1024325_4 oligoendopeptidase F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 330.0
HFD3_k127_1024325_5 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000002213 183.0
HFD3_k127_1024325_6 PFAM Peptidase M16 inactive domain K07263 - - 0.000000000000000000000000000000000373 151.0
HFD3_k127_1024325_7 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000644 98.0
HFD3_k127_1033553_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008553 432.0
HFD3_k127_1033553_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 451.0
HFD3_k127_1033553_2 Putative glutamine amidotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006106 432.0
HFD3_k127_1033553_3 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 290.0
HFD3_k127_1033553_4 Domain of unknown function (DUF4159) - - - 0.0000000000000000000000000000000000000000000000003637 185.0
HFD3_k127_1033553_5 Peptidase C14 caspase catalytic subunit p20 - - - 0.0000000000000000000000000000000000000000000002074 182.0
HFD3_k127_1056698_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0 1050.0
HFD3_k127_1056698_1 Maltogenic Amylase, C-terminal domain K05343 - 3.2.1.1,5.4.99.16 4.252e-268 834.0
HFD3_k127_1056698_10 alpha-L-arabinofuranosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003796 522.0
HFD3_k127_1056698_11 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 482.0
HFD3_k127_1056698_12 C-terminal, D2-small domain, of ClpB protein K03696 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 471.0
HFD3_k127_1056698_13 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 456.0
HFD3_k127_1056698_14 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003621 418.0
HFD3_k127_1056698_15 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007974 411.0
HFD3_k127_1056698_16 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 411.0
HFD3_k127_1056698_17 PFAM aminotransferase, class I K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006035 399.0
HFD3_k127_1056698_18 acyl-CoA transferases carnitine dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007962 381.0
HFD3_k127_1056698_19 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006808 377.0
HFD3_k127_1056698_2 glycosyl transferase family K00697,K16055 - 2.4.1.15,2.4.1.347,3.1.3.12 5.263e-246 780.0
HFD3_k127_1056698_20 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 357.0
HFD3_k127_1056698_21 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004379 355.0
HFD3_k127_1056698_22 SPFH Band 7 PHB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 351.0
HFD3_k127_1056698_23 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 349.0
HFD3_k127_1056698_24 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 300.0
HFD3_k127_1056698_25 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008306 276.0
HFD3_k127_1056698_26 MotA TolQ ExbB proton channel K03561,K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003653 263.0
HFD3_k127_1056698_27 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009406 255.0
HFD3_k127_1056698_28 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000001518 204.0
HFD3_k127_1056698_29 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000113 193.0
HFD3_k127_1056698_3 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 3.009e-218 699.0
HFD3_k127_1056698_30 PFAM Homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000005532 191.0
HFD3_k127_1056698_31 Endoribonuclease L-PSP K09021,K09022 GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0017144,GO:0019740,GO:0019860,GO:0034641,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.99.10 0.000000000000000000000000000000000000000000002251 169.0
HFD3_k127_1056698_32 Conserved hypothetical protein 95 - - - 0.0000000000000000000000000000000000000000002038 166.0
HFD3_k127_1056698_33 methyltransferase activity - - - 0.0000000000000000000000000000000000000001031 155.0
HFD3_k127_1056698_34 PFAM Haloacid dehalogenase domain protein hydrolase - - - 0.00000000000000000000000000000000000001597 153.0
HFD3_k127_1056698_35 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.000000000000000000000000002159 116.0
HFD3_k127_1056698_36 Phosphoglycerate mutase family K03574 - 3.6.1.55 0.000000000000000000000001536 109.0
HFD3_k127_1056698_37 TIGRFAM TonB K03832 - - 0.000000000000000000000004471 112.0
HFD3_k127_1056698_38 PFAM Bacterial regulatory proteins, gntR family K07979 - - 0.00000000000000000000002994 103.0
HFD3_k127_1056698_39 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000003389 100.0
HFD3_k127_1056698_4 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 604.0
HFD3_k127_1056698_40 Preprotein translocase subunit YajC K03210 - - 0.0000000000000000001446 92.0
HFD3_k127_1056698_41 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000000000000007349 86.0
HFD3_k127_1056698_42 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K07533 - 5.2.1.8 0.0000000000000007633 90.0
HFD3_k127_1056698_43 von Willebrand factor, type A - - - 0.000000000000004821 87.0
HFD3_k127_1056698_44 Tetratricopeptide repeat - - - 0.00000000002155 74.0
HFD3_k127_1056698_46 gluconolactonase activity K13276,K13735,K14274 GO:0005575,GO:0005576 - 0.0000002246 61.0
HFD3_k127_1056698_47 PFAM glycosyl transferase family 9 - - - 0.000002939 59.0
HFD3_k127_1056698_48 - - - - 0.00002565 55.0
HFD3_k127_1056698_49 Rhodanese - - - 0.0006156 49.0
HFD3_k127_1056698_5 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008684 590.0
HFD3_k127_1056698_6 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 596.0
HFD3_k127_1056698_7 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 591.0
HFD3_k127_1056698_8 lyase activity K11645 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 560.0
HFD3_k127_1056698_9 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 546.0
HFD3_k127_105686_0 ABC transporter K06020 - 3.6.3.25 1.163e-301 934.0
HFD3_k127_105686_1 PFAM peptidase - - - 9.943e-222 701.0
HFD3_k127_105686_10 Aldehyde dehydrogenase family K22445 - 1.2.99.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000416 415.0
HFD3_k127_105686_11 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 365.0
HFD3_k127_105686_12 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 359.0
HFD3_k127_105686_13 PA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007407 283.0
HFD3_k127_105686_14 Trehalose utilisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004838 269.0
HFD3_k127_105686_15 Alpha-2-Macroglobulin K06894 - - 0.000000000000000000000000000000000000000000000000000000000000008411 229.0
HFD3_k127_105686_16 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.00000000000000000000000000000000000000000000000000000000000002863 220.0
HFD3_k127_105686_17 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000001864 212.0
HFD3_k127_105686_18 Protein of unknown function (DUF1223) - - - 0.00000000000000000000000000000000000000000000000000000003473 207.0
HFD3_k127_105686_19 Stage II sporulation D domain protein K06381 - - 0.0000000000000000000000000000000000000000000000000008039 210.0
HFD3_k127_105686_2 (ABC) transporter K06147,K06148 - - 6.621e-213 678.0
HFD3_k127_105686_20 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000957 189.0
HFD3_k127_105686_21 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.00000000000000000000000000000000000000000005726 162.0
HFD3_k127_105686_22 DinB superfamily - - - 0.0000000000000000000000000000000000000006445 153.0
HFD3_k127_105686_23 Ferredoxin K00529,K04755,K08952,K08953,K08954,K15765 GO:0005575,GO:0005622,GO:0005623,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0046858 1.18.1.3 0.000000000000000000000000000000000000002103 161.0
HFD3_k127_105686_24 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000027 154.0
HFD3_k127_105686_26 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool K06019 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.1 0.0000000000000000000000000007621 123.0
HFD3_k127_105686_27 SpoVT / AbrB like domain K07172 - - 0.00000000000000000000000487 103.0
HFD3_k127_105686_28 SnoaL-like domain - - - 0.0000000000000000008024 93.0
HFD3_k127_105686_29 pilus organization K02674,K07004 - - 0.0000000000001052 81.0
HFD3_k127_105686_3 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 - 1.1.1.42 3.146e-210 664.0
HFD3_k127_105686_30 Leucine rich repeat variant - - - 0.00000000123 66.0
HFD3_k127_105686_4 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 556.0
HFD3_k127_105686_5 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 541.0
HFD3_k127_105686_6 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 456.0
HFD3_k127_105686_7 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004438 436.0
HFD3_k127_105686_8 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 GO:0000302,GO:0001101,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0016672,GO:0016675,GO:0019538,GO:0030091,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0043546,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0048037,GO:0050662,GO:0050896,GO:0055114,GO:0071704,GO:0097159,GO:1901363,GO:1901530,GO:1901564,GO:1901700 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 427.0
HFD3_k127_105686_9 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 426.0
HFD3_k127_108992_0 PFAM NHL repeat - - - 1.008e-196 634.0
HFD3_k127_108992_1 PFAM Aldehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007445 596.0
HFD3_k127_108992_10 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001177 285.0
HFD3_k127_108992_11 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway K08967 - 1.13.11.53,1.13.11.54 0.0000000000000000000000000000000000000000000000000000000000000000000000001563 255.0
HFD3_k127_108992_12 Probable molybdopterin binding domain K03742 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000008905 235.0
HFD3_k127_108992_13 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000001714 228.0
HFD3_k127_108992_14 RadC-like JAB domain K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000003421 227.0
HFD3_k127_108992_15 Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene) K09880 - 3.1.3.77 0.00000000000000000000000000000000000000000000000000000000000008632 224.0
HFD3_k127_108992_16 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) K08964 - 4.2.1.109 0.0000000000000000000000000000000000000000000000000000000007536 209.0
HFD3_k127_108992_17 Putative Ig domain - - - 0.00000000000000000000000000000000000000000000000000000005312 224.0
HFD3_k127_108992_18 AntiSigma factor - - - 0.000000000000000000000000000000000000000009204 166.0
HFD3_k127_108992_19 PFAM pyridoxamine 5'-phosphate oxidase-related - - - 0.0000000000000000000000000000000000005549 145.0
HFD3_k127_108992_2 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008527 595.0
HFD3_k127_108992_20 DoxX-like family - - - 0.000000000000000000000000000000001083 134.0
HFD3_k127_108992_21 - - - - 0.000000000000000000000004287 107.0
HFD3_k127_108992_22 - - - - 0.000000000001077 74.0
HFD3_k127_108992_23 PFAM Plasmid pRiA4b ORF-3-like protein - - - 0.00000000002419 71.0
HFD3_k127_108992_24 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000001707 74.0
HFD3_k127_108992_25 pyridoxamine 5-phosphate K07005 - - 0.000000002364 64.0
HFD3_k127_108992_26 - - - - 0.00000001839 64.0
HFD3_k127_108992_27 4-amino-4-deoxy-L-arabinose transferase activity K02277 - 1.9.3.1 0.00000001969 67.0
HFD3_k127_108992_3 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000462 430.0
HFD3_k127_108992_4 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005018 420.0
HFD3_k127_108992_5 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11779,K11784 - 1.21.98.1,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 401.0
HFD3_k127_108992_6 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 398.0
HFD3_k127_108992_7 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 301.0
HFD3_k127_108992_8 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004123 301.0
HFD3_k127_108992_9 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003941 287.0
HFD3_k127_1105617_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 0.0 1039.0
HFD3_k127_1105617_1 beta' subunit K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004836 283.0
HFD3_k127_1105617_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008053 276.0
HFD3_k127_1105617_3 PFAM NADH flavin oxidoreductase NADH oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000003184 232.0
HFD3_k127_1105617_4 protein possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000000000000000000000208 171.0
HFD3_k127_1105617_5 - - - - 0.000000000000000000000000000000000000001046 153.0
HFD3_k127_1105617_6 Tetratricopeptide repeat - - - 0.0000000000000000000000002321 120.0
HFD3_k127_1105617_7 His Kinase A (phosphoacceptor) domain K03320 - - 0.00000000000000000003619 95.0
HFD3_k127_1105617_8 photosystem II stabilization - - - 0.000000000000001142 90.0
HFD3_k127_1112664_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2012.0
HFD3_k127_1112664_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2010.0
HFD3_k127_1112664_10 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000008075 88.0
HFD3_k127_1112664_11 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000016 82.0
HFD3_k127_1112664_12 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0002688 48.0
HFD3_k127_1112664_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 2.689e-287 897.0
HFD3_k127_1112664_3 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 306.0
HFD3_k127_1112664_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000006444 231.0
HFD3_k127_1112664_5 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000006895 220.0
HFD3_k127_1112664_6 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000202 219.0
HFD3_k127_1112664_7 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000003978 214.0
HFD3_k127_1112664_8 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000009238 139.0
HFD3_k127_1112664_9 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000004276 137.0
HFD3_k127_1136882_0 ATPase activity K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007529 378.0
HFD3_k127_1136882_1 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008238 340.0
HFD3_k127_1136882_2 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009204 282.0
HFD3_k127_1136882_3 Y_Y_Y domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000257 286.0
HFD3_k127_1136882_4 BMC K04025 - - 0.00000000000000000000000000000000000007494 151.0
HFD3_k127_1175183_0 PFAM Conserved region in glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1500.0
HFD3_k127_1175183_1 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 0.0 1107.0
HFD3_k127_1175183_10 DinB family - - - 0.00000000000000000000000000000000000000000000000000001042 198.0
HFD3_k127_1175183_11 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000001007 156.0
HFD3_k127_1175183_12 Calcium/calmodulin dependent protein kinase II association domain - - - 0.00000000000000000000000000000000006952 139.0
HFD3_k127_1175183_2 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 2.419e-240 757.0
HFD3_k127_1175183_3 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 1.334e-225 709.0
HFD3_k127_1175183_4 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 6.271e-214 674.0
HFD3_k127_1175183_5 Ammonium Transporter K03320 - - 1.776e-194 617.0
HFD3_k127_1175183_6 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 495.0
HFD3_k127_1175183_7 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007271 476.0
HFD3_k127_1175183_8 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 478.0
HFD3_k127_1175183_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005091 254.0
HFD3_k127_1212704_0 choline dehydrogenase activity - - - 8.067e-241 755.0
HFD3_k127_1212704_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000041 289.0
HFD3_k127_1212704_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000233 190.0
HFD3_k127_1212704_3 Gluconate 2-dehydrogenase subunit 3 K06152 - 1.1.99.3 0.00000000000000000000000000000000000000000004662 166.0
HFD3_k127_1212704_4 Domain of unknown function (DUF4252) - - - 0.0000000000000000000000000000000005794 139.0
HFD3_k127_1212704_5 - - - - 0.00000000000000000000000001051 111.0
HFD3_k127_1212704_6 Tetratricopeptide repeat K12132 - 2.7.11.1 0.00002848 47.0
HFD3_k127_1212704_7 - - - - 0.00007181 52.0
HFD3_k127_1255897_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1017.0
HFD3_k127_1255897_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 3.15e-198 646.0
HFD3_k127_1255897_2 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009262 632.0
HFD3_k127_1255897_3 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000682 503.0
HFD3_k127_1255897_4 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240,K00245 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 374.0
HFD3_k127_1255897_5 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01751,K01754,K06016,K17989 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008838,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.6,3.5.1.87,4.3.1.15,4.3.1.17,4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 338.0
HFD3_k127_1255897_6 Beta-lactamase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000046 273.0
HFD3_k127_1255897_7 Zn peptidase - - - 0.000000000000000000000000000000000000000000000000000000003485 217.0
HFD3_k127_1255897_8 succinate dehydrogenase K00241,K00247 - - 0.00000000000000000000000000000000000000000000000000008246 196.0
HFD3_k127_1255897_9 Beta-lactamase - - - 0.0001684 50.0
HFD3_k127_1315924_0 Serine/Threonine protein kinases, catalytic domain K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.0000000000000000000000000000000000000001225 171.0
HFD3_k127_1315924_2 Pfam:Arch_ATPase K02450 - - 0.0000001912 53.0
HFD3_k127_1336_0 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667 - 4.1.99.1 1.186e-220 693.0
HFD3_k127_1336_1 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 1.933e-215 686.0
HFD3_k127_1336_10 - - - - 0.00000000000000000000000000000000000000000000000000000000001073 226.0
HFD3_k127_1336_11 DoxX - - - 0.0000000000000000000000000000000000000002957 153.0
HFD3_k127_1336_12 OsmC-like protein - - - 0.000000000000000000000000000000000002872 145.0
HFD3_k127_1336_13 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000002291 136.0
HFD3_k127_1336_14 PFAM Major Facilitator Superfamily K08196,K08369 - - 0.0000000000000000000000000005056 115.0
HFD3_k127_1336_15 Phosphorylase superfamily K01243 - 3.2.2.9 0.000000000000002613 85.0
HFD3_k127_1336_16 -Thioesterase K01075 - 3.1.2.23 0.000000000006934 72.0
HFD3_k127_1336_2 NADH oxidase - - - 3.998e-208 657.0
HFD3_k127_1336_3 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000968 431.0
HFD3_k127_1336_4 PFAM Transketolase central region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 430.0
HFD3_k127_1336_5 ADP-glyceromanno-heptose 6-epimerase activity K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008393 398.0
HFD3_k127_1336_6 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K00945,K02945,K03527 - 1.17.7.4,2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 379.0
HFD3_k127_1336_7 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009179 378.0
HFD3_k127_1336_8 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K09461 - 1.14.13.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 378.0
HFD3_k127_1336_9 Dehydrogenase E1 component K00161,K00166,K11381,K21416 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000008231 247.0
HFD3_k127_1396957_0 Hydrolase CocE NonD family - - - 0.0 1010.0
HFD3_k127_1396957_1 Putative diguanylate phosphodiesterase - - - 1.28e-208 672.0
HFD3_k127_1396957_10 Mo-co oxidoreductase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 342.0
HFD3_k127_1396957_11 Quinolinate phosphoribosyl transferase, N-terminal domain K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 309.0
HFD3_k127_1396957_12 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 309.0
HFD3_k127_1396957_13 DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002885 260.0
HFD3_k127_1396957_14 NUDIX domain K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000392 210.0
HFD3_k127_1396957_15 cytochrome - - - 0.0000000000000000000000000000000000000000000004334 171.0
HFD3_k127_1396957_16 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000000000000000000000005464 159.0
HFD3_k127_1396957_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 546.0
HFD3_k127_1396957_3 PFAM CobN Magnesium Chelatase K02230,K03403 - 6.6.1.1,6.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 529.0
HFD3_k127_1396957_4 5'-3' exonuclease, N-terminal resolvase-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 462.0
HFD3_k127_1396957_5 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008512 474.0
HFD3_k127_1396957_6 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 469.0
HFD3_k127_1396957_7 magnesium chelatase K03404,K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005143 434.0
HFD3_k127_1396957_8 introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX K03404 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 435.0
HFD3_k127_1396957_9 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006231 380.0
HFD3_k127_1398566_0 COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000001433 221.0
HFD3_k127_1398566_1 TraM recognition site of TraD and TraG K03205 - - 0.00000000000002793 87.0
HFD3_k127_1398566_3 TIGRFAM RHS repeat-associated core - - - 0.00004346 57.0
HFD3_k127_1398566_4 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - 0.000729 44.0
HFD3_k127_144084_0 Zinc-binding dehydrogenase K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004877 471.0
HFD3_k127_144084_1 PDZ domain (Also known as DHR or GLGF) K08372 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006649 417.0
HFD3_k127_144084_2 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 404.0
HFD3_k127_144084_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008959 380.0
HFD3_k127_144084_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000002646 187.0
HFD3_k127_144084_5 PFAM HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000000005115 151.0
HFD3_k127_1458004_0 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000006302 263.0
HFD3_k127_1458004_1 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000001755 117.0
HFD3_k127_1483053_0 Gaf domain K01768,K11527,K18967,K21009 - 2.7.13.3,2.7.7.65,4.6.1.1 0.00000000000000000000000000000000000000000000000002031 206.0
HFD3_k127_1483053_1 MacB-like periplasmic core domain - - - 0.000000000608 61.0
HFD3_k127_1559556_0 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - 0.0 1281.0
HFD3_k127_1559556_1 L-lactate permease K03303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 571.0
HFD3_k127_1559556_2 Cysteine dioxygenase type I K00456 - 1.13.11.20 0.000000000000000000000000000000000000000000000000002085 190.0
HFD3_k127_1559556_3 methyltransferase activity - - - 0.000000000000000000000000000000001183 138.0
HFD3_k127_1559556_4 spectrin binding - - - 0.000000000000000000000000001389 122.0
HFD3_k127_1559556_6 Cytochrome c K00406,K08906 - - 0.0000000001271 67.0
HFD3_k127_1559556_7 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00000776 55.0
HFD3_k127_1560984_0 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 567.0
HFD3_k127_1560984_1 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11779,K11784 - 1.21.98.1,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 367.0
HFD3_k127_1560984_2 histone H2A K63-linked ubiquitination K00998,K06131 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002978 286.0
HFD3_k127_1560984_3 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.000000000000000000000000000000000000000000000007217 177.0
HFD3_k127_1560984_5 COGs COG0596 hydrolase or acyltransferase (alpha beta hydrolase superfamily) - - - 0.000000000000000006731 94.0
HFD3_k127_1560984_6 Protein of unknown function (DUF2752) - - - 0.0000000003376 68.0
HFD3_k127_1560984_7 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.00000001556 55.0
HFD3_k127_1560984_8 Recombinase zinc beta ribbon domain - - - 0.000131 49.0
HFD3_k127_1572799_0 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 509.0
HFD3_k127_1572799_1 Domain of unknown function (DUF4139) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 475.0
HFD3_k127_1572799_2 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 301.0
HFD3_k127_1572799_3 sister chromatid segregation - - - 0.000000000000000000000000000000000002646 155.0
HFD3_k127_1573612_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 4.394e-196 623.0
HFD3_k127_1573612_1 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 516.0
HFD3_k127_1573612_2 Cell shape determining protein MreB Mrl K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 322.0
HFD3_k127_1573612_3 N-Acetylmuramoyl-L-alanine amidase K11066,K12287 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000001697 212.0
HFD3_k127_1573612_4 PFAM peptidase K16922 - - 0.0000000000000000000000000000000000000000000000000000008377 219.0
HFD3_k127_1573612_5 Evidence 4 Homologs of previously reported genes of K09700 - - 0.00000000000000000000000000000003388 128.0
HFD3_k127_1573612_6 PilZ domain K02676 - - 0.0000004804 57.0
HFD3_k127_1573612_7 - - - - 0.000000499 52.0
HFD3_k127_1573612_8 Sporulation related domain - - - 0.000007929 58.0
HFD3_k127_158677_0 FtsX-like permease family - - - 9.248e-251 799.0
HFD3_k127_158677_1 Belongs to the enoyl-CoA hydratase isomerase family K07516 - 1.1.1.35 2.295e-235 748.0
HFD3_k127_158677_10 - - - - 0.0000000000000000000000000000000000000002397 165.0
HFD3_k127_158677_11 Transposase IS200 like K07491 - - 0.0000000000000000000000000000000004276 137.0
HFD3_k127_158677_12 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000001985 119.0
HFD3_k127_158677_14 - - - - 0.0000000000000000000003506 101.0
HFD3_k127_158677_15 Rhodanese Homology Domain - - - 0.000000000000000000001686 99.0
HFD3_k127_158677_16 - - - - 0.000000000000000000009283 93.0
HFD3_k127_158677_17 COG3678 P pilus assembly Cpx signaling pathway, periplasmic inhibitor zinc-resistance associated protein K06006 - - 0.00001374 53.0
HFD3_k127_158677_18 - - - - 0.00002999 51.0
HFD3_k127_158677_2 FtsX-like permease family - - - 6.738e-221 713.0
HFD3_k127_158677_3 efflux transmembrane transporter activity K02004 - - 1.109e-212 687.0
HFD3_k127_158677_4 MacB-like periplasmic core domain - - - 2.738e-210 680.0
HFD3_k127_158677_5 WD40 repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 565.0
HFD3_k127_158677_6 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 460.0
HFD3_k127_158677_7 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008934 398.0
HFD3_k127_158677_8 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005555 332.0
HFD3_k127_158677_9 protein conserved in bacteria K09990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006363 287.0
HFD3_k127_1596947_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1253.0
HFD3_k127_1596947_1 metallocarboxypeptidase activity K14054 - - 0.0 1229.0
HFD3_k127_1596947_10 Domain of Unknown Function (DUF1259) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 309.0
HFD3_k127_1596947_11 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006802 301.0
HFD3_k127_1596947_12 Exodeoxyribonuclease iii K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 291.0
HFD3_k127_1596947_13 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.00000000000000000000000000000000000000000000000000000000000000000001166 250.0
HFD3_k127_1596947_14 fatty acid transporter K02106 - - 0.0000000000000000000000000000000000000000000000000000000004143 220.0
HFD3_k127_1596947_15 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000001454 207.0
HFD3_k127_1596947_16 Pyruvate phosphate dikinase - - - 0.00000000000000000000000000000000000000000000000000002667 197.0
HFD3_k127_1596947_17 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000002318 183.0
HFD3_k127_1596947_18 - - - - 0.000000000000000000000000000000000000000000000001999 181.0
HFD3_k127_1596947_19 - - - - 0.00000000000000000000000000000000000000000000003105 178.0
HFD3_k127_1596947_2 metallocarboxypeptidase activity K14054 - - 9.407e-283 900.0
HFD3_k127_1596947_20 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000002554 144.0
HFD3_k127_1596947_21 - - - - 0.0000000000000000000000000000000000004175 152.0
HFD3_k127_1596947_22 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000002071 113.0
HFD3_k127_1596947_23 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07239,K15726 - - 0.0000000000000000000000004747 108.0
HFD3_k127_1596947_24 - - - - 0.0000000000000000000002997 101.0
HFD3_k127_1596947_25 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000001502 99.0
HFD3_k127_1596947_26 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000007817 93.0
HFD3_k127_1596947_27 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000002317 70.0
HFD3_k127_1596947_28 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000041 67.0
HFD3_k127_1596947_29 ACT domain - - - 0.0000000004591 67.0
HFD3_k127_1596947_3 PQQ-like domain K05889 - 1.1.2.6 3.308e-252 792.0
HFD3_k127_1596947_30 Periplasmic copper-binding protein (NosD) - - - 0.000000003305 68.0
HFD3_k127_1596947_31 - - - - 0.0000000114 68.0
HFD3_k127_1596947_33 Peptidase dimerisation domain K12941 - - 0.0005102 43.0
HFD3_k127_1596947_4 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000839 568.0
HFD3_k127_1596947_5 Putative methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 511.0
HFD3_k127_1596947_6 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 454.0
HFD3_k127_1596947_7 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.3.1.29,2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 456.0
HFD3_k127_1596947_8 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005515 413.0
HFD3_k127_1596947_9 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0090304,GO:0097056,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008626 415.0
HFD3_k127_1643075_0 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 1.182e-301 940.0
HFD3_k127_1643075_1 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 2.625e-261 832.0
HFD3_k127_1643075_10 DUF35 OB-fold domain, acyl-CoA-associated K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007511 405.0
HFD3_k127_1643075_11 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 370.0
HFD3_k127_1643075_12 GlcNAc-PI de-N-acetylase K01463 - - 0.000000000000000000000000000000000000000000000000000000001883 208.0
HFD3_k127_1643075_13 dehydratase - - - 0.000000000000000000000000000000000000000000000001104 179.0
HFD3_k127_1643075_14 TspO/MBR family - - - 0.00000000000000000000000000000000000000000000001165 175.0
HFD3_k127_1643075_15 - - - - 0.0000000000000000000000000000000000000000000006957 170.0
HFD3_k127_1643075_16 dehydratase - - - 0.00000000000000000000000000000000000000000001539 172.0
HFD3_k127_1643075_17 flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase - - - 0.000000000000000000000000000000000000000001342 161.0
HFD3_k127_1643075_18 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000001047 124.0
HFD3_k127_1643075_19 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000003444 126.0
HFD3_k127_1643075_2 Peptidase S46 - - - 2.1e-233 745.0
HFD3_k127_1643075_20 F420H(2)-dependent quinone reductase - - - 0.00000000000006359 76.0
HFD3_k127_1643075_21 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000815 79.0
HFD3_k127_1643075_3 PFAM NAD-dependent epimerase dehydratase - - - 1.427e-203 644.0
HFD3_k127_1643075_4 PFAM gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 549.0
HFD3_k127_1643075_5 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 496.0
HFD3_k127_1643075_6 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005634 466.0
HFD3_k127_1643075_7 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 424.0
HFD3_k127_1643075_8 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007813 424.0
HFD3_k127_1643075_9 glycosyl transferase group 1 K00754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007555 418.0
HFD3_k127_165867_0 iron-nicotianamine transmembrane transporter activity - - - 7.106e-287 904.0
HFD3_k127_165867_1 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666 - - 3.6e-225 710.0
HFD3_k127_165867_10 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007269 279.0
HFD3_k127_165867_11 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001141 283.0
HFD3_k127_165867_12 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000007441 255.0
HFD3_k127_165867_13 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000001969 248.0
HFD3_k127_165867_14 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000335 221.0
HFD3_k127_165867_15 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000000003129 169.0
HFD3_k127_165867_16 TIGRFAM Outer membrane assembly lipoprotein YfiO K05807 - - 0.0000000000000000000000000000000007692 145.0
HFD3_k127_165867_17 Reeler domain - - - 0.00000000000000003006 94.0
HFD3_k127_165867_18 Transcription factor zinc-finger K09981 - - 0.00000000009707 66.0
HFD3_k127_165867_19 - - - - 0.00000004991 64.0
HFD3_k127_165867_2 ABC transporter K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 575.0
HFD3_k127_165867_20 PFAM Protein kinase domain K12132 - 2.7.11.1 0.0000417 51.0
HFD3_k127_165867_3 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 434.0
HFD3_k127_165867_4 signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009266 425.0
HFD3_k127_165867_5 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 411.0
HFD3_k127_165867_6 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 312.0
HFD3_k127_165867_7 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 310.0
HFD3_k127_165867_8 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 301.0
HFD3_k127_165867_9 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003869 306.0
HFD3_k127_1674295_0 radical SAM domain protein - - - 6.402e-240 749.0
HFD3_k127_1674295_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008059 617.0
HFD3_k127_1674295_10 phosphoenolpyruvate carboxykinase (ATP) activity K01610 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019318,GO:0019319,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 4.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 314.0
HFD3_k127_1674295_11 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004172 321.0
HFD3_k127_1674295_12 pfkB family carbohydrate kinase K18478 - 2.7.1.184 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 294.0
HFD3_k127_1674295_13 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 303.0
HFD3_k127_1674295_14 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003926 301.0
HFD3_k127_1674295_15 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001634 273.0
HFD3_k127_1674295_16 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003105 275.0
HFD3_k127_1674295_17 PFAM Xylose isomerase-like TIM barrel K03335 - 4.2.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000007104 259.0
HFD3_k127_1674295_18 Formyl transferase K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000003787 244.0
HFD3_k127_1674295_19 Domain of unknown function (DUF4287) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001701 241.0
HFD3_k127_1674295_2 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 617.0
HFD3_k127_1674295_20 Transcriptional regulator, LysR - - - 0.000000000000000000000000000000000000000000000000000000000000000001013 246.0
HFD3_k127_1674295_21 Subtilase family K14645 GO:0005575,GO:0005576 - 0.000000000000000000000000000000000000000000000000000000000000000005047 247.0
HFD3_k127_1674295_22 PQQ enzyme repeat K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000001927 244.0
HFD3_k127_1674295_23 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000001971 203.0
HFD3_k127_1674295_24 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000000003066 192.0
HFD3_k127_1674295_25 protein tyrosine phosphatase activity K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000000000562 178.0
HFD3_k127_1674295_26 PFAM peptidylprolyl isomerase FKBP-type K01802 - 5.2.1.8 0.000000000000000000000000000000000000000001315 160.0
HFD3_k127_1674295_27 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000007103 166.0
HFD3_k127_1674295_28 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000000000000000000000006937 140.0
HFD3_k127_1674295_29 von Willebrand factor, type A - - - 0.0000000000000000000000000000000005266 145.0
HFD3_k127_1674295_3 TIGRFAM glutamine synthetase, type I K01915 GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 595.0
HFD3_k127_1674295_31 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000001974 134.0
HFD3_k127_1674295_32 dTDP biosynthetic process K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000001787 134.0
HFD3_k127_1674295_33 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000004676 140.0
HFD3_k127_1674295_34 Belongs to the ompA family - - - 0.0000000000000000000000001796 115.0
HFD3_k127_1674295_35 phosphoserine phosphatase activity K04757 - 2.7.11.1 0.00000000000000000000003391 103.0
HFD3_k127_1674295_36 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000002985 110.0
HFD3_k127_1674295_37 PFAM Cyclic nucleotide-binding - - - 0.000000000000000000002475 95.0
HFD3_k127_1674295_38 PFAM Cyclic nucleotide-binding - - - 0.000000000000000000008401 96.0
HFD3_k127_1674295_4 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 497.0
HFD3_k127_1674295_40 Response regulator, receiver K06147 - - 0.00000000000000008444 86.0
HFD3_k127_1674295_41 PFAM Forkhead-associated protein - - - 0.0000000000000118 83.0
HFD3_k127_1674295_42 Periplasmic binding protein-like domain - - - 0.00000000000003623 74.0
HFD3_k127_1674295_43 Periplasmic or secreted lipoprotein - - - 0.0000000000001309 80.0
HFD3_k127_1674295_44 TIGRFAM TonB family C-terminal domain K03832 - - 0.0000000000005929 78.0
HFD3_k127_1674295_45 Matrixin - - - 0.000000000002589 80.0
HFD3_k127_1674295_46 Cyclic nucleotide-monophosphate binding domain - - - 0.00000006724 56.0
HFD3_k127_1674295_47 Belongs to the 5'-nucleotidase family - - - 0.0000001063 63.0
HFD3_k127_1674295_48 - K03686 - - 0.0000003441 56.0
HFD3_k127_1674295_49 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.00002594 57.0
HFD3_k127_1674295_5 sequence-specific DNA binding K07110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 425.0
HFD3_k127_1674295_50 TPR repeat-containing protein K07452 - - 0.00004676 55.0
HFD3_k127_1674295_6 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008792 394.0
HFD3_k127_1674295_7 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 347.0
HFD3_k127_1674295_8 ornithine cyclodeaminase activity K01750,K19244 - 1.4.1.1,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009136 345.0
HFD3_k127_1674295_9 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009857 330.0
HFD3_k127_1690179_0 Sodium calcium exchanger membrane K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 410.0
HFD3_k127_1690179_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000004404 230.0
HFD3_k127_1690179_2 Protein of unknown function (DUF2950) - - - 0.0000000000000000001044 89.0
HFD3_k127_1690179_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000003041 99.0
HFD3_k127_1690179_4 Protein of unknown function (DUF3616) - - - 0.000000000000006116 88.0
HFD3_k127_1690179_5 Serine dehydratase K01752 - 4.3.1.17 0.0001341 45.0
HFD3_k127_171940_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 618.0
HFD3_k127_171940_1 reverse transcriptase K00986 - 2.7.7.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 589.0
HFD3_k127_171940_10 CAAX protease self-immunity K07052 - - 0.00000000000000000000001368 109.0
HFD3_k127_171940_11 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.00000000002354 65.0
HFD3_k127_171940_12 Protein of unknown function (DUF2911) - - - 0.00000000006855 69.0
HFD3_k127_171940_13 COG3307 Lipid A core - O-antigen ligase and related enzymes - - - 0.0000000002888 73.0
HFD3_k127_171940_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 498.0
HFD3_k127_171940_3 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 436.0
HFD3_k127_171940_4 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 417.0
HFD3_k127_171940_5 Heparinase II/III-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 343.0
HFD3_k127_171940_6 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006856 278.0
HFD3_k127_171940_7 Glycosyl transferase family 2 K16870 - 2.4.1.289 0.00000000000000000000000000000000000000000000000000000000000000000009567 245.0
HFD3_k127_171940_8 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000003966 218.0
HFD3_k127_1755245_0 Carboxypeptidase regulatory-like domain - - - 0.0 1264.0
HFD3_k127_1755245_1 PFAM Prolyl oligopeptidase family - - - 1.046e-290 904.0
HFD3_k127_1755245_10 Molybdenum Cofactor Synthesis C K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 346.0
HFD3_k127_1755245_11 PFAM YdjC family protein K03478 - 3.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003934 302.0
HFD3_k127_1755245_12 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000204 279.0
HFD3_k127_1755245_13 - - - - 0.000000000000000000000000000000000000000000000000004522 188.0
HFD3_k127_1755245_14 PFAM pyridoxamine 5'-phosphate oxidase-related, FMN-binding K07006 - - 0.00000000000000000000000000001092 121.0
HFD3_k127_1755245_15 - - - - 0.000000000000003003 78.0
HFD3_k127_1755245_2 hydrolase, family 3 K05349 - 3.2.1.21 1.216e-279 879.0
HFD3_k127_1755245_3 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 1.252e-273 854.0
HFD3_k127_1755245_4 Sodium:solute symporter family K03307 - - 3.084e-260 812.0
HFD3_k127_1755245_5 Prolyl oligopeptidase family - - - 2.91e-241 767.0
HFD3_k127_1755245_6 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 4.453e-200 629.0
HFD3_k127_1755245_7 Cys/Met metabolism PLP-dependent enzyme K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007283 569.0
HFD3_k127_1755245_8 Galactokinase galactose-binding signature K00849 - 2.7.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 431.0
HFD3_k127_1755245_9 Putative glucoamylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 430.0
HFD3_k127_1786674_0 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005322 498.0
HFD3_k127_1786674_1 Zinc-binding dehydrogenase K17818 - 1.1.1.287 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 377.0
HFD3_k127_1786674_2 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 346.0
HFD3_k127_1786674_3 Periplasmic binding protein-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001123 249.0
HFD3_k127_1786674_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007413 255.0
HFD3_k127_1786674_5 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000002754 251.0
HFD3_k127_1786674_6 COG3622 Hydroxypyruvate isomerase K01816 - 5.3.1.22 0.000000000000000000000000000000000000000000000000000003064 200.0
HFD3_k127_1787021_0 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006454 465.0
HFD3_k127_1787021_1 sequence-specific DNA binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 436.0
HFD3_k127_1787021_2 methyltransferase activity K21310 - 2.1.1.334 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 323.0
HFD3_k127_1787021_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000007668 230.0
HFD3_k127_1787021_4 ASCH - - - 0.0000000000000000000000000000000001694 134.0
HFD3_k127_1787021_5 Protein of unknown function (DUF454) K09790 - - 0.00000000000002046 82.0
HFD3_k127_1787021_6 PNKP adenylyltransferase domain, ligase domain - - - 0.00000000003861 64.0
HFD3_k127_1787021_7 cAMP biosynthetic process - - - 0.00002698 52.0
HFD3_k127_179707_0 Carboxypeptidase regulatory-like domain - - - 0.0 1237.0
HFD3_k127_179707_1 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 592.0
HFD3_k127_179707_2 TIGRFAM galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004406 485.0
HFD3_k127_179707_3 PFAM amidohydrolase - - - 0.0000001493 54.0
HFD3_k127_179707_4 PFAM amidohydrolase - - - 0.000003036 50.0
HFD3_k127_1811768_0 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 452.0
HFD3_k127_1811768_1 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 369.0
HFD3_k127_1811768_2 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001132 286.0
HFD3_k127_1811768_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003085 256.0
HFD3_k127_1811768_4 WD40 repeats - - - 0.000000000000000000000000000000000000000000000000000000003278 214.0
HFD3_k127_1811768_5 Protein of unknown function (DUF2950) - - - 0.000000001742 62.0
HFD3_k127_1811787_0 Amino acid adenylation domain - - - 0.0 1440.0
HFD3_k127_1811787_1 PBS lyase HEAT-like repeat - - - 9.401e-318 997.0
HFD3_k127_1811787_10 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003257 272.0
HFD3_k127_1811787_11 CheC inhibitor of MCP methylation K03410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000522 251.0
HFD3_k127_1811787_12 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000000000000000000002561 188.0
HFD3_k127_1811787_13 Response regulator receiver domain K03413 - - 0.000000000000000000000000000000000000000001983 159.0
HFD3_k127_1811787_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 2.142e-223 712.0
HFD3_k127_1811787_3 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 497.0
HFD3_k127_1811787_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007076 454.0
HFD3_k127_1811787_5 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 383.0
HFD3_k127_1811787_6 Methyltransferase, chemotaxis proteins K00575,K13486 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 372.0
HFD3_k127_1811787_7 Enoyl-CoA hydratase/isomerase K01715,K07537 - 4.2.1.100,4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 354.0
HFD3_k127_1811787_8 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 348.0
HFD3_k127_1811787_9 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 313.0
HFD3_k127_1813427_0 Phosphate acyltransferases K01897 - 6.2.1.3 1.879e-257 819.0
HFD3_k127_1813427_1 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 494.0
HFD3_k127_1813427_10 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002074 250.0
HFD3_k127_1813427_11 Abc transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000006771 211.0
HFD3_k127_1813427_12 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000007231 217.0
HFD3_k127_1813427_13 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000001133 183.0
HFD3_k127_1813427_14 PFAM major facilitator superfamily MFS_1 K08223 - - 0.000000000000000000000000000000000000000000001127 181.0
HFD3_k127_1813427_15 transcriptional regulator containing an HTH domain and an K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000006617 176.0
HFD3_k127_1813427_16 ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000001565 151.0
HFD3_k127_1813427_17 ribosomal large subunit export from nucleus - - - 0.000000000000000000000001568 109.0
HFD3_k127_1813427_18 lysyltransferase activity K07027 - - 0.0000000000000000001101 101.0
HFD3_k127_1813427_19 Competence protein ComEA helix-hairpin-helix repeat K02237 - - 0.00000000001654 68.0
HFD3_k127_1813427_2 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007148 458.0
HFD3_k127_1813427_20 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00000008848 59.0
HFD3_k127_1813427_21 - - - - 0.000003249 55.0
HFD3_k127_1813427_22 - - - - 0.00003653 54.0
HFD3_k127_1813427_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005358 377.0
HFD3_k127_1813427_4 PFAM Helix-turn-helix, type 11 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009574 353.0
HFD3_k127_1813427_5 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008175 305.0
HFD3_k127_1813427_6 L-asparaginase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 302.0
HFD3_k127_1813427_7 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003175 265.0
HFD3_k127_1813427_8 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000002102 248.0
HFD3_k127_1813427_9 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000002432 249.0
HFD3_k127_1846992_0 Tricorn protease homolog K08676 - - 0.0 1553.0
HFD3_k127_1846992_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 4.555e-239 750.0
HFD3_k127_1846992_10 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 376.0
HFD3_k127_1846992_11 extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 366.0
HFD3_k127_1846992_12 Bacillithiol biosynthesis BshC K22136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 351.0
HFD3_k127_1846992_13 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 321.0
HFD3_k127_1846992_14 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 336.0
HFD3_k127_1846992_15 Peptidase, M16 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 318.0
HFD3_k127_1846992_16 PFAM Peptidase M16 inactive domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 310.0
HFD3_k127_1846992_17 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 295.0
HFD3_k127_1846992_18 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006152 287.0
HFD3_k127_1846992_19 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002469 287.0
HFD3_k127_1846992_2 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 610.0
HFD3_k127_1846992_20 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008675 271.0
HFD3_k127_1846992_21 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000005443 256.0
HFD3_k127_1846992_22 Belongs to the DapA family K01714,K22397 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0019520,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0047440,GO:0071704,GO:0072329,GO:1901575 4.1.2.28,4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000005713 253.0
HFD3_k127_1846992_23 COGs COG2912 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000001036 237.0
HFD3_k127_1846992_24 methylmalonyl-CoA mutase C-terminal K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000001922 209.0
HFD3_k127_1846992_25 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000007172 211.0
HFD3_k127_1846992_26 Putative esterase - - - 0.00000000000000000000000000000000000000000000000001429 192.0
HFD3_k127_1846992_27 PFAM FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000001294 174.0
HFD3_k127_1846992_28 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000003127 160.0
HFD3_k127_1846992_29 Dimerisation domain - - - 0.0000000000000000000000003655 111.0
HFD3_k127_1846992_3 PFAM Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 579.0
HFD3_k127_1846992_30 Trm112p-like protein K09791 - - 0.000000000000000000000005576 102.0
HFD3_k127_1846992_31 reductase K00059 - 1.1.1.100 0.00000000000000000000004561 109.0
HFD3_k127_1846992_32 Caspase domain - - - 0.000000000000000000008195 108.0
HFD3_k127_1846992_33 Phosphocarrier protein HPr K08485,K11189 - - 0.00000000000000000000896 94.0
HFD3_k127_1846992_34 - - - - 0.00000000000000000009862 103.0
HFD3_k127_1846992_35 Polymer-forming cytoskeletal - - - 0.0000000000000000004082 93.0
HFD3_k127_1846992_36 Methyltransferase small domain - - - 0.000000000000001489 86.0
HFD3_k127_1846992_37 PFAM glutaredoxin K18917 - 1.20.4.3 0.0000000005178 66.0
HFD3_k127_1846992_38 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000002005 59.0
HFD3_k127_1846992_39 TIGRFAM TonB K03832 - - 0.00000128 60.0
HFD3_k127_1846992_4 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 578.0
HFD3_k127_1846992_40 Domain of unknown function (DUF4190) - - - 0.0004662 49.0
HFD3_k127_1846992_41 Tetratricopeptide repeat - - - 0.0005938 52.0
HFD3_k127_1846992_5 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 522.0
HFD3_k127_1846992_6 PEP-utilising enzyme, N-terminal K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 446.0
HFD3_k127_1846992_7 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009729 425.0
HFD3_k127_1846992_8 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006477 430.0
HFD3_k127_1846992_9 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000846 388.0
HFD3_k127_1860678_0 Carboxyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 597.0
HFD3_k127_1860678_1 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961,K01965,K01968 - 6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005127 575.0
HFD3_k127_1860678_2 Acyl-CoA dehydrogenase, C-terminal domain K11731 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 497.0
HFD3_k127_1860678_3 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004518 418.0
HFD3_k127_1860678_4 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005728 323.0
HFD3_k127_1860678_5 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009021 304.0
HFD3_k127_1860678_6 Protein of unknown function (DUF664) - - - 0.00000000000000000000000000000000000000000000000000002846 197.0
HFD3_k127_1860678_7 Alpha/beta hydrolase family K07020 - - 0.00000000000000000000000000000000000000000000000002718 189.0
HFD3_k127_1860678_8 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 0.0000000000000000000000004726 112.0
HFD3_k127_1860678_9 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000008614 108.0
HFD3_k127_187223_0 von Willebrand factor, type A K07114 - - 5.807e-196 638.0
HFD3_k127_187223_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009947 417.0
HFD3_k127_187223_2 Cold shock protein K03704 - - 0.0000000000000000000000002814 107.0
HFD3_k127_187223_3 - - - - 0.00000000000000000000005033 106.0
HFD3_k127_187223_4 Protein conserved in bacteria - - - 0.00000107 60.0
HFD3_k127_1893014_0 Penicillin amidase - - - 0.0 1064.0
HFD3_k127_1893014_1 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 417.0
HFD3_k127_1893014_2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000008401 198.0
HFD3_k127_1911702_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 379.0
HFD3_k127_1911702_1 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007256 293.0
HFD3_k127_1911702_10 SatD family (SatD) - - - 0.000000000001162 76.0
HFD3_k127_1911702_11 - - - - 0.0000008985 60.0
HFD3_k127_1911702_12 hyperosmotic response - - - 0.00009892 51.0
HFD3_k127_1911702_2 Domain of unknown function (DUF3488) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002893 289.0
HFD3_k127_1911702_3 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000105 232.0
HFD3_k127_1911702_4 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000002269 222.0
HFD3_k127_1911702_5 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000004144 209.0
HFD3_k127_1911702_6 Putative cyclase K07130 - 3.5.1.9 0.000000000000000000000000000000000000000000000000000004608 196.0
HFD3_k127_1911702_7 PFAM KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000000000000000000000006576 141.0
HFD3_k127_1911702_8 Protein of unknown function (DUF3307) - - - 0.0000000000000000000000000006977 122.0
HFD3_k127_1911702_9 Roadblock/LC7 domain - - - 0.00000000000006611 76.0
HFD3_k127_1963212_0 cellulose binding - - - 0.0 1385.0
HFD3_k127_1963212_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1134.0
HFD3_k127_1963212_10 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01431 - 3.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009525 292.0
HFD3_k127_1963212_11 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003879 293.0
HFD3_k127_1963212_12 Amidohydrolase K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000002531 264.0
HFD3_k127_1963212_13 PFAM Class II aldolase adducin K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000003706 241.0
HFD3_k127_1963212_14 OsmC-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000006412 229.0
HFD3_k127_1963212_15 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000000005903 210.0
HFD3_k127_1963212_16 Belongs to the enoyl-CoA hydratase isomerase family K13766 - 4.2.1.18 0.0000000000000000000000000000000000000000000000000000000001844 214.0
HFD3_k127_1963212_17 glycolate biosynthetic process K01091,K06019,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.18,3.6.1.1 0.000000000000000000000000000000000000000000000000000001936 199.0
HFD3_k127_1963212_18 peptidase C14 caspase catalytic subunit p20 - - - 0.000000000000000000000000000000000000000000002159 179.0
HFD3_k127_1963212_19 Biotin-lipoyl like K15727 - - 0.0000000000000000000000000000000000000000003488 178.0
HFD3_k127_1963212_2 Tetratricopeptide repeat K12132 - 2.7.11.1 2.033e-271 893.0
HFD3_k127_1963212_20 - - - - 0.000000000000000000000000000000000000000006647 156.0
HFD3_k127_1963212_21 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000000000000008892 159.0
HFD3_k127_1963212_22 Protein of unknown function (DUF4242) - - - 0.00000000000000000000000000000000008057 134.0
HFD3_k127_1963212_23 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.0000000000000000000000000000000005569 134.0
HFD3_k127_1963212_24 BMC - - - 0.00000000000000000000000000000000147 134.0
HFD3_k127_1963212_25 Thioesterase superfamily - - - 0.000000000000000000000000000003017 124.0
HFD3_k127_1963212_26 Transposase IS200 like K07491 - - 0.000000000000000000000000000007239 124.0
HFD3_k127_1963212_27 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.000000000000000000000000001947 113.0
HFD3_k127_1963212_28 PFAM Iron sulphur-containing domain, CDGSH-type - - - 0.00000000000000000000000214 104.0
HFD3_k127_1963212_29 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000002166 104.0
HFD3_k127_1963212_3 Acyclic terpene utilisation family protein AtuA - - - 1.944e-197 624.0
HFD3_k127_1963212_30 PFAM Outer membrane efflux protein K15725 - - 0.0000000000000000000009312 109.0
HFD3_k127_1963212_31 - - - - 0.00000000000000000244 91.0
HFD3_k127_1963212_32 - - - - 0.000000000000000002654 89.0
HFD3_k127_1963212_33 Cupredoxin-like domain - - - 0.00000000000001283 87.0
HFD3_k127_1963212_34 Methyltransferase domain - - - 0.00000000000002328 78.0
HFD3_k127_1963212_35 Transposase - - - 0.00003149 46.0
HFD3_k127_1963212_4 Belongs to the xylose isomerase family K01805 - 5.3.1.5 4.143e-197 620.0
HFD3_k127_1963212_5 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008891 600.0
HFD3_k127_1963212_6 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005575 499.0
HFD3_k127_1963212_7 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 398.0
HFD3_k127_1963212_8 Amidohydrolase family K12960,K20810 - 3.5.4.28,3.5.4.31,3.5.4.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 376.0
HFD3_k127_1963212_9 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006502 364.0
HFD3_k127_196439_0 Sodium:solute symporter family - - - 1.239e-278 871.0
HFD3_k127_196439_1 efflux transmembrane transporter activity K02004 - - 3.44e-214 691.0
HFD3_k127_196439_10 Peptidase family M54 K06974 - - 0.000000000000000000000000000000000000001694 154.0
HFD3_k127_196439_11 PFAM glycine cleavage H-protein - - - 0.00000000000000000000000000000063 134.0
HFD3_k127_196439_12 Glycine cleavage H-protein - - - 0.000000000000000000000000313 113.0
HFD3_k127_196439_13 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000001167 88.0
HFD3_k127_196439_14 - - - - 0.0000000000000008044 78.0
HFD3_k127_196439_16 - - - - 0.000004929 52.0
HFD3_k127_196439_2 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 600.0
HFD3_k127_196439_3 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000901 547.0
HFD3_k127_196439_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 468.0
HFD3_k127_196439_5 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 446.0
HFD3_k127_196439_6 Belongs to the GHMP kinase family K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 355.0
HFD3_k127_196439_7 4 iron, 4 sulfur cluster binding K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 313.0
HFD3_k127_196439_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000009155 235.0
HFD3_k127_196439_9 PFAM Cupin 2 conserved barrel domain protein K05913 - 1.13.11.41 0.000000000000000000000000000000000000000000000002644 178.0
HFD3_k127_2007572_0 ASPIC and UnbV - - - 4.364e-256 800.0
HFD3_k127_2007572_1 peptidyl-tyrosine sulfation - - - 5.71e-220 697.0
HFD3_k127_2007572_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 317.0
HFD3_k127_2007572_3 PFAM Enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000003865 268.0
HFD3_k127_2007572_4 COG0657 Esterase lipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001845 261.0
HFD3_k127_2007572_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000003685 236.0
HFD3_k127_2007572_6 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000009142 90.0
HFD3_k127_2007572_7 COG3209 Rhs family protein - - - 0.0000000003042 71.0
HFD3_k127_2007572_8 PFAM Na dependent nucleoside transporter K03317 - - 0.0000005619 53.0
HFD3_k127_20416_0 MFS/sugar transport protein K16211 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 613.0
HFD3_k127_20416_1 Cyclomaltodextrinase, N-terminal K21575 - 3.2.1.135 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 390.0
HFD3_k127_20416_2 Glycogen debranching enzyme, glucanotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 334.0
HFD3_k127_20416_3 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000002801 66.0
HFD3_k127_21275_0 Belongs to the ClpA ClpB family K03696 - - 0.0 1110.0
HFD3_k127_21275_1 radical SAM domain protein - - - 2.282e-285 887.0
HFD3_k127_21275_10 Aromatic amino acid lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005013 560.0
HFD3_k127_21275_11 COG0471 Di- and tricarboxylate transporters - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 553.0
HFD3_k127_21275_12 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 549.0
HFD3_k127_21275_13 succinyl-diaminopimelate desuccinylase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006521 533.0
HFD3_k127_21275_14 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000495 527.0
HFD3_k127_21275_15 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 540.0
HFD3_k127_21275_16 Elongation factor SelB, winged helix K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004113 533.0
HFD3_k127_21275_17 cystathionine gamma-synthase activity K01758,K01760,K01761 - 4.4.1.1,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 486.0
HFD3_k127_21275_18 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008606 482.0
HFD3_k127_21275_19 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 474.0
HFD3_k127_21275_2 Urocanase Rossmann-like domain K01712 - 4.2.1.49 2.029e-277 863.0
HFD3_k127_21275_20 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 473.0
HFD3_k127_21275_21 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005289 473.0
HFD3_k127_21275_22 TIGRFAM outer membrane protein assembly complex, YaeT protein K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 475.0
HFD3_k127_21275_23 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007377 442.0
HFD3_k127_21275_24 protein-disulfide reductase activity K04084,K06196 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000767 459.0
HFD3_k127_21275_25 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000084 421.0
HFD3_k127_21275_26 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 419.0
HFD3_k127_21275_27 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 414.0
HFD3_k127_21275_28 amine oxidase K00276 - 1.4.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 414.0
HFD3_k127_21275_29 Permease, YjgP YjgQ - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 406.0
HFD3_k127_21275_3 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 3.36e-248 780.0
HFD3_k127_21275_30 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 367.0
HFD3_k127_21275_31 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008795 383.0
HFD3_k127_21275_32 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 335.0
HFD3_k127_21275_33 MacB-like periplasmic core domain K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 324.0
HFD3_k127_21275_34 Ornithine cyclodeaminase/mu-crystallin family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009252 317.0
HFD3_k127_21275_35 PFAM PP-loop domain protein K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 298.0
HFD3_k127_21275_36 Belongs to the PdxA family K22024 - 1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004756 290.0
HFD3_k127_21275_37 Protein of unknown function (DUF1009) K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000111 283.0
HFD3_k127_21275_38 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009268 291.0
HFD3_k127_21275_39 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001187 279.0
HFD3_k127_21275_4 Zinc carboxypeptidase - - - 5.417e-208 680.0
HFD3_k127_21275_40 Flavin containing amine oxidoreductase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000005724 278.0
HFD3_k127_21275_41 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000064 268.0
HFD3_k127_21275_42 Squalene/phytoene synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004988 259.0
HFD3_k127_21275_43 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000001327 258.0
HFD3_k127_21275_44 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000002934 261.0
HFD3_k127_21275_45 thiolester hydrolase activity K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000232 254.0
HFD3_k127_21275_46 Stage II sporulation protein M - - - 0.0000000000000000000000000000000000000000000000000000000000001929 224.0
HFD3_k127_21275_47 sugar phosphate isomerase involved in capsule formation K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000001759 216.0
HFD3_k127_21275_48 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000000000000001129 198.0
HFD3_k127_21275_49 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000000000002411 187.0
HFD3_k127_21275_5 Peptidase family M28 - - - 1.082e-206 662.0
HFD3_k127_21275_50 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000003837 193.0
HFD3_k127_21275_51 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000129 187.0
HFD3_k127_21275_52 YjbR - - - 0.000000000000000000000000000000000000000000000003765 177.0
HFD3_k127_21275_53 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000006018 182.0
HFD3_k127_21275_54 CarD-like/TRCF domain K07736 - - 0.000000000000000000000000000000000001876 145.0
HFD3_k127_21275_55 von Willebrand factor (vWF) type A domain K07114 - - 0.00000000000000000000000000000000004127 148.0
HFD3_k127_21275_56 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000008232 138.0
HFD3_k127_21275_57 PFAM RNA recognition motif - - - 0.00000000000000000000000000215 115.0
HFD3_k127_21275_58 Hfq protein - - - 0.0000000000000000000000000133 113.0
HFD3_k127_21275_59 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000008546 109.0
HFD3_k127_21275_6 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 7.49e-203 642.0
HFD3_k127_21275_60 NUDIX domain K08310 - 3.6.1.67 0.000000000000000000000001731 108.0
HFD3_k127_21275_61 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.000000000000000000000001733 121.0
HFD3_k127_21275_62 YceI-like domain - - - 0.00000000000000000000002101 109.0
HFD3_k127_21275_63 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000004594 115.0
HFD3_k127_21275_64 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000007888 96.0
HFD3_k127_21275_65 Putative phosphatase (DUF442) - - - 0.0000000000000000002788 94.0
HFD3_k127_21275_66 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000000006226 87.0
HFD3_k127_21275_67 Transcriptional regulator K07506 - - 0.0000000000000002396 85.0
HFD3_k127_21275_68 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000005155 91.0
HFD3_k127_21275_69 Carboxypeptidase regulatory-like domain - - - 0.00000000000001571 85.0
HFD3_k127_21275_7 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 575.0
HFD3_k127_21275_70 NUDIX domain - - - 0.0000000001018 69.0
HFD3_k127_21275_71 - - - - 0.00000000013 63.0
HFD3_k127_21275_72 Outer membrane protein (OmpH-like) K06142 - - 0.000000003721 66.0
HFD3_k127_21275_73 NosL - - - 0.000000005087 64.0
HFD3_k127_21275_74 Outer membrane protein (OmpH-like) K06142 - - 0.000005564 56.0
HFD3_k127_21275_76 Domain of unknown function (DUF4388) - - - 0.00007967 53.0
HFD3_k127_21275_77 Belongs to the AAA ATPase family K03798 - - 0.0003351 51.0
HFD3_k127_21275_78 YjbR - - - 0.0007624 50.0
HFD3_k127_21275_8 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 562.0
HFD3_k127_21275_9 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 565.0
HFD3_k127_2142175_0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 3.089e-291 912.0
HFD3_k127_2142175_1 Cyclomaltodextrinase, N-terminal K21575 - 3.2.1.135 1.717e-210 668.0
HFD3_k127_2211346_0 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.0 1110.0
HFD3_k127_2211346_1 B12 binding domain - - - 3.711e-238 746.0
HFD3_k127_2211346_10 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003911 411.0
HFD3_k127_2211346_11 PFAM Ribonuclease BN-like family K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 372.0
HFD3_k127_2211346_12 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 323.0
HFD3_k127_2211346_13 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 313.0
HFD3_k127_2211346_14 Metallopeptidase family M24 K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 313.0
HFD3_k127_2211346_15 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 298.0
HFD3_k127_2211346_16 Haem-degrading - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002252 300.0
HFD3_k127_2211346_17 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000441 282.0
HFD3_k127_2211346_18 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001673 267.0
HFD3_k127_2211346_19 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003965 266.0
HFD3_k127_2211346_2 Transcriptional regulator K06921 - - 4.139e-228 737.0
HFD3_k127_2211346_20 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000654 264.0
HFD3_k127_2211346_21 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001441 268.0
HFD3_k127_2211346_22 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000001138 224.0
HFD3_k127_2211346_23 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.000000000000000000000000000000000000000000000000000000000000007974 222.0
HFD3_k127_2211346_24 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000001831 233.0
HFD3_k127_2211346_25 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000008993 217.0
HFD3_k127_2211346_26 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000000000472 215.0
HFD3_k127_2211346_27 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000001482 217.0
HFD3_k127_2211346_28 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000000000005673 193.0
HFD3_k127_2211346_29 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000001022 194.0
HFD3_k127_2211346_3 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 594.0
HFD3_k127_2211346_30 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000003372 190.0
HFD3_k127_2211346_31 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000007517 181.0
HFD3_k127_2211346_32 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000000000002539 179.0
HFD3_k127_2211346_33 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000007815 194.0
HFD3_k127_2211346_34 Peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000005759 174.0
HFD3_k127_2211346_35 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788,K14153 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3,2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000006088 173.0
HFD3_k127_2211346_36 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000002794 169.0
HFD3_k127_2211346_37 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000000000000000000000000000114 176.0
HFD3_k127_2211346_38 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000002709 152.0
HFD3_k127_2211346_39 Bacterial-like globin K06886 - - 0.0000000000000000000000000000000000000003337 153.0
HFD3_k127_2211346_4 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009241 595.0
HFD3_k127_2211346_40 Lysin motif - - - 0.00000000000000000000000000000000000000695 152.0
HFD3_k127_2211346_41 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000002145 146.0
HFD3_k127_2211346_42 DinB superfamily K07552 - - 0.000000000000000000000000000000000001691 144.0
HFD3_k127_2211346_43 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.0000000000000000000000000000000000938 138.0
HFD3_k127_2211346_44 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000007285 133.0
HFD3_k127_2211346_45 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000003047 135.0
HFD3_k127_2211346_46 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000001029 125.0
HFD3_k127_2211346_47 HAD-hyrolase-like K07025 - - 0.000000000000000000000000000002224 131.0
HFD3_k127_2211346_48 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000001808 127.0
HFD3_k127_2211346_49 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000003706 105.0
HFD3_k127_2211346_5 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 584.0
HFD3_k127_2211346_50 Thioredoxin - - - 0.0000000000000000001224 103.0
HFD3_k127_2211346_51 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000003577 91.0
HFD3_k127_2211346_52 GrpB protein - - - 0.000000000000000003555 92.0
HFD3_k127_2211346_53 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000115 82.0
HFD3_k127_2211346_54 Ribosomal protein L30 K02907 - - 0.0000000000000003463 79.0
HFD3_k127_2211346_55 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000009548 79.0
HFD3_k127_2211346_56 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000001576 74.0
HFD3_k127_2211346_57 Ribosomal L29 protein K02904 - - 0.0000000001668 66.0
HFD3_k127_2211346_58 IMG reference gene - - - 0.0000000002666 70.0
HFD3_k127_2211346_59 Putative zinc- or iron-chelating domain K06940 - - 0.00001708 52.0
HFD3_k127_2211346_6 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 512.0
HFD3_k127_2211346_60 Protein of unknown function (DUF1573) - - - 0.0001569 48.0
HFD3_k127_2211346_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004367 472.0
HFD3_k127_2211346_8 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008622 467.0
HFD3_k127_2211346_9 glycogen (starch) synthase activity K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 443.0
HFD3_k127_225819_0 MgtE intracellular N domain K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006819 571.0
HFD3_k127_225819_1 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 541.0
HFD3_k127_225819_10 methyltransferase activity - - - 0.0000000000000000000000001792 114.0
HFD3_k127_225819_11 Amidohydrolase family - - - 0.00000000000000004328 85.0
HFD3_k127_225819_12 Putative peptidoglycan binding domain K17733 - - 0.0000006769 56.0
HFD3_k127_225819_13 von Willebrand factor (vWF) type A domain K07114 - - 0.000001554 52.0
HFD3_k127_225819_15 Zn peptidase - - - 0.0001181 52.0
HFD3_k127_225819_16 E1-E2 ATPase K01531 - 3.6.3.2 0.0003276 44.0
HFD3_k127_225819_2 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 508.0
HFD3_k127_225819_3 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 383.0
HFD3_k127_225819_4 PFAM Short-chain dehydrogenase reductase SDR K00059,K00076 - 1.1.1.100,1.1.1.159 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001567 274.0
HFD3_k127_225819_5 response to heat K03695,K03696,K03697,K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001084 271.0
HFD3_k127_225819_6 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000003736 221.0
HFD3_k127_225819_7 Acyl-transferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000001127 205.0
HFD3_k127_225819_8 - - - - 0.000000000000000000000000000000002579 134.0
HFD3_k127_225819_9 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 0.00000000000000000000000002545 113.0
HFD3_k127_2330646_0 TonB dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 476.0
HFD3_k127_2330646_1 Sodium/calcium exchanger protein K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 370.0
HFD3_k127_2330646_2 protein-glutamate O-methyltransferase activity K00575,K03408,K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 374.0
HFD3_k127_2330646_3 peptidyl-tyrosine sulfation - - - 0.00000000000000000007935 102.0
HFD3_k127_2330646_4 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0002535 53.0
HFD3_k127_2335164_0 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 569.0
HFD3_k127_2335164_1 COG0477 Permeases of the major facilitator superfamily K05820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 537.0
HFD3_k127_2335164_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 494.0
HFD3_k127_2335164_3 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 424.0
HFD3_k127_2335164_4 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K21310 - 2.1.1.334 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001997 281.0
HFD3_k127_2335164_5 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000004421 196.0
HFD3_k127_2335369_0 Cysteine-rich domain K00113 - 1.1.5.3 2.91e-209 658.0
HFD3_k127_2335369_1 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 9.27e-209 657.0
HFD3_k127_2335369_10 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000835 436.0
HFD3_k127_2335369_11 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004838 422.0
HFD3_k127_2335369_12 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008482 406.0
HFD3_k127_2335369_13 COG0842 ABC-type multidrug transport system, permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 372.0
HFD3_k127_2335369_14 ABC-type multidrug transport system ATPase component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 363.0
HFD3_k127_2335369_15 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 383.0
HFD3_k127_2335369_16 phosphate acetyltransferase K00625 GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 349.0
HFD3_k127_2335369_17 Peptidase dimerisation domain protein K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007427 345.0
HFD3_k127_2335369_18 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 312.0
HFD3_k127_2335369_19 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 309.0
HFD3_k127_2335369_2 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006908 606.0
HFD3_k127_2335369_20 galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005995 303.0
HFD3_k127_2335369_21 HlyD family secretion protein K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001364 291.0
HFD3_k127_2335369_22 PFAM PHP domain K07053,K20859 - 3.1.3.97,3.1.4.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001505 283.0
HFD3_k127_2335369_23 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004017 273.0
HFD3_k127_2335369_24 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000002188 264.0
HFD3_k127_2335369_25 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001643 253.0
HFD3_k127_2335369_26 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001548 233.0
HFD3_k127_2335369_27 xylan catabolic process K03932 - - 0.0000000000000000000000000000000000000000000000000000000000000003928 230.0
HFD3_k127_2335369_28 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000000000000000000000000000000000000005301 225.0
HFD3_k127_2335369_29 Cys-tRNA(Pro) hydrolase activity K03976 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0043906,GO:0043907,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000154 220.0
HFD3_k127_2335369_3 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005177 582.0
HFD3_k127_2335369_30 YceI-like domain - - - 0.000000000000000000000000000000000000000000000000000000000001511 240.0
HFD3_k127_2335369_31 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000002638 207.0
HFD3_k127_2335369_32 nucleotide metabolic process - - - 0.000000000000000000000000000000000000000000000000000009652 198.0
HFD3_k127_2335369_33 Roadblock/LC7 domain - - - 0.00000000000000000000000000000000000000000000000000001429 192.0
HFD3_k127_2335369_34 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000004504 193.0
HFD3_k127_2335369_35 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000001114 181.0
HFD3_k127_2335369_36 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000000008221 190.0
HFD3_k127_2335369_37 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000000000000000221 175.0
HFD3_k127_2335369_38 Cupin 2, conserved barrel domain protein K01809,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000006421 154.0
HFD3_k127_2335369_39 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000006494 140.0
HFD3_k127_2335369_4 PFAM TonB-dependent Receptor Plug - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 561.0
HFD3_k127_2335369_40 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000002553 139.0
HFD3_k127_2335369_41 Beta-lactamase enzyme family - - - 0.0000000000000000000000000000000002993 143.0
HFD3_k127_2335369_42 PFAM Lytic transglycosylase catalytic K08309 - - 0.000000000000000000000000004057 129.0
HFD3_k127_2335369_43 domain, Protein - - - 0.00000000000000000000000000503 130.0
HFD3_k127_2335369_44 TIGRFAM TonB K03832 - - 0.000000000000000000000000396 117.0
HFD3_k127_2335369_45 PFAM Uncharacterised BCR, COG1649 - - - 0.0000000000000000000000004138 124.0
HFD3_k127_2335369_46 Belongs to the Fur family K09825 - - 0.000000000000000000000002991 109.0
HFD3_k127_2335369_47 Bacterial regulatory proteins, tetR family K09017 - - 0.00000000000000000000000459 112.0
HFD3_k127_2335369_48 Putative bacterial sensory transduction regulator - - - 0.000000000000000000000006566 107.0
HFD3_k127_2335369_49 Biotin-requiring enzyme - - - 0.000000000000000000001518 103.0
HFD3_k127_2335369_5 FecR protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 507.0
HFD3_k127_2335369_50 Belongs to the UPF0102 family K07460 - - 0.00000000000007695 79.0
HFD3_k127_2335369_51 Sigma-70, region 4 K03088 - - 0.0000000000002365 78.0
HFD3_k127_2335369_52 Roadblock/LC7 domain - - - 0.00000000493 62.0
HFD3_k127_2335369_53 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.000003778 58.0
HFD3_k127_2335369_54 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000006036 55.0
HFD3_k127_2335369_55 Protein of unknown function (DUF3225) - - - 0.00001508 53.0
HFD3_k127_2335369_56 - - - - 0.0001474 50.0
HFD3_k127_2335369_57 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0003243 52.0
HFD3_k127_2335369_6 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008803 487.0
HFD3_k127_2335369_7 Lamin Tail Domain K07004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 518.0
HFD3_k127_2335369_8 virulence factor MVIN family protein K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 476.0
HFD3_k127_2335369_9 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 447.0
HFD3_k127_2340726_0 Belongs to the glycosyl hydrolase 30 family K01201 - 3.2.1.45 2.989e-231 724.0
HFD3_k127_2340726_1 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 419.0
HFD3_k127_2352089_0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 1.515e-197 623.0
HFD3_k127_2352089_1 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 592.0
HFD3_k127_2352089_10 Lipopolysaccharide-assembly - - - 0.000000000000000000000000009765 117.0
HFD3_k127_2352089_11 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000001906 79.0
HFD3_k127_2352089_2 S-adenosylmethionine synthetase, C-terminal domain K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 569.0
HFD3_k127_2352089_3 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005188 345.0
HFD3_k127_2352089_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 334.0
HFD3_k127_2352089_5 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 311.0
HFD3_k127_2352089_6 Extradiol ring-cleavage dioxygenase, class III K06990,K09141 - - 0.000000000000000000000000000000000000000000000000000000004509 209.0
HFD3_k127_2352089_7 Psort location Cytoplasmic, score 8.96 - - - 0.00000000000000000000000000000000000000007624 158.0
HFD3_k127_2352089_8 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.0000000000000000000000000000005745 126.0
HFD3_k127_2352089_9 DNA-directed DNA polymerase activity K02340 - 2.7.7.7 0.000000000000000000000000002509 124.0
HFD3_k127_2370878_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004196 517.0
HFD3_k127_2370878_1 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 344.0
HFD3_k127_2370878_2 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 331.0
HFD3_k127_2370878_3 phosphoserine phosphatase activity K07315,K16928 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000001256 222.0
HFD3_k127_2370878_4 Protein of unknown function (DUF3455) - - - 0.0000000000000000000000000547 114.0
HFD3_k127_2370878_5 SnoaL-like polyketide cyclase - - - 0.00000000000000001773 82.0
HFD3_k127_2370878_6 Hep Hag repeat protein - - - 0.00000000001341 76.0
HFD3_k127_2428253_0 Belongs to the glycosyl hydrolase 3 family K05349 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0008422,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0015926,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899 3.2.1.21 3.301e-256 811.0
HFD3_k127_2428253_1 ASPIC and UnbV - - - 3.432e-228 719.0
HFD3_k127_2428253_10 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002946 262.0
HFD3_k127_2428253_11 PFAM ROK family - - - 0.000000000000000000000000000000000000000000000000000000000000000000004267 249.0
HFD3_k127_2428253_12 - - - - 0.00000000000000000000000000000000000000000000000000002752 214.0
HFD3_k127_2428253_13 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000297 113.0
HFD3_k127_2428253_14 Tetratricopeptide repeat - - - 0.00009614 54.0
HFD3_k127_2428253_15 DinB family - - - 0.0003851 45.0
HFD3_k127_2428253_2 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 603.0
HFD3_k127_2428253_3 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 534.0
HFD3_k127_2428253_4 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 517.0
HFD3_k127_2428253_5 Oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007113 459.0
HFD3_k127_2428253_6 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 387.0
HFD3_k127_2428253_7 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008089 326.0
HFD3_k127_2428253_8 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009606 309.0
HFD3_k127_2428253_9 Trehalose utilisation K09992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 289.0
HFD3_k127_2431858_0 Baseplate J-like protein - - - 0.0 1236.0
HFD3_k127_2431858_1 Phage tail protein (Tail_P2_I) - - - 2.462e-227 728.0
HFD3_k127_2431858_10 T4-like virus tail tube protein gp19 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002432 278.0
HFD3_k127_2431858_11 Protein of unknown function (DUF4255) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001317 261.0
HFD3_k127_2431858_12 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000005249 238.0
HFD3_k127_2431858_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000009573 237.0
HFD3_k127_2431858_14 Tail protein - - - 0.000000000000000000000000000000000000000000000000000000000000005713 229.0
HFD3_k127_2431858_15 Sodium Bile acid symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000004102 220.0
HFD3_k127_2431858_16 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000000000000000000000000000000002491 215.0
HFD3_k127_2431858_18 - - - - 0.00000000000000000000000000000000000000000000000000000859 191.0
HFD3_k127_2431858_19 Gene 25-like lysozyme K06903 - - 0.000000000000000000000000000000000000000000000000001824 188.0
HFD3_k127_2431858_2 Baseplate J-like protein - - - 6.053e-202 652.0
HFD3_k127_2431858_20 - - - - 0.00000000000000000000000000000000000000000000000000305 194.0
HFD3_k127_2431858_21 Rhs element vgr protein - - - 0.00000000000000000000000000000000000000000000002119 179.0
HFD3_k127_2431858_23 - - - - 0.00000000000000000000000000000000000000001708 160.0
HFD3_k127_2431858_24 PAAR motif - - - 0.000000000000000000000000000000000003147 139.0
HFD3_k127_2431858_25 cheY-homologous receiver domain - - - 0.000000000000000000000000005753 116.0
HFD3_k127_2431858_26 chlorophyll binding - - - 0.0000000000000000000000004461 117.0
HFD3_k127_2431858_27 Belongs to the ompA family - - - 0.00000000000000000105 97.0
HFD3_k127_2431858_28 - - - - 0.0000000000000002521 80.0
HFD3_k127_2431858_29 - - - - 0.0000000001951 72.0
HFD3_k127_2431858_3 Late control gene D protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008186 554.0
HFD3_k127_2431858_30 Domain of unknown function (DUF4956) - - - 0.0000000008783 70.0
HFD3_k127_2431858_31 Evidence 4 Homologs of previously reported genes of - - - 0.000000004827 65.0
HFD3_k127_2431858_4 Phage tail sheath C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 479.0
HFD3_k127_2431858_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 355.0
HFD3_k127_2431858_6 LysM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 338.0
HFD3_k127_2431858_7 phage tail tape measure protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007188 342.0
HFD3_k127_2431858_8 domain, Protein K15125 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 300.0
HFD3_k127_2431858_9 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000933 301.0
HFD3_k127_2462420_0 Belongs to the TPP enzyme family K03336 GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009395,GO:0009987,GO:0016042,GO:0019637,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0046434,GO:0071704,GO:1901575 3.7.1.22 1.567e-255 801.0
HFD3_k127_2462420_1 pfkB family carbohydrate kinase K03338 - 2.7.1.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 462.0
HFD3_k127_2462420_2 helix_turn _helix lactose operon repressor K05499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000387 437.0
HFD3_k127_2462420_3 lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 427.0
HFD3_k127_2462420_4 enzyme involved in inositol metabolism K03337 - 5.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004642 412.0
HFD3_k127_2462420_5 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000000000000000000000000000000000001157 210.0
HFD3_k127_2478618_0 cellulose binding - - - 0.0 1066.0
HFD3_k127_2478618_1 Domain of unknown function (DUF3471) - - - 8.391e-196 623.0
HFD3_k127_2478618_10 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000001448 231.0
HFD3_k127_2478618_11 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000009592 225.0
HFD3_k127_2478618_12 PFAM Mammalian cell entry related domain protein K02067 - - 0.000000000000000000000000000000000000000000000000000002468 205.0
HFD3_k127_2478618_13 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000006399 179.0
HFD3_k127_2478618_15 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000001012 99.0
HFD3_k127_2478618_16 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000001105 78.0
HFD3_k127_2478618_2 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 456.0
HFD3_k127_2478618_3 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000536 406.0
HFD3_k127_2478618_4 Enoyl- acyl-carrier-protein reductase NADH K00208 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0033554,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0055114,GO:0065003,GO:0070417,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 306.0
HFD3_k127_2478618_5 Belongs to the MlaE permease family K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001421 263.0
HFD3_k127_2478618_6 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000003571 261.0
HFD3_k127_2478618_7 PFAM WD domain, G-beta repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003044 277.0
HFD3_k127_2478618_8 ADP-heptose-lipopolysaccharide heptosyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004027 259.0
HFD3_k127_2478618_9 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000003971 240.0
HFD3_k127_2516294_0 TonB dependent receptor - - - 2.836e-242 781.0
HFD3_k127_2516294_1 Dipeptidyl peptidase IV (DPP IV) N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 617.0
HFD3_k127_2516294_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 336.0
HFD3_k127_2516294_12 -acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000005378 205.0
HFD3_k127_2516294_13 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000008102 203.0
HFD3_k127_2516294_14 Cyclic nucleotide-monophosphate binding domain K10914 - - 0.0000000000000000000000000000000000000000000000000005663 193.0
HFD3_k127_2516294_15 Transcriptional regulator, Crp Fnr family K10914 - - 0.00000000000000000000000000000000000000000000000001128 188.0
HFD3_k127_2516294_16 Peptidase family M23 K21472 - - 0.00000000000000000000000000000000000000000000000003658 186.0
HFD3_k127_2516294_17 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000001961 184.0
HFD3_k127_2516294_18 - - - - 0.000000000000000000000000000000000000000000000003608 186.0
HFD3_k127_2516294_19 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000005267 177.0
HFD3_k127_2516294_2 NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 567.0
HFD3_k127_2516294_20 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000002562 175.0
HFD3_k127_2516294_21 Highly conserved protein containing a thioredoxin domain K18581 - 3.2.1.180 0.0000000000000000000000000000000000000000000243 166.0
HFD3_k127_2516294_22 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000002352 168.0
HFD3_k127_2516294_23 Photosynthesis system II assembly factor YCF48 - - - 0.000000000000000000000000000000000002081 152.0
HFD3_k127_2516294_24 TonB dependent receptor K02014,K16087 - - 0.0000000000000000000000000000000002807 153.0
HFD3_k127_2516294_25 domain, Protein K07004 - - 0.0000000000000000000000000000000005183 153.0
HFD3_k127_2516294_26 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000006061 138.0
HFD3_k127_2516294_27 guanyl-nucleotide exchange factor activity K06978,K12287,K21105 - 3.1.1.102 0.0000000000000000000000000000000009004 152.0
HFD3_k127_2516294_28 ABC-2 family transporter protein - - - 0.00000000000000000000000000000001613 131.0
HFD3_k127_2516294_29 Cupin 2, conserved barrel domain protein K18991 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009438,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019243,GO:0019249,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046185,GO:0046394,GO:0051596,GO:0061727,GO:0071704,GO:0072330,GO:1901575,GO:1901576,GO:1901615,GO:1901617 - 0.000000000000000000000000003043 115.0
HFD3_k127_2516294_3 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 542.0
HFD3_k127_2516294_31 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K00340 - 1.6.5.3 0.0000000000000000000000001772 111.0
HFD3_k127_2516294_32 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000000000000197 106.0
HFD3_k127_2516294_33 Transglycosylase associated protein - - - 0.000000000000000000000002466 104.0
HFD3_k127_2516294_34 SnoaL-like polyketide cyclase - - - 0.00000000000000000000005866 102.0
HFD3_k127_2516294_35 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000003579 96.0
HFD3_k127_2516294_36 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000005451 100.0
HFD3_k127_2516294_37 Response regulator, receiver K06147 - - 0.0000000000000000123 87.0
HFD3_k127_2516294_38 Response regulator, receiver - - - 0.00000000000000002006 87.0
HFD3_k127_2516294_39 - - - - 0.0000000000007093 69.0
HFD3_k127_2516294_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 519.0
HFD3_k127_2516294_40 Osmotically inducible protein Y K04065 GO:0005575,GO:0005623,GO:0006457,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0050896,GO:0061077 - 0.000000000006898 74.0
HFD3_k127_2516294_41 Pyruvate phosphate dikinase - - - 0.00000000000728 66.0
HFD3_k127_2516294_42 ErfK ybiS ycfS ynhG family protein K16291 - - 0.00000000008438 74.0
HFD3_k127_2516294_44 MacB-like periplasmic core domain - - - 0.000000007847 58.0
HFD3_k127_2516294_45 Putative zinc-finger K03088 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0002277 51.0
HFD3_k127_2516294_46 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.0004488 47.0
HFD3_k127_2516294_5 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 512.0
HFD3_k127_2516294_6 acyl-CoA dehydrogenase activity K00248,K00253 - 1.3.8.1,1.3.8.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000624 477.0
HFD3_k127_2516294_7 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 458.0
HFD3_k127_2516294_8 Proton-conducting membrane transporter K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 426.0
HFD3_k127_2516294_9 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 359.0
HFD3_k127_2543722_0 UvrD/REP helicase N-terminal domain - - - 0.0 1093.0
HFD3_k127_2543722_1 PD-(D/E)XK nuclease superfamily - - - 3.119e-290 926.0
HFD3_k127_2543722_10 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 334.0
HFD3_k127_2543722_11 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 330.0
HFD3_k127_2543722_12 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 314.0
HFD3_k127_2543722_13 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007153 310.0
HFD3_k127_2543722_14 Trypsin K08070,K08372 - 1.3.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 301.0
HFD3_k127_2543722_15 PFAM ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000005008 272.0
HFD3_k127_2543722_16 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005549 263.0
HFD3_k127_2543722_17 tail specific protease K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000002594 258.0
HFD3_k127_2543722_18 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000003437 243.0
HFD3_k127_2543722_19 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation K16899 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000009651 234.0
HFD3_k127_2543722_2 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 526.0
HFD3_k127_2543722_20 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000001128 162.0
HFD3_k127_2543722_21 diguanylate cyclase - - - 0.000000000000000000000000000000000000002794 171.0
HFD3_k127_2543722_22 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000133 154.0
HFD3_k127_2543722_23 helix_turn_helix, arabinose operon control protein K07506 - - 0.0000000000000000000000000000003251 134.0
HFD3_k127_2543722_24 HD domain - - - 0.000000000000000000000000008166 127.0
HFD3_k127_2543722_25 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.00000000000000000000000008078 112.0
HFD3_k127_2543722_26 Receptor family ligand binding region K01999 - - 0.000000000000000000000001455 122.0
HFD3_k127_2543722_27 DNA polymerase Ligase (LigD) - - - 0.0000000000000000000009691 96.0
HFD3_k127_2543722_28 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.0000000000000000003012 99.0
HFD3_k127_2543722_29 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000005458 98.0
HFD3_k127_2543722_3 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008576 480.0
HFD3_k127_2543722_30 Fe2 transport system protein A K04758 - - 0.00000000002586 66.0
HFD3_k127_2543722_31 - - - - 0.000000001483 69.0
HFD3_k127_2543722_32 Protein of unknown function (DUF3341) - - - 0.0000006007 57.0
HFD3_k127_2543722_33 Tetratricopeptide repeat - - - 0.000001605 62.0
HFD3_k127_2543722_4 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 463.0
HFD3_k127_2543722_5 ferrous iron transmembrane transporter activity K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007977 473.0
HFD3_k127_2543722_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 458.0
HFD3_k127_2543722_7 spermidine synthase activity K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 466.0
HFD3_k127_2543722_8 PD-(D/E)XK nuclease superfamily K16898 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003769 417.0
HFD3_k127_2543722_9 desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 357.0
HFD3_k127_2565768_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K03737 - 1.2.7.1 0.0 1760.0
HFD3_k127_2565768_1 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1145.0
HFD3_k127_2565768_10 cyclic nucleotide-binding K01420,K10914 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004596 309.0
HFD3_k127_2565768_11 transcriptional regulator K21900 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008833 307.0
HFD3_k127_2565768_12 PFAM ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 289.0
HFD3_k127_2565768_13 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000001909 233.0
HFD3_k127_2565768_14 Caulimovirus viroplasmin K06993 - - 0.00000000000000000000000000000000000000000000000000000000000000001037 237.0
HFD3_k127_2565768_16 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000005304 195.0
HFD3_k127_2565768_17 MASE1 - - - 0.000000000000000000000000000000000002094 146.0
HFD3_k127_2565768_19 Evidence 4 Homologs of previously reported genes of K21440 - - 0.00000000000000000002488 97.0
HFD3_k127_2565768_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1062.0
HFD3_k127_2565768_20 Acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 0.000000000000000005258 87.0
HFD3_k127_2565768_3 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 552.0
HFD3_k127_2565768_4 Mate efflux family protein K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 536.0
HFD3_k127_2565768_5 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 465.0
HFD3_k127_2565768_6 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006741 367.0
HFD3_k127_2565768_7 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009145 351.0
HFD3_k127_2565768_8 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 335.0
HFD3_k127_2565768_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 343.0
HFD3_k127_2636679_0 PFAM FAD linked oxidase domain protein K00803 - 2.5.1.26 1.722e-204 646.0
HFD3_k127_2636679_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 413.0
HFD3_k127_2636679_10 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000006365 74.0
HFD3_k127_2636679_11 Glycosyl transferase family 41 - - - 0.000356 53.0
HFD3_k127_2636679_2 Zinc metalloprotease (Elastase) K01186,K05994,K21449 - 3.2.1.18,3.4.11.10 0.000000000000000000000000000000000000000000000000000000000000000336 239.0
HFD3_k127_2636679_3 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000004465 201.0
HFD3_k127_2636679_4 - - - - 0.000000000000000000000000000000005292 134.0
HFD3_k127_2636679_5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0000000000000000000000000000001963 124.0
HFD3_k127_2636679_6 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000007605 113.0
HFD3_k127_2636679_7 - - - - 0.000000000000000000000000004718 115.0
HFD3_k127_2636679_8 PFAM Single-stranded nucleic acid binding R3H K06346 - - 0.0000000000000000000000002077 111.0
HFD3_k127_2636679_9 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000005077 73.0
HFD3_k127_2660222_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 412.0
HFD3_k127_2660222_1 beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009905 293.0
HFD3_k127_2660222_2 Helix-turn-helix domain - - - 0.00000006154 56.0
HFD3_k127_2677500_0 Carboxypeptidase regulatory-like domain - - - 8.907e-218 715.0
HFD3_k127_2677500_1 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006507 523.0
HFD3_k127_2677500_2 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009697 437.0
HFD3_k127_2677500_3 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000005853 155.0
HFD3_k127_2677500_4 cAMP biosynthetic process - - - 0.0005693 43.0
HFD3_k127_2705422_0 Peptidase M14, carboxypeptidase A - - - 0.0 1498.0
HFD3_k127_2705422_1 Dehydrogenase K00114,K17760,K22473 - 1.1.2.8,1.1.5.5,1.1.9.1 3.63e-263 827.0
HFD3_k127_2705422_2 Glycosyl hydrolase family 9 K01179 - 3.2.1.4 1.069e-211 675.0
HFD3_k127_2705422_3 Sugar (and other) transporter K08178 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000228 284.0
HFD3_k127_2705422_4 - - - - 0.00000001923 62.0
HFD3_k127_2706537_0 peptidase S9B dipeptidylpeptidase IV domain protein - - - 0.0 1079.0
HFD3_k127_2706537_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005898 548.0
HFD3_k127_2706537_2 - - - - 0.0000000000000000000001412 104.0
HFD3_k127_2706537_3 DegT/DnrJ/EryC1/StrS aminotransferase family K12452,K13017 - 1.17.1.1,2.6.1.98 0.00000000000000000001033 96.0
HFD3_k127_2706537_4 DegT/DnrJ/EryC1/StrS aminotransferase family K12452,K13017 - 1.17.1.1,2.6.1.98 0.00000001863 59.0
HFD3_k127_2718741_0 Pfam Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001571 270.0
HFD3_k127_2718741_1 TIGRFAM outer membrane protein assembly complex, YaeT protein K07277 - - 0.00000000000003866 79.0
HFD3_k127_2718741_2 - - - - 0.000004938 59.0
HFD3_k127_2733638_0 Cytochrome C oxidase subunit II, periplasmic domain K00376 - 1.7.2.4 9.47e-304 940.0
HFD3_k127_2733638_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 560.0
HFD3_k127_2733638_10 Cupin 2, conserved barrel domain protein K18991 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009438,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019243,GO:0019249,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046185,GO:0046394,GO:0051596,GO:0061727,GO:0071704,GO:0072330,GO:1901575,GO:1901576,GO:1901615,GO:1901617 - 0.0000000000000000000000000002549 119.0
HFD3_k127_2733638_11 PFAM Formylglycine-generating sulfatase enzyme K18912 - 1.14.99.50 0.0000000000000000000000000006184 127.0
HFD3_k127_2733638_12 NosL K19342 - - 0.00000000000000000000003403 105.0
HFD3_k127_2733638_13 TIGRFAM Transcriptional regulator, Rrf2 - - - 0.00000000000000000004888 95.0
HFD3_k127_2733638_14 cytochrome c - - - 0.000000002439 61.0
HFD3_k127_2733638_15 helix_turn_helix, Lux Regulon K07684 - - 0.00000007464 63.0
HFD3_k127_2733638_2 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004397 476.0
HFD3_k127_2733638_3 TIGRFAM parallel beta-helix repeat (two copies) K07218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 332.0
HFD3_k127_2733638_4 - - - - 0.00000000000000000000000000000000000000000000000000000000003003 221.0
HFD3_k127_2733638_5 lipoprotein involved in nitrous oxide reduction - - - 0.0000000000000000000000000000000000000000000000000000000754 202.0
HFD3_k127_2733638_6 ABC transporter K01990,K19340 - - 0.000000000000000000000000000000000000000000000000000000412 204.0
HFD3_k127_2733638_7 - - - - 0.000000000000000000000000000000000000000000000000000002014 207.0
HFD3_k127_2733638_8 ABC-2 family transporter protein K01992,K19341 - - 0.0000000000000000000000000000000000000000000000001771 186.0
HFD3_k127_2733638_9 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000000000000000000000002743 167.0
HFD3_k127_2756839_0 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 469.0
HFD3_k127_2756839_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004902 341.0
HFD3_k127_2756839_10 membrane protein (homolog of Drosophila rhomboid) K19225 - 3.4.21.105 0.0000000000000000000000000000000000000002712 165.0
HFD3_k127_2756839_11 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000003267 133.0
HFD3_k127_2756839_12 AI-2E family transporter - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000000000000000000000000001083 136.0
HFD3_k127_2756839_13 - - - - 0.000000000003663 67.0
HFD3_k127_2756839_14 Two component signalling adaptor domain K03408 - - 0.0000000009404 66.0
HFD3_k127_2756839_15 - - - - 0.00000005186 58.0
HFD3_k127_2756839_17 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0002179 51.0
HFD3_k127_2756839_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007099 340.0
HFD3_k127_2756839_3 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008576 346.0
HFD3_k127_2756839_4 dTDP biosynthetic process K00560,K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.1.1.45,2.7.4.9,4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 324.0
HFD3_k127_2756839_5 Domain of unknown function (DUF5122) beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005739 302.0
HFD3_k127_2756839_6 dTDP biosynthetic process K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.9,4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000008042 264.0
HFD3_k127_2756839_7 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000178 248.0
HFD3_k127_2756839_8 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000004916 214.0
HFD3_k127_2756839_9 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000002592 197.0
HFD3_k127_2771521_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1382.0
HFD3_k127_2771521_1 Putative glucoamylase - - - 9.288e-246 763.0
HFD3_k127_2771521_10 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 332.0
HFD3_k127_2771521_11 PFAM Prenyltransferase squalene oxidase K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 345.0
HFD3_k127_2771521_12 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000000000001109 190.0
HFD3_k127_2771521_13 Low affinity iron permease - - - 0.000000000000000000000000000000000000000000000005821 177.0
HFD3_k127_2771521_14 Cupin domain - - - 0.000000000000000000000000000000000000000000000006142 174.0
HFD3_k127_2771521_15 acetyltransferase - - - 0.00000000000000000000000000000000000000000000002472 175.0
HFD3_k127_2771521_16 - - - - 0.00000000000000000000000000000000000000000001499 168.0
HFD3_k127_2771521_17 Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000000000000000000000001999 161.0
HFD3_k127_2771521_18 - - - - 0.00000000000000000000000000000006431 132.0
HFD3_k127_2771521_19 Peptidoglycan-binding domain 1 protein K03286,K12543 - - 0.000000000000000000000000000006742 137.0
HFD3_k127_2771521_2 Putative glucoamylase - - - 1.652e-201 635.0
HFD3_k127_2771521_20 - - - - 0.0000000000000000000000000001097 121.0
HFD3_k127_2771521_21 Tyrosine phosphatase family - - - 0.000000000000000000000000009126 118.0
HFD3_k127_2771521_22 Transcriptional regulatory protein, C terminal - - - 0.000000000000000007776 99.0
HFD3_k127_2771521_23 Beta-xylosidase K01198 - 3.2.1.37 0.00000000000000002815 83.0
HFD3_k127_2771521_26 Zinc metalloprotease (Elastase) - - - 0.000000000002939 81.0
HFD3_k127_2771521_27 Belongs to the UPF0337 (CsbD) family - - - 0.00003034 49.0
HFD3_k127_2771521_3 Holliday junction DNA helicase ruvB N-terminus - - - 9.055e-200 646.0
HFD3_k127_2771521_4 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 610.0
HFD3_k127_2771521_5 Aldo/keto reductase family K05275 - 1.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 523.0
HFD3_k127_2771521_6 AAA ATPase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000625 520.0
HFD3_k127_2771521_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 467.0
HFD3_k127_2771521_8 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004932 439.0
HFD3_k127_2771521_9 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 370.0
HFD3_k127_27737_0 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 351.0
HFD3_k127_27737_1 Transcriptional regulator K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 327.0
HFD3_k127_27737_2 Outer membrane efflux protein K15725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002852 259.0
HFD3_k127_2894362_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.0000000000000000000000000000000000000000000000000001453 213.0
HFD3_k127_2894362_1 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000008242 186.0
HFD3_k127_2894362_2 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000000000000000000001008 153.0
HFD3_k127_2894362_3 Prokaryotic N-terminal methylation motif K02456 - - 0.00000000000000000000000001546 115.0
HFD3_k127_2894362_4 Belongs to the GSP D family K02453 - - 0.00000000000000000001305 106.0
HFD3_k127_2894362_5 Tetratricopeptide repeat - - - 0.00000000000000000003355 104.0
HFD3_k127_2894362_6 Belongs to the 'phage' integrase family - - - 0.00000000000000004674 86.0
HFD3_k127_2894362_7 Pilus assembly protein - - - 0.000001543 59.0
HFD3_k127_2895098_0 transport - - - 0.0 1201.0
HFD3_k127_2895098_1 Carboxypeptidase regulatory-like domain - - - 0.0 1031.0
HFD3_k127_2895098_10 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006559 361.0
HFD3_k127_2895098_11 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000123 240.0
HFD3_k127_2895098_12 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000001344 205.0
HFD3_k127_2895098_13 BadF BadG BcrA BcrD K00884,K02616 - 2.7.1.59 0.000000000000000000000000000000000000000008419 167.0
HFD3_k127_2895098_14 SIS domain K00820 - 2.6.1.16 0.00000000000000000000000000000000000312 151.0
HFD3_k127_2895098_15 Transcriptional regulator, LysR family K21703 - - 0.00000000000000000000000000000000000361 149.0
HFD3_k127_2895098_2 beta-lactamase - - - 3.332e-260 828.0
HFD3_k127_2895098_3 IgA Peptidase M64 - - - 1.778e-210 667.0
HFD3_k127_2895098_4 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.934e-197 638.0
HFD3_k127_2895098_5 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006428 608.0
HFD3_k127_2895098_6 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008249 545.0
HFD3_k127_2895098_7 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 546.0
HFD3_k127_2895098_8 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 441.0
HFD3_k127_2895098_9 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 359.0
HFD3_k127_2912216_0 choline dehydrogenase activity - - - 2.768e-306 947.0
HFD3_k127_2912216_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 7.13e-223 712.0
HFD3_k127_2912216_11 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000002145 126.0
HFD3_k127_2912216_12 Hep Hag repeat protein K11904,K21449 - - 0.00000000000000001687 98.0
HFD3_k127_2912216_13 S-layer homology domain - - - 0.000000000000002607 89.0
HFD3_k127_2912216_14 tail collar domain protein - - - 0.00000004952 67.0
HFD3_k127_2912216_15 Calcium/calmodulin dependent protein kinase II association domain - - - 0.000004239 55.0
HFD3_k127_2912216_2 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 7.376e-219 702.0
HFD3_k127_2912216_3 Aldehyde dehydrogenase K22187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 426.0
HFD3_k127_2912216_4 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004606 438.0
HFD3_k127_2912216_5 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 385.0
HFD3_k127_2912216_6 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K01768,K07315 - 3.1.3.3,4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 330.0
HFD3_k127_2912216_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004088 259.0
HFD3_k127_2912216_8 PFAM amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000003472 226.0
HFD3_k127_2912216_9 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000006311 215.0
HFD3_k127_2912261_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 3.52e-222 698.0
HFD3_k127_2912261_1 Phosphotriesterase K07048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 537.0
HFD3_k127_2912261_2 C-terminal, D2-small domain, of ClpB protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 416.0
HFD3_k127_2912261_3 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000001681 250.0
HFD3_k127_2912261_4 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000001154 218.0
HFD3_k127_2912261_5 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000001148 119.0
HFD3_k127_2912261_6 - - - - 0.000000000000000000001828 100.0
HFD3_k127_2917_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1369.0
HFD3_k127_2917_1 Tricorn protease C1 domain K08676 - - 0.0 1259.0
HFD3_k127_2917_10 Proline racemase K01777 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016855,GO:0018112,GO:0019752,GO:0036361,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0047661,GO:0050346,GO:0071704,GO:1901564 5.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 459.0
HFD3_k127_2917_11 e3 binding domain K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 398.0
HFD3_k127_2917_12 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 341.0
HFD3_k127_2917_13 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 331.0
HFD3_k127_2917_14 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004934 347.0
HFD3_k127_2917_15 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007054 316.0
HFD3_k127_2917_16 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002342 290.0
HFD3_k127_2917_17 Predicted Zn-dependent protease (DUF2268) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002657 282.0
HFD3_k127_2917_18 Met-10+ like-protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001436 237.0
HFD3_k127_2917_19 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03644,K03801 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181,2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000002041 234.0
HFD3_k127_2917_2 AcrB/AcrD/AcrF family - - - 0.0 1048.0
HFD3_k127_2917_20 Glycerophosphoryl diester phosphodiesterase family K01113,K01126 - 3.1.3.1,3.1.4.46 0.000000000000000000000000000000000000000000000000000001087 205.0
HFD3_k127_2917_21 COG1024 Enoyl-CoA hydratase carnithine racemase - - - 0.00000000000000000000000000000000000000000000005316 179.0
HFD3_k127_2917_22 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00363,K05710 - 1.7.1.15 0.0000000000000000000000002832 108.0
HFD3_k127_2917_23 - - - - 0.00000000000000000001308 96.0
HFD3_k127_2917_24 Peptidase family M28 - - - 0.0000000000000000152 82.0
HFD3_k127_2917_25 2-aminoethylphosphonate-pyruvate transaminase activity - - - 0.0000000000001521 80.0
HFD3_k127_2917_26 Protein of unknown function (DUF2911) - - - 0.0000009237 59.0
HFD3_k127_2917_3 MacB-like periplasmic core domain - - - 1.902e-247 789.0
HFD3_k127_2917_4 Bacterial protein of unknown function (DUF885) - - - 4.409e-212 676.0
HFD3_k127_2917_5 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 589.0
HFD3_k127_2917_6 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 535.0
HFD3_k127_2917_7 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 526.0
HFD3_k127_2917_8 Melibiase K07407 - 3.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004154 487.0
HFD3_k127_2917_9 Transketolase, pyrimidine binding domain K00167 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 467.0
HFD3_k127_294123_0 cellulose binding - - - 0.0 1157.0
HFD3_k127_294123_1 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 321.0
HFD3_k127_294123_2 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000001146 244.0
HFD3_k127_294123_3 -O-antigen - - - 0.00000000000000000000000000000000000000000000000000106 200.0
HFD3_k127_3007255_0 AAA ATPase, central domain protein K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 496.0
HFD3_k127_3007255_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007918 293.0
HFD3_k127_3007255_2 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004943 253.0
HFD3_k127_3007255_3 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000005494 182.0
HFD3_k127_3007255_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000113 171.0
HFD3_k127_3007255_5 OsmC-like protein K06889,K07397 - - 0.000000000000000000000000000000000000000000007518 169.0
HFD3_k127_3007255_6 lipoprotein localization to outer membrane K02004 - - 0.00000000000000000000000000000000000000000003268 176.0
HFD3_k127_3007255_7 Glucose / Sorbosone dehydrogenase K00428,K01728 - 1.11.1.5,4.2.2.2 0.0000000000000000000003508 113.0
HFD3_k127_3007255_8 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000001437 83.0
HFD3_k127_3007255_9 Molecular chaperone - - - 0.000000000001903 76.0
HFD3_k127_3007721_0 amino acid K03294 - - 3.004e-218 690.0
HFD3_k127_3007721_1 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 460.0
HFD3_k127_3007721_2 COG1078 HD superfamily phosphohydrolases K06885 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007305 309.0
HFD3_k127_3007721_3 LytTr DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001417 262.0
HFD3_k127_3007721_4 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000006343 245.0
HFD3_k127_3007721_5 protein possibly involved in aromatic compounds catabolism - - - 0.00000000000000000000000000000000000000000000002891 173.0
HFD3_k127_3007721_6 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000000000004512 98.0
HFD3_k127_3057448_0 efflux transmembrane transporter activity - - - 3.51e-226 725.0
HFD3_k127_3057448_1 efflux transmembrane transporter activity K02004 - - 1.268e-200 652.0
HFD3_k127_3057448_2 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005796 601.0
HFD3_k127_3057448_3 Tricorn protease C1 domain K08676 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 528.0
HFD3_k127_3057448_4 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 329.0
HFD3_k127_3057448_5 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008409 326.0
HFD3_k127_3057448_6 Beta-lactamase class C and other penicillin binding K01286 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 304.0
HFD3_k127_3057448_7 - - - - 0.000000000000000000000000000000000000000000000000000000001805 206.0
HFD3_k127_3057448_8 protein conserved in cyanobacteria - - - 0.000000000000000000000000000000000000000000000000000000005684 204.0
HFD3_k127_310594_0 Belongs to the GPI family K01810 - 5.3.1.9 2.171e-281 872.0
HFD3_k127_310594_1 Carboxypeptidase regulatory-like domain - - - 1.376e-207 684.0
HFD3_k127_310594_10 Acetyltransferase (GNAT) domain - - - 0.0000000000000001873 88.0
HFD3_k127_310594_11 TIGRFAM TonB K03832 - - 0.000000000000001183 89.0
HFD3_k127_310594_12 - - - - 0.000000000006056 74.0
HFD3_k127_310594_13 ATP-grasp domain - - - 0.0002654 48.0
HFD3_k127_310594_2 Hydroxymethylglutaryl-coenzyme A reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002774 565.0
HFD3_k127_310594_3 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 540.0
HFD3_k127_310594_4 hydroperoxide reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 440.0
HFD3_k127_310594_5 Protein of unknown function (DUF1298) K00635 - 2.3.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 429.0
HFD3_k127_310594_6 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 310.0
HFD3_k127_310594_7 PGAP1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001617 258.0
HFD3_k127_310594_8 - - - - 0.000000000000000000000000000004726 125.0
HFD3_k127_3154254_0 cellulose binding - - - 0.0 1113.0
HFD3_k127_3154254_1 Response regulator receiver - - - 4.468e-203 640.0
HFD3_k127_3154254_10 WD40 repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 359.0
HFD3_k127_3154254_11 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007799 300.0
HFD3_k127_3154254_12 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003377 301.0
HFD3_k127_3154254_13 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840,K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000003301 259.0
HFD3_k127_3154254_14 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000009219 268.0
HFD3_k127_3154254_15 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001303 248.0
HFD3_k127_3154254_16 PFAM Calcineurin-like phosphoesterase K07099 - - 0.000000000000000000000000000000000000000000000000000000000000000004885 233.0
HFD3_k127_3154254_17 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000003254 220.0
HFD3_k127_3154254_18 - - - - 0.00000000000000000000000000000000000000000000000000000000005107 211.0
HFD3_k127_3154254_19 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000002936 203.0
HFD3_k127_3154254_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 562.0
HFD3_k127_3154254_20 - - - - 0.0000000000000000000000000000000000000000000000000000005629 198.0
HFD3_k127_3154254_21 Ribonuclease HII K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000005417 186.0
HFD3_k127_3154254_22 - - - - 0.0000000000000000000000000000000000000000006926 166.0
HFD3_k127_3154254_23 PFAM thiamine monophosphate synthase K00788 - 2.5.1.3 0.000000000000000000000000000000000000443 149.0
HFD3_k127_3154254_24 TIR domain - - - 0.000000000000000000000000000000002118 143.0
HFD3_k127_3154254_25 - - - - 0.0000000000000000000000000004226 118.0
HFD3_k127_3154254_26 PFAM peptidase S16 lon domain protein K07157 - - 0.0000000000000000000006397 105.0
HFD3_k127_3154254_27 DNA-templated transcription, initiation K03088 - - 0.00000000000000000008817 98.0
HFD3_k127_3154254_28 transferase activity, transferring glycosyl groups - - - 0.000000000000004311 88.0
HFD3_k127_3154254_29 - - - - 0.00000000000005262 82.0
HFD3_k127_3154254_3 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 555.0
HFD3_k127_3154254_30 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000006845 74.0
HFD3_k127_3154254_31 O-Antigen ligase - - - 0.00000000008505 75.0
HFD3_k127_3154254_32 protein tyrosine phosphatase activity K01104 - 3.1.3.48 0.0001546 46.0
HFD3_k127_3154254_33 - - - - 0.0007563 48.0
HFD3_k127_3154254_4 Periplasmic protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 518.0
HFD3_k127_3154254_5 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 438.0
HFD3_k127_3154254_6 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 399.0
HFD3_k127_3154254_7 thiamine diphosphate biosynthetic process K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 376.0
HFD3_k127_3154254_8 PFAM ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009003 369.0
HFD3_k127_3154254_9 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004575 362.0
HFD3_k127_3160143_0 TonB-dependent receptor - - - 1.967e-260 839.0
HFD3_k127_3160143_1 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 1.133e-224 707.0
HFD3_k127_3160143_10 Cys/Met metabolism PLP-dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 415.0
HFD3_k127_3160143_11 Trehalose utilisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005656 412.0
HFD3_k127_3160143_12 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02031,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008228 391.0
HFD3_k127_3160143_13 Permease family K06901 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006724 395.0
HFD3_k127_3160143_14 benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 387.0
HFD3_k127_3160143_15 Transmembrane secretion effector K08225 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008815 385.0
HFD3_k127_3160143_16 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 376.0
HFD3_k127_3160143_17 Metal-dependent hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 369.0
HFD3_k127_3160143_18 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 356.0
HFD3_k127_3160143_19 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 359.0
HFD3_k127_3160143_2 TonB-dependent receptor - - - 1.423e-212 701.0
HFD3_k127_3160143_20 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000564 338.0
HFD3_k127_3160143_21 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005966 339.0
HFD3_k127_3160143_22 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007514 331.0
HFD3_k127_3160143_23 KR domain K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 324.0
HFD3_k127_3160143_24 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 315.0
HFD3_k127_3160143_25 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 338.0
HFD3_k127_3160143_26 Domain of unknown function (DUF1731) K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 301.0
HFD3_k127_3160143_27 PFAM transferase hexapeptide repeat containing protein K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 290.0
HFD3_k127_3160143_28 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000424 284.0
HFD3_k127_3160143_29 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001306 289.0
HFD3_k127_3160143_3 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008017 609.0
HFD3_k127_3160143_30 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000007023 266.0
HFD3_k127_3160143_31 Amidinotransferase K01482 - 3.5.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000001724 260.0
HFD3_k127_3160143_32 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000542 272.0
HFD3_k127_3160143_33 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003717 262.0
HFD3_k127_3160143_34 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000001414 243.0
HFD3_k127_3160143_35 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000341 229.0
HFD3_k127_3160143_36 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000141 219.0
HFD3_k127_3160143_37 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000006522 218.0
HFD3_k127_3160143_38 PFAM Neutral alkaline nonlysosomal ceramidase - - - 0.000000000000000000000000000000000000000000000000000000000544 222.0
HFD3_k127_3160143_39 helix_turn_helix, mercury resistance K22491 - - 0.000000000000000000000000000000000000000000000000001187 195.0
HFD3_k127_3160143_4 amino acid transport K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 509.0
HFD3_k127_3160143_40 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.0000000000000000000000000000000000000000000000005636 186.0
HFD3_k127_3160143_41 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000008313 174.0
HFD3_k127_3160143_42 thiolester hydrolase activity K06889 - - 0.0000000000000000000000000000000000000000002345 172.0
HFD3_k127_3160143_43 PFAM Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000002627 169.0
HFD3_k127_3160143_44 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000005139 166.0
HFD3_k127_3160143_45 YhhN family - - - 0.00000000000000000000000000000000000000001492 162.0
HFD3_k127_3160143_46 chaperone-mediated protein folding - - - 0.000000000000000000000000000000000001889 156.0
HFD3_k127_3160143_47 cellular response to heat K09807 - - 0.00000000000000000000000000000000002197 145.0
HFD3_k127_3160143_48 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000001306 129.0
HFD3_k127_3160143_49 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000946 132.0
HFD3_k127_3160143_5 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007427 503.0
HFD3_k127_3160143_50 MFS transporter - - - 0.00000000000000000000000000000009659 138.0
HFD3_k127_3160143_51 PFAM Cyclic nucleotide-binding K10914 - - 0.000000000000000000000000002103 121.0
HFD3_k127_3160143_52 - - - - 0.0000000000000002757 89.0
HFD3_k127_3160143_53 Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000004538 82.0
HFD3_k127_3160143_54 Reeler domain - - - 0.000000000000008989 85.0
HFD3_k127_3160143_55 peptidyl-tyrosine sulfation - - - 0.0000000000826 70.0
HFD3_k127_3160143_56 Glycosyltransferase family 87 K13671 GO:0000026,GO:0000030,GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.000000001498 70.0
HFD3_k127_3160143_57 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.000000002089 69.0
HFD3_k127_3160143_58 Prokaryotic N-terminal methylation motif K02650 - - 0.00000001061 64.0
HFD3_k127_3160143_59 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.0000002986 61.0
HFD3_k127_3160143_6 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 474.0
HFD3_k127_3160143_60 NIPSNAP - - - 0.000007976 48.0
HFD3_k127_3160143_62 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030312,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0007022 50.0
HFD3_k127_3160143_7 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004386 457.0
HFD3_k127_3160143_8 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009645 428.0
HFD3_k127_3160143_9 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 426.0
HFD3_k127_3165655_0 peptidase S9B dipeptidylpeptidase IV domain protein - - - 0.0 1030.0
HFD3_k127_3165655_1 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 390.0
HFD3_k127_3165655_2 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006171 319.0
HFD3_k127_3165655_3 Domain of unknown function (DUF2383) - - - 0.0000000000000000000000000000000000000000005139 166.0
HFD3_k127_3165655_4 - - - - 0.000000000000000000000000000000000000000008795 165.0
HFD3_k127_3165655_5 DinB family - - - 0.000000000000000000000002045 110.0
HFD3_k127_3170311_0 Belongs to the peptidase M16 family K07263 - - 0.0 1133.0
HFD3_k127_3170311_1 transport - - - 1.631e-300 959.0
HFD3_k127_3170311_10 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000000000000007639 234.0
HFD3_k127_3170311_11 Rieske-like [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000000000000000000004723 223.0
HFD3_k127_3170311_12 Protein of unknown function (DUF1223) - - - 0.00000000000000000000000000000000000000000000000000007417 199.0
HFD3_k127_3170311_13 nitrite reductase [NAD(P)H] activity - - - 0.000000000000000000000000000000000000000000000000877 195.0
HFD3_k127_3170311_14 Domain of unknown function (DUF4350) - - - 0.0000000000000000000000000001334 129.0
HFD3_k127_3170311_15 protein conserved in bacteria K04750 - - 0.0000000000000000000000000001977 120.0
HFD3_k127_3170311_16 Domain of unknown function (DUF4440) - - - 0.000000000000000001862 90.0
HFD3_k127_3170311_17 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins K03466 - - 0.00000002362 63.0
HFD3_k127_3170311_18 peptidoglycan binding K02453,K03749 GO:0000910,GO:0003674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0022402,GO:0030428,GO:0032153,GO:0032506,GO:0042834,GO:0044464,GO:0051301,GO:0097367 - 0.00004861 51.0
HFD3_k127_3170311_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 394.0
HFD3_k127_3170311_3 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 368.0
HFD3_k127_3170311_4 Elongator protein 3, MiaB family, Radical SAM K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 344.0
HFD3_k127_3170311_5 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 332.0
HFD3_k127_3170311_6 D-aminopeptidase K16203 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 322.0
HFD3_k127_3170311_7 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009271 244.0
HFD3_k127_3170311_8 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000001035 256.0
HFD3_k127_3170311_9 helix_turn_helix, arabinose operon control protein K07506 - - 0.00000000000000000000000000000000000000000000000000000000000000000001109 246.0
HFD3_k127_3183718_0 Beta galactosidase small chain K01190 - 3.2.1.23 0.0 1366.0
HFD3_k127_3183718_1 Prolyl oligopeptidase family K01303 - 3.4.19.1 5.272e-220 703.0
HFD3_k127_3183718_10 Multicopper oxidase K06324 - 1.16.3.3 0.000000000000000000000000000000000514 135.0
HFD3_k127_3183718_11 Protein of unknown function (DUF4242) - - - 0.0000000000000000007895 88.0
HFD3_k127_3183718_12 - - - - 0.000000000000003805 79.0
HFD3_k127_3183718_13 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000003804 77.0
HFD3_k127_3183718_14 - - - - 0.0000000002651 66.0
HFD3_k127_3183718_15 typically periplasmic contain C-terminal PDZ domain K04771 - 3.4.21.107 0.000007814 57.0
HFD3_k127_3183718_16 transposase activity - - - 0.0001088 51.0
HFD3_k127_3183718_2 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 607.0
HFD3_k127_3183718_3 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 449.0
HFD3_k127_3183718_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006189 312.0
HFD3_k127_3183718_5 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008309 284.0
HFD3_k127_3183718_6 regulatory protein TetR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003081 245.0
HFD3_k127_3183718_7 PFAM OsmC family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001119 241.0
HFD3_k127_3183718_8 - - - - 0.00000000000000000000000000000000003324 142.0
HFD3_k127_3183718_9 - - - - 0.00000000000000000000000000000000005338 139.0
HFD3_k127_3188810_0 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 1.652e-317 994.0
HFD3_k127_3188810_1 Dienelactone hydrolase family - - - 3.284e-271 858.0
HFD3_k127_3188810_10 CO dehydrogenase flavoprotein C-terminal domain K13479 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000002217 230.0
HFD3_k127_3188810_11 TipAS antibiotic-recognition domain - - - 0.000000000000000000000000000000000000000000000000000000000000001198 227.0
HFD3_k127_3188810_12 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000547 214.0
HFD3_k127_3188810_13 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000000000000832 209.0
HFD3_k127_3188810_14 PFAM Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000001257 208.0
HFD3_k127_3188810_15 Membrane - - - 0.0000000000000000000000000000000000000000000000000006797 209.0
HFD3_k127_3188810_16 - - - - 0.00000000000000000000000000000000000002698 147.0
HFD3_k127_3188810_17 Cupredoxin-like domain K02275 - 1.9.3.1 0.00000000000000000000000000000002683 129.0
HFD3_k127_3188810_18 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.0000000000000000000000000000002125 136.0
HFD3_k127_3188810_19 Rhodanese Homology Domain - - - 0.0000000000000000000000000000002653 130.0
HFD3_k127_3188810_2 Carboxypeptidase regulatory-like domain - - - 1.013e-260 827.0
HFD3_k127_3188810_20 Tetratricopeptide repeat - - - 0.0000000000000000000000000000007668 131.0
HFD3_k127_3188810_21 - - - - 0.000000000000000000000000000006072 121.0
HFD3_k127_3188810_22 RNA recognition motif - - - 0.0000000000000000000000000002296 118.0
HFD3_k127_3188810_23 - - - - 0.000000000000000001727 94.0
HFD3_k127_3188810_24 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000000002424 91.0
HFD3_k127_3188810_25 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000011 83.0
HFD3_k127_3188810_26 - - - - 0.000000000000008507 76.0
HFD3_k127_3188810_27 - - - - 0.0000000000002517 74.0
HFD3_k127_3188810_28 Protein of unknown function (DUF3108) - - - 0.0000000000004895 79.0
HFD3_k127_3188810_29 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0003067 53.0
HFD3_k127_3188810_3 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding - - - 2.094e-227 727.0
HFD3_k127_3188810_4 tetratricopeptide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 597.0
HFD3_k127_3188810_5 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006816 499.0
HFD3_k127_3188810_6 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 482.0
HFD3_k127_3188810_7 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 406.0
HFD3_k127_3188810_8 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003216 295.0
HFD3_k127_3188810_9 AntiSigma factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003173 271.0
HFD3_k127_3192510_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0 3126.0
HFD3_k127_3192510_1 Dehydrogenase E1 component K11381 - 1.2.4.4 2.234e-289 905.0
HFD3_k127_3192510_10 RNA recognition motif - - - 0.00000000000000000003019 93.0
HFD3_k127_3192510_11 PFAM Transcription factor CarD K07736 - - 0.00000000005233 70.0
HFD3_k127_3192510_12 - - - - 0.000000000218 70.0
HFD3_k127_3192510_13 Transposase IS200 like K07491 - - 0.00004567 47.0
HFD3_k127_3192510_2 3-isopropylmalate dehydratase activity K01681,K01703,K01704,K17749 - 4.2.1.3,4.2.1.33,4.2.1.35 7.026e-233 738.0
HFD3_k127_3192510_3 Acyl-CoA dehydrogenase, C-terminal domain K00248,K09478 - 1.3.8.1,1.3.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 569.0
HFD3_k127_3192510_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 519.0
HFD3_k127_3192510_5 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006432 347.0
HFD3_k127_3192510_6 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 319.0
HFD3_k127_3192510_7 PFAM CheR methyltransferase, SAM binding domain K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 304.0
HFD3_k127_3192510_8 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000199 240.0
HFD3_k127_3192510_9 Transposase K07491 - - 0.0000000000000000000000000000000000000000000003165 173.0
HFD3_k127_3212306_0 MacB-like periplasmic core domain - - - 1.056e-211 683.0
HFD3_k127_3212306_1 Transcriptional regulator PadR-like family - - - 0.000000000000008515 75.0
HFD3_k127_3215412_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00700 - 2.4.1.18 7.69e-230 730.0
HFD3_k127_3215412_1 Flavin containing amine oxidoreductase - - - 1.207e-213 677.0
HFD3_k127_3215412_10 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K10907 - - 0.000000000000000000000000000000000000000000000000000000000000001707 236.0
HFD3_k127_3215412_11 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000001774 231.0
HFD3_k127_3215412_12 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000003204 225.0
HFD3_k127_3215412_13 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000000009513 201.0
HFD3_k127_3215412_14 Isochorismatase family K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000001123 189.0
HFD3_k127_3215412_15 Membrane - - - 0.0000000000000000000000000000000000000000000000001373 186.0
HFD3_k127_3215412_16 CoA binding domain K06929 - - 0.000000000000000000000000000000000000001424 153.0
HFD3_k127_3215412_17 Amino-transferase class IV K00826 - 2.6.1.42 0.00000000000000000000000000000000000002522 154.0
HFD3_k127_3215412_18 PFAM thioesterase superfamily K07107 - - 0.00000000000000000000000000000000001905 147.0
HFD3_k127_3215412_19 Redoxin - - - 0.000000000000000000000000000000002486 146.0
HFD3_k127_3215412_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.471e-207 662.0
HFD3_k127_3215412_20 outer membrane autotransporter barrel domain protein - - - 0.000000000000000000000000000000003487 138.0
HFD3_k127_3215412_21 PFAM Uncharacterised protein family UPF0150 K18843 - - 0.000000000000000000000000007485 111.0
HFD3_k127_3215412_22 Protein of unknown function (DUF1572) - - - 0.00000000000000000000000001987 115.0
HFD3_k127_3215412_23 HicA toxin of bacterial toxin-antitoxin, K07339 - - 0.000000000000000000006109 94.0
HFD3_k127_3215412_24 domain protein K14194 - - 0.00000000000000003658 96.0
HFD3_k127_3215412_26 domain protein K14194 - - 0.0000000000203 77.0
HFD3_k127_3215412_27 Transcriptional regulator - - - 0.00000000005471 70.0
HFD3_k127_3215412_28 DNA polymerase Ligase (LigD) - - - 0.00000002969 55.0
HFD3_k127_3215412_3 Aldo/keto reductase family K19265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007479 514.0
HFD3_k127_3215412_4 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 426.0
HFD3_k127_3215412_5 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009086 429.0
HFD3_k127_3215412_6 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 421.0
HFD3_k127_3215412_7 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007366 335.0
HFD3_k127_3215412_8 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 315.0
HFD3_k127_3215412_9 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000008145 241.0
HFD3_k127_3236841_0 Radical SAM - - - 0.0 1213.0
HFD3_k127_3236841_1 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 6.768e-287 888.0
HFD3_k127_3236841_10 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009748 448.0
HFD3_k127_3236841_11 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 389.0
HFD3_k127_3236841_12 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 393.0
HFD3_k127_3236841_13 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 367.0
HFD3_k127_3236841_14 Protein of unknown function (DUF3500) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008257 358.0
HFD3_k127_3236841_15 Belongs to the CinA family K03742 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 353.0
HFD3_k127_3236841_16 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 330.0
HFD3_k127_3236841_17 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 321.0
HFD3_k127_3236841_18 Dual specificity phosphatase, catalytic domain K01090 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006336 326.0
HFD3_k127_3236841_19 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 307.0
HFD3_k127_3236841_2 Sigma-70 region 2 K03088 - - 4.67e-226 708.0
HFD3_k127_3236841_20 PFAM bifunctional deaminase-reductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005172 283.0
HFD3_k127_3236841_21 PFAM RibD C-terminal domain K00287 - 1.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001266 280.0
HFD3_k127_3236841_22 dihydrofolate reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004839 273.0
HFD3_k127_3236841_23 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004102 269.0
HFD3_k127_3236841_24 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000136 267.0
HFD3_k127_3236841_25 PFAM KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000009015 263.0
HFD3_k127_3236841_26 Di-haem oxidoreductase, putative peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002001 271.0
HFD3_k127_3236841_27 glyoxalase III activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000001575 235.0
HFD3_k127_3236841_28 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002558 228.0
HFD3_k127_3236841_29 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000000000000000000009017 220.0
HFD3_k127_3236841_3 (ABC) transporter K06147,K18890 - - 5.506e-202 646.0
HFD3_k127_3236841_30 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000002866 219.0
HFD3_k127_3236841_31 Protein of unknown function (DUF1697) - - - 0.00000000000000000000000000000000000000000000000000000000006306 211.0
HFD3_k127_3236841_32 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000002696 215.0
HFD3_k127_3236841_33 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000002124 186.0
HFD3_k127_3236841_34 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000007315 189.0
HFD3_k127_3236841_35 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000002101 191.0
HFD3_k127_3236841_36 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000002758 175.0
HFD3_k127_3236841_37 Acyl-transferase - - - 0.00000000000000000000000000000000000000005253 162.0
HFD3_k127_3236841_4 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005322 608.0
HFD3_k127_3236841_40 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000003894 125.0
HFD3_k127_3236841_41 ATPase or kinase K06925 GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000000000001904 119.0
HFD3_k127_3236841_42 PFAM Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.000000000000000000000000004146 117.0
HFD3_k127_3236841_43 SCO1/SenC - - - 0.00000000000000000000000005516 122.0
HFD3_k127_3236841_44 Domain of unknown function (DUF4442) K02614 - - 0.000000000000000000000001495 110.0
HFD3_k127_3236841_45 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567,K07443 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 2.1.1.63 0.0000000000000000000002766 104.0
HFD3_k127_3236841_46 Glyoxalase-like domain - - - 0.000000000000000000008616 96.0
HFD3_k127_3236841_47 Rifampin ADP-ribosyl transferase K19062 - - 0.0000000000000211 77.0
HFD3_k127_3236841_48 DinB family - - - 0.00000000000006017 78.0
HFD3_k127_3236841_49 Rifampin ADP-ribosyl transferase - - - 0.0000000000000855 74.0
HFD3_k127_3236841_5 ABC transporter, transmembrane K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 592.0
HFD3_k127_3236841_50 SNARE associated Golgi protein - - - 0.0000000000001589 76.0
HFD3_k127_3236841_51 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.0000000000007391 79.0
HFD3_k127_3236841_52 D-galactarate dehydratase / Altronate hydrolase, C terminus - - - 0.00000001284 57.0
HFD3_k127_3236841_53 - - - - 0.000005754 49.0
HFD3_k127_3236841_54 transcriptional regulator, SARP family - - - 0.000008814 58.0
HFD3_k127_3236841_55 Sporulation related domain K03749 - - 0.0001567 53.0
HFD3_k127_3236841_56 reductase - - - 0.0002263 45.0
HFD3_k127_3236841_7 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000845 487.0
HFD3_k127_3236841_8 beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004475 478.0
HFD3_k127_3236841_9 Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 470.0
HFD3_k127_323865_0 Peptidase M14, carboxypeptidase A - - - 0.0 1117.0
HFD3_k127_323865_1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K00311 - 1.5.5.1 7.92e-207 657.0
HFD3_k127_323865_10 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007383 409.0
HFD3_k127_323865_11 May be involved in the transport of PQQ or its precursor to the periplasm - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 409.0
HFD3_k127_323865_12 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005034 413.0
HFD3_k127_323865_13 Ethanolamine ammonia-lyase light chain (EutC) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006717 419.0
HFD3_k127_323865_14 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 410.0
HFD3_k127_323865_15 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 385.0
HFD3_k127_323865_16 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 375.0
HFD3_k127_323865_17 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 374.0
HFD3_k127_323865_18 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 346.0
HFD3_k127_323865_19 Acyl transferase domain K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008795 342.0
HFD3_k127_323865_2 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 605.0
HFD3_k127_323865_20 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 334.0
HFD3_k127_323865_21 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006597 321.0
HFD3_k127_323865_22 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008674 309.0
HFD3_k127_323865_23 Electron transfer flavoprotein domain K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 298.0
HFD3_k127_323865_24 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 303.0
HFD3_k127_323865_25 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002647 272.0
HFD3_k127_323865_26 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002394 284.0
HFD3_k127_323865_27 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000004521 223.0
HFD3_k127_323865_28 methyltransferase K04786 - - 0.0000000000000000000000000000000000000000000000000000000001339 213.0
HFD3_k127_323865_29 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000003602 207.0
HFD3_k127_323865_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003857 574.0
HFD3_k127_323865_30 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000223 185.0
HFD3_k127_323865_31 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000003396 192.0
HFD3_k127_323865_32 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000004462 164.0
HFD3_k127_323865_33 - - - - 0.00000000000000000000000000000000000000001115 171.0
HFD3_k127_323865_34 dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000002938 172.0
HFD3_k127_323865_35 Bacterial regulatory proteins, tetR family K09017 - - 0.000000000000000000000000000000000002114 147.0
HFD3_k127_323865_36 PFAM 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000001623 139.0
HFD3_k127_323865_37 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000009334 137.0
HFD3_k127_323865_38 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000007486 135.0
HFD3_k127_323865_39 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000001946 123.0
HFD3_k127_323865_4 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 576.0
HFD3_k127_323865_40 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000003515 115.0
HFD3_k127_323865_41 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.0000000000000000000008115 111.0
HFD3_k127_323865_42 response regulator receiver K03407 - 2.7.13.3 0.000000000000000000004498 98.0
HFD3_k127_323865_43 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000001464 89.0
HFD3_k127_323865_44 Belongs to the peptidase S1C family K04771,K04772,K08070 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0031224,GO:0031226,GO:0031233,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051603,GO:0070011,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575 1.3.1.74,3.4.21.107 0.00000000000002683 86.0
HFD3_k127_323865_45 peptidase M15B and M15C DD-carboxypeptidase VanY - - - 0.0000000000001634 80.0
HFD3_k127_323865_46 Domain of unknown function (DUF4149) - - - 0.0000000000002796 77.0
HFD3_k127_323865_5 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 578.0
HFD3_k127_323865_6 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K01710,K02377 - 1.1.1.271,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004513 544.0
HFD3_k127_323865_7 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 559.0
HFD3_k127_323865_8 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006906 482.0
HFD3_k127_323865_9 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004749 446.0
HFD3_k127_3310947_0 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 503.0
HFD3_k127_3310947_1 Mur ligase middle domain K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 463.0
HFD3_k127_3310947_10 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000002641 103.0
HFD3_k127_3310947_11 Protein of unknown function (DUF1232) - - - 0.0000000000000000000000311 105.0
HFD3_k127_3310947_12 XdhC and CoxI family K07402 - - 0.000000000000000000001072 98.0
HFD3_k127_3310947_13 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000000000007703 81.0
HFD3_k127_3310947_14 Universal stress protein family - - - 0.0000000000002313 81.0
HFD3_k127_3310947_15 ABC-type multidrug transport system ATPase component - - - 0.0000000000003385 84.0
HFD3_k127_3310947_16 PFAM S-layer domain protein - - - 0.000000000001984 80.0
HFD3_k127_3310947_17 Protein of unknown function (DUF3616) - - - 0.00000002104 68.0
HFD3_k127_3310947_18 Belongs to the peptidase M10A family K01388,K01394,K01396,K01402,K01413,K07763,K07994,K07999 GO:0000122,GO:0001047,GO:0001067,GO:0001666,GO:0001817,GO:0001819,GO:0001959,GO:0001960,GO:0001961,GO:0002009,GO:0002011,GO:0002682,GO:0002683,GO:0002684,GO:0002697,GO:0002791,GO:0002793,GO:0002831,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004175,GO:0004222,GO:0004252,GO:0005488,GO:0005509,GO:0005518,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006355,GO:0006357,GO:0006508,GO:0006606,GO:0006807,GO:0006810,GO:0006886,GO:0006913,GO:0006928,GO:0006950,GO:0008104,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008237,GO:0008270,GO:0008284,GO:0009056,GO:0009605,GO:0009607,GO:0009611,GO:0009615,GO:0009628,GO:0009653,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010646,GO:0010647,GO:0010648,GO:0014070,GO:0015031,GO:0015833,GO:0016043,GO:0016477,GO:0016787,GO:0017038,GO:0017171,GO:0019219,GO:0019222,GO:0019538,GO:0022411,GO:0022617,GO:0023051,GO:0023056,GO:0023057,GO:0030198,GO:0030334,GO:0030574,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031347,GO:0031348,GO:0031349,GO:0032101,GO:0032479,GO:0032481,GO:0032502,GO:0032647,GO:0032727,GO:0032879,GO:0032880,GO:0032963,GO:0033036,GO:0033365,GO:0034504,GO:0034613,GO:0035313,GO:0036293,GO:0040011,GO:0040012,GO:0042060,GO:0042127,GO:0042221,GO:0042493,GO:0042886,GO:0043062,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043565,GO:0043900,GO:0044212,GO:0044238,GO:0044319,GO:0044421,GO:0044424,GO:0044464,GO:0044877,GO:0045088,GO:0045089,GO:0045184,GO:0045824,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045944,GO:0046872,GO:0046907,GO:0046914,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0048729,GO:0048856,GO:0048870,GO:0050678,GO:0050679,GO:0050688,GO:0050691,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050776,GO:0050777,GO:0050778,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051169,GO:0051170,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051240,GO:0051252,GO:0051253,GO:0051254,GO:0051270,GO:0051641,GO:0051649,GO:0051674,GO:0051704,GO:0051707,GO:0060054,GO:0060255,GO:0060338,GO:0060339,GO:0060340,GO:0060429,GO:0060759,GO:0060760,GO:0060761,GO:0065007,GO:0070011,GO:0070201,GO:0070482,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0080090,GO:0080134,GO:0090087,GO:0090504,GO:0090505,GO:0097159,GO:0098586,GO:0140096,GO:1901163,GO:1901363,GO:1901564,GO:1902679,GO:1902680,GO:1902739,GO:1902741,GO:1903506,GO:1903507,GO:1903508,GO:1903530,GO:1903532,GO:1904951,GO:2000026,GO:2000112,GO:2000113,GO:2000145,GO:2000241,GO:2001141 3.4.24.17,3.4.24.22,3.4.24.34,3.4.24.65,3.4.24.7,3.4.24.80 0.000002845 60.0
HFD3_k127_3310947_2 Multi-sensor signal transduction histidine kinase K07710 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 331.0
HFD3_k127_3310947_3 COG1063 Threonine dehydrogenase and related Zn-dependent K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 315.0
HFD3_k127_3310947_4 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000001388 238.0
HFD3_k127_3310947_5 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000023 248.0
HFD3_k127_3310947_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000002556 221.0
HFD3_k127_3310947_7 Protein of unknown function (DUF2723) - - - 0.000000000000000000000000000000000000000000000000000000000006422 233.0
HFD3_k127_3310947_8 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000007249 170.0
HFD3_k127_3310947_9 - - - - 0.00000000000000000000000000001527 128.0
HFD3_k127_3354884_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 6.708e-318 987.0
HFD3_k127_3354884_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 2.307e-247 776.0
HFD3_k127_3354884_10 Cold shock protein K03704 - - 0.0000000000000000000000004633 105.0
HFD3_k127_3354884_11 domain, Protein - - - 0.00007403 48.0
HFD3_k127_3354884_2 Amino acid permease - - - 8.869e-236 753.0
HFD3_k127_3354884_3 Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005948 469.0
HFD3_k127_3354884_4 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 441.0
HFD3_k127_3354884_5 protein histidine kinase activity K11383 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006137 413.0
HFD3_k127_3354884_7 Histidine kinase K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 310.0
HFD3_k127_3354884_8 response regulator, receiver K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000255 282.0
HFD3_k127_3354884_9 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000005565 243.0
HFD3_k127_3364533_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 8.464e-237 741.0
HFD3_k127_3364533_1 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009045 574.0
HFD3_k127_3364533_10 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000001692 189.0
HFD3_k127_3364533_11 - - - - 0.00000000000000000000000000000000000000000003645 171.0
HFD3_k127_3364533_12 protein phosphatase 2C domain protein K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000005362 168.0
HFD3_k127_3364533_13 MarR family transcriptional regulator - - - 0.00000000000000000000000000000000000002834 147.0
HFD3_k127_3364533_14 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000003549 144.0
HFD3_k127_3364533_15 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000008627 130.0
HFD3_k127_3364533_16 - - - - 0.0000000000000000000000002772 111.0
HFD3_k127_3364533_17 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000007559 103.0
HFD3_k127_3364533_18 RDD family - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000003097 100.0
HFD3_k127_3364533_2 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006503 548.0
HFD3_k127_3364533_20 - - - - 0.0000000000001811 75.0
HFD3_k127_3364533_21 PEGA domain - - - 0.000003515 57.0
HFD3_k127_3364533_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 485.0
HFD3_k127_3364533_4 Amidohydrolase family K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 480.0
HFD3_k127_3364533_5 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 325.0
HFD3_k127_3364533_6 Cellulose biosynthesis protein BcsQ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009807 305.0
HFD3_k127_3364533_7 PFAM ParB domain protein nuclease K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000002917 230.0
HFD3_k127_3364533_8 PFAM Response regulator receiver domain K02483,K18344 - - 0.00000000000000000000000000000000000000000000000000000766 197.0
HFD3_k127_3364533_9 Phosphohydrolase - - - 0.0000000000000000000000000000000000000000000000000005882 193.0
HFD3_k127_3404984_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1052.0
HFD3_k127_3404984_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 446.0
HFD3_k127_3404984_10 PFAM Fimbrial assembly family protein K02663 - - 0.0002819 51.0
HFD3_k127_3404984_2 Di-haem oxidoreductase, putative peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006751 411.0
HFD3_k127_3404984_3 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004434 329.0
HFD3_k127_3404984_4 Type II and III secretion system protein K02666 - - 0.0000000000000000000000000000000000000000000232 186.0
HFD3_k127_3404984_5 - - - - 0.000000000000000000000000000002097 134.0
HFD3_k127_3404984_6 Roadblock/LC7 domain - - - 0.0000000000002219 75.0
HFD3_k127_3404984_7 Pilus assembly protein, PilO K02664 - - 0.00000001942 64.0
HFD3_k127_3404984_8 PFAM TonB-dependent Receptor Plug - - - 0.0000001674 62.0
HFD3_k127_3404984_9 AMIN domain K01448 - 3.5.1.28 0.0001244 56.0
HFD3_k127_3428347_0 SMART Elongator protein 3 MiaB NifB - - - 4.973e-231 751.0
HFD3_k127_3428347_1 COGs COG1132 ABC-type multidrug transport system ATPase and permease components K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 606.0
HFD3_k127_3428347_10 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000001117 241.0
HFD3_k127_3428347_11 TonB-dependent Receptor Plug Domain K02014,K16092 - - 0.0000000000000000000000000000000000000000000000000000000000007376 231.0
HFD3_k127_3428347_12 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000008615 178.0
HFD3_k127_3428347_13 COG0346 Lactoylglutathione lyase and related lyases K05606 - 5.1.99.1 0.0000000000000000000000000000000000000001089 154.0
HFD3_k127_3428347_14 Rod shape-determining protein MreC K03570 - - 0.00000000000000000000000000000000000002964 154.0
HFD3_k127_3428347_15 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000000000000000000001872 132.0
HFD3_k127_3428347_16 LAO AO transport system K07588 - - 0.000000000000000000000000006638 114.0
HFD3_k127_3428347_17 shape-determining protein MreD K03571 - - 0.0000000004903 67.0
HFD3_k127_3428347_19 Putative peptidoglycan binding domain - - - 0.00000001317 64.0
HFD3_k127_3428347_2 cell shape determining protein MreB K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 524.0
HFD3_k127_3428347_20 Outer membrane lipoprotein K05807,K08309 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.00000003199 62.0
HFD3_k127_3428347_3 Ribonuclease, Rne Rng family K08301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006483 542.0
HFD3_k127_3428347_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 485.0
HFD3_k127_3428347_5 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007022 392.0
HFD3_k127_3428347_6 PFAM PfkB domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 374.0
HFD3_k127_3428347_7 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008961 385.0
HFD3_k127_3428347_8 PFAM Metallophosphoesterase K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 298.0
HFD3_k127_3428347_9 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000001504 250.0
HFD3_k127_3470127_0 Domain of unknown function (DUF5117) - - - 0.0 1021.0
HFD3_k127_3470127_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.364e-266 841.0
HFD3_k127_3470127_10 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004607 317.0
HFD3_k127_3470127_11 YdjC-like protein K03478 - 3.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 294.0
HFD3_k127_3470127_12 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006211 251.0
HFD3_k127_3470127_13 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000003457 221.0
HFD3_k127_3470127_14 DNA-templated transcription, initiation - - - 0.000000000000000000000000000000000000000000000000009305 195.0
HFD3_k127_3470127_15 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000007447 174.0
HFD3_k127_3470127_16 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000002703 171.0
HFD3_k127_3470127_17 COGs COG4636 conserved - - - 0.00000000000000000000000000000000000000000006932 166.0
HFD3_k127_3470127_18 FG-GAP repeat - - - 0.0000000000000000000000000000000000000000005113 178.0
HFD3_k127_3470127_19 spore germination - - - 0.000000000000000000000000000000000000008512 149.0
HFD3_k127_3470127_2 SMART Elongator protein 3 MiaB NifB - - - 3.793e-223 700.0
HFD3_k127_3470127_20 membrane K08978 - - 0.000000000000000000000000000004316 123.0
HFD3_k127_3470127_21 GDP-mannose mannosyl hydrolase activity K00974,K03574,K18445 - 2.7.7.72,3.6.1.55,3.6.1.61 0.0000000000000000000000000001784 119.0
HFD3_k127_3470127_22 - - - - 0.000000000000000000000000001936 125.0
HFD3_k127_3470127_23 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000584 102.0
HFD3_k127_3470127_24 regulation of DNA repair K03565 GO:0003674,GO:0005575,GO:0005623,GO:0005886,GO:0006282,GO:0008150,GO:0016020,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0044464,GO:0048583,GO:0050789,GO:0050790,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0098772,GO:2001020 - 0.0000000264 63.0
HFD3_k127_3470127_25 - - - - 0.000001582 49.0
HFD3_k127_3470127_27 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.0001883 53.0
HFD3_k127_3470127_3 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 548.0
HFD3_k127_3470127_4 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 499.0
HFD3_k127_3470127_5 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006239 418.0
HFD3_k127_3470127_6 PFAM Glycosyl transferase family 2 K00720 - 2.4.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 389.0
HFD3_k127_3470127_7 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009052 361.0
HFD3_k127_3470127_8 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 334.0
HFD3_k127_3470127_9 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 340.0
HFD3_k127_3497932_0 Large extracellular alpha-helical protein K06894 - - 0.0 1441.0
HFD3_k127_3497932_1 lipopolysaccharide transport K22110 - - 0.0 1437.0
HFD3_k127_3497932_10 Peptidase S1 and S6 chymotrypsin Hap - - - 0.000000000000000000000000000000000000000000000000001908 191.0
HFD3_k127_3497932_11 Yhs domain-containing protein - - - 0.00000000000000000000000000000000000000000000000001592 184.0
HFD3_k127_3497932_12 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000000000000004064 190.0
HFD3_k127_3497932_2 Sortilin, neurotensin receptor 3, - - - 0.0 1134.0
HFD3_k127_3497932_3 choline dehydrogenase activity - - - 3.011e-273 847.0
HFD3_k127_3497932_4 alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005718 549.0
HFD3_k127_3497932_5 Glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008914 502.0
HFD3_k127_3497932_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005005 458.0
HFD3_k127_3497932_7 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 352.0
HFD3_k127_3497932_8 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 311.0
HFD3_k127_3497932_9 chlorophyll binding - - - 0.00000000000000000000000000000000000000000000000000000000000007719 224.0
HFD3_k127_3691040_0 histidine kinase A domain protein - - - 3.911e-222 726.0
HFD3_k127_3691040_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 2.585e-206 672.0
HFD3_k127_3691040_10 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133,K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0030312,GO:0036094,GO:0040007,GO:0043891,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071944,GO:0097159,GO:1901265,GO:1901363 1.2.1.11,1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 423.0
HFD3_k127_3691040_11 Methane oxygenase PmoA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 411.0
HFD3_k127_3691040_12 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 372.0
HFD3_k127_3691040_13 Arylsulfatase a K01133 - 3.1.6.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007601 376.0
HFD3_k127_3691040_14 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004614 366.0
HFD3_k127_3691040_15 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005997 342.0
HFD3_k127_3691040_16 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005761 324.0
HFD3_k127_3691040_17 peptidase dimerisation domain K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008951 321.0
HFD3_k127_3691040_18 Periplasmic binding protein domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005504 309.0
HFD3_k127_3691040_19 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 317.0
HFD3_k127_3691040_2 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 612.0
HFD3_k127_3691040_20 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 291.0
HFD3_k127_3691040_21 myo-inosose-2 dehydratase activity K03335,K15652 - 4.2.1.118,4.2.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000001272 273.0
HFD3_k127_3691040_22 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001606 271.0
HFD3_k127_3691040_23 G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005542 265.0
HFD3_k127_3691040_24 Copper binding periplasmic protein CusF K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000008671 244.0
HFD3_k127_3691040_25 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000000000000000000006331 223.0
HFD3_k127_3691040_26 Psort location Cytoplasmic, score 8.87 - - - 0.0000000000000000000000000000000000000000000000000000000000001663 228.0
HFD3_k127_3691040_27 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.00000000000000000000000000000000000000000000000000000001984 200.0
HFD3_k127_3691040_28 thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.00000000000000000000000000000000000000000000000000000007101 201.0
HFD3_k127_3691040_29 Protein conserved in bacteria K07011 - - 0.0000000000000000000000000000000000000000000000000000003078 199.0
HFD3_k127_3691040_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 582.0
HFD3_k127_3691040_30 Belongs to the DapB family K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000003294 201.0
HFD3_k127_3691040_31 photosynthesis - - - 0.000000000000000000000000000000000000000000000000000009223 195.0
HFD3_k127_3691040_32 - - - - 0.00000000000000000000000000000000000000000000000003999 188.0
HFD3_k127_3691040_33 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000005257 169.0
HFD3_k127_3691040_34 Protein of unknown function (DUF4242) - - - 0.000000000000000000000000000000000000000000155 160.0
HFD3_k127_3691040_35 transglycosylase associated protein - - - 0.0000000000000000002669 90.0
HFD3_k127_3691040_36 Putative transmembrane protein (PGPGW) - - - 0.00000000000001364 78.0
HFD3_k127_3691040_37 Periplasmic or secreted lipoprotein - - - 0.000003478 59.0
HFD3_k127_3691040_4 PFAM Major Facilitator Superfamily K08191 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000912 545.0
HFD3_k127_3691040_5 Alpha-L-fucosidase K01206 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 490.0
HFD3_k127_3691040_6 OmpA family K02557,K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006519 487.0
HFD3_k127_3691040_7 Belongs to the serpin family K13963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 467.0
HFD3_k127_3691040_8 carbohydrate transport K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 447.0
HFD3_k127_3691040_9 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008144,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015399,GO:0015405,GO:0015407,GO:0015591,GO:0015608,GO:0015611,GO:0015749,GO:0015750,GO:0015752,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034219,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043211,GO:0043492,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 436.0
HFD3_k127_3704008_0 metallocarboxypeptidase activity K14054 - - 0.0 1199.0
HFD3_k127_3704008_1 peptidase S9 prolyl oligopeptidase active site K01303 - 3.4.19.1 4.836e-314 974.0
HFD3_k127_3704008_2 enzyme related to lactoylglutathione lyase K06996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005492 249.0
HFD3_k127_3704008_3 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000000000000000000009344 217.0
HFD3_k127_3704008_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000008682 192.0
HFD3_k127_3704008_5 - - - - 0.000000000000003352 81.0
HFD3_k127_3704008_6 transcription factor binding K15836 - - 0.0000004986 51.0
HFD3_k127_3707306_0 domain protein - - - 0.0 1154.0
HFD3_k127_3707306_1 Cytochrome c554 and c-prime - - - 2.643e-265 840.0
HFD3_k127_3707306_10 Short repeat of unknown function (DUF308) - - - 0.000000000000000000000000000000000000000000000000297 182.0
HFD3_k127_3707306_11 - - - - 0.000000000000000000000000000000000000000001485 158.0
HFD3_k127_3707306_12 - - - - 0.000000000000000000000000000000000008032 141.0
HFD3_k127_3707306_13 hydroperoxide reductase activity K01607 - 4.1.1.44 0.000000000000000000000000000000001326 131.0
HFD3_k127_3707306_14 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000321 93.0
HFD3_k127_3707306_15 Protein of unknown function (DUF3179) - - - 0.00000000006317 70.0
HFD3_k127_3707306_2 Cytochrome c - - - 5.496e-205 646.0
HFD3_k127_3707306_3 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 639.0
HFD3_k127_3707306_4 Reductase C-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 576.0
HFD3_k127_3707306_5 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006626 572.0
HFD3_k127_3707306_6 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 449.0
HFD3_k127_3707306_7 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 409.0
HFD3_k127_3707306_8 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000004611 241.0
HFD3_k127_3707306_9 Protein of unknown function (DUF3179) - - - 0.0000000000000000000000000000000000000000000000001561 184.0
HFD3_k127_3742522_0 GAF domain - - - 1.302e-247 807.0
HFD3_k127_3742522_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 2.188e-226 711.0
HFD3_k127_3742522_10 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 336.0
HFD3_k127_3742522_11 TIGRFAM periplasmic serine protease, Do DeqQ family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 333.0
HFD3_k127_3742522_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 303.0
HFD3_k127_3742522_13 Polynucleotide adenylyltransferase K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000007332 258.0
HFD3_k127_3742522_14 peptidase K01415,K07386 - 3.4.24.71 0.000000000000000000000000000000000000000000000000000000000000000000007939 235.0
HFD3_k127_3742522_15 ABC transporter K02003,K05685 - - 0.00000000000000000000000000000000000000000000000000000000000000002229 231.0
HFD3_k127_3742522_16 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000002938 226.0
HFD3_k127_3742522_17 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.00000000000000000000000000000000000000000000000001323 184.0
HFD3_k127_3742522_18 BON domain - - - 0.00000000000000000000000000000000000000000000002967 177.0
HFD3_k127_3742522_19 NUDIX domain K03574 - 3.6.1.55 0.000000000000000000000000000000000000000001591 161.0
HFD3_k127_3742522_2 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 602.0
HFD3_k127_3742522_20 Appr-1'-p processing enzyme - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000001224 153.0
HFD3_k127_3742522_21 Belongs to the ompA family - - - 0.0000000000000000000000000000003519 132.0
HFD3_k127_3742522_22 - - - - 0.000000004095 65.0
HFD3_k127_3742522_23 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000008558 64.0
HFD3_k127_3742522_24 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000002624 57.0
HFD3_k127_3742522_3 glutamate decarboxylase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007532 596.0
HFD3_k127_3742522_4 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007195 547.0
HFD3_k127_3742522_5 lipoprotein localization to outer membrane K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 497.0
HFD3_k127_3742522_6 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 414.0
HFD3_k127_3742522_7 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 407.0
HFD3_k127_3742522_8 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006378 373.0
HFD3_k127_3742522_9 creatininase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007625 364.0
HFD3_k127_3753022_0 PFAM Protein kinase domain K12132 - 2.7.11.1 0.0 1147.0
HFD3_k127_3753022_1 Amidohydrolase family K06015 - 3.5.1.81 4.147e-218 691.0
HFD3_k127_3753022_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006608 280.0
HFD3_k127_3753022_11 SelR domain K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000005597 229.0
HFD3_k127_3753022_12 TIGRFAM N-terminal double-transmembrane domain - - - 0.00000000000000000000000000000000001881 155.0
HFD3_k127_3753022_2 SMART Elongator protein 3 MiaB NifB - - - 5.54e-214 678.0
HFD3_k127_3753022_3 MacB-like periplasmic core domain - - - 5.354e-201 653.0
HFD3_k127_3753022_4 efflux transmembrane transporter activity K02004 - - 9.261e-199 646.0
HFD3_k127_3753022_5 nuclear chromosome segregation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 581.0
HFD3_k127_3753022_6 Luciferase-like monooxygenase K17228 - 1.14.14.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 446.0
HFD3_k127_3753022_7 metallopeptidase activity K06212,K06402 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031224,GO:0031226,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008183 405.0
HFD3_k127_3753022_8 ATP-grasp - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 402.0
HFD3_k127_3753022_9 FRG - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 346.0
HFD3_k127_3773954_0 Putative glucoamylase K13688 - - 0.0 2734.0
HFD3_k127_3773954_1 Carboxyl transferase domain - - - 6.39e-207 655.0
HFD3_k127_3773954_10 Carboxypeptidase regulatory-like domain K18235 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004079 286.0
HFD3_k127_3773954_11 palmitoyl-(protein) hydrolase activity K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000002777 245.0
HFD3_k127_3773954_12 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000000005394 206.0
HFD3_k127_3773954_13 phosphotransferase related to Ser Thr protein kinases K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000007457 188.0
HFD3_k127_3773954_14 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00966,K16881 GO:0000166,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0003983,GO:0005488,GO:0006011,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009225,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0051748,GO:0055086,GO:0070569,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363 2.7.7.13,5.4.2.8 0.000000000000000000000000000000000000000000000713 178.0
HFD3_k127_3773954_15 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000009806 156.0
HFD3_k127_3773954_16 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000000000000000000000000000822 152.0
HFD3_k127_3773954_17 - - - - 0.00000000000000000000000000000000000145 153.0
HFD3_k127_3773954_18 PFAM von Willebrand factor type A - - - 0.00000000000000000000000000000000000746 149.0
HFD3_k127_3773954_19 TIGRFAM VWFA-related Acidobacterial domain - - - 0.000000000000000000000000000000002509 142.0
HFD3_k127_3773954_2 Protein of unknown function (DUF3500) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 575.0
HFD3_k127_3773954_20 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000009757 121.0
HFD3_k127_3773954_21 CYTH K05873 - 4.6.1.1 0.00000000000000000000000004498 115.0
HFD3_k127_3773954_22 Belongs to the ompA family - - - 0.00000000000000000000007726 110.0
HFD3_k127_3773954_23 Fatty acid desaturase - - - 0.000000000000000000007215 105.0
HFD3_k127_3773954_24 alkyl hydroperoxide reductase - - - 0.00000000000001773 77.0
HFD3_k127_3773954_26 Redoxin K03564 - 1.11.1.15 0.0000002518 54.0
HFD3_k127_3773954_3 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 562.0
HFD3_k127_3773954_4 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 487.0
HFD3_k127_3773954_5 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007507 477.0
HFD3_k127_3773954_6 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 480.0
HFD3_k127_3773954_7 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 469.0
HFD3_k127_3773954_8 Aldolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 364.0
HFD3_k127_3773954_9 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 319.0
HFD3_k127_3797103_0 TIGRFAM rhamnulose-1-phosphate aldolase alcohol dehydrogenase - - - 2.546e-319 994.0
HFD3_k127_3797103_1 isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 601.0
HFD3_k127_3797103_2 Alpha-L-rhamnosidase N-terminal domain K05989 - 3.2.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 577.0
HFD3_k127_3797103_3 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 359.0
HFD3_k127_3797103_4 D-galactarate dehydratase / Altronate hydrolase, C terminus K01685,K01708 - 4.2.1.42,4.2.1.7 0.000001312 55.0
HFD3_k127_3918570_0 Amino acid permease - - - 1.282e-250 794.0
HFD3_k127_3918570_1 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 2.604e-227 717.0
HFD3_k127_3918570_10 Sir2 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 323.0
HFD3_k127_3918570_11 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005454 308.0
HFD3_k127_3918570_12 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004799 286.0
HFD3_k127_3918570_13 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000002407 255.0
HFD3_k127_3918570_14 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000351 237.0
HFD3_k127_3918570_15 - - - - 0.00000000000000000000000000000000000000000000000000000002597 208.0
HFD3_k127_3918570_16 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000000000000001182 203.0
HFD3_k127_3918570_17 Domain of unknown function (DUF374) K09778 - - 0.00000000000000000000000000000000000000000000001733 181.0
HFD3_k127_3918570_18 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000000000000000000000000000000000001995 175.0
HFD3_k127_3918570_19 alpha beta - - - 0.00000000000000006898 97.0
HFD3_k127_3918570_2 FAD binding domain K07077 - - 2.579e-205 651.0
HFD3_k127_3918570_20 Cytochrome c554 and c-prime K03620 - - 0.00000000000002954 82.0
HFD3_k127_3918570_21 amine dehydrogenase activity - - - 0.000000000085 77.0
HFD3_k127_3918570_22 efflux transmembrane transporter activity - - - 0.000001225 51.0
HFD3_k127_3918570_23 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00006358 54.0
HFD3_k127_3918570_3 Dehydrogenase K02030,K17760,K19713 - 1.1.9.1,1.8.2.2 5.588e-197 638.0
HFD3_k127_3918570_4 COG0208 Ribonucleotide reductase, beta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 490.0
HFD3_k127_3918570_5 PKD domain containing protein K01337,K20276,K21449 - 3.4.21.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 527.0
HFD3_k127_3918570_6 glucose sorbosone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 434.0
HFD3_k127_3918570_7 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 430.0
HFD3_k127_3918570_8 D-alanyl-d-alanine carboxypeptidase K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007753 389.0
HFD3_k127_3918570_9 YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 373.0
HFD3_k127_3919431_0 Insulinase (Peptidase family M16) K07263 - - 1.564e-253 814.0
HFD3_k127_3919431_1 Prokaryotic cytochrome b561 - - - 2.005e-232 737.0
HFD3_k127_3919431_10 oxidoreductase activity K00274 - 1.4.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000101 299.0
HFD3_k127_3919431_11 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005735 282.0
HFD3_k127_3919431_12 dehydrogenases and related proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003112 255.0
HFD3_k127_3919431_13 Belongs to the glycosyltransferase 26 family K05946 - 2.4.1.187 0.000000000000000000000000000000000000000000000000000000000000001706 227.0
HFD3_k127_3919431_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000001876 243.0
HFD3_k127_3919431_15 Cytochrome c554 and c-prime K03620 - - 0.00000000000000000000000000000000000000000000000000000000000002384 232.0
HFD3_k127_3919431_16 Cytochrome b(N-terminal)/b6/petB K00412,K02635,K02637,K03887,K03891,K15879 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009512,GO:0009579,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044436,GO:0044459,GO:0044464,GO:0070069,GO:0071944 - 0.0000000000000000000000000000000000000000000000000002117 199.0
HFD3_k127_3919431_17 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.0000000000000000000000000000000000000000000000003762 180.0
HFD3_k127_3919431_18 hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000001987 135.0
HFD3_k127_3919431_19 PFAM Rieske 2Fe-2S K02636 - 1.10.9.1 0.0000000000000000000005592 101.0
HFD3_k127_3919431_2 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 480.0
HFD3_k127_3919431_20 Domain of unknown function (DU1801) - - - 0.000000000000000001176 92.0
HFD3_k127_3919431_21 YwiC-like protein - - - 0.000000000000000003903 94.0
HFD3_k127_3919431_22 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000003914 83.0
HFD3_k127_3919431_23 Universal stress protein - - - 0.000000000000001565 82.0
HFD3_k127_3919431_24 heat shock protein binding - - - 0.00009168 54.0
HFD3_k127_3919431_25 Cytochrome c553 K08738 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0001007 50.0
HFD3_k127_3919431_27 Belongs to the GSP D family - - - 0.0006581 50.0
HFD3_k127_3919431_3 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 479.0
HFD3_k127_3919431_4 Cytochrome c554 and c-prime K03620 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004122 404.0
HFD3_k127_3919431_5 phosphoesterase RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009271 403.0
HFD3_k127_3919431_6 Phosphoenolpyruvate phosphomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 382.0
HFD3_k127_3919431_7 denitrification pathway K02569,K15876 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005698 398.0
HFD3_k127_3919431_8 Glycosyltransferase like family 2 K10012 - 2.4.2.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 376.0
HFD3_k127_3919431_9 calcium, potassium:sodium antiporter activity K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 346.0
HFD3_k127_3943720_0 serine threonine protein kinase K12132 - 2.7.11.1 6.638e-230 745.0
HFD3_k127_3943720_1 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 584.0
HFD3_k127_3943720_10 FMN biosynthetic process K01091,K07732 - 2.7.1.161,3.1.3.18 0.0007563 44.0
HFD3_k127_3943720_2 Isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008113 356.0
HFD3_k127_3943720_3 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007016 351.0
HFD3_k127_3943720_4 - - - - 0.000000000000000000000000000000000000000000000005727 186.0
HFD3_k127_3943720_5 nuclease - - - 0.0000000000000000000000000000001413 125.0
HFD3_k127_3943720_6 chaperone-mediated protein folding - - - 0.0000000000000000000000000697 123.0
HFD3_k127_3943720_7 Belongs to the 'phage' integrase family - - - 0.000000000000004507 82.0
HFD3_k127_3943720_8 Subtilase family - - - 0.0000000000007076 78.0
HFD3_k127_3954044_0 ASPIC and UnbV - - - 6.902e-246 773.0
HFD3_k127_3954044_1 Belongs to the glycosyl hydrolase 31 family K01811 - 3.2.1.177 5.125e-205 650.0
HFD3_k127_3954044_2 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000005323 216.0
HFD3_k127_3954048_0 DinB family - - - 0.00000000000000000000000000000000000000000000000000000000000331 212.0
HFD3_k127_3954048_1 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.00000000000000000000000000000000000000000009234 163.0
HFD3_k127_3954048_2 - - - - 0.0000000000000000000000000000000000008191 151.0
HFD3_k127_3954048_3 Rubrerythrin - - - 0.0000000000001122 73.0
HFD3_k127_3956912_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008955 487.0
HFD3_k127_3956912_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 311.0
HFD3_k127_3956912_2 Protein of unknown function (DUF3616) - - - 0.0000000000004697 80.0
HFD3_k127_3970865_0 Polysaccharide biosynthesis protein K02851 - 2.7.8.33,2.7.8.35 3.703e-200 639.0
HFD3_k127_3970865_1 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 562.0
HFD3_k127_3970865_10 domain protein K14194 - - 0.0000000000000000002846 102.0
HFD3_k127_3970865_11 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000000007464 88.0
HFD3_k127_3970865_12 Carboxypeptidase regulatory-like domain - - - 0.000000000000001484 91.0
HFD3_k127_3970865_13 - - - - 0.000000000008705 73.0
HFD3_k127_3970865_14 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000002724 65.0
HFD3_k127_3970865_15 - - - - 0.000255 47.0
HFD3_k127_3970865_2 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 493.0
HFD3_k127_3970865_3 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 466.0
HFD3_k127_3970865_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 392.0
HFD3_k127_3970865_5 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000001862 218.0
HFD3_k127_3970865_6 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000003874 199.0
HFD3_k127_3970865_7 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000002258 149.0
HFD3_k127_3970865_8 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000007321 145.0
HFD3_k127_3970865_9 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - - 0.0000000000000000000000000000000000004288 149.0
HFD3_k127_3975034_0 Transcriptional regulator K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001142 259.0
HFD3_k127_3975034_1 Thioesterase superfamily K07107 - - 0.00000000000000000000816 97.0
HFD3_k127_3975034_2 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0022607,GO:0030288,GO:0030313,GO:0031647,GO:0031975,GO:0033218,GO:0036211,GO:0042277,GO:0042597,GO:0043163,GO:0043165,GO:0043170,GO:0043412,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0044764,GO:0045229,GO:0050821,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0060274,GO:0061024,GO:0061077,GO:0065007,GO:0065008,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564 5.2.1.8 0.0000000000000002438 91.0
HFD3_k127_3975034_3 PPIC-type PPIASE domain K03769,K03770,K03771,K07533 - 5.2.1.8 0.0000000000003878 79.0
HFD3_k127_3975034_4 Ribosome-associated heat shock protein implicated in recycling of 50S subunit - - - 0.0000000000007804 73.0
HFD3_k127_3977176_0 Sortilin, neurotensin receptor 3, - - - 0.0 1420.0
HFD3_k127_3977176_1 GMC oxidoreductase - - - 1.05e-301 964.0
HFD3_k127_3977176_10 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 494.0
HFD3_k127_3977176_11 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 485.0
HFD3_k127_3977176_12 His Kinase A (phosphoacceptor) domain K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 503.0
HFD3_k127_3977176_13 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 460.0
HFD3_k127_3977176_14 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 478.0
HFD3_k127_3977176_15 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005509 461.0
HFD3_k127_3977176_16 Peptidase M56 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 456.0
HFD3_k127_3977176_17 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 451.0
HFD3_k127_3977176_18 agmatine deiminase activity K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 430.0
HFD3_k127_3977176_19 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 383.0
HFD3_k127_3977176_2 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 1.383e-277 876.0
HFD3_k127_3977176_20 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 371.0
HFD3_k127_3977176_21 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 360.0
HFD3_k127_3977176_22 glucose sorbosone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004116 356.0
HFD3_k127_3977176_23 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006224 325.0
HFD3_k127_3977176_24 Acts as a magnesium transporter K03281,K04767,K06213,K15986 GO:0000287,GO:0003674,GO:0005488,GO:0005515,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015693,GO:0030001,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0051179,GO:0051234,GO:0070838,GO:0072511 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 325.0
HFD3_k127_3977176_25 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 314.0
HFD3_k127_3977176_26 PFAM Branched-chain amino acid transport system permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 305.0
HFD3_k127_3977176_27 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 312.0
HFD3_k127_3977176_28 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006975 289.0
HFD3_k127_3977176_29 Cell shape determining protein MreB Mrl K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001936 291.0
HFD3_k127_3977176_3 peptidase S9A, prolyl oligopeptidase domain protein beta-propeller K01354 - 3.4.21.83 1.787e-268 843.0
HFD3_k127_3977176_30 Belongs to the GPAT DAPAT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005573 287.0
HFD3_k127_3977176_31 Phosphoribulokinase / Uridine kinase family K00855,K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.19,2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000007161 258.0
HFD3_k127_3977176_32 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000009791 241.0
HFD3_k127_3977176_33 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000001269 217.0
HFD3_k127_3977176_34 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000008359 196.0
HFD3_k127_3977176_35 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000000000000000009299 171.0
HFD3_k127_3977176_36 Putative heavy-metal-binding - - - 0.00000000000000000000000000000000000000004393 157.0
HFD3_k127_3977176_37 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.0000000000000000000000000000000000000004674 152.0
HFD3_k127_3977176_38 alkylbase DNA N-glycosylase activity K03652 - 3.2.2.21 0.000000000000000000000000000000000002221 146.0
HFD3_k127_3977176_39 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K01259 - 3.4.11.5 0.0000000000000000000000000000001012 138.0
HFD3_k127_3977176_4 PFAM TonB-dependent Receptor K16090 - - 1.108e-222 715.0
HFD3_k127_3977176_40 Haem-binding domain - - - 0.0000000000000000000000000000005156 129.0
HFD3_k127_3977176_41 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000001743 133.0
HFD3_k127_3977176_42 CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000000202 119.0
HFD3_k127_3977176_43 - - - - 0.000000000000000000000001148 108.0
HFD3_k127_3977176_44 Domain of unknown function (DUF4870) - - - 0.00000000000005207 78.0
HFD3_k127_3977176_45 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000005734 71.0
HFD3_k127_3977176_46 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000006326 69.0
HFD3_k127_3977176_47 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000008954 75.0
HFD3_k127_3977176_48 Tetratricopeptide repeats - - - 0.00000003939 65.0
HFD3_k127_3977176_5 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 2.202e-212 664.0
HFD3_k127_3977176_50 SnoaL-like polyketide cyclase - - - 0.0000004295 61.0
HFD3_k127_3977176_51 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000003174 60.0
HFD3_k127_3977176_52 S-layer homology domain - - - 0.00007279 50.0
HFD3_k127_3977176_53 SnoaL-like domain - - - 0.0009063 51.0
HFD3_k127_3977176_6 Belongs to the UbiD family K03182 - 4.1.1.98 6.044e-208 661.0
HFD3_k127_3977176_7 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009172 591.0
HFD3_k127_3977176_8 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 610.0
HFD3_k127_3977176_9 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 587.0
HFD3_k127_4000861_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 7.464e-305 947.0
HFD3_k127_4000861_1 FeS assembly protein SufB K07033,K09014 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - 5.284e-276 854.0
HFD3_k127_4000861_10 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006979 565.0
HFD3_k127_4000861_100 PFAM ThiJ PfpI - - - 0.0002033 46.0
HFD3_k127_4000861_101 Cell division protein FtsQ K03589 - - 0.0005669 51.0
HFD3_k127_4000861_102 - - - - 0.0007529 49.0
HFD3_k127_4000861_103 alpha-galactosidase K01179,K01183 - 3.2.1.14,3.2.1.4 0.0009088 51.0
HFD3_k127_4000861_11 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 548.0
HFD3_k127_4000861_12 Organic Anion Transporter Polypeptide (OATP) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 518.0
HFD3_k127_4000861_13 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 518.0
HFD3_k127_4000861_14 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 502.0
HFD3_k127_4000861_15 BNR repeat-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 460.0
HFD3_k127_4000861_16 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004353 467.0
HFD3_k127_4000861_17 DNA polymerase K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 457.0
HFD3_k127_4000861_18 FeS assembly protein SufD K07033,K09015 GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0050896,GO:0051186,GO:0071840 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 448.0
HFD3_k127_4000861_19 ATPase activity K02045 - 3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 455.0
HFD3_k127_4000861_2 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 6.481e-247 771.0
HFD3_k127_4000861_20 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 440.0
HFD3_k127_4000861_21 7TM-HD extracellular K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 458.0
HFD3_k127_4000861_22 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 436.0
HFD3_k127_4000861_23 proteins of the AP superfamily K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 437.0
HFD3_k127_4000861_24 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000069 428.0
HFD3_k127_4000861_25 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007351 443.0
HFD3_k127_4000861_26 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009086 424.0
HFD3_k127_4000861_27 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 416.0
HFD3_k127_4000861_28 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 415.0
HFD3_k127_4000861_29 Sulfate ABC transporter periplasmic sulfate-binding protein K02048 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 408.0
HFD3_k127_4000861_3 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 3.678e-246 770.0
HFD3_k127_4000861_30 TIGRFAM FeS assembly ATPase SufC K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 393.0
HFD3_k127_4000861_31 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005614 400.0
HFD3_k127_4000861_32 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006182 395.0
HFD3_k127_4000861_33 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004431 402.0
HFD3_k127_4000861_34 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 375.0
HFD3_k127_4000861_35 SPFH domain-Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 363.0
HFD3_k127_4000861_36 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 361.0
HFD3_k127_4000861_37 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 350.0
HFD3_k127_4000861_38 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004951 353.0
HFD3_k127_4000861_39 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 334.0
HFD3_k127_4000861_4 heat shock protein 70 K04043,K04044 - - 3.821e-218 693.0
HFD3_k127_4000861_40 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 325.0
HFD3_k127_4000861_41 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 314.0
HFD3_k127_4000861_42 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 301.0
HFD3_k127_4000861_43 PFAM response regulator receiver K07665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 288.0
HFD3_k127_4000861_44 cytokinin biosynthetic process K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008918 287.0
HFD3_k127_4000861_45 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002006 283.0
HFD3_k127_4000861_46 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002196 286.0
HFD3_k127_4000861_47 TIGRFAM sulfate ABC transporter K02046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004043 279.0
HFD3_k127_4000861_48 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000146 280.0
HFD3_k127_4000861_49 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001642 271.0
HFD3_k127_4000861_5 Aldehyde dehydrogenase family K00128,K00130 - 1.2.1.3,1.2.1.8 4.118e-214 674.0
HFD3_k127_4000861_50 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006033 274.0
HFD3_k127_4000861_51 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009974 273.0
HFD3_k127_4000861_52 PFAM phospholipase Carboxylesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005293 268.0
HFD3_k127_4000861_53 sulfate ABC transporter K02047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003035 269.0
HFD3_k127_4000861_54 PFAM aminotransferase class I and II K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003521 247.0
HFD3_k127_4000861_55 PFAM Rhomboid family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000893 250.0
HFD3_k127_4000861_56 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000003168 239.0
HFD3_k127_4000861_57 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946,K07123 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000345 243.0
HFD3_k127_4000861_58 Transporter associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000005436 241.0
HFD3_k127_4000861_59 ZIP Zinc transporter K07238,K11021,K16267 - - 0.00000000000000000000000000000000000000000000000000000000000000005216 231.0
HFD3_k127_4000861_6 PLD-like domain K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006198 611.0
HFD3_k127_4000861_60 lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000006124 235.0
HFD3_k127_4000861_61 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.00000000000000000000000000000000000000000000000000000000000000009381 224.0
HFD3_k127_4000861_62 Belongs to the UPF0502 family K09915 - - 0.000000000000000000000000000000000000000000000000000000000000009628 222.0
HFD3_k127_4000861_63 PFAM YdjC family protein - - - 0.000000000000000000000000000000000000000000000000000000001017 211.0
HFD3_k127_4000861_64 TIGRFAM SUF system FeS K04488 - - 0.00000000000000000000000000000000000000000000000000000003926 201.0
HFD3_k127_4000861_65 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000006358 189.0
HFD3_k127_4000861_66 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000006436 192.0
HFD3_k127_4000861_67 phosphate-selective porin O and P K07221 - - 0.000000000000000000000000000000000000000000000000001045 203.0
HFD3_k127_4000861_68 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000001913 187.0
HFD3_k127_4000861_69 Methylates ribosomal protein L11 K02687 - - 0.000000000000000000000000000000000000000000000000006955 192.0
HFD3_k127_4000861_7 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 593.0
HFD3_k127_4000861_70 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000009731 187.0
HFD3_k127_4000861_71 PFAM Nickel cobalt transporter, high-affinity - - - 0.00000000000000000000000000000000000000000000001586 179.0
HFD3_k127_4000861_72 PFAM heat shock protein DnaJ K04082 - - 0.00000000000000000000000000000000000000000000003412 179.0
HFD3_k127_4000861_73 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000001015 173.0
HFD3_k127_4000861_74 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000000000000216 166.0
HFD3_k127_4000861_75 metal-sulfur cluster biosynthetic enzyme K02612 - - 0.00000000000000000000000000000000000000009551 154.0
HFD3_k127_4000861_76 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.00000000000000000000000000000000000002546 149.0
HFD3_k127_4000861_77 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000006379 139.0
HFD3_k127_4000861_78 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.00000000000000000000000000000000006518 139.0
HFD3_k127_4000861_79 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000000000000001313 136.0
HFD3_k127_4000861_8 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 591.0
HFD3_k127_4000861_80 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000006199 135.0
HFD3_k127_4000861_81 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000001907 130.0
HFD3_k127_4000861_82 nucleotidyltransferase activity - - - 0.0000000000000000000000000000003885 131.0
HFD3_k127_4000861_83 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000002931 117.0
HFD3_k127_4000861_84 Methanol dehydrogenase K06872 - - 0.0000000000000000000000000003094 125.0
HFD3_k127_4000861_85 - - - - 0.000000000000000000000001085 113.0
HFD3_k127_4000861_86 Thioredoxin-like - - - 0.00000000000000000000001654 109.0
HFD3_k127_4000861_87 Fe-S assembly protein IscX - GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772 - 0.0000000000000000000003519 97.0
HFD3_k127_4000861_88 C4-type zinc ribbon domain K07164 - - 0.000000000000000000001404 104.0
HFD3_k127_4000861_89 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000002862 97.0
HFD3_k127_4000861_9 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 579.0
HFD3_k127_4000861_90 - - - - 0.00000000000000000004362 93.0
HFD3_k127_4000861_91 - - - - 0.00000000000005884 83.0
HFD3_k127_4000861_92 AraC-like ligand binding domain - - - 0.0000000000001341 75.0
HFD3_k127_4000861_93 Bacterial regulatory protein, Fis family - - - 0.0000000004722 64.0
HFD3_k127_4000861_94 - - - - 0.0000000145 61.0
HFD3_k127_4000861_95 PFAM Tetratricopeptide - - - 0.0000001774 62.0
HFD3_k127_4000861_97 colicin V production K03558 - - 0.000004765 56.0
HFD3_k127_4000861_98 - K06950 - - 0.00001962 50.0
HFD3_k127_4000861_99 PFAM sigma-70 region 2 domain protein K03088 - - 0.00007794 54.0
HFD3_k127_400358_0 alpha-L-arabinofuranosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006008 545.0
HFD3_k127_400358_1 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.000000000000000000000000000000000000000000000000000000000000000000008831 248.0
HFD3_k127_400358_2 methyltransferase - - - 0.000000000000000000000000000000000000000000000005932 176.0
HFD3_k127_4011922_0 Tricorn protease homolog - - - 0.0 1402.0
HFD3_k127_4011922_1 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000001489 173.0
HFD3_k127_4011922_2 membrane protein (DUF2127) - - - 0.000000000000000000000000000000000000000003847 160.0
HFD3_k127_4011922_3 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000001315 132.0
HFD3_k127_4045206_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 6.54e-266 842.0
HFD3_k127_4045206_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.798e-218 683.0
HFD3_k127_4045206_10 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009733 426.0
HFD3_k127_4045206_11 Alanine-glyoxylate amino-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 391.0
HFD3_k127_4045206_12 nuclease activity - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 377.0
HFD3_k127_4045206_13 Asparaginase K01444 - 3.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 346.0
HFD3_k127_4045206_14 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 371.0
HFD3_k127_4045206_15 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 310.0
HFD3_k127_4045206_16 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005653 304.0
HFD3_k127_4045206_17 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007472 293.0
HFD3_k127_4045206_18 hydrolase activity, hydrolyzing O-glycosyl compounds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002816 289.0
HFD3_k127_4045206_19 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000214 248.0
HFD3_k127_4045206_2 PFAM AMP-dependent synthetase and ligase K00666 - - 1.791e-214 679.0
HFD3_k127_4045206_20 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000002776 260.0
HFD3_k127_4045206_21 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000007222 247.0
HFD3_k127_4045206_22 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000007047 249.0
HFD3_k127_4045206_23 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000009689 233.0
HFD3_k127_4045206_24 abc transporter, permease K02018 - - 0.000000000000000000000000000000000000000000000000000000000000000004374 233.0
HFD3_k127_4045206_25 ABC-type molybdate transport system, ATPase component K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000007344 240.0
HFD3_k127_4045206_26 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000002152 224.0
HFD3_k127_4045206_27 - - - - 0.000000000000000000000000000000000000000000000000000000001336 215.0
HFD3_k127_4045206_28 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.00000000000000000000000000000000000000000000000000000001674 205.0
HFD3_k127_4045206_29 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000008775 196.0
HFD3_k127_4045206_3 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 2.1e-204 644.0
HFD3_k127_4045206_30 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000002185 197.0
HFD3_k127_4045206_31 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000005373 193.0
HFD3_k127_4045206_32 Phosphodiester glycosidase - - - 0.00000000000000000000000000000000000000000000000001896 195.0
HFD3_k127_4045206_33 - K07018 - - 0.0000000000000000000000000000000000000000000000002169 185.0
HFD3_k127_4045206_34 DinB superfamily - - - 0.000000000000000000000000000000000000000000004871 168.0
HFD3_k127_4045206_35 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000004015 144.0
HFD3_k127_4045206_36 phosphohistidine phosphatase K08296 - - 0.000000000000000000000000000000000001658 143.0
HFD3_k127_4045206_37 Cytidylate kinase-like family - - - 0.000000000000000000000000000000000018 143.0
HFD3_k127_4045206_38 Probable zinc-ribbon domain - - - 0.00000000000000000000000000000001423 131.0
HFD3_k127_4045206_39 von Willebrand factor, type A - - - 0.0000000000000000000000000005491 130.0
HFD3_k127_4045206_4 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 547.0
HFD3_k127_4045206_40 5'-nucleotidase - - - 0.000000000000000000000008507 115.0
HFD3_k127_4045206_41 Tyrosine phosphatase family - - - 0.000000000000000000004126 101.0
HFD3_k127_4045206_42 LysM domain K01185,K02030,K04043 - 3.2.1.17 0.000000000000000001226 97.0
HFD3_k127_4045206_43 oxidoreductase activity K12511 - - 0.000000000000000003729 96.0
HFD3_k127_4045206_44 sequence-specific DNA binding K03719 - - 0.00000000000000009077 83.0
HFD3_k127_4045206_45 iron ion homeostasis - - - 0.0000000000000003135 91.0
HFD3_k127_4045206_46 YacP-like NYN domain - - - 0.00000000000009228 78.0
HFD3_k127_4045206_47 Endonuclease I - - - 0.000000006296 68.0
HFD3_k127_4045206_5 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 534.0
HFD3_k127_4045206_6 transposase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 482.0
HFD3_k127_4045206_7 Pyrimidine nucleoside phosphorylase C-terminal domain K00756,K00758 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2,2.4.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 468.0
HFD3_k127_4045206_8 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00263 - 1.4.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 464.0
HFD3_k127_4045206_9 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004298 460.0
HFD3_k127_4089605_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388,K12527 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,1.97.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 598.0
HFD3_k127_4089605_1 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006014 386.0
HFD3_k127_4089605_10 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000001388 87.0
HFD3_k127_4089605_12 protein secretion K03116 - - 0.0000000001276 64.0
HFD3_k127_4089605_13 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000009166 57.0
HFD3_k127_4089605_14 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00002336 54.0
HFD3_k127_4089605_2 Cytochrome b(N-terminal)/b6/petB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001484 281.0
HFD3_k127_4089605_3 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001754 288.0
HFD3_k127_4089605_4 Polysaccharide lyase family 4, domain II - - - 0.00000000000000000000000000000000000000002089 160.0
HFD3_k127_4089605_5 C-terminal domain of CHU protein family - - - 0.0000000000000000000000000000000000000002345 172.0
HFD3_k127_4089605_6 ABC transporter transmembrane region K11085 - - 0.0000000000000000000000000000000003143 133.0
HFD3_k127_4089605_7 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.00000000000000000000000000000004752 130.0
HFD3_k127_4089605_8 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000003214 130.0
HFD3_k127_4089605_9 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.00000000000000000000000001505 118.0
HFD3_k127_4100275_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1024.0
HFD3_k127_4100275_1 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 502.0
HFD3_k127_4100275_2 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 418.0
HFD3_k127_4100275_3 PFAM Methyltransferase type 12 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001057 262.0
HFD3_k127_4100275_4 Rhodanese-like domain - - - 0.00000000000000000000000000000000000004003 151.0
HFD3_k127_4100275_5 F420H(2)-dependent quinone reductase - - - 0.0000000000000000000000000000172 120.0
HFD3_k127_4100275_6 lysyltransferase activity K07027 - - 0.000000000000003196 89.0
HFD3_k127_4100275_7 Putative peptidoglycan binding domain - - - 0.000000000002306 80.0
HFD3_k127_4100275_8 Autotransporter beta-domain - - - 0.000009473 59.0
HFD3_k127_4118193_0 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 382.0
HFD3_k127_4118193_1 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000008172 209.0
HFD3_k127_4118193_2 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000005479 205.0
HFD3_k127_4118193_3 D,D-heptose 1,7-bisphosphate phosphatase K02841,K02843,K02849,K03271,K03272,K03273 - 2.7.1.167,2.7.7.70,3.1.3.82,3.1.3.83,5.3.1.28 0.00000000000000000000000000000000000003922 158.0
HFD3_k127_4118193_4 Bacterial membrane protein YfhO - - - 0.000000000000000000000001055 116.0
HFD3_k127_4118193_5 polysaccharide deacetylase - - - 0.0000000000000000000003771 108.0
HFD3_k127_4118193_6 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000003856 99.0
HFD3_k127_4122652_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007282 629.0
HFD3_k127_4122652_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 512.0
HFD3_k127_4122652_10 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000001201 182.0
HFD3_k127_4122652_11 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000005416 178.0
HFD3_k127_4122652_12 Sulfatase-modifying factor enzyme 1 K20333 - - 0.00000000000000000000000000000000000000003031 175.0
HFD3_k127_4122652_13 Peptidase family M50 K06402 - - 0.00000000000000000000000000000000000000006287 160.0
HFD3_k127_4122652_14 PspA/IM30 family K03969 - - 0.0000000000000000000000000000000001236 143.0
HFD3_k127_4122652_15 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000001411 131.0
HFD3_k127_4122652_16 protein adenylyltransferase activity - GO:0000166,GO:0003008,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005783,GO:0005789,GO:0005886,GO:0006464,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006836,GO:0006950,GO:0006952,GO:0007600,GO:0007601,GO:0007610,GO:0007632,GO:0008081,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009416,GO:0009581,GO:0009582,GO:0009583,GO:0009584,GO:0009605,GO:0009607,GO:0009617,GO:0009628,GO:0009966,GO:0009987,GO:0010646,GO:0012505,GO:0015696,GO:0016020,GO:0016021,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0017076,GO:0018117,GO:0018175,GO:0019538,GO:0023051,GO:0030176,GO:0030544,GO:0030554,GO:0031072,GO:0031224,GO:0031227,GO:0031967,GO:0031975,GO:0031984,GO:0032501,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034260,GO:0034976,GO:0035639,GO:0036094,GO:0036211,GO:0042175,GO:0042578,GO:0042742,GO:0042802,GO:0042803,GO:0043086,GO:0043087,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044092,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0044601,GO:0044602,GO:0044603,GO:0045117,GO:0046983,GO:0048519,GO:0048583,GO:0050789,GO:0050790,GO:0050794,GO:0050829,GO:0050877,GO:0050896,GO:0050906,GO:0050908,GO:0050953,GO:0050962,GO:0051087,GO:0051179,GO:0051234,GO:0051336,GO:0051346,GO:0051606,GO:0051608,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0065009,GO:0070566,GO:0070733,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0080134,GO:0080135,GO:0097159,GO:0097367,GO:0098542,GO:0098827,GO:0140096,GO:1900101,GO:1901265,GO:1901363,GO:1901564,GO:1903894,GO:1905897 - 0.0000000000002668 79.0
HFD3_k127_4122652_17 - - - - 0.000000001371 68.0
HFD3_k127_4122652_18 EF-hand domain pair - - - 0.000000005429 66.0
HFD3_k127_4122652_19 Sh3 type 3 domain protein - - - 0.000001056 61.0
HFD3_k127_4122652_2 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007013 457.0
HFD3_k127_4122652_20 Methyltransferase domain - - - 0.0006682 47.0
HFD3_k127_4122652_3 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 382.0
HFD3_k127_4122652_4 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 323.0
HFD3_k127_4122652_5 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 299.0
HFD3_k127_4122652_6 ArgK protein K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000575 271.0
HFD3_k127_4122652_7 Haemolysin-III related K11068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005082 270.0
HFD3_k127_4122652_8 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000216 227.0
HFD3_k127_4122652_9 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000001819 192.0
HFD3_k127_4128745_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003879 499.0
HFD3_k127_4128745_1 associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 370.0
HFD3_k127_4128745_2 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000001222 161.0
HFD3_k127_4154837_0 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007687 317.0
HFD3_k127_4154837_1 palmitoyl-(protein) hydrolase activity K06999 - - 0.000000000000000000000000000000000000000000000000000000000000008599 235.0
HFD3_k127_4154837_2 von Willebrand factor, type A K07114 - - 0.0000000000000000000003952 111.0
HFD3_k127_4154837_3 PFAM Uncharacterised BCR, COG1649 - - - 0.000000000000000000002039 112.0
HFD3_k127_4154837_4 Carboxypeptidase regulatory-like domain - - - 0.000000000000001286 81.0
HFD3_k127_4154837_5 amine dehydrogenase activity - - - 0.00000000005008 78.0
HFD3_k127_4218693_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004616 364.0
HFD3_k127_4218693_1 WD40 repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001439 273.0
HFD3_k127_4218693_2 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000004548 234.0
HFD3_k127_4218693_3 Domain of Unknown function (DUF542) K07322 - - 0.00000000000000000000000000000000000000000000000000646 185.0
HFD3_k127_4218693_4 cheY-homologous receiver domain - - - 0.00000000000000000000000000000002948 131.0
HFD3_k127_4294167_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006624 599.0
HFD3_k127_4294167_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 370.0
HFD3_k127_4294167_2 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000000000000002272 141.0
HFD3_k127_4294167_3 Belongs to the eIF-2B alpha beta delta subunits family K03680 - - 0.000000000000000000000000000002572 132.0
HFD3_k127_4294167_4 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000007269 115.0
HFD3_k127_4294167_5 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000001209 83.0
HFD3_k127_4294167_6 sodium proton antiporter K03316 - - 0.000000000006256 69.0
HFD3_k127_4309996_0 Uncharacterised protein family (UPF0182) K09118 - - 1.281e-219 715.0
HFD3_k127_4309996_1 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 397.0
HFD3_k127_4309996_10 Tetratricopeptide repeat - - - 0.00000000003636 76.0
HFD3_k127_4309996_11 Domain of unknown function (DUF4340) - - - 0.00001858 57.0
HFD3_k127_4309996_2 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 372.0
HFD3_k127_4309996_3 ABC-type uncharacterized transport system K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 373.0
HFD3_k127_4309996_4 PFAM type I phosphodiesterase nucleotide pyrophosphatase K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008008 293.0
HFD3_k127_4309996_5 ABC-type transport system involved in multi-copper enzyme maturation K01992 - - 0.0000000000000000000000000000000000000000000000000000000000002196 220.0
HFD3_k127_4309996_6 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000002883 194.0
HFD3_k127_4309996_7 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000005641 177.0
HFD3_k127_4309996_8 Predicted membrane protein (DUF2231) - - - 0.000000000000000000000000000000000000000003847 160.0
HFD3_k127_4309996_9 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000001075 124.0
HFD3_k127_4372338_0 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 389.0
HFD3_k127_4372338_1 Aminotransferase class-V K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008062 392.0
HFD3_k127_4372338_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 363.0
HFD3_k127_4372338_3 homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000002165 231.0
HFD3_k127_4391196_0 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004314 608.0
HFD3_k127_4391196_1 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005123 287.0
HFD3_k127_4391196_2 COG0840 Methyl-accepting chemotaxis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002421 278.0
HFD3_k127_4391196_3 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000006709 262.0
HFD3_k127_4391196_4 ECF sigma factor - - - 0.000000000000000000000000000000007193 133.0
HFD3_k127_4391196_5 GYD domain - - - 0.00000000000000000001469 96.0
HFD3_k127_4451899_0 Major Facilitator Superfamily - - - 2.661e-204 649.0
HFD3_k127_4451899_1 Ftsk_gamma K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005525 578.0
HFD3_k127_4451899_10 competence protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000004442 235.0
HFD3_k127_4451899_11 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000008839 233.0
HFD3_k127_4451899_12 glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000004548 234.0
HFD3_k127_4451899_13 Belongs to the peptidase M50B family - - - 0.00000000000000000000000000000000000000000000000000000001136 213.0
HFD3_k127_4451899_14 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000000000000000006459 198.0
HFD3_k127_4451899_15 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.0000000000000000000000000000000000000000000000000005422 188.0
HFD3_k127_4451899_16 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.00000000000000000000000000000000000000000000009769 173.0
HFD3_k127_4451899_17 Pfam Zn-finger in ubiquitin-hydrolases and other protein K03455 - - 0.00000000000000000000000000000000000000001032 154.0
HFD3_k127_4451899_18 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.0000000000000000000000000000000001935 142.0
HFD3_k127_4451899_19 Thioesterase-like superfamily - - - 0.00000000000000000000000000000001613 131.0
HFD3_k127_4451899_2 AMP-binding enzyme C-terminal domain K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007777 543.0
HFD3_k127_4451899_20 TIGRFAM phosphohistidine phosphatase SixA K08296 - - 0.00000000000000000000000003207 114.0
HFD3_k127_4451899_3 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046385,GO:0046483,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005053 442.0
HFD3_k127_4451899_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006359 412.0
HFD3_k127_4451899_5 Ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 414.0
HFD3_k127_4451899_6 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 407.0
HFD3_k127_4451899_7 Belongs to the Pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005686 362.0
HFD3_k127_4451899_8 NADPH:quinone reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 351.0
HFD3_k127_4451899_9 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000001051 287.0
HFD3_k127_4503208_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 5.14e-229 719.0
HFD3_k127_4503208_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 521.0
HFD3_k127_4503208_10 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000006677 70.0
HFD3_k127_4503208_11 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000009344 66.0
HFD3_k127_4503208_2 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 386.0
HFD3_k127_4503208_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 354.0
HFD3_k127_4503208_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000421 286.0
HFD3_k127_4503208_5 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008728 270.0
HFD3_k127_4503208_6 Cell cycle protein K05837 - - 0.000000000000000000000000000000004378 136.0
HFD3_k127_4503208_7 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000003435 109.0
HFD3_k127_4503208_8 VanZ like family - - - 0.00000000000000000046 93.0
HFD3_k127_4503208_9 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.000000000001518 72.0
HFD3_k127_4522951_0 Fibronectin type III-like domain K05349 - 3.2.1.21 0.0 1055.0
HFD3_k127_4522951_1 Belongs to the glycosyl hydrolase 67 family K01235 - 3.2.1.139 4.576e-285 895.0
HFD3_k127_4522951_10 ABC-type sugar transport system periplasmic component K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008498 393.0
HFD3_k127_4522951_11 carboxymethylenebutenolidase activity K01061,K07100 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 387.0
HFD3_k127_4522951_12 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008748 317.0
HFD3_k127_4522951_13 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009963 254.0
HFD3_k127_4522951_14 FCD K05799 - - 0.00000000000000000000000000000000000000000000000000000000000000000007803 240.0
HFD3_k127_4522951_15 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000001656 96.0
HFD3_k127_4522951_16 PFAM ROK family - - - 0.00000000000000003794 87.0
HFD3_k127_4522951_17 TIGRFAM galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.0000000000005972 70.0
HFD3_k127_4522951_2 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000703 581.0
HFD3_k127_4522951_3 Coagulation factor 5 8 type domain protein K01206 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 565.0
HFD3_k127_4522951_4 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 550.0
HFD3_k127_4522951_5 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004784 504.0
HFD3_k127_4522951_6 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000399 474.0
HFD3_k127_4522951_7 Glycosyl hydrolase family 10 K01181 - 3.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004325 495.0
HFD3_k127_4522951_8 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004192 420.0
HFD3_k127_4522951_9 inositol monophosphate 1-phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007983 414.0
HFD3_k127_4569086_0 Penicillin-binding Protein K05364 - - 0.0000000000000000000000000000000000000000000000000000009755 213.0
HFD3_k127_4569086_1 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000002979 173.0
HFD3_k127_4569086_2 Forkhead associated domain K03466 - - 0.000000003888 67.0
HFD3_k127_4569086_3 Belongs to the SEDS family K03588 GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136 - 0.00008429 54.0
HFD3_k127_4635674_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1315.0
HFD3_k127_4635674_1 valine-tRNA ligase activity K01873 GO:0000287,GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006417,GO:0006418,GO:0006438,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045903,GO:0046483,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0052689,GO:0060255,GO:0061475,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:2000112 6.1.1.9 1.059e-314 986.0
HFD3_k127_4635674_10 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002522 263.0
HFD3_k127_4635674_11 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000001805 234.0
HFD3_k127_4635674_12 TrkA-C domain K03499 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000002839 194.0
HFD3_k127_4635674_13 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.0000000000000000000000000000000000000000000001028 177.0
HFD3_k127_4635674_14 COG1905 NADH ubiquinone oxidoreductase 24 kD subunit K00334,K03943 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000001303 160.0
HFD3_k127_4635674_15 GGDEF domain - - - 0.000000000000000000000000000000000000000005146 167.0
HFD3_k127_4635674_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000003502 156.0
HFD3_k127_4635674_17 4Fe-4S dicluster domain K05524 - - 0.0000000000000000000000000000000000000006034 150.0
HFD3_k127_4635674_18 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000001759 164.0
HFD3_k127_4635674_19 cheY-homologous receiver domain - - - 0.000000000000000000000000000000009038 146.0
HFD3_k127_4635674_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 557.0
HFD3_k127_4635674_20 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000001123 108.0
HFD3_k127_4635674_21 response regulator, receiver - - - 0.00000000000000000000004649 103.0
HFD3_k127_4635674_22 Putative NAD(P)-binding K03499 - - 0.000000000000000000001353 108.0
HFD3_k127_4635674_23 - - - - 0.0000000000000009608 83.0
HFD3_k127_4635674_24 Fungalysin metallopeptidase (M36) - - - 0.0000000000000505 87.0
HFD3_k127_4635674_25 polysaccharide biosynthetic process K06409 - - 0.0000000000005776 74.0
HFD3_k127_4635674_3 Fumarase C C-terminus K01744 - 4.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 524.0
HFD3_k127_4635674_4 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00334,K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 515.0
HFD3_k127_4635674_5 Belongs to the DegT DnrJ EryC1 family K02805 - 2.6.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 476.0
HFD3_k127_4635674_6 Fibronectin type 3 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004419 484.0
HFD3_k127_4635674_7 formate dehydrogenase (NAD+) activity K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 413.0
HFD3_k127_4635674_8 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 291.0
HFD3_k127_4635674_9 COGs COG0463 Glycosyltransferase involved in cell wall biogenesis K10012 - 2.4.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006126 294.0
HFD3_k127_4650046_0 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 555.0
HFD3_k127_4650046_1 protein kinase related protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005598 509.0
HFD3_k127_4650046_2 Iron-containing alcohol dehydrogenase K00001,K13954 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009083 382.0
HFD3_k127_4650046_3 beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 332.0
HFD3_k127_4650046_4 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 312.0
HFD3_k127_4650046_5 Prolyl oligopeptidase family - - - 0.0000000000000000000000000008949 124.0
HFD3_k127_4650046_6 - - - - 0.0000000000001473 78.0
HFD3_k127_4673438_0 Cytochrome c - - - 0.0 1088.0
HFD3_k127_4673438_1 MacB-like periplasmic core domain - - - 2.383e-279 885.0
HFD3_k127_4673438_10 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005017 566.0
HFD3_k127_4673438_11 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000902 455.0
HFD3_k127_4673438_12 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 448.0
HFD3_k127_4673438_13 Domains REC, sigma54 interaction, HTH8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009469 445.0
HFD3_k127_4673438_14 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 477.0
HFD3_k127_4673438_15 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 363.0
HFD3_k127_4673438_16 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 347.0
HFD3_k127_4673438_17 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 319.0
HFD3_k127_4673438_18 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006437 304.0
HFD3_k127_4673438_19 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 297.0
HFD3_k127_4673438_2 CHASE3 domain - - - 5.903e-240 758.0
HFD3_k127_4673438_20 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000003095 247.0
HFD3_k127_4673438_21 oxidoreductase activity, acting on diphenols and related substances as donors K02636,K03886 - 1.10.9.1 0.000000000000000000000000000000000000000000000000000000000000000000005213 242.0
HFD3_k127_4673438_22 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000001024 238.0
HFD3_k127_4673438_23 Belongs to the ABC transporter superfamily K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000001149 230.0
HFD3_k127_4673438_24 Biotin-lipoyl like K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000001532 245.0
HFD3_k127_4673438_25 Polysaccharide lyase family 4, domain II - - - 0.0000000000000000000000000000000000000000000000000000000000000003928 230.0
HFD3_k127_4673438_26 COG2931 RTX toxins and related Ca2 -binding - - - 0.000000000000000000000000000000000000000000000000000000000001143 241.0
HFD3_k127_4673438_27 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000000000004339 212.0
HFD3_k127_4673438_28 deoxyhypusine monooxygenase activity K00627,K02160,K07402 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000001499 213.0
HFD3_k127_4673438_29 - K19693 - - 0.000000000000000000000000000000000000000000000000000002594 214.0
HFD3_k127_4673438_3 efflux transmembrane transporter activity - - - 1.241e-231 741.0
HFD3_k127_4673438_30 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000005923 201.0
HFD3_k127_4673438_31 Putative zinc-finger - - - 0.000000000000000000000000000000000000000000000000002366 196.0
HFD3_k127_4673438_32 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000005788 188.0
HFD3_k127_4673438_33 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000009361 186.0
HFD3_k127_4673438_34 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000232 197.0
HFD3_k127_4673438_35 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000383 182.0
HFD3_k127_4673438_36 4Fe-4S binding domain K00395,K02572,K03616 - 1.8.99.2 0.00000000000000000000000000000000000000000000007072 171.0
HFD3_k127_4673438_37 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000002783 183.0
HFD3_k127_4673438_38 Universal stress protein family - - - 0.00000000000000000000000000000000000000005042 165.0
HFD3_k127_4673438_39 SCO1/SenC K07152,K08976 - - 0.00000000000000000000000000000000000004221 147.0
HFD3_k127_4673438_4 - - - - 1.427e-219 704.0
HFD3_k127_4673438_40 Cytochrome oxidase assembly protein K02259 - - 0.000000000000000000000000000000000000386 153.0
HFD3_k127_4673438_41 Caspase domain - - - 0.000000000000000000000000000000000609 152.0
HFD3_k127_4673438_42 amino acid activation for nonribosomal peptide biosynthetic process K03641,K20276 - - 0.000000000000000000000000000000001336 152.0
HFD3_k127_4673438_43 Helix-turn-helix XRE-family like proteins K21498 - - 0.0000000000000000000000000000002362 126.0
HFD3_k127_4673438_44 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000584 119.0
HFD3_k127_4673438_45 AMP binding K06149 - - 0.00000000000000000000000004938 115.0
HFD3_k127_4673438_46 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000002836 106.0
HFD3_k127_4673438_47 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000001406 103.0
HFD3_k127_4673438_48 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000134 100.0
HFD3_k127_4673438_5 efflux transmembrane transporter activity - - - 7.819e-203 662.0
HFD3_k127_4673438_50 RelE-like toxin of type II toxin-antitoxin system HigB - - - 0.000000000000000006903 83.0
HFD3_k127_4673438_52 Yip1 domain - - - 0.00000000000000007492 91.0
HFD3_k127_4673438_53 Glutaredoxin-like domain (DUF836) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000001521 71.0
HFD3_k127_4673438_54 PFAM Copper resistance D K07245 - - 0.00000000003291 71.0
HFD3_k127_4673438_55 FG-GAP repeat - - - 0.0000000002006 76.0
HFD3_k127_4673438_56 COG3209 Rhs family protein - - - 0.0000000004067 69.0
HFD3_k127_4673438_57 - - - - 0.0005673 46.0
HFD3_k127_4673438_6 Vault protein inter-alpha-trypsin domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 635.0
HFD3_k127_4673438_7 Belongs to the heme-copper respiratory oxidase family K02274 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 621.0
HFD3_k127_4673438_8 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 610.0
HFD3_k127_4673438_9 Fibronectin type 3 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 581.0
HFD3_k127_4702386_0 C-terminus of AA_permease K03294 - - 1.545e-224 704.0
HFD3_k127_4702386_1 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 610.0
HFD3_k127_4702386_2 PFAM Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 595.0
HFD3_k127_4702386_3 Catalyzes the synthesis of activated sulfate K00390,K00860 - 1.8.4.10,1.8.4.8,2.7.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000002731 257.0
HFD3_k127_4702386_4 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000004043 231.0
HFD3_k127_4705320_0 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006797 490.0
HFD3_k127_4705320_1 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006115 419.0
HFD3_k127_4705320_2 COG0644 Dehydrogenases (flavoproteins) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 411.0
HFD3_k127_4705320_3 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 330.0
HFD3_k127_4705320_4 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 316.0
HFD3_k127_4705320_5 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.0000000000000000000000000000000000000000000000000000000000000001364 228.0
HFD3_k127_4705320_6 COG0635 Coproporphyrinogen III oxidase and related Fe-S - - - 0.0000000000000000000000000000000000000000000000000000008523 197.0
HFD3_k127_4705320_7 - - - - 0.0000000000000000000000001636 111.0
HFD3_k127_4705320_8 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000057 53.0
HFD3_k127_47264_0 Heat shock 70 kDa protein K04043 - - 2.489e-232 735.0
HFD3_k127_47264_1 Aconitase family (aconitate hydratase) K01703 - 4.2.1.33,4.2.1.35 7.258e-229 716.0
HFD3_k127_47264_10 Transcriptional regulator, LysR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005741 398.0
HFD3_k127_47264_11 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007366 402.0
HFD3_k127_47264_12 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009795 385.0
HFD3_k127_47264_13 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006202 321.0
HFD3_k127_47264_14 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006058 318.0
HFD3_k127_47264_15 B-1 B cell differentiation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 307.0
HFD3_k127_47264_16 COG0438 Glycosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 297.0
HFD3_k127_47264_17 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003872 271.0
HFD3_k127_47264_18 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.000000000000000000000000000000007798 136.0
HFD3_k127_47264_19 iron-sulfur cluster assembly K07400 - - 0.00000000000000000000000000000001559 134.0
HFD3_k127_47264_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00520 - 1.16.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004749 598.0
HFD3_k127_47264_20 Cytochrome c - - - 0.00000000000007224 83.0
HFD3_k127_47264_22 Periplasmic or secreted lipoprotein - - - 0.0000000000002525 79.0
HFD3_k127_47264_23 Protein of unknown function (DUF1573) - - - 0.000000000211 70.0
HFD3_k127_47264_24 Response regulator, receiver - - - 0.0000002338 61.0
HFD3_k127_47264_25 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.00001323 47.0
HFD3_k127_47264_26 Evidence 5 No homology to any previously reported sequences K07156,K07245,K14166 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000936 54.0
HFD3_k127_47264_27 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0003546 51.0
HFD3_k127_47264_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005181 523.0
HFD3_k127_47264_4 DinB superfamily K18912 - 1.14.99.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 517.0
HFD3_k127_47264_5 PQQ-like domain K00114 - 1.1.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 496.0
HFD3_k127_47264_6 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 486.0
HFD3_k127_47264_7 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 460.0
HFD3_k127_47264_8 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 457.0
HFD3_k127_47264_9 N-terminal domain of oxidoreductase K07119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 445.0
HFD3_k127_4775319_0 Serine Threonine protein kinase - - - 0.0 1170.0
HFD3_k127_4775319_1 gluconolactonase activity K01053 - 3.1.1.17 2.328e-194 621.0
HFD3_k127_4775319_2 Sigma-54 interaction domain K15836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 446.0
HFD3_k127_4775319_3 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 330.0
HFD3_k127_4775319_4 Cupin 2, conserved barrel domain protein K11477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 321.0
HFD3_k127_4775319_5 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 327.0
HFD3_k127_4775319_6 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000000004018 183.0
HFD3_k127_4775319_7 Haem-degrading K11477 - - 0.0000000000000000000000000000000000003241 146.0
HFD3_k127_4775319_8 Glycogen recognition site of AMP-activated protein kinase - - - 0.0000000000009745 81.0
HFD3_k127_4810779_0 Alpha-2-Macroglobulin K06894 - - 2.399e-243 801.0
HFD3_k127_4810779_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009074 393.0
HFD3_k127_4810779_10 Caspase domain - - - 0.0000000000004087 83.0
HFD3_k127_4810779_11 Involved in the TonB-independent uptake of proteins K03641 - - 0.000000001789 70.0
HFD3_k127_4810779_12 Glycosyl transferase, family 2 K20444 - - 0.0004209 53.0
HFD3_k127_4810779_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 347.0
HFD3_k127_4810779_3 FES K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000006011 199.0
HFD3_k127_4810779_4 Protein of unknown function (DUF1175) K09934 - - 0.0000000000000000000000000000000000000000000000000007398 194.0
HFD3_k127_4810779_5 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000000000000000000000000000000000001579 153.0
HFD3_k127_4810779_6 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.0000000000000000000000000000009831 127.0
HFD3_k127_4810779_7 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.00000000000000000000000002574 113.0
HFD3_k127_4810779_8 - - - - 0.000000000000000004176 92.0
HFD3_k127_4810779_9 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.000000000000001959 78.0
HFD3_k127_4816023_0 Beta-lactamase - - - 2.182e-198 626.0
HFD3_k127_4816023_1 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 632.0
HFD3_k127_4816023_2 gluconolactonase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 473.0
HFD3_k127_4816023_3 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 362.0
HFD3_k127_4816023_4 DinB family - - - 0.0000000000000000000000000000000000001628 145.0
HFD3_k127_4816023_5 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000003681 105.0
HFD3_k127_4848934_0 Sodium:solute symporter family - - - 7.208e-250 784.0
HFD3_k127_4848934_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 614.0
HFD3_k127_4848934_10 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007486 443.0
HFD3_k127_4848934_11 carboxylic ester hydrolase activity K00433 - 1.11.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 432.0
HFD3_k127_4848934_12 dioxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 434.0
HFD3_k127_4848934_13 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 425.0
HFD3_k127_4848934_14 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 415.0
HFD3_k127_4848934_15 Associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 395.0
HFD3_k127_4848934_16 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 368.0
HFD3_k127_4848934_17 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 368.0
HFD3_k127_4848934_18 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 355.0
HFD3_k127_4848934_19 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009489 357.0
HFD3_k127_4848934_2 cytochrome p450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 584.0
HFD3_k127_4848934_20 Predicted membrane protein (DUF2238) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 329.0
HFD3_k127_4848934_21 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 330.0
HFD3_k127_4848934_22 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 328.0
HFD3_k127_4848934_23 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004944 306.0
HFD3_k127_4848934_24 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003646 312.0
HFD3_k127_4848934_25 Cysteine-rich domain K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 295.0
HFD3_k127_4848934_26 PFAM GTP cyclohydrolase I Nitrile oxidoreductase K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000002572 255.0
HFD3_k127_4848934_27 Response receiver-modulated cyclic diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001131 264.0
HFD3_k127_4848934_28 modulates the activities of several proteins which are inactive in their K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000003081 240.0
HFD3_k127_4848934_29 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000002748 236.0
HFD3_k127_4848934_3 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 580.0
HFD3_k127_4848934_30 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000065 216.0
HFD3_k127_4848934_31 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.000000000000000000000000000000000000000000000000000000000003456 221.0
HFD3_k127_4848934_32 protein phosphatase 2C domain protein K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000186 218.0
HFD3_k127_4848934_33 Aminoacyl-tRNA editing domain - - - 0.000000000000000000000000000000000000000000000000001888 187.0
HFD3_k127_4848934_34 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000001372 185.0
HFD3_k127_4848934_35 - - - - 0.0000000000000000000000000000000000000001263 153.0
HFD3_k127_4848934_36 diguanylate cyclase - - - 0.000000000000000000000000000000000000000221 169.0
HFD3_k127_4848934_38 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000227 154.0
HFD3_k127_4848934_39 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000002821 139.0
HFD3_k127_4848934_4 Cys/Met metabolism PLP-dependent enzyme K01760,K17217 - 4.4.1.1,4.4.1.2,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 522.0
HFD3_k127_4848934_40 LUD domain K00782 - - 0.00000000000000000000000000008195 124.0
HFD3_k127_4848934_41 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000000000000000271 121.0
HFD3_k127_4848934_42 ABC-2 family transporter protein - - - 0.00000000000000000000000003108 118.0
HFD3_k127_4848934_43 PFAM AMP-dependent synthetase and ligase - - - 0.00000000000000000000000008875 124.0
HFD3_k127_4848934_44 Bacterial DNA-binding protein K03530 - - 0.0000000000000000000000003438 111.0
HFD3_k127_4848934_45 phosphorelay signal transduction system K02488,K04757 - 2.7.11.1,2.7.7.65 0.0000000000000000000000007452 111.0
HFD3_k127_4848934_46 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000003399 97.0
HFD3_k127_4848934_47 DinB superfamily - - - 0.0000000000000001144 86.0
HFD3_k127_4848934_48 bacterial OsmY and nodulation domain - - - 0.0000000000000005664 85.0
HFD3_k127_4848934_49 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.0000000000002023 81.0
HFD3_k127_4848934_5 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008854 494.0
HFD3_k127_4848934_51 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000001038 65.0
HFD3_k127_4848934_52 - - - - 0.000000003505 66.0
HFD3_k127_4848934_54 Belongs to the ompA family - - - 0.0000007392 59.0
HFD3_k127_4848934_55 AntiSigma factor - - - 0.000004788 57.0
HFD3_k127_4848934_56 - - - - 0.00008374 51.0
HFD3_k127_4848934_57 Domain of unknown function (DUF4440) - - - 0.0001442 49.0
HFD3_k127_4848934_6 LUD domain K18929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 466.0
HFD3_k127_4848934_7 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 454.0
HFD3_k127_4848934_8 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 449.0
HFD3_k127_4848934_9 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 441.0
HFD3_k127_4871188_0 repeat protein - - - 5.957e-288 897.0
HFD3_k127_4871188_1 PFAM 4Fe-4S binding domain - - - 6.198e-204 643.0
HFD3_k127_4871188_2 Domain of unknown function (DUF305) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004169 253.0
HFD3_k127_4871188_3 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000001306 224.0
HFD3_k127_4871188_4 - - - - 0.000000000000000000000000000000000000000000000000000119 191.0
HFD3_k127_4871188_5 SpoIIAA-like - - - 0.000000000000000000000000000000000000000001843 161.0
HFD3_k127_4871188_6 PFAM helix-turn-helix HxlR type - - - 0.00000000000000000000000000000000008363 136.0
HFD3_k127_4871188_7 Protein of unknown function (DUF2905) - - - 0.00000000000000001277 84.0
HFD3_k127_4871188_8 YceI-like domain - - - 0.00000000005319 63.0
HFD3_k127_4890250_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 1.161e-219 697.0
HFD3_k127_4890250_1 Phosphoglycerate kinase K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005061 488.0
HFD3_k127_4890250_10 Dihydrodipicolinate synthase N-acetylneuraminate lyase K01714 - 4.3.3.7 0.00004701 55.0
HFD3_k127_4890250_2 TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008806 480.0
HFD3_k127_4890250_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003035 277.0
HFD3_k127_4890250_4 NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001801 298.0
HFD3_k127_4890250_5 Cupin domain - - - 0.000000000000000000000000000000000000000000000000003984 184.0
HFD3_k127_4890250_6 PFAM OsmC family protein K07397 - - 0.000000000000000000000000000001245 126.0
HFD3_k127_4890250_7 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000001801 103.0
HFD3_k127_4890250_8 PFAM Preprotein translocase SecG subunit K03075 - - 0.0000000009344 66.0
HFD3_k127_4890250_9 DNA-binding transcriptional activator of the SARP family - - - 0.0000006803 62.0
HFD3_k127_4908792_0 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009717 614.0
HFD3_k127_4908792_1 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 619.0
HFD3_k127_4908792_10 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000002152 263.0
HFD3_k127_4908792_11 - - - - 0.00000000000000000000000000000000000000005057 157.0
HFD3_k127_4908792_12 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000002693 150.0
HFD3_k127_4908792_13 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.000000000000000000000001142 104.0
HFD3_k127_4908792_14 AhpC TSA family - - - 0.000000006635 61.0
HFD3_k127_4908792_15 Redoxin - - - 0.00000002929 58.0
HFD3_k127_4908792_16 Protein of unknown function (DUF2889) - - - 0.000001946 57.0
HFD3_k127_4908792_2 metal ion transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 572.0
HFD3_k127_4908792_3 alcohol dehydrogenase K13979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004664 540.0
HFD3_k127_4908792_4 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009379 538.0
HFD3_k127_4908792_5 Thiamine pyrophosphate enzyme, central domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007824 477.0
HFD3_k127_4908792_6 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008655 405.0
HFD3_k127_4908792_7 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008419 322.0
HFD3_k127_4908792_8 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 303.0
HFD3_k127_4908792_9 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002242 271.0
HFD3_k127_4930959_0 His Kinase A (phosphoacceptor) domain K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 567.0
HFD3_k127_4930959_1 Oxidoreductase family, C-terminal alpha beta domain K00118,K13020 - 1.1.1.335,1.1.99.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008703 484.0
HFD3_k127_4930959_10 - - - - 0.0004188 49.0
HFD3_k127_4930959_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 441.0
HFD3_k127_4930959_3 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 368.0
HFD3_k127_4930959_5 Protein of unknown function (DUF1003) - - - 0.0000000000000000000000000000000000000000000000007829 181.0
HFD3_k127_4930959_6 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000002808 153.0
HFD3_k127_4930959_7 Protein of unknown function (DUF3309) - - - 0.00000000000000001593 83.0
HFD3_k127_4930959_8 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000001543 61.0
HFD3_k127_4930959_9 Rhodanese domain protein - - - 0.00000001019 57.0
HFD3_k127_5003858_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 3.897e-214 681.0
HFD3_k127_5003858_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007424 338.0
HFD3_k127_5127620_0 alpha-L-arabinofuranosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 589.0
HFD3_k127_5127620_1 PFAM GCN5-related N-acetyltransferase K03824 - - 0.000000000000000000000000000000000000000000000000003303 188.0
HFD3_k127_5127620_2 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000173 47.0
HFD3_k127_5219427_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K17050 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0042126,GO:0043436,GO:0043546,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0097159,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 0.0 1796.0
HFD3_k127_5219427_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.0 1096.0
HFD3_k127_5219427_10 Major Facilitator Superfamily K02575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008226 402.0
HFD3_k127_5219427_11 nitrite transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 357.0
HFD3_k127_5219427_12 phosphohydrolases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 340.0
HFD3_k127_5219427_13 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 341.0
HFD3_k127_5219427_14 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006279 321.0
HFD3_k127_5219427_15 4 iron, 4 sulfur cluster binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 305.0
HFD3_k127_5219427_16 Diacylglycerol kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005172 294.0
HFD3_k127_5219427_17 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000072 310.0
HFD3_k127_5219427_18 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002559 263.0
HFD3_k127_5219427_19 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001866 253.0
HFD3_k127_5219427_2 4Fe-4S dicluster domain K00184 - - 1.243e-274 875.0
HFD3_k127_5219427_20 - - - - 0.000000000000000000000000000000000000000000000000000000000000002779 229.0
HFD3_k127_5219427_21 nitrate reductase activity K00370,K00374,K02575 GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006950,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009628,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0036293,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0055114,GO:0070469,GO:0070470,GO:0070482,GO:0071944,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000000392 221.0
HFD3_k127_5219427_22 oxidoreductase activity, acting on diphenols and related substances as donors - - - 0.000000000000000000000000000000000000000000000000000000000002199 215.0
HFD3_k127_5219427_23 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.0000000000000000000000000000000000000000000000000000000000886 213.0
HFD3_k127_5219427_24 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000006578 196.0
HFD3_k127_5219427_25 cell septum assembly - - - 0.0000000000000000000000000000000000000000000000003261 199.0
HFD3_k127_5219427_26 Cytochrome c - - - 0.000000000000000000000000000000000000000000004992 173.0
HFD3_k127_5219427_27 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000000000000478 166.0
HFD3_k127_5219427_28 cytochrome c - - - 0.000000000000000000000000000000000000000005219 160.0
HFD3_k127_5219427_29 Hemerythrin hhe cation binding - - - 0.000000000000000000000000000000001849 139.0
HFD3_k127_5219427_3 nitrate reductase beta subunit K00371 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0033554,GO:0042126,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 1.109e-232 729.0
HFD3_k127_5219427_30 - - - - 0.0000000000000000000000000000009216 131.0
HFD3_k127_5219427_31 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000002065 120.0
HFD3_k127_5219427_32 Protein of unknown function (DUF1440) K08996 - - 0.000000000000000000000000000256 122.0
HFD3_k127_5219427_33 Plasmid stabilization - - - 0.0000000000000000000000000009688 113.0
HFD3_k127_5219427_34 - - - - 0.00000000000000000003638 92.0
HFD3_k127_5219427_35 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.0000000000000000001413 96.0
HFD3_k127_5219427_36 - K05594 - - 0.000000000000000002437 90.0
HFD3_k127_5219427_37 - - - - 0.00000000000000002211 86.0
HFD3_k127_5219427_38 - - - - 0.0000000000000003139 85.0
HFD3_k127_5219427_39 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.00000000000003962 78.0
HFD3_k127_5219427_4 Polysulphide reductase, NrfD K00185 - - 1.458e-214 675.0
HFD3_k127_5219427_40 Belongs to the TPP enzyme family K00156 - 1.2.5.1 0.0000000002295 64.0
HFD3_k127_5219427_41 Two component transcriptional regulator, winged helix family K02483 - - 0.00000000263 67.0
HFD3_k127_5219427_5 DNA polymerase beta thumb K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 582.0
HFD3_k127_5219427_6 Voltage-dependent anion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004165 545.0
HFD3_k127_5219427_7 Seven times multi-haem cytochrome CxxCH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 499.0
HFD3_k127_5219427_8 nitrite transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 463.0
HFD3_k127_5219427_9 dna ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 425.0
HFD3_k127_5222076_0 O-Antigen ligase K02847 - - 0.00000000000000000000000000000000000000000000004167 187.0
HFD3_k127_5222076_2 SLBB domain K01991 - - 0.0000000000000000000000000000000000572 148.0
HFD3_k127_5222076_3 lipopolysaccharide metabolic process K08309,K19804 - - 0.000000000000000003082 98.0
HFD3_k127_5222076_4 G-rich domain on putative tyrosine kinase - - - 0.000000000000001374 89.0
HFD3_k127_5222076_5 Phospholipid methyltransferase K21310 - 2.1.1.334 0.0000002285 57.0
HFD3_k127_5250085_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 8.756e-205 672.0
HFD3_k127_5250085_1 POT family K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 524.0
HFD3_k127_5250085_10 Protein of unknown function (DUF1573) - - - 0.0001056 46.0
HFD3_k127_5250085_11 Belongs to the 'phage' integrase family - - - 0.0001769 49.0
HFD3_k127_5250085_2 Di-haem oxidoreductase, putative peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005013 343.0
HFD3_k127_5250085_3 PFAM Aminotransferase class I and II K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 321.0
HFD3_k127_5250085_4 Amino acid transporter K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 308.0
HFD3_k127_5250085_5 carboxylic acid catabolic process - - - 0.00000000000000000000000000000000000000000000000002111 194.0
HFD3_k127_5250085_6 PQQ enzyme repeat - - - 0.000000000000000000000000000005552 134.0
HFD3_k127_5250085_7 Smr domain - - - 0.0000000000000000000000000005284 119.0
HFD3_k127_5250085_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.0000000000000000000009223 110.0
HFD3_k127_5317763_0 TonB-dependent receptor - - - 1.212e-208 688.0
HFD3_k127_5317763_1 Ribosomal protein S1 K02945 - - 4.199e-206 659.0
HFD3_k127_5317763_10 Predicted integral membrane protein (DUF2270) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002407 255.0
HFD3_k127_5317763_11 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000000000000007689 205.0
HFD3_k127_5317763_12 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000006834 180.0
HFD3_k127_5317763_13 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000005111 145.0
HFD3_k127_5317763_2 FAD dependent oxidoreductase K00303,K21061 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005307 495.0
HFD3_k127_5317763_3 Fungal trichothecene efflux pump (TRI12) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006132 439.0
HFD3_k127_5317763_4 PFAM Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 425.0
HFD3_k127_5317763_5 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008634 403.0
HFD3_k127_5317763_6 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 413.0
HFD3_k127_5317763_7 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 318.0
HFD3_k127_5317763_8 PFAM peptidase S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005737 265.0
HFD3_k127_5317763_9 Molybdopterin oxidoreductase Fe4S4 domain K08357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001473 272.0
HFD3_k127_5442041_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 1.521e-210 665.0
HFD3_k127_5442041_1 Peptidase family S58 K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 467.0
HFD3_k127_5442041_2 Peptidase M1, membrane alanine aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 375.0
HFD3_k127_5442041_3 Transporter-associated region K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 363.0
HFD3_k127_5442041_4 PFAM Basic membrane lipoprotein K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 357.0
HFD3_k127_5442041_5 PFAM Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000005404 221.0
HFD3_k127_5442041_6 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000653 201.0
HFD3_k127_5442041_7 - - - - 0.0000000000000000000000000000000000000000000000000243 182.0
HFD3_k127_5442041_8 Asparaginase K01444 - 3.5.1.26 0.0000000000000000000004486 99.0
HFD3_k127_5463024_0 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000001348 248.0
HFD3_k127_5463024_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000002827 214.0
HFD3_k127_5463024_2 Protein kinase domain K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.0000000000000000000000000000000000000000000000009207 198.0
HFD3_k127_5466292_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564 2.7.4.1 2.024e-238 756.0
HFD3_k127_5466292_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.12e-223 712.0
HFD3_k127_5466292_2 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 580.0
HFD3_k127_5466292_3 Domain of unknown function (DUF3471) K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 528.0
HFD3_k127_5466292_4 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006616 437.0
HFD3_k127_5466292_5 ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004552 274.0
HFD3_k127_5466292_6 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000001296 242.0
HFD3_k127_5466292_7 Forkhead associated domain - - - 0.0000000000000000000000000001832 129.0
HFD3_k127_5466292_8 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000009169 92.0
HFD3_k127_5491860_0 PrkA AAA domain protein K07180 - - 9.426e-300 932.0
HFD3_k127_5491860_1 Elongation factor G, domain IV K02355 - - 1.326e-245 777.0
HFD3_k127_5491860_10 Penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 406.0
HFD3_k127_5491860_11 Peptidase family M50 K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 327.0
HFD3_k127_5491860_12 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 291.0
HFD3_k127_5491860_13 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001741 286.0
HFD3_k127_5491860_14 enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000003221 236.0
HFD3_k127_5491860_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000009313 229.0
HFD3_k127_5491860_16 Metalloenzyme superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000001233 226.0
HFD3_k127_5491860_17 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000001819 217.0
HFD3_k127_5491860_18 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02527,K02841,K02843,K12982 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000006632 192.0
HFD3_k127_5491860_19 Soluble NSF attachment protein, SNAP - - - 0.0000000000000000000000000000000000000000000000002338 203.0
HFD3_k127_5491860_2 SMART Elongator protein 3 MiaB NifB - - - 3.894e-234 734.0
HFD3_k127_5491860_20 CHAT domain - - - 0.00000000000000000000000000000000000000000003717 186.0
HFD3_k127_5491860_21 Putative glycolipid-binding K09957 - - 0.0000000000000000000000000000000000000000004642 164.0
HFD3_k127_5491860_22 Phospholipid methyltransferase - - - 0.000000000000000000000000000000000000008456 151.0
HFD3_k127_5491860_23 - - - - 0.0000000000000000000000000000000000011 145.0
HFD3_k127_5491860_24 Protein of unknown function (DUF3108) - - - 0.000000000000000004291 96.0
HFD3_k127_5491860_26 Domain of unknown function (DUF4129) - - - 0.000000000004469 78.0
HFD3_k127_5491860_27 CAAX protease self-immunity - - - 0.00000000001909 74.0
HFD3_k127_5491860_28 pathogenesis K02417,K02519 - - 0.00000000003538 75.0
HFD3_k127_5491860_29 Glycosyltransferase like family - - - 0.000000042 66.0
HFD3_k127_5491860_3 radical SAM domain protein - - - 2.309e-221 698.0
HFD3_k127_5491860_30 BON domain - - - 0.0001993 51.0
HFD3_k127_5491860_4 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 549.0
HFD3_k127_5491860_5 SpoVR like protein K06415 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 550.0
HFD3_k127_5491860_6 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 479.0
HFD3_k127_5491860_7 Belongs to the UPF0229 family K09786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004891 464.0
HFD3_k127_5491860_8 type I phosphodiesterase nucleotide pyrophosphatase - GO:0003674,GO:0003824,GO:0004035,GO:0004346,GO:0005488,GO:0005575,GO:0005623,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008877,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046872,GO:0046914,GO:0050308,GO:0050309,GO:0098519 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 409.0
HFD3_k127_5491860_9 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 397.0
HFD3_k127_5497751_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 3.165e-312 996.0
HFD3_k127_5497751_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 569.0
HFD3_k127_5497751_2 - K00262 - 1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 484.0
HFD3_k127_5497751_3 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 445.0
HFD3_k127_5497751_4 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000001 242.0
HFD3_k127_5497751_5 4-phosphoerythronate dehydrogenase activity K00058,K00122 - 1.1.1.399,1.1.1.95,1.17.1.9 0.0000000000000000000000000000000000000000000000008976 177.0
HFD3_k127_5497751_6 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000001316 169.0
HFD3_k127_5497751_7 PPIC-type PPIASE domain K03769,K03770,K03771,K07533 - 5.2.1.8 0.000000008264 67.0
HFD3_k127_5539377_0 Acyclic terpene utilisation family protein AtuA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 605.0
HFD3_k127_5539377_1 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 400.0
HFD3_k127_5539377_2 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 371.0
HFD3_k127_5539377_3 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000003245 227.0
HFD3_k127_5539377_4 - - - - 0.000000000000000000000000000000000000000000000000000000001496 206.0
HFD3_k127_5539377_5 Phage integrase family - - - 0.00000000000000000000000000000000000000000000000000022 190.0
HFD3_k127_5539377_6 Cytochrome C oxidase, cbb3-type, subunit III K02275 - 1.9.3.1 0.0000000000000000000003731 103.0
HFD3_k127_5539377_7 Belongs to the UPF0337 (CsbD) family - - - 0.0001373 48.0
HFD3_k127_5576111_0 carboxylic acid catabolic process K01187 - 3.2.1.20 1.472e-275 861.0
HFD3_k127_5576111_1 Glycosyltransferase like family 2 - - - 1.514e-203 647.0
HFD3_k127_5576111_10 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 289.0
HFD3_k127_5576111_11 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004351 275.0
HFD3_k127_5576111_12 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004483 261.0
HFD3_k127_5576111_13 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001954 255.0
HFD3_k127_5576111_14 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000414 247.0
HFD3_k127_5576111_15 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000008015 238.0
HFD3_k127_5576111_16 Putative peptidoglycan binding domain K02450 - - 0.00000000000000000000000000000000000000000000000000000000008325 214.0
HFD3_k127_5576111_17 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000004684 188.0
HFD3_k127_5576111_18 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000037 187.0
HFD3_k127_5576111_19 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000738 184.0
HFD3_k127_5576111_2 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008464 461.0
HFD3_k127_5576111_20 protein methyltransferase activity K02687 - - 0.0000000000000000000000000000000000000000000003821 186.0
HFD3_k127_5576111_21 Nucleotidyl transferase - - - 0.0000000000000000000000000000000000000000000006126 177.0
HFD3_k127_5576111_22 ig-like, plexins, transcription factors - - - 0.0000000000000000000000000000000000000000003548 183.0
HFD3_k127_5576111_23 PFAM Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000001846 156.0
HFD3_k127_5576111_24 - - - - 0.0000000000000000000000002482 108.0
HFD3_k127_5576111_25 heme-binding sites - - - 0.000000000000002262 91.0
HFD3_k127_5576111_26 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase - - - 0.000000000007041 77.0
HFD3_k127_5576111_27 guanyl-nucleotide exchange factor activity K01179,K03929,K09612,K12287,K19701,K19702 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005623,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.2.1.4,3.4.11.10,3.4.11.24,3.4.11.6 0.0000000004345 74.0
HFD3_k127_5576111_3 teichoic acid transport K01990,K09689,K09691 - 3.6.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 382.0
HFD3_k127_5576111_4 COG2721 Altronate dehydratase K01685 - 4.2.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008573 383.0
HFD3_k127_5576111_5 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 338.0
HFD3_k127_5576111_6 Alpha-L-fucosidase K01206 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 332.0
HFD3_k127_5576111_7 oxidation-reduction process K00826 GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006694,GO:0006703,GO:0006706,GO:0008150,GO:0008152,GO:0008202,GO:0008210,GO:0008610,GO:0009056,GO:0009058,GO:0009987,GO:0010817,GO:0016042,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0033764,GO:0034754,GO:0042445,GO:0042446,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0047045,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 319.0
HFD3_k127_5576111_8 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 312.0
HFD3_k127_5576111_9 macromolecule localization K01992,K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 291.0
HFD3_k127_55849_0 PFAM Alcohol dehydrogenase GroES-like - - - 2.48e-200 629.0
HFD3_k127_55849_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005593 246.0
HFD3_k127_55849_11 COG0346 Lactoylglutathione lyase and related lyases - - - 0.0000000000000000000000000000000000000000000000000000000000000006165 221.0
HFD3_k127_55849_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000306 231.0
HFD3_k127_55849_13 - - - - 0.000000000000000000000000000000000000000000000000000000002142 213.0
HFD3_k127_55849_14 - - - - 0.0000000000000000000000000000000000000000000000000000002669 207.0
HFD3_k127_55849_15 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000001275 162.0
HFD3_k127_55849_16 SEC-C motif - - - 0.00000000000000000000000000000000000000006273 166.0
HFD3_k127_55849_17 - - - - 0.0000000000000000000000000000000000000004382 149.0
HFD3_k127_55849_18 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000009814 141.0
HFD3_k127_55849_19 lactoylglutathione lyase activity - - - 0.0000000000000000000000000001274 119.0
HFD3_k127_55849_2 sequence-specific DNA binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 521.0
HFD3_k127_55849_20 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000134 124.0
HFD3_k127_55849_21 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000001473 77.0
HFD3_k127_55849_22 Glyoxalase-like domain - - - 0.000000000001518 72.0
HFD3_k127_55849_23 - - - - 0.000000000005528 68.0
HFD3_k127_55849_24 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000009607 47.0
HFD3_k127_55849_25 COGs COG2026 Cytotoxic translational repressor of toxin-antitoxin stability system K06218 - - 0.0009726 42.0
HFD3_k127_55849_3 Oxidoreductase family, C-terminal alpha/beta domain K13020 - 1.1.1.335 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 462.0
HFD3_k127_55849_4 Bacterial protein of unknown function (DUF899) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006867 454.0
HFD3_k127_55849_5 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 384.0
HFD3_k127_55849_6 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004629 359.0
HFD3_k127_55849_7 PFAM Ribonuclease BN-like family K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 332.0
HFD3_k127_55849_8 membrane organization K07277,K09800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005395 353.0
HFD3_k127_55849_9 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001153 244.0
HFD3_k127_5590735_0 Pyrrolo-quinoline quinone - - - 4.793e-227 722.0
HFD3_k127_5590735_1 Peptidase S46 - - - 2.73e-214 687.0
HFD3_k127_5590735_10 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 347.0
HFD3_k127_5590735_11 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 301.0
HFD3_k127_5590735_12 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001501 293.0
HFD3_k127_5590735_13 3-beta hydroxysteroid dehydrogenase isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004019 263.0
HFD3_k127_5590735_14 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000399 252.0
HFD3_k127_5590735_15 lipid kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000003927 245.0
HFD3_k127_5590735_16 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000000000000000000000000000000000000000000000000000000001166 237.0
HFD3_k127_5590735_17 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000647 224.0
HFD3_k127_5590735_18 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000002635 228.0
HFD3_k127_5590735_19 DNA recombination-mediator protein A - - - 0.0000000000000000000000000000000000000000000000000000000000004191 224.0
HFD3_k127_5590735_2 helicase superfamily c-terminal domain K03654 - 3.6.4.12 8.826e-205 654.0
HFD3_k127_5590735_20 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000008951 199.0
HFD3_k127_5590735_21 Phosphoribosyl transferase domain K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000001804 194.0
HFD3_k127_5590735_22 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000001606 187.0
HFD3_k127_5590735_23 Catalyzes the cleavage of the C5-C6 bond of 2-hydroxy-6- oxononadienedioate and 2-hydroxy-6-oxononatrienedioate, a dienol ring fission product of the bacterial meta-cleavage pathway for degradation of phenylpropionic acid K05714 - 3.7.1.14 0.0000000000000000000000000000000000000000000009477 181.0
HFD3_k127_5590735_24 Ankyrin repeat - - - 0.000000000000000000000000000000000000000000001837 172.0
HFD3_k127_5590735_26 Belongs to the HpcH HpaI aldolase family K01644,K08691 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006107,GO:0008150,GO:0008152,GO:0009987,GO:0015977,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0043167,GO:0043169,GO:0043427,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046872,GO:0047777,GO:0050083,GO:0071704 4.1.3.24,4.1.3.25,4.1.3.34 0.0000000000000000000000000000000000000001006 165.0
HFD3_k127_5590735_27 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000006333 158.0
HFD3_k127_5590735_28 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000000000000000003646 135.0
HFD3_k127_5590735_29 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.000000000000000000000000000000001945 136.0
HFD3_k127_5590735_3 Oxidoreductase domain protein - - - 6.048e-204 640.0
HFD3_k127_5590735_30 DEAD DEAH box helicase domain protein K03654 - 3.6.4.12 0.00000000000000000000000000000001836 133.0
HFD3_k127_5590735_31 Lysozyme inhibitor LprI - - - 0.00000000000000000000005738 104.0
HFD3_k127_5590735_32 Uncharacterized ACR, COG1993 K09137 - - 0.00000000003363 68.0
HFD3_k127_5590735_33 - - - - 0.0000008161 60.0
HFD3_k127_5590735_34 - - - - 0.00001605 55.0
HFD3_k127_5590735_35 PFAM ABC transporter K01996 - - 0.0007442 43.0
HFD3_k127_5590735_4 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 525.0
HFD3_k127_5590735_5 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 459.0
HFD3_k127_5590735_6 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 417.0
HFD3_k127_5590735_7 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004952 410.0
HFD3_k127_5590735_8 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 394.0
HFD3_k127_5590735_9 MaoC like domain K14449,K18290 - 4.2.1.148,4.2.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004499 358.0
HFD3_k127_5592897_0 efflux transmembrane transporter activity - - - 2.921e-209 678.0
HFD3_k127_5592897_1 PFAM Sodium Bile acid symporter family K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 545.0
HFD3_k127_5592897_10 Single Cache domain 2 K07647 - 2.7.13.3 0.00000000000000000000000002952 125.0
HFD3_k127_5592897_11 PFAM Peptidase family S41 - - - 0.0000000000000000000005413 106.0
HFD3_k127_5592897_12 - - - - 0.000000000000000000004336 97.0
HFD3_k127_5592897_13 Transcriptional regulatory protein, C terminal - - - 0.0001277 49.0
HFD3_k127_5592897_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 463.0
HFD3_k127_5592897_3 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 350.0
HFD3_k127_5592897_4 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 292.0
HFD3_k127_5592897_5 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001828 259.0
HFD3_k127_5592897_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000005974 218.0
HFD3_k127_5592897_7 PFAM Cache K08738 - - 0.0000000000000000000000000000000000000000000000000000000000003185 233.0
HFD3_k127_5592897_8 lactoylglutathione lyase activity - - - 0.00000000000000000000000000003356 120.0
HFD3_k127_5592897_9 PFAM Cupin 2, conserved barrel - - - 0.00000000000000000000000000022 118.0
HFD3_k127_5615928_0 Amidohydrolase family K01464 - 3.5.2.2 4.911e-208 655.0
HFD3_k127_5615928_1 PFAM Permease for cytosine purines, uracil, thiamine, allantoin K03457 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007097 582.0
HFD3_k127_5615928_10 HEAT repeat - - - 0.00000000000001607 85.0
HFD3_k127_5615928_11 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000064 59.0
HFD3_k127_5615928_12 Belongs to the low molecular weight phosphotyrosine protein phosphatase family - - - 0.0000076 51.0
HFD3_k127_5615928_13 Domain of unknown function (DUF4440) - - - 0.0006535 49.0
HFD3_k127_5615928_2 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008905 448.0
HFD3_k127_5615928_3 carboxylic ester hydrolase activity K03929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 450.0
HFD3_k127_5615928_4 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 409.0
HFD3_k127_5615928_5 H( )-stimulated, divalent metal cation uptake system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 383.0
HFD3_k127_5615928_7 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000001425 226.0
HFD3_k127_5615928_8 abc-type fe3 -hydroxamate transport system, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000004388 188.0
HFD3_k127_5615928_9 - - - - 0.00000000000000000000000000000000000000000004425 179.0
HFD3_k127_5630756_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 1.434e-295 926.0
HFD3_k127_5630756_1 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 8.327e-272 852.0
HFD3_k127_5630756_10 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006893 304.0
HFD3_k127_5630756_11 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003404 284.0
HFD3_k127_5630756_12 Mo-molybdopterin cofactor biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008707 280.0
HFD3_k127_5630756_13 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000003005 259.0
HFD3_k127_5630756_14 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000003188 266.0
HFD3_k127_5630756_15 LytTr DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004811 264.0
HFD3_k127_5630756_16 Protein containing tetrapyrrole methyltransferase domain and MazG-like K02428,K02499 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000001495 262.0
HFD3_k127_5630756_17 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.000000000000000000000000000000000000000000000000000000000000000000000000004509 261.0
HFD3_k127_5630756_18 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000005564 262.0
HFD3_k127_5630756_19 mannose-6-phosphate isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001302 250.0
HFD3_k127_5630756_2 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 1.304e-238 767.0
HFD3_k127_5630756_20 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002708 260.0
HFD3_k127_5630756_21 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001462 249.0
HFD3_k127_5630756_22 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000002713 220.0
HFD3_k127_5630756_23 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000004462 223.0
HFD3_k127_5630756_24 - - - - 0.000000000000000000000000000000000000000000000002687 178.0
HFD3_k127_5630756_25 PFAM carbon monoxide dehydrogenase subunit G K09386 - - 0.000000000000000000000000000000000002593 145.0
HFD3_k127_5630756_26 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000000000000000000000001837 123.0
HFD3_k127_5630756_27 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000374 110.0
HFD3_k127_5630756_28 - - - - 0.00000000000000000000001383 102.0
HFD3_k127_5630756_29 Regulates arginine biosynthesis genes K03402 - - 0.0000000000000000007235 93.0
HFD3_k127_5630756_3 domain protein - - - 1.605e-216 717.0
HFD3_k127_5630756_30 TonB dependent receptor - - - 0.00000000000007426 77.0
HFD3_k127_5630756_31 Domain of unknown function (DUF1844) - - - 0.000000000007128 73.0
HFD3_k127_5630756_32 Protein of unknown function (DUF4230) - - - 0.0000000006353 68.0
HFD3_k127_5630756_35 general secretion pathway protein G K02456 - - 0.0003026 49.0
HFD3_k127_5630756_4 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 595.0
HFD3_k127_5630756_5 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 504.0
HFD3_k127_5630756_6 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 526.0
HFD3_k127_5630756_7 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004119 325.0
HFD3_k127_5630756_8 Belongs to the ATCase OTCase family K00611,K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009552 323.0
HFD3_k127_5630756_9 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 312.0
HFD3_k127_5633775_0 Amylo-alpha-1,6-glucosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 631.0
HFD3_k127_5633775_1 COG1858 Cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 461.0
HFD3_k127_5633775_2 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005626 298.0
HFD3_k127_5633775_3 Glycogen debranching enzyme K18206 - 3.2.1.187 0.00000000000000000000000000000000000000000000000000000000000000000000002334 268.0
HFD3_k127_5633775_4 belongs to the thioredoxin family K03671,K03672 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.1.8 0.0000000000000000000000000000000000000000000000000000215 191.0
HFD3_k127_5633775_5 DinB superfamily - - - 0.00000000000000000005496 96.0
HFD3_k127_5641056_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1416.0
HFD3_k127_5641056_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 8.536e-262 821.0
HFD3_k127_5641056_11 cell adhesion involved in biofilm formation - - - 0.000119 49.0
HFD3_k127_5641056_2 Na dependent nucleoside transporter K03317 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 359.0
HFD3_k127_5641056_3 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000002275 200.0
HFD3_k127_5641056_4 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000007464 215.0
HFD3_k127_5641056_5 lipoprotein localization to outer membrane K02004 - - 0.0000000000000000000000000000000000003504 152.0
HFD3_k127_5641056_6 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000001632 127.0
HFD3_k127_5641056_7 PFAM peptidase M15B and M15C DD-carboxypeptidase VanY endolysin - - - 0.00000000000000000000000000001689 130.0
HFD3_k127_5641056_8 Pkd domain containing protein - - - 0.0000000000000000000000000006877 126.0
HFD3_k127_5641056_9 Uncharacterized conserved protein (COG2071) - - - 0.0000000001056 71.0
HFD3_k127_5719991_0 Isocitrate lyase K01637 GO:0003674,GO:0003824,GO:0004451,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0006102,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046421,GO:0046487,GO:0071704,GO:0072350 4.1.3.1 0.0 1180.0
HFD3_k127_5719991_1 Belongs to the malate synthase family K01638 - 2.3.3.9 1.754e-307 952.0
HFD3_k127_5719991_10 AAA ATPase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 521.0
HFD3_k127_5719991_11 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 442.0
HFD3_k127_5719991_12 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004489 416.0
HFD3_k127_5719991_13 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008585 391.0
HFD3_k127_5719991_14 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004968 359.0
HFD3_k127_5719991_15 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005804 355.0
HFD3_k127_5719991_16 COG3209 Rhs family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009684 335.0
HFD3_k127_5719991_17 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001029 250.0
HFD3_k127_5719991_18 Hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000005661 242.0
HFD3_k127_5719991_19 - - - - 0.0000000000000000000000000000000000000000000000000000009687 205.0
HFD3_k127_5719991_2 Belongs to the carbamoyltransferase HypF family K04656 - - 5.896e-306 958.0
HFD3_k127_5719991_20 Cupin domain - - - 0.0000000000000000000000000000000000000000000000001938 179.0
HFD3_k127_5719991_22 - - - - 0.00000000000000000000000000000000001239 141.0
HFD3_k127_5719991_23 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.0000000000000000000000000002408 115.0
HFD3_k127_5719991_24 Dual specificity phosphatase, catalytic domain - - - 0.00000000000000000000000002494 115.0
HFD3_k127_5719991_25 Putative adhesin - - - 0.0000000000000000000000001115 116.0
HFD3_k127_5719991_26 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000000001206 106.0
HFD3_k127_5719991_27 Transcriptional regulatory protein, C terminal - - - 0.000000000000000638 93.0
HFD3_k127_5719991_28 Alpha beta hydrolase - - - 0.000000000000001967 91.0
HFD3_k127_5719991_29 - - - - 0.000000000000002057 77.0
HFD3_k127_5719991_3 dna ligase - - - 5.776e-233 726.0
HFD3_k127_5719991_30 efflux transmembrane transporter activity K02004 - - 0.0000000000000745 76.0
HFD3_k127_5719991_31 outer membrane protein protective antigen - - - 0.000000006673 68.0
HFD3_k127_5719991_32 - - - - 0.00000002922 62.0
HFD3_k127_5719991_34 MacB-like periplasmic core domain - - - 0.0000008507 51.0
HFD3_k127_5719991_35 efflux transmembrane transporter activity - - - 0.00001427 48.0
HFD3_k127_5719991_4 efflux transmembrane transporter activity - - - 3.327e-229 734.0
HFD3_k127_5719991_5 hydrogenase expression formation protein K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 593.0
HFD3_k127_5719991_6 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005763 607.0
HFD3_k127_5719991_7 ATP dependent DNA ligase C terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008144 559.0
HFD3_k127_5719991_8 AAA ATPase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 539.0
HFD3_k127_5719991_9 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000057 494.0
HFD3_k127_5741567_0 PFAM Type II secretion system protein E K02652 - - 9.299e-214 677.0
HFD3_k127_5741567_1 CHAT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 454.0
HFD3_k127_5741567_10 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000002455 196.0
HFD3_k127_5741567_11 Pfam Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000008589 201.0
HFD3_k127_5741567_12 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000009623 195.0
HFD3_k127_5741567_13 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000007628 181.0
HFD3_k127_5741567_14 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000874 193.0
HFD3_k127_5741567_15 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.0000000000000000000000000000000000000000000008093 176.0
HFD3_k127_5741567_16 Hsp20/alpha crystallin family - - - 0.00000000000000000000000000000000002293 140.0
HFD3_k127_5741567_17 GAF domain-containing protein K08968 - 1.8.4.14 0.0000000000000000000000000000000001018 137.0
HFD3_k127_5741567_18 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000004976 139.0
HFD3_k127_5741567_19 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine - - - 0.0000000000000000000000000000002413 136.0
HFD3_k127_5741567_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009108 405.0
HFD3_k127_5741567_20 Belongs to the GSP D family K02453 - - 0.000000000000000000000000007323 123.0
HFD3_k127_5741567_21 Polymer-forming cytoskeletal - - - 0.000000000000000002531 90.0
HFD3_k127_5741567_24 Protein of unknown function (DUF465) - - - 0.00000002635 61.0
HFD3_k127_5741567_3 Catalyzes the conversion of dihydroorotate to orotate K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 347.0
HFD3_k127_5741567_4 PFAM Type II secretion system F domain K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002677 268.0
HFD3_k127_5741567_5 Metallo-beta-lactamase superfamily K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003223 284.0
HFD3_k127_5741567_6 PFAM Organic solvent tolerance protein K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004107 275.0
HFD3_k127_5741567_7 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000001741 243.0
HFD3_k127_5741567_8 Putative Ig domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001988 251.0
HFD3_k127_5741567_9 Polynucleotide kinase 3 phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000001611 198.0
HFD3_k127_5745730_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 8.112e-276 860.0
HFD3_k127_5745730_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 408.0
HFD3_k127_5745730_2 Required for morphogenesis under gluconeogenic growth conditions - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 329.0
HFD3_k127_5745730_3 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000001144 228.0
HFD3_k127_5745730_4 two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.00000000000000000000000000000000000000000000000000000002141 205.0
HFD3_k127_5745730_5 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.000000000000000000000000000000000000000000000000000001878 201.0
HFD3_k127_5745730_6 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000005008 196.0
HFD3_k127_5745730_7 PFAM von Willebrand factor type A - - - 0.000000000000000000000007523 115.0
HFD3_k127_5745730_8 peptidyl-tyrosine sulfation - - - 0.000000000002739 78.0
HFD3_k127_5814547_0 Asparaginyl-tRNA synthetase K01893 GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 600.0
HFD3_k127_5814547_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 432.0
HFD3_k127_5814547_10 Serine threonine protein kinase K08884 - 2.7.11.1 0.000000000003185 73.0
HFD3_k127_5814547_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007246 402.0
HFD3_k127_5814547_3 Arginase family K01476 - 3.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 361.0
HFD3_k127_5814547_4 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000001306 263.0
HFD3_k127_5814547_5 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003539 246.0
HFD3_k127_5814547_6 LysM domain K08307,K12204 - - 0.000000000000000000000000000000000000000001488 171.0
HFD3_k127_5814547_7 oxidoreductase activity - - - 0.00000000000000000000000000000000000007055 163.0
HFD3_k127_5814547_8 cytokinin biosynthetic process K06966 - 3.2.2.10 0.000000000000000000000000000001442 127.0
HFD3_k127_5814547_9 DNA helicase K03654 - 3.6.4.12 0.0000000000000000621 93.0
HFD3_k127_58829_0 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 389.0
HFD3_k127_58829_1 radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000002964 147.0
HFD3_k127_58829_2 - - - - 0.00000000000000000000000000000001135 140.0
HFD3_k127_58829_3 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00000000000000000000000004475 125.0
HFD3_k127_58829_4 Conserved hypothetical protein (DUF2461) - - - 0.000000000000000000000001356 113.0
HFD3_k127_58829_5 Ankyrin repeats (3 copies) - - - 0.00000000008113 68.0
HFD3_k127_6016901_0 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000567 542.0
HFD3_k127_6016901_1 aromatic amino acid beta-eliminating lyase threonine aldolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 459.0
HFD3_k127_6016901_2 Homoserine dehydrogenase, NAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001645 279.0
HFD3_k127_6016901_3 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000003544 254.0
HFD3_k127_6016901_4 Xylose isomerase-like TIM barrel K06606 - 5.3.99.11 0.0000000000000000000000000000000000000000000000000000000000000000003342 240.0
HFD3_k127_6016901_5 Bacterial transferase hexapeptide (six repeats) K13006,K15673,K15894 - 4.2.1.115 0.0000000000000000000000000000000000000000002197 168.0
HFD3_k127_6016901_6 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000001337 152.0
HFD3_k127_6016901_7 Bacterial sugar transferase K13012 - - 0.0000000000000000000000000000000000007334 140.0
HFD3_k127_6077341_0 C-terminal, D2-small domain, of ClpB protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 373.0
HFD3_k127_6077341_1 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004303 244.0
HFD3_k127_6081392_0 1,4-alpha-glucan branching enzyme activity K00700,K01236 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18,3.2.1.141 5e-324 1011.0
HFD3_k127_6081392_1 Domain of unknown function (DUF3536) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003777 544.0
HFD3_k127_6081392_2 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 496.0
HFD3_k127_6081392_3 AcrB/AcrD/AcrF family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007048 282.0
HFD3_k127_6081392_4 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000458 199.0
HFD3_k127_6081392_5 RDD family - - - 0.00000000000000000000000000000000000000000000002006 180.0
HFD3_k127_6081392_6 WHG domain - - - 0.000000000000000000000000000000000000000001889 164.0
HFD3_k127_6081392_7 positive regulation of translation, ncRNA-mediated K03666 GO:0003674,GO:0003676,GO:0003677,GO:0003681,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016246,GO:0016441,GO:0016458,GO:0017148,GO:0019222,GO:0022607,GO:0022613,GO:0022618,GO:0030423,GO:0031047,GO:0031123,GO:0031124,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032268,GO:0032269,GO:0032270,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0035194,GO:0040029,GO:0040033,GO:0043170,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045974,GO:0045975,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:2000112,GO:2000113 - 0.000000000000000000000002371 106.0
HFD3_k127_612396_0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 472.0
HFD3_k127_612396_1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 405.0
HFD3_k127_612396_2 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001512 278.0
HFD3_k127_612396_3 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000029 138.0
HFD3_k127_6164490_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.141e-216 702.0
HFD3_k127_6164490_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004254 499.0
HFD3_k127_6164490_10 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07667 - - 0.00000000000001771 88.0
HFD3_k127_6164490_11 Tetratricopeptide repeat - - - 0.000572 52.0
HFD3_k127_6164490_2 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007245 402.0
HFD3_k127_6164490_3 Aminotransferase class I and II K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 382.0
HFD3_k127_6164490_4 DHH family K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 316.0
HFD3_k127_6164490_5 Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004324 291.0
HFD3_k127_6164490_6 Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family K05928 - 2.1.1.95 0.00000000000000000000000000000000000000000000000000001056 203.0
HFD3_k127_6164490_7 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000000000000004018 143.0
HFD3_k127_6164490_8 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000202 118.0
HFD3_k127_6164490_9 nuclear chromosome segregation - - - 0.000000000000000000001427 108.0
HFD3_k127_6171876_0 Tricorn protease PDZ domain K08676 - - 0.0 1332.0
HFD3_k127_6171876_1 domain protein - - - 2.062e-222 729.0
HFD3_k127_6171876_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.0000000000000000000000000000000000000000002881 166.0
HFD3_k127_6211462_0 R3H domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006818 612.0
HFD3_k127_6211462_1 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009124 426.0
HFD3_k127_6211462_2 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 342.0
HFD3_k127_6211462_3 Kelch motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 297.0
HFD3_k127_6211462_5 hydrolase family 81 - - - 0.0000000000001614 83.0
HFD3_k127_6211462_6 - - - - 0.00000006541 59.0
HFD3_k127_6211462_7 type II secretion system protein K - - - 0.00002487 57.0
HFD3_k127_6211462_8 Type IV Pilus-assembly protein W K02672 - - 0.00003681 56.0
HFD3_k127_6211462_9 type IV pilus modification protein PilV K02458,K02671 - - 0.0001528 51.0
HFD3_k127_6222630_0 ABC transporter transmembrane region K11085 - - 0.0000000000000000000000000000000000000000000000000001407 188.0
HFD3_k127_6222630_1 O-antigen - - - 0.00000000000000000001602 108.0
HFD3_k127_6222630_2 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000000001371 92.0
HFD3_k127_6222630_3 ABC transporter transmembrane region K11085 - - 0.00000000000000305 77.0
HFD3_k127_6235206_0 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 543.0
HFD3_k127_6235206_1 COG0635 Coproporphyrinogen III oxidase and related Fe-S - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008108 389.0
HFD3_k127_6235206_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002967 326.0
HFD3_k127_6235206_3 protein kinase related protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005509 301.0
HFD3_k127_6235206_4 Protein of unknown function (DUF3311) - - - 0.0000000000008957 71.0
HFD3_k127_6237714_0 Carboxyl transferase domain - - - 3.714e-226 713.0
HFD3_k127_6237714_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 3.966e-218 695.0
HFD3_k127_6237714_10 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 364.0
HFD3_k127_6237714_11 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 305.0
HFD3_k127_6237714_12 cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001744 280.0
HFD3_k127_6237714_13 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000001969 207.0
HFD3_k127_6237714_14 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000007385 172.0
HFD3_k127_6237714_15 BlaR1 peptidase M56 - - - 0.000000000000000000000000000000000000000000005087 185.0
HFD3_k127_6237714_16 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000007169 143.0
HFD3_k127_6237714_17 Penicillinase repressor - - - 0.0000000000000000000000000000000002621 136.0
HFD3_k127_6237714_18 PDZ DHR GLGF domain protein - - - 0.00000000000000000000005023 111.0
HFD3_k127_6237714_19 Putative adhesin - - - 0.0000000000000007859 89.0
HFD3_k127_6237714_2 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 1.023e-213 678.0
HFD3_k127_6237714_20 - - - - 0.000000000000004159 85.0
HFD3_k127_6237714_22 Domain of unknown function (DUF4956) - - - 0.0000000008562 68.0
HFD3_k127_6237714_23 energy transducer activity K03832 - - 0.000000004325 70.0
HFD3_k127_6237714_3 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 563.0
HFD3_k127_6237714_4 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 513.0
HFD3_k127_6237714_5 PFAM Type II secretion system F domain K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 430.0
HFD3_k127_6237714_6 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005194 395.0
HFD3_k127_6237714_7 Carbamoyltransferase C-terminus K00612 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004118 400.0
HFD3_k127_6237714_8 PFAM phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 388.0
HFD3_k127_6237714_9 RmlD substrate binding domain K01784,K02473,K03274,K08678 - 4.1.1.35,5.1.3.2,5.1.3.20,5.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009334 381.0
HFD3_k127_6247481_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1354.0
HFD3_k127_6247481_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 543.0
HFD3_k127_6247481_10 PFAM TonB-dependent Receptor Plug - - - 0.000000000000000000000000000000000000000002962 170.0
HFD3_k127_6247481_11 protein involved in formate dehydrogenase formation K02380 - - 0.000000000000000000000000000000000000009821 154.0
HFD3_k127_6247481_12 Cation transport regulator - - - 0.00000000000000000000000000000000039 136.0
HFD3_k127_6247481_13 - - - - 0.00000000000000000007864 104.0
HFD3_k127_6247481_14 - - - - 0.000000000000000002144 85.0
HFD3_k127_6247481_15 - - - - 0.0000000000000003914 83.0
HFD3_k127_6247481_17 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000001269 89.0
HFD3_k127_6247481_18 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000007797 67.0
HFD3_k127_6247481_19 ErfK YbiS YcfS YnhG family protein - - - 0.000000001026 71.0
HFD3_k127_6247481_2 Formate dehydrogenase N, transmembrane K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 434.0
HFD3_k127_6247481_20 Tfp pilus assembly protein FimV - - - 0.00000001602 67.0
HFD3_k127_6247481_3 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007425 397.0
HFD3_k127_6247481_4 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 332.0
HFD3_k127_6247481_5 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 308.0
HFD3_k127_6247481_6 - - - - 0.0000000000000000000000000000000000000000000000004836 182.0
HFD3_k127_6247481_7 Peptidase family M23 K21472 - - 0.000000000000000000000000000000000000000000000008452 181.0
HFD3_k127_6247481_8 formate dehydrogenase K00127,K08350 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009326,GO:0009987,GO:0015942,GO:0015944,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0020037,GO:0022900,GO:0031224,GO:0031226,GO:0032787,GO:0032991,GO:0033554,GO:0036397,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0051716,GO:0052738,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.00000000000000000000000000000000000000000004986 170.0
HFD3_k127_6247481_9 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000002448 170.0
HFD3_k127_6247668_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1202.0
HFD3_k127_6247668_1 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 532.0
HFD3_k127_6247668_2 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005692 254.0
HFD3_k127_6247668_3 PFAM homoserine dehydrogenase K00003,K12524 - 1.1.1.3,2.7.2.4 0.000000000000000000000000004741 114.0
HFD3_k127_6282459_0 LVIVD repeat - - - 0.0 1373.0
HFD3_k127_6282459_1 Phosphoglucose isomerase K01810,K13810 - 2.2.1.2,5.3.1.9 9.34e-322 1011.0
HFD3_k127_6282459_10 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 467.0
HFD3_k127_6282459_11 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 471.0
HFD3_k127_6282459_12 phosphorelay signal transduction system K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 465.0
HFD3_k127_6282459_13 Belongs to the cysteine synthase cystathionine beta- synthase family K12339,K21148 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113,2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005139 447.0
HFD3_k127_6282459_14 4Fe-4S binding domain K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 396.0
HFD3_k127_6282459_15 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 325.0
HFD3_k127_6282459_16 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 306.0
HFD3_k127_6282459_17 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 304.0
HFD3_k127_6282459_18 ROK family K00886 - 2.7.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001262 280.0
HFD3_k127_6282459_19 6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000806 263.0
HFD3_k127_6282459_2 Belongs to the transketolase family K00615 - 2.2.1.1 4.803e-315 976.0
HFD3_k127_6282459_20 tRNA 3'-trailer cleavage K00784,K01120 - 3.1.26.11,3.1.4.17 0.00000000000000000000000000000000000000000000000000000000000001031 224.0
HFD3_k127_6282459_21 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000004783 223.0
HFD3_k127_6282459_22 FAD binding domain K11472 - - 0.00000000000000000000000000000000000000000000000000000000006852 221.0
HFD3_k127_6282459_23 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000000004061 203.0
HFD3_k127_6282459_24 L-lysine 6-monooxygenase (NADPH-requiring) - - - 0.000000000000000000000000000000000000000000000000000004802 218.0
HFD3_k127_6282459_25 Sucrose-6F-phosphate phosphohydrolase - - - 0.00000000000000000000000000000000000000000000000000001859 198.0
HFD3_k127_6282459_26 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000001305 177.0
HFD3_k127_6282459_27 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000001475 192.0
HFD3_k127_6282459_28 Glucose-6-phosphate dehydrogenase subunit - - - 0.000000000000000000000000000000000000000000003449 179.0
HFD3_k127_6282459_29 JAB/MPN domain K21140 - 3.13.1.6 0.0000000000000000000000000000000000003337 144.0
HFD3_k127_6282459_3 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 2.115e-200 636.0
HFD3_k127_6282459_30 PFAM TonB-dependent Receptor Plug - - - 0.000000000000000000000001208 121.0
HFD3_k127_6282459_31 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000007849 106.0
HFD3_k127_6282459_32 Domain of unknown function (DUF309) K09763 - - 0.0000000000000002702 88.0
HFD3_k127_6282459_33 His Kinase A (phosphoacceptor) domain - - - 0.00000000000007904 79.0
HFD3_k127_6282459_34 12 heme-binding sites - - - 0.0000000000009827 79.0
HFD3_k127_6282459_35 Forkhead associated domain - - - 0.000000005347 66.0
HFD3_k127_6282459_36 PFAM Cytochrome c, bacterial - - - 0.00000001388 64.0
HFD3_k127_6282459_37 FHA domain - - - 0.0000002225 65.0
HFD3_k127_6282459_38 TIGRFAM cytochrome C family protein - - - 0.00002109 56.0
HFD3_k127_6282459_39 PFAM Cytochrome c, bacterial - - - 0.00002786 57.0
HFD3_k127_6282459_4 Mo-molybdopterin cofactor metabolic process K03148,K03636,K21029,K21147 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.73,2.7.7.80,2.8.1.11 3.664e-200 633.0
HFD3_k127_6282459_40 Protein of unknown function (DUF2934) - - - 0.00003034 49.0
HFD3_k127_6282459_5 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 613.0
HFD3_k127_6282459_6 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 591.0
HFD3_k127_6282459_7 sequence-specific DNA binding K01697,K01738 GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363 2.5.1.47,4.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009843 535.0
HFD3_k127_6282459_8 FAD linked oxidase domain protein K00102,K00104 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.2.4,1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008761 503.0
HFD3_k127_6282459_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 494.0
HFD3_k127_6293975_0 Belongs to the binding-protein-dependent transport system permease family K10559,K10561 - - 1.675e-263 830.0
HFD3_k127_6293975_1 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10562 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 605.0
HFD3_k127_6293975_2 beta-galactosidase activity K01190 - 3.2.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 434.0
HFD3_k127_6293975_3 carbohydrate kinase FGGY K00848 - 2.7.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 424.0
HFD3_k127_6293975_4 Belongs to the binding-protein-dependent transport system permease family K10560 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 325.0
HFD3_k127_6293975_5 Oligogalacturonate lyase K01730 - 4.2.2.6 0.000000000000000000004009 98.0
HFD3_k127_6293975_6 Belongs to the glycosyl hydrolase 28 family K19172 - - 0.000001378 53.0
HFD3_k127_6293975_7 Trypsin - GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006091,GO:0006508,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009507,GO:0009526,GO:0009532,GO:0009533,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009579,GO:0009657,GO:0009658,GO:0009765,GO:0009941,GO:0009987,GO:0010206,GO:0015979,GO:0016020,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0019684,GO:0030091,GO:0030163,GO:0031967,GO:0031975,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035,GO:0070011,GO:0071704,GO:0071840,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.000003165 58.0
HFD3_k127_6297440_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007169 563.0
HFD3_k127_6297440_1 Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 488.0
HFD3_k127_6297440_10 - K07164 - - 0.0006697 45.0
HFD3_k127_6297440_2 Alcohol dehydrogenase GroES-like domain K13953,K18382 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 381.0
HFD3_k127_6297440_3 Putative neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 371.0
HFD3_k127_6297440_4 phosphoglucosamine mutase activity K01835,K01840,K15778 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 344.0
HFD3_k127_6297440_5 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409,K03070 GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 336.0
HFD3_k127_6297440_6 Ribosomal RNA adenine dimethylases K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000003687 222.0
HFD3_k127_6297440_7 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000003468 201.0
HFD3_k127_6297440_8 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000001704 189.0
HFD3_k127_6297440_9 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000008018 165.0
HFD3_k127_6309625_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 2.375e-316 989.0
HFD3_k127_6309625_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.116e-297 931.0
HFD3_k127_6309625_10 PhoPQ-activated pathogenicity-related protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006743 488.0
HFD3_k127_6309625_11 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009174 476.0
HFD3_k127_6309625_12 Belongs to the PdxS SNZ family K06215 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008122 431.0
HFD3_k127_6309625_13 Alkyl sulfatase dimerisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007612 436.0
HFD3_k127_6309625_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009228 399.0
HFD3_k127_6309625_15 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008524 391.0
HFD3_k127_6309625_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 372.0
HFD3_k127_6309625_17 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 361.0
HFD3_k127_6309625_18 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 353.0
HFD3_k127_6309625_19 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000049 339.0
HFD3_k127_6309625_2 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 4.383e-274 869.0
HFD3_k127_6309625_20 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004911 355.0
HFD3_k127_6309625_21 Unusual protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 337.0
HFD3_k127_6309625_22 DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 318.0
HFD3_k127_6309625_23 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000622 338.0
HFD3_k127_6309625_24 SNARE associated Golgi protein K01077 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 286.0
HFD3_k127_6309625_25 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005164 279.0
HFD3_k127_6309625_26 Belongs to the folylpolyglutamate synthase family K11754 GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003763 285.0
HFD3_k127_6309625_27 Lysin motif K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002246 285.0
HFD3_k127_6309625_28 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004385 273.0
HFD3_k127_6309625_29 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000004186 254.0
HFD3_k127_6309625_3 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000679 593.0
HFD3_k127_6309625_30 PFAM Phenazine biosynthesis PhzC PhzF protein K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000001103 255.0
HFD3_k127_6309625_31 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001275 249.0
HFD3_k127_6309625_32 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002151 252.0
HFD3_k127_6309625_33 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000001044 240.0
HFD3_k127_6309625_34 tRNA pseudouridine synthase activity K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000004851 237.0
HFD3_k127_6309625_35 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000025 231.0
HFD3_k127_6309625_36 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000003548 227.0
HFD3_k127_6309625_37 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000005372 222.0
HFD3_k127_6309625_38 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000001215 217.0
HFD3_k127_6309625_39 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000112 213.0
HFD3_k127_6309625_4 Gamma-glutamyltranspeptidase K00681 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 562.0
HFD3_k127_6309625_40 helix_turn_helix ASNC type K03719 - - 0.000000000000000000000000000000000000000000000000000000005815 203.0
HFD3_k127_6309625_41 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000006151 201.0
HFD3_k127_6309625_42 PFAM cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000009276 190.0
HFD3_k127_6309625_43 - - - - 0.0000000000000000000000000000000000000000000000001097 185.0
HFD3_k127_6309625_44 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000007978 183.0
HFD3_k127_6309625_45 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000001149 185.0
HFD3_k127_6309625_46 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000000000000000000000000001033 175.0
HFD3_k127_6309625_47 FAD binding domain - - - 0.000000000000000000000000000000000000000000001472 181.0
HFD3_k127_6309625_48 Peptidase family M23 K21471 - - 0.000000000000000000000000000000000000000000824 167.0
HFD3_k127_6309625_49 Methyltransferase domain - - - 0.0000000000000000000000000000000000000001589 159.0
HFD3_k127_6309625_5 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 547.0
HFD3_k127_6309625_50 Calcium/calmodulin dependent protein kinase II association domain - - - 0.0000000000000000000000000000000000002712 149.0
HFD3_k127_6309625_51 Methyltransferase domain - - - 0.0000000000000000000000000000000000005349 153.0
HFD3_k127_6309625_52 PFAM NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000001175 139.0
HFD3_k127_6309625_53 plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000000000005625 136.0
HFD3_k127_6309625_54 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000006064 128.0
HFD3_k127_6309625_55 Tetratricopeptide repeat - - - 0.0000000000000000000000000000006145 141.0
HFD3_k127_6309625_56 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000000007974 124.0
HFD3_k127_6309625_57 AraC-like ligand binding domain - - - 0.000000000000000000000000000001296 128.0
HFD3_k127_6309625_58 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000000000000000000008425 119.0
HFD3_k127_6309625_59 PDZ DHR GLGF domain protein - - - 0.00000000000000000000000003413 121.0
HFD3_k127_6309625_6 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 552.0
HFD3_k127_6309625_60 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000007172 112.0
HFD3_k127_6309625_61 Glycoprotease K14742 - - 0.0000000000000000000000001487 116.0
HFD3_k127_6309625_62 Putative adhesin - - - 0.0000000000000000000000006038 121.0
HFD3_k127_6309625_63 general stress protein - - - 0.0000000000000000000000008546 109.0
HFD3_k127_6309625_64 COGs COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family - - - 0.0000000000000000000000286 115.0
HFD3_k127_6309625_65 lipolytic protein G-D-S-L family - - - 0.00000000000000003702 84.0
HFD3_k127_6309625_66 - - - - 0.0000000005936 68.0
HFD3_k127_6309625_67 - - - - 0.000000005532 59.0
HFD3_k127_6309625_68 Gaf domain K03832 - - 0.00000000718 69.0
HFD3_k127_6309625_69 - - - - 0.000000007223 59.0
HFD3_k127_6309625_7 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 524.0
HFD3_k127_6309625_70 CAAX protease self-immunity - - - 0.00000002167 65.0
HFD3_k127_6309625_71 Protein of unknown function (DUF2911) - - - 0.00000004243 62.0
HFD3_k127_6309625_72 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000005164 64.0
HFD3_k127_6309625_73 PBS lyase HEAT domain protein repeat-containing protein - - - 0.000003051 55.0
HFD3_k127_6309625_76 phosphinothricin N-acetyltransferase activity K03823 - 2.3.1.183 0.00004045 52.0
HFD3_k127_6309625_77 - - - - 0.00004389 46.0
HFD3_k127_6309625_8 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006562 513.0
HFD3_k127_6309625_9 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 489.0
HFD3_k127_63102_0 ATP-dependent DNA helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 580.0
HFD3_k127_63102_1 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K01501 - 3.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 371.0
HFD3_k127_63102_2 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000627 296.0
HFD3_k127_63102_3 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001634 273.0
HFD3_k127_63102_4 isochorismatase - - - 0.0000000000000000000000000000000000000009038 154.0
HFD3_k127_63102_5 Helix-hairpin-helix DNA-binding, class 1 K02347 - - 0.00000000000000000000000001206 115.0
HFD3_k127_63102_6 - - - - 0.00000000000000000000000764 107.0
HFD3_k127_63102_7 - - - - 0.000000000000000009997 97.0
HFD3_k127_63102_8 PBS lyase HEAT-like repeat - - - 0.000000000000007284 84.0
HFD3_k127_63102_9 methyltransferase activity - - - 0.00000000000447 67.0
HFD3_k127_6325816_0 Carboxypeptidase regulatory-like domain - - - 0.0 1069.0
HFD3_k127_6325816_1 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 5.569e-293 910.0
HFD3_k127_6325816_10 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000863 300.0
HFD3_k127_6325816_11 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 292.0
HFD3_k127_6325816_12 Bacterial regulatory proteins, luxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002738 258.0
HFD3_k127_6325816_13 Amidohydrolase K03392,K22213 - 4.1.1.45,4.1.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000004483 261.0
HFD3_k127_6325816_14 Removes 5-oxoproline from various penultimate amino acid residues except L-proline K01304 GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 3.4.19.3 0.00000000000000000000000000000000000000000000000000000000000000000001394 241.0
HFD3_k127_6325816_15 [2Fe-2S] binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002054 224.0
HFD3_k127_6325816_16 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000000000000001396 225.0
HFD3_k127_6325816_17 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000001852 229.0
HFD3_k127_6325816_18 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000002369 164.0
HFD3_k127_6325816_19 endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000004707 144.0
HFD3_k127_6325816_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K00256 - 1.3.99.16 2.015e-260 821.0
HFD3_k127_6325816_20 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000004627 142.0
HFD3_k127_6325816_21 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000008132 138.0
HFD3_k127_6325816_22 peptidylprolyl isomerase K03770 - 5.2.1.8 0.000000000000000000000000000000001919 149.0
HFD3_k127_6325816_23 Transcriptional regulator - - - 0.0000000000000000000000000000001342 128.0
HFD3_k127_6325816_24 competence protein - - - 0.0000000000000000000000000000003863 133.0
HFD3_k127_6325816_25 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000000003986 128.0
HFD3_k127_6325816_26 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000006211 124.0
HFD3_k127_6325816_27 ABC transporter K01990 - - 0.00000000000000000000000000003354 134.0
HFD3_k127_6325816_28 GAF domain - - - 0.0000000000000000000000000001047 125.0
HFD3_k127_6325816_29 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000000001064 112.0
HFD3_k127_6325816_3 Aminotransferase class-V K01556 - 3.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 574.0
HFD3_k127_6325816_30 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000001532 98.0
HFD3_k127_6325816_31 TPR Domain containing protein K12600 - - 0.00000000001746 76.0
HFD3_k127_6325816_32 Protein involved in outer membrane biogenesis K07289 - - 0.00000001074 67.0
HFD3_k127_6325816_33 Protein involved in outer membrane biogenesis K07289 - - 0.00000389 59.0
HFD3_k127_6325816_35 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00008724 54.0
HFD3_k127_6325816_36 PFAM Sporulation and spore germination - - - 0.0006641 50.0
HFD3_k127_6325816_4 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 532.0
HFD3_k127_6325816_5 proline dipeptidase activity K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 427.0
HFD3_k127_6325816_6 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008019 420.0
HFD3_k127_6325816_7 Peptidase M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 377.0
HFD3_k127_6325816_8 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 388.0
HFD3_k127_6325816_9 Deoxyhypusine synthase K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 324.0
HFD3_k127_6332328_0 Polysulphide reductase, NrfD - - - 7.317e-205 647.0
HFD3_k127_6332328_1 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008476 620.0
HFD3_k127_6332328_10 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000003789 74.0
HFD3_k127_6332328_11 CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481,K10126,K10941 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.00002662 48.0
HFD3_k127_6332328_2 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009445 351.0
HFD3_k127_6332328_3 Cytochrome c K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004984 353.0
HFD3_k127_6332328_4 Doubled CXXCH motif (Paired_CXXCH_1) K08354 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 333.0
HFD3_k127_6332328_5 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.000000000000000000000000000000000000000000000001557 199.0
HFD3_k127_6332328_6 - - - - 0.0000000000000000000000000003365 121.0
HFD3_k127_6332328_7 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000002895 119.0
HFD3_k127_6332328_8 Protein of unknown function (DUF433) - - - 0.000000000000000000006076 98.0
HFD3_k127_6332328_9 PFAM cytoplasmic chaperone TorD family protein - - - 0.00000000000000002605 90.0
HFD3_k127_633682_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 346.0
HFD3_k127_633682_1 Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002934 261.0
HFD3_k127_633682_10 - - - - 0.0003248 47.0
HFD3_k127_633682_2 Phage integrase family - - - 0.00000000000000000000000000000001233 136.0
HFD3_k127_633682_3 Patatin-like phospholipase K07001 - - 0.000000000000000001785 96.0
HFD3_k127_633682_4 TOBE domain K02010,K02052 - 3.6.3.30 0.000000000000000004367 87.0
HFD3_k127_633682_6 Helix-turn-helix domain - - - 0.0000008603 53.0
HFD3_k127_633682_7 N-6 DNA Methylase - - - 0.000007168 48.0
HFD3_k127_633682_8 Belongs to the 'phage' integrase family - - - 0.00002086 53.0
HFD3_k127_6346974_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 3.739e-301 947.0
HFD3_k127_6346974_1 Prolyl oligopeptidase family - - - 1.955e-270 850.0
HFD3_k127_6346974_10 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007513 383.0
HFD3_k127_6346974_11 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005188 364.0
HFD3_k127_6346974_12 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 353.0
HFD3_k127_6346974_13 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 321.0
HFD3_k127_6346974_14 Domain of unknown function (DUF3471) K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001457 281.0
HFD3_k127_6346974_15 endonuclease III K01247 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000004803 259.0
HFD3_k127_6346974_16 Protein of unknown function (DUF1385) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002334 252.0
HFD3_k127_6346974_17 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000436 239.0
HFD3_k127_6346974_18 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000001138 235.0
HFD3_k127_6346974_19 Enoyl-CoA hydratase/isomerase K01715,K07537 - 4.2.1.100,4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000005785 230.0
HFD3_k127_6346974_2 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 1.481e-197 629.0
HFD3_k127_6346974_20 PFAM FAD dependent oxidoreductase K00301 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000002567 231.0
HFD3_k127_6346974_21 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000001589 222.0
HFD3_k127_6346974_22 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000000003385 194.0
HFD3_k127_6346974_23 Stage II sporulation protein E K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000001342 187.0
HFD3_k127_6346974_24 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000442 168.0
HFD3_k127_6346974_25 Formiminotransferase domain, N-terminal subdomain K13990 - 2.1.2.5,4.3.1.4 0.000000000000000000000000000000000007573 145.0
HFD3_k127_6346974_26 Uncharacterized conserved protein (DUF2293) - - - 0.00000000000000000000000000000000509 137.0
HFD3_k127_6346974_27 Iron-binding zinc finger CDGSH type - - - 0.0000000000000000000000000003886 123.0
HFD3_k127_6346974_28 50S ribosomal protein L31 K02909 - - 0.00000000000000000000000001092 111.0
HFD3_k127_6346974_29 DUF167 K09131 - - 0.000000000000000000000001741 105.0
HFD3_k127_6346974_3 Tannase and feruloyl esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 593.0
HFD3_k127_6346974_30 PFAM GCN5-related N-acetyltransferase K06976 - - 0.00000000000000000000000329 113.0
HFD3_k127_6346974_31 Protein of unknown function (DUF971) K03593 - - 0.0000000000000000000000143 104.0
HFD3_k127_6346974_32 Virulence factor BrkB K07058 - - 0.00000000000000001857 93.0
HFD3_k127_6346974_33 PFAM heat shock protein DnaJ domain protein K05516 - - 0.0000000000000001476 89.0
HFD3_k127_6346974_34 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000001591 75.0
HFD3_k127_6346974_35 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000002829 73.0
HFD3_k127_6346974_36 YGGT family K02221 - - 0.0000002981 59.0
HFD3_k127_6346974_37 Uncharacterized conserved protein (DUF2293) - - - 0.00003748 50.0
HFD3_k127_6346974_38 DnaJ molecular chaperone homology domain - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0010598,GO:0016020,GO:0031976,GO:0031984,GO:0032991,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035,GO:0098796 - 0.0001356 53.0
HFD3_k127_6346974_4 Pyridine nucleotide-disulphide oxidoreductase K03885,K10716 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008321 593.0
HFD3_k127_6346974_5 PFAM Peptidase M20 K12941 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 574.0
HFD3_k127_6346974_6 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 503.0
HFD3_k127_6346974_7 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 482.0
HFD3_k127_6346974_8 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 451.0
HFD3_k127_6346974_9 PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006099 452.0
HFD3_k127_6349628_0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K07516 - 1.1.1.35 9.098e-275 867.0
HFD3_k127_6349628_1 acyl-CoA dehydrogenase - - - 7.245e-199 637.0
HFD3_k127_6349628_10 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 440.0
HFD3_k127_6349628_11 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 440.0
HFD3_k127_6349628_12 response regulator K02481,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 428.0
HFD3_k127_6349628_13 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K04105,K04110 - 6.2.1.25,6.2.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 411.0
HFD3_k127_6349628_14 two-component system, chemotaxis family, sensor kinase CheA with response regulator domain K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 379.0
HFD3_k127_6349628_15 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 354.0
HFD3_k127_6349628_16 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007139 349.0
HFD3_k127_6349628_17 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 330.0
HFD3_k127_6349628_18 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006090,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019184,GO:0019752,GO:0031974,GO:0032787,GO:0034641,GO:0042398,GO:0043043,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0051186,GO:0051188,GO:0070013,GO:0071704,GO:1901564,GO:1901566,GO:1901576 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 288.0
HFD3_k127_6349628_19 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 295.0
HFD3_k127_6349628_2 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007339 578.0
HFD3_k127_6349628_20 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007857 292.0
HFD3_k127_6349628_21 Histidine kinase K02660,K03406,K11525 - - 0.000000000000000000000000000000000000000000000000000000000000000001882 256.0
HFD3_k127_6349628_22 CheR methyltransferase, all-alpha domain K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000005545 234.0
HFD3_k127_6349628_23 WD40-like Beta Propeller K03641 - - 0.00000000000000000000000000000000000000000000000000000000000001692 231.0
HFD3_k127_6349628_24 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000002699 225.0
HFD3_k127_6349628_25 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000002514 219.0
HFD3_k127_6349628_26 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000002434 212.0
HFD3_k127_6349628_27 PFAM Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000007368 222.0
HFD3_k127_6349628_28 Zn-dependent hydrolase, glyoxylase - - - 0.0000000000000000000000000000000000000000000000000000005288 205.0
HFD3_k127_6349628_29 Bacterial regulatory proteins, tetR family K13770 - - 0.0000000000000000000000000000000000000000000000000131 187.0
HFD3_k127_6349628_3 UDP binding domain K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 550.0
HFD3_k127_6349628_30 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000003176 182.0
HFD3_k127_6349628_31 MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000000000007044 182.0
HFD3_k127_6349628_32 Peptidase M16 domain protein K07263 - - 0.00000000000000000000000000000000000000000002046 179.0
HFD3_k127_6349628_33 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF K07402 - - 0.0000000000000000000000000000000000000007075 158.0
HFD3_k127_6349628_34 PhoQ Sensor - - - 0.00000000000000000000000000000000000000108 171.0
HFD3_k127_6349628_35 PFAM MscS Mechanosensitive ion channel K03442 - - 0.00000000000000000000000000000000000005331 153.0
HFD3_k127_6349628_36 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000000000000000009182 151.0
HFD3_k127_6349628_37 PFAM ResB family protein K07399 - - 0.000000000000000000000000000000000006939 154.0
HFD3_k127_6349628_38 nucleotide catabolic process - - - 0.000000000000000000000000000000000006975 152.0
HFD3_k127_6349628_39 outer membrane lipoprotein carrier protein LolA K03634 - - 0.000000000000000000000000000000000111 143.0
HFD3_k127_6349628_4 Thiolase, C-terminal domain K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 535.0
HFD3_k127_6349628_40 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000007714 143.0
HFD3_k127_6349628_41 PFAM CheW domain protein K03408 - - 0.0000000000000000000000000000005655 129.0
HFD3_k127_6349628_42 Single cache domain 3 - - - 0.00000000000000000000000000009412 129.0
HFD3_k127_6349628_43 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000000000000000000000001623 121.0
HFD3_k127_6349628_44 protein-glutamate methylesterase activity K03412,K03413 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.1.61,3.5.1.44 0.0000000000000000000000000009907 120.0
HFD3_k127_6349628_45 von Willebrand factor, type A K07114 - - 0.000000000000000000000000001408 126.0
HFD3_k127_6349628_46 Response regulator receiver domain K03413 - - 0.00000000000000000000000001446 113.0
HFD3_k127_6349628_47 lytic transglycosylase activity K03194 - - 0.000000000000000000000005474 116.0
HFD3_k127_6349628_48 Chemotaxis protein CheX K03409 - - 0.00000000000000000000002415 105.0
HFD3_k127_6349628_49 Outer membrane lipoprotein - - - 0.000000000000000000000076 108.0
HFD3_k127_6349628_5 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 519.0
HFD3_k127_6349628_50 regulator, PATAN and FRGAF domain-containing - - - 0.0000000000000007413 90.0
HFD3_k127_6349628_51 Phospholipase_D-nuclease N-terminal - - - 0.000000000000001142 80.0
HFD3_k127_6349628_52 MacB-like periplasmic core domain K02004 - - 0.000000000001516 67.0
HFD3_k127_6349628_53 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.00000005622 61.0
HFD3_k127_6349628_54 energy transducer activity K03646,K03832 - - 0.0000001913 62.0
HFD3_k127_6349628_55 Domain of unknown function (DUF4388) - - - 0.0005108 52.0
HFD3_k127_6349628_6 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 508.0
HFD3_k127_6349628_7 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 462.0
HFD3_k127_6349628_8 ABC transporter, solute-binding protein K11069,K11070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 464.0
HFD3_k127_6349628_9 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005358 449.0
HFD3_k127_6349704_0 Beta-L-arabinofuranosidase, GH127 K09955 - - 0.0 1167.0
HFD3_k127_6349704_1 Dipeptidyl peptidase IV (DPP IV) N-terminal region - - - 0.0 1044.0
HFD3_k127_6349704_2 Sortilin, neurotensin receptor 3, - - - 3.682e-315 990.0
HFD3_k127_6349704_3 Belongs to the glycosyl hydrolase 31 family K01187,K01811 - 3.2.1.177,3.2.1.20 3.326e-299 934.0
HFD3_k127_6349704_4 - - - - 1.782e-266 850.0
HFD3_k127_6349704_5 Alpha-L-arabinofuranosidase C-terminal domain K01209 - 3.2.1.55 4.781e-243 759.0
HFD3_k127_6349704_6 Beta-L-arabinofuranosidase, GH127 K09955 - - 7.195e-214 691.0
HFD3_k127_6349704_7 DNA-binding transcription factor activity K02081,K02444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003424 266.0
HFD3_k127_6349704_8 helix_turn_helix, arabinose operon control protein K07506 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004475 256.0
HFD3_k127_6379893_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1273.0
HFD3_k127_6379893_1 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006957 544.0
HFD3_k127_6379893_10 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000079 305.0
HFD3_k127_6379893_11 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 297.0
HFD3_k127_6379893_12 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002219 277.0
HFD3_k127_6379893_13 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002322 273.0
HFD3_k127_6379893_14 Predicted membrane protein (DUF2339) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000484 299.0
HFD3_k127_6379893_15 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000001264 233.0
HFD3_k127_6379893_16 Mechanosensitive ion channel K05802,K22051 - - 0.000000000000000000000000000000000000000000000000000000000000008973 226.0
HFD3_k127_6379893_17 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000000146 198.0
HFD3_k127_6379893_18 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000008874 194.0
HFD3_k127_6379893_19 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000702 155.0
HFD3_k127_6379893_2 succinyl-diaminopimelate desuccinylase activity K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 484.0
HFD3_k127_6379893_20 Predicted membrane protein (DUF2318) - - - 0.0000000000000000000000000000000281 133.0
HFD3_k127_6379893_21 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000001087 132.0
HFD3_k127_6379893_22 - - - - 0.00000000000000000000000000004849 121.0
HFD3_k127_6379893_23 DNA-binding transcription factor activity K15973 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000003298 99.0
HFD3_k127_6379893_24 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07658 - - 0.00000000000000000001395 95.0
HFD3_k127_6379893_25 Putative regulatory protein - - - 0.00000000000000000005144 93.0
HFD3_k127_6379893_26 - - - - 0.0000000000000000002932 94.0
HFD3_k127_6379893_27 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.0000000000000001179 88.0
HFD3_k127_6379893_28 Carboxypeptidase regulatory-like domain - - - 0.0000000000000006805 82.0
HFD3_k127_6379893_29 Tetratricopeptide repeats - - - 0.0000000000000007089 91.0
HFD3_k127_6379893_3 PFAM peptidase S58, DmpA K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 445.0
HFD3_k127_6379893_30 membrane - - - 0.000000000000001036 93.0
HFD3_k127_6379893_31 Tetratricopeptide repeat - - - 0.000000000002492 79.0
HFD3_k127_6379893_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008557 441.0
HFD3_k127_6379893_5 symporter activity K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 432.0
HFD3_k127_6379893_6 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 380.0
HFD3_k127_6379893_7 SpoIVB peptidase S55 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005533 390.0
HFD3_k127_6379893_8 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 349.0
HFD3_k127_6379893_9 TIGRFAM LPPG domain K11212 - 2.7.8.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005359 318.0
HFD3_k127_639362_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 577.0
HFD3_k127_639362_1 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004959 525.0
HFD3_k127_639362_2 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009494 370.0
HFD3_k127_639362_3 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000475 185.0
HFD3_k127_639362_4 CDP-archaeol synthase - - - 0.0000000000000000005269 93.0
HFD3_k127_639362_5 MacB-like periplasmic core domain - - - 0.000000000000002137 81.0
HFD3_k127_6397158_0 Sulfatase K01133 - 3.1.6.6 0.000000000000000000000000000000000000000000000000006692 205.0
HFD3_k127_6397158_1 DolP-mannose mannosyltransferase - GO:0000030,GO:0003674,GO:0003824,GO:0004169,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006486,GO:0006493,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019538,GO:0034645,GO:0035268,GO:0035269,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044464,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.0000000001072 74.0
HFD3_k127_6434961_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 4.281e-309 963.0
HFD3_k127_6434961_1 PFAM acetyl-CoA hydrolase transferase K01067 - 3.1.2.1 4.296e-206 647.0
HFD3_k127_6434961_10 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 321.0
HFD3_k127_6434961_11 Peptidase C26 K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001885 274.0
HFD3_k127_6434961_12 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000009536 262.0
HFD3_k127_6434961_13 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000276 235.0
HFD3_k127_6434961_14 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000001488 233.0
HFD3_k127_6434961_15 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000002039 207.0
HFD3_k127_6434961_16 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000005706 192.0
HFD3_k127_6434961_17 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000008948 177.0
HFD3_k127_6434961_18 - - - - 0.00000000000000000000000000000000000000006517 156.0
HFD3_k127_6434961_19 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.000000000000000000000000000000000001133 148.0
HFD3_k127_6434961_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175,K00177,K00187 - 1.2.7.11,1.2.7.3,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 596.0
HFD3_k127_6434961_20 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.00000000000000000000000000006312 119.0
HFD3_k127_6434961_21 chlorophyll binding - - - 0.000000000000000000000002749 111.0
HFD3_k127_6434961_22 Chorismate mutase type II K04093 - 5.4.99.5 0.00000000000000000008651 94.0
HFD3_k127_6434961_23 - - - - 0.000000000000002815 79.0
HFD3_k127_6434961_24 - - - - 0.0000000194 59.0
HFD3_k127_6434961_25 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00008807 55.0
HFD3_k127_6434961_3 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 574.0
HFD3_k127_6434961_4 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 507.0
HFD3_k127_6434961_5 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 491.0
HFD3_k127_6434961_6 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 468.0
HFD3_k127_6434961_7 Pyruvate:ferredoxin oxidoreductase core domain II K00186 - 1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005066 466.0
HFD3_k127_6434961_8 ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009091 373.0
HFD3_k127_6434961_9 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 368.0
HFD3_k127_6471115_0 efflux transmembrane transporter activity K02004 - - 1.212e-234 754.0
HFD3_k127_6471115_1 efflux transmembrane transporter activity K02004 - - 6.53e-222 714.0
HFD3_k127_6471115_10 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000008943 247.0
HFD3_k127_6471115_11 - - - - 0.0000000000000000000000000006536 131.0
HFD3_k127_6471115_12 WD40-like Beta Propeller Repeat - - - 0.00000000006513 66.0
HFD3_k127_6471115_13 PASTA K12132 - 2.7.11.1 0.000000001133 64.0
HFD3_k127_6471115_2 efflux transmembrane transporter activity - - - 1.915e-197 642.0
HFD3_k127_6471115_3 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 597.0
HFD3_k127_6471115_4 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 591.0
HFD3_k127_6471115_5 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008403 557.0
HFD3_k127_6471115_6 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 543.0
HFD3_k127_6471115_7 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008869 535.0
HFD3_k127_6471115_8 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 489.0
HFD3_k127_6471115_9 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 355.0
HFD3_k127_6471765_0 D-aminoacylase domain protein K01465,K06015 - 3.5.1.81,3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004277 612.0
HFD3_k127_6471765_1 N-4 methylation of cytosine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 436.0
HFD3_k127_6471765_2 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000001673 219.0
HFD3_k127_6646606_0 Peptidase dimerisation domain - - - 5.83e-217 684.0
HFD3_k127_6646606_1 Protein of unknown function (DUF763) K09003 - - 7.225e-194 611.0
HFD3_k127_6646606_2 beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 514.0
HFD3_k127_6646606_3 Protein of unknown function (DUF2891) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 458.0
HFD3_k127_6646606_4 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 365.0
HFD3_k127_6646606_5 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000003227 223.0
HFD3_k127_6646606_6 SnoaL-like domain K06893 - - 0.000000000000000000000000000000000000000000006733 167.0
HFD3_k127_6646606_7 Forkhead associated domain - - - 0.0000000000000005389 90.0
HFD3_k127_6646606_8 response to abiotic stimulus K03086,K06867 - - 0.000000000001497 76.0
HFD3_k127_6646606_9 Zinc finger domain - - - 0.00002297 56.0
HFD3_k127_6672333_0 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 561.0
HFD3_k127_6672333_1 NADH dehydrogenase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006552 421.0
HFD3_k127_6672333_2 - - - - 0.000000000000000000000000000000000000000000000000000000000008272 225.0
HFD3_k127_6672333_3 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000008412 179.0
HFD3_k127_6672333_4 serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000134 163.0
HFD3_k127_6672333_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000007636 90.0
HFD3_k127_6765359_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1090.0
HFD3_k127_6765359_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 2.874e-315 989.0
HFD3_k127_6765359_10 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 385.0
HFD3_k127_6765359_11 RNA polymerase sigma-54 factor K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 377.0
HFD3_k127_6765359_12 ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 316.0
HFD3_k127_6765359_13 histidine kinase, HAMP K07642 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004252 302.0
HFD3_k127_6765359_14 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000964 285.0
HFD3_k127_6765359_15 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000001431 224.0
HFD3_k127_6765359_16 COGs COG1432 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000268 217.0
HFD3_k127_6765359_17 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000001609 196.0
HFD3_k127_6765359_18 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000001872 181.0
HFD3_k127_6765359_19 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000303 189.0
HFD3_k127_6765359_2 Prolyl oligopeptidase family - - - 7.56e-232 736.0
HFD3_k127_6765359_20 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000007244 158.0
HFD3_k127_6765359_21 Protein involved in hydrolase activity K06889 - - 0.000000000000000000000000000000000007865 151.0
HFD3_k127_6765359_22 PTS system fructose IIA component K02793,K02794,K02821 - 2.7.1.191,2.7.1.194 0.000000000000000000000000000000000008741 141.0
HFD3_k127_6765359_23 Tetratricopeptide repeat - - - 0.0000000000000000000000000000003145 141.0
HFD3_k127_6765359_24 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K09774 - - 0.000000000000000000000000000005167 139.0
HFD3_k127_6765359_25 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K16079 - - 0.0000000000000000000000000009231 120.0
HFD3_k127_6765359_26 regulation of translation K05808,K05809 GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006417,GO:0006446,GO:0006448,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0045947,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.0000000000000000000000008377 110.0
HFD3_k127_6765359_27 electron transfer activity - - - 0.0000000000000003649 86.0
HFD3_k127_6765359_28 cytochrome C peroxidase - - - 0.0003727 51.0
HFD3_k127_6765359_3 WD40 domain protein beta Propeller K12132 - 2.7.11.1 6.529e-222 718.0
HFD3_k127_6765359_4 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 581.0
HFD3_k127_6765359_5 Carboxylesterase family K03929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 507.0
HFD3_k127_6765359_6 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008639 481.0
HFD3_k127_6765359_7 Protein of unknown function (DUF3089) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 447.0
HFD3_k127_6765359_8 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004948 436.0
HFD3_k127_6765359_9 Belongs to the ABC transporter superfamily K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 385.0
HFD3_k127_6788149_0 peptidase S9B dipeptidylpeptidase IV domain protein K01278 - 3.4.14.5 0.0 1023.0
HFD3_k127_6788149_1 serine-type peptidase activity K01278 - 3.4.14.5 4.4e-323 1002.0
HFD3_k127_6788149_10 Carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006855 376.0
HFD3_k127_6788149_11 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0016783,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 352.0
HFD3_k127_6788149_12 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000004894 266.0
HFD3_k127_6788149_13 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000002741 214.0
HFD3_k127_6788149_14 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000004776 185.0
HFD3_k127_6788149_16 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000001932 113.0
HFD3_k127_6788149_17 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000000000001003 80.0
HFD3_k127_6788149_18 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.00000000002354 65.0
HFD3_k127_6788149_19 TIGRFAM amino acid peptide transporter (Peptide H symporter), bacterial K03305 - - 0.000000000661 61.0
HFD3_k127_6788149_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 3.034e-297 927.0
HFD3_k127_6788149_20 chlorophyll binding - - - 0.0001996 55.0
HFD3_k127_6788149_3 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 7.479e-288 905.0
HFD3_k127_6788149_4 outer membrane efflux protein - - - 5.611e-198 629.0
HFD3_k127_6788149_5 Transport permease protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 559.0
HFD3_k127_6788149_6 beta-N-acetylhexosaminidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 553.0
HFD3_k127_6788149_7 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 528.0
HFD3_k127_6788149_8 PFAM secretion protein HlyD family protein K01993,K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 510.0
HFD3_k127_6788149_9 Belongs to the pyruvate kinase family K00873 GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 412.0
HFD3_k127_6820155_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 574.0
HFD3_k127_6820155_1 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 426.0
HFD3_k127_6820155_2 protein-glutamate O-methyltransferase activity K00575,K03408,K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 400.0
HFD3_k127_6820155_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000008377 73.0
HFD3_k127_6820155_4 PFAM Tetratricopeptide repeat - - - 0.0000001156 63.0
HFD3_k127_6820155_5 peptidyl-tyrosine sulfation - - - 0.00002533 56.0
HFD3_k127_6880646_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 2.362e-273 867.0
HFD3_k127_6880646_1 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 432.0
HFD3_k127_6880646_2 ATP dependent DNA ligase C terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001151 248.0
HFD3_k127_6880646_4 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) K08680 - 4.2.99.20 0.00000000000000002584 87.0
HFD3_k127_6880646_5 Putative transposase of IS4/5 family (DUF4096) - - - 0.0000000000008661 71.0
HFD3_k127_6880646_6 COG2931 RTX toxins and related Ca2 -binding - - - 0.0000000003705 66.0
HFD3_k127_6925138_0 PFAM Amidase - - - 4.059e-271 845.0
HFD3_k127_6925138_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 619.0
HFD3_k127_6925138_10 ChrR Cupin-like domain - - - 0.000001791 50.0
HFD3_k127_6925138_11 protein kinase activity - - - 0.0009052 47.0
HFD3_k127_6925138_2 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008297 604.0
HFD3_k127_6925138_3 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 568.0
HFD3_k127_6925138_4 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 465.0
HFD3_k127_6925138_5 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 313.0
HFD3_k127_6925138_6 RNA polymerase sigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001155 255.0
HFD3_k127_6925138_7 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000001258 145.0
HFD3_k127_6925138_8 - - - - 0.00000000000000000000000427 106.0
HFD3_k127_6925138_9 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000008112 78.0
HFD3_k127_7002504_0 serine-type peptidase activity - - - 0.0 1118.0
HFD3_k127_7002504_1 MacB-like periplasmic core domain - - - 5.242e-237 762.0
HFD3_k127_7002504_10 - - - - 0.0000000000000000000000000000000000001936 145.0
HFD3_k127_7002504_11 DNA glycosylase AP lyase, H2TH DNA-binding K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000604 105.0
HFD3_k127_7002504_12 Thioredoxin domain - - - 0.000000000000000001221 87.0
HFD3_k127_7002504_13 - - - - 0.0000000000000001118 91.0
HFD3_k127_7002504_14 - - - - 0.00000000000003338 76.0
HFD3_k127_7002504_15 - - - - 0.0000000000009285 72.0
HFD3_k127_7002504_16 Glycosyl hydrolase family 26 - - - 0.0000002191 60.0
HFD3_k127_7002504_17 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00002461 49.0
HFD3_k127_7002504_2 Acyl-coa dehydrogenase K00249 - 1.3.8.7 1.094e-199 628.0
HFD3_k127_7002504_3 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004508 508.0
HFD3_k127_7002504_4 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 323.0
HFD3_k127_7002504_5 Beta-lactamase K01256,K17836 - 3.4.11.2,3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 313.0
HFD3_k127_7002504_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004134 317.0
HFD3_k127_7002504_7 O-methyltransferase K00588 - 2.1.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000635 284.0
HFD3_k127_7002504_8 Thioredoxin domain - - - 0.00000000000000000000000000000000000000008246 156.0
HFD3_k127_7002504_9 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000004461 149.0
HFD3_k127_7016600_0 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007331 478.0
HFD3_k127_7016600_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 378.0
HFD3_k127_7016600_10 Signal transduction histidine kinase, nitrogen specific, NtrB K07708,K10942 - 2.7.13.3 0.00000000000000000000000000000000000000000000002147 191.0
HFD3_k127_7016600_11 Urate oxidase N-terminal - - - 0.00000000000000000000000000000000000000000002084 171.0
HFD3_k127_7016600_12 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000007174 140.0
HFD3_k127_7016600_13 Iron-sulphur cluster biosynthesis - - - 0.0000000000000000000000000000000006979 133.0
HFD3_k127_7016600_14 peroxiredoxin activity K03564 - 1.11.1.15 0.0000000000000000000344 93.0
HFD3_k127_7016600_15 multi-organism process - - - 0.0000000000000001592 94.0
HFD3_k127_7016600_16 - - - - 0.000000000000001244 80.0
HFD3_k127_7016600_17 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000611 46.0
HFD3_k127_7016600_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 360.0
HFD3_k127_7016600_3 Cobyrinic acid ac-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006577 294.0
HFD3_k127_7016600_4 integrase domain protein SAM domain protein K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 296.0
HFD3_k127_7016600_5 MOFRL family K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008856 283.0
HFD3_k127_7016600_6 chromosome segregation K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000002901 241.0
HFD3_k127_7016600_7 Histidine kinase K02668,K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000007992 224.0
HFD3_k127_7016600_8 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000001153 203.0
HFD3_k127_7016600_9 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000000000001869 189.0
HFD3_k127_7023878_0 Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 0.0 1258.0
HFD3_k127_7023878_1 Sulfate permease family - - - 4.122e-240 757.0
HFD3_k127_7023878_10 Belongs to the glycosyl hydrolase 13 family - - - 0.00000002807 57.0
HFD3_k127_7023878_11 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000004785 48.0
HFD3_k127_7023878_2 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 451.0
HFD3_k127_7023878_3 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009775 458.0
HFD3_k127_7023878_4 Predicted membrane protein (DUF2254) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 326.0
HFD3_k127_7023878_6 Biotin-lipoyl like K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 296.0
HFD3_k127_7023878_7 CHAD - - - 0.0000000000000000000000000000000000000000007798 169.0
HFD3_k127_7023878_8 Ion transport 2 domain protein - - - 0.00000000000000000000000000005172 124.0
HFD3_k127_7023878_9 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000003512 70.0
HFD3_k127_7042366_0 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 537.0
HFD3_k127_7042366_1 Replicative DNA helicase K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 488.0
HFD3_k127_7042366_10 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000001037 187.0
HFD3_k127_7042366_11 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000879 178.0
HFD3_k127_7042366_12 binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000002878 149.0
HFD3_k127_7042366_13 Cysteine-rich secretory protein family - - - 0.0000000000000000000000000000002557 130.0
HFD3_k127_7042366_14 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000001747 112.0
HFD3_k127_7042366_15 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000002177 108.0
HFD3_k127_7042366_16 Cell wall-active antibiotics response 4TMS YvqF K11622 - - 0.000000006148 63.0
HFD3_k127_7042366_18 general secretion pathway protein G K02456 - - 0.0003445 50.0
HFD3_k127_7042366_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005997 398.0
HFD3_k127_7042366_3 Metal binding domain of Ada K00567,K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 398.0
HFD3_k127_7042366_4 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 385.0
HFD3_k127_7042366_5 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005302 338.0
HFD3_k127_7042366_6 ATPases associated with a variety of cellular activities K05847 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 322.0
HFD3_k127_7042366_7 Histidine-specific methyltransferase, SAM-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001017 282.0
HFD3_k127_7042366_8 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000001743 237.0
HFD3_k127_7042366_9 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000000000000000003816 210.0
HFD3_k127_7044766_0 Tricorn protease C1 domain K08676 - - 0.0 1370.0
HFD3_k127_7044766_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1284.0
HFD3_k127_7044766_10 PFAM Acetamidase Formamidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 455.0
HFD3_k127_7044766_11 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 385.0
HFD3_k127_7044766_12 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 355.0
HFD3_k127_7044766_13 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 336.0
HFD3_k127_7044766_14 Protein of unknown function (DUF512) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004947 348.0
HFD3_k127_7044766_15 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 332.0
HFD3_k127_7044766_16 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 337.0
HFD3_k127_7044766_17 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 327.0
HFD3_k127_7044766_18 Serine aminopeptidase, S33 K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 308.0
HFD3_k127_7044766_19 Methyltransferase domain K00598 - 2.1.1.144 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 302.0
HFD3_k127_7044766_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.994e-310 970.0
HFD3_k127_7044766_20 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009252 297.0
HFD3_k127_7044766_21 Inositol monophosphatase K01082,K01092 GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 295.0
HFD3_k127_7044766_22 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004179 294.0
HFD3_k127_7044766_23 site-specific DNA-methyltransferase (adenine-specific) activity K03427 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000001319 261.0
HFD3_k127_7044766_24 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000007058 224.0
HFD3_k127_7044766_25 MoaE protein K21142 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000000004342 218.0
HFD3_k127_7044766_26 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000002346 211.0
HFD3_k127_7044766_27 translation release factor activity - - - 0.0000000000000000000000000000000000000000000000000000000006612 218.0
HFD3_k127_7044766_28 zinc ion binding - - - 0.00000000000000000000000000000000000000000000000001629 203.0
HFD3_k127_7044766_29 OsmC-like protein K04063 - - 0.000000000000000000000000000000000000000000000001513 178.0
HFD3_k127_7044766_3 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.853e-272 860.0
HFD3_k127_7044766_30 DoxX - - - 0.0000000000000000000000000000000000000000000002266 173.0
HFD3_k127_7044766_31 EthD domain - - - 0.0000000000000000000000000000000000002151 143.0
HFD3_k127_7044766_32 Protein of unknown function (DUF3303) - - - 0.00000000000000000000000000008655 119.0
HFD3_k127_7044766_33 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000001065 124.0
HFD3_k127_7044766_34 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000001314 116.0
HFD3_k127_7044766_35 SMART Mov34 MPN PAD-1 family protein - - - 0.00000000000000000000000003726 112.0
HFD3_k127_7044766_36 HEAT repeat - - - 0.0000000000000000000000002592 118.0
HFD3_k127_7044766_37 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 0.000000000000000000000003003 111.0
HFD3_k127_7044766_38 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000001197 102.0
HFD3_k127_7044766_39 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000000000004701 70.0
HFD3_k127_7044766_4 Amidohydrolase family - - - 1.731e-250 782.0
HFD3_k127_7044766_40 COG0084 Mg-dependent DNase K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.00000000002664 64.0
HFD3_k127_7044766_41 Polysaccharide biosynthesis/export protein K01991 - - 0.0000000007386 68.0
HFD3_k127_7044766_42 Outer membrane lipoprotein - - - 0.000000001724 68.0
HFD3_k127_7044766_43 CBS domain - - - 0.00000003376 61.0
HFD3_k127_7044766_44 - - - - 0.0000002168 62.0
HFD3_k127_7044766_5 PFAM Amidase - - - 3.195e-199 636.0
HFD3_k127_7044766_6 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 530.0
HFD3_k127_7044766_7 Aldo Keto reductase K05882 - 1.1.1.91 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 492.0
HFD3_k127_7044766_8 Metalloenzyme superfamily K01839 - 5.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 469.0
HFD3_k127_7044766_9 AMP-binding enzyme C-terminal domain K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 468.0
HFD3_k127_7085200_0 Zinc-binding dehydrogenase - - - 2.217e-213 689.0
HFD3_k127_7085200_1 Highly conserved protein containing a thioredoxin domain K20948 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 325.0
HFD3_k127_7085200_10 metallopeptidase activity - - - 0.00000000000000000000000000001502 127.0
HFD3_k127_7085200_11 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000001232 113.0
HFD3_k127_7085200_12 Disulphide bond corrector protein DsbC - - - 0.000000000000000000006852 99.0
HFD3_k127_7085200_13 AAA ATPase domain - - - 0.0000000000000000003533 103.0
HFD3_k127_7085200_14 Recombinase zinc beta ribbon domain K06400 - - 0.0000006466 52.0
HFD3_k127_7085200_2 Molybdenum cofactor synthesis domain protein K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 317.0
HFD3_k127_7085200_3 PFAM sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 317.0
HFD3_k127_7085200_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003034 305.0
HFD3_k127_7085200_5 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003473 273.0
HFD3_k127_7085200_6 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000002046 249.0
HFD3_k127_7085200_7 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) - - - 0.0000000000000000000000000000000000000000000000004236 180.0
HFD3_k127_7085200_8 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000003448 177.0
HFD3_k127_7085200_9 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000005969 166.0
HFD3_k127_7094374_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1134.0
HFD3_k127_7094374_1 Carbon starvation protein K06200 - - 2.169e-213 678.0
HFD3_k127_7094374_10 Enoyl-CoA hydratase K07539,K18570 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000004302 276.0
HFD3_k127_7094374_11 IstB-like ATP binding protein K02315 - - 0.000000000000000000000000000000000000000000000000000000000000000000005289 242.0
HFD3_k127_7094374_12 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K03585 - - 0.0000000000000000000000000000000000000000000000000000000003399 218.0
HFD3_k127_7094374_13 PFAM glycosyl transferase family 39 - - - 0.000000000000000000000000000000000000000000000000000001152 212.0
HFD3_k127_7094374_14 four-way junction helicase activity K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.000000000000000000000000000000000000000000000001552 180.0
HFD3_k127_7094374_15 Dehydrogenase E1 component K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000003931 188.0
HFD3_k127_7094374_16 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000004412 168.0
HFD3_k127_7094374_17 - - - - 0.000000000000000000000000000000000007052 150.0
HFD3_k127_7094374_18 - - - - 0.000000000000000000000000634 108.0
HFD3_k127_7094374_19 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000001563 106.0
HFD3_k127_7094374_2 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 506.0
HFD3_k127_7094374_20 hyperosmotic response K04065 - - 0.000000000000000001643 95.0
HFD3_k127_7094374_21 Ankyrin 1, erythrocytic K10380,K15502,K15503 - - 0.000000000000001526 83.0
HFD3_k127_7094374_23 Prokaryotic N-terminal methylation motif K02650 - - 0.0002259 52.0
HFD3_k127_7094374_3 overlaps another CDS with the same product name - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 444.0
HFD3_k127_7094374_4 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005084 364.0
HFD3_k127_7094374_5 Voltage gated chloride channel K03281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 343.0
HFD3_k127_7094374_6 AcrB/AcrD/AcrF family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 327.0
HFD3_k127_7094374_7 Oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 304.0
HFD3_k127_7094374_8 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 286.0
HFD3_k127_7094374_9 protease with the C-terminal PDZ domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007968 303.0
HFD3_k127_7158867_0 serine-type peptidase activity K01278 - 3.4.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 512.0
HFD3_k127_7158867_1 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005692 357.0
HFD3_k127_7158867_2 DolP-mannose mannosyltransferase - GO:0000030,GO:0003674,GO:0003824,GO:0004169,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006486,GO:0006493,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019538,GO:0034645,GO:0035268,GO:0035269,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044464,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.000001269 61.0
HFD3_k127_7158867_3 DolP-mannose mannosyltransferase - GO:0000030,GO:0003674,GO:0003824,GO:0004169,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006486,GO:0006493,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019538,GO:0034645,GO:0035268,GO:0035269,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044464,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.000001715 61.0
HFD3_k127_7181465_0 helicase activity - - - 0.0 1033.0
HFD3_k127_7181465_1 Dienelactone hydrolase family - - - 3.612e-240 763.0
HFD3_k127_7181465_10 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008717 311.0
HFD3_k127_7181465_11 surface antigen variable number - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 314.0
HFD3_k127_7181465_12 Binding-protein-dependent transport system inner membrane component K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006312 286.0
HFD3_k127_7181465_13 Hexapeptide repeat of succinyl-transferase K13018 - 2.3.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001964 276.0
HFD3_k127_7181465_14 Sterol-sensing domain of SREBP cleavage-activation K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000042 250.0
HFD3_k127_7181465_15 Lumazine binding domain K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000003936 218.0
HFD3_k127_7181465_16 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000001366 210.0
HFD3_k127_7181465_17 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000004647 219.0
HFD3_k127_7181465_18 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000000000000000006765 202.0
HFD3_k127_7181465_19 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000011 200.0
HFD3_k127_7181465_2 Glutamine amidotransferases class-II K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006394 595.0
HFD3_k127_7181465_20 protein secretion K09800 - - 0.0000000000000000000000000000000000000000000000000000001477 224.0
HFD3_k127_7181465_21 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000000000000000000002523 160.0
HFD3_k127_7181465_22 Belongs to the ArsC family K00537 - 1.20.4.1 0.0000000000000000000000000000000000002029 149.0
HFD3_k127_7181465_23 Belongs to the SEDS family K03588 GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136 - 0.000000000000000000000000000000003581 142.0
HFD3_k127_7181465_24 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000001708 127.0
HFD3_k127_7181465_25 Dodecin K09165 - - 0.00000000000000000000016 99.0
HFD3_k127_7181465_26 - - - - 0.000000000000000000003039 98.0
HFD3_k127_7181465_27 Lysin motif - - - 0.00000000000000000008694 95.0
HFD3_k127_7181465_29 Tetratricopeptide repeat - - - 0.000000000000001932 86.0
HFD3_k127_7181465_3 amino acid K20265 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0006873,GO:0006885,GO:0008150,GO:0008509,GO:0008514,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0019725,GO:0022804,GO:0022857,GO:0030003,GO:0030004,GO:0030641,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0045852,GO:0046942,GO:0046943,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0051454,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:0098771,GO:1902475,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004839 492.0
HFD3_k127_7181465_30 integral membrane protein - - - 0.00000000000009227 81.0
HFD3_k127_7181465_31 Outer membrane lipoprotein-sorting protein - - - 0.000000000003754 77.0
HFD3_k127_7181465_32 Beta-lactamase - - - 0.00000000003363 68.0
HFD3_k127_7181465_33 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.0000000001613 71.0
HFD3_k127_7181465_34 von Willebrand factor, type A K07114 - - 0.000000151 63.0
HFD3_k127_7181465_4 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 485.0
HFD3_k127_7181465_5 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008602 417.0
HFD3_k127_7181465_6 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 396.0
HFD3_k127_7181465_7 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 380.0
HFD3_k127_7181465_8 Major intrinsic protein K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006549 365.0
HFD3_k127_7181465_9 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 365.0
HFD3_k127_7183934_0 Protein export membrane protein K03296,K18138 - - 0.0 1242.0
HFD3_k127_7183934_1 Tricorn protease homolog K08676 - - 0.0 1093.0
HFD3_k127_7183934_2 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 4.349e-237 752.0
HFD3_k127_7183934_3 transcription factor binding K02584,K12146,K12266,K15836,K21009 GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141 - 3.049e-211 676.0
HFD3_k127_7183934_4 esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 387.0
HFD3_k127_7183934_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006597 361.0
HFD3_k127_7183934_6 - - - - 0.00000000000000000000000000000000000000000000001513 179.0
HFD3_k127_7183934_7 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000003996 149.0
HFD3_k127_722422_0 xanthine dehydrogenase activity K04108 - 1.3.7.9 4.216e-307 960.0
HFD3_k127_722422_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.286e-275 857.0
HFD3_k127_722422_10 SMART PDZ DHR GLGF domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 362.0
HFD3_k127_722422_11 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 343.0
HFD3_k127_722422_12 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006188 312.0
HFD3_k127_722422_13 signal sequence binding K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 306.0
HFD3_k127_722422_14 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000003273 252.0
HFD3_k127_722422_15 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009433 243.0
HFD3_k127_722422_16 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000001032 236.0
HFD3_k127_722422_17 protein flavinylation K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000004921 240.0
HFD3_k127_722422_18 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000002377 231.0
HFD3_k127_722422_19 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K15546 - - 0.00000000000000000000000000000000000000000000000008611 188.0
HFD3_k127_722422_2 Polysulphide reductase, NrfD K00185 - - 1.257e-224 703.0
HFD3_k127_722422_20 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000003185 180.0
HFD3_k127_722422_21 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000001822 166.0
HFD3_k127_722422_22 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.0000000000000000000000001899 108.0
HFD3_k127_722422_23 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000007421 99.0
HFD3_k127_722422_24 - - - - 0.00000000007473 69.0
HFD3_k127_722422_25 CYTH - - - 0.00000002246 66.0
HFD3_k127_722422_26 Putative restriction endonuclease - - - 0.0000957 46.0
HFD3_k127_722422_3 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 436.0
HFD3_k127_722422_4 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000674 432.0
HFD3_k127_722422_5 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 424.0
HFD3_k127_722422_6 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 397.0
HFD3_k127_722422_7 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 390.0
HFD3_k127_722422_8 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000862 380.0
HFD3_k127_722422_9 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005113 354.0
HFD3_k127_7225083_0 Sortilin, neurotensin receptor 3, - - - 0.0 1478.0
HFD3_k127_7225083_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1134.0
HFD3_k127_7225083_10 threonine synthase activity K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 522.0
HFD3_k127_7225083_11 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 516.0
HFD3_k127_7225083_12 Belongs to the PEP-utilizing enzyme family K01006,K01007 - 2.7.9.1,2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 520.0
HFD3_k127_7225083_13 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007536 505.0
HFD3_k127_7225083_14 Zn-dependent dipeptidase, microsomal dipeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006043 495.0
HFD3_k127_7225083_15 Zinc dependent phospholipase C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 496.0
HFD3_k127_7225083_16 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004679 485.0
HFD3_k127_7225083_17 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00366 - 1.7.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004325 483.0
HFD3_k127_7225083_18 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 467.0
HFD3_k127_7225083_19 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007343 483.0
HFD3_k127_7225083_2 Dienelactone hydrolase family - - - 3.67e-293 913.0
HFD3_k127_7225083_20 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 472.0
HFD3_k127_7225083_21 C-terminal, D2-small domain, of ClpB protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000838 451.0
HFD3_k127_7225083_22 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 435.0
HFD3_k127_7225083_23 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 400.0
HFD3_k127_7225083_24 NAD NADP transhydrogenase alpha subunit K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 394.0
HFD3_k127_7225083_25 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 391.0
HFD3_k127_7225083_26 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008775 339.0
HFD3_k127_7225083_27 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004431 337.0
HFD3_k127_7225083_28 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 344.0
HFD3_k127_7225083_29 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008242 346.0
HFD3_k127_7225083_3 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 2.376e-279 869.0
HFD3_k127_7225083_30 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 333.0
HFD3_k127_7225083_31 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000526 331.0
HFD3_k127_7225083_32 esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 325.0
HFD3_k127_7225083_33 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009058 325.0
HFD3_k127_7225083_34 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003985 288.0
HFD3_k127_7225083_35 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001107 287.0
HFD3_k127_7225083_36 converts alpha-aldose to the beta-anomer - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001855 276.0
HFD3_k127_7225083_37 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000005063 266.0
HFD3_k127_7225083_38 Belongs to the PAPS reductase family. CysH subfamily K00390,K00860 GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114 1.8.4.10,1.8.4.8,2.7.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000006652 266.0
HFD3_k127_7225083_39 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000144 266.0
HFD3_k127_7225083_4 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 1.243e-214 674.0
HFD3_k127_7225083_40 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000001023 267.0
HFD3_k127_7225083_41 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006325 259.0
HFD3_k127_7225083_42 amine dehydrogenase activity K14647,K21449 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006245 269.0
HFD3_k127_7225083_43 TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000001223 249.0
HFD3_k127_7225083_44 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000001893 255.0
HFD3_k127_7225083_45 Histidine biosynthesis bifunctional protein HisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000001939 246.0
HFD3_k127_7225083_46 PFAM Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000001102 238.0
HFD3_k127_7225083_47 COGs COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000002022 238.0
HFD3_k127_7225083_48 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003662 257.0
HFD3_k127_7225083_49 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000003139 237.0
HFD3_k127_7225083_5 glutamine synthetase K01915 - 6.3.1.2 8.055e-205 646.0
HFD3_k127_7225083_50 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000007647 234.0
HFD3_k127_7225083_51 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000007366 230.0
HFD3_k127_7225083_52 acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000008695 243.0
HFD3_k127_7225083_53 Belongs to the Dps family K04047 - - 0.0000000000000000000000000000000000000000000000000000000000000002585 229.0
HFD3_k127_7225083_54 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000000000000003641 215.0
HFD3_k127_7225083_55 Catalyzes the synthesis of activated sulfate K00860 - 2.7.1.25 0.0000000000000000000000000000000000000000000000000000000000004357 216.0
HFD3_k127_7225083_56 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000003296 203.0
HFD3_k127_7225083_57 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000003671 208.0
HFD3_k127_7225083_58 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000008495 207.0
HFD3_k127_7225083_59 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000000000000000000001613 219.0
HFD3_k127_7225083_6 Tetratricopeptide repeats K12132 - 2.7.11.1 8.525e-196 635.0
HFD3_k127_7225083_60 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000000000000000000000000000000000000000000000000000001954 209.0
HFD3_k127_7225083_61 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000001708 185.0
HFD3_k127_7225083_62 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000000000000000000000000000000002745 178.0
HFD3_k127_7225083_63 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000000006236 169.0
HFD3_k127_7225083_65 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000008635 166.0
HFD3_k127_7225083_66 Ribosomal protein L19 K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000008639 158.0
HFD3_k127_7225083_67 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000002574 154.0
HFD3_k127_7225083_68 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.000000000000000000000000000000000000006278 147.0
HFD3_k127_7225083_69 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.00000000000000000000000000000000000003666 152.0
HFD3_k127_7225083_7 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 615.0
HFD3_k127_7225083_70 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000001372 157.0
HFD3_k127_7225083_71 PFAM TfoX N-terminal domain K07343 - - 0.0000000000000000000000000000003572 130.0
HFD3_k127_7225083_72 MOSC domain - - - 0.000000000000000000000000000002142 122.0
HFD3_k127_7225083_73 Belongs to the ClpA ClpB family K03696 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - 0.000000000000000000000000000005831 133.0
HFD3_k127_7225083_74 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000000000000000003768 123.0
HFD3_k127_7225083_75 palmitoyl-(protein) hydrolase activity K06999 - - 0.0000000000000000000000000006137 122.0
HFD3_k127_7225083_76 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.0000000000000000000000000309 114.0
HFD3_k127_7225083_77 PFAM Pentapeptide repeats (8 copies) - - - 0.0000000000000000000000004277 120.0
HFD3_k127_7225083_78 Ribosomal protein S16 K02959 - - 0.000000000000000000000003131 105.0
HFD3_k127_7225083_79 - - - - 0.000000000000000000000004696 108.0
HFD3_k127_7225083_8 glutamate synthase (NADPH) K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007455 592.0
HFD3_k127_7225083_80 Molybdopterin converting factor, small subunit K03636 - - 0.00000000000000000000002042 104.0
HFD3_k127_7225083_81 SNARE associated Golgi protein - - - 0.00000000000000000000002182 108.0
HFD3_k127_7225083_82 Belongs to the UPF0109 family K06960 - - 0.0000000000000000000002879 98.0
HFD3_k127_7225083_83 PIN domain - - - 0.0000000000000000000008259 100.0
HFD3_k127_7225083_84 PFAM SNARE associated Golgi protein - - - 0.0000000000000000007247 95.0
HFD3_k127_7225083_85 cheY-homologous receiver domain K22010 - - 0.000000000000000003151 94.0
HFD3_k127_7225083_86 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000007805 91.0
HFD3_k127_7225083_87 Tetratricopeptide repeat - - - 0.00000000000000001368 86.0
HFD3_k127_7225083_88 energy transducer activity K03832 - - 0.0000000000000001682 89.0
HFD3_k127_7225083_89 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000004039 89.0
HFD3_k127_7225083_9 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 545.0
HFD3_k127_7225083_90 Tetratricopeptide repeat K06665 GO:0000122,GO:0000228,GO:0000785,GO:0000790,GO:0000988,GO:0000989,GO:0001076,GO:0001190,GO:0001191,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0006139,GO:0006323,GO:0006325,GO:0006333,GO:0006338,GO:0006342,GO:0006351,GO:0006355,GO:0006357,GO:0006366,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016043,GO:0016070,GO:0016458,GO:0016584,GO:0017053,GO:0018130,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0022607,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031497,GO:0031974,GO:0031981,GO:0032774,GO:0032879,GO:0032991,GO:0034641,GO:0034645,GO:0034654,GO:0034728,GO:0035950,GO:0035952,GO:0035953,GO:0035955,GO:0040029,GO:0042304,GO:0042826,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044451,GO:0044454,GO:0044464,GO:0045814,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045944,GO:0046483,GO:0046890,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051276,GO:0060255,GO:0062012,GO:0065007,GO:0070013,GO:0071103,GO:0071704,GO:0071824,GO:0071840,GO:0072364,GO:0080090,GO:0080134,GO:0080135,GO:0090087,GO:0090088,GO:0090089,GO:0090304,GO:0090568,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2000531,GO:2000877,GO:2000879,GO:2001020,GO:2001141 - 0.00000000000001717 85.0
HFD3_k127_7225083_91 G5 domain protein - - - 0.00000000000007749 79.0
HFD3_k127_7225083_92 Putative zinc-finger - GO:0005575,GO:0016020 - 0.0000006672 60.0
HFD3_k127_7225083_93 gag-polyprotein putative aspartyl protease - - - 0.0000006818 62.0
HFD3_k127_7225083_94 Tetratricopeptide repeat protein - - - 0.00001352 56.0
HFD3_k127_7225083_95 - - - - 0.00007813 49.0
HFD3_k127_7247087_0 Ankyrin repeats (many copies) - - - 1.822e-209 674.0
HFD3_k127_7247087_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 618.0
HFD3_k127_7247087_10 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000362 375.0
HFD3_k127_7247087_11 PFAM Peptidase M16 inactive domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000745 321.0
HFD3_k127_7247087_12 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 309.0
HFD3_k127_7247087_13 required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 301.0
HFD3_k127_7247087_14 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008058 292.0
HFD3_k127_7247087_15 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009078 296.0
HFD3_k127_7247087_16 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003099 286.0
HFD3_k127_7247087_17 Zinc-binding dehydrogenase K00060 - 1.1.1.103 0.0000000000000000000000000000000000000000000000000000000000000000000000000001751 270.0
HFD3_k127_7247087_18 Peptidase M16 inactive domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002489 239.0
HFD3_k127_7247087_19 recA bacterial DNA recombination protein - - - 0.000000000000000000000000000000000000000000000000000002705 200.0
HFD3_k127_7247087_2 Two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004961 546.0
HFD3_k127_7247087_20 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000007206 183.0
HFD3_k127_7247087_21 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000001566 184.0
HFD3_k127_7247087_22 Belongs to the peptidase S41A family K06399 - 3.4.21.116 0.000000000000000000000000000000000000000000000169 185.0
HFD3_k127_7247087_23 - - - - 0.0000000000000000000000000000000000000000000171 167.0
HFD3_k127_7247087_24 - - - - 0.000000000000000000000000000000000000000004003 161.0
HFD3_k127_7247087_25 Tyrosine phosphatase family - - - 0.00000000000000000000000000000000000000004174 158.0
HFD3_k127_7247087_26 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000002672 147.0
HFD3_k127_7247087_27 Yqey-like protein K09117 - - 0.000000000000000000000000000000000002367 143.0
HFD3_k127_7247087_28 PFAM von Willebrand factor type A - - - 0.000000000000000000000000000000000006878 150.0
HFD3_k127_7247087_29 - - - - 0.000000000000000000000000000000007397 146.0
HFD3_k127_7247087_3 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 515.0
HFD3_k127_7247087_30 - - - - 0.000000000000000000000000001815 121.0
HFD3_k127_7247087_31 Uncharacterized protein conserved in bacteria (DUF2199) - - - 0.0000000000000000000000001747 112.0
HFD3_k127_7247087_32 Tyrosine phosphatase family - - - 0.000000000000000000000004869 109.0
HFD3_k127_7247087_33 Regulatory protein, FmdB family - - - 0.0000000000000000000006028 96.0
HFD3_k127_7247087_34 PFAM membrane-flanked domain - - - 0.00000001406 63.0
HFD3_k127_7247087_4 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 473.0
HFD3_k127_7247087_5 Putative serine dehydratase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 452.0
HFD3_k127_7247087_6 Involved in the heme and chlorophyll biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 395.0
HFD3_k127_7247087_7 PFAM Transposase IS116 IS110 IS902 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 398.0
HFD3_k127_7247087_8 2-amino-3-ketobutyrate coenzyme A ligase K00639,K00652 - 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 392.0
HFD3_k127_7247087_9 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 387.0
HFD3_k127_7291418_0 PFAM Peptidase M20 - - - 0.000000000000000000000000000000000000000000000000000000000000001817 233.0
HFD3_k127_7291418_1 von Willebrand factor, type A - - - 0.0000000000000000000000006042 118.0
HFD3_k127_7291418_2 deoxyhypusine monooxygenase activity - - - 0.000003519 59.0
HFD3_k127_7313727_0 HELICc2 K03722 - 3.6.4.12 2.063e-194 627.0
HFD3_k127_7313727_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 609.0
HFD3_k127_7313727_10 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008175 401.0
HFD3_k127_7313727_11 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 389.0
HFD3_k127_7313727_12 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 319.0
HFD3_k127_7313727_13 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 286.0
HFD3_k127_7313727_14 NAD dependent epimerase/dehydratase family K07535 - - 0.000000000000000000000000000000000000000000000000000000000000000000001277 244.0
HFD3_k127_7313727_15 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000472 252.0
HFD3_k127_7313727_16 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002058 242.0
HFD3_k127_7313727_17 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.0000000000000000000000000000000000000000000000000000000000000006771 234.0
HFD3_k127_7313727_18 PFAM microcompartments protein K04027 - - 0.00000000000000000000000000000000003083 139.0
HFD3_k127_7313727_19 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K00797,K01611 - 2.5.1.16,4.1.1.50 0.00000000000000000000000000000008562 130.0
HFD3_k127_7313727_2 glycine hydroxymethyltransferase activity K00600 GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006546,GO:0006563,GO:0006565,GO:0006730,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009070,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019264,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042133,GO:0042135,GO:0042136,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000541 570.0
HFD3_k127_7313727_20 hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000009144 122.0
HFD3_k127_7313727_23 Domain of Unknown Function (DUF350) - - - 0.000000000000000002329 89.0
HFD3_k127_7313727_24 Alpha/beta hydrolase family - - - 0.000000000000000006998 94.0
HFD3_k127_7313727_26 Helix-turn-helix domain - - - 0.00000000000005385 83.0
HFD3_k127_7313727_27 - - - - 0.0000000000004897 76.0
HFD3_k127_7313727_28 - - - - 0.000001563 53.0
HFD3_k127_7313727_3 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 542.0
HFD3_k127_7313727_4 Domain of unknown function (DUF4070) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 520.0
HFD3_k127_7313727_5 Domain of unknown function (DUF4178) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005525 501.0
HFD3_k127_7313727_6 Peptidase, M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 493.0
HFD3_k127_7313727_7 Aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 491.0
HFD3_k127_7313727_8 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 454.0
HFD3_k127_7313727_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 432.0
HFD3_k127_7341220_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006 648.0
HFD3_k127_7341220_1 methylisocitrate lyase activity K03417 - 4.1.3.30 0.00000000000000000000000000000000000000000000000000005391 194.0
HFD3_k127_7341220_2 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.000001371 51.0
HFD3_k127_752463_0 cytochrome c peroxidase K00428 - 1.11.1.5 2.748e-236 755.0
HFD3_k127_752463_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 552.0
HFD3_k127_752463_10 Major intrinsic protein K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000005859 232.0
HFD3_k127_752463_11 Protein of unknown function (DUF969) - - - 0.0000000000000000000000000000000000000000000000000001693 194.0
HFD3_k127_752463_13 hyperosmotic response - - - 0.000000001365 68.0
HFD3_k127_752463_2 phosphoesterase, PA-phosphatase related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007199 500.0
HFD3_k127_752463_3 D-arabinono-1,4-lactone oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 463.0
HFD3_k127_752463_4 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009248 449.0
HFD3_k127_752463_5 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 454.0
HFD3_k127_752463_6 Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 300.0
HFD3_k127_752463_7 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 295.0
HFD3_k127_752463_8 helix_turn_helix gluconate operon transcriptional repressor K07978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000114 287.0
HFD3_k127_752463_9 Protein of unknown function (DUF979) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003634 260.0
HFD3_k127_7525511_0 DEAD DEAH box helicase K03724 - - 0.0 1739.0
HFD3_k127_7525511_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1371.0
HFD3_k127_7525511_10 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002974 259.0
HFD3_k127_7525511_11 COG0515 Serine threonine protein K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000003328 254.0
HFD3_k127_7525511_12 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000007284 239.0
HFD3_k127_7525511_13 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000009294 246.0
HFD3_k127_7525511_14 5-formyltetrahydrofolate cycloligase K01934 - 6.3.3.2 0.000000000000000000000000000000000000000000000000000000000000001826 228.0
HFD3_k127_7525511_15 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000002468 227.0
HFD3_k127_7525511_16 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000733 199.0
HFD3_k127_7525511_17 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000009873 204.0
HFD3_k127_7525511_18 EVE domain - - - 0.00000000000000000000000000000000000000000000000000000505 194.0
HFD3_k127_7525511_19 Dna alkylation repair - - - 0.000000000000000000000000000000000000000000000000000114 193.0
HFD3_k127_7525511_2 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.0 1298.0
HFD3_k127_7525511_20 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000004861 190.0
HFD3_k127_7525511_21 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000006592 153.0
HFD3_k127_7525511_23 DsrE/DsrF-like family K09004 - - 0.0000000000000000000000000000000000926 143.0
HFD3_k127_7525511_24 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000001879 113.0
HFD3_k127_7525511_25 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000001521 108.0
HFD3_k127_7525511_26 - - - - 0.0000000000000000000023 102.0
HFD3_k127_7525511_27 Protein of unknown function (DUF2892) - - - 0.000000000000000000003779 95.0
HFD3_k127_7525511_3 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 4.018e-205 658.0
HFD3_k127_7525511_4 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 467.0
HFD3_k127_7525511_5 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 348.0
HFD3_k127_7525511_6 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K14161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005054 351.0
HFD3_k127_7525511_7 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 338.0
HFD3_k127_7525511_8 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 323.0
HFD3_k127_7525511_9 PFAM Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000947 272.0
HFD3_k127_768756_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 5.824e-315 995.0
HFD3_k127_768756_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008861 576.0
HFD3_k127_768756_10 threonine synthase activity K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 420.0
HFD3_k127_768756_11 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 376.0
HFD3_k127_768756_12 In Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007065 364.0
HFD3_k127_768756_13 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 307.0
HFD3_k127_768756_14 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001917 276.0
HFD3_k127_768756_15 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000496 269.0
HFD3_k127_768756_16 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000001881 233.0
HFD3_k127_768756_17 Uncharacterised protein family UPF0066 - - - 0.00000000000000000000000000000000000000000000000000000000000006526 216.0
HFD3_k127_768756_18 oxidoreductase activity K12511 - - 0.0000000000000000000000000000000000000000000000000000000000003803 226.0
HFD3_k127_768756_19 lactoylglutathione lyase activity K11210,K21253,K21264,K21265 GO:0003674,GO:0003824,GO:0004364,GO:0008150,GO:0016740,GO:0016765,GO:0042221,GO:0046677,GO:0050896 2.5.1.18 0.000000000000000000000000000000000000000000000000001082 186.0
HFD3_k127_768756_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 544.0
HFD3_k127_768756_20 oxidoreductase activity K12511 - - 0.00000000000000000000000000000000000000000000007699 182.0
HFD3_k127_768756_21 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.00000000000000000000000000000000000000004081 162.0
HFD3_k127_768756_22 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E K07025 - - 0.000000000000000000000000000003187 129.0
HFD3_k127_768756_23 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000001139 122.0
HFD3_k127_768756_24 von Willebrand factor, type A K07114 - - 0.00000000000000000000000005497 119.0
HFD3_k127_768756_25 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000001637 105.0
HFD3_k127_768756_26 Protein of unknown function (DUF983) - - - 0.000000000000000001778 91.0
HFD3_k127_768756_27 CYTH K01768 - 4.6.1.1 0.00000003655 62.0
HFD3_k127_768756_28 general stress protein - - - 0.00000004351 60.0
HFD3_k127_768756_3 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 530.0
HFD3_k127_768756_4 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 514.0
HFD3_k127_768756_5 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 511.0
HFD3_k127_768756_6 Amidohydrolase family K01465,K06015 - 3.5.1.81,3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009649 508.0
HFD3_k127_768756_7 peptidase dimerisation domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004967 470.0
HFD3_k127_768756_8 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 470.0
HFD3_k127_768756_9 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01431 - 3.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006247 435.0
HFD3_k127_79110_0 Protein of unknown function, DUF255 K06888 - - 3.466e-240 760.0
HFD3_k127_79110_1 PFAM Aldehyde dehydrogenase K00294 - 1.2.1.88 3.67e-208 659.0
HFD3_k127_79110_10 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 388.0
HFD3_k127_79110_11 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 396.0
HFD3_k127_79110_12 Acts as a magnesium transporter K03281,K04767,K06213,K15986 GO:0000287,GO:0003674,GO:0005488,GO:0005515,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015693,GO:0030001,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0051179,GO:0051234,GO:0070838,GO:0072511 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 319.0
HFD3_k127_79110_13 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 300.0
HFD3_k127_79110_14 undecaprenyl-diphosphatase activity K06153 GO:0006950,GO:0008150,GO:0050896,GO:0051409 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004684 287.0
HFD3_k127_79110_15 Glutamine cyclotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003557 273.0
HFD3_k127_79110_16 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000009362 230.0
HFD3_k127_79110_17 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000004623 223.0
HFD3_k127_79110_18 tigr00255 - - - 0.0000000000000000000000000000000000000000000000000000000000009916 220.0
HFD3_k127_79110_19 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000000472 220.0
HFD3_k127_79110_2 amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 601.0
HFD3_k127_79110_20 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.0000000000000000000000000000000000000000000000000007798 204.0
HFD3_k127_79110_21 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000004351 185.0
HFD3_k127_79110_22 PDZ DHR GLGF domain protein - - - 0.000000000000000000000000000000000000000000007291 179.0
HFD3_k127_79110_23 YHS domain K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000009494 166.0
HFD3_k127_79110_24 Belongs to the BI1 family K06890,K19416 - - 0.0000000000000000000000000000000000000005552 158.0
HFD3_k127_79110_25 Protein of unknown function (DUF2834) - - - 0.000000000000000000000000000000000000000559 152.0
HFD3_k127_79110_26 PBS lyase HEAT-like repeat - - - 0.00000000000000000000000000000004538 146.0
HFD3_k127_79110_27 Cupin domain - - - 0.000000000000000000000003498 106.0
HFD3_k127_79110_28 transcriptional regulator - - - 0.00000000000000000002444 99.0
HFD3_k127_79110_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 561.0
HFD3_k127_79110_30 Tetratricopeptide repeat - - - 0.000000000000000005156 98.0
HFD3_k127_79110_32 YbbR-like protein - - - 0.00000000000001607 84.0
HFD3_k127_79110_33 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000004535 74.0
HFD3_k127_79110_34 NAD(P)-dependent K07119 - - 0.0000000000002022 72.0
HFD3_k127_79110_35 RDD family - - - 0.0000000001224 74.0
HFD3_k127_79110_36 sequence-specific DNA binding - - - 0.00000002615 62.0
HFD3_k127_79110_37 Belongs to the 'phage' integrase family - - - 0.000001657 51.0
HFD3_k127_79110_38 DNA-directed 5'-3' RNA polymerase activity K03060 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.000003349 51.0
HFD3_k127_79110_39 Peptidoglycan-binding domain 1 protein - - - 0.00002085 55.0
HFD3_k127_79110_4 PFAM LmbE family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007912 537.0
HFD3_k127_79110_40 - - - - 0.0001064 53.0
HFD3_k127_79110_5 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046483,GO:0050896,GO:0051704,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 480.0
HFD3_k127_79110_6 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 461.0
HFD3_k127_79110_7 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 449.0
HFD3_k127_79110_8 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008317 414.0
HFD3_k127_79110_9 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 392.0
HFD3_k127_798829_0 G-rich domain on putative tyrosine kinase K08252,K16554 - 2.7.10.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004097 338.0
HFD3_k127_798829_1 Peptidase family C25 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001139 307.0
HFD3_k127_798829_2 Peptidase family C25 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005152 264.0
HFD3_k127_798829_3 - - - - 0.000000000000000000000000000000000000000000001733 177.0
HFD3_k127_798829_4 Polysaccharide export protein K01991,K20988 - - 0.00000000000000000000000000001674 132.0
HFD3_k127_798829_6 Tetratricopeptide repeat - - - 0.0000000000000107 87.0
HFD3_k127_798829_7 Belongs to the peptidase S8 family - - - 0.00000000000001089 90.0
HFD3_k127_798829_8 Uncharacterised nucleotidyltransferase - - - 0.00000008756 64.0
HFD3_k127_817005_0 lipid kinase, YegS Rv2252 BmrU family - - - 0.00000000000000000000000000000000000000000000000000001982 201.0
HFD3_k127_817005_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 0.00000000000000000000000000000000000000000000002637 171.0
HFD3_k127_817005_2 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000002084 161.0
HFD3_k127_817005_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000003299 153.0
HFD3_k127_817005_4 methyltransferase - - - 0.00000000000000000000000000001848 128.0
HFD3_k127_817743_0 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 589.0
HFD3_k127_817743_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000514 545.0
HFD3_k127_817743_2 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 356.0
HFD3_k127_817743_3 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000004297 240.0
HFD3_k127_817743_4 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000000000000000000000001406 218.0
HFD3_k127_817743_5 - - - - 0.00000000000000000000000000000000000000000000000000001093 192.0
HFD3_k127_817743_6 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate - - - 0.00000000000000000000000000006084 121.0
HFD3_k127_817743_7 DinB family - - - 0.00000000000000001883 89.0
HFD3_k127_817743_8 Transposase - - - 0.0001746 48.0
HFD3_k127_822140_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 581.0
HFD3_k127_822140_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000208 246.0
HFD3_k127_822140_2 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000002207 181.0
HFD3_k127_826826_0 unfolded protein binding K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0018995,GO:0019219,GO:0019222,GO:0020003,GO:0022607,GO:0030430,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0033643,GO:0033646,GO:0033655,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043531,GO:0043656,GO:0043657,GO:0043933,GO:0044085,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0065010,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 4.347e-266 832.0
HFD3_k127_826826_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 574.0
HFD3_k127_826826_10 Transcriptional regulator, MerR family K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000001367 136.0
HFD3_k127_826826_11 Thioredoxin-like - - - 0.00000000000000000000000000002392 135.0
HFD3_k127_826826_12 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.0000000000000000000000000115 117.0
HFD3_k127_826826_13 - - - - 0.00000000000000000000000002524 115.0
HFD3_k127_826826_14 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000007482 111.0
HFD3_k127_826826_15 Rhomboid family - - - 0.00000000000000007054 94.0
HFD3_k127_826826_16 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000006455 91.0
HFD3_k127_826826_17 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000004807 61.0
HFD3_k127_826826_18 hydroxyisourate hydrolase activity - - - 0.0000002493 52.0
HFD3_k127_826826_2 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 416.0
HFD3_k127_826826_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 338.0
HFD3_k127_826826_4 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008931 332.0
HFD3_k127_826826_5 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 322.0
HFD3_k127_826826_6 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000763 313.0
HFD3_k127_826826_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003293 269.0
HFD3_k127_826826_8 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000004731 243.0
HFD3_k127_826826_9 Lysin motif K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000002384 244.0
HFD3_k127_851259_0 Amidohydrolase family - - - 0.0 1041.0
HFD3_k127_851259_1 aldehyde oxidase and xanthine dehydrogenase a b hammerhead K11177 - 1.17.1.4 4.865e-290 911.0
HFD3_k127_851259_10 cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 321.0
HFD3_k127_851259_11 prohibitin homologues - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 306.0
HFD3_k127_851259_12 PFAM acyl-CoA dehydrogenase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001252 271.0
HFD3_k127_851259_13 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000001014 256.0
HFD3_k127_851259_14 PFAM Haloacid dehalogenase domain protein hydrolase K01560,K07025 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000008056 246.0
HFD3_k127_851259_15 Domain of unknown function (DUF4922) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000147 253.0
HFD3_k127_851259_16 2Fe-2S -binding K13483 - - 0.000000000000000000000000000000000000000000000000000000000000001231 224.0
HFD3_k127_851259_17 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000001126 215.0
HFD3_k127_851259_18 Protein of unknown function (DUF1326) - - - 0.0000000000000000000000000000000000000000000000000000000000003665 220.0
HFD3_k127_851259_19 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000646 228.0
HFD3_k127_851259_2 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 4.024e-260 820.0
HFD3_k127_851259_20 Nucleotidyl transferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000009402 216.0
HFD3_k127_851259_21 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000001288 198.0
HFD3_k127_851259_22 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000802 167.0
HFD3_k127_851259_23 - - - - 0.0000000000000000000000000000000001004 141.0
HFD3_k127_851259_25 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000001285 121.0
HFD3_k127_851259_26 Protein of unknown function (DUF1460) - - - 0.000000000000000000008067 102.0
HFD3_k127_851259_27 Frataxin-like domain K06202 - - 0.000000000000000006975 87.0
HFD3_k127_851259_28 NfeD-like C-terminal, partner-binding - - - 0.0000000000000001566 87.0
HFD3_k127_851259_29 - - - - 0.000000000001459 74.0
HFD3_k127_851259_3 PFAM Type II secretion system protein E K02454,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 514.0
HFD3_k127_851259_30 Acetyltransferase (GNAT) domain - - - 0.00000002615 62.0
HFD3_k127_851259_31 - - - - 0.0005322 47.0
HFD3_k127_851259_4 Peptidase family S58 K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 495.0
HFD3_k127_851259_5 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007907 471.0
HFD3_k127_851259_6 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 429.0
HFD3_k127_851259_7 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 385.0
HFD3_k127_851259_8 Molybdopterin dehydrogenase K11178 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007167 379.0
HFD3_k127_851259_9 Lycopene cyclase protein K10960,K21401 - 1.3.1.111,1.3.1.83,1.3.99.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 336.0
HFD3_k127_873540_0 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000352 208.0
HFD3_k127_873540_1 galactose-6-phosphate isomerase activity K00761,K01808 - 2.4.2.9,5.3.1.6 0.0000000000000000000000000000000000000000000001224 175.0
HFD3_k127_873540_2 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000003648 142.0
HFD3_k127_882125_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 567.0
HFD3_k127_882125_1 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 551.0
HFD3_k127_882125_10 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003108 258.0
HFD3_k127_882125_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000003522 238.0
HFD3_k127_882125_12 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000007298 218.0
HFD3_k127_882125_13 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000426 182.0
HFD3_k127_882125_14 Capsular polysaccharide biosynthesis protein CapK - - - 0.000000000000000000000000000000000000000008961 171.0
HFD3_k127_882125_15 Domain of unknown function (DUF4142) K08995 - - 0.0000000000000000000000000000000001834 140.0
HFD3_k127_882125_16 Di-glucose binding within endoplasmic reticulum - - - 0.0000000000000000000000000003294 134.0
HFD3_k127_882125_18 biosynthesis protein K08253 - 2.7.10.2 0.00000000000000000000000001647 120.0
HFD3_k127_882125_19 O-Antigen ligase - - - 0.0000000000000002243 93.0
HFD3_k127_882125_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 528.0
HFD3_k127_882125_20 Chain-length determining protein - - - 0.000000000000001711 90.0
HFD3_k127_882125_21 Periplasmic protein involved in polysaccharide export K01991 - - 0.00000000004876 73.0
HFD3_k127_882125_22 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.00000002157 56.0
HFD3_k127_882125_3 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 382.0
HFD3_k127_882125_4 AAA domain K07028 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 381.0
HFD3_k127_882125_5 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 359.0
HFD3_k127_882125_6 transferase activity, transferring glycosyl groups K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 342.0
HFD3_k127_882125_7 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007674 317.0
HFD3_k127_882125_8 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007195 310.0
HFD3_k127_882125_9 Heparinase II/III N-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000314 303.0
HFD3_k127_889856_0 4Fe-4S dicluster domain K00184 - - 0.0 1066.0
HFD3_k127_889856_1 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005625 306.0
HFD3_k127_896917_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 3.32e-311 971.0
HFD3_k127_896917_1 cellulose binding - - - 5.544e-226 703.0
HFD3_k127_896917_10 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 377.0
HFD3_k127_896917_11 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 366.0
HFD3_k127_896917_12 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K21310 - 2.1.1.334 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004962 356.0
HFD3_k127_896917_13 HlyD family secretion protein K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 344.0
HFD3_k127_896917_14 galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008292 297.0
HFD3_k127_896917_15 Phosphoribosyl transferase domain K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000201 276.0
HFD3_k127_896917_16 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001354 252.0
HFD3_k127_896917_17 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003964 243.0
HFD3_k127_896917_18 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000601 216.0
HFD3_k127_896917_19 3-demethylubiquinone-9 3-methyltransferase K04750 - - 0.00000000000000000000000000000000000000000000000000000000008714 206.0
HFD3_k127_896917_2 Erythromycin esterase - - - 7.67e-199 628.0
HFD3_k127_896917_20 translation initiation factor activity K06996 - - 0.00000000000000000000000000000000000000000000000000000002564 199.0
HFD3_k127_896917_21 bacterial OsmY and nodulation domain - - - 0.00000000000000000000000000000000000000000000000000000003993 204.0
HFD3_k127_896917_22 - - - - 0.0000000000000000000000000000000000000000000000000000004919 201.0
HFD3_k127_896917_23 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000000005798 194.0
HFD3_k127_896917_24 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000002027 179.0
HFD3_k127_896917_25 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000001121 186.0
HFD3_k127_896917_26 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.000000000000000000000000000000000000000000001052 169.0
HFD3_k127_896917_28 - - - - 0.000000000000000000000000000000000000000000005186 176.0
HFD3_k127_896917_29 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000003847 162.0
HFD3_k127_896917_3 ATPase, P-type (transporting), HAD superfamily, subfamily IC - - - 2.12e-196 644.0
HFD3_k127_896917_30 YCII-related domain - - - 0.0000000000000000000000000000000000000001151 153.0
HFD3_k127_896917_32 Mo-molybdopterin cofactor metabolic process K03636,K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000001564 152.0
HFD3_k127_896917_33 LexA-binding, inner membrane-associated putative hydrolase K07038 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000002173 141.0
HFD3_k127_896917_34 pyridoxamine 5'-phosphate K07005 - - 0.00000000000000000000000000000000002963 140.0
HFD3_k127_896917_37 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000003145 129.0
HFD3_k127_896917_38 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000001977 128.0
HFD3_k127_896917_39 Universal stress protein family K07090 - - 0.0000000000000000000000005407 116.0
HFD3_k127_896917_4 PFAM Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 588.0
HFD3_k127_896917_40 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000000000008086 115.0
HFD3_k127_896917_41 Tyrosine phosphatase family - - - 0.00000000000000000000001035 109.0
HFD3_k127_896917_42 Universal stress protein family K07090 - - 0.00000000000000000000005703 109.0
HFD3_k127_896917_44 Universal stress protein - - - 0.00000000000000000001979 96.0
HFD3_k127_896917_45 Universal stress protein family - - - 0.0000000000000000001549 99.0
HFD3_k127_896917_46 AMP binding - - - 0.0000000000000000009418 97.0
HFD3_k127_896917_47 - - - - 0.000000000001138 70.0
HFD3_k127_896917_48 AMP binding - - - 0.0000000005957 70.0
HFD3_k127_896917_5 RNA polymerase, sigma subunit, ECF family K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004707 572.0
HFD3_k127_896917_50 Domain of unknown function (DUF4956) - - - 0.000000001877 69.0
HFD3_k127_896917_51 COG0457 FOG TPR repeat - - - 0.0000001455 63.0
HFD3_k127_896917_52 PFAM Uncharacterised protein family UPF0027 K14415 - 6.5.1.3 0.000000578 54.0
HFD3_k127_896917_53 von Willebrand factor, type A K07114 - - 0.0000201 56.0
HFD3_k127_896917_54 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00009891 54.0
HFD3_k127_896917_6 SMART PAS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 571.0
HFD3_k127_896917_7 Cellulase (glycosyl hydrolase family 5) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 526.0
HFD3_k127_896917_8 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 460.0
HFD3_k127_896917_9 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008108 395.0
HFD3_k127_907968_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 5.647e-262 817.0
HFD3_k127_907968_1 FtsX-like permease family - - - 2.312e-217 717.0
HFD3_k127_907968_10 Belongs to the serpin family K13963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007412 323.0
HFD3_k127_907968_11 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006901 307.0
HFD3_k127_907968_12 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K02003,K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004935 279.0
HFD3_k127_907968_13 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - - 0.00000000000000000000000000000000007056 139.0
HFD3_k127_907968_14 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - - 0.0000000000000000000000000000000001876 134.0
HFD3_k127_907968_15 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000001678 130.0
HFD3_k127_907968_16 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.000000000000000000000003284 111.0
HFD3_k127_907968_17 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000005904 68.0
HFD3_k127_907968_18 Hep Hag repeat protein K21449 - - 0.00002358 49.0
HFD3_k127_907968_2 COG1012 NAD-dependent aldehyde - - - 1.426e-208 658.0
HFD3_k127_907968_3 WD40 domain protein beta Propeller K12132 - 2.7.11.1 4.387e-201 657.0
HFD3_k127_907968_4 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009822 576.0
HFD3_k127_907968_5 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K00219 - 1.3.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 488.0
HFD3_k127_907968_6 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 475.0
HFD3_k127_907968_7 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 474.0
HFD3_k127_907968_8 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 396.0
HFD3_k127_907968_9 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007967 353.0
HFD3_k127_937986_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 5.813e-278 887.0
HFD3_k127_937986_1 GTP-binding protein TypA K06207 - - 1.281e-266 839.0
HFD3_k127_937986_10 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 537.0
HFD3_k127_937986_11 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006635 515.0
HFD3_k127_937986_12 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 460.0
HFD3_k127_937986_13 coenzyme F420 hydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 454.0
HFD3_k127_937986_14 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005899 398.0
HFD3_k127_937986_15 involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 384.0
HFD3_k127_937986_16 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 379.0
HFD3_k127_937986_17 beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 358.0
HFD3_k127_937986_18 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 356.0
HFD3_k127_937986_19 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 336.0
HFD3_k127_937986_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 3.221e-255 821.0
HFD3_k127_937986_20 PFAM intradiol ring-cleavage dioxygenase K00449 - 1.13.11.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005406 304.0
HFD3_k127_937986_21 3-oxo-5-alpha-steroid 4-dehydrogenase K12343 - 1.3.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008387 299.0
HFD3_k127_937986_22 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 294.0
HFD3_k127_937986_23 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002244 259.0
HFD3_k127_937986_24 Family of unknown function (DUF1028) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006021 260.0
HFD3_k127_937986_25 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000002878 251.0
HFD3_k127_937986_26 PFAM Ornithine cyclodeaminase mu-crystallin K01750,K19244 - 1.4.1.1,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000001279 250.0
HFD3_k127_937986_27 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002681 250.0
HFD3_k127_937986_28 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009664 239.0
HFD3_k127_937986_29 electron transfer activity K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000003377 249.0
HFD3_k127_937986_3 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 2.572e-233 736.0
HFD3_k127_937986_30 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000007031 235.0
HFD3_k127_937986_31 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000001903 250.0
HFD3_k127_937986_32 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001487 241.0
HFD3_k127_937986_33 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443,K16786,K16787 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000001846 230.0
HFD3_k127_937986_34 von Willebrand factor (vWF) type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000003933 228.0
HFD3_k127_937986_35 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000004888 228.0
HFD3_k127_937986_36 TIGRFAM geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000000000000000000001363 225.0
HFD3_k127_937986_37 Histidine kinase-like ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000002153 220.0
HFD3_k127_937986_38 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000000000000000000000000000000000004782 211.0
HFD3_k127_937986_39 GAF domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000001812 214.0
HFD3_k127_937986_4 PFAM Magnesium chelatase, ChlI subunit K07391 - - 1.278e-222 700.0
HFD3_k127_937986_40 - - - - 0.000000000000000000000000000000000000000000000000000005249 199.0
HFD3_k127_937986_41 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000002644 199.0
HFD3_k127_937986_42 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000003271 211.0
HFD3_k127_937986_43 DinB superfamily K07552 - - 0.0000000000000000000000000000000000000000000000000007114 188.0
HFD3_k127_937986_44 Transposase IS200 like - - - 0.000000000000000000000000000000000000000000000002551 185.0
HFD3_k127_937986_45 HD domain - - - 0.000000000000000000000000000000000000000000000004689 189.0
HFD3_k127_937986_46 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000001789 177.0
HFD3_k127_937986_47 SNARE associated Golgi protein K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000172 169.0
HFD3_k127_937986_48 - - - - 0.000000000000000000000000000000000000000000139 173.0
HFD3_k127_937986_49 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K15725 - - 0.0000000000000000000000000000000000000000002974 176.0
HFD3_k127_937986_5 Nickel-dependent hydrogenase - - - 1.35e-217 681.0
HFD3_k127_937986_50 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.0000000000000000000000000000000000000002102 160.0
HFD3_k127_937986_51 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000001923 157.0
HFD3_k127_937986_52 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000617 158.0
HFD3_k127_937986_53 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000005346 145.0
HFD3_k127_937986_54 Hydrogenase maturation protease - - - 0.000000000000000000000000000000005694 133.0
HFD3_k127_937986_55 von Willebrand factor, type A - - - 0.00000000000000000000000000000007126 145.0
HFD3_k127_937986_56 PFAM Transposase IS200 like K07491 - - 0.000000000000000000000000000000666 126.0
HFD3_k127_937986_57 outer membrane efflux protein - - - 0.000000000000000000000000000001315 138.0
HFD3_k127_937986_58 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00000000000000000000000000008223 133.0
HFD3_k127_937986_59 cell redox homeostasis K02199 - - 0.0000000000000000000000000004797 120.0
HFD3_k127_937986_6 Belongs to the citrate synthase family K01647 - 2.3.3.1 2.683e-215 676.0
HFD3_k127_937986_60 PFAM Phosphoglycerate mutase - - - 0.000000000000000000000000001765 124.0
HFD3_k127_937986_61 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.0000000000000000000000001005 109.0
HFD3_k127_937986_62 Pfam:N_methyl_2 - - - 0.000000000000000000000001301 109.0
HFD3_k127_937986_63 PAP2 superfamily - - - 0.0000000000000000000001065 109.0
HFD3_k127_937986_64 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000007559 109.0
HFD3_k127_937986_65 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000008137 101.0
HFD3_k127_937986_66 Pfam:N_methyl_2 - - - 0.0000000000000000003933 94.0
HFD3_k127_937986_67 Domain of unknown function (DUF4149) - - - 0.00000000000000003236 88.0
HFD3_k127_937986_68 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000007781 90.0
HFD3_k127_937986_69 Pfam:N_methyl_2 - - - 0.000000000000003115 83.0
HFD3_k127_937986_7 Penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 627.0
HFD3_k127_937986_70 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.00000000000008181 74.0
HFD3_k127_937986_71 Domain of unknown function (DUF4384) - - - 0.0000000000001433 79.0
HFD3_k127_937986_72 sigma factor antagonist activity K04757 - 2.7.11.1 0.000000000008788 79.0
HFD3_k127_937986_73 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000001651 68.0
HFD3_k127_937986_74 Domain of unknown function (DUF4384) - - - 0.00000007205 63.0
HFD3_k127_937986_75 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 0.000003514 54.0
HFD3_k127_937986_77 Ring finger domain K10635 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005515,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0008285,GO:0009056,GO:0009057,GO:0009791,GO:0009908,GO:0009987,GO:0010498,GO:0016567,GO:0016740,GO:0019538,GO:0019787,GO:0019899,GO:0019941,GO:0022414,GO:0030163,GO:0031624,GO:0032446,GO:0032501,GO:0032502,GO:0036211,GO:0040008,GO:0042127,GO:0043161,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044390,GO:0045926,GO:0046620,GO:0046621,GO:0048367,GO:0048437,GO:0048518,GO:0048519,GO:0048523,GO:0048608,GO:0048638,GO:0048640,GO:0048731,GO:0048831,GO:0048856,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0051094,GO:0051239,GO:0051240,GO:0051241,GO:0051603,GO:0051865,GO:0061458,GO:0061630,GO:0061659,GO:0065007,GO:0070647,GO:0071704,GO:0090567,GO:0099402,GO:0140096,GO:1900055,GO:1900057,GO:1901564,GO:1901565,GO:1901575,GO:1905623,GO:2000024,GO:2000026 2.3.2.27 0.0002592 49.0
HFD3_k127_937986_8 D-aminoacylase domain protein K01465,K06015 - 3.5.1.81,3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006995 612.0
HFD3_k127_937986_9 PFAM CobN Magnesium Chelatase K02230,K03403 - 6.6.1.1,6.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007446 555.0
HFD3_k127_962771_0 PQQ-like domain K05889 - 1.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 318.0
HFD3_k127_962771_1 DinB family - - - 0.00000000000000000000000000000000000000000000000000000000007613 210.0
HFD3_k127_962771_2 thiolester hydrolase activity K07000 - - 0.0000000000000000000000000000000000000000000007115 175.0
HFD3_k127_962771_3 Oxidoreductase activity. It is involved in the biological process described with metabolic process - - - 0.000000000000000000000000000006397 120.0
HFD3_k127_962771_4 DinB family - - - 0.0000000000000000000000001049 115.0
HFD3_k127_962771_5 Beta-lactamase - - - 0.0000000000000006574 85.0
HFD3_k127_968818_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 2.404e-197 647.0
HFD3_k127_968818_1 Histidine kinase K02480,K07683 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 544.0
HFD3_k127_968818_2 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006689 398.0
HFD3_k127_968818_3 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000003848 216.0
HFD3_k127_968818_4 response regulator K02282 - - 0.00000000000000000000000000000009138 127.0
HFD3_k127_968818_5 domain protein - - - 0.00000001063 63.0
HFD3_k127_990712_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 9.022e-249 781.0
HFD3_k127_990712_1 Peptidase family M49 - - - 1.681e-199 636.0
HFD3_k127_990712_10 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family K01406,K13276,K20276 - 3.4.24.40 0.0000000001887 74.0
HFD3_k127_990712_11 Tetratricopeptide repeat - - - 0.0003471 54.0
HFD3_k127_990712_12 Peptidase family M1 domain - - - 0.0007948 53.0
HFD3_k127_990712_2 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 452.0
HFD3_k127_990712_3 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008232 382.0
HFD3_k127_990712_4 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 346.0
HFD3_k127_990712_5 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 351.0
HFD3_k127_990712_6 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000003705 258.0
HFD3_k127_990712_7 Palmitoyl-monogalactosyldiacylglycerol delta-7 desaturase, chloroplastic-like K00507,K20416 - 1.14.19.1,1.14.19.42 0.00000000000000000000000000000000000000001514 166.0
HFD3_k127_990712_8 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000001442 111.0
HFD3_k127_990712_9 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.00000000000000000000000006387 112.0