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Overview

ID MAG01690
Name HFD3_bin.32
Sample SMP0045
Taxonomy
Kingdom Bacteria
Phylum Chloroflexota
Class Limnocylindria
Order Limnocylindrales
Family CSP1-4
Genus UBA5189
Species
Assembly information
Completeness (%) 74.08
Contamination (%) 0.42
GC content (%) 71.0
N50 (bp) 19,946
Genome size (bp) 2,484,183

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2160

Gene name Description KEGG GOs EC E-value Score Sequence
HFD3_k127_1018419_0 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000002251 135.0
HFD3_k127_1018419_1 acetyltransferase - - - 0.00000000000000000006343 99.0
HFD3_k127_1018419_2 oligosaccharyl transferase activity - - - 0.0000000000001672 83.0
HFD3_k127_1037882_0 Catalyzes the conversion of dihydroorotate to orotate K00254,K17828 - 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 484.0
HFD3_k127_1037882_1 PFAM PrpF protein K20451 - 5.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 389.0
HFD3_k127_1037882_10 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000001123 227.0
HFD3_k127_1037882_11 aspartate dehydrogenase activity K06989 - 1.4.1.21 0.0000000000000000000000000000000000000000000000000000000000212 223.0
HFD3_k127_1037882_12 Domain of unknown function (DUF3291) - - - 0.00000000000000000000000000000000000000000003401 171.0
HFD3_k127_1037882_13 FCD - - - 0.00000000000000000000000000000000000000000006424 168.0
HFD3_k127_1037882_14 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000001082 175.0
HFD3_k127_1037882_15 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000001568 149.0
HFD3_k127_1037882_16 Asparaginase K01424 - 3.5.1.1 0.000000000000000000000000000000000012 138.0
HFD3_k127_1037882_17 peptidase - - - 0.000000000000000000000000000000004958 141.0
HFD3_k127_1037882_18 Methyltransferase K10218 - 4.1.3.17 0.0000000000000000000000000000004399 138.0
HFD3_k127_1037882_19 NMT1/THI5 like K02051 - - 0.00000000000000000000000000333 124.0
HFD3_k127_1037882_2 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate and vanillate K01612,K16874 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044464 4.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006662 358.0
HFD3_k127_1037882_20 Catalyzes the conversion of maleate to fumarate K01799 - 5.2.1.1 0.000000000000000000005543 102.0
HFD3_k127_1037882_21 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.000001043 61.0
HFD3_k127_1037882_23 Protein of unknown function (DUF4242) - - - 0.00000128 54.0
HFD3_k127_1037882_24 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000001824 53.0
HFD3_k127_1037882_3 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 353.0
HFD3_k127_1037882_4 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 302.0
HFD3_k127_1037882_5 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 297.0
HFD3_k127_1037882_6 Protein of unknown function DUF262 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003893 283.0
HFD3_k127_1037882_7 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001263 265.0
HFD3_k127_1037882_8 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000001062 246.0
HFD3_k127_1037882_9 L11 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000006025 225.0
HFD3_k127_1040382_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 346.0
HFD3_k127_1040382_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000007716 64.0
HFD3_k127_1104470_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 556.0
HFD3_k127_1104470_1 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000000000007394 211.0
HFD3_k127_1104470_2 L-lysine 6-monooxygenase (NADPH-requiring) K07222 - - 0.000000000000000000000000000000003833 134.0
HFD3_k127_1104470_3 SnoaL-like domain K06893 - - 0.0000000000000000002346 93.0
HFD3_k127_1104470_4 Septum formation - - - 0.0000000000009182 77.0
HFD3_k127_1107588_0 Phospholipase D. Active site motifs. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003497 363.0
HFD3_k127_1107588_1 Dual-action HEIGH metallo-peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005096 251.0
HFD3_k127_1107588_2 Serine hydrolase - - - 0.000000000000000000000000000005873 134.0
HFD3_k127_1107588_3 DNA-binding transcriptional activator of the SARP family - - - 0.0000000000000000000000001539 119.0
HFD3_k127_1107588_4 WD40 repeat, subgroup - - - 0.000000002445 67.0
HFD3_k127_1107588_5 Tetratricopeptide repeat - - - 0.00001745 58.0
HFD3_k127_116948_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 443.0
HFD3_k127_116948_1 Transcriptional regulator - - - 0.00000001873 62.0
HFD3_k127_1393779_0 glutamate synthase, alpha subunit domain protein K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 6.048e-300 970.0
HFD3_k127_1393779_1 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 6.656e-211 689.0
HFD3_k127_1393779_2 Transport permease protein K01992 - - 0.00000000000000000000000000284 114.0
HFD3_k127_144819_0 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003649 258.0
HFD3_k127_144819_1 TIGRFAM arsenite-activated ATPase ArsA K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000005462 254.0
HFD3_k127_144819_2 Peptidase A4 family - - - 0.0000000000000000000000000000000000000000000000000006114 196.0
HFD3_k127_144819_3 - - - - 0.0000617 55.0
HFD3_k127_1504095_0 Lantibiotic biosynthesis dehydratase C-term K20483 - - 4.11e-249 804.0
HFD3_k127_1504095_1 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000303 284.0
HFD3_k127_1504095_2 L-asparaginase II K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000000000000000000001656 229.0
HFD3_k127_1504095_3 Cytochrome C biogenesis protein K05516 - - 0.0000006717 61.0
HFD3_k127_151992_0 metallopeptidase activity K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 498.0
HFD3_k127_151992_1 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 393.0
HFD3_k127_151992_10 nUDIX hydrolase K01515,K03574,K03801,K08310 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008828,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017144,GO:0018130,GO:0019177,GO:0019438,GO:0019752,GO:0034641,GO:0042364,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0046872,GO:0047429,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.1.181,3.6.1.13,3.6.1.55,3.6.1.67 0.000000000000122 77.0
HFD3_k127_151992_2 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006376 301.0
HFD3_k127_151992_3 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001184 266.0
HFD3_k127_151992_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000005579 222.0
HFD3_k127_151992_5 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000619 205.0
HFD3_k127_151992_6 Cyclic-di-AMP receptor - - - 0.000000000000000000000000000000006647 134.0
HFD3_k127_151992_7 peptidase U62, modulator of DNA gyrase - - - 0.00000000000000000000000000000009511 144.0
HFD3_k127_151992_8 Diguanylate cyclase - - - 0.00000000000000000000000004043 120.0
HFD3_k127_1539887_0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009714 263.0
HFD3_k127_1539887_1 PFAM FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001898 263.0
HFD3_k127_1539887_2 Cytochrome C and Quinol oxidase polypeptide I K04561 - 1.7.2.5 0.000000000000000000000000000000000000000006096 158.0
HFD3_k127_1539887_3 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000001009 127.0
HFD3_k127_1539887_4 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000005188 111.0
HFD3_k127_1560990_0 Mo-co oxidoreductase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 496.0
HFD3_k127_1560990_1 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 336.0
HFD3_k127_1560990_10 RDD family - - - 0.000000000000000000000000002372 123.0
HFD3_k127_1560990_11 ACT domain protein - - - 0.000000000000000000004849 102.0
HFD3_k127_1560990_12 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000002878 103.0
HFD3_k127_1560990_13 F420H(2)-dependent quinone reductase - - - 0.000000000000000002113 101.0
HFD3_k127_1560990_14 PFAM sigma-70 region 2 domain protein K03088 - - 0.000000000000005817 88.0
HFD3_k127_1560990_15 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0003393 50.0
HFD3_k127_1560990_2 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K00375 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001468 264.0
HFD3_k127_1560990_3 TPM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007378 288.0
HFD3_k127_1560990_4 PspA/IM30 family K03969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005143 256.0
HFD3_k127_1560990_5 Histidine phosphatase superfamily (branch 1) - - - 0.00000000000000000000000000000000000000000000000000000000000000005752 234.0
HFD3_k127_1560990_6 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000000000000000000009624 233.0
HFD3_k127_1560990_7 SelR domain K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000002556 186.0
HFD3_k127_1560990_8 Transcriptional regulator - - - 0.00000000000000000000000000000000000002504 160.0
HFD3_k127_1560990_9 regulation of RNA biosynthetic process - - - 0.00000000000000000000000000007569 123.0
HFD3_k127_1597675_0 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 392.0
HFD3_k127_1597675_1 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008438 303.0
HFD3_k127_1597675_10 Iron dependent repressor, N-terminal DNA binding domain - GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000004928 59.0
HFD3_k127_1597675_2 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000001238 243.0
HFD3_k127_1597675_3 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K04091 - 1.14.14.5 0.0000000000000000000000000000000000000000000000000000000000000000002633 241.0
HFD3_k127_1597675_4 ECF sigma factor K03088 - - 0.00000000000000000000000000001344 126.0
HFD3_k127_1597675_5 ArsC family - - - 0.0000000000000000000000000000586 120.0
HFD3_k127_1597675_6 Secreted repeat of unknown function - - - 0.00000000000000000000000001877 119.0
HFD3_k127_1597675_7 Rieske [2Fe-2S] domain - - - 0.000000000002097 76.0
HFD3_k127_1597675_8 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.00000000002567 70.0
HFD3_k127_1597675_9 SIS domain K00820 - 2.6.1.16 0.0000000001123 74.0
HFD3_k127_1637734_0 PNKP adenylyltransferase domain, ligase domain K01090 - 3.1.3.16 0.000000000000000000000000000009395 123.0
HFD3_k127_1637734_1 COG1512 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.000166 55.0
HFD3_k127_1778504_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009601 443.0
HFD3_k127_1778504_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007769 425.0
HFD3_k127_1778504_2 Sigma-54 interaction domain K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 381.0
HFD3_k127_1778504_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 404.0
HFD3_k127_1778504_4 SMART Nucleotide binding protein, PINc - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 307.0
HFD3_k127_1778504_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000005727 205.0
HFD3_k127_1778504_6 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.000000000000000000000000000000005507 134.0
HFD3_k127_1816049_0 xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 3.242e-243 781.0
HFD3_k127_1816049_1 MmgE/PrpD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007211 520.0
HFD3_k127_1816049_10 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004501 280.0
HFD3_k127_1816049_11 CO dehydrogenase flavoprotein domain protein K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000004606 264.0
HFD3_k127_1816049_12 Branched-chain amino acid transport system / permease component K10439,K10440 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003539 254.0
HFD3_k127_1816049_13 Methionine synthase B12-binding module cap domain protein - - - 0.00000000000000000000000000000000000000000000000000000000001376 214.0
HFD3_k127_1816049_14 [2Fe-2S] binding domain K03518,K19819 - 1.2.5.3,1.5.99.4 0.000000000000000000000000000000000000000000000000003028 193.0
HFD3_k127_1816049_15 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.00000000000000000000000000000000000000000000002724 181.0
HFD3_k127_1816049_16 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000006182 175.0
HFD3_k127_1816049_17 asparaginase K01424 - 3.5.1.1 0.00000000000000000000000000000000000000002225 166.0
HFD3_k127_1816049_18 PFAM major facilitator superfamily MFS_1 K03449 - - 0.000000000000000000000000000000000000001333 164.0
HFD3_k127_1816049_19 regulatory protein GntR HTH - - - 0.000000000000000000000000000000000002863 154.0
HFD3_k127_1816049_2 PFAM transcriptional regulator domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000442 527.0
HFD3_k127_1816049_20 Zinc finger domain - - - 0.000000000000000000000000000000005676 143.0
HFD3_k127_1816049_21 oxidoreductase activity, acting on CH-OH group of donors K09386 - - 0.000000000000000000000000000128 123.0
HFD3_k127_1816049_22 ABC-type sugar transport system periplasmic component K03549,K10439,K10910,K21429 GO:0006355,GO:0006810,GO:0008150,GO:0008643,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051179,GO:0051234,GO:0051252,GO:0060255,GO:0065007,GO:0071702,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000001492 129.0
HFD3_k127_1816049_23 PAS domain - - - 0.00000000000000000000001231 108.0
HFD3_k127_1816049_24 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000539 94.0
HFD3_k127_1816049_25 Domain of unknown function (DUF296) - - - 0.000000000000000006567 94.0
HFD3_k127_1816049_26 Rdx family K07401 - - 0.00000000006138 68.0
HFD3_k127_1816049_27 - - - - 0.00001814 56.0
HFD3_k127_1816049_3 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008069 459.0
HFD3_k127_1816049_4 PFAM isocitrate isopropylmalate dehydrogenase K00052,K07246 - 1.1.1.83,1.1.1.85,1.1.1.93,4.1.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 427.0
HFD3_k127_1816049_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 421.0
HFD3_k127_1816049_6 import. Responsible for energy coupling to the transport system K10441 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008605 363.0
HFD3_k127_1816049_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 304.0
HFD3_k127_1816049_8 Amidohydrolase family K01464 - 3.5.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001228 291.0
HFD3_k127_1816049_9 Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004173 280.0
HFD3_k127_1817897_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005567 358.0
HFD3_k127_1817897_1 Protein of unknown function (DUF1385) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009797 256.0
HFD3_k127_1817897_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000003822 185.0
HFD3_k127_1817897_3 HAD-superfamily hydrolase, subfamily IIB - - - 0.00000000000000000000000000000001565 142.0
HFD3_k127_1867649_0 TIGRFAM Translation elongation factor K02355 - - 1.849e-198 641.0
HFD3_k127_1867649_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000789 290.0
HFD3_k127_1867649_2 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000002477 261.0
HFD3_k127_1867649_3 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000003839 168.0
HFD3_k127_1867649_4 EamA-like transporter family - - - 0.00000000000000000000000000000000000000001584 156.0
HFD3_k127_1867649_5 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000008474 140.0
HFD3_k127_189216_0 PFAM AAA ATPase central domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001154 257.0
HFD3_k127_189216_1 Pkd domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001331 261.0
HFD3_k127_189216_2 Pkd domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000008754 244.0
HFD3_k127_189216_3 Bacterial regulatory proteins, luxR family - - - 0.0000000000000000000000000000000000000000000000000000000000000002557 239.0
HFD3_k127_189216_4 WD40-like Beta Propeller Repeat - - - 0.00000000000000009528 93.0
HFD3_k127_1916239_0 Alpha amylase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 450.0
HFD3_k127_1916239_1 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004581 254.0
HFD3_k127_1986483_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1034.0
HFD3_k127_1986483_1 PERMEase K06901 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 605.0
HFD3_k127_1986483_10 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000002801 244.0
HFD3_k127_1986483_11 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000009305 189.0
HFD3_k127_1986483_12 Acid phosphatase homologues - - - 0.0000000000000000000000000000000000000000000001654 176.0
HFD3_k127_1986483_13 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000001795 175.0
HFD3_k127_1986483_14 Major Facilitator Superfamily - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000002235 167.0
HFD3_k127_1986483_15 Oxidoreductase NAD-binding domain K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000003946 159.0
HFD3_k127_1986483_16 Xanthine uracil vitamin C permease K06901 - - 0.00000000000000000000000000000000000004718 149.0
HFD3_k127_1986483_17 Transcriptional regulator, Crp Fnr family - - - 0.00000000000000000000000000000000002393 146.0
HFD3_k127_1986483_18 Diacylglycerol kinase catalytic domain (presumed) - - - 0.0000000000000000000000000007307 130.0
HFD3_k127_1986483_19 acetyltransferase K06975 - - 0.0000000000000000001556 93.0
HFD3_k127_1986483_2 Succinyl-CoA synthetase, alpha subunit K02381 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005668 531.0
HFD3_k127_1986483_20 Transglycosylase associated protein - - - 0.000000000000000005415 87.0
HFD3_k127_1986483_21 Protein of unknown function (DUF2877) - - - 0.0000000000000004749 89.0
HFD3_k127_1986483_3 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 461.0
HFD3_k127_1986483_4 spermidine synthase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 457.0
HFD3_k127_1986483_5 FdrA family K02381 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007418 405.0
HFD3_k127_1986483_6 Belongs to the carbamate kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 352.0
HFD3_k127_1986483_7 PFAM Purine catabolism regulatory protein-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004747 333.0
HFD3_k127_1986483_8 oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007586 319.0
HFD3_k127_1986483_9 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 313.0
HFD3_k127_2220561_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 2.097e-257 810.0
HFD3_k127_2220561_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 569.0
HFD3_k127_2220561_10 HpcH/HpaI aldolase/citrate lyase family K02510 - 4.1.2.52 0.000000000000000000000000000000000000000000000000000000000000000001295 235.0
HFD3_k127_2220561_11 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000002829 171.0
HFD3_k127_2220561_12 PFAM GCN5-related N-acetyltransferase K03823 - 2.3.1.183 0.000000000000000000000000000000000000000005399 168.0
HFD3_k127_2220561_13 EamA-like transporter family - - - 0.000000000000000000000000000000000002363 150.0
HFD3_k127_2220561_14 Transport permease protein K01992 - - 0.00000000000000000000000000002084 133.0
HFD3_k127_2220561_16 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000009769 101.0
HFD3_k127_2220561_17 PFAM CBS domain containing protein - - - 0.000000000000000007384 90.0
HFD3_k127_2220561_19 response regulator, receiver - - - 0.00001542 54.0
HFD3_k127_2220561_2 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004557 529.0
HFD3_k127_2220561_20 Polyketide cyclase / dehydrase and lipid transport - - - 0.0001131 54.0
HFD3_k127_2220561_3 homogentisate 1,2-dioxygenase K00451 - 1.13.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006613 499.0
HFD3_k127_2220561_4 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 469.0
HFD3_k127_2220561_5 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 359.0
HFD3_k127_2220561_6 Creatinase/Prolidase N-terminal domain K01271,K01274 - 3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 330.0
HFD3_k127_2220561_7 TIGRFAM daunorubicin resistance ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001304 293.0
HFD3_k127_2220561_8 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001813 277.0
HFD3_k127_2220561_9 Fumarylacetoacetate (FAA) hydrolase family K16171 - 3.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000002286 249.0
HFD3_k127_227498_0 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 587.0
HFD3_k127_227498_1 protein related to plant photosystem II stability assembly factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 489.0
HFD3_k127_227498_2 PFAM DGPFAETKE family protein - - - 0.000000000000000000000000000000000000000000000000001243 186.0
HFD3_k127_227498_3 Domain of unknown function (DUF1905) - - - 0.00000000000000000000000000000000000000000000000003823 182.0
HFD3_k127_227498_4 guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000007028 176.0
HFD3_k127_227498_5 YCII-related domain - - - 0.0000000000000000000000000000003314 126.0
HFD3_k127_227498_6 Secreted repeat of unknown function - - - 0.0000000000000000000000007207 108.0
HFD3_k127_227498_7 ThiS family - - - 0.00000000000000000000001451 105.0
HFD3_k127_227498_8 PFAM intradiol ring-cleavage dioxygenase - - - 0.000000578 54.0
HFD3_k127_2275587_0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 310.0
HFD3_k127_2275587_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005781 286.0
HFD3_k127_2275587_2 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005156 254.0
HFD3_k127_2275587_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000004679 204.0
HFD3_k127_2275587_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000006388 152.0
HFD3_k127_2275587_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000008438 127.0
HFD3_k127_2275587_6 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000001249 85.0
HFD3_k127_2275587_7 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000007653 50.0
HFD3_k127_2283169_0 PFAM Prolyl oligopeptidase family K01303 - 3.4.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 493.0
HFD3_k127_2283169_1 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 413.0
HFD3_k127_2283169_10 Putative heavy-metal-binding - - - 0.00000000000000000000000000000000000000003382 154.0
HFD3_k127_2283169_11 ABC-type Na efflux pump, permease component K01992 - - 0.00000000000000000000000000000000001307 152.0
HFD3_k127_2283169_12 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000001436 136.0
HFD3_k127_2283169_13 Domain of unknown function (DUF4260) - - - 0.000000000000000000000002111 108.0
HFD3_k127_2283169_14 Protein of unknown function (DUF971) - - - 0.0000000000000000000004032 104.0
HFD3_k127_2283169_15 negative regulation of translational initiation K05554,K15885 - - 0.00000000000000000004802 97.0
HFD3_k127_2283169_16 ATP-dependent DNA ligase K01971 - 6.5.1.1 0.0000000000000000001258 102.0
HFD3_k127_2283169_17 F420-dependent oxidoreductase - - - 0.000000000000000005589 90.0
HFD3_k127_2283169_18 - - - - 0.0001412 49.0
HFD3_k127_2283169_19 Hint domain - - - 0.0002154 53.0
HFD3_k127_2283169_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 426.0
HFD3_k127_2283169_3 Beta-ketoacyl synthase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 338.0
HFD3_k127_2283169_4 Belongs to the PstS family K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004881 317.0
HFD3_k127_2283169_5 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001851 279.0
HFD3_k127_2283169_6 ABC transporter, ATP-binding protein K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003188 279.0
HFD3_k127_2283169_7 TIGRFAM phosphate ABC transporter K02038 - - 0.000000000000000000000000000000000000000000000000000000000006485 229.0
HFD3_k127_2283169_8 geranylgeranyl reductase activity K21401 - 1.3.99.38 0.00000000000000000000000000000000000000000000000000715 198.0
HFD3_k127_2283169_9 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000001084 184.0
HFD3_k127_2307582_0 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000001765 172.0
HFD3_k127_2307582_1 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000005334 172.0
HFD3_k127_2345126_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 464.0
HFD3_k127_2345126_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004871 368.0
HFD3_k127_2345126_10 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000198 128.0
HFD3_k127_2345126_11 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.0000000000000000000000007316 115.0
HFD3_k127_2345126_12 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000003218 96.0
HFD3_k127_2345126_13 Carbamoyl-phosphate synthetase large chain domain protein K01959 - 6.4.1.1 0.0000000007658 61.0
HFD3_k127_2345126_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 360.0
HFD3_k127_2345126_3 O-Antigen ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001443 301.0
HFD3_k127_2345126_4 reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000441 285.0
HFD3_k127_2345126_5 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000001639 215.0
HFD3_k127_2345126_6 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067,K01790,K19997 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008831,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0045226,GO:0046379,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 1.1.1.133,5.1.3.13,5.1.3.26 0.00000000000000000000000000000000000000000000000005143 191.0
HFD3_k127_2345126_7 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000003158 154.0
HFD3_k127_2345126_8 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.000000000000000000000000000000001495 136.0
HFD3_k127_2345126_9 Diguanylate cyclase - - - 0.0000000000000000000000000000001688 142.0
HFD3_k127_2381862_0 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 610.0
HFD3_k127_2381862_1 RNA ligase activity K14415,K18148 GO:0003674,GO:0003824,GO:0003909,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0030145,GO:0030312,GO:0033554,GO:0034641,GO:0042245,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 558.0
HFD3_k127_2381862_10 Archease protein family (MTH1598/TM1083) - - - 0.000000006453 66.0
HFD3_k127_2381862_2 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004791 512.0
HFD3_k127_2381862_3 phosphoribosyltransferase K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000271 277.0
HFD3_k127_2381862_4 Capsule synthesis protein K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007536 284.0
HFD3_k127_2381862_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000007445 226.0
HFD3_k127_2381862_6 phosphoribosyltransferase K07100 - - 0.0000000000000000000000000000000000000000000000000000001487 211.0
HFD3_k127_2381862_7 ABC transporter K10112 - - 0.00000000000000000000000000000000000000000003278 164.0
HFD3_k127_2381862_8 Polysaccharide deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000000502 145.0
HFD3_k127_2381862_9 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000003094 108.0
HFD3_k127_243978_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K01919,K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 6.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006385 325.0
HFD3_k127_243978_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000001337 171.0
HFD3_k127_243978_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000006013 61.0
HFD3_k127_2450449_0 Anticodon-binding domain of tRNA K01870 - 6.1.1.5 2.191e-249 784.0
HFD3_k127_2468749_0 7TM-HD extracellular K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 368.0
HFD3_k127_2468749_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000903 357.0
HFD3_k127_2468749_2 epimerase K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000005616 271.0
HFD3_k127_2468749_3 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004222 258.0
HFD3_k127_2468749_4 Yqey-like protein K09117 - - 0.00000000000000000000000000004198 124.0
HFD3_k127_2468749_5 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000001813 106.0
HFD3_k127_2468749_6 Ribosomal protein S21 K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000001032 83.0
HFD3_k127_2468749_7 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000001511 83.0
HFD3_k127_2468749_8 Phosphoesterase, PA-phosphatase related K19302 - 3.6.1.27 0.000004044 51.0
HFD3_k127_2469740_0 DEAD/H associated K03724 - - 0.0 1506.0
HFD3_k127_2469740_1 RimK-like ATP-grasp domain K03802 - 6.3.2.29,6.3.2.30 0.0 1150.0
HFD3_k127_2469740_10 PFAM amidohydrolase K01464 - 3.5.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009616 328.0
HFD3_k127_2469740_11 histone deacetylase K04768 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 324.0
HFD3_k127_2469740_12 Mur ligase middle domain K03802 - 6.3.2.29,6.3.2.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007943 330.0
HFD3_k127_2469740_13 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000004214 265.0
HFD3_k127_2469740_14 DRTGG domain K06873 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005233 263.0
HFD3_k127_2469740_15 Peptidase family S51 K13282 - 3.4.15.6 0.00000000000000000000000000000000000000000000000000000000000000000000000009288 258.0
HFD3_k127_2469740_16 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin K00365 - 1.7.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000002509 258.0
HFD3_k127_2469740_17 PFAM Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000002529 238.0
HFD3_k127_2469740_18 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000002268 237.0
HFD3_k127_2469740_19 Belongs to the FPG family K05522 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000009402 216.0
HFD3_k127_2469740_2 Malate synthase K01638 - 2.3.3.9 4.199e-226 711.0
HFD3_k127_2469740_20 PFAM DoxX family protein K16937 - 1.8.5.2 0.0000000000000000000000000000000000000000000000000000003932 203.0
HFD3_k127_2469740_21 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000008576 201.0
HFD3_k127_2469740_22 DegV family - - - 0.00000000000000000000000000000000000000000000000006644 191.0
HFD3_k127_2469740_23 Protein of unknown function (DUF3830) - - - 0.0000000000000000000000000000000000000000007642 161.0
HFD3_k127_2469740_24 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000002853 162.0
HFD3_k127_2469740_25 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000001428 157.0
HFD3_k127_2469740_26 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000001121 135.0
HFD3_k127_2469740_27 AzlC protein - - - 0.0000000000000000000000000001674 124.0
HFD3_k127_2469740_28 Evidence 2b Function of strongly homologous gene - - - 0.000000000000000000000000000508 128.0
HFD3_k127_2469740_29 - - - - 0.000000000000000000000000003636 125.0
HFD3_k127_2469740_3 Protein of unknown function, DUF255 K06888 - - 2.44e-205 679.0
HFD3_k127_2469740_30 Nudix hydrolase - - - 0.0000000000000000000000001725 123.0
HFD3_k127_2469740_31 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily K07127 - 3.5.2.17 0.00000000000000000000816 97.0
HFD3_k127_2469740_32 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - 0.0000000000000000001514 96.0
HFD3_k127_2469740_33 OHCU decarboxylase - - - 0.0000000000000002133 84.0
HFD3_k127_2469740_34 Glutamine amidotransferases class-II - - - 0.00001513 57.0
HFD3_k127_2469740_4 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 550.0
HFD3_k127_2469740_5 DNA ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007139 560.0
HFD3_k127_2469740_6 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 394.0
HFD3_k127_2469740_7 Major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 366.0
HFD3_k127_2469740_8 peptidase K01295 - 3.4.17.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000618 359.0
HFD3_k127_2469740_9 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009426 330.0
HFD3_k127_2484437_0 Glycosyl transferases group 1 K13057 - 2.4.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 439.0
HFD3_k127_2484437_1 COG3119 Arylsulfatase A and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 416.0
HFD3_k127_2484437_10 Putative regulatory protein - - - 0.0000000002 70.0
HFD3_k127_2484437_11 Virulence factor BrkB K07058 - - 0.00001428 58.0
HFD3_k127_2484437_2 Cell cycle protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 352.0
HFD3_k127_2484437_3 PFAM Binding-protein-dependent transport system inner membrane component K02025,K10233 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 318.0
HFD3_k127_2484437_4 ABC-type sugar transport system, permease component K10234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004994 304.0
HFD3_k127_2484437_5 ABC-type sugar transport system periplasmic component K10232 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006774 296.0
HFD3_k127_2484437_6 PFAM penicillin-binding protein transpeptidase K05364 - - 0.000000000000000000000000000000000000000000000000000000000000001603 248.0
HFD3_k127_2484437_7 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000002314 116.0
HFD3_k127_2484437_8 PFAM Forkhead-associated protein - - - 0.0000000000000000000000006271 117.0
HFD3_k127_2484437_9 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000002575 101.0
HFD3_k127_248445_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.448e-239 766.0
HFD3_k127_248445_1 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691 400.0
HFD3_k127_248445_2 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 330.0
HFD3_k127_248445_3 Histidine kinase-like ATPases - - - 0.0000000000000000000006522 110.0
HFD3_k127_2543541_0 Threonine dehydratase K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000001678 218.0
HFD3_k127_2543541_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000004133 82.0
HFD3_k127_2563956_0 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 4.344e-232 732.0
HFD3_k127_2563956_1 Carbamoyl-phosphate synthetase large chain domain protein K01968 - 6.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 342.0
HFD3_k127_2563956_2 Cellulose biosynthesis protein BcsQ K03496 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000006745 233.0
HFD3_k127_2563956_3 HAD-hyrolase-like - - - 0.00000000000000000000000000000000000000000000000008052 187.0
HFD3_k127_2563956_4 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000001794 168.0
HFD3_k127_2563956_5 PFAM Phospholipid glycerol acyltransferase - - - 0.00000000000000000000007416 110.0
HFD3_k127_2563956_6 UbiA prenyltransferase family - - - 0.000000000000000005925 94.0
HFD3_k127_2563956_7 PspC domain K03973 - - 0.00000000000004585 81.0
HFD3_k127_2563956_8 membrane - - - 0.000003354 59.0
HFD3_k127_2565815_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006666 601.0
HFD3_k127_2565815_1 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 441.0
HFD3_k127_2565815_10 AAA domain K01090 - 3.1.3.16 0.000000000000121 76.0
HFD3_k127_2565815_2 D-gluconate metabolic process K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 383.0
HFD3_k127_2565815_3 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 353.0
HFD3_k127_2565815_4 Major facilitator Superfamily K08223 - - 0.0000000000000000000000000000000000000000000000000000006877 209.0
HFD3_k127_2565815_5 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000001581 180.0
HFD3_k127_2565815_6 Rieske-like [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000003431 168.0
HFD3_k127_2565815_7 galactose-6-phosphate isomerase activity K01808 - 5.3.1.6 0.00000000000000000000000000000000000001096 147.0
HFD3_k127_2565815_8 6-phosphogluconolactonase K01057 - 3.1.1.31 0.000000000000000000000000000009422 130.0
HFD3_k127_2565815_9 Glucose-6-phosphate dehydrogenase subunit - - - 0.00000000000000000000001701 118.0
HFD3_k127_2586638_0 Asparagine synthase K01953 - 6.3.5.4 1.35e-226 718.0
HFD3_k127_2586638_1 NmrA-like family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 373.0
HFD3_k127_2586638_2 transferase activity, transferring glycosyl groups K09691 - - 0.0000000000000000000000000000000000000000000000000000000000000000383 241.0
HFD3_k127_2586638_3 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000003123 218.0
HFD3_k127_2590564_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 3.416e-225 735.0
HFD3_k127_2590564_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 8.152e-222 712.0
HFD3_k127_2590564_10 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000002472 175.0
HFD3_k127_2590564_11 Major Facilitator Superfamily - - - 0.00000000000000000000000000000001374 138.0
HFD3_k127_2590564_12 Glucitol operon activator protein (GutM) K02466 - - 0.0000005232 61.0
HFD3_k127_2590564_2 PFAM thiamine pyrophosphate enzyme-like TPP-binding thiamine pyrophosphate K01576,K01652 - 2.2.1.6,4.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004445 630.0
HFD3_k127_2590564_3 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007189 382.0
HFD3_k127_2590564_4 protein-phosphocysteine-sugar phosphotransferase activity K02782,K02783 - 2.7.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000372 253.0
HFD3_k127_2590564_5 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005717 253.0
HFD3_k127_2590564_6 PTS system glucitol sorbitol-specific K02783 GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0051179,GO:0051234,GO:0071702 - 0.0000000000000000000000000000000000000000000000000000000000000000000003786 242.0
HFD3_k127_2590564_7 2 iron, 2 sulfur cluster binding K03518,K07302 - 1.2.5.3,1.3.99.16 0.0000000000000000000000000000000000000000000000000003545 196.0
HFD3_k127_2590564_8 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000002335 189.0
HFD3_k127_2590564_9 Ion channel - - - 0.0000000000000000000000000000000000000000000002148 193.0
HFD3_k127_2597636_0 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 560.0
HFD3_k127_2597636_1 - - - - 0.0000000000000000000000000000000000000000000002432 192.0
HFD3_k127_2605766_0 Molybdopterin-binding domain of aldehyde dehydrogenase - - - 3.237e-225 730.0
HFD3_k127_2605766_1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006348 323.0
HFD3_k127_2605766_2 PFAM Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009573 251.0
HFD3_k127_2605766_3 Copper resistance protein CopC K14166 - - 0.00000000000000000000000000003741 135.0
HFD3_k127_2605766_4 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.000000000000000000000000000048 128.0
HFD3_k127_2605766_5 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K06034 GO:0003674,GO:0003824,GO:0006082,GO:0006732,GO:0006790,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019295,GO:0019296,GO:0044237,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0050545,GO:0051186,GO:0051188,GO:0071704,GO:1901576 4.1.1.79 0.000000000000000007418 89.0
HFD3_k127_2605766_6 - - - - 0.00000000000000002302 92.0
HFD3_k127_2605766_7 membrane transporter protein - - - 0.000074 53.0
HFD3_k127_271408_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 433.0
HFD3_k127_271408_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009591 398.0
HFD3_k127_271408_10 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000001322 214.0
HFD3_k127_271408_11 cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000004095 205.0
HFD3_k127_271408_12 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000001986 201.0
HFD3_k127_271408_13 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000002732 137.0
HFD3_k127_271408_14 phosphoglycerate mutase K02226,K22316 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.73 0.0000000000000000000000000005893 121.0
HFD3_k127_271408_15 Protein of unknown function (DUF1290) - - - 0.00000000000000000000000001154 112.0
HFD3_k127_271408_16 IstB-like ATP binding protein - - - 0.00000000000000000000001876 108.0
HFD3_k127_271408_17 YGGT family K02221 - - 0.0000000000002782 72.0
HFD3_k127_271408_18 Belongs to the UPF0235 family K09131 - - 0.00000000001573 76.0
HFD3_k127_271408_19 peptidase - - - 0.0000007481 61.0
HFD3_k127_271408_2 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 353.0
HFD3_k127_271408_20 POTRA domain, FtsQ-type K03589 - - 0.00006121 55.0
HFD3_k127_271408_21 META domain - - - 0.0002451 52.0
HFD3_k127_271408_22 succinate dehydrogenase K00239 GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363 1.3.5.1,1.3.5.4 0.00025 45.0
HFD3_k127_271408_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 350.0
HFD3_k127_271408_4 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 340.0
HFD3_k127_271408_5 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005836 312.0
HFD3_k127_271408_6 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005114 302.0
HFD3_k127_271408_7 Penicillin-binding Protein dimerisation domain K03587,K08384 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000002011 261.0
HFD3_k127_271408_8 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000216 243.0
HFD3_k127_271408_9 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000003257 255.0
HFD3_k127_2720071_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 4.659e-230 720.0
HFD3_k127_2720071_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 8.971e-216 686.0
HFD3_k127_2720071_10 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008569 307.0
HFD3_k127_2720071_11 belongs to the sigma-70 factor family K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 286.0
HFD3_k127_2720071_12 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000007434 250.0
HFD3_k127_2720071_13 Prephenate dehydratase K04518,K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000001391 235.0
HFD3_k127_2720071_14 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000003403 230.0
HFD3_k127_2720071_15 ACT domain K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000002124 182.0
HFD3_k127_2720071_16 Colicin V production protein - - - 0.0000000000000000000000000000000000000001254 166.0
HFD3_k127_2720071_17 Domain of unknown function (DUF4332) - - - 0.000000000000000000000000000000001014 136.0
HFD3_k127_2720071_18 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000003846 121.0
HFD3_k127_2720071_19 cyclic nucleotide binding K10914 - - 0.000000000000000000000000001809 120.0
HFD3_k127_2720071_2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 624.0
HFD3_k127_2720071_20 cyclic nucleotide binding K10914 - - 0.000000000000001192 84.0
HFD3_k127_2720071_21 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0000000006746 67.0
HFD3_k127_2720071_3 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 597.0
HFD3_k127_2720071_4 Bacterial protein of unknown function (DUF853) K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004679 523.0
HFD3_k127_2720071_5 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005599 500.0
HFD3_k127_2720071_6 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005244 502.0
HFD3_k127_2720071_7 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 441.0
HFD3_k127_2720071_8 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008735 401.0
HFD3_k127_2720071_9 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 335.0
HFD3_k127_2791338_0 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 576.0
HFD3_k127_2791338_1 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 516.0
HFD3_k127_2791338_2 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 316.0
HFD3_k127_2791338_3 Amidohydrolase family K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000003408 274.0
HFD3_k127_2791338_4 Protein of unknown function DUF45 K07043 - - 0.000000000000000000000000000000005748 138.0
HFD3_k127_2791338_5 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000003838 101.0
HFD3_k127_283786_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 3.596e-219 712.0
HFD3_k127_283786_1 GTP-binding protein TypA K06207 - - 2.68e-216 689.0
HFD3_k127_283786_10 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001087 295.0
HFD3_k127_283786_11 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003991 286.0
HFD3_k127_283786_12 Tyrosine recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003073 268.0
HFD3_k127_283786_13 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001881 255.0
HFD3_k127_283786_14 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002157 263.0
HFD3_k127_283786_15 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000001913 240.0
HFD3_k127_283786_16 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000004144 231.0
HFD3_k127_283786_17 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000003663 224.0
HFD3_k127_283786_18 Creatinase/Prolidase N-terminal domain K01262,K01271,K08326 GO:0003674,GO:0003824,GO:0004177,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000001371 226.0
HFD3_k127_283786_19 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000257 208.0
HFD3_k127_283786_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.088e-196 633.0
HFD3_k127_283786_20 RNA pseudouridylate synthase K06178,K06183 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.22 0.00000000000000000000000000000000000000000000003977 190.0
HFD3_k127_283786_21 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000001577 185.0
HFD3_k127_283786_22 - - - - 0.0000000000000000000000000000000000000000001289 174.0
HFD3_k127_283786_23 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000001137 174.0
HFD3_k127_283786_24 Peptidase M50 - - - 0.00000000000000000000000000000000000000002201 161.0
HFD3_k127_283786_25 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000004315 156.0
HFD3_k127_283786_26 WD40 domain protein beta Propeller K03641 - - 0.0000000000000000000000000000001554 143.0
HFD3_k127_283786_27 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000001133 115.0
HFD3_k127_283786_28 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.000000000000000000000573 101.0
HFD3_k127_283786_29 PFAM membrane-flanked domain - - - 0.000000000000000000003675 107.0
HFD3_k127_283786_3 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008246 439.0
HFD3_k127_283786_30 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000006104 103.0
HFD3_k127_283786_31 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000002948 85.0
HFD3_k127_283786_32 transcriptional regulator - - - 0.000000000003781 76.0
HFD3_k127_283786_33 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000001987 65.0
HFD3_k127_283786_34 mRNA catabolic process - - - 0.000000003249 68.0
HFD3_k127_283786_35 MobA-like NTP transferase domain K07141,K19190 - 1.1.1.328,2.7.7.76 0.0000501 55.0
HFD3_k127_283786_36 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family - - - 0.00009764 46.0
HFD3_k127_283786_4 cell division - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 373.0
HFD3_k127_283786_5 Aminotransferase class-V K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004445 366.0
HFD3_k127_283786_6 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 361.0
HFD3_k127_283786_7 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 320.0
HFD3_k127_283786_8 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 303.0
HFD3_k127_283786_9 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002863 290.0
HFD3_k127_2856715_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 3.695e-264 827.0
HFD3_k127_2856715_1 Heat shock 70 kDa protein K04043 - - 1.91e-210 665.0
HFD3_k127_2856715_10 CAAX protease self-immunity K07052 - - 0.00004345 54.0
HFD3_k127_2856715_11 rRNA binding K02968 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0004045 50.0
HFD3_k127_2856715_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 559.0
HFD3_k127_2856715_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004233 493.0
HFD3_k127_2856715_4 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 456.0
HFD3_k127_2856715_5 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005161 256.0
HFD3_k127_2856715_6 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002524 257.0
HFD3_k127_2856715_7 DinB family - - - 0.00000000000000000000000000000000000000006712 159.0
HFD3_k127_2856715_8 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000177 151.0
HFD3_k127_2856715_9 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0017076,GO:0030234,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071496,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000000000000001025 125.0
HFD3_k127_2866953_0 Mycobacterial 4 TMS phage holin, superfamily IV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 443.0
HFD3_k127_2866953_1 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000004412 222.0
HFD3_k127_2866953_2 SnoaL-like polyketide cyclase K15945 - - 0.00000000000000000000000000000000000000000000000000003518 195.0
HFD3_k127_2888558_0 Berberine and berberine like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 484.0
HFD3_k127_2888558_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001607 286.0
HFD3_k127_2888558_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000257 223.0
HFD3_k127_2888558_3 Helix-turn-helix type 11 domain protein K13572 - - 0.000000009546 57.0
HFD3_k127_2972240_0 Glycogen debranching enzyme - - - 1.652e-194 630.0
HFD3_k127_2972240_1 Zn-dependent metallo-hydrolase RNA specificity domain K07577,K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008189 486.0
HFD3_k127_2972240_10 Binding-protein-dependent transport system inner membrane component K05846 - - 0.00000000000000000000000000000000000000000000000005549 189.0
HFD3_k127_2972240_11 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000004057 160.0
HFD3_k127_2972240_12 Glycine betaine K05845 - - 0.000000000000000000000000000000007362 141.0
HFD3_k127_2972240_13 PFAM regulatory protein LuxR - - - 0.0000000000000000000000000000001056 134.0
HFD3_k127_2972240_14 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000003498 124.0
HFD3_k127_2972240_2 )-transporter K05847 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007452 385.0
HFD3_k127_2972240_3 PFAM oxidoreductase, molybdopterin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 286.0
HFD3_k127_2972240_4 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 288.0
HFD3_k127_2972240_5 Cys/Met metabolism PLP-dependent enzyme K11325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008007 283.0
HFD3_k127_2972240_6 Belongs to the N(4) N(6)-methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001204 264.0
HFD3_k127_2972240_7 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000000000000000000000000000000003818 218.0
HFD3_k127_2972240_8 Binding-protein-dependent transport system inner membrane component K05846 - - 0.0000000000000000000000000000000000000000000000000003293 193.0
HFD3_k127_2972240_9 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000009825 191.0
HFD3_k127_299041_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 6.758e-255 794.0
HFD3_k127_299041_1 phosphoenolpyruvate carboxykinase (ATP) activity K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 627.0
HFD3_k127_299041_10 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000002992 87.0
HFD3_k127_299041_11 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000017 81.0
HFD3_k127_299041_12 STAS domain K06378 - - 0.00000162 55.0
HFD3_k127_299041_2 Cysteine synthase K01697,K01738,K12339 - 2.5.1.47,4.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007896 504.0
HFD3_k127_299041_3 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005683 436.0
HFD3_k127_299041_4 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008109 393.0
HFD3_k127_299041_5 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 348.0
HFD3_k127_299041_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000001397 194.0
HFD3_k127_299041_7 Dihydropyrimidinase K01464 - 3.5.2.2 0.000000000000000000000000000000000000000000000005917 174.0
HFD3_k127_299041_8 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.000000000000000000000000000000000000001507 160.0
HFD3_k127_299041_9 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K04757 - 2.7.11.1 0.000000000000000264 85.0
HFD3_k127_308952_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000234 275.0
HFD3_k127_308952_1 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.000000000000000003588 94.0
HFD3_k127_3091259_0 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006123 443.0
HFD3_k127_3091259_1 Ribbon-helix-helix protein, copG family - - - 0.00002283 49.0
HFD3_k127_3100639_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007382 403.0
HFD3_k127_3100639_1 Sodium/hydrogen exchanger family K03316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009072 351.0
HFD3_k127_3100639_2 translation initiation factor activity K06996 - - 0.00000000000000003658 96.0
HFD3_k127_3100639_3 Ppx GppA phosphatase family protein K01524 - 3.6.1.11,3.6.1.40 0.0000000001369 74.0
HFD3_k127_3100639_4 Calcineurin-like phosphoesterase superfamily domain - - - 0.0008535 47.0
HFD3_k127_3128724_0 Poly(3-hydroxybutyrate) depolymerase K03932 - - 0.00000000000000000000000000000000000000009535 165.0
HFD3_k127_3128724_1 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000949 122.0
HFD3_k127_3128724_2 - - - - 0.0003618 51.0
HFD3_k127_3139303_0 Nucleotidyl transferase K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 473.0
HFD3_k127_3139303_1 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 463.0
HFD3_k127_3139303_10 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000001439 214.0
HFD3_k127_3139303_11 PFAM Haloacid dehalogenase domain protein hydrolase - - - 0.00000000000000000000000000000000000000000000009153 179.0
HFD3_k127_3139303_12 BioY family K03523 - - 0.0000000000000000000000000000000000000000000001274 175.0
HFD3_k127_3139303_13 pfam nudix K01515 - 3.6.1.13 0.00000000000000000000000000000000000000002137 165.0
HFD3_k127_3139303_14 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.000000000000000000000000000000000000006954 160.0
HFD3_k127_3139303_15 - - - - 0.0000000000000000000000000000000000005325 145.0
HFD3_k127_3139303_16 aminopeptidase N - - - 0.000000000000000000000000000000000002313 159.0
HFD3_k127_3139303_17 SMART Peptidoglycan-binding LysM - - - 0.0000000000000000000000000000000003163 148.0
HFD3_k127_3139303_18 dienelactone hydrolase - - - 0.0000000000000000000000000000003025 132.0
HFD3_k127_3139303_19 aldehyde oxidase and xanthine dehydrogenase a b hammerhead - - - 0.000000000000000000000000000002061 133.0
HFD3_k127_3139303_2 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 404.0
HFD3_k127_3139303_20 PFAM Cysteine-rich secretory protein family - - - 0.0000000000000000000002867 107.0
HFD3_k127_3139303_21 Sigma-70, region 4 - - - 0.00000000000000002676 90.0
HFD3_k127_3139303_22 Tetratricopeptide repeat - - - 0.0000000009446 68.0
HFD3_k127_3139303_23 Type IV leader peptidase family K02654 - 3.4.23.43 0.00000003757 65.0
HFD3_k127_3139303_3 N-acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 392.0
HFD3_k127_3139303_4 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 345.0
HFD3_k127_3139303_5 Amidohydrolase family K01487 GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006144,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008892,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0016814,GO:0018756,GO:0019239,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0046098,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072521,GO:1901360,GO:1901564 3.5.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 313.0
HFD3_k127_3139303_6 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004043 255.0
HFD3_k127_3139303_7 PFAM Haloacid dehalogenase domain protein hydrolase K01560,K07025 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000009512 249.0
HFD3_k127_3139303_8 Adenosine/AMP deaminase K01488 - 3.5.4.4 0.00000000000000000000000000000000000000000000000000000000000007955 226.0
HFD3_k127_3139303_9 Sporulation and spore germination - - - 0.0000000000000000000000000000000000000000000000000000000006113 218.0
HFD3_k127_3147395_0 GMC oxidoreductase K00108 - 1.1.99.1 2.219e-279 867.0
HFD3_k127_3147395_1 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006472 297.0
HFD3_k127_3147395_2 PFAM Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000004718 225.0
HFD3_k127_3147395_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000008109 176.0
HFD3_k127_3147395_4 PFAM Peptidase M11 gametolysin - - - 0.000000000000000000000000000000000000001475 168.0
HFD3_k127_3147395_5 belongs to the glycosyl hydrolase 13 family K01176,K01208 GO:0005575,GO:0005576 3.2.1.1,3.2.1.133,3.2.1.135,3.2.1.54 0.000000000000000000000000000000003363 148.0
HFD3_k127_3147395_6 Belongs to the UPF0312 family - - - 0.00000000000000000002814 105.0
HFD3_k127_3326503_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0040007,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 3.088e-195 632.0
HFD3_k127_3326503_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002025 264.0
HFD3_k127_3326503_2 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000915 173.0
HFD3_k127_3326503_3 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) K02351,K07245 - - 0.000000000000000000000000000000000000000002283 168.0
HFD3_k127_3326503_4 cytochrome c oxidase, subunit III K02276,K02299 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.9.3.1 0.0000000000000000000000000000000000003226 162.0
HFD3_k127_3326503_5 Cytochrome C oxidase subunit II, periplasmic domain K02275 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 0.0000000000000000000000000000000003498 150.0
HFD3_k127_3326503_6 periplasmic protein thiol disulfide oxidoreductases, DsbE subfamily K02199 - - 0.000000000000000000000000007881 117.0
HFD3_k127_3326503_7 PFAM blue (type 1) copper domain protein - - - 0.000001169 60.0
HFD3_k127_3331162_0 Carbohydrate phosphorylase K00688,K00691 - 2.4.1.1,2.4.1.8 2.157e-198 641.0
HFD3_k127_3331162_1 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 414.0
HFD3_k127_3331162_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006405 331.0
HFD3_k127_3331162_3 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000075 227.0
HFD3_k127_3331162_4 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000004482 117.0
HFD3_k127_3331162_5 PFAM Cupin 2, conserved barrel - - - 0.00000000000000000000006071 115.0
HFD3_k127_3331162_6 PFAM amino acid-binding ACT domain protein - - - 0.0000000002 70.0
HFD3_k127_3331274_0 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000001289 158.0
HFD3_k127_3331274_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000006549 130.0
HFD3_k127_3331274_2 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000112 119.0
HFD3_k127_3331274_3 Helix-turn-helix domain K07729 - - 0.0000000000000000009777 87.0
HFD3_k127_3331274_4 protein phosphatase 2C domain protein - - - 0.00000015 58.0
HFD3_k127_3331274_5 Predicted membrane protein (DUF2178) - - - 0.0000008887 57.0
HFD3_k127_3342606_0 Type II/IV secretion system protein K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009861 492.0
HFD3_k127_3342606_1 PFAM response regulator receiver K02282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007351 346.0
HFD3_k127_3342606_2 response regulator - - - 0.00000000000000000000000004133 108.0
HFD3_k127_3342606_3 Histidine kinase K07777 - 2.7.13.3 0.0000000000000000000000000508 123.0
HFD3_k127_3342606_4 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.00000003359 64.0
HFD3_k127_3342606_5 Flp/Fap pilin component K02651 - - 0.00001369 49.0
HFD3_k127_3342606_6 Flp/Fap pilin component K02651 - - 0.00004721 48.0
HFD3_k127_3449516_0 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 1.83e-233 765.0
HFD3_k127_3449516_1 Putative glutamine amidotransferase K07114 - - 2.123e-202 664.0
HFD3_k127_3449516_10 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 346.0
HFD3_k127_3449516_11 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009156,GO:0009161,GO:0009163,GO:0009164,GO:0009165,GO:0009167,GO:0009168,GO:0009987,GO:0015949,GO:0015950,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0032261,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0043173,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009693 342.0
HFD3_k127_3449516_12 ATPase activity K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 312.0
HFD3_k127_3449516_13 COGs COG3367 conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002089 295.0
HFD3_k127_3449516_14 Belongs to the GMC oxidoreductase family K00108 - 1.1.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001424 290.0
HFD3_k127_3449516_15 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001781 264.0
HFD3_k127_3449516_16 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004124 268.0
HFD3_k127_3449516_17 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001452 265.0
HFD3_k127_3449516_18 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000007634 239.0
HFD3_k127_3449516_19 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 - 5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000005044 235.0
HFD3_k127_3449516_2 amine dehydrogenase activity - - - 1.4e-200 645.0
HFD3_k127_3449516_20 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000002056 242.0
HFD3_k127_3449516_22 PFAM AMP-dependent synthetase and ligase - - - 0.00000000000000000000000000000000000000000000000000005643 213.0
HFD3_k127_3449516_23 N-4 methylation of cytosine K00590 - 2.1.1.113 0.0000000000000000000000000000000000000000000000000002602 203.0
HFD3_k127_3449516_24 domain, Protein - - - 0.000000000000000000000000000000000000000000000003512 190.0
HFD3_k127_3449516_25 Transcriptional regulator - - - 0.000000000000000000000000000003109 134.0
HFD3_k127_3449516_26 ABC-2 family transporter protein - - - 0.00000000000000000000000000006021 132.0
HFD3_k127_3449516_27 LysM domain - - - 0.00000000000000000000000000961 129.0
HFD3_k127_3449516_28 geranylgeranyl reductase K21401 - 1.3.99.38 0.0000000000000000000000001231 119.0
HFD3_k127_3449516_29 Alpha beta hydrolase - - - 0.00000000000000000000005422 109.0
HFD3_k127_3449516_3 COG0044 Dihydroorotase and related cyclic amidohydrolases K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007587 595.0
HFD3_k127_3449516_30 Multicopper oxidase K00368 - 1.7.2.1 0.000000000001084 80.0
HFD3_k127_3449516_31 - - - - 0.0000000114 63.0
HFD3_k127_3449516_32 Two component regulator propeller - - - 0.0000004876 61.0
HFD3_k127_3449516_34 homolog of phage Mu protein gp47 - - - 0.000006384 57.0
HFD3_k127_3449516_4 PFAM Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004066 440.0
HFD3_k127_3449516_5 PFAM Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007284 394.0
HFD3_k127_3449516_6 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008237 387.0
HFD3_k127_3449516_7 acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 384.0
HFD3_k127_3449516_8 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 377.0
HFD3_k127_3449516_9 Aerotolerance regulator N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 378.0
HFD3_k127_34705_0 Aminotransferase class-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 384.0
HFD3_k127_34705_1 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 331.0
HFD3_k127_34705_2 Mechanosensitive ion channel K22044 - - 0.0000000000000000000000000000000000000000004121 164.0
HFD3_k127_3496784_0 decarboxylase K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000609 517.0
HFD3_k127_3496784_1 Belongs to the dCTP deaminase family K01494 GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0019239,GO:0033973,GO:0047429 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000002979 252.0
HFD3_k127_3496784_2 Acyl-CoA dehydrogenase, C-terminal domain K00248,K00249 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.3.8.1,1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000001371 241.0
HFD3_k127_3496784_3 electron transfer flavoprotein, alpha subunit K03522 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000002259 208.0
HFD3_k127_3496784_4 Electron transfer flavoprotein domain K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.000000000000000000000000000000000000000000000000002074 192.0
HFD3_k127_3496784_5 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000004534 159.0
HFD3_k127_3496784_6 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000002435 158.0
HFD3_k127_3496784_7 endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000003998 131.0
HFD3_k127_3496784_8 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000581 117.0
HFD3_k127_3496784_9 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000002609 111.0
HFD3_k127_3506426_0 Domain of unknown function (DUF4162) K01990 - - 0.0000000000000000000000000000000000000000000000000002612 193.0
HFD3_k127_3506426_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000001532 165.0
HFD3_k127_3506426_2 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000003169 59.0
HFD3_k127_3506426_3 sequence-specific DNA binding - - - 0.0002679 52.0
HFD3_k127_3541088_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 7.867e-238 746.0
HFD3_k127_3541088_1 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.0000000000000000000000000000000000000000000000000000000000000000000000000008117 264.0
HFD3_k127_3541088_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00122,K00335 - 1.17.1.9,1.6.5.3 0.000000000000000000000000000000000001501 141.0
HFD3_k127_3541088_3 Molybdopterin oxidoreductase K00123 - 1.17.1.9 0.000000000000000000000000003245 114.0
HFD3_k127_3541088_4 - - - - 0.00000000000188 75.0
HFD3_k127_3541088_5 Cupredoxin-like domain - - - 0.0008163 48.0
HFD3_k127_3547016_0 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009264 300.0
HFD3_k127_3547016_1 Histidine kinase - - - 0.000000000000000000002331 108.0
HFD3_k127_3547016_2 Uncharacterized conserved protein (DUF2277) - - - 0.00000000001066 76.0
HFD3_k127_360019_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.372e-215 684.0
HFD3_k127_360019_1 succinate dehydrogenase, flavoprotein subunit K00239 GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363 1.3.5.1,1.3.5.4 1.177e-200 650.0
HFD3_k127_360019_10 Biotin-requiring enzyme - - - 0.00000000002409 76.0
HFD3_k127_360019_2 PFAM isocitrate isopropylmalate dehydrogenase K00030,K07246 - 1.1.1.41,1.1.1.83,1.1.1.93,4.1.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000499 486.0
HFD3_k127_360019_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 372.0
HFD3_k127_360019_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 376.0
HFD3_k127_360019_5 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001616 286.0
HFD3_k127_360019_6 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000002069 245.0
HFD3_k127_360019_7 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000001428 150.0
HFD3_k127_360019_8 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.0000000000000000000000000000002694 139.0
HFD3_k127_360019_9 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000002172 127.0
HFD3_k127_3628139_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005586 302.0
HFD3_k127_3628139_1 Two component transcriptional regulator, winged helix family K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001458 282.0
HFD3_k127_3628139_2 Histidine kinase K07642 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000004606 222.0
HFD3_k127_3628139_3 Inhibitor of apoptosis-promoting Bax1 K06890,K19416 - - 0.00000000000000000000000000000000000000000468 168.0
HFD3_k127_3628139_4 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000001069 133.0
HFD3_k127_3628139_5 Pfam:DUF59 - - - 0.0000000000001293 76.0
HFD3_k127_3654564_0 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004799 325.0
HFD3_k127_3654564_1 Capsule synthesis protein, CapA K07282 - - 0.0000000000000000000000000000000000000000000000000000000000000000001109 252.0
HFD3_k127_3654564_2 CoA-transferase family III K18702 - 2.8.3.19 0.00000000000000000000000000000000000000000000000000000000000001309 224.0
HFD3_k127_3654564_3 N-acetylglucosaminylinositol deacetylase activity K18455 - 3.5.1.115 0.00000000000000000000000000000000000000000000000000000000000009375 228.0
HFD3_k127_3654564_4 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000009551 220.0
HFD3_k127_376744_0 Aminotransferase class-V - - - 7.579e-244 766.0
HFD3_k127_376744_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00596,K00823 - 2.6.1.19,4.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 528.0
HFD3_k127_376744_10 histidine kinase dimerisation and phosphoacceptor region K03406,K07673,K07675 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001022 291.0
HFD3_k127_376744_11 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001087 285.0
HFD3_k127_376744_12 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000003376 274.0
HFD3_k127_376744_13 Two component transcriptional regulator, LuxR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000791 244.0
HFD3_k127_376744_14 PASTA domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000014 177.0
HFD3_k127_376744_15 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000001033 170.0
HFD3_k127_376744_16 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.000000000000000000000000000000000000008367 147.0
HFD3_k127_376744_17 AAA ATPase domain - - - 0.0000000000000000000000000009912 132.0
HFD3_k127_376744_18 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000273 85.0
HFD3_k127_376744_19 Universal stress protein family - GO:0000166,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016208,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044464,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000001613 80.0
HFD3_k127_376744_2 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000052 527.0
HFD3_k127_376744_20 spore germination K03605 - - 0.000002741 60.0
HFD3_k127_376744_3 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 507.0
HFD3_k127_376744_4 PFAM Acetyl-CoA hydrolase transferase K01067 - 3.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005943 461.0
HFD3_k127_376744_5 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 450.0
HFD3_k127_376744_6 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 394.0
HFD3_k127_376744_7 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006922 340.0
HFD3_k127_376744_8 Sodium/calcium exchanger protein K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 334.0
HFD3_k127_376744_9 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005641 334.0
HFD3_k127_3921437_0 MMPL family K06994 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008476 516.0
HFD3_k127_3921437_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006048 430.0
HFD3_k127_3921437_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K03851,K15372 - 2.6.1.55,2.6.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008726 354.0
HFD3_k127_3921437_3 - - - - 0.0000000000000000000000000000000000000000000018 171.0
HFD3_k127_3924567_0 VIT family - - - 0.0000000000000000000000000000002523 127.0
HFD3_k127_3924567_1 Zinc metalloprotease (Elastase) K01183 - 3.2.1.14 0.000000000000000000000000000344 128.0
HFD3_k127_3924567_2 cheY-homologous receiver domain - - - 0.00000000000000000000004062 107.0
HFD3_k127_3924567_3 VIT family - - - 0.0000000000000006732 80.0
HFD3_k127_3936358_0 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000001026 198.0
HFD3_k127_3936358_1 Pfam:DUF2029 - - - 0.00000000000000000000000000000000000007338 151.0
HFD3_k127_3936358_2 Protein involved in cellulose biosynthesis - - - 0.0000000000000000000000007932 115.0
HFD3_k127_3942391_0 IMS family HHH motif K02346 GO:0008150,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0050896 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 367.0
HFD3_k127_3942391_1 Belongs to the formate--tetrahydrofolate ligase family K01938 GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006148 327.0
HFD3_k127_3942391_10 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000006561 83.0
HFD3_k127_3942391_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000001361 263.0
HFD3_k127_3942391_3 chaperone-mediated protein folding - - - 0.000000000000000000000000000000000000000000000000000002344 219.0
HFD3_k127_3942391_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000006976 155.0
HFD3_k127_3942391_5 membrane - - - 0.00000000000000000000000000000000001965 150.0
HFD3_k127_3942391_6 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000001725 145.0
HFD3_k127_3942391_7 NHL repeat containing protein - - - 0.0000000000000000000000000000003884 143.0
HFD3_k127_3942391_8 PFAM Formiminotransferase-cyclodeaminase - - - 0.00000000000000000000000007056 116.0
HFD3_k127_3942391_9 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000006587 103.0
HFD3_k127_3977238_0 PFAM alpha amylase, catalytic K01208 - 3.2.1.133,3.2.1.135,3.2.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 534.0
HFD3_k127_3977238_1 Alcohol dehydrogenase GroES-like domain K00060 - 1.1.1.103 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 494.0
HFD3_k127_3977238_2 Cys/Met metabolism PLP-dependent enzyme K00639 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 473.0
HFD3_k127_3977238_3 periplasmic binding protein LacI transcriptional regulator K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000008016 264.0
HFD3_k127_3977238_4 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000002599 226.0
HFD3_k127_3977238_5 TIGRFAM histidinol phosphate phosphatase HisJ family K04486 GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15 0.00000000000000000000000000000000000005386 164.0
HFD3_k127_3977238_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000005856 136.0
HFD3_k127_3977238_7 Protein of unknown function (DUF3105) - - - 0.0000000000000001006 91.0
HFD3_k127_3977238_8 PFAM methyltransferase - - - 0.0005959 50.0
HFD3_k127_3977238_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07032 - - 0.0007843 43.0
HFD3_k127_4050313_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005947 434.0
HFD3_k127_4050313_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001016 231.0
HFD3_k127_4050313_2 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000001222 167.0
HFD3_k127_4050313_3 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000001301 109.0
HFD3_k127_4050313_4 Sulfurtransferase TusA - - - 0.0000000000000000000001394 99.0
HFD3_k127_4050313_5 Belongs to the sulfur carrier protein TusA family K04085 - - 0.0000000000000000003501 89.0
HFD3_k127_4050313_6 Transcriptional regulator - - - 0.0000000000000008657 86.0
HFD3_k127_4072751_0 COG0475 Kef-type K transport systems, membrane components K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009515 432.0
HFD3_k127_4072751_1 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001631 280.0
HFD3_k127_4072751_2 L-carnitine dehydratase bile acid-inducible protein F K18702 - 2.8.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000009178 254.0
HFD3_k127_4072751_3 Domain of unknown function (DUF4162) K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002745 256.0
HFD3_k127_4072751_4 Multicopper oxidase K00368 - 1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000005279 230.0
HFD3_k127_4072751_5 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000005064 141.0
HFD3_k127_4072751_6 DSBA-like thioredoxin domain - - - 0.000000000000000000000001704 113.0
HFD3_k127_4072751_7 ABC-2 family transporter protein K01992 - - 0.0000000000000000000008168 108.0
HFD3_k127_4072751_8 PFAM Vitamin K epoxide reductase - - - 0.0000000000001242 78.0
HFD3_k127_4072751_9 Negative regulatory protein YxlE - - - 0.000000000008134 70.0
HFD3_k127_4085804_0 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000007556 277.0
HFD3_k127_4087603_0 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 3.112e-227 728.0
HFD3_k127_4087603_1 R3H domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 557.0
HFD3_k127_4087603_10 Carbon-nitrogen hydrolase K11206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001688 294.0
HFD3_k127_4087603_11 Protein of unknown function (DUF1211) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006753 256.0
HFD3_k127_4087603_12 Belongs to the glycerate kinase type-1 family K00865 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000004732 276.0
HFD3_k127_4087603_13 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002235 266.0
HFD3_k127_4087603_14 Enoyl-CoA hydratase/isomerase K13766,K13779 - 4.2.1.18,4.2.1.57 0.000000000000000000000000000000000000000000000000000000000000000007469 238.0
HFD3_k127_4087603_15 Belongs to the UPF0173 family - - - 0.0000000000000000000000000000000000000000000000000000000000000001425 229.0
HFD3_k127_4087603_16 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000001787 231.0
HFD3_k127_4087603_17 SMART HNH nuclease - - - 0.00000000000000000000000000000000000000000000000000000000000002664 218.0
HFD3_k127_4087603_18 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000009719 199.0
HFD3_k127_4087603_19 MOSC domain containing protein K07140 - - 0.000000000000000000000000000000000000000000000002498 189.0
HFD3_k127_4087603_2 Amidohydrolase K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 503.0
HFD3_k127_4087603_20 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000001036 190.0
HFD3_k127_4087603_21 Response regulator receiver - - - 0.00000000000000000000000000000000000000000002507 173.0
HFD3_k127_4087603_22 Histidine kinase A domain protein - - - 0.000000000000000000000000000000002115 147.0
HFD3_k127_4087603_23 MOSC domain - - - 0.0000000000000000000000000000001259 129.0
HFD3_k127_4087603_24 Glyoxalase-like domain - - - 0.0000000000000000000000002259 118.0
HFD3_k127_4087603_25 Belongs to the GbsR family - - - 0.0000000000000828 81.0
HFD3_k127_4087603_26 - - - - 0.00000003262 63.0
HFD3_k127_4087603_27 dna ligase - - - 0.00000007931 62.0
HFD3_k127_4087603_28 - - - - 0.00004076 56.0
HFD3_k127_4087603_3 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000355 458.0
HFD3_k127_4087603_4 Biotin carboxylase C-terminal domain K01968 - 6.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005733 478.0
HFD3_k127_4087603_5 transferase activity, transferring glycosyl groups K09118,K13693,K21349 - 2.4.1.266,2.4.1.268 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008837 455.0
HFD3_k127_4087603_6 Glycosyl transferase, family 2 K21349 - 2.4.1.268 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 379.0
HFD3_k127_4087603_7 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 330.0
HFD3_k127_4087603_8 Probable RNA and SrmB- binding site of polymerase A K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 332.0
HFD3_k127_4087603_9 HMGL-like K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 315.0
HFD3_k127_4123371_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004368 612.0
HFD3_k127_4123371_1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.0000000000000000000001962 104.0
HFD3_k127_4177024_0 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 503.0
HFD3_k127_4177024_1 L-seryl-tRNA selenium transferase K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005317 339.0
HFD3_k127_4177024_10 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000001007 76.0
HFD3_k127_4177024_2 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 GO:0000287,GO:0003674,GO:0003824,GO:0004016,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006171,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009187,GO:0009190,GO:0009259,GO:0009260,GO:0009975,GO:0009987,GO:0016020,GO:0016829,GO:0016849,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0023052,GO:0030145,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046058,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052652,GO:0055086,GO:0065007,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009301 332.0
HFD3_k127_4177024_3 Elongation factor SelB, winged helix K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004848 293.0
HFD3_k127_4177024_4 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009994 285.0
HFD3_k127_4177024_5 PFAM Adenosine AMP deaminase K01488,K18286 GO:0000034,GO:0003674,GO:0003824,GO:0006139,GO:0006144,GO:0006145,GO:0006146,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0046083,GO:0046100,GO:0046101,GO:0046112,GO:0046113,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.4.4,3.5.4.40 0.00000000000000000000000000000000000000000000000000009068 199.0
HFD3_k127_4177024_6 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000004659 187.0
HFD3_k127_4177024_7 Calcineurin-like phosphoesterase K03547 - - 0.0000000000000000000000000000144 132.0
HFD3_k127_4177024_8 Probable zinc-ribbon domain - - - 0.000000000000000000000000002813 117.0
HFD3_k127_4177024_9 AAA domain - - - 0.000000000000000000000001281 121.0
HFD3_k127_4190233_0 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 378.0
HFD3_k127_4190233_1 Glycosyltransferase Family 4 K12995 - 2.4.1.348 0.0000005074 56.0
HFD3_k127_4190233_2 - - - - 0.00000263 54.0
HFD3_k127_4263800_0 DNA primase, small subunit K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 607.0
HFD3_k127_4263800_1 ATP dependent DNA ligase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 567.0
HFD3_k127_4263800_10 response regulator receiver K07658,K07668 - - 0.0000000000000000000000000000000000000000000000000000000000000008305 227.0
HFD3_k127_4263800_11 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000005139 223.0
HFD3_k127_4263800_12 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000001092 225.0
HFD3_k127_4263800_13 PDZ domain (Also known as DHR or GLGF) - - - 0.0000000000000000000000000000000000000000000000000000008568 210.0
HFD3_k127_4263800_14 Histidine kinase - - - 0.000000000000000000000000000000000000000000000007241 193.0
HFD3_k127_4263800_15 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000005853 155.0
HFD3_k127_4263800_16 spore germination - - - 0.000000000000000000000000000000000000656 152.0
HFD3_k127_4263800_17 CHRD domain - - - 0.0000000000000000000000000000000008205 145.0
HFD3_k127_4263800_18 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000004925 134.0
HFD3_k127_4263800_19 AI-2E family transporter - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000000000000000000001508 117.0
HFD3_k127_4263800_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 377.0
HFD3_k127_4263800_20 - - - - 0.000000000000000000000001849 109.0
HFD3_k127_4263800_21 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000003026 108.0
HFD3_k127_4263800_22 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000002112 105.0
HFD3_k127_4263800_23 - - - - 0.00000000000000003765 96.0
HFD3_k127_4263800_24 recombinase activity K07450 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000009213 87.0
HFD3_k127_4263800_25 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000003044 79.0
HFD3_k127_4263800_26 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.000000000001229 79.0
HFD3_k127_4263800_27 CarboxypepD_reg-like domain K13276 - - 0.00000006399 64.0
HFD3_k127_4263800_28 - - - - 0.0000002811 63.0
HFD3_k127_4263800_29 Urate oxidase N-terminal - - - 0.000008527 55.0
HFD3_k127_4263800_3 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 342.0
HFD3_k127_4263800_30 Polyketide cyclase / dehydrase and lipid transport - - - 0.00001312 55.0
HFD3_k127_4263800_32 ATP-binding protein K11710 - - 0.0001081 48.0
HFD3_k127_4263800_4 PFAM Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 313.0
HFD3_k127_4263800_5 Pterin binding enzyme K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 295.0
HFD3_k127_4263800_6 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003507 260.0
HFD3_k127_4263800_7 PFAM Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000001583 271.0
HFD3_k127_4263800_8 ABC 3 transport family K09819 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003506 256.0
HFD3_k127_4263800_9 Domain of unknown function (DUF4331) - - - 0.00000000000000000000000000000000000000000000000000000000000000000007657 256.0
HFD3_k127_4313736_0 4-Hydroxyphenylpyruvate dioxygenase K00457,K16421 GO:0003674,GO:0003824,GO:0003868,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0051213,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.27,1.13.11.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008422 495.0
HFD3_k127_4313736_1 Required for the activity of the bacterial periplasmic transport system of putrescine K02055 GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042618,GO:0042619,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071704,GO:0071705,GO:0098657,GO:1901440,GO:1901441,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 491.0
HFD3_k127_4313736_10 ECF sigma factor K03088 - - 0.00000000000000000000002932 107.0
HFD3_k127_4313736_11 Histidine kinase - - - 0.00000000000000003281 96.0
HFD3_k127_4313736_12 DNA-binding protein K06204 - - 0.0000000000000009873 82.0
HFD3_k127_4313736_13 Family of unknown function (DUF5317) - - - 0.0000000000004767 79.0
HFD3_k127_4313736_15 - - - - 0.0001857 51.0
HFD3_k127_4313736_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 436.0
HFD3_k127_4313736_3 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 383.0
HFD3_k127_4313736_4 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 321.0
HFD3_k127_4313736_5 ABC-type spermidine putrescine transport system, permease component II K02053 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 327.0
HFD3_k127_4313736_6 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 302.0
HFD3_k127_4313736_7 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001074 285.0
HFD3_k127_4313736_8 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001873 273.0
HFD3_k127_4313736_9 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K05524 - - 0.0000000000000000000000000001691 120.0
HFD3_k127_4360708_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001158 291.0
HFD3_k127_4360708_1 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.00000000000000000000000000000000000000000000000004979 191.0
HFD3_k127_4360708_10 Asp23 family, cell envelope-related function - - - 0.0007702 51.0
HFD3_k127_4360708_2 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.3 0.0000000000000000000000000000000000000000000002072 176.0
HFD3_k127_4360708_3 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000003476 140.0
HFD3_k127_4360708_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000002396 112.0
HFD3_k127_4360708_5 RNA methyltransferase, RsmD family K08316 - 2.1.1.171 0.000000000000000000000005395 109.0
HFD3_k127_4360708_6 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000615 110.0
HFD3_k127_4360708_7 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.0000000000000000003954 95.0
HFD3_k127_4360708_8 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000001475 84.0
HFD3_k127_4360708_9 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000009053 87.0
HFD3_k127_4395001_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008155 579.0
HFD3_k127_4395001_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 574.0
HFD3_k127_4395001_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 440.0
HFD3_k127_4395001_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 301.0
HFD3_k127_4395001_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000001037 183.0
HFD3_k127_4395001_5 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000008934 172.0
HFD3_k127_4395001_6 Peptidoglycan-binding LysM - - - 0.00000000000000000000000000000001627 143.0
HFD3_k127_4460911_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 475.0
HFD3_k127_4460911_1 PFAM Transketolase central region K21417 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 432.0
HFD3_k127_4460911_10 - - - - 0.000000000323 68.0
HFD3_k127_4460911_11 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.000000003049 67.0
HFD3_k127_4460911_2 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183,K11189 - 2.7.1.202,2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 364.0
HFD3_k127_4460911_3 Dehydrogenase E1 component K21416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005738 348.0
HFD3_k127_4460911_4 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000108 216.0
HFD3_k127_4460911_5 protein-phosphocysteine-sugar phosphotransferase activity K02782,K02783 - 2.7.1.198 0.000000000000000000000000000000000000000000000000000104 189.0
HFD3_k127_4460911_6 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity K00991,K12506 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000003574 180.0
HFD3_k127_4460911_7 PTS system glucitol sorbitol-specific IIA component K02781 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009401,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0051179,GO:0051234,GO:0071702 2.7.1.198 0.00000000000000000000000000003542 124.0
HFD3_k127_4460911_8 PTS HPr component phosphorylation site K11189 - - 0.000000000000000004033 86.0
HFD3_k127_4460911_9 Putative sugar-binding domain - - - 0.00000000000005262 82.0
HFD3_k127_4470419_0 Periplasmic binding protein domain K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000001945 241.0
HFD3_k127_4470419_1 PFAM catalytic domain of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000148 229.0
HFD3_k127_4470419_2 pyrroloquinoline quinone binding - - - 0.000000000000000000000000000000000000002044 165.0
HFD3_k127_4470419_3 muconolactone delta-isomerase K03464 - 5.3.3.4 0.00000000000000000000000000384 115.0
HFD3_k127_4470419_4 PFAM biotin lipoyl attachment domain-containing protein - - - 0.0000000000000000000000003515 106.0
HFD3_k127_4470419_5 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 0.0000000002082 62.0
HFD3_k127_448209_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 505.0
HFD3_k127_448209_1 COG0044 Dihydroorotase and related cyclic amidohydrolases K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 392.0
HFD3_k127_448209_10 Transmembrane secretion effector - - - 0.00000000000000000000000000000001133 144.0
HFD3_k127_448209_11 MFS/sugar transport protein - - - 0.0000000000000000000003736 111.0
HFD3_k127_448209_12 Carbon monoxide dehydrogenase subunit G (CoxG) K09386 - - 0.000000000004459 72.0
HFD3_k127_448209_13 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.0000000005224 72.0
HFD3_k127_448209_14 NMT1-like family K02051 - - 0.00001053 58.0
HFD3_k127_448209_15 Divergent 4Fe-4S mono-cluster K05337 - - 0.00001791 49.0
HFD3_k127_448209_2 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 306.0
HFD3_k127_448209_3 X-Pro dipeptidyl-peptidase (S15 family) K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002159 284.0
HFD3_k127_448209_4 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001056 287.0
HFD3_k127_448209_5 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000001611 234.0
HFD3_k127_448209_6 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000001628 206.0
HFD3_k127_448209_7 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000008555 194.0
HFD3_k127_448209_8 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000001686 181.0
HFD3_k127_448209_9 [2Fe-2S] binding domain - - - 0.00000000000000000000000000000000000000002529 162.0
HFD3_k127_4532345_0 Prolyl oligopeptidase family - - - 7.252e-262 824.0
HFD3_k127_4532345_1 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008021 372.0
HFD3_k127_4532345_3 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000007938 124.0
HFD3_k127_4532345_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000006143 108.0
HFD3_k127_4532345_5 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000002917 93.0
HFD3_k127_4532345_6 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000006991 61.0
HFD3_k127_4565321_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 520.0
HFD3_k127_4565321_1 transferase K02851 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000001197 239.0
HFD3_k127_4662577_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 518.0
HFD3_k127_4662577_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009132 491.0
HFD3_k127_4662577_10 C-terminal four TMM region of protein-O-mannosyltransferase K00728 - 2.4.1.109 0.0000000000000000000000000000002491 145.0
HFD3_k127_4662577_11 lipid A biosynthesis acyltransferase K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.265 0.0000000000000000000000000000007479 140.0
HFD3_k127_4662577_12 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000003131 137.0
HFD3_k127_4662577_13 Glycosyl transferase K00728 - 2.4.1.109 0.000000000000000000000000001249 133.0
HFD3_k127_4662577_14 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000001987 121.0
HFD3_k127_4662577_15 PFAM single-stranded nucleic acid binding R3H domain protein K06346 - - 0.000000000000000000000004356 119.0
HFD3_k127_4662577_16 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000006809 100.0
HFD3_k127_4662577_17 Membrane protein insertase, YidC Oxa1 family K03217 - - 0.0000000000005016 81.0
HFD3_k127_4662577_18 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000113 76.0
HFD3_k127_4662577_19 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000001699 62.0
HFD3_k127_4662577_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 353.0
HFD3_k127_4662577_20 protein serine/threonine phosphatase activity - - - 0.0000000001762 75.0
HFD3_k127_4662577_21 Bacterial lipid A biosynthesis acyltransferase K02517,K22311 - 2.3.1.241,2.3.1.265 0.00000004294 66.0
HFD3_k127_4662577_3 Glycosyl transferase 4-like domain K08256 - 2.4.1.345 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 312.0
HFD3_k127_4662577_4 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000002373 226.0
HFD3_k127_4662577_5 (Rhomboid) family K07059 - - 0.00000000000000000000000000000000000000000000000000000000001185 218.0
HFD3_k127_4662577_6 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000002156 222.0
HFD3_k127_4662577_7 outer membrane autotransporter K12287,K12686 - - 0.000000000000000000000000000000000000000000000335 188.0
HFD3_k127_4662577_8 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000003166 153.0
HFD3_k127_4662577_9 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000001057 153.0
HFD3_k127_4671023_0 FAD dependent oxidoreductase central domain - - - 5e-324 1012.0
HFD3_k127_4671023_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 1.637e-238 762.0
HFD3_k127_4671023_10 TIGRFAM competence damage-inducible protein CinA N-terminal domain K03742 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000001591 255.0
HFD3_k127_4671023_11 PFAM Inositol monophosphatase K01092,K05602 - 3.1.3.15,3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000034 222.0
HFD3_k127_4671023_12 - - - - 0.00000000000000000000000000000000000002414 153.0
HFD3_k127_4671023_13 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000004491 148.0
HFD3_k127_4671023_14 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000005819 115.0
HFD3_k127_4671023_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009232 563.0
HFD3_k127_4671023_3 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008978 559.0
HFD3_k127_4671023_4 FAD dependent oxidoreductase central domain K19191 - 1.5.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 432.0
HFD3_k127_4671023_5 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 376.0
HFD3_k127_4671023_6 electron transport chain K00347,K03614,K21163 - 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006678 317.0
HFD3_k127_4671023_7 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000007391 274.0
HFD3_k127_4671023_8 Clp protease K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000944 268.0
HFD3_k127_4671023_9 Choline ethanolamine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004187 265.0
HFD3_k127_4699763_0 Pyridoxal-phosphate dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 481.0
HFD3_k127_4699763_1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000003691 200.0
HFD3_k127_4699763_2 YjbR - - - 0.0000000000000000000000005321 119.0
HFD3_k127_4699763_3 - - - - 0.00000000009533 64.0
HFD3_k127_4718064_0 Calcineurin-like phosphoesterase K01077 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004975 359.0
HFD3_k127_4718064_1 glycosyl transferase, family 39 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 339.0
HFD3_k127_4718064_2 PFAM helix-turn-helix HxlR type - - - 0.00000000000000000000000000000000000000000000000000000005654 211.0
HFD3_k127_4718064_3 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000001196 207.0
HFD3_k127_4718064_4 endonuclease III K01247 - 3.2.2.21 0.00000000000000000000000000000000000000002024 164.0
HFD3_k127_4718064_5 Conserved hypothetical protein (DUF2461) - - - 0.0000000000000000000000000000000000001866 151.0
HFD3_k127_4718064_6 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000005629 100.0
HFD3_k127_4718064_7 antibiotic catabolic process K13277 - - 0.0000000000000000006584 100.0
HFD3_k127_4718064_9 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.00000000004445 66.0
HFD3_k127_4744436_0 Two component transcriptional regulator, LuxR family - - - 0.000000000000000000000000000000000000000000000000000000009071 214.0
HFD3_k127_4744436_1 Pfam:DUF2029 - - - 0.000000000000000000000000000000000000000000009618 175.0
HFD3_k127_4744436_2 Pfam:DUF2029 - - - 0.00000000000000000000000000000000000000000002738 172.0
HFD3_k127_4744436_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07777 - 2.7.13.3 0.000000000000000000000000000000000000000604 163.0
HFD3_k127_4744436_5 Pfam:DUF2029 - - - 0.00000000000000000000000005875 124.0
HFD3_k127_4774497_0 Helix-hairpin-helix motif K14162 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 543.0
HFD3_k127_4774497_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII - - - 0.000000000000000000004425 102.0
HFD3_k127_4774497_2 Helix-turn-helix XRE-family like proteins K07729 - - 0.000000000000004136 79.0
HFD3_k127_4774497_3 - - - - 0.000009839 52.0
HFD3_k127_4780808_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 2.77e-322 1007.0
HFD3_k127_4780808_1 carboxylic acid catabolic process K18334 - 4.2.1.68 9.149e-221 692.0
HFD3_k127_4780808_10 gntR family K05799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008407 247.0
HFD3_k127_4780808_11 Repeat of unknown function (DUF346) - - - 0.00000000000000000000000000000000000000002193 158.0
HFD3_k127_4780808_12 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000008356 127.0
HFD3_k127_4780808_13 TIGRFAM competence protein ComEA helix-hairpin-helix repeat K02237 - - 0.0000000000000000000005775 106.0
HFD3_k127_4780808_14 Putative stress-induced transcription regulator - - - 0.000000000000000000006001 100.0
HFD3_k127_4780808_15 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.0000000000000000005024 101.0
HFD3_k127_4780808_16 Phosphotransferase enzyme family - - - 0.0000000000003626 82.0
HFD3_k127_4780808_17 - - - - 0.000000000182 72.0
HFD3_k127_4780808_18 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00001103 58.0
HFD3_k127_4780808_2 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 522.0
HFD3_k127_4780808_3 Branched-chain amino acid transport system / permease component K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000356 428.0
HFD3_k127_4780808_4 Periplasmic binding protein domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005762 397.0
HFD3_k127_4780808_5 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 368.0
HFD3_k127_4780808_6 amidohydrolase K07046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 317.0
HFD3_k127_4780808_7 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 309.0
HFD3_k127_4780808_8 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 296.0
HFD3_k127_4780808_9 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004427 275.0
HFD3_k127_481151_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 9.996e-292 909.0
HFD3_k127_481151_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.531e-265 841.0
HFD3_k127_481151_10 TrkA-C domain K03499 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000001556 202.0
HFD3_k127_481151_11 Putative sugar-binding domain - - - 0.000000000000000000000000000000000000000006107 165.0
HFD3_k127_481151_12 NYN domain - - - 0.00000000000000000000000000000000000149 158.0
HFD3_k127_481151_13 Cytidylate kinase-like family K00760 - 2.4.2.8 0.0000000000000000000000000000000003742 143.0
HFD3_k127_481151_14 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.000000000000000000000000000000003896 144.0
HFD3_k127_481151_15 Putative NAD(P)-binding K03499 - - 0.000000000000000000000000000002302 134.0
HFD3_k127_481151_16 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000003132 121.0
HFD3_k127_481151_17 AMP binding - - - 0.00000000000000000000006913 106.0
HFD3_k127_481151_18 PFAM MerR family regulatory protein K13640 - - 0.0000000000000000000007388 100.0
HFD3_k127_481151_19 Acylphosphatase K01512 - 3.6.1.7 0.000000000000000000005363 100.0
HFD3_k127_481151_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 404.0
HFD3_k127_481151_20 Metal-sensitive transcriptional repressor K21600 - - 0.00000000000000000002077 95.0
HFD3_k127_481151_21 Acyl-ACP thioesterase - - - 0.00000000001419 76.0
HFD3_k127_481151_3 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006659 336.0
HFD3_k127_481151_4 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009177 327.0
HFD3_k127_481151_5 Belongs to the binding-protein-dependent transport system permease family K01998,K11955 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 316.0
HFD3_k127_481151_6 Belongs to the binding-protein-dependent transport system permease family K01997,K11956 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002103 286.0
HFD3_k127_481151_7 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000001013 235.0
HFD3_k127_481151_8 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002935 239.0
HFD3_k127_481151_9 Heat shock protein DnaJ domain protein K03686,K05516 - - 0.000000000000000000000000000000000000000000000000000000000001346 228.0
HFD3_k127_4832357_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 7.764e-216 688.0
HFD3_k127_4832357_1 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008933 635.0
HFD3_k127_4832357_10 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001621 257.0
HFD3_k127_4832357_11 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000003236 227.0
HFD3_k127_4832357_12 Mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000007826 185.0
HFD3_k127_4832357_13 Mannose-6-phosphate isomerase - - - 0.00000000000000000000000000000007357 136.0
HFD3_k127_4832357_14 FR47-like protein - - - 0.00000000000000000000001803 117.0
HFD3_k127_4832357_15 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000001019 97.0
HFD3_k127_4832357_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007617 550.0
HFD3_k127_4832357_3 Type II/IV secretion system protein K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009541 545.0
HFD3_k127_4832357_4 adenosylhomocysteinase activity K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 544.0
HFD3_k127_4832357_5 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000559 417.0
HFD3_k127_4832357_6 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835,K01840 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 414.0
HFD3_k127_4832357_7 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 365.0
HFD3_k127_4832357_8 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 355.0
HFD3_k127_4832357_9 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 317.0
HFD3_k127_4843181_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1059.0
HFD3_k127_4843181_1 ABC transporter K06147 - - 3.003e-245 776.0
HFD3_k127_4843181_10 Cysteine desulfurase family protein, VC1184 subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 415.0
HFD3_k127_4843181_11 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 412.0
HFD3_k127_4843181_12 Exporter of polyketide antibiotics K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004891 381.0
HFD3_k127_4843181_13 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008114 323.0
HFD3_k127_4843181_14 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 327.0
HFD3_k127_4843181_15 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 309.0
HFD3_k127_4843181_16 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000866 312.0
HFD3_k127_4843181_17 Helix-hairpin-helix class 2 (Pol1 family) motifs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 306.0
HFD3_k127_4843181_18 Acetylornithine deacetylase K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002083 282.0
HFD3_k127_4843181_19 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004393 278.0
HFD3_k127_4843181_2 Adenosine/AMP deaminase K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 518.0
HFD3_k127_4843181_20 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002627 263.0
HFD3_k127_4843181_21 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000006419 263.0
HFD3_k127_4843181_22 Malate/L-lactate dehydrogenase K00073 - 1.1.1.350 0.0000000000000000000000000000000000000000000000000000000000000002478 241.0
HFD3_k127_4843181_23 Amidinotransferase - - - 0.000000000000000000000000000000000000000000000000000000009319 216.0
HFD3_k127_4843181_24 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000006962 204.0
HFD3_k127_4843181_25 Isochorismatase family K08281 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006769,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0071704,GO:0072524,GO:1901360,GO:1901564 3.5.1.19 0.000000000000000000000000000000000000000000000000000001415 199.0
HFD3_k127_4843181_26 Iron permease FTR1 K07243 - - 0.000000000000000000000000000000000000000000000000000005381 201.0
HFD3_k127_4843181_27 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000001415 200.0
HFD3_k127_4843181_28 Protein of unknown function (DUF1684) K09164 - - 0.00000000000000000000000000000000000000000000000006357 195.0
HFD3_k127_4843181_29 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000006949 180.0
HFD3_k127_4843181_3 Large extracellular alpha-helical protein K06894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 556.0
HFD3_k127_4843181_30 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.0000000000000000000000000000000000000000007065 169.0
HFD3_k127_4843181_31 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000001883 163.0
HFD3_k127_4843181_32 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000002651 153.0
HFD3_k127_4843181_33 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000006307 151.0
HFD3_k127_4843181_34 Protein of unknown function (DUF4242) - - - 0.0000000000000000000000000000000000009142 140.0
HFD3_k127_4843181_35 Cupin domain - - - 0.0000000000000000000000000000000008052 136.0
HFD3_k127_4843181_36 integral membrane protein - - - 0.0000000000000000000000000000004545 134.0
HFD3_k127_4843181_37 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000001291 130.0
HFD3_k127_4843181_38 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.000000000000000000000000004171 119.0
HFD3_k127_4843181_39 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity - - - 0.00000000000000000000000004238 126.0
HFD3_k127_4843181_4 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004546 523.0
HFD3_k127_4843181_40 Regulates arginine biosynthesis genes K03402 - - 0.000000000000000000001009 102.0
HFD3_k127_4843181_41 pyridoxamine 5'-phosphate K07005 - - 0.000000000000000000008315 98.0
HFD3_k127_4843181_42 family transcriptional regulator K13652 - - 0.000000000000000171 87.0
HFD3_k127_4843181_43 PFAM OsmC family protein K07397 - - 0.0000000000000142 82.0
HFD3_k127_4843181_44 Uncharacterized protein conserved in bacteria (DUF2255) - - - 0.0000003198 59.0
HFD3_k127_4843181_45 Proprotein convertase P-domain - - - 0.000001286 60.0
HFD3_k127_4843181_46 Acetylornithine deacetylase K01438 - 3.5.1.16 0.000001394 57.0
HFD3_k127_4843181_5 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 482.0
HFD3_k127_4843181_6 FAD dependent oxidoreductase K00109,K15736 - 1.1.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005121 469.0
HFD3_k127_4843181_7 purine-nucleoside phosphorylase activity K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 437.0
HFD3_k127_4843181_8 argininosuccinate lyase K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 450.0
HFD3_k127_4843181_9 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 418.0
HFD3_k127_4905990_0 DegT/DnrJ/EryC1/StrS aminotransferase family K04127 - 5.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008421 406.0
HFD3_k127_4905990_1 response regulator receiver K07668,K07775 - - 0.000000000000000000000000000000000003393 152.0
HFD3_k127_4905990_2 histidine kinase HAMP region domain protein K07636 - 2.7.13.3 0.00000000000000000000000001399 127.0
HFD3_k127_4905990_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000281 98.0
HFD3_k127_4905990_4 ATP-binding region, ATPase domain protein - - - 0.0000000000000005771 93.0
HFD3_k127_4908475_0 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 399.0
HFD3_k127_4908475_1 Glycine cleavage T-protein C-terminal barrel domain K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 375.0
HFD3_k127_4908475_10 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000001945 126.0
HFD3_k127_4908475_11 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.0000000000000000000000006706 115.0
HFD3_k127_4908475_12 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.000000000379 63.0
HFD3_k127_4908475_13 Anti-sigma-K factor rskA - - - 0.000001597 60.0
HFD3_k127_4908475_2 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000813 362.0
HFD3_k127_4908475_3 PFAM aspartate ornithine carbamoyltransferase, Asp Orn-binding region K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 351.0
HFD3_k127_4908475_4 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 320.0
HFD3_k127_4908475_5 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000001716 275.0
HFD3_k127_4908475_6 Belongs to the purine pyrimidine phosphoribosyltransferase family. PyrR subfamily K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000704 231.0
HFD3_k127_4908475_7 Pyridoxal-dependent decarboxylase conserved domain - - - 0.0000000000000000000000000000000000000000000000000000000000003341 232.0
HFD3_k127_4908475_8 membrane - - - 0.0000000000000000000000000000000000000000000000000000001301 203.0
HFD3_k127_4908475_9 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000003932 172.0
HFD3_k127_4914004_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 486.0
HFD3_k127_4914004_1 Helix-hairpin-helix DNA-binding, class 1 K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006712 494.0
HFD3_k127_4914004_2 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 446.0
HFD3_k127_4914004_3 Sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 353.0
HFD3_k127_4914004_4 Protein of unknown function (DUF3048) C-terminal domain - - - 0.0000000000000000000000000000000000000000002202 177.0
HFD3_k127_4914004_5 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000006439 172.0
HFD3_k127_4914004_6 cell envelope-related transcriptional attenuator - - - 0.00000000000000000000000000000000000007078 160.0
HFD3_k127_4914004_7 PFAM Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000004875 134.0
HFD3_k127_4914004_8 Glucose / Sorbosone dehydrogenase - - - 0.000000292 59.0
HFD3_k127_4923168_0 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 423.0
HFD3_k127_4923168_1 Binding-protein-dependent transport system inner membrane component K02025,K10118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 347.0
HFD3_k127_4923168_2 Binding-protein-dependent transport system inner membrane component K17317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000084 325.0
HFD3_k127_4923168_3 Magnesium transport protein CorA K03284 - - 0.0000000000000000000000000000000000000000000002256 182.0
HFD3_k127_4923168_4 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000652 136.0
HFD3_k127_4923168_5 Histidine kinase K07675 - 2.7.13.3 0.00000000000000000000008386 114.0
HFD3_k127_4923168_6 Domain of unknown function (DUF4349) - - - 0.0000000000000000000001707 110.0
HFD3_k127_4923168_7 domain, Protein - - - 0.0000000007036 69.0
HFD3_k127_4938909_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 5.647e-195 634.0
HFD3_k127_4938909_1 tryptophan synthase activity K01696,K06001 - 4.2.1.20 4.768e-194 620.0
HFD3_k127_4938909_10 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000004658 237.0
HFD3_k127_4938909_11 TIGRFAM DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000004431 203.0
HFD3_k127_4938909_12 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000007262 170.0
HFD3_k127_4938909_13 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000006041 164.0
HFD3_k127_4938909_14 phosphoesterase (MutT family) - - - 0.00000000000000000000000000000001826 136.0
HFD3_k127_4938909_15 Prephenate dehydrogenase K15226 - 1.3.1.78 0.0000000000000000000000000000001058 141.0
HFD3_k127_4938909_16 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000006811 129.0
HFD3_k127_4938909_17 PFAM Methicillin resistance protein - - - 0.0000003309 61.0
HFD3_k127_4938909_18 - - - - 0.000051 54.0
HFD3_k127_4938909_2 Peptidase dimerisation domain K01436,K01438,K01439 - 3.5.1.16,3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 491.0
HFD3_k127_4938909_3 Among the AAA ATPases, the YifB protease family belongs to the Helix 2 insert clade K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 398.0
HFD3_k127_4938909_4 PFAM band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 308.0
HFD3_k127_4938909_5 PFAM Sodium calcium exchanger protein K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 296.0
HFD3_k127_4938909_6 Participates in initiation and elongation during chromosome replication K02314,K02316,K17680 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000005192 253.0
HFD3_k127_4938909_7 PFAM response regulator receiver K02282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005954 256.0
HFD3_k127_4938909_8 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000002133 259.0
HFD3_k127_4938909_9 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000005902 245.0
HFD3_k127_4949322_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.078e-249 791.0
HFD3_k127_4949322_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003 275.0
HFD3_k127_4949322_2 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001305 286.0
HFD3_k127_4949322_3 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000003748 234.0
HFD3_k127_4949322_4 Belongs to the carbohydrate kinase PfkB family - - - 0.0000000000000000000000000000000000000005462 161.0
HFD3_k127_4949322_5 Putative Phosphatase - - - 0.0000000000000000000000000000006181 133.0
HFD3_k127_4949322_6 PFAM sigma-70 region 2 domain protein K03088 - - 0.00000000000000000000905 99.0
HFD3_k127_4949322_7 galactose-6-phosphate isomerase activity K01808 - 5.3.1.6 0.000000000003174 78.0
HFD3_k127_4949322_8 Cyclic-di-AMP receptor - - - 0.00000000004211 70.0
HFD3_k127_4949322_9 - - - - 0.0000005346 59.0
HFD3_k127_4996379_0 Proline racemase K01777 - 5.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 383.0
HFD3_k127_4996379_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 360.0
HFD3_k127_4996379_2 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000009679 232.0
HFD3_k127_4996379_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000808 208.0
HFD3_k127_4996379_4 guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000007216 165.0
HFD3_k127_4996379_5 Superoxide dismutase K00518 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.15.1.1 0.00000000000000000000000000000000007235 142.0
HFD3_k127_4996379_6 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000004425 135.0
HFD3_k127_4996379_7 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000001334 73.0
HFD3_k127_4996379_8 Peptidoglycan-binding lysin domain - - - 0.00001496 58.0
HFD3_k127_5021257_0 Permease family K06901 GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015208,GO:0015851,GO:0015854,GO:0016020,GO:0022857,GO:0035344,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:0098657,GO:0098710,GO:0098739,GO:1903716,GO:1904823 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005188 423.0
HFD3_k127_5021257_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000735 115.0
HFD3_k127_5021257_2 - - - - 0.0006389 51.0
HFD3_k127_5026430_0 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000251 213.0
HFD3_k127_5026430_1 aminopeptidase activity - - - 0.000000000000000000000000000000000000000003948 166.0
HFD3_k127_5026430_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000004218 84.0
HFD3_k127_5040841_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.878e-258 816.0
HFD3_k127_5040841_1 tRNA binding K04566 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 411.0
HFD3_k127_5040841_2 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001899 289.0
HFD3_k127_5040841_3 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000002625 227.0
HFD3_k127_5040841_4 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000005542 187.0
HFD3_k127_5040841_5 Seryl-tRNA synthetase N-terminal domain K01875 - 6.1.1.11 0.00000000000000000000000000000000000000007886 165.0
HFD3_k127_5040841_6 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000001352 159.0
HFD3_k127_5040841_7 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000004216 138.0
HFD3_k127_5040841_8 Regulates arginine biosynthesis genes K03402 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006355,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901605,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000001577 121.0
HFD3_k127_5040841_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000008024 79.0
HFD3_k127_505510_0 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003919 453.0
HFD3_k127_505510_1 Secretory lipase - - - 0.0000000000000000000000000000000000000000000000001277 195.0
HFD3_k127_505510_2 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000001522 177.0
HFD3_k127_505510_3 Flavodoxin domain K00230 - 1.3.5.3 0.000000000000000000000000000000006809 135.0
HFD3_k127_505510_4 Domain of unknown function (DU1801) - - - 0.0000000000000003255 84.0
HFD3_k127_505510_5 integral membrane protein - - - 0.000000000000004056 88.0
HFD3_k127_505510_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000578 54.0
HFD3_k127_5149760_0 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 517.0
HFD3_k127_5149760_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 385.0
HFD3_k127_5149760_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 307.0
HFD3_k127_5149760_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 303.0
HFD3_k127_5149760_4 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000003706 215.0
HFD3_k127_5149760_5 biotin acetyl-CoA-carboxylase ligase K03524 - 6.3.4.15 0.000000000000000000000000000000000001731 159.0
HFD3_k127_5149760_6 Sigma-70 region 2 K03088 - - 0.000000000000000000000002305 112.0
HFD3_k127_5149760_7 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000002416 63.0
HFD3_k127_5264183_0 Uridine phosphorylase K00757 - 2.4.2.3 0.000000000000000000000000000000000000000000000000000000000000000001849 237.0
HFD3_k127_5264183_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000002356 164.0
HFD3_k127_5264183_2 PFAM ROK family protein K00845 - 2.7.1.2 0.0000000000000000002699 93.0
HFD3_k127_5264183_3 - - - - 0.00000000000000718 76.0
HFD3_k127_5264183_4 PFAM Endonuclease exonuclease phosphatase K07004 - - 0.000000000004437 81.0
HFD3_k127_5264183_5 - - - - 0.000000004318 71.0
HFD3_k127_5298837_0 Fungal trichothecene efflux pump (TRI12) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007976 391.0
HFD3_k127_5298837_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 335.0
HFD3_k127_5298837_2 peptidase - - - 0.0000000000000000000000000000000000000000000000000009315 203.0
HFD3_k127_5298837_3 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000008666 112.0
HFD3_k127_5298837_4 competence protein COMEC - - - 0.00000000000000000000001598 114.0
HFD3_k127_5298837_5 F420H(2)-dependent quinone reductase - - - 0.0000000000000000006313 94.0
HFD3_k127_5308967_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.613e-229 721.0
HFD3_k127_5308967_1 TatD family K03424 - - 0.000000000000000000000000000000000000000001908 168.0
HFD3_k127_5308967_2 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000003766 142.0
HFD3_k127_5308967_3 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.00000000000000002505 86.0
HFD3_k127_5308967_4 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000001574 75.0
HFD3_k127_5363734_0 ABC transporter, transmembrane region K06147 - - 2.519e-268 849.0
HFD3_k127_5363734_1 ABC transporter, transmembrane region K06147 - - 3.586e-214 681.0
HFD3_k127_5363734_10 PFAM LmbE family protein - - - 0.00000000000000000000000000000000000000000000000000000006089 205.0
HFD3_k127_5363734_11 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K00982,K03564 - 1.11.1.15,2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000000000000000007271 198.0
HFD3_k127_5363734_12 Helix-turn-helix type 11 domain protein K13572 - - 0.000000000000000000000000000000000000000000000000125 187.0
HFD3_k127_5363734_13 FR47-like protein K06976 - - 0.0000000000000000000000000000000000000000000000482 182.0
HFD3_k127_5363734_14 ECF-type riboflavin transporter, S component K16924 - - 0.00000000000000000000000000000000000000000001914 168.0
HFD3_k127_5363734_15 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000005801 179.0
HFD3_k127_5363734_16 Polysaccharide deacetylase K22278 - 3.5.1.104 0.00000000000000000000000000000000000001692 158.0
HFD3_k127_5363734_17 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000004661 141.0
HFD3_k127_5363734_18 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.0000000000000000000000000000000005187 153.0
HFD3_k127_5363734_19 Thiamin pyrophosphokinase, vitamin B1 binding domain K00949 - 2.7.6.2 0.000000000000000000000000000000001074 139.0
HFD3_k127_5363734_2 ATPases associated with a variety of cellular activities K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 518.0
HFD3_k127_5363734_20 YbaK prolyl-tRNA synthetase associated region - - - 0.00000000000000000000000000000000389 137.0
HFD3_k127_5363734_21 Rieske 2Fe-2S - - - 0.0000000000000000000001234 108.0
HFD3_k127_5363734_22 Uncharacterized conserved protein (DUF2203) - - - 0.00000000000000000002873 95.0
HFD3_k127_5363734_23 glycolate biosynthetic process K01091,K06019,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.18,3.6.1.1 0.000000000000000002851 94.0
HFD3_k127_5363734_24 MarR family - - - 0.00000000002953 72.0
HFD3_k127_5363734_25 Domain of unknown function (DUF309) K09763 - - 0.000000002564 66.0
HFD3_k127_5363734_26 Kelch motif - - - 0.000000009672 68.0
HFD3_k127_5363734_3 PFAM aminotransferase, class I K00812,K10907 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 461.0
HFD3_k127_5363734_4 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006395 447.0
HFD3_k127_5363734_5 D-isomer specific 2-hydroxyacid dehydrogenase K00015,K15893 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000444 377.0
HFD3_k127_5363734_6 Exporter of polyketide antibiotics K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006655 375.0
HFD3_k127_5363734_7 Cytochrome b/b6/petB K03891 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000592 337.0
HFD3_k127_5363734_8 transmembrane transporter activity K16785,K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000003631 235.0
HFD3_k127_5363734_9 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000000000001999 234.0
HFD3_k127_5369333_0 Protein of unknown function (DUF455) - - - 0.0000000000000000001058 99.0
HFD3_k127_5369333_1 Protein of unknown function (DUF455) K11529 - 2.7.1.165 0.000000000000000009072 93.0
HFD3_k127_5369333_3 protein conserved in bacteria - - - 0.000001024 59.0
HFD3_k127_5369333_4 Peptidase S24-like K13280 - 3.4.21.89 0.00001508 53.0
HFD3_k127_5369333_5 HPr Serine kinase C-terminal domain - - - 0.000129 55.0
HFD3_k127_5442115_0 Lipase maturation factor - - - 2.113e-196 626.0
HFD3_k127_5442115_1 Belongs to the aldehyde dehydrogenase family K09472 - 1.2.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005682 617.0
HFD3_k127_5442115_10 sequence-specific DNA binding K01356,K22299 - 3.4.21.88 0.000000000000007002 79.0
HFD3_k127_5442115_11 - - - - 0.000000000001686 76.0
HFD3_k127_5442115_12 Antibiotic biosynthesis monooxygenase - - - 0.000000000424 70.0
HFD3_k127_5442115_14 glyoxalase III activity - - - 0.00000308 57.0
HFD3_k127_5442115_15 YGGT family - - - 0.000003599 55.0
HFD3_k127_5442115_2 NAD(P)-binding Rossmann-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 507.0
HFD3_k127_5442115_3 Bacterial-like globin K06886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 479.0
HFD3_k127_5442115_4 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 GO:0000287,GO:0003674,GO:0003824,GO:0004016,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006171,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009187,GO:0009190,GO:0009259,GO:0009260,GO:0009975,GO:0009987,GO:0016020,GO:0016829,GO:0016849,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0023052,GO:0030145,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046058,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052652,GO:0055086,GO:0065007,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000007561 245.0
HFD3_k127_5442115_5 Major intrinsic protein - - - 0.000000000000000000000000000000000000000000000000000000000002399 217.0
HFD3_k127_5442115_6 Stage II sporulation protein K06381 - - 0.00000000000000000000000000000000009872 154.0
HFD3_k127_5442115_7 VIT family - - - 0.000000000000000000000000007481 121.0
HFD3_k127_5442115_8 PFAM DinB family protein - - - 0.0000000000000000000000006005 111.0
HFD3_k127_5442115_9 - - - - 0.0000000000000000744 85.0
HFD3_k127_5462143_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 614.0
HFD3_k127_5462143_1 FtsK SpoIIIE K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 478.0
HFD3_k127_5462143_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 323.0
HFD3_k127_5462143_3 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000001421 207.0
HFD3_k127_5462143_4 TIGRFAM competence damage-inducible protein CinA K03742,K03743 - 3.5.1.42 0.0000000000000000000000000000001582 142.0
HFD3_k127_5462143_5 Domain of unknown function (DUF4115) - - - 0.00000000000005123 85.0
HFD3_k127_5462143_6 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000007142 65.0
HFD3_k127_5462143_7 Fibronectin type 3 domain - - - 0.00002325 57.0
HFD3_k127_548545_0 Phosphofructokinase K00850,K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 445.0
HFD3_k127_548545_1 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 383.0
HFD3_k127_548545_10 - - - - 0.000000000005396 69.0
HFD3_k127_548545_2 Alternative locus ID K00020,K00042 - 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 317.0
HFD3_k127_548545_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 310.0
HFD3_k127_548545_4 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000006385 273.0
HFD3_k127_548545_5 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002687 255.0
HFD3_k127_548545_6 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000004046 238.0
HFD3_k127_548545_7 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000002788 125.0
HFD3_k127_548545_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000002538 104.0
HFD3_k127_548545_9 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000147 98.0
HFD3_k127_5496778_0 Belongs to the thiolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 387.0
HFD3_k127_5496778_1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008929 307.0
HFD3_k127_5496778_2 Belongs to the thiolase family K00626,K02615 - 2.3.1.174,2.3.1.223,2.3.1.9 0.00000000000000000000000000000000000000000000000000000001131 199.0
HFD3_k127_5496778_3 Phenylacetate-CoA oxygenase K02611 - 1.14.13.149 0.0000000000000000000000000000000000000000000000004085 187.0
HFD3_k127_5496778_4 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000002472 184.0
HFD3_k127_5496778_5 Pfam:DUF59 K02612 - - 0.0000000000000000000000000000000000001811 158.0
HFD3_k127_5496778_6 Belongs to the HesB IscA family K13628,K15724 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009061,GO:0009987,GO:0010467,GO:0015980,GO:0016020,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055114,GO:0071704,GO:0071840,GO:0071944,GO:1901564 - 0.00000000000000000000000000000001559 134.0
HFD3_k127_5496778_7 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000001175 123.0
HFD3_k127_5496778_8 - - - - 0.0000000000000000000002992 106.0
HFD3_k127_5498421_0 Pfam:Pyridox_oxidase K07006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001634 269.0
HFD3_k127_5498421_1 DsrE/DsrF-like family - - - 0.00000000000000000000000000000000000000000000000001019 182.0
HFD3_k127_5581317_0 Type II/IV secretion system protein K02283 - - 3.635e-203 639.0
HFD3_k127_5581317_1 Type II secretion system (T2SS), protein F K12511 - - 0.000000000000000000000000000000000000000000000000000000000000000002522 250.0
HFD3_k127_5581317_2 Type II secretion system (T2SS), protein F K12510 - - 0.0000000000000000000000000000000000000000000000000000000000034 222.0
HFD3_k127_5581317_3 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000008587 183.0
HFD3_k127_5581317_4 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000000000000000000000009611 136.0
HFD3_k127_5581317_5 competence protein - - - 0.000000000000000000000000000208 123.0
HFD3_k127_5581317_6 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000005813 99.0
HFD3_k127_5581317_7 Uncharacterized protein conserved in bacteria (DUF2087) - - - 0.00000000000000003794 87.0
HFD3_k127_5631422_0 Cytochrome C and Quinol oxidase polypeptide I K04561 - 1.7.2.5 6.921e-200 647.0
HFD3_k127_5631422_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005667 454.0
HFD3_k127_5631422_10 SnoaL-like domain - - - 0.000000000000003721 83.0
HFD3_k127_5631422_11 translation initiation factor activity - - - 0.0000000000009922 73.0
HFD3_k127_5631422_12 Major facilitator Superfamily - - - 0.0000001742 63.0
HFD3_k127_5631422_2 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 304.0
HFD3_k127_5631422_3 Serine threonine protein kinase involved in cell cycle control - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001366 297.0
HFD3_k127_5631422_5 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000007749 190.0
HFD3_k127_5631422_6 PFAM Flavodoxin K03809 - 1.6.5.2 0.000000000000000000000000000000000000000287 159.0
HFD3_k127_5631422_7 COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) K05770 - - 0.00000000000000000000000000000000000003215 150.0
HFD3_k127_5631422_8 Protein of unknown function (DUF1684) K09164 - - 0.0000000000000000000000000000000000002452 152.0
HFD3_k127_5631422_9 Protein of unknown function (DUF3037) - - - 0.0000000000000000000000000000000003101 140.0
HFD3_k127_5638784_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000001068 212.0
HFD3_k127_5638784_1 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000007796 98.0
HFD3_k127_5638784_2 N-acetylglucosaminylinositol deacetylase activity - - - 0.000000000000000003311 96.0
HFD3_k127_5638784_3 Acetylglucosaminylphosphatidylinositol deacetylase - - - 0.0005669 51.0
HFD3_k127_5685057_0 Carbamoyl-phosphate synthase K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 9.596e-284 913.0
HFD3_k127_5685057_1 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 441.0
HFD3_k127_5685057_10 SOS response associated peptidase (SRAP) - - - 0.0000000000000000000000000000000000000000000000000000000001403 216.0
HFD3_k127_5685057_11 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000001736 207.0
HFD3_k127_5685057_12 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000009947 190.0
HFD3_k127_5685057_13 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000738 160.0
HFD3_k127_5685057_14 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000000000000002182 171.0
HFD3_k127_5685057_15 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000003891 160.0
HFD3_k127_5685057_16 Histidine kinase-like ATPases K07642 - 2.7.13.3 0.00000000000000000000000000000001118 144.0
HFD3_k127_5685057_17 PFAM Rhomboid family protein K19225 - 3.4.21.105 0.00000000000000000000000003712 123.0
HFD3_k127_5685057_18 MobA-like NTP transferase domain - - - 0.000000000000000000001079 110.0
HFD3_k127_5685057_19 Acetyltransferase (GNAT) family - - - 0.00000000000000000003539 106.0
HFD3_k127_5685057_2 PFAM ATPase associated with various cellular activities, AAA_5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 384.0
HFD3_k127_5685057_20 helix_turn_helix, Lux Regulon - - - 0.00000000000000000007669 103.0
HFD3_k127_5685057_21 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000004788 97.0
HFD3_k127_5685057_22 DREV methyltransferase - - - 0.000000000000009438 88.0
HFD3_k127_5685057_23 carbon monoxide dehydrogenase subunit G K09386 - - 0.00000000000001258 79.0
HFD3_k127_5685057_24 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000005535 76.0
HFD3_k127_5685057_25 PFAM TadE family protein - - - 0.0000003225 62.0
HFD3_k127_5685057_27 - - - - 0.000135 51.0
HFD3_k127_5685057_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006986 387.0
HFD3_k127_5685057_4 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009404 351.0
HFD3_k127_5685057_5 VWA domain containing CoxE-like protein K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 316.0
HFD3_k127_5685057_6 RsgA GTPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000014 311.0
HFD3_k127_5685057_7 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002509 284.0
HFD3_k127_5685057_8 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002819 277.0
HFD3_k127_5685057_9 response regulator K07668,K07775 - - 0.00000000000000000000000000000000000000000000000000000000000000008018 231.0
HFD3_k127_569312_0 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 366.0
HFD3_k127_569312_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003077 252.0
HFD3_k127_569312_2 PFAM short-chain dehydrogenase reductase SDR K00068,K03366,K08261 - 1.1.1.140,1.1.1.304,1.1.1.76,1.1.99.21 0.0000000000000000000000000000000000004117 150.0
HFD3_k127_569312_3 Amidohydrolase - - - 0.000000000000000000000000000000000005529 139.0
HFD3_k127_569312_4 Mandelate racemase muconate lactonizing enzyme - - - 0.00000003088 57.0
HFD3_k127_5738116_0 PFAM amine oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 446.0
HFD3_k127_5738116_1 Participates in initiation and elongation during chromosome replication K02314 GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000003969 225.0
HFD3_k127_5738116_2 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.000000000000000000000000000000000000000000000000001649 190.0
HFD3_k127_5738116_3 Binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000007321 128.0
HFD3_k127_5738116_4 chaperone-mediated protein folding - - - 0.00000000000000000002359 104.0
HFD3_k127_5738116_5 SnoaL-like domain - - - 0.000000000000000004034 91.0
HFD3_k127_5738116_6 Protein of unknown function (DUF1232) - - - 0.0000595 53.0
HFD3_k127_5768615_0 glutamine synthetase K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005606 592.0
HFD3_k127_5768615_1 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 345.0
HFD3_k127_5768615_10 Domain of unknown function (DUF378) K09779 - - 0.00000000001248 69.0
HFD3_k127_5768615_11 Ethyl tert-butyl ether degradation - - - 0.00000001498 66.0
HFD3_k127_5768615_12 Protein of unknown function (DUF1444) - - - 0.000008293 58.0
HFD3_k127_5768615_2 PFAM Enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 289.0
HFD3_k127_5768615_3 PFAM phenylacetic acid catabolic family protein K02609 - 1.14.13.149 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002377 271.0
HFD3_k127_5768615_4 PFAM Enoyl-CoA hydratase isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000003816 258.0
HFD3_k127_5768615_5 helix_turn_helix, mercury resistance K22491 - - 0.000000000000000000000000000000000000000000000000000000000001455 222.0
HFD3_k127_5768615_6 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000003761 150.0
HFD3_k127_5768615_7 PFAM flavin reductase domain protein, FMN-binding K16048 - - 0.00000000000000000000000000000000003484 143.0
HFD3_k127_5768615_8 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.00000000000000000000000000000000006294 148.0
HFD3_k127_5768615_9 Serine aminopeptidase, S33 - - - 0.000000000000000000005216 104.0
HFD3_k127_5834290_0 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 470.0
HFD3_k127_5834290_1 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007244 276.0
HFD3_k127_5834290_2 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily K00973,K02617 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000003117 208.0
HFD3_k127_5834290_3 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.0000000000000000000000007007 121.0
HFD3_k127_5834290_4 PFAM polysaccharide biosynthesis protein - - - 0.0000000000000000000000009148 120.0
HFD3_k127_5834290_5 PFAM O-Antigen K18814 - - 0.0000000000000000000004433 112.0
HFD3_k127_5859091_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007954 463.0
HFD3_k127_5859091_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 295.0
HFD3_k127_5859091_2 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000001042 261.0
HFD3_k127_5859091_3 Required for chromosome condensation and partitioning K03529 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000001189 226.0
HFD3_k127_5859091_4 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000001257 141.0
HFD3_k127_5859091_5 Ribosomal protein S16 K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000004887 113.0
HFD3_k127_5859091_6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.000000000000000000002603 102.0
HFD3_k127_5859091_7 Belongs to the UPF0109 family K06960 - - 0.0000000000000000002145 94.0
HFD3_k127_5859091_8 Protein of unknown function (DUF3352) - - - 0.00002396 58.0
HFD3_k127_5868413_0 Ferric reductase like transmembrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006804 407.0
HFD3_k127_5868413_1 ApbE family - - - 0.000000000000000000000000000000000000000000000000000000000000000002545 242.0
HFD3_k127_5868413_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000001171 231.0
HFD3_k127_5868413_3 FMN_bind - - - 0.000000000000000000004646 101.0
HFD3_k127_5968775_0 TIGRFAM Na H antiporter, bacterial form K03316 GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042592,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098719,GO:0098739,GO:0098771,GO:0099516,GO:0099587,GO:1902600 - 0.00000000000000000000000000000004361 132.0
HFD3_k127_5968775_2 Probable zinc-ribbon domain - - - 0.00000000000000000000000001459 119.0
HFD3_k127_5968775_3 Cold-Shock Protein K03704 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0097159,GO:1901363 - 0.00000000805 65.0
HFD3_k127_5968775_5 Receptor family ligand binding region - - - 0.000001832 60.0
HFD3_k127_5997923_0 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 419.0
HFD3_k127_5997923_1 Amidohydrolase family K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 320.0
HFD3_k127_5997923_10 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000002067 128.0
HFD3_k127_5997923_11 Creatinine amidohydrolase - - - 0.00000000001954 77.0
HFD3_k127_5997923_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000172 259.0
HFD3_k127_5997923_3 Branched-chain amino acid transport system / permease component K10440,K17206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007238 261.0
HFD3_k127_5997923_4 Branched-chain amino acid transport system / permease component K10440,K17206 - - 0.0000000000000000000000000000000000000000000000000000000000000000001215 258.0
HFD3_k127_5997923_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000002895 235.0
HFD3_k127_5997923_6 Periplasmic binding protein domain K10439 - - 0.000000000000000000000000000000000000000000000000000000000000004361 230.0
HFD3_k127_5997923_7 Phosphotriesterase family K07048 - - 0.00000000000000000000000000000000000000000000000000000000000002123 241.0
HFD3_k127_5997923_8 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000192 220.0
HFD3_k127_5997923_9 Amidohydrolase - - - 0.0000000000000000000000000000000000000000004294 166.0
HFD3_k127_6053444_0 AAA domain, putative AbiEii toxin, Type IV TA system K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 461.0
HFD3_k127_6053444_1 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 460.0
HFD3_k127_6053444_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 387.0
HFD3_k127_6053444_3 Transport permease protein K09694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 325.0
HFD3_k127_6053444_4 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 315.0
HFD3_k127_6053444_5 Methylates ribosomal protein L11 K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000009685 244.0
HFD3_k127_6053444_6 Uncharacterized protein conserved in bacteria (DUF2334) K22278 - 3.5.1.104 0.00000000000000000000000000000000000000000000000000000000000003202 224.0
HFD3_k127_6053444_7 Transport permease protein K09694 - - 0.0000000000000000000000000000000000000000000000000000000000002752 222.0
HFD3_k127_6053444_8 PFAM Histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000000005561 140.0
HFD3_k127_6053444_9 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.0000009393 58.0
HFD3_k127_6172590_0 FGGY family of carbohydrate kinases, N-terminal domain - - - 2.647e-205 651.0
HFD3_k127_6172590_1 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006827 428.0
HFD3_k127_6172590_10 Protein of unknown function (DUF3090) - - - 0.0000000000000000000000000000000000002778 147.0
HFD3_k127_6172590_11 MgtC family K07507 - - 0.0000000000000000000002097 99.0
HFD3_k127_6172590_12 Protein of unknown function (DUF1003) - - - 0.000000000000000000001798 100.0
HFD3_k127_6172590_2 ribosylpyrimidine nucleosidase activity K01239,K01250,K10213 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006152,GO:0006213,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008477,GO:0009056,GO:0009116,GO:0009119,GO:0009164,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019439,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042454,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0045437,GO:0046131,GO:0046133,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0050263,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658 3.2.2.1,3.2.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 302.0
HFD3_k127_6172590_3 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003038 293.0
HFD3_k127_6172590_4 Phosphatidylinositol - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001117 264.0
HFD3_k127_6172590_5 Belongs to the UPF0271 (lamB) family K07160 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006231 263.0
HFD3_k127_6172590_6 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000006448 228.0
HFD3_k127_6172590_7 Allophanate hydrolase subunit 2 K06350 - - 0.00000000000000000000000000000000000000000000000000005678 203.0
HFD3_k127_6172590_8 NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.000000000000000000000000000000000000000000000003199 189.0
HFD3_k127_6172590_9 Allophanate hydrolase subunit 1 - - - 0.00000000000000000000000000000000000000000006793 177.0
HFD3_k127_6219291_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 1.4e-322 1000.0
HFD3_k127_6219291_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000002619 219.0
HFD3_k127_6219291_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000001317 198.0
HFD3_k127_6219291_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000009033 172.0
HFD3_k127_6219291_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000001785 75.0
HFD3_k127_6236351_0 MgtE intracellular N domain K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 447.0
HFD3_k127_6236351_1 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005091 443.0
HFD3_k127_6236351_10 hyperosmotic response K04065 - - 0.0000000000004508 80.0
HFD3_k127_6236351_11 Cold shock K03704 - - 0.0000000003628 68.0
HFD3_k127_6236351_12 deazaflavin-dependent nitroreductase family protein - - - 0.000000172 61.0
HFD3_k127_6236351_2 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007855 420.0
HFD3_k127_6236351_3 Beta-eliminating lyase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 342.0
HFD3_k127_6236351_4 Belongs to the serpin family K13963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000672 295.0
HFD3_k127_6236351_5 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001766 280.0
HFD3_k127_6236351_6 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768,K12132 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0031224,GO:0031226,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.11.1,5.2.1.8 0.0000000000000000000000000000000000000000001721 164.0
HFD3_k127_6236351_7 AI-2E family transporter - - - 0.00000000000000000000000000000001074 143.0
HFD3_k127_6236351_8 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - - 0.00000000000000000000000000007709 128.0
HFD3_k127_6236351_9 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000006587 121.0
HFD3_k127_6249155_0 DEAD DEAH box helicase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006483 508.0
HFD3_k127_6249155_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 479.0
HFD3_k127_6249155_10 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000001424 278.0
HFD3_k127_6249155_11 PFAM ABC transporter related K02031,K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003068 265.0
HFD3_k127_6249155_12 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000005292 211.0
HFD3_k127_6249155_13 ABC-2 family transporter protein - - - 0.000000000000000000000000000000000000000000000000000001545 205.0
HFD3_k127_6249155_14 PFAM phosphotransferase system PTS sorbose-specific IIC subunit K02795 - - 0.000000000000000000000000000000000000000000000000000002244 206.0
HFD3_k127_6249155_15 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000006795 205.0
HFD3_k127_6249155_16 PFAM HhH-GPD family protein - - - 0.00000000000000000000000000000000000000000000001902 183.0
HFD3_k127_6249155_18 Putative sugar-binding domain - - - 0.0000000000000000000000000000000000002697 157.0
HFD3_k127_6249155_19 PFAM PTS system sorbose subfamily IIB component K02794 - 2.7.1.191 0.000000000000000000000000000000000006084 142.0
HFD3_k127_6249155_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 492.0
HFD3_k127_6249155_20 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.000000000000000000000000000002431 129.0
HFD3_k127_6249155_21 F420H(2)-dependent quinone reductase - - - 0.00000000000000000000000000001483 121.0
HFD3_k127_6249155_22 Protein of unknown function (DUF2089) - - - 0.00000000000000000000000000792 115.0
HFD3_k127_6249155_23 LysE type translocator - - - 0.00000000000000000000000003261 117.0
HFD3_k127_6249155_24 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000213 117.0
HFD3_k127_6249155_25 TIGRFAM endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000004226 109.0
HFD3_k127_6249155_26 cyclic nucleotide binding K09766,K10914 - - 0.000000000000000000004182 102.0
HFD3_k127_6249155_27 Alpha/beta hydrolase family K07020 - - 0.00000000000000002555 94.0
HFD3_k127_6249155_28 Glyoxalase-like domain - - - 0.00000000000000002931 86.0
HFD3_k127_6249155_29 PTS system fructose IIA component K02793 - 2.7.1.191 0.0000000000009798 74.0
HFD3_k127_6249155_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 436.0
HFD3_k127_6249155_30 Putative stress-induced transcription regulator - - - 0.000000000004965 74.0
HFD3_k127_6249155_31 Activator of hsp90 atpase 1 family protein - - - 0.0000000003101 72.0
HFD3_k127_6249155_32 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000003888 61.0
HFD3_k127_6249155_33 Putative adhesin - - - 0.00006488 55.0
HFD3_k127_6249155_34 - - - - 0.0001534 52.0
HFD3_k127_6249155_4 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005605 394.0
HFD3_k127_6249155_5 Belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 387.0
HFD3_k127_6249155_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 376.0
HFD3_k127_6249155_7 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 317.0
HFD3_k127_6249155_8 abc transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 305.0
HFD3_k127_6249155_9 PTS system mannose/fructose/sorbose family IID component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 298.0
HFD3_k127_6252899_0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1321.0
HFD3_k127_6252899_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K03737 - 1.2.7.1 9.136e-194 619.0
HFD3_k127_6252899_2 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 405.0
HFD3_k127_6252899_3 Acetokinase family K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 396.0
HFD3_k127_6252899_4 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000002567 216.0
HFD3_k127_6252899_5 HupF/HypC family K04653 - - 0.000000008114 61.0
HFD3_k127_6314939_0 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003682 350.0
HFD3_k127_6314939_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000001111 160.0
HFD3_k127_6343357_0 PFAM Amidohydrolase 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 357.0
HFD3_k127_6343357_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003765 288.0
HFD3_k127_6343357_10 Bacterial protein of unknown function (DUF881) - - - 0.0000000000000000002293 101.0
HFD3_k127_6343357_11 Bacterial protein of unknown function (DUF951) - - - 0.000000000000001899 89.0
HFD3_k127_6343357_12 Bacterial protein of unknown function (DUF881) - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000008642 84.0
HFD3_k127_6343357_13 Belongs to the peptidase S51 family - - - 0.0006682 51.0
HFD3_k127_6343357_2 PFAM Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000003346 217.0
HFD3_k127_6343357_3 SpoU rRNA Methylase family K03437 - - 0.000000000000000000000000000000000000000000000000000000009847 219.0
HFD3_k127_6343357_4 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000267 214.0
HFD3_k127_6343357_5 transmembrane transport K02035,K15580 - - 0.0000000000000000000000000000000000000000000000000000006144 215.0
HFD3_k127_6343357_7 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000433 200.0
HFD3_k127_6343357_8 Protein of unknown function (DUF664) - - - 0.000000000000000000000000000000000000000000003097 173.0
HFD3_k127_6343357_9 Peptidase MA superfamily - - - 0.000000000000000000000000000000000002405 157.0
HFD3_k127_639012_0 PFAM regulatory protein LuxR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004433 447.0
HFD3_k127_639012_1 RES domain - - - 0.00000000000000000000000000000000000000000862 169.0
HFD3_k127_639012_2 Hemerythrin hhe cation binding - - - 0.00000000000000000000000000000000001172 141.0
HFD3_k127_639012_3 Belongs to the pirin family K06911 - - 0.00000000000000000000000001452 110.0
HFD3_k127_639012_4 - - - - 0.0000000000000000008131 96.0
HFD3_k127_6399774_0 Sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001445 248.0
HFD3_k127_6399774_1 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000009277 163.0
HFD3_k127_6399774_2 phosphatidylinositol metabolic process K13671 - - 0.0000221 57.0
HFD3_k127_6399774_3 O-Antigen ligase - - - 0.0001988 55.0
HFD3_k127_6405578_0 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 343.0
HFD3_k127_6405578_1 Integrase - - - 0.000000000229 68.0
HFD3_k127_6405578_2 Integrase - - - 0.000009482 57.0
HFD3_k127_6450782_0 Dihydropyrimidinase K01464 - 3.5.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004463 488.0
HFD3_k127_6450782_1 Carbon-nitrogen hydrolase K01431 - 3.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008683 439.0
HFD3_k127_6450782_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 351.0
HFD3_k127_6450782_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K15372 - 2.6.1.55 0.00000000000000000000000000000002249 129.0
HFD3_k127_6450782_4 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000003292 139.0
HFD3_k127_6450782_5 Sigma-70 region 2 K03088 - - 0.000000000000001441 84.0
HFD3_k127_6488974_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 623.0
HFD3_k127_6488974_1 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 585.0
HFD3_k127_6488974_10 Belongs to the DNA glycosylase MPG family K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.0000000000000000000000000000000000002213 154.0
HFD3_k127_6488974_11 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000001802 141.0
HFD3_k127_6488974_12 imidazoleglycerol-phosphate dehydratase activity K01693 - 4.2.1.19 0.0000000000000000000000000004239 117.0
HFD3_k127_6488974_13 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000006567 94.0
HFD3_k127_6488974_14 Peptidase A4 family - - - 0.000002807 51.0
HFD3_k127_6488974_15 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000003537 58.0
HFD3_k127_6488974_16 PFAM Colicin V production protein K03558 - - 0.0003034 50.0
HFD3_k127_6488974_2 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 545.0
HFD3_k127_6488974_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000606 372.0
HFD3_k127_6488974_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 361.0
HFD3_k127_6488974_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 314.0
HFD3_k127_6488974_6 PFAM glycosyl transferase, family 51 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004644 299.0
HFD3_k127_6488974_7 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000004218 203.0
HFD3_k127_6488974_8 Histidine biosynthesis bifunctional protein HisIE K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000001124 202.0
HFD3_k127_6488974_9 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000253 194.0
HFD3_k127_6531488_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007023 311.0
HFD3_k127_6531488_1 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000004596 235.0
HFD3_k127_6531488_2 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000005626 212.0
HFD3_k127_6531488_3 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000003984 174.0
HFD3_k127_6531488_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.000000000000000000000000000000000000003594 162.0
HFD3_k127_6531488_5 Imidazoleglycerol-phosphate dehydratase K01089,K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,4.2.1.19 0.0000000000000000000000000000000007559 134.0
HFD3_k127_6531488_6 TIGRFAM TrpR like protein, YerC YecD - - - 0.00000000000000000002221 94.0
HFD3_k127_6545100_0 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 364.0
HFD3_k127_6545100_1 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 342.0
HFD3_k127_6545100_2 Methionine gamma-lyase K01739,K01761 - 2.5.1.48,4.4.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 310.0
HFD3_k127_6545100_3 cytochrome c biogenesis protein K07399 - - 0.000000000000000000000000000000000000000000006891 181.0
HFD3_k127_6545100_4 diguanylate cyclase - - - 0.000000000000000000000000000000000000002246 165.0
HFD3_k127_6545100_5 Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions K02635 GO:0005575,GO:0005622,GO:0005623,GO:0009512,GO:0009579,GO:0016020,GO:0032991,GO:0034357,GO:0042651,GO:0044424,GO:0044436,GO:0044464,GO:0070069 - 0.000000000000000000000006541 117.0
HFD3_k127_6545100_6 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - 0.0007747 43.0
HFD3_k127_6547496_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 1.481e-258 823.0
HFD3_k127_6547496_1 PFAM carbohydrate kinase K00854 - 2.7.1.17 5.47e-203 643.0
HFD3_k127_6547496_10 Belongs to the binding-protein-dependent transport system permease family K10544 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 441.0
HFD3_k127_6547496_11 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009899 403.0
HFD3_k127_6547496_12 ABC transporter K10545 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 357.0
HFD3_k127_6547496_13 Dyp-type peroxidase family K07223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 344.0
HFD3_k127_6547496_14 Oxidoreductase family, C-terminal alpha beta domain K13327 - 1.1.1.384 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 343.0
HFD3_k127_6547496_15 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 326.0
HFD3_k127_6547496_16 PFAM oxidoreductase FAD NAD(P)-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 314.0
HFD3_k127_6547496_17 ROK family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 310.0
HFD3_k127_6547496_18 ABC transporter substrate-binding protein K10543 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005975,GO:0005996,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0015749,GO:0015750,GO:0015753,GO:0019321,GO:0030246,GO:0030288,GO:0030313,GO:0031975,GO:0034219,GO:0036094,GO:0042597,GO:0042732,GO:0044238,GO:0044281,GO:0044464,GO:0048029,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005766 290.0
HFD3_k127_6547496_19 Oxidoreductase molybdopterin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006566 271.0
HFD3_k127_6547496_2 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005713 616.0
HFD3_k127_6547496_20 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000004058 231.0
HFD3_k127_6547496_21 Belongs to the NiCoT transporter (TC 2.A.52) family K07241 - - 0.000000000000000000000000000000000000000000000000000000000006236 222.0
HFD3_k127_6547496_22 Domain of unknown function (DUF427) - - - 0.000000000000000000000000000000000000000000000000000000002117 205.0
HFD3_k127_6547496_23 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07667 - - 0.00000000000000000000000000000000000000000000000000000009736 205.0
HFD3_k127_6547496_24 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K00177 - 1.2.7.1,1.2.7.3 0.000000000000000000000000000000000000000000007774 177.0
HFD3_k127_6547496_25 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000001667 175.0
HFD3_k127_6547496_26 Protein of unknown function (DUF1440) - - - 0.000000000000000000000000000007004 124.0
HFD3_k127_6547496_27 Aminoacyl-tRNA editing domain K19055 - - 0.000000000000000000000113 104.0
HFD3_k127_6547496_28 Belongs to the Fur family K03711,K09825 - - 0.000000000000000000008264 103.0
HFD3_k127_6547496_29 COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms - - - 0.0000000000000000000262 101.0
HFD3_k127_6547496_3 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531,K01537,K12952 - 3.6.3.2,3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000644 611.0
HFD3_k127_6547496_30 4Fe-4S binding domain K00176 - 1.2.7.3 0.0000000000000000001846 91.0
HFD3_k127_6547496_31 COG2017 Galactose mutarotase and related enzymes K01785 - 5.1.3.3 0.0000000000000000004039 98.0
HFD3_k127_6547496_32 - - - - 0.0000000000000000418 85.0
HFD3_k127_6547496_34 - - - - 0.00000000000355 79.0
HFD3_k127_6547496_35 Belongs to the universal stress protein A family - - - 0.0000000001432 71.0
HFD3_k127_6547496_36 His Kinase A (phosphoacceptor) domain - - - 0.0000003779 53.0
HFD3_k127_6547496_37 - - - - 0.0001375 53.0
HFD3_k127_6547496_4 Belongs to the xylose isomerase family K01805 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575 5.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006117 585.0
HFD3_k127_6547496_5 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006414 583.0
HFD3_k127_6547496_6 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006943 557.0
HFD3_k127_6547496_7 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 548.0
HFD3_k127_6547496_8 Xaa-Pro aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 509.0
HFD3_k127_6547496_9 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005163 484.0
HFD3_k127_6554673_0 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 4.251e-206 677.0
HFD3_k127_6554673_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009541 583.0
HFD3_k127_6554673_10 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000002083 235.0
HFD3_k127_6554673_11 Bacterial transferase hexapeptide - - - 0.000000000000000000000000000000000000000000000000002631 195.0
HFD3_k127_6554673_12 Protein of unknown function (DUF3048) C-terminal domain - - - 0.0000000000000000000000000000000000000000000000002494 195.0
HFD3_k127_6554673_13 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000003738 179.0
HFD3_k127_6554673_14 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000001148 147.0
HFD3_k127_6554673_15 Polysaccharide deacetylase K22278 - 3.5.1.104 0.000000000000000000000000002976 128.0
HFD3_k127_6554673_16 Double zinc ribbon - - - 0.00000000000000000000001879 108.0
HFD3_k127_6554673_17 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000006831 109.0
HFD3_k127_6554673_18 Putative lumazine-binding - - - 0.0000000000000000006631 94.0
HFD3_k127_6554673_19 transferase activity, transferring glycosyl groups - - - 0.0000000000000008137 90.0
HFD3_k127_6554673_2 MreB/Mbl protein K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004595 452.0
HFD3_k127_6554673_20 Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway K03525 - 2.7.1.33 0.000000000006188 79.0
HFD3_k127_6554673_21 Glycosyl transferases group 1 - - - 0.00000000007843 76.0
HFD3_k127_6554673_22 O-antigen - - - 0.0000003675 63.0
HFD3_k127_6554673_23 CAAX protease self-immunity K07052 - - 0.000008651 57.0
HFD3_k127_6554673_3 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009673 376.0
HFD3_k127_6554673_4 PFAM UDP-glucose GDP-mannose dehydrogenase K02472 - 1.1.1.336 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 374.0
HFD3_k127_6554673_5 aromatic amino acid beta-eliminating lyase threonine aldolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000846 355.0
HFD3_k127_6554673_6 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 307.0
HFD3_k127_6554673_7 PFAM Glycosyl transferase family 2 K16557 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002434 268.0
HFD3_k127_6554673_8 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000001298 251.0
HFD3_k127_6554673_9 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000002388 248.0
HFD3_k127_6601775_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 376.0
HFD3_k127_6601775_1 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000001187 248.0
HFD3_k127_6601775_2 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000007846 66.0
HFD3_k127_6601775_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.00001109 55.0
HFD3_k127_6765536_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008043 479.0
HFD3_k127_6765536_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007857 369.0
HFD3_k127_6765536_2 Pyridine nucleotide-disulphide oxidoreductase K07222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001804 258.0
HFD3_k127_6765536_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000003389 151.0
HFD3_k127_6765536_4 Modulates RecA activity K03565 - - 0.000000000000001087 84.0
HFD3_k127_6765536_5 L-lysine 6-monooxygenase (NADPH-requiring) K07222 - - 0.00001774 47.0
HFD3_k127_6866134_0 ATPase associated with various cellular activities, AAA_5 K03696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006799 250.0
HFD3_k127_6866134_1 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001138 241.0
HFD3_k127_6866134_2 PFAM NUDIX hydrolase - - - 0.000000000000000000000001108 111.0
HFD3_k127_6866134_3 - - - - 0.000004726 55.0
HFD3_k127_6996865_0 Anticodon-binding domain of tRNA K01870 - 6.1.1.5 0.0 1094.0
HFD3_k127_6996865_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 481.0
HFD3_k127_6996865_10 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000001208 191.0
HFD3_k127_6996865_11 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000005754 187.0
HFD3_k127_6996865_12 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000009277 190.0
HFD3_k127_6996865_13 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000001995 163.0
HFD3_k127_6996865_14 cell envelope-related transcriptional attenuator - - - 0.0000000000000000000000000000000000000007002 169.0
HFD3_k127_6996865_15 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000001081 146.0
HFD3_k127_6996865_16 Belongs to the glycosyl hydrolase 3 family - - - 0.00000000000000000000000000000000003593 149.0
HFD3_k127_6996865_17 NUBPL iron-transfer P-loop NTPase K02282 - - 0.0000000000000000000000000000001876 143.0
HFD3_k127_6996865_18 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000003686 119.0
HFD3_k127_6996865_19 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963,K03111,K15125 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000002184 107.0
HFD3_k127_6996865_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007465 427.0
HFD3_k127_6996865_20 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000009649 105.0
HFD3_k127_6996865_21 RNA methyltransferase, RsmD family K08316 - 2.1.1.171 0.000000000000000001242 88.0
HFD3_k127_6996865_22 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000001275 97.0
HFD3_k127_6996865_23 Protein conserved in bacteria - - - 0.00000596 55.0
HFD3_k127_6996865_24 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07659 - - 0.000006985 59.0
HFD3_k127_6996865_25 Ribosomal L28 family K02902 - - 0.00002967 53.0
HFD3_k127_6996865_26 Antibiotic biosynthesis monooxygenase - - - 0.0007768 49.0
HFD3_k127_6996865_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008034 344.0
HFD3_k127_6996865_4 PFAM Dak phosphatase K07030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 349.0
HFD3_k127_6996865_5 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 306.0
HFD3_k127_6996865_6 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002495 291.0
HFD3_k127_6996865_7 calcium, potassium:sodium antiporter activity K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002517 286.0
HFD3_k127_6996865_8 Thermolysin metallopeptidase, alpha-helical domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002954 264.0
HFD3_k127_6996865_9 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000001158 212.0
HFD3_k127_7013376_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 441.0
HFD3_k127_7013376_1 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 304.0
HFD3_k127_7014924_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01652 - 2.2.1.6 3.777e-197 630.0
HFD3_k127_7014924_1 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 614.0
HFD3_k127_7014924_11 Short C-terminal domain - - - 0.0000000001746 64.0
HFD3_k127_7014924_12 YCII-related domain - - - 0.000000155 57.0
HFD3_k127_7014924_2 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001289 232.0
HFD3_k127_7014924_3 Belongs to the UPF0173 family - - - 0.0000000000000000000000000000000000000000000000000000000000000003962 228.0
HFD3_k127_7014924_4 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000003695 217.0
HFD3_k127_7014924_5 signal transduction protein containing a membrane domain an EAL and a GGDEF domain K21023 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000002643 220.0
HFD3_k127_7014924_6 Molybdopterin converting factor subunit K03635,K21142 - 2.8.1.12 0.00000000000000000000000000000000000000000001045 180.0
HFD3_k127_7014924_7 Appr-1'-p processing enzyme - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000004977 160.0
HFD3_k127_7014924_8 O-methyltransferase - - - 0.00000000000000000000000000000000004514 144.0
HFD3_k127_7014924_9 Galactose oxidase, central domain - - - 0.000000000000000000002138 107.0
HFD3_k127_7034209_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate - - - 0.0 1303.0
HFD3_k127_7034209_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 357.0
HFD3_k127_7034209_10 Domain of unknown function (DUF4342) - - - 0.0000000000000000003403 96.0
HFD3_k127_7034209_11 - - - - 0.00000000000001168 84.0
HFD3_k127_7034209_12 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins - - - 0.0000000007193 71.0
HFD3_k127_7034209_14 - - - - 0.000001215 57.0
HFD3_k127_7034209_2 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005727 332.0
HFD3_k127_7034209_3 deoxyhypusine monooxygenase activity K01932 - - 0.00000000000000000000000000000000000000000000000000000000000000005037 253.0
HFD3_k127_7034209_4 Truncated hemoglobins K06886 - - 0.000000000000000000000000000000000000000000000000000000000000001861 220.0
HFD3_k127_7034209_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000001646 223.0
HFD3_k127_7034209_6 response regulator K02479 - - 0.0000000000000000000000000000000000000000000000000000006572 202.0
HFD3_k127_7034209_7 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.00000000000000000000000000000006095 137.0
HFD3_k127_7034209_8 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.00000000000000000000008488 103.0
HFD3_k127_7034209_9 Serine aminopeptidase, S33 - - - 0.000000000000000000002937 108.0
HFD3_k127_7085966_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 537.0
HFD3_k127_7085966_1 PFAM peptidase S58, DmpA K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 478.0
HFD3_k127_7085966_10 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001245 248.0
HFD3_k127_7085966_11 Glycosyl hydrolases family 25 K07273 - - 0.00000000000000000000000000000000000000353 158.0
HFD3_k127_7085966_12 Pfam:Pyridox_oxidase - - - 0.000000000000000000000001344 110.0
HFD3_k127_7085966_13 flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase - - - 0.00000000000000000000521 103.0
HFD3_k127_7085966_14 - - - - 0.0000000000001473 77.0
HFD3_k127_7085966_15 membrane protein (DUF2078) K08982 - - 0.000001661 55.0
HFD3_k127_7085966_2 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 482.0
HFD3_k127_7085966_3 Belongs to the amidase family K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 415.0
HFD3_k127_7085966_4 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 392.0
HFD3_k127_7085966_5 Belongs to the long-chain O-acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004653 399.0
HFD3_k127_7085966_6 amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005889 367.0
HFD3_k127_7085966_7 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002728 286.0
HFD3_k127_7085966_8 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002908 277.0
HFD3_k127_7085966_9 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001272 250.0
HFD3_k127_7196890_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 485.0
HFD3_k127_7196890_1 Berberine and berberine like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008628 381.0
HFD3_k127_7196890_10 - K06197 - - 0.0000000000000000387 84.0
HFD3_k127_7196890_11 Cupin - - - 0.00000000000000008362 93.0
HFD3_k127_7196890_12 positive regulation of macromolecule biosynthetic process K03970,K03973 - - 0.000000000008377 75.0
HFD3_k127_7196890_13 - - - - 0.000004857 57.0
HFD3_k127_7196890_14 Phosphotransferase enzyme family - - - 0.0009013 51.0
HFD3_k127_7196890_2 Glutamate decarboxylase and related PLP-dependent K01580 - 4.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 353.0
HFD3_k127_7196890_3 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 306.0
HFD3_k127_7196890_4 COG0604 NADPH quinone reductase and related Zn-dependent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 301.0
HFD3_k127_7196890_5 Putative sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004482 278.0
HFD3_k127_7196890_6 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000001631 208.0
HFD3_k127_7196890_7 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.000000000000000000000000000000000000000000000000000000002456 214.0
HFD3_k127_7196890_8 Flavodoxin domain K00230 - 1.3.5.3 0.00000000000000000000000000000000000000000000009133 175.0
HFD3_k127_7196890_9 glyoxalase III activity - - - 0.000000000000000000000000000000003996 132.0
HFD3_k127_7216627_0 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 8.023e-194 617.0
HFD3_k127_7216627_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006598 447.0
HFD3_k127_7216627_10 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000007649 219.0
HFD3_k127_7216627_11 Protein tyrosine kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000002858 224.0
HFD3_k127_7216627_12 B12- binding domain protein K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000547 185.0
HFD3_k127_7216627_13 Methylmalonyl-CoA mutase K01848,K11942 - 5.4.99.13,5.4.99.2 0.000000000000000000000000000000000005287 140.0
HFD3_k127_7216627_14 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000254 127.0
HFD3_k127_7216627_15 belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000003504 124.0
HFD3_k127_7216627_16 polysaccharide deacetylase - - - 0.00000000000000000000000000005338 130.0
HFD3_k127_7216627_17 lactoylglutathione lyase activity - - - 0.0000000000000000000000000004107 123.0
HFD3_k127_7216627_18 Zincin-like metallopeptidase - - - 0.000000000000000000000000001303 118.0
HFD3_k127_7216627_19 Right handed beta helix region - - - 0.00000000000000001626 94.0
HFD3_k127_7216627_2 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 467.0
HFD3_k127_7216627_20 helix_turn_helix, Arsenical Resistance Operon Repressor K22042 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000832 83.0
HFD3_k127_7216627_22 Belongs to the 'phage' integrase family - - - 0.000000000000009259 81.0
HFD3_k127_7216627_23 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000002955 71.0
HFD3_k127_7216627_3 Drug exporters of the RND superfamily K06994,K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006919 431.0
HFD3_k127_7216627_4 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001297 289.0
HFD3_k127_7216627_5 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005735 282.0
HFD3_k127_7216627_6 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007706 287.0
HFD3_k127_7216627_7 Dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000001576 271.0
HFD3_k127_7216627_8 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000002022 257.0
HFD3_k127_7216627_9 TIGRFAM LAO AO transport system ATPase K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000292 263.0
HFD3_k127_7217685_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 575.0
HFD3_k127_7217685_1 Myo-inositol-1-phosphate synthase K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 479.0
HFD3_k127_7217685_10 DNA-binding transcription factor activity K03892 - - 0.00000000001873 69.0
HFD3_k127_7217685_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00003883 50.0
HFD3_k127_7217685_2 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 459.0
HFD3_k127_7217685_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006125 342.0
HFD3_k127_7217685_4 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006676 295.0
HFD3_k127_7217685_5 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002098 257.0
HFD3_k127_7217685_6 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000003835 185.0
HFD3_k127_7217685_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000001877 108.0
HFD3_k127_7217685_8 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000001995 89.0
HFD3_k127_7217685_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000008141 87.0
HFD3_k127_7220902_0 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005233 263.0
HFD3_k127_7220902_1 Carboxylate--amine ligase - - - 0.00000000000000000000000000000000000000000002252 176.0
HFD3_k127_7220902_2 PFAM DeoC LacD family aldolase K11645 - 4.1.2.13 0.000000000000000000000000000000000002494 149.0
HFD3_k127_7220902_3 Tellurite resistance protein TerB - - - 0.00000000000000000000000000000000002003 143.0
HFD3_k127_7220902_4 - - - - 0.00000000002627 67.0
HFD3_k127_7220902_5 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676,K18917 - 1.20.4.3 0.000002217 58.0
HFD3_k127_7224542_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005485 604.0
HFD3_k127_7224542_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 429.0
HFD3_k127_7224542_10 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.0000000000000000000000000000000000000001776 163.0
HFD3_k127_7224542_11 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon K03709 - - 0.0000000000000000000000000000000006225 143.0
HFD3_k127_7224542_13 Endonuclease/Exonuclease/phosphatase family K18764 - 3.1.13.4 0.00000000000000000000000001029 119.0
HFD3_k127_7224542_14 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000001922 107.0
HFD3_k127_7224542_15 transcriptional regulator K03892 - - 0.0000000000000000003408 91.0
HFD3_k127_7224542_16 - - - - 0.000000003915 64.0
HFD3_k127_7224542_2 PFAM phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 349.0
HFD3_k127_7224542_3 Methyltransferase type 11 K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006683 314.0
HFD3_k127_7224542_4 Two component transcriptional regulator, winged helix family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004931 256.0
HFD3_k127_7224542_5 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000005055 243.0
HFD3_k127_7224542_6 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768,K03320 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000001262 218.0
HFD3_k127_7224542_7 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000077 194.0
HFD3_k127_7224542_8 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000003361 198.0
HFD3_k127_7224542_9 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000009351 164.0
HFD3_k127_7280297_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 559.0
HFD3_k127_7280297_1 TrkA-N domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 455.0
HFD3_k127_7280297_10 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000002026 195.0
HFD3_k127_7280297_11 PFAM YbaK prolyl-tRNA synthetase associated region - - - 0.00000000000000000000000000000000000000002854 163.0
HFD3_k127_7280297_12 Belongs to the N(4) N(6)-methyltransferase family - - - 0.00000000000000000000000000000000000007923 153.0
HFD3_k127_7280297_13 lysozyme - - - 0.0000000000000000000000000000000000008578 155.0
HFD3_k127_7280297_14 NADP transhydrogenase K00324 - 1.6.1.2 0.000000000000000000000000000001603 138.0
HFD3_k127_7280297_15 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000002168 126.0
HFD3_k127_7280297_16 Domain of unknown function (DUF4395) - - - 0.000000000001934 75.0
HFD3_k127_7280297_2 PFAM alanine dehydrogenase PNT domain protein K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 419.0
HFD3_k127_7280297_3 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 332.0
HFD3_k127_7280297_4 Rhodanese Homology Domain K01011 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000662 281.0
HFD3_k127_7280297_5 Threonyl alanyl tRNA synthetase SAD K01872,K07050 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000003791 260.0
HFD3_k127_7280297_6 Glycosyl transferase, family 2 K00786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008269 251.0
HFD3_k127_7280297_7 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000003459 251.0
HFD3_k127_7280297_8 D-alanyl-D-alanine carboxypeptidase K07260 - 3.4.17.14 0.0000000000000000000000000000000000000000000000000000000000000001354 237.0
HFD3_k127_7280297_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000001083 198.0
HFD3_k127_7286938_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005662 412.0
HFD3_k127_7286938_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007521 396.0
HFD3_k127_7286938_10 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000001057 197.0
HFD3_k127_7286938_11 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000000002184 192.0
HFD3_k127_7286938_12 Forms part of the polypeptide exit tunnel K02926 - - 0.000000000000000000000000000000000000000000000000000005557 195.0
HFD3_k127_7286938_13 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000005501 189.0
HFD3_k127_7286938_14 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000002159 181.0
HFD3_k127_7286938_15 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000001592 162.0
HFD3_k127_7286938_16 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000000001967 153.0
HFD3_k127_7286938_17 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000001774 151.0
HFD3_k127_7286938_18 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0008150,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000003521 138.0
HFD3_k127_7286938_19 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.000000000000000000000000000000003118 129.0
HFD3_k127_7286938_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006038 314.0
HFD3_k127_7286938_20 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000003396 119.0
HFD3_k127_7286938_21 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000002327 111.0
HFD3_k127_7286938_22 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000001207 110.0
HFD3_k127_7286938_23 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000003229 104.0
HFD3_k127_7286938_24 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000106 96.0
HFD3_k127_7286938_25 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000143 85.0
HFD3_k127_7286938_26 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000001986 71.0
HFD3_k127_7286938_27 DNA binding - - - 0.000000002332 68.0
HFD3_k127_7286938_28 Ribosomal protein L30p/L7e K02907 - - 0.00000000401 62.0
HFD3_k127_7286938_29 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00014 47.0
HFD3_k127_7286938_3 Methionine aminopeptidase K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004646 291.0
HFD3_k127_7286938_4 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007999 271.0
HFD3_k127_7286938_5 Ribosomal protein S3, C-terminal domain K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000004248 269.0
HFD3_k127_7286938_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000006389 256.0
HFD3_k127_7286938_7 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002429 242.0
HFD3_k127_7286938_8 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000008602 217.0
HFD3_k127_7286938_9 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000002537 214.0
HFD3_k127_7289127_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000561 361.0
HFD3_k127_7289127_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000004468 252.0
HFD3_k127_7289127_10 - - - - 0.00000005988 66.0
HFD3_k127_7289127_11 Carbohydrate kinase - - - 0.0001567 54.0
HFD3_k127_7289127_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000002101 211.0
HFD3_k127_7289127_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000001502 215.0
HFD3_k127_7289127_4 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000002063 198.0
HFD3_k127_7289127_5 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.000000000000000000000000000000000000000005065 162.0
HFD3_k127_7289127_6 PFAM Uncharacterised P-loop hydrolase UPF0079 K06925 - - 0.0000000000000000000000000000000008947 140.0
HFD3_k127_7289127_7 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000002451 113.0
HFD3_k127_7289127_8 Glycoprotease family - - - 0.0000000000002281 81.0
HFD3_k127_7289127_9 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000004529 62.0
HFD3_k127_7305770_0 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 557.0
HFD3_k127_7305770_1 N-terminal double-glycine peptidase domain K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000942 518.0
HFD3_k127_7305770_11 AhpC/TSA antioxidant enzyme - - - 0.00000000001318 74.0
HFD3_k127_7305770_2 Aminotransferase class-III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 474.0
HFD3_k127_7305770_3 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 462.0
HFD3_k127_7305770_4 NMT1/THI5 like K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 420.0
HFD3_k127_7305770_5 ABC transporter K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 321.0
HFD3_k127_7305770_6 Lanthionine synthetase C-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001017 237.0
HFD3_k127_7305770_7 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000000009066 190.0
HFD3_k127_7305770_8 inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000009206 205.0
HFD3_k127_7305770_9 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000002491 157.0
HFD3_k127_7452293_0 Fructose-bisphosphate aldolase class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003564 441.0
HFD3_k127_7452293_1 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005008 304.0
HFD3_k127_7452293_2 Choline/ethanolamine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000001714 231.0
HFD3_k127_7452293_3 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000002296 201.0
HFD3_k127_7452293_4 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000004725 133.0
HFD3_k127_7452293_5 RDD family - - - 0.000000001913 66.0
HFD3_k127_7452293_6 - - - - 0.000000002025 65.0
HFD3_k127_7452293_7 - - - - 0.00002499 52.0
HFD3_k127_7464422_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 4.476e-219 707.0
HFD3_k127_7464422_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 483.0
HFD3_k127_7464422_10 GTP binding - - - 0.000000000000000000000000004686 123.0
HFD3_k127_7464422_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000002215 113.0
HFD3_k127_7464422_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000002443 102.0
HFD3_k127_7464422_13 4Fe-4S dicluster domain K00338 - 1.6.5.3 0.000000000001049 77.0
HFD3_k127_7464422_2 TIGRFAM fructose-1,6-bisphosphatase, class II K02446 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 397.0
HFD3_k127_7464422_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 360.0
HFD3_k127_7464422_4 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008496 315.0
HFD3_k127_7464422_5 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007817 317.0
HFD3_k127_7464422_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003324 287.0
HFD3_k127_7464422_7 Belongs to the peptidase S51 family K05995 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.13.21 0.0000000000000000000000000000000000000000000000000000000000000002499 228.0
HFD3_k127_7464422_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000003324 199.0
HFD3_k127_7464422_9 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950,K13940 - 2.7.6.3,4.1.2.25 0.0000000000000000000000000007281 128.0
HFD3_k127_7465466_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.419e-289 912.0
HFD3_k127_7465466_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 4.844e-271 867.0
HFD3_k127_7465466_10 ParB-like nuclease domain K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004765 258.0
HFD3_k127_7465466_11 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000004578 248.0
HFD3_k127_7465466_12 GyrI-like small molecule binding domain - - - 0.00000000000000000000000000000000000000000000000000000001905 205.0
HFD3_k127_7465466_13 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000689 178.0
HFD3_k127_7465466_14 DUF218 domain - - - 0.000000000000000000000000000000000000000008776 162.0
HFD3_k127_7465466_15 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation K09811 - - 0.0000000000000000000000000000000000000003141 160.0
HFD3_k127_7465466_16 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000128 134.0
HFD3_k127_7465466_17 acetyltransferase - - - 0.00000000000000000000000009598 119.0
HFD3_k127_7465466_18 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000003146 112.0
HFD3_k127_7465466_19 thiolester hydrolase activity K03186 - 2.5.1.129 0.000000000000000000000003722 110.0
HFD3_k127_7465466_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 1.785e-268 841.0
HFD3_k127_7465466_20 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.0000000000000373 82.0
HFD3_k127_7465466_21 DNA alkylation repair enzyme - - - 0.000002879 59.0
HFD3_k127_7465466_22 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.00001455 56.0
HFD3_k127_7465466_3 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 532.0
HFD3_k127_7465466_4 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 409.0
HFD3_k127_7465466_5 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 388.0
HFD3_k127_7465466_6 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 335.0
HFD3_k127_7465466_7 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 300.0
HFD3_k127_7465466_8 TIGRFAM Cell division ATP-binding protein FtsE K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009647 269.0
HFD3_k127_7465466_9 Belongs to the peptidase S41A family K03797 GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016787,GO:0019538,GO:0023052,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000001404 277.0
HFD3_k127_7468031_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1170.0
HFD3_k127_7468031_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006283 586.0
HFD3_k127_7468031_10 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 398.0
HFD3_k127_7468031_11 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 379.0
HFD3_k127_7468031_12 Belongs to the GARS family K01945,K11788 GO:0008150,GO:0040007 6.3.3.1,6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 338.0
HFD3_k127_7468031_13 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 333.0
HFD3_k127_7468031_14 SAICAR synthetase K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009849 312.0
HFD3_k127_7468031_15 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 296.0
HFD3_k127_7468031_16 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 294.0
HFD3_k127_7468031_17 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008675 266.0
HFD3_k127_7468031_18 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000001259 234.0
HFD3_k127_7468031_19 ABC-type dipeptide oligopeptide nickel transport K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000115 236.0
HFD3_k127_7468031_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 561.0
HFD3_k127_7468031_20 ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000000000000000007228 210.0
HFD3_k127_7468031_21 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000016 168.0
HFD3_k127_7468031_22 Rossmann-like domain - - - 0.00000000000000000000000000000000000000000003731 173.0
HFD3_k127_7468031_23 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000001728 171.0
HFD3_k127_7468031_24 NUDIX domain - - - 0.000000000000000000000000000000001269 139.0
HFD3_k127_7468031_25 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000000000000000000000004139 127.0
HFD3_k127_7468031_26 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000006901 119.0
HFD3_k127_7468031_27 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000009374 78.0
HFD3_k127_7468031_3 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 462.0
HFD3_k127_7468031_4 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 451.0
HFD3_k127_7468031_5 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 434.0
HFD3_k127_7468031_6 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 423.0
HFD3_k127_7468031_7 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 419.0
HFD3_k127_7468031_8 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 409.0
HFD3_k127_7468031_9 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 428.0
HFD3_k127_7503310_0 PIN domain K07064 - - 0.000000000000000000000000000000001485 133.0
HFD3_k127_7503310_1 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.000000000000000000000002317 110.0
HFD3_k127_7503310_2 COG COG0210 Superfamily I DNA and RNA helicases DNA replication recombination and repair K03657 - 3.6.4.12 0.000000000001169 72.0
HFD3_k127_7503310_3 positive regulation of growth - - - 0.000000002678 61.0
HFD3_k127_7503310_4 SnoaL-like domain - - - 0.00000005626 54.0
HFD3_k127_7575561_0 DEAD DEAH box helicase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009799 524.0
HFD3_k127_7575561_1 hydrolase activity, acting on ester bonds K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 503.0
HFD3_k127_7575561_2 DNA glycosylase K03649 - 3.2.2.28 0.0000000000000000000000000000000000000000000000000000000000000000001032 236.0
HFD3_k127_7575561_3 PFAM Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000008618 187.0
HFD3_k127_7575561_4 PFAM Bacterial regulatory protein, arsR family - - - 0.000000000000000000000000000000000000000006141 157.0
HFD3_k127_7575561_5 F420H(2)-dependent quinone reductase - - - 0.00000000000000000000000000004068 121.0
HFD3_k127_7575561_6 - - - - 0.0002199 52.0
HFD3_k127_7597361_0 Beta-eliminating lyase K01667 - 4.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 612.0
HFD3_k127_7597361_1 Putative neutral zinc metallopeptidase K07054 GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002395 267.0
HFD3_k127_7597361_2 3-methyladenine DNA glycosylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001228 256.0
HFD3_k127_7597361_3 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000002027 244.0
HFD3_k127_7597361_4 Lytic transglycolase - - - 0.0000000000000000001007 98.0
HFD3_k127_7597361_5 TfoX N-terminal domain - - - 0.00000000000115 73.0
HFD3_k127_760502_0 Acyl- CoA dehydrogenase type 2 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 562.0
HFD3_k127_760502_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 395.0
HFD3_k127_760502_10 F420-dependent oxidoreductase - - - 0.0000002119 64.0
HFD3_k127_760502_2 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 338.0
HFD3_k127_760502_3 sequence-specific DNA binding K00567,K13529,K15051 - 2.1.1.63,3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000009304 245.0
HFD3_k127_760502_4 EamA-like transporter family - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000006147 243.0
HFD3_k127_760502_5 UbiA prenyltransferase family K02548 GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046428,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 2.5.1.74 0.0000000000000000000000000000000000000000000000000008121 204.0
HFD3_k127_760502_6 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000007371 143.0
HFD3_k127_760502_7 CAAX protease self-immunity K07052 - - 0.0000000000000000000000001807 115.0
HFD3_k127_760502_8 Sodium/hydrogen exchanger family K03316 - - 0.000000000000000000000000233 117.0
HFD3_k127_760502_9 Helix-turn-helix domain - - - 0.000000001519 62.0
HFD3_k127_7624514_0 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000524 196.0
HFD3_k127_7624514_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000001726 83.0
HFD3_k127_7624514_2 PIN domain - - - 0.0000000000002126 79.0
HFD3_k127_7624514_3 Type I restriction-modification system methyltransferase subunit - - - 0.0000002506 61.0
HFD3_k127_7665883_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 447.0
HFD3_k127_7665883_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 293.0
HFD3_k127_7665883_2 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008685 273.0
HFD3_k127_7665883_3 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000002271 237.0
HFD3_k127_7665883_4 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000004716 213.0
HFD3_k127_7665883_5 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000007509 203.0
HFD3_k127_776216_0 FeS assembly protein SufB K09014 - - 4.34e-207 655.0
HFD3_k127_776216_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 368.0
HFD3_k127_776216_10 pfam nudix - - - 0.0000000000000000000000000000000000000000000006312 174.0
HFD3_k127_776216_11 Protein of unknown function (DUF421) - - - 0.000000000000000000000000000000000000000002135 162.0
HFD3_k127_776216_12 PFAM OsmC family protein K04063 - - 0.0000000000000000000000000000000000000007227 152.0
HFD3_k127_776216_13 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.000000000000000000000000000000000006531 150.0
HFD3_k127_776216_14 Histidine kinase - - - 0.000000000000000000000000000000000163 151.0
HFD3_k127_776216_15 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000002982 139.0
HFD3_k127_776216_17 SnoaL-like domain - - - 0.00000000000001414 85.0
HFD3_k127_776216_18 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases K05710 - - 0.0000000000002116 79.0
HFD3_k127_776216_19 Protein tyrosine kinase - - - 0.0000000000003096 76.0
HFD3_k127_776216_2 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 327.0
HFD3_k127_776216_3 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 312.0
HFD3_k127_776216_4 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000116 284.0
HFD3_k127_776216_5 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000002207 253.0
HFD3_k127_776216_6 - - - - 0.00000000000000000000000000000000000000000000000000000005591 199.0
HFD3_k127_776216_7 guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000008001 196.0
HFD3_k127_776216_8 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000001903 196.0
HFD3_k127_776216_9 Uncharacterized protein family (UPF0051) K07033,K09015 - - 0.0000000000000000000000000000000000000000000000003672 194.0
HFD3_k127_812153_0 PFAM Mandelate racemase muconate lactonizing K01684 - 4.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 568.0
HFD3_k127_812153_1 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005709 435.0
HFD3_k127_812153_10 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003304 277.0
HFD3_k127_812153_11 mandelate racemase muconate lactonizing - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001332 284.0
HFD3_k127_812153_12 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008064 286.0
HFD3_k127_812153_13 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001012 244.0
HFD3_k127_812153_14 dihydrodipicolinate reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000212 245.0
HFD3_k127_812153_15 ABC transporter K02056,K10554 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000005412 231.0
HFD3_k127_812153_16 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000003224 223.0
HFD3_k127_812153_17 methionine synthase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000009332 220.0
HFD3_k127_812153_18 cobalamin binding - - - 0.000000000000000000000000000000000000000000000000000000000009671 217.0
HFD3_k127_812153_19 metal-dependent hydrolase with the TIM-barrel fold K07048 - - 0.00000000000000000000000000000000000000000000000000000001325 212.0
HFD3_k127_812153_2 Domain of unknown function (DUF4445) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 422.0
HFD3_k127_812153_20 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000001761 215.0
HFD3_k127_812153_21 Belongs to the binding-protein-dependent transport system permease family K10440,K17206 - - 0.00000000000000000000000000000000000000000000000000003747 202.0
HFD3_k127_812153_22 Enoyl-(Acyl carrier protein) reductase K00059,K00065 - 1.1.1.100,1.1.1.127 0.00000000000000000000000000000000000000000000000001279 196.0
HFD3_k127_812153_23 Periplasmic binding protein domain K10439 - - 0.0000000000000000000000000000000000000000000000001971 190.0
HFD3_k127_812153_24 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.00000000000000000000000000000000000000000000000998 187.0
HFD3_k127_812153_25 alcohol dehydrogenase K00153 - 1.1.1.306 0.0000000000000000000000000000000000000000000000621 182.0
HFD3_k127_812153_26 KR domain - - - 0.0000000000000000000000000000000000000000000002785 176.0
HFD3_k127_812153_27 Binding-protein-dependent transport system inner membrane component K02026,K10238 - - 0.000000000000000000000000000000000000000000000491 181.0
HFD3_k127_812153_28 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000001783 176.0
HFD3_k127_812153_29 short-chain dehydrogenase - - - 0.000000000000000000000000000000000000000002097 166.0
HFD3_k127_812153_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004255 394.0
HFD3_k127_812153_30 PFAM short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000194 154.0
HFD3_k127_812153_31 Protein of unknown function (DUF1638) - - - 0.000000000000000000000000000000000001359 151.0
HFD3_k127_812153_32 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000003466 142.0
HFD3_k127_812153_33 Bacterial extracellular solute-binding protein - - - 0.00000000000000000000000000000008976 140.0
HFD3_k127_812153_34 (E1) component, eukaryotic type, alpha subunit K21416 - - 0.0000000000000000000000000000005627 132.0
HFD3_k127_812153_35 Lipocalin-like domain - - - 0.000000000000000000000000001329 126.0
HFD3_k127_812153_36 L-rhamnose mutarotase K03534 - 5.1.3.32 0.00000000000000000000000002628 117.0
HFD3_k127_812153_37 Endoribonuclease L-PSP - - - 0.00000000000000000000000003211 112.0
HFD3_k127_812153_38 Converts the aldose L-fucose into the corresponding ketose L-fuculose K01804 - 5.3.1.4 0.00000000000000000000002138 115.0
HFD3_k127_812153_39 Periplasmic binding protein domain K02058 - - 0.00000000000000000003341 106.0
HFD3_k127_812153_4 Uroporphyrinogen decarboxylase (URO-D) K01599,K14080 - 2.1.1.246,4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 369.0
HFD3_k127_812153_40 Involved in the anomeric conversion of L-rhamnose K03534 - 5.1.3.32 0.000000000000000004119 87.0
HFD3_k127_812153_41 Pfam:DUF718 K03534 - 5.1.3.32 0.000000006648 65.0
HFD3_k127_812153_5 Aldo/keto reductase family K00064 - 1.1.1.122 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000371 352.0
HFD3_k127_812153_6 helix_turn _helix lactose operon repressor K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 337.0
HFD3_k127_812153_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 303.0
HFD3_k127_812153_8 Belongs to the binding-protein-dependent transport system permease family K10440,K17206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006824 296.0
HFD3_k127_812153_9 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009704 293.0
HFD3_k127_813447_0 Domain of unknown function (DUF4445) - - - 4.589e-266 845.0
HFD3_k127_813447_1 Trimethylamine methyltransferase (MTTB) - - - 8.151e-238 766.0
HFD3_k127_813447_10 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009052 361.0
HFD3_k127_813447_11 Pyridoxal-phosphate dependent enzyme K12339,K21148 - 2.5.1.113,2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 358.0
HFD3_k127_813447_12 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 351.0
HFD3_k127_813447_13 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 335.0
HFD3_k127_813447_14 PFAM TrkA-N domain K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 343.0
HFD3_k127_813447_15 Inosine-uridine preferring nucleoside hydrolase K01239,K01250 - 3.2.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000437 335.0
HFD3_k127_813447_16 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008444 347.0
HFD3_k127_813447_17 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005393 322.0
HFD3_k127_813447_18 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001523 289.0
HFD3_k127_813447_19 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008538 285.0
HFD3_k127_813447_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004613 545.0
HFD3_k127_813447_20 hydratase K18364 - 4.2.1.132,4.2.1.80 0.00000000000000000000000000000000000000000000000000000000000000000001276 242.0
HFD3_k127_813447_21 ATPases associated with a variety of cellular activities K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000009617 235.0
HFD3_k127_813447_22 Protein of unknown function (DUF1638) - - - 0.00000000000000000000000000000000000000000000000000000000000000002786 233.0
HFD3_k127_813447_23 COG0685 5,10-methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000004595 237.0
HFD3_k127_813447_24 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000009165 215.0
HFD3_k127_813447_25 Psort location CytoplasmicMembrane, score 9.49 K02006,K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000007486 204.0
HFD3_k127_813447_26 phosphorelay sensor kinase activity K16923,K18967 - 2.7.7.65 0.00000000000000000000000000000000000000006583 166.0
HFD3_k127_813447_27 Transcriptional regulator - - - 0.0000000000000000000000000000000000000003575 154.0
HFD3_k127_813447_28 Aldehyde oxidase and xanthine dehydrogenase - - - 0.000000000000000000000000000000000000005366 151.0
HFD3_k127_813447_29 helix_turn_helix isocitrate lyase regulation - - - 0.00000000000000000000000000000000000001247 156.0
HFD3_k127_813447_3 Aldehyde dehydrogenase family K00130 - 1.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 494.0
HFD3_k127_813447_30 NifU-like N terminal domain K04488 - - 0.00000000000000000000000000000000000001443 149.0
HFD3_k127_813447_31 Cobalt transport protein K16785 - - 0.000000000000000000000000000000000009173 147.0
HFD3_k127_813447_32 PFAM NUDIX domain - - - 0.00000000000000000000000000000000001236 148.0
HFD3_k127_813447_33 COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms - - - 0.00000000000000000000001254 114.0
HFD3_k127_813447_34 Mov34 MPN PAD-1 family K21140 - 3.13.1.6 0.000000000000000000000324 103.0
HFD3_k127_813447_35 ThiS family K03636 GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.0000000000000000000006285 100.0
HFD3_k127_813447_36 Sigma-70 region 2 K03088 GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.000000000000000000002315 104.0
HFD3_k127_813447_37 Virulence factor - - - 0.00000000000000000001135 104.0
HFD3_k127_813447_38 - - - - 0.0000001777 56.0
HFD3_k127_813447_4 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000481 472.0
HFD3_k127_813447_5 PFAM UBA THIF-type NAD FAD binding protein K21029,K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009402 467.0
HFD3_k127_813447_6 COG1410 Methionine synthase I cobalamin-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 422.0
HFD3_k127_813447_7 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 399.0
HFD3_k127_813447_8 Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds K01666 - 4.1.3.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 397.0
HFD3_k127_813447_9 Prokaryotic acetaldehyde dehydrogenase, dimerisation K04073 - 1.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 386.0
HFD3_k127_864159_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 299.0
HFD3_k127_864159_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000003011 99.0
HFD3_k127_870236_0 RNase_H superfamily - - - 1.664e-290 932.0
HFD3_k127_870236_1 N-terminal domain of (some) glycogen debranching enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007942 563.0
HFD3_k127_870236_10 PFAM glycosyl transferase, family 51 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002528 277.0
HFD3_k127_870236_11 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000229 151.0
HFD3_k127_870236_12 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000001301 127.0
HFD3_k127_870236_13 lactoylglutathione lyase activity - - - 0.000000000000000000000000005187 121.0
HFD3_k127_870236_14 lactoylglutathione lyase activity - - - 0.0000000000000000000000001124 117.0
HFD3_k127_870236_15 - - - - 0.0000000000000000000000006916 108.0
HFD3_k127_870236_16 Histidine kinase - - - 0.000000000000000000000001 121.0
HFD3_k127_870236_17 Methicillin resistance protein - - - 0.0000000000000006752 90.0
HFD3_k127_870236_18 Periplasmic component of the Tol biopolymer transport system - - - 0.000000000000002258 89.0
HFD3_k127_870236_19 PFAM Transglycosylase associated protein - - - 0.00000000000002278 76.0
HFD3_k127_870236_2 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004823 477.0
HFD3_k127_870236_20 exodeoxyribonuclease I activity - - - 0.000000000002184 76.0
HFD3_k127_870236_21 YGGT family - - - 0.000000002596 66.0
HFD3_k127_870236_3 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 460.0
HFD3_k127_870236_4 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 460.0
HFD3_k127_870236_5 Periplasmic binding protein domain K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 379.0
HFD3_k127_870236_6 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 368.0
HFD3_k127_870236_7 Branched-chain amino acid transport system / permease component K10440,K10560 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007867 364.0
HFD3_k127_870236_8 transferase activity, transferring glycosyl groups K21369 - 2.4.1.270 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 353.0
HFD3_k127_870236_9 ABC transporter K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 304.0
HFD3_k127_875099_0 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 540.0
HFD3_k127_875099_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 383.0
HFD3_k127_875099_10 TadE-like protein - - - 0.00001526 54.0
HFD3_k127_875099_11 TadE-like protein - - - 0.0001225 52.0
HFD3_k127_875099_12 Putative Flp pilus-assembly TadE/G-like - - - 0.0002028 54.0
HFD3_k127_875099_2 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000001513 256.0
HFD3_k127_875099_3 Mur ligase family, catalytic domain K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000002458 252.0
HFD3_k127_875099_4 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000003148 216.0
HFD3_k127_875099_5 D-alanyl-D-alanine carboxypeptidase K07260 - 3.4.17.14 0.0000000000000000000000000000000000000000000000000000002214 212.0
HFD3_k127_875099_6 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000002849 184.0
HFD3_k127_875099_7 FR47-like protein - - - 0.0000000000000000009187 96.0
HFD3_k127_875099_8 Histidine kinase - - - 0.000000000000000008195 96.0
HFD3_k127_875099_9 PFAM intradiol ring-cleavage dioxygenase - - - 0.00000003371 58.0
HFD3_k127_886943_0 Lysine-2,3-aminomutase K01843 - 5.4.3.2 1.072e-217 688.0
HFD3_k127_886943_1 PFAM MMPL domain protein K06994 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 597.0
HFD3_k127_886943_2 COG0147 Anthranilate para-aminobenzoate synthases component I K01665 - 2.6.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000988 356.0
HFD3_k127_886943_3 Multicopper oxidase K00368 - 1.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001119 266.0
HFD3_k127_886943_4 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002989 265.0
HFD3_k127_886943_5 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000003086 192.0
HFD3_k127_886943_6 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000007981 150.0
HFD3_k127_886943_7 transcriptional regulator, Rrf2 family K13643 - - 0.000000000003296 73.0
HFD3_k127_886943_8 Protein of unknown function (DUF433) - - - 0.0000003106 59.0
HFD3_k127_89699_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1038.0
HFD3_k127_89699_1 PFAM ABC transporter related K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003781 578.0
HFD3_k127_89699_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000003473 259.0
HFD3_k127_89699_3 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000006836 243.0
HFD3_k127_89699_4 PFAM basic membrane lipoprotein K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000004919 240.0
HFD3_k127_89699_5 Kelch motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000418 243.0
HFD3_k127_89699_6 PFAM basic membrane lipoprotein K07335 - - 0.00000000000000000000000000000000000000000002283 181.0
HFD3_k127_89699_7 CoA-binding protein K06929 - - 0.0000000000000000000000000000000001603 141.0
HFD3_k127_89699_8 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000172 131.0
HFD3_k127_89699_9 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000003429 132.0
HFD3_k127_907445_0 Tetratricopeptide repeat - - - 1.408e-219 721.0
HFD3_k127_907445_1 Glycosyl hydrolase family 1 K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 541.0
HFD3_k127_907445_10 gluconolactonase activity K01053,K02352 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007219 330.0
HFD3_k127_907445_11 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627,K00658,K09699 - 2.3.1.12,2.3.1.168,2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009927 321.0
HFD3_k127_907445_12 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007682 299.0
HFD3_k127_907445_13 metal-dependent hydrolase with the TIM-barrel fold K07048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003009 285.0
HFD3_k127_907445_14 Phosphotriesterase related K07048 GO:0008150,GO:0009888,GO:0009987,GO:0030154,GO:0030855,GO:0032502,GO:0048856,GO:0048869,GO:0060429 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007227 286.0
HFD3_k127_907445_15 transcriptional regulator K02444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000184 266.0
HFD3_k127_907445_16 MlrC C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001696 267.0
HFD3_k127_907445_17 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000006566 245.0
HFD3_k127_907445_18 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000003267 233.0
HFD3_k127_907445_19 (ABC) transporter K10554 - - 0.000000000000000000000000000000000000000000000000000000000000002838 231.0
HFD3_k127_907445_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 484.0
HFD3_k127_907445_20 Branched-chain amino acid transport system / permease component K10440,K10560 - - 0.00000000000000000000000000000000000000000000000000009977 206.0
HFD3_k127_907445_21 KR domain - - - 0.0000000000000000000000000000000000000000000000000002183 199.0
HFD3_k127_907445_22 Binding-protein-dependent transport system inner membrane component K17236 - - 0.0000000000000000000000000000000000000000000000000009125 203.0
HFD3_k127_907445_23 carbohydrate transport K17234 - - 0.000000000000000000000000000000000000000000000000004404 205.0
HFD3_k127_907445_24 Binding-protein-dependent transport system inner membrane component K02025,K10189 - - 0.000000000000000000000000000000000000000000000000009161 191.0
HFD3_k127_907445_25 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.00000000000000000000000000000000000000000000000006436 191.0
HFD3_k127_907445_26 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000001936 180.0
HFD3_k127_907445_27 Enoyl-(Acyl carrier protein) reductase K00046 - 1.1.1.69 0.0000000000000000000000000000000000000002031 160.0
HFD3_k127_907445_28 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000001816 138.0
HFD3_k127_907445_29 Belongs to the globin family - - - 0.00000000000000000000000000000007512 134.0
HFD3_k127_907445_3 mandelate racemase muconate lactonizing K18983 - 5.5.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005611 457.0
HFD3_k127_907445_30 PFAM Neutral alkaline nonlysosomal ceramidase - - - 0.00000000000000000000002154 116.0
HFD3_k127_907445_31 Periplasmic binding protein domain K10439 - - 0.000000000000000000001244 108.0
HFD3_k127_907445_32 Globin - - - 0.000000000000000002288 94.0
HFD3_k127_907445_33 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000002456 81.0
HFD3_k127_907445_34 Molybdopterin binding aldehyde oxidase and xanthine dehydrogenase K16877 - 1.3.99.8 0.0000000002101 74.0
HFD3_k127_907445_35 hydrolase activity, hydrolyzing O-glycosyl compounds K00690,K01187,K01206,K01215,K01226,K17624 - 2.4.1.7,3.2.1.20,3.2.1.51,3.2.1.70,3.2.1.93,3.2.1.97 0.0000000303 67.0
HFD3_k127_907445_36 Periplasmic binding protein domain K10439,K10552 - - 0.000008651 58.0
HFD3_k127_907445_4 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K18983 - 5.5.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 448.0
HFD3_k127_907445_5 transferase K07749,K18702 - 2.8.3.16,2.8.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 419.0
HFD3_k127_907445_6 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 429.0
HFD3_k127_907445_7 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 413.0
HFD3_k127_907445_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007258 384.0
HFD3_k127_907445_9 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005964 368.0
HFD3_k127_916994_0 Flavin containing amine oxidoreductase - - - 2.954e-235 741.0
HFD3_k127_916994_1 Aminotransferase, class I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 454.0
HFD3_k127_916994_10 Abc transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000004812 200.0
HFD3_k127_916994_11 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.00000000000000000000000000000000000000000000001519 185.0
HFD3_k127_916994_12 Belongs to the arginase family K01476 - 3.5.3.1 0.00000000000000000000000000000131 132.0
HFD3_k127_916994_13 Protein of unknown function (DUF4242) - - - 0.000000000000000000000002771 110.0
HFD3_k127_916994_14 PFAM zinc finger, SWIM domain protein - - - 0.0000000000000000000000143 104.0
HFD3_k127_916994_15 AI-2E family transporter - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000000000000000003117 107.0
HFD3_k127_916994_16 Non-essential cell division protein that could be required for efficient cell constriction - - - 0.0002109 53.0
HFD3_k127_916994_2 TIGRFAM phytoene desaturase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 439.0
HFD3_k127_916994_3 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 426.0
HFD3_k127_916994_4 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003738 400.0
HFD3_k127_916994_5 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 347.0
HFD3_k127_916994_6 Tryptophanyl-tRNA synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 340.0
HFD3_k127_916994_7 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000004663 250.0
HFD3_k127_916994_8 Homoserine dehydrogenase K00003,K12524 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.1.1.3,2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000006236 252.0
HFD3_k127_916994_9 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000003288 224.0
HFD3_k127_927354_0 UvrD/REP helicase N-terminal domain K03657,K07465 - 3.6.4.12 3.779e-245 797.0
HFD3_k127_927354_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007894 475.0
HFD3_k127_927354_10 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000000000003678 218.0
HFD3_k127_927354_11 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000007108 232.0
HFD3_k127_927354_12 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000002568 224.0
HFD3_k127_927354_13 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000208 211.0
HFD3_k127_927354_14 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000007319 192.0
HFD3_k127_927354_15 InterPro IPR014922 - - - 0.00000000000000000000000000000000000000000000000002571 187.0
HFD3_k127_927354_16 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000000000000000000000000000000000000000000001181 198.0
HFD3_k127_927354_17 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000002038 157.0
HFD3_k127_927354_18 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000001623 134.0
HFD3_k127_927354_19 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000001479 137.0
HFD3_k127_927354_2 MgsA AAA+ ATPase C terminal K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 431.0
HFD3_k127_927354_20 Belongs to the phosphoglycerate mutase family K22305 - 3.1.3.3 0.000000000000000000000005893 115.0
HFD3_k127_927354_21 Histidine kinase - - - 0.00000000000000000000001495 115.0
HFD3_k127_927354_22 Protein of unknown function (DUF4446) - - - 0.000000000000000005948 93.0
HFD3_k127_927354_23 HAD-hyrolase-like K07025 - - 0.000000000000003136 88.0
HFD3_k127_927354_24 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K19517 - 2.7.1.15,2.7.1.64 0.0000002708 61.0
HFD3_k127_927354_25 helix_turn_helix, Lux Regulon K07684 - - 0.00005332 52.0
HFD3_k127_927354_3 ABC transporter substrate-binding protein K10232 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007333 381.0
HFD3_k127_927354_4 Belongs to the arginase family K01480 - 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006605 369.0
HFD3_k127_927354_5 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009596 346.0
HFD3_k127_927354_6 ATPase associated with various cellular K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006928 305.0
HFD3_k127_927354_7 PFAM aminotransferase class V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009631 328.0
HFD3_k127_927354_8 Zincin-like metallopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003441 261.0
HFD3_k127_927354_9 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region - - - 0.00000000000000000000000000000000000000000000000000000000000000109 248.0
HFD3_k127_930543_0 FAD dependent oxidoreductase central domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006203 601.0
HFD3_k127_930543_1 Asparaginase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005167 606.0
HFD3_k127_930543_10 xanthine dehydrogenase activity K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000002808 239.0
HFD3_k127_930543_11 Transcriptional regulator IclR - - - 0.0000000000000000000000000000000000000000000000000000000000007859 229.0
HFD3_k127_930543_12 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K00087,K03518 - 1.17.1.4,1.2.5.3 0.000000000000000000000000000000000000000000000000003754 189.0
HFD3_k127_930543_13 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000001055 196.0
HFD3_k127_930543_14 Myristoyl transferase K02051 - - 0.000000000000000000000000000000000000000003176 169.0
HFD3_k127_930543_15 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000001283 132.0
HFD3_k127_930543_16 PFAM Major Facilitator Superfamily - - - 0.00000000000001204 87.0
HFD3_k127_930543_17 FCD - - - 0.000001948 58.0
HFD3_k127_930543_18 Putative amidase domain - - - 0.0000595 53.0
HFD3_k127_930543_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 509.0
HFD3_k127_930543_3 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 417.0
HFD3_k127_930543_4 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 357.0
HFD3_k127_930543_5 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006752 334.0
HFD3_k127_930543_6 Electron transfer flavoprotein K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 310.0
HFD3_k127_930543_7 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003645 288.0
HFD3_k127_930543_8 Electron transfer flavoprotein, beta subunit K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009533 260.0
HFD3_k127_930543_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K16049 - 1.13.11.25 0.000000000000000000000000000000000000000000000000000000000000000001446 244.0
HFD3_k127_9353_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 496.0
HFD3_k127_9353_1 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008984 347.0
HFD3_k127_9353_2 COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000006395 239.0
HFD3_k127_9353_3 Periplasmic binding protein domain K10439 - - 0.000000000000000000000000000000000000000000000000000000006507 214.0
HFD3_k127_9353_4 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000178 216.0
HFD3_k127_9353_5 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000237 194.0
HFD3_k127_9353_7 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.00004968 51.0
HFD3_k127_992365_0 competence protein COMEC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 425.0
HFD3_k127_992365_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004983 247.0
HFD3_k127_992365_2 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.0000000000000000000000006594 110.0