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Overview

ID MAG01691
Name HFD3_bin.33
Sample SMP0045
Taxonomy
Kingdom Bacteria
Phylum Eisenbacteria
Class RBG-16-71-46
Order RBG-16-71-46
Family RBG-16-71-46
Genus DATKAB01
Species
Assembly information
Completeness (%) 90.48
Contamination (%) 0.18
GC content (%) 72.0
N50 (bp) 37,452
Genome size (bp) 4,098,739

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3059

Gene name Description KEGG GOs EC E-value Score Sequence
HFD3_k127_1079497_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007526 503.0
HFD3_k127_1079497_1 Adenylosuccinate lyase C-terminus K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 432.0
HFD3_k127_1079497_2 serine-type endopeptidase activity K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000001326 276.0
HFD3_k127_1079497_3 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000000000000005715 201.0
HFD3_k127_1079497_4 Nickel-dependent hydrogenase - - - 0.000000000000000000000000000000000000000003385 180.0
HFD3_k127_1079497_5 Hydrogenase maturation protease - - - 0.0000000000000008993 81.0
HFD3_k127_1079497_6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16785 - - 0.0000000002363 68.0
HFD3_k127_1113519_0 Cytochrome C and Quinol oxidase polypeptide I K15862 - 1.9.3.1 0.0 1196.0
HFD3_k127_1113519_1 Putative metal-binding domain of cation transport ATPase K01533 - 3.6.3.4 4.634e-268 850.0
HFD3_k127_1113519_10 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.00000000000000000000000000000000000000000000000000001473 199.0
HFD3_k127_1113519_11 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000000000000000000000008427 197.0
HFD3_k127_1113519_12 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000008097 207.0
HFD3_k127_1113519_13 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000004664 189.0
HFD3_k127_1113519_14 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000000000000000000001856 177.0
HFD3_k127_1113519_15 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000195 180.0
HFD3_k127_1113519_16 - - - - 0.00000000000000000000000000000003215 145.0
HFD3_k127_1113519_17 PFAM YbaK prolyl-tRNA synthetase associated region K19055 - - 0.000000000000000000000000001507 128.0
HFD3_k127_1113519_18 Transposase - - - 0.000000000000000000000005537 103.0
HFD3_k127_1113519_19 FixH - - - 0.0000000000000000004708 102.0
HFD3_k127_1113519_2 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 1.701e-243 771.0
HFD3_k127_1113519_20 Papain-like cysteine protease AvrRpt2 - - - 0.00000000000000003622 87.0
HFD3_k127_1113519_21 Tetratricopeptide repeat - - - 0.000000000000001302 87.0
HFD3_k127_1113519_22 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000000000004732 83.0
HFD3_k127_1113519_23 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000001407 77.0
HFD3_k127_1113519_24 Transposase K07483 - - 0.00000000007797 67.0
HFD3_k127_1113519_25 Cytochrome oxidase maturation protein cbb3-type - - - 0.00000001144 62.0
HFD3_k127_1113519_26 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.0001305 53.0
HFD3_k127_1113519_3 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007121 530.0
HFD3_k127_1113519_4 ERAP1-like C-terminal domain K01256,K01263 - 3.4.11.14,3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009121 469.0
HFD3_k127_1113519_5 response regulator K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 430.0
HFD3_k127_1113519_6 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006304 350.0
HFD3_k127_1113519_7 Histidine kinase K13598 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000007538 280.0
HFD3_k127_1113519_8 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000008364 238.0
HFD3_k127_1113519_9 Integrase core domain - - - 0.0000000000000000000000000000000000000000000000000000002727 204.0
HFD3_k127_1116678_0 MBOAT, membrane-bound O-acyltransferase family K19294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 501.0
HFD3_k127_1116678_1 - Amino acid transport and metabolism K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 514.0
HFD3_k127_1116678_10 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000004331 221.0
HFD3_k127_1116678_11 Domain of unknown function (DUF3473) - - - 0.00000000000000000000000000000000000000000000000000003303 215.0
HFD3_k127_1116678_12 - - - - 0.0000000000000000000000000000000000000000003706 176.0
HFD3_k127_1116678_13 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000001116 163.0
HFD3_k127_1116678_14 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000000000004756 138.0
HFD3_k127_1116678_15 Glycosyl transferase family 2 - - - 0.000000000000000000000000001388 124.0
HFD3_k127_1116678_16 - - - - 0.000000000000000000000004954 114.0
HFD3_k127_1116678_17 -O-antigen K18814 - - 0.000000000000000000062 104.0
HFD3_k127_1116678_18 membrane - - - 0.0000000000000000001206 105.0
HFD3_k127_1116678_19 O-acyltransferase activity - - - 0.000000000002945 77.0
HFD3_k127_1116678_2 Belongs to the ATP-dependent AMP-binding enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004938 435.0
HFD3_k127_1116678_20 Phosphopantetheine attachment site - - - 0.0000004406 63.0
HFD3_k127_1116678_21 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000002601 60.0
HFD3_k127_1116678_22 Glycosyl transferase family group 2 - - - 0.000003907 60.0
HFD3_k127_1116678_3 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00066 - 1.1.1.132 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 432.0
HFD3_k127_1116678_4 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006063 381.0
HFD3_k127_1116678_5 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 372.0
HFD3_k127_1116678_6 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 344.0
HFD3_k127_1116678_7 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002443 263.0
HFD3_k127_1116678_8 Bacterial sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000002455 239.0
HFD3_k127_1116678_9 TIGRFAM FemAB-related protein, PEP-CTERM - - - 0.00000000000000000000000000000000000000000000000000000000003154 235.0
HFD3_k127_1194455_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 6.049e-260 837.0
HFD3_k127_1194455_1 General secretory system II protein E domain protein K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000639 621.0
HFD3_k127_1194455_10 Imidazolone-5-propionate hydrolase K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003177 283.0
HFD3_k127_1194455_11 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009227 260.0
HFD3_k127_1194455_12 Secretin and TonB N terminus short domain K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000005141 242.0
HFD3_k127_1194455_13 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000006732 252.0
HFD3_k127_1194455_14 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000002472 209.0
HFD3_k127_1194455_15 - - - - 0.00000000000000000000000000001954 134.0
HFD3_k127_1194455_16 PFAM Phenylalanine and histidine ammonia-lyase K01745,K10775 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009072,GO:0009698,GO:0009699,GO:0009800,GO:0009803,GO:0009987,GO:0016043,GO:0016053,GO:0016829,GO:0016840,GO:0016841,GO:0019438,GO:0019748,GO:0019752,GO:0022607,GO:0032787,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044550,GO:0045548,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 4.3.1.24,4.3.1.3 0.000000000000000000000000007283 113.0
HFD3_k127_1194455_17 Tetratricopeptide repeat - - - 0.00000000000000000004446 106.0
HFD3_k127_1194455_18 PFAM Pilus assembly protein PilO K02664 - - 0.00000000000001112 82.0
HFD3_k127_1194455_19 Competence protein ComEA K02237 - - 0.00000000000002964 87.0
HFD3_k127_1194455_2 Two component, sigma54 specific, transcriptional regulator, Fis family K02667,K07713,K07714,K19641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005779 468.0
HFD3_k127_1194455_20 Outer membrane protein protective antigen OMA87 - - - 0.00000000000004813 86.0
HFD3_k127_1194455_21 Tetratricopeptide repeats - - - 0.0000000000002613 83.0
HFD3_k127_1194455_22 Prokaryotic N-terminal methylation motif K02456,K02650 - - 0.000000000001345 75.0
HFD3_k127_1194455_23 pilus assembly protein PilN K02663 - - 0.0000000004269 72.0
HFD3_k127_1194455_24 Pfam:N_methyl_2 K02650 - - 0.0000000004297 70.0
HFD3_k127_1194455_25 Tetratricopeptide repeat - - - 0.0000001863 64.0
HFD3_k127_1194455_27 Psort location CytoplasmicMembrane, score K16927 - - 0.0002909 51.0
HFD3_k127_1194455_3 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 436.0
HFD3_k127_1194455_4 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 429.0
HFD3_k127_1194455_5 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 441.0
HFD3_k127_1194455_6 PFAM Phenylalanine and histidine ammonia-lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 366.0
HFD3_k127_1194455_7 COG1715 Restriction endonuclease K07448 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 312.0
HFD3_k127_1194455_8 SMART helicase c2 K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 314.0
HFD3_k127_1194455_9 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009228 288.0
HFD3_k127_1310213_0 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 311.0
HFD3_k127_1310213_1 Protein of unknown function (DUF1697) - - - 0.000000000000000000000000000000000000000000001628 181.0
HFD3_k127_1310213_2 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000147 165.0
HFD3_k127_1310213_3 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000003396 152.0
HFD3_k127_1310213_4 - - - - 0.0000000000000000000000000001478 128.0
HFD3_k127_1310213_5 - - - - 0.0000002453 57.0
HFD3_k127_1310213_6 NmrA-like family - - - 0.000004038 52.0
HFD3_k127_1330303_0 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.0 1156.0
HFD3_k127_1330303_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000001209 224.0
HFD3_k127_1330303_2 PFAM Glycoside hydrolase 15-related - - - 0.00000000000000000148 101.0
HFD3_k127_1330303_3 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.0000000000000000247 94.0
HFD3_k127_1330303_4 Domain of unknown function (DUF4388) - - - 0.0000000004806 74.0
HFD3_k127_1330303_5 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000878 60.0
HFD3_k127_1360906_0 Argininosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 482.0
HFD3_k127_1360906_1 metallocarboxypeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 473.0
HFD3_k127_1360906_10 esterase - - - 0.0000000000000000000000000000000000978 155.0
HFD3_k127_1360906_11 Arginine repressor, DNA binding domain K03402 - - 0.000000000000000000000001817 109.0
HFD3_k127_1360906_12 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000003901 106.0
HFD3_k127_1360906_13 - - - - 0.00000000002845 74.0
HFD3_k127_1360906_14 metal cluster binding K03497 - - 0.000000005812 63.0
HFD3_k127_1360906_2 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 411.0
HFD3_k127_1360906_3 PFAM fumarate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006436 379.0
HFD3_k127_1360906_4 TIGRFAM acetylornithine and succinylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004661 319.0
HFD3_k127_1360906_5 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005304 297.0
HFD3_k127_1360906_6 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 GO:0000166,GO:0003674,GO:0005488,GO:0008150,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0097159,GO:1901265,GO:1901363 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000188 227.0
HFD3_k127_1360906_7 Transmembrane region of lysyl-tRNA synthetase K07027,K14205 - 2.3.2.3 0.00000000000000000000000000000000000000000000000000000000002521 228.0
HFD3_k127_1360906_8 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000009695 156.0
HFD3_k127_1380196_0 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005373 661.0
HFD3_k127_1380196_1 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 559.0
HFD3_k127_1380196_2 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003905 273.0
HFD3_k127_1380196_3 Peptidase family M50 K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000001621 244.0
HFD3_k127_1380196_4 Glycosyl transferase family 2 K12984 - - 0.00000000000000000000000000000002079 133.0
HFD3_k127_1380196_5 Surface antigen K07277 - - 0.00000000000000000000000000002594 136.0
HFD3_k127_1380196_6 Glycosyl transferases group 1 - - - 0.000000000000000000000000001017 127.0
HFD3_k127_1380196_7 protein conserved in bacteria K09800 - - 0.0000000000000004324 94.0
HFD3_k127_1380196_8 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000001472 59.0
HFD3_k127_1569246_0 Cytochrome C oxidase subunit II, periplasmic domain K00376 - 1.7.2.4 8.655e-230 729.0
HFD3_k127_1569246_1 electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 7.328e-202 645.0
HFD3_k127_1569246_10 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000007019 207.0
HFD3_k127_1569246_11 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000001843 194.0
HFD3_k127_1569246_12 ABC transporter K01990,K19340 - - 0.00000000000000000000000000000000000000000000000005624 193.0
HFD3_k127_1569246_13 ABC-2 family transporter protein K19341 - - 0.00000000000000000000000000000000000009293 158.0
HFD3_k127_1569246_14 lipoprotein involved in nitrous oxide reduction K19342 - - 0.0000000000000000000000000000000000003716 152.0
HFD3_k127_1569246_15 NnrS protein K07234 - - 0.000000000000000000000000000000002033 146.0
HFD3_k127_1569246_16 MoaE protein K03635 - 2.8.1.12 0.00000000000000000000000000000001295 134.0
HFD3_k127_1569246_17 cell septum assembly - - - 0.000000000000000000000000000006603 132.0
HFD3_k127_1569246_18 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.0000000000000000000000001201 120.0
HFD3_k127_1569246_19 cytochrome C - - - 0.0000000000000000000001336 109.0
HFD3_k127_1569246_2 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 395.0
HFD3_k127_1569246_20 CAAX protease self-immunity K07052 - - 0.00000000000000000000244 109.0
HFD3_k127_1569246_21 - - - - 0.00000000000355 79.0
HFD3_k127_1569246_22 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.0000000001593 74.0
HFD3_k127_1569246_23 ECF sigma factor K03088 - - 0.00000002049 64.0
HFD3_k127_1569246_24 Domain of unknown function (DUF4394) - - - 0.0000001237 65.0
HFD3_k127_1569246_25 lipoprotein involved in nitrous oxide reduction - - - 0.000006181 57.0
HFD3_k127_1569246_3 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 350.0
HFD3_k127_1569246_4 beta' subunit K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001268 288.0
HFD3_k127_1569246_5 PFAM bifunctional deaminase-reductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007093 294.0
HFD3_k127_1569246_6 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008016 264.0
HFD3_k127_1569246_7 Domain of unknown function (DUF1730) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000003396 271.0
HFD3_k127_1569246_8 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000006226 249.0
HFD3_k127_1569246_9 Periplasmic copper-binding protein (NosD) K07218 - - 0.000000000000000000000000000000000000000000000000000000000006142 229.0
HFD3_k127_1580090_0 PFAM aminotransferase, class I K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 532.0
HFD3_k127_1580090_1 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 515.0
HFD3_k127_1580090_10 Subtilase family K14645 GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000000000000000008081 220.0
HFD3_k127_1580090_11 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000002205 205.0
HFD3_k127_1580090_12 methyltransferase - - - 0.00000000000000000000000000000001613 145.0
HFD3_k127_1580090_13 Glycosyltransferase family 9 (heptosyltransferase) K02841,K02843 - - 0.000000000000000000000000000003987 134.0
HFD3_k127_1580090_14 - - - - 0.00000000000000000000000116 118.0
HFD3_k127_1580090_15 Tetratricopeptide repeat - - - 0.000001365 59.0
HFD3_k127_1580090_16 cellulose binding - - - 0.000001393 62.0
HFD3_k127_1580090_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 479.0
HFD3_k127_1580090_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 360.0
HFD3_k127_1580090_4 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 346.0
HFD3_k127_1580090_5 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 GO:0002097,GO:0002098,GO:0002143,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 340.0
HFD3_k127_1580090_6 PFAM Cys Met metabolism K01739,K01761 - 2.5.1.48,4.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 301.0
HFD3_k127_1580090_7 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000003019 256.0
HFD3_k127_1580090_8 GAF domain-containing protein K08968 - 1.8.4.14 0.00000000000000000000000000000000000000000000000000000001576 201.0
HFD3_k127_1580090_9 PFAM Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000005472 214.0
HFD3_k127_1642167_0 Type VI secretion protein, EvpB/VC_A0108, tail sheath K11900 - - 8.533e-216 679.0
HFD3_k127_1642167_1 C-terminal, D2-small domain, of ClpB protein K11907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006631 505.0
HFD3_k127_1642167_10 Type VI secretion system protein DotU K11892 - - 0.0000000000000000000000000004673 124.0
HFD3_k127_1642167_11 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000001568 130.0
HFD3_k127_1642167_12 Glycosyl transferases group 1 - - - 0.0000000000000000000000001154 126.0
HFD3_k127_1642167_13 Hep Hag repeat protein K01406,K21449 - 3.4.24.40 0.000000000000000000001898 105.0
HFD3_k127_1642167_14 CHAT domain - - - 0.000000000000000006239 98.0
HFD3_k127_1642167_15 protein conserved in bacteria K11905 - - 0.0000000000000004897 83.0
HFD3_k127_1642167_16 cellulose binding K00505 - 1.14.18.1 0.000000002959 70.0
HFD3_k127_1642167_17 protein conserved in bacteria K11906 - - 0.0001508 50.0
HFD3_k127_1642167_2 protein conserved in bacteria K11896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004509 499.0
HFD3_k127_1642167_3 ImcF-related N-terminal domain K11891 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 392.0
HFD3_k127_1642167_4 type VI secretion protein K11893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001031 277.0
HFD3_k127_1642167_5 Type VI secretion system effector, Hcp K11903 - - 0.0000000000000000000000000000000000000000000000000000000000000001502 224.0
HFD3_k127_1642167_6 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000003994 240.0
HFD3_k127_1642167_7 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ - - - 0.00000000000000000000000000000000000000000000000000000000000154 229.0
HFD3_k127_1642167_8 Type VI secretion system, VipA, VC_A0107 or Hcp2 K11901 - - 0.00000000000000000000000000000000000000000000000000318 186.0
HFD3_k127_1642167_9 Type VI secretion, TssG K11895 - - 0.000000000000000000000000000000000000000000008353 186.0
HFD3_k127_1765371_0 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 387.0
HFD3_k127_1765371_1 L-seryl-tRNA selenium transferase K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005695 383.0
HFD3_k127_1765371_10 PPIC-type PPIASE domain K03769,K03770 - 5.2.1.8 0.000000000000000000000000000000004218 146.0
HFD3_k127_1765371_11 Bifunctional nuclease K08999 - - 0.000000000000000000000000000001461 139.0
HFD3_k127_1765371_12 binds to the 23S rRNA K02939 - - 0.0000000000000000000000000001689 122.0
HFD3_k127_1765371_13 Cell Wall K01448 - 3.5.1.28 0.0000000000000000000007318 113.0
HFD3_k127_1765371_14 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000009324 97.0
HFD3_k127_1765371_15 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000001796 93.0
HFD3_k127_1765371_16 transport system, periplasmic component - - - 0.0000000003626 72.0
HFD3_k127_1765371_17 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000002713 64.0
HFD3_k127_1765371_18 Predicted membrane protein (DUF2232) K16785,K16786,K16787 - - 0.00001823 56.0
HFD3_k127_1765371_2 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000563 403.0
HFD3_k127_1765371_3 Branched-chain amino acid transport system / permease component K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 351.0
HFD3_k127_1765371_4 receptor K02014,K16089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 315.0
HFD3_k127_1765371_5 ABC transporter, ATP-binding protein K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008141 303.0
HFD3_k127_1765371_6 ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001156 297.0
HFD3_k127_1765371_7 ATP-binding region, ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001332 310.0
HFD3_k127_1765371_8 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000005953 161.0
HFD3_k127_1765371_9 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000001284 154.0
HFD3_k127_1802235_0 Transglycosylase K05366 GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.4.1.129,3.4.16.4 3.598e-196 635.0
HFD3_k127_1802235_1 Major Facilitator Superfamily K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 512.0
HFD3_k127_1802235_10 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 327.0
HFD3_k127_1802235_11 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 324.0
HFD3_k127_1802235_12 Transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008494 305.0
HFD3_k127_1802235_13 1,6-anhydro-N-acetyl-beta-muramic acid metabolic process K07106,K09001 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 2.7.1.170,4.2.1.126 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005309 287.0
HFD3_k127_1802235_14 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000003708 283.0
HFD3_k127_1802235_15 Belongs to the arginase family K01476,K01480 - 3.5.3.1,3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000001106 267.0
HFD3_k127_1802235_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003238 272.0
HFD3_k127_1802235_17 TIGRFAM molybdenum cofactor synthesis K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000007843 264.0
HFD3_k127_1802235_18 MazG nucleotide pyrophosphohydrolase domain K02499,K04765 - 3.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000008302 238.0
HFD3_k127_1802235_19 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000008945 244.0
HFD3_k127_1802235_2 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009477 484.0
HFD3_k127_1802235_20 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000009506 226.0
HFD3_k127_1802235_21 peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000001595 229.0
HFD3_k127_1802235_22 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000001322 209.0
HFD3_k127_1802235_23 PFAM Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000005756 206.0
HFD3_k127_1802235_24 Stage II sporulation protein K06381 - - 0.000000000000000000000000000000000000000000000006734 189.0
HFD3_k127_1802235_25 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000003387 184.0
HFD3_k127_1802235_26 - - - - 0.0000000000000000000000000000000000003098 145.0
HFD3_k127_1802235_27 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.0000000000000000000000000000007167 132.0
HFD3_k127_1802235_28 Protein of unknown function (DUF2442) - - - 0.0000000000000000000000002679 109.0
HFD3_k127_1802235_29 - - - - 0.00000000000000000000003022 115.0
HFD3_k127_1802235_3 Rieske (2fe-2S) K00499 - 1.14.15.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 477.0
HFD3_k127_1802235_30 Protein of unknown function (DUF433) - - - 0.00000000000000000000004112 102.0
HFD3_k127_1802235_31 oligosaccharyl transferase activity - - - 0.000000000000000000002625 111.0
HFD3_k127_1802235_32 Domain of unknown function (DUF1844) - - - 0.0000000000001089 76.0
HFD3_k127_1802235_34 - - - - 0.000000000235 69.0
HFD3_k127_1802235_35 nucleotide catabolic process K05996 - 3.4.17.18 0.00000000301 71.0
HFD3_k127_1802235_36 - - - - 0.0000000104 62.0
HFD3_k127_1802235_38 - - - - 0.0000001186 53.0
HFD3_k127_1802235_4 Metallo-peptidase family M12B Reprolysin-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 473.0
HFD3_k127_1802235_5 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 467.0
HFD3_k127_1802235_6 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 385.0
HFD3_k127_1802235_7 Pyrimidine nucleoside phosphorylase C-terminal domain K00756,K00758 - 2.4.2.2,2.4.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 387.0
HFD3_k127_1802235_8 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 340.0
HFD3_k127_1802235_9 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007965 348.0
HFD3_k127_1803080_0 MMPL family - - - 0.0 1088.0
HFD3_k127_1803080_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 477.0
HFD3_k127_1803080_10 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002714 306.0
HFD3_k127_1803080_11 Peptidase inhibitor I9 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000266 295.0
HFD3_k127_1803080_12 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003867 260.0
HFD3_k127_1803080_13 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002495 262.0
HFD3_k127_1803080_14 Phosphotransferase enzyme family K17880 - 2.7.1.119 0.00000000000000000000000000000000000000000000000000000000000000001216 237.0
HFD3_k127_1803080_15 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000006575 242.0
HFD3_k127_1803080_16 hydrolase activity, hydrolyzing N-glycosyl compounds - - - 0.0000000000000000000000000000000000000000000000000000000000003964 220.0
HFD3_k127_1803080_17 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000000000000000007772 211.0
HFD3_k127_1803080_18 WHG domain - - - 0.0000000000000000000000000000000000000000000000000000003078 200.0
HFD3_k127_1803080_19 membrane - - - 0.000000000000000000000000000000000000000000000000000008308 193.0
HFD3_k127_1803080_2 PFAM alpha beta hydrolase K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006307 464.0
HFD3_k127_1803080_20 PKD domain - - - 0.000000000000000000000000000000000000000001529 179.0
HFD3_k127_1803080_21 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000156 159.0
HFD3_k127_1803080_22 PFAM Abortive infection protein K07052 - - 0.0000000000000000000000000000000000000003297 158.0
HFD3_k127_1803080_23 - - - - 0.000000000000000000000000000000000000006555 157.0
HFD3_k127_1803080_24 Haem-binding domain - - - 0.00000000000000000000000000000000001745 139.0
HFD3_k127_1803080_25 - - - - 0.0000000000000000000000000000000004061 138.0
HFD3_k127_1803080_27 - - - - 0.00000000000000000000000000000005685 135.0
HFD3_k127_1803080_28 Protein of unknown function (DUF2975) - - - 0.0000000000000000000000000000001265 130.0
HFD3_k127_1803080_29 Transcriptional regulator K07727 - - 0.000000000000000000000000000004551 120.0
HFD3_k127_1803080_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008955 451.0
HFD3_k127_1803080_31 FlgD Ig-like domain - - - 0.00000000000000000000000006193 124.0
HFD3_k127_1803080_32 type I phosphodiesterase nucleotide pyrophosphatase - GO:0003674,GO:0003824,GO:0004035,GO:0004346,GO:0005488,GO:0005575,GO:0005623,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008877,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046872,GO:0046914,GO:0050308,GO:0050309,GO:0098519 - 0.0000000000000000000000001473 123.0
HFD3_k127_1803080_33 Cro/C1-type HTH DNA-binding domain - - - 0.000000000000000000000000327 111.0
HFD3_k127_1803080_34 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000001272 108.0
HFD3_k127_1803080_35 Domain of unknown function (DU1801) - - - 0.000000000000000000003625 99.0
HFD3_k127_1803080_36 Hep Hag repeat protein - - - 0.00000000000000000003103 106.0
HFD3_k127_1803080_37 amine dehydrogenase activity K21449 - - 0.00000000000000000004929 98.0
HFD3_k127_1803080_38 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella K01195 - 3.2.1.31 0.00000000000000000249 100.0
HFD3_k127_1803080_39 Protein of unknown function (DUF861) K06995 - - 0.000000000000000004445 91.0
HFD3_k127_1803080_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 411.0
HFD3_k127_1803080_41 Outer membrane protein beta-barrel domain - - - 0.00000000000002594 82.0
HFD3_k127_1803080_42 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000001496 75.0
HFD3_k127_1803080_43 hydrolase, family 9 K01179 - 3.2.1.4 0.0000000004965 73.0
HFD3_k127_1803080_45 Subtilase family - - - 0.00000001015 69.0
HFD3_k127_1803080_46 Evidence 5 No homology to any previously reported sequences - - - 0.00000002623 66.0
HFD3_k127_1803080_47 belongs to the sigma-70 factor family - - - 0.00000009118 64.0
HFD3_k127_1803080_48 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000002496 61.0
HFD3_k127_1803080_49 LVIVD repeat K01179 - 3.2.1.4 0.000004727 59.0
HFD3_k127_1803080_5 involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein K08282 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 411.0
HFD3_k127_1803080_50 CAAX protease self-immunity K07052 - - 0.000007692 57.0
HFD3_k127_1803080_51 polysaccharide catabolic process K01179 - 3.2.1.4 0.00001792 58.0
HFD3_k127_1803080_53 Integrase core domain K07497 - - 0.0004035 45.0
HFD3_k127_1803080_54 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0005536 46.0
HFD3_k127_1803080_6 bifunctional deaminase-reductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007971 358.0
HFD3_k127_1803080_7 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 372.0
HFD3_k127_1803080_8 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 313.0
HFD3_k127_1803080_9 PFAM PKD domain containing protein K11751 - 3.1.3.5,3.6.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 321.0
HFD3_k127_181230_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 3.015e-255 802.0
HFD3_k127_181230_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.306e-234 765.0
HFD3_k127_181230_10 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006549 320.0
HFD3_k127_181230_11 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 295.0
HFD3_k127_181230_12 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005386 294.0
HFD3_k127_181230_13 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001757 281.0
HFD3_k127_181230_14 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003054 291.0
HFD3_k127_181230_15 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006877 267.0
HFD3_k127_181230_16 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000003525 242.0
HFD3_k127_181230_17 TIGRFAM signal peptidase I K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000001249 226.0
HFD3_k127_181230_18 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000112 194.0
HFD3_k127_181230_19 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000006107 199.0
HFD3_k127_181230_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009704 649.0
HFD3_k127_181230_20 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000007995 192.0
HFD3_k127_181230_21 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000013 164.0
HFD3_k127_181230_22 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000001748 164.0
HFD3_k127_181230_23 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.000000000000000000000000000000000001378 162.0
HFD3_k127_181230_24 tRNA (adenine(22)-N(1))-methyltransferase K06967 - 2.1.1.217 0.000000000000000000000000000000001666 134.0
HFD3_k127_181230_25 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000002362 139.0
HFD3_k127_181230_26 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000214 125.0
HFD3_k127_181230_27 endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000002904 139.0
HFD3_k127_181230_28 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000009657 126.0
HFD3_k127_181230_29 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000002833 102.0
HFD3_k127_181230_3 Multicopper oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005801 538.0
HFD3_k127_181230_30 PFAM Tetratricopeptide repeat - - - 0.000000000000000000103 104.0
HFD3_k127_181230_31 GrpE K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000003277 102.0
HFD3_k127_181230_32 Zinc ribbon domain protein K07164 - - 0.0000000000000001955 89.0
HFD3_k127_181230_33 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000002702 79.0
HFD3_k127_181230_35 Patatin-like phospholipase K07001 - - 0.00000002933 66.0
HFD3_k127_181230_36 - - - - 0.00002636 55.0
HFD3_k127_181230_37 PFAM Patatin - - - 0.0001279 54.0
HFD3_k127_181230_4 TIGRFAM single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 454.0
HFD3_k127_181230_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000471 455.0
HFD3_k127_181230_6 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 417.0
HFD3_k127_181230_7 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0000988,GO:0000989,GO:0003674,GO:0003756,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010556,GO:0015035,GO:0015036,GO:0016020,GO:0016032,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0016989,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031326,GO:0032991,GO:0034641,GO:0034645,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0055114,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0140096,GO:0140110,GO:1901360,GO:1901576,GO:1903506,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 396.0
HFD3_k127_181230_8 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840 - 5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 382.0
HFD3_k127_181230_9 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 370.0
HFD3_k127_1857280_0 Cupin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005646 378.0
HFD3_k127_1857280_1 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 367.0
HFD3_k127_1857280_10 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000006816 80.0
HFD3_k127_1857280_11 lipolytic protein G-D-S-L family K20306 - - 0.000000003594 68.0
HFD3_k127_1857280_13 beta-galactosidase activity K01190 - 3.2.1.23 0.00004858 57.0
HFD3_k127_1857280_2 Transmembrane secretion effector K08225 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006697 365.0
HFD3_k127_1857280_3 amino acid activation for nonribosomal peptide biosynthetic process K05996 - 3.4.17.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007887 345.0
HFD3_k127_1857280_4 Protein of unknown function (DUF2891) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 331.0
HFD3_k127_1857280_5 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 299.0
HFD3_k127_1857280_6 Belongs to the UPF0502 family K09915 - - 0.00000000000000000000000000000000000000000000000000000000001037 218.0
HFD3_k127_1857280_7 glyoxalase III activity - - - 0.000000000000000000000000000000000000009792 156.0
HFD3_k127_1857280_8 peptidyl-tyrosine sulfation K13992 - - 0.00000000000000000000000000000000000001878 155.0
HFD3_k127_1857280_9 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000424 112.0
HFD3_k127_1890484_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 GO:0000018,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0071944,GO:0080090 - 2.658e-265 846.0
HFD3_k127_1890484_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 6.41e-255 818.0
HFD3_k127_1890484_10 membrane protein involved in D-alanine export - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003374 470.0
HFD3_k127_1890484_11 Belongs to the glycosyl hydrolase 57 family K22451 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005054 443.0
HFD3_k127_1890484_12 Tetratricopeptide repeat K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 434.0
HFD3_k127_1890484_13 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 408.0
HFD3_k127_1890484_14 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 396.0
HFD3_k127_1890484_15 PA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004627 404.0
HFD3_k127_1890484_16 beta Propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 378.0
HFD3_k127_1890484_17 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 392.0
HFD3_k127_1890484_18 PFAM aminotransferase class I and II K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 375.0
HFD3_k127_1890484_19 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 354.0
HFD3_k127_1890484_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 6.114e-212 678.0
HFD3_k127_1890484_20 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 356.0
HFD3_k127_1890484_21 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 333.0
HFD3_k127_1890484_22 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 328.0
HFD3_k127_1890484_23 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 314.0
HFD3_k127_1890484_24 PFAM ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 312.0
HFD3_k127_1890484_25 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009288 300.0
HFD3_k127_1890484_26 PFAM DAHP synthetase I KDSA K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009887 290.0
HFD3_k127_1890484_27 PFAM Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003336 282.0
HFD3_k127_1890484_28 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001047 273.0
HFD3_k127_1890484_29 succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000001258 278.0
HFD3_k127_1890484_3 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 602.0
HFD3_k127_1890484_30 Deoxynucleoside kinase K15518 - 2.7.1.113 0.000000000000000000000000000000000000000000000000000000000000000000007116 240.0
HFD3_k127_1890484_31 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000005214 256.0
HFD3_k127_1890484_32 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000002072 245.0
HFD3_k127_1890484_33 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000002234 225.0
HFD3_k127_1890484_34 Zinc-binding dehydrogenase K00001 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000002791 229.0
HFD3_k127_1890484_35 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000001582 211.0
HFD3_k127_1890484_36 Sugar isomerase (SIS) K15916 - 5.3.1.8,5.3.1.9 0.000000000000000000000000000000000000000000000000000000002654 228.0
HFD3_k127_1890484_37 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000001027 219.0
HFD3_k127_1890484_38 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000001194 196.0
HFD3_k127_1890484_39 PFAM ATP-binding region ATPase domain protein K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000002091 185.0
HFD3_k127_1890484_4 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006759 582.0
HFD3_k127_1890484_40 Cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000002106 179.0
HFD3_k127_1890484_41 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950,K13940 - 2.7.6.3,4.1.2.25 0.0000000000000000000000000000000000000000001279 164.0
HFD3_k127_1890484_42 Bis-adenosyl-polyphosphate hydrolase, FHIT domain-containing K19710 - 2.7.7.53 0.000000000000000000000000000000000000000003064 168.0
HFD3_k127_1890484_43 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000000000003209 165.0
HFD3_k127_1890484_44 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.000000000000000000000000000000000002103 150.0
HFD3_k127_1890484_45 ECF sigma factor - - - 0.000000000000000000000000000000000009511 143.0
HFD3_k127_1890484_46 SurA N-terminal domain K03770 - 5.2.1.8 0.00000000000000000000000000000000002662 155.0
HFD3_k127_1890484_47 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.00000000000000000000000000000003527 136.0
HFD3_k127_1890484_48 system, mannose fructose sorbose family IID component K02796 - - 0.00000000000000000000000000000422 137.0
HFD3_k127_1890484_49 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000006302 121.0
HFD3_k127_1890484_5 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 571.0
HFD3_k127_1890484_50 Belongs to the eIF-2B alpha beta delta subunits family K03680 - - 0.0000000000000000000000000001871 135.0
HFD3_k127_1890484_51 Domain of unknown function (DUF4034) - - - 0.000000000000000000000000001253 129.0
HFD3_k127_1890484_52 oligosaccharyl transferase activity - - - 0.000000000000000000000000005447 128.0
HFD3_k127_1890484_53 Belongs to the GcvT family K00605,K06980 - 2.1.2.10 0.00000000000000000000000003436 119.0
HFD3_k127_1890484_54 phosphoenolpyruvate-dependent sugar phosphotransferase system K02768,K02784,K03488,K05881,K08483,K11183,K11184,K11189,K11201 GO:0003674,GO:0003824,GO:0005215,GO:0005353,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005981,GO:0006109,GO:0006464,GO:0006476,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006950,GO:0006974,GO:0008047,GO:0008150,GO:0008152,GO:0008643,GO:0008645,GO:0008965,GO:0008982,GO:0009401,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010604,GO:0010675,GO:0010676,GO:0010906,GO:0010907,GO:0015144,GO:0015145,GO:0015149,GO:0015749,GO:0015755,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0018193,GO:0018205,GO:0019197,GO:0019213,GO:0019222,GO:0019538,GO:0019897,GO:0019898,GO:0022804,GO:0022857,GO:0022877,GO:0030234,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032445,GO:0032881,GO:0032991,GO:0033554,GO:0033558,GO:0034219,GO:0034983,GO:0035601,GO:0036211,GO:0043085,GO:0043170,GO:0043412,GO:0043467,GO:0043470,GO:0043471,GO:0043610,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045819,GO:0045913,GO:0047324,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051119,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0060255,GO:0062012,GO:0062013,GO:0065007,GO:0065009,GO:0070873,GO:0070875,GO:0071702,GO:0071704,GO:0071944,GO:0080090,GO:0090563,GO:0098732,GO:0098772,GO:0140096,GO:1901564 2.7.1.121,2.7.1.202,2.7.3.9 0.0000000000000000000000149 104.0
HFD3_k127_1890484_55 PTS system sorbose subfamily IIB component K19507 - - 0.0000000000000000000001418 108.0
HFD3_k127_1890484_57 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000002254 104.0
HFD3_k127_1890484_58 PFAM PKD domain containing protein K11751 - 3.1.3.5,3.6.1.45 0.00000000000000000004859 104.0
HFD3_k127_1890484_59 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.00000000000003396 79.0
HFD3_k127_1890484_6 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007017 582.0
HFD3_k127_1890484_60 PFAM Membrane protein of K08972 - - 0.00000000000004037 86.0
HFD3_k127_1890484_61 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000005083 83.0
HFD3_k127_1890484_62 succinate dehydrogenase K00241 - - 0.0000000000001054 82.0
HFD3_k127_1890484_63 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.0000000000002168 79.0
HFD3_k127_1890484_64 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000005028 68.0
HFD3_k127_1890484_65 LVIVD repeat K01179 - 3.2.1.4 0.000000000006227 76.0
HFD3_k127_1890484_66 Lipopolysaccharide-assembly, LptC-related - - - 0.000000000155 70.0
HFD3_k127_1890484_67 PFAM Cell envelope-related transcriptional attenuator domain - - - 0.00000001691 63.0
HFD3_k127_1890484_68 - - - - 0.0000001021 63.0
HFD3_k127_1890484_69 PTS system fructose IIA component K02793 - 2.7.1.191 0.0000003881 63.0
HFD3_k127_1890484_7 S-adenosylmethionine synthetase, C-terminal domain K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005458 529.0
HFD3_k127_1890484_70 Sigma 54 modulation protein K05808 - - 0.000002317 55.0
HFD3_k127_1890484_71 PTS system sorbose-specific iic component K02795,K19508 - - 0.000003034 60.0
HFD3_k127_1890484_72 Protein of unknown function (DUF664) - - - 0.000003269 57.0
HFD3_k127_1890484_73 - - - - 0.0001622 48.0
HFD3_k127_1890484_8 Ribonuclease E/G family K08301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009737 504.0
HFD3_k127_1890484_9 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01007,K08483 - 2.7.3.9,2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 492.0
HFD3_k127_1976697_0 Pyruvate kinase, barrel domain K00873 GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 550.0
HFD3_k127_1976697_1 Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 479.0
HFD3_k127_1976697_10 membrane - - - 0.00000000000000000000000000000000000000000000000000000000006834 227.0
HFD3_k127_1976697_11 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000005212 208.0
HFD3_k127_1976697_12 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.000000000000000000000000000000000000000000000000002156 188.0
HFD3_k127_1976697_13 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000001768 190.0
HFD3_k127_1976697_14 - - - - 0.0000000000000000000000000000000000000000000022 175.0
HFD3_k127_1976697_15 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000008549 171.0
HFD3_k127_1976697_16 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000005826 175.0
HFD3_k127_1976697_17 Transcriptional regulator, TraR DksA family K06204 - - 0.00000000000000000000000000000000001905 147.0
HFD3_k127_1976697_18 Peptidase family C25 - - - 0.0000000000000000000000006757 123.0
HFD3_k127_1976697_19 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.00000000000000000000003668 108.0
HFD3_k127_1976697_2 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 438.0
HFD3_k127_1976697_20 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000004708 112.0
HFD3_k127_1976697_21 YGGT family K02221 - - 0.00000000000000000000006194 101.0
HFD3_k127_1976697_22 oligosaccharyl transferase activity - - - 0.000000000000000001226 101.0
HFD3_k127_1976697_23 Ami_3 K01448 - 3.5.1.28 0.000000000000000009854 98.0
HFD3_k127_1976697_24 Anti-sigma regulatory factor (Ser Thr protein kinase) K04757,K06379,K08282 - 2.7.11.1 0.0000000000000004189 86.0
HFD3_k127_1976697_25 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000005265 86.0
HFD3_k127_1976697_26 Putative glutamine amidotransferase - - - 0.00000000000007904 79.0
HFD3_k127_1976697_27 oligosaccharyl transferase activity - - - 0.0000000000006663 82.0
HFD3_k127_1976697_28 Sporulation and spore germination - - - 0.0000000000397 76.0
HFD3_k127_1976697_29 Spore coat protein CotH - - - 0.0000000005313 69.0
HFD3_k127_1976697_3 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007475 413.0
HFD3_k127_1976697_31 SurA N-terminal domain K03771 - 5.2.1.8 0.0000003611 64.0
HFD3_k127_1976697_32 Belongs to the UPF0235 family K09131 - - 0.000001025 63.0
HFD3_k127_1976697_33 - - - - 0.00009764 46.0
HFD3_k127_1976697_35 Endonuclease/Exonuclease/phosphatase family K07004 - - 0.0003789 53.0
HFD3_k127_1976697_4 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 319.0
HFD3_k127_1976697_5 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006052 310.0
HFD3_k127_1976697_6 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 303.0
HFD3_k127_1976697_7 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001385 284.0
HFD3_k127_1976697_8 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000007195 277.0
HFD3_k127_1976697_9 tRNA processing K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003144 257.0
HFD3_k127_2036085_0 Intein splicing domain K02469 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 0.0 1234.0
HFD3_k127_2036085_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.707e-252 788.0
HFD3_k127_2036085_10 Domain of unknown function (DUF5118) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 548.0
HFD3_k127_2036085_101 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.0005292 53.0
HFD3_k127_2036085_11 Nucleoside recognition - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 509.0
HFD3_k127_2036085_12 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 509.0
HFD3_k127_2036085_13 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 411.0
HFD3_k127_2036085_14 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 406.0
HFD3_k127_2036085_15 Peptidase dimerisation domain K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 386.0
HFD3_k127_2036085_16 Phosphate transport system permease K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005161 384.0
HFD3_k127_2036085_17 peptide catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 387.0
HFD3_k127_2036085_18 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 353.0
HFD3_k127_2036085_19 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 347.0
HFD3_k127_2036085_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 4.233e-248 781.0
HFD3_k127_2036085_20 Peptidase M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000852 373.0
HFD3_k127_2036085_21 PBP superfamily domain K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 342.0
HFD3_k127_2036085_22 Sterol carrier protein domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004538 347.0
HFD3_k127_2036085_23 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005503 352.0
HFD3_k127_2036085_24 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 350.0
HFD3_k127_2036085_25 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 321.0
HFD3_k127_2036085_26 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 319.0
HFD3_k127_2036085_27 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000054 327.0
HFD3_k127_2036085_28 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 309.0
HFD3_k127_2036085_29 Methionine aminopeptidase K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 293.0
HFD3_k127_2036085_3 cysteine protease - - - 1.696e-231 737.0
HFD3_k127_2036085_30 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000793 286.0
HFD3_k127_2036085_31 Uncharacterized protein conserved in bacteria (DUF2330) K00347,K21163 GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008144,GO:0008150,GO:0008152,GO:0010181,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0019842,GO:0030001,GO:0030964,GO:0032553,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0044464,GO:0048037,GO:0050136,GO:0050662,GO:0051179,GO:0051234,GO:0055114,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:1901265,GO:1901363,GO:1902444,GO:1902494 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003339 279.0
HFD3_k127_2036085_32 Domain of unknown function (DUF4162) K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005651 279.0
HFD3_k127_2036085_33 ATP:ADP antiporter activity K01932,K03301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003828 289.0
HFD3_k127_2036085_34 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003918 270.0
HFD3_k127_2036085_35 response regulator K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003909 259.0
HFD3_k127_2036085_36 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000003953 254.0
HFD3_k127_2036085_37 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000005072 246.0
HFD3_k127_2036085_38 Signal transduction histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000006464 251.0
HFD3_k127_2036085_39 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000002235 233.0
HFD3_k127_2036085_4 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 8.472e-197 631.0
HFD3_k127_2036085_40 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000002066 228.0
HFD3_k127_2036085_41 YCII-related domain - - - 0.00000000000000000000000000000000000000000000000000000000001935 211.0
HFD3_k127_2036085_42 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000003788 234.0
HFD3_k127_2036085_43 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000007326 208.0
HFD3_k127_2036085_44 PFAM response regulator receiver K02483,K07658,K07668 - - 0.0000000000000000000000000000000000000000000000000000000321 212.0
HFD3_k127_2036085_45 metallophosphoesterase K07096 - - 0.000000000000000000000000000000000000000000000000000002653 201.0
HFD3_k127_2036085_46 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000983 199.0
HFD3_k127_2036085_47 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000185 198.0
HFD3_k127_2036085_48 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000001591 203.0
HFD3_k127_2036085_49 Biotin-lipoyl like K01993 - - 0.0000000000000000000000000000000000000000000000001309 202.0
HFD3_k127_2036085_5 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 631.0
HFD3_k127_2036085_50 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000002529 192.0
HFD3_k127_2036085_51 pyrroloquinoline quinone binding K01176 - 3.2.1.1 0.0000000000000000000000000000000000000000000000004281 201.0
HFD3_k127_2036085_52 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000007316 176.0
HFD3_k127_2036085_53 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000002393 197.0
HFD3_k127_2036085_54 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000000003748 193.0
HFD3_k127_2036085_55 Domain of unknown function (DUF1929) - - - 0.0000000000000000000000000000000000000000000005722 192.0
HFD3_k127_2036085_56 phosphate-selective porin O and P - - - 0.000000000000000000000000000000000000000000006537 181.0
HFD3_k127_2036085_57 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000001431 166.0
HFD3_k127_2036085_58 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000001149 174.0
HFD3_k127_2036085_59 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63 0.00000000000000000000000000000000000000009874 164.0
HFD3_k127_2036085_6 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 610.0
HFD3_k127_2036085_61 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.000000000000000000000000000000000000006391 149.0
HFD3_k127_2036085_62 2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase K01625 - 4.1.2.14,4.1.3.42 0.0000000000000000000000000000000000002321 153.0
HFD3_k127_2036085_63 B3/4 domain - - - 0.0000000000000000000000000000000000004126 149.0
HFD3_k127_2036085_64 Glycogen debranching enzyme - - - 0.00000000000000000000000000000000001851 155.0
HFD3_k127_2036085_65 SprB repeat - - - 0.000000000000000000000000000000008071 149.0
HFD3_k127_2036085_66 EXOIII K02342 - 2.7.7.7 0.0000000000000000000000000000002828 136.0
HFD3_k127_2036085_67 Redoxin K03386 - 1.11.1.15 0.000000000000000000000000000001272 128.0
HFD3_k127_2036085_68 - - - - 0.000000000000000000000000000001551 138.0
HFD3_k127_2036085_69 Photosynthesis system II assembly factor YCF48 - - - 0.000000000000000000000000000003167 138.0
HFD3_k127_2036085_7 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 563.0
HFD3_k127_2036085_70 COG2143 Thioredoxin-related protein - - - 0.000000000000000000000000000006807 126.0
HFD3_k127_2036085_71 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella K01195 - 3.2.1.31 0.00000000000000000000000000003932 136.0
HFD3_k127_2036085_72 of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000001321 121.0
HFD3_k127_2036085_73 Domain of unknown function (DUF1929) - - - 0.00000000000000000000000005396 124.0
HFD3_k127_2036085_74 Domain of unknown function (DUF4081) K06976 - - 0.000000000000000000000002727 113.0
HFD3_k127_2036085_75 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides - - - 0.0000000000000000000003067 110.0
HFD3_k127_2036085_76 FlgD Ig-like domain - - - 0.000000000000000000004563 109.0
HFD3_k127_2036085_77 - - - - 0.0000000000000000163 98.0
HFD3_k127_2036085_78 BlaR1 peptidase M56 - - - 0.00000000000000002963 93.0
HFD3_k127_2036085_79 PspC domain K03973 - - 0.00000000000000004241 83.0
HFD3_k127_2036085_8 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 530.0
HFD3_k127_2036085_80 PFAM Class I peptide chain release factor K15034 - - 0.00000000000000006364 84.0
HFD3_k127_2036085_81 Predicted membrane protein (DUF2079) - - - 0.0000000000000002871 93.0
HFD3_k127_2036085_82 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000007827 93.0
HFD3_k127_2036085_83 PFAM Isoprenylcysteine carboxyl methyltransferase K00587 - 2.1.1.100 0.000000000000002461 86.0
HFD3_k127_2036085_84 - - - - 0.000000000000005406 80.0
HFD3_k127_2036085_85 extracellular matrix structural constituent - - - 0.00000000000005039 85.0
HFD3_k127_2036085_86 Acetyltransferase (GNAT) family K00657 - 2.3.1.57 0.0000000000005886 72.0
HFD3_k127_2036085_87 Periplasmic or secreted lipoprotein - - - 0.000000000001574 79.0
HFD3_k127_2036085_88 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000254 77.0
HFD3_k127_2036085_89 aspartic-type endopeptidase activity K06985,K07272,K20543,K21007 - - 0.000000004488 69.0
HFD3_k127_2036085_9 Uncharacterized protein conserved in bacteria (DUF2330) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 515.0
HFD3_k127_2036085_90 alginic acid biosynthetic process K01729,K12287 - 4.2.2.3 0.00000002803 68.0
HFD3_k127_2036085_91 Protein of unknown function (DUF721) - - - 0.0000001577 64.0
HFD3_k127_2036085_92 YacP-like NYN domain K06962 - - 0.0000003634 59.0
HFD3_k127_2036085_93 Bacterial Ig-like domain (group 1) - - - 0.0000009025 62.0
HFD3_k127_2036085_94 Glyoxal oxidase N-terminus K20929 - 1.2.3.15 0.000009726 60.0
HFD3_k127_2036085_95 AsmA family K07289 - - 0.00001186 59.0
HFD3_k127_2036085_96 cellulose binding - - - 0.00001272 57.0
HFD3_k127_2036085_97 Endonuclease I - - - 0.00002819 57.0
HFD3_k127_2036085_98 nitrile biosynthetic process - - - 0.00002923 58.0
HFD3_k127_2036085_99 domain, Protein K01179,K13735,K21449 - 3.2.1.4 0.0001206 55.0
HFD3_k127_2036312_0 ATP ADP translocase K03301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006993 396.0
HFD3_k127_2036312_1 Pyridine nucleotide-disulphide oxidoreductase K00529,K18227,K18249 - 1.18.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006028 346.0
HFD3_k127_2036312_10 COG3307 Lipid A core - O-antigen ligase and related enzymes K18814 - - 0.0005444 54.0
HFD3_k127_2036312_2 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 330.0
HFD3_k127_2036312_4 MATE efflux family protein - - - 0.000000000000000000000000000000000000000000000000000000000000007267 246.0
HFD3_k127_2036312_5 Domain of unknown function (DUF1929) - - - 0.00000000000000000000000217 119.0
HFD3_k127_2036312_6 - - - - 0.000000000000002111 84.0
HFD3_k127_2036312_7 extracellular matrix structural constituent - - - 0.000000000000007164 88.0
HFD3_k127_2036312_8 Calcineurin-like phosphoesterase K14379 - 3.1.3.2 0.00000000632 70.0
HFD3_k127_2036312_9 Flagellar hook capping protein - N-terminal region K02389 - - 0.0004028 53.0
HFD3_k127_2061225_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000414 473.0
HFD3_k127_2061225_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K09698 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:2001065 6.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008806 450.0
HFD3_k127_2061225_2 siderophore transport K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005573 460.0
HFD3_k127_2061225_3 M42 glutamyl aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009425 414.0
HFD3_k127_2061225_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 322.0
HFD3_k127_2061225_5 Transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000002144 248.0
HFD3_k127_2061225_6 Mechanosensitive ion channel K22044 - - 0.00000000000000000000000000000000000000000000000159 190.0
HFD3_k127_2061225_7 Belongs to the peptidase S26 family - - - 0.0000000000000000000000000000000000000009401 154.0
HFD3_k127_2061225_8 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000005526 127.0
HFD3_k127_2061225_9 - - - - 0.0000001184 60.0
HFD3_k127_21589_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1234.0
HFD3_k127_21589_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 3.178e-286 891.0
HFD3_k127_21589_10 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000004453 218.0
HFD3_k127_21589_11 response regulator receiver - - - 0.00000000000000000000000000000000000001744 167.0
HFD3_k127_21589_12 PFAM blue (type 1) copper domain protein - - - 0.00000000000000001391 96.0
HFD3_k127_21589_13 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000005111 81.0
HFD3_k127_21589_2 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008653 488.0
HFD3_k127_21589_3 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K04127,K11325,K21174 - 5.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 489.0
HFD3_k127_21589_4 succinyl-diaminopimelate desuccinylase activity K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 459.0
HFD3_k127_21589_5 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 409.0
HFD3_k127_21589_6 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 349.0
HFD3_k127_21589_7 drug transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 342.0
HFD3_k127_21589_8 PFAM RNA binding S1 domain protein K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003864 294.0
HFD3_k127_21589_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007818 287.0
HFD3_k127_2162152_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 8.874e-209 659.0
HFD3_k127_2162152_1 POT family K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 526.0
HFD3_k127_2162152_2 PFAM ABC-1 domain protein K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 479.0
HFD3_k127_2162152_3 Sigma-54 interaction domain K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 413.0
HFD3_k127_2162152_4 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000002175 179.0
HFD3_k127_2162152_5 Polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000001636 133.0
HFD3_k127_2162152_6 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000000001878 118.0
HFD3_k127_2162152_7 Phosphate acyltransferases K13507 - 2.3.1.15,2.3.1.42 0.000000000000000625 93.0
HFD3_k127_2162152_8 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07658 - - 0.00006322 51.0
HFD3_k127_2226397_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007926 505.0
HFD3_k127_2226397_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004888 394.0
HFD3_k127_2226397_10 polysaccharide catabolic process K01179,K01218 - 3.2.1.4,3.2.1.78 0.000001091 63.0
HFD3_k127_2226397_11 His Kinase A (phosphoacceptor) domain - - - 0.000001235 51.0
HFD3_k127_2226397_12 Endonuclease Exonuclease Phosphatase - - - 0.000003279 61.0
HFD3_k127_2226397_2 Predicted membrane protein (DUF2157) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 334.0
HFD3_k127_2226397_3 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004096 287.0
HFD3_k127_2226397_4 SecD/SecF GG Motif K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000002413 234.0
HFD3_k127_2226397_5 Domain of unknown function (DUF4159) - - - 0.00000000000000000000000000000000000000000000000000000000000000003948 233.0
HFD3_k127_2226397_6 Domain of unknown function (DUF4401) - - - 0.000000000000000000000000000000000000000000000000000000000000003933 241.0
HFD3_k127_2226397_7 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000834 246.0
HFD3_k127_2226397_8 GDYXXLXY protein - - - 0.00000000000000000000000000000000000000000000000000007554 190.0
HFD3_k127_2226397_9 protein secretion K08651 - 3.4.21.66 0.000000000000000000000000000000000000000000000001761 201.0
HFD3_k127_228115_0 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 297.0
HFD3_k127_228115_1 ABC-2 family transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000002865 235.0
HFD3_k127_228115_2 PSP1 C-terminal conserved region - - - 0.00000000000000000000000000000000000000000000000000000000000000004859 236.0
HFD3_k127_228115_3 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000001478 189.0
HFD3_k127_228115_4 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000001305 177.0
HFD3_k127_228115_5 Peptidase family M23 K21471 GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - 0.0000000000000000000000000000000000000000000666 177.0
HFD3_k127_228115_6 AntiSigma factor - - - 0.0000000000000000000000000000276 130.0
HFD3_k127_228115_9 - - - - 0.000000000144 72.0
HFD3_k127_2335061_0 Pyridoxal-dependent decarboxylase conserved domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 534.0
HFD3_k127_2335061_1 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 338.0
HFD3_k127_2335061_10 - - - - 0.0000000000000000004721 87.0
HFD3_k127_2335061_11 Helix-turn-helix diphteria tox regulatory element K03709 - - 0.000000000000000005547 91.0
HFD3_k127_2335061_12 DinB family - - - 0.000000005659 65.0
HFD3_k127_2335061_13 Domain of unknown function DUF11 - - - 0.0000004185 61.0
HFD3_k127_2335061_2 - K12065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 327.0
HFD3_k127_2335061_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007564 264.0
HFD3_k127_2335061_4 Cupin superfamily (DUF985) K09705 - - 0.00000000000000000000000000000000000000000000674 188.0
HFD3_k127_2335061_5 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000003368 161.0
HFD3_k127_2335061_6 lyase activity - - - 0.000000000000000000000000003577 128.0
HFD3_k127_2335061_7 - - - - 0.0000000000000000000000004045 118.0
HFD3_k127_2335061_8 TonB-dependent Receptor Plug Domain K16092 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0006810,GO:0006811,GO:0008150,GO:0015075,GO:0015267,GO:0015318,GO:0015889,GO:0015893,GO:0016020,GO:0016021,GO:0019904,GO:0022803,GO:0022838,GO:0022857,GO:0031224,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0050896,GO:0051179,GO:0051180,GO:0051181,GO:0051234,GO:0055085,GO:0071702,GO:0071705 - 0.00000000000000000002304 107.0
HFD3_k127_2335061_9 FMN_bind - - - 0.00000000000000000008735 105.0
HFD3_k127_2350643_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 551.0
HFD3_k127_2350643_1 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 461.0
HFD3_k127_2350643_2 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003941 377.0
HFD3_k127_2350643_3 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000000000000003493 174.0
HFD3_k127_2350643_4 VanZ like family - - - 0.00000001536 63.0
HFD3_k127_2350643_6 Pkd domain containing protein - - - 0.0000001476 64.0
HFD3_k127_2350643_7 peroxiredoxin activity K00384,K03564,K12057,K12267,K21636 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.1.98.6,1.11.1.15,1.8.1.9,1.8.4.11,1.8.4.12 0.0001495 54.0
HFD3_k127_2359994_0 H( )-stimulated, divalent metal cation uptake system K03322 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 593.0
HFD3_k127_2359994_1 Prolyl oligopeptidase K01322 - 3.4.21.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 579.0
HFD3_k127_2359994_10 - K07018 - - 0.000000000000000000000000000000000000000001754 170.0
HFD3_k127_2359994_11 Trypsin-like serine protease K01337 - 3.4.21.50 0.0000000000000000000000000000001013 136.0
HFD3_k127_2359994_12 Type IV pilus assembly protein PilM; K02662 - - 0.00000000000000000000000000008468 129.0
HFD3_k127_2359994_13 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000003606 102.0
HFD3_k127_2359994_14 PA14 domain - - - 0.000000000000003639 89.0
HFD3_k127_2359994_15 - - - - 0.000000000006428 78.0
HFD3_k127_2359994_16 PFAM Uncharacterised protein family (UPF0164) - - - 0.000000001533 72.0
HFD3_k127_2359994_17 cell adhesion K02650,K02682 - - 0.000000003054 70.0
HFD3_k127_2359994_18 Belongs to the peptidase S8 family K13276 - - 0.000005827 59.0
HFD3_k127_2359994_19 Putative MetA-pathway of phenol degradation - - - 0.00004755 54.0
HFD3_k127_2359994_2 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02504,K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 503.0
HFD3_k127_2359994_3 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 436.0
HFD3_k127_2359994_4 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005484 370.0
HFD3_k127_2359994_5 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 344.0
HFD3_k127_2359994_6 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008137 308.0
HFD3_k127_2359994_7 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001013 274.0
HFD3_k127_2359994_8 type II and III secretion system protein K02507,K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000003484 241.0
HFD3_k127_2359994_9 iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000000000002219 191.0
HFD3_k127_2380502_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1280.0
HFD3_k127_2380502_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.351e-253 802.0
HFD3_k127_2380502_2 Amino acid permease - - - 3.991e-202 650.0
HFD3_k127_2380502_3 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 581.0
HFD3_k127_2380502_4 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 483.0
HFD3_k127_2380502_5 Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 378.0
HFD3_k127_2380502_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000004112 136.0
HFD3_k127_2380502_7 Universal stress protein family - - - 0.0000000000001052 78.0
HFD3_k127_2380502_8 - - - - 0.000000000006591 76.0
HFD3_k127_2404462_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005868 502.0
HFD3_k127_2404462_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 409.0
HFD3_k127_2404462_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006418 295.0
HFD3_k127_2404462_3 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000527 288.0
HFD3_k127_2404462_4 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00015,K00058,K16843 - 1.1.1.26,1.1.1.310,1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000194 215.0
HFD3_k127_2404462_5 riboflavin synthase, alpha K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000607 207.0
HFD3_k127_2404462_6 stage II sporulation K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000001269 214.0
HFD3_k127_2404462_7 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464 2.5.1.78 0.000000000000000000000000000009751 136.0
HFD3_k127_2404462_8 Putative zinc-finger - - - 0.00000001525 60.0
HFD3_k127_2443132_0 Peptidase dimerisation domain - - - 1.678e-246 772.0
HFD3_k127_2443132_1 Beta-lactamase - - - 4.604e-212 681.0
HFD3_k127_2443132_10 Type II secretory pathway, component ExeA K12283 - - 0.00000000000000000000000000006864 136.0
HFD3_k127_2443132_11 domain, Protein - - - 0.00000000000000000000000003988 126.0
HFD3_k127_2443132_12 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0000000000001922 85.0
HFD3_k127_2443132_13 Domain of unknown function (DUF4394) - - - 0.000000007101 67.0
HFD3_k127_2443132_14 cellulase activity K01179,K01361,K13277,K21449 - 3.2.1.4,3.4.21.96 0.00000003604 67.0
HFD3_k127_2443132_16 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.000004629 49.0
HFD3_k127_2443132_17 Cadherin domain - - - 0.00006178 57.0
HFD3_k127_2443132_18 long-chain fatty acid transporting porin activity - - - 0.0007594 51.0
HFD3_k127_2443132_2 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K15738 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010528,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031323,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0070894,GO:0071944,GO:0080090,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 619.0
HFD3_k127_2443132_3 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 455.0
HFD3_k127_2443132_4 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 386.0
HFD3_k127_2443132_5 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003741 303.0
HFD3_k127_2443132_6 Asparaginase, N-terminal K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000005551 235.0
HFD3_k127_2443132_7 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000002574 209.0
HFD3_k127_2443132_8 - - - - 0.00000000000000000000000000000000000000000000000000001663 196.0
HFD3_k127_2443132_9 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000004945 138.0
HFD3_k127_2470399_0 Hep Hag repeat protein - - - 1.853e-247 804.0
HFD3_k127_2470399_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000561 610.0
HFD3_k127_2470399_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 399.0
HFD3_k127_2470399_11 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009895 423.0
HFD3_k127_2470399_12 Cupin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 376.0
HFD3_k127_2470399_13 PFAM sigma-54 factor interaction domain-containing protein K10941 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006706 381.0
HFD3_k127_2470399_14 Integral membrane protein TerC family K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002529 372.0
HFD3_k127_2470399_15 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 364.0
HFD3_k127_2470399_16 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005806 362.0
HFD3_k127_2470399_17 synthase K16167 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005685 361.0
HFD3_k127_2470399_18 CAAX protease self-immunity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008217 322.0
HFD3_k127_2470399_19 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 334.0
HFD3_k127_2470399_2 Histidine kinase K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 535.0
HFD3_k127_2470399_20 CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006329 322.0
HFD3_k127_2470399_21 Beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 338.0
HFD3_k127_2470399_22 Competence-damaged protein K03742 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 308.0
HFD3_k127_2470399_23 ABC transporter K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 296.0
HFD3_k127_2470399_24 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004082 299.0
HFD3_k127_2470399_25 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006668 295.0
HFD3_k127_2470399_26 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002258 293.0
HFD3_k127_2470399_27 Pregnancy-associated plasma protein-A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009183 254.0
HFD3_k127_2470399_28 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000009467 239.0
HFD3_k127_2470399_29 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000003653 254.0
HFD3_k127_2470399_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 514.0
HFD3_k127_2470399_30 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000004118 250.0
HFD3_k127_2470399_31 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000228 240.0
HFD3_k127_2470399_32 PFAM ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000000000000000000008411 229.0
HFD3_k127_2470399_33 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000002602 230.0
HFD3_k127_2470399_34 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000002735 228.0
HFD3_k127_2470399_35 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000003485 215.0
HFD3_k127_2470399_36 Domain of unknown function (DUF4386) - - - 0.0000000000000000000000000000000000000000000000000001567 194.0
HFD3_k127_2470399_37 Aldo Keto reductase - - - 0.00000000000000000000000000000000000000000000000005699 199.0
HFD3_k127_2470399_38 cell septum assembly - - - 0.0000000000000000000000000000000000000000000000002336 191.0
HFD3_k127_2470399_39 - - - - 0.0000000000000000000000000000000000000000000246 176.0
HFD3_k127_2470399_4 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 532.0
HFD3_k127_2470399_40 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000002385 177.0
HFD3_k127_2470399_41 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000604 163.0
HFD3_k127_2470399_42 Isoprenylcysteine carboxyl methyltransferase K16168 - - 0.000000000000000000000000000000000000005047 159.0
HFD3_k127_2470399_43 OsmC-like protein K04063 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006970,GO:0006972,GO:0006979,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748 - 0.00000000000000000000000000000000000009204 154.0
HFD3_k127_2470399_44 ECF sigma factor - - - 0.000000000000000000000000000000000001345 149.0
HFD3_k127_2470399_45 SURF4 family K15977 - - 0.000000000000000000000000000000000154 148.0
HFD3_k127_2470399_46 - - - - 0.000000000000000000000000000000003154 138.0
HFD3_k127_2470399_47 - - - - 0.000000000000000000000000000000003728 139.0
HFD3_k127_2470399_48 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000001732 145.0
HFD3_k127_2470399_5 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 480.0
HFD3_k127_2470399_50 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.0000000000000000000000000000485 127.0
HFD3_k127_2470399_51 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000007465 126.0
HFD3_k127_2470399_52 Thioredoxin-like - - - 0.00000000000000000000000000009777 130.0
HFD3_k127_2470399_53 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella K01195 - 3.2.1.31 0.00000000000000000000000001771 128.0
HFD3_k127_2470399_54 - - - - 0.00000000000000000000000002524 115.0
HFD3_k127_2470399_55 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.00000000000000000000000005499 117.0
HFD3_k127_2470399_56 glycosyl transferase, family 39 - - - 0.0000000000000000000000007471 120.0
HFD3_k127_2470399_57 domain, Protein - - - 0.000000000000000000000005165 116.0
HFD3_k127_2470399_58 - - - - 0.00000000000000000000001555 116.0
HFD3_k127_2470399_59 Protein of unknown function (DUF3455) - - - 0.0000000000000000000002409 109.0
HFD3_k127_2470399_6 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 498.0
HFD3_k127_2470399_60 Trypsin-like serine protease K01318 GO:0005575,GO:0005576 3.4.21.19 0.000000000000000000002032 106.0
HFD3_k127_2470399_61 Could be involved in septation K06412 - - 0.0000000000000000000386 104.0
HFD3_k127_2470399_62 PFAM phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.0000000000000000001527 101.0
HFD3_k127_2470399_63 PFAM Roadblock LC7 family protein - - - 0.000000000000000005571 93.0
HFD3_k127_2470399_64 COG1621 Beta-fructosidases (levanase invertase) - - - 0.00000000000000008672 95.0
HFD3_k127_2470399_65 PFAM blue (type 1) copper domain protein - - - 0.0000000000000001181 95.0
HFD3_k127_2470399_66 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000001715 94.0
HFD3_k127_2470399_67 heme-binding sites - - - 0.0000000000000003308 89.0
HFD3_k127_2470399_68 Modulates RecA activity K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000008611 90.0
HFD3_k127_2470399_69 - - - - 0.000000000000002581 81.0
HFD3_k127_2470399_7 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 474.0
HFD3_k127_2470399_70 cheY-homologous receiver domain - - - 0.000000000000009076 89.0
HFD3_k127_2470399_71 alginic acid biosynthetic process K01729,K17713 - 4.2.2.3 0.00000000001273 76.0
HFD3_k127_2470399_72 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K01115 - 3.1.4.4 0.00000000002502 77.0
HFD3_k127_2470399_73 extracellular matrix structural constituent - - - 0.0000000004041 74.0
HFD3_k127_2470399_74 Prolyl oligopeptidase family - - - 0.000001239 59.0
HFD3_k127_2470399_75 cellulose binding K00505 - 1.14.18.1 0.000006604 60.0
HFD3_k127_2470399_77 Fungalysin/Thermolysin Propeptide Motif - - - 0.0001808 55.0
HFD3_k127_2470399_78 SprB repeat - - - 0.0003978 48.0
HFD3_k127_2470399_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 453.0
HFD3_k127_2470399_9 phosphorelay signal transduction system K02437 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005138 443.0
HFD3_k127_2624617_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1245.0
HFD3_k127_2624617_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.067e-206 663.0
HFD3_k127_2624617_10 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 360.0
HFD3_k127_2624617_11 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 342.0
HFD3_k127_2624617_12 RecF/RecN/SMC N terminal domain K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 336.0
HFD3_k127_2624617_13 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 309.0
HFD3_k127_2624617_14 Hexapeptide repeat of succinyl-transferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005422 304.0
HFD3_k127_2624617_15 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000338 258.0
HFD3_k127_2624617_16 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000001053 255.0
HFD3_k127_2624617_17 Belongs to the FPP GGPP synthase family K13789 GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0071704,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000001387 215.0
HFD3_k127_2624617_18 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07710 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000001593 208.0
HFD3_k127_2624617_19 Phage integrase, N-terminal SAM-like domain K03733 - - 0.000000000000000000000000000000000000000000000000001944 185.0
HFD3_k127_2624617_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 523.0
HFD3_k127_2624617_20 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.000000000000000000000000000000000000000000000000002849 207.0
HFD3_k127_2624617_21 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000003905 183.0
HFD3_k127_2624617_22 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000006008 158.0
HFD3_k127_2624617_23 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000002293 166.0
HFD3_k127_2624617_24 Endoribonuclease that initiates mRNA decay K18682 - - 0.0000000000000000000000000000000001892 133.0
HFD3_k127_2624617_25 metal-dependent membrane protease - - - 0.000000000000000000000000000000003978 141.0
HFD3_k127_2624617_26 RDD family - - - 0.000000000000000000000000000001096 128.0
HFD3_k127_2624617_27 PFAM Divergent PAP2 family K09775 - - 0.000000000000000000000000000002115 139.0
HFD3_k127_2624617_28 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000003444 102.0
HFD3_k127_2624617_29 protein conserved in bacteria - - - 0.0000000000000000001044 104.0
HFD3_k127_2624617_3 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 517.0
HFD3_k127_2624617_30 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - 0.0000000000004947 76.0
HFD3_k127_2624617_31 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000009159 60.0
HFD3_k127_2624617_33 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.000001715 61.0
HFD3_k127_2624617_34 protein conserved in bacteria - - - 0.0003313 51.0
HFD3_k127_2624617_4 Belongs to the glycosyl hydrolase 57 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 471.0
HFD3_k127_2624617_5 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 471.0
HFD3_k127_2624617_6 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 432.0
HFD3_k127_2624617_7 helicase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 432.0
HFD3_k127_2624617_8 Domains REC, sigma54 interaction, HTH8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 419.0
HFD3_k127_2624617_9 PFAM Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007894 366.0
HFD3_k127_2668656_0 ligase activity, forming nitrogen-metal bonds K02230 - 6.6.1.2 0.0 1386.0
HFD3_k127_2668656_1 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 1.066e-236 777.0
HFD3_k127_2668656_10 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 523.0
HFD3_k127_2668656_11 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006244 485.0
HFD3_k127_2668656_12 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 504.0
HFD3_k127_2668656_13 phosphorelay sensor kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 446.0
HFD3_k127_2668656_14 Biotin carboxylase C-terminal domain K01941,K01961 - 6.3.4.14,6.3.4.6,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 439.0
HFD3_k127_2668656_15 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 399.0
HFD3_k127_2668656_16 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 385.0
HFD3_k127_2668656_17 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008465 398.0
HFD3_k127_2668656_18 Alanine dehydrogenase/PNT, C-terminal domain K07538 - 1.1.1.368 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 376.0
HFD3_k127_2668656_19 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008103 376.0
HFD3_k127_2668656_2 Amylo-alpha-1,6-glucosidase - - - 1.173e-236 753.0
HFD3_k127_2668656_20 beta-glucosidase activity K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 376.0
HFD3_k127_2668656_21 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009652 364.0
HFD3_k127_2668656_22 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 354.0
HFD3_k127_2668656_23 PFAM ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 352.0
HFD3_k127_2668656_24 SMART Metal-dependent phosphohydrolase, HD region K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 341.0
HFD3_k127_2668656_25 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 319.0
HFD3_k127_2668656_26 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 316.0
HFD3_k127_2668656_27 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 325.0
HFD3_k127_2668656_28 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000158 275.0
HFD3_k127_2668656_29 Putative adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005904 264.0
HFD3_k127_2668656_3 choline dehydrogenase activity - - - 2.533e-234 744.0
HFD3_k127_2668656_30 spore germination - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007001 252.0
HFD3_k127_2668656_31 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007916 260.0
HFD3_k127_2668656_32 Belongs to the enoyl-CoA hydratase isomerase family K13766 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000003247 244.0
HFD3_k127_2668656_33 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.0000000000000000000000000000000000000000000000000000000002455 223.0
HFD3_k127_2668656_34 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000001761 205.0
HFD3_k127_2668656_35 - - - - 0.000000000000000000000000000000000000000000000000000001421 202.0
HFD3_k127_2668656_36 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000003951 212.0
HFD3_k127_2668656_37 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000001236 216.0
HFD3_k127_2668656_38 Sigma-70, region 4 K03088 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.00000000000000000000000000000000000000000000000000003417 211.0
HFD3_k127_2668656_39 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000000004368 186.0
HFD3_k127_2668656_4 cystathionine gamma-synthase activity K01739,K01740,K01760,K01761 - 2.5.1.48,2.5.1.49,4.4.1.11,4.4.1.8 1.91e-200 635.0
HFD3_k127_2668656_40 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000137 186.0
HFD3_k127_2668656_41 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.000000000000000000000000000000000000000000000003013 183.0
HFD3_k127_2668656_42 endonuclease activity K07451 - - 0.00000000000000000000000000000000000000000000003774 186.0
HFD3_k127_2668656_43 - - - - 0.00000000000000000000000000000000000000000001256 169.0
HFD3_k127_2668656_44 YHS domain - - - 0.00000000000000000000000000000000000000000001509 166.0
HFD3_k127_2668656_45 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K01950 - 6.3.5.1 0.00000000000000000000000000000000000000000008396 170.0
HFD3_k127_2668656_46 uridine kinase K00876 - 2.7.1.48 0.0000000000000000000000000000000000000000001064 171.0
HFD3_k127_2668656_47 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000008263 154.0
HFD3_k127_2668656_48 Cupin 2, conserved barrel domain protein K11477 - - 0.0000000000000000000000000000000000003933 146.0
HFD3_k127_2668656_49 Cupin 2, conserved barrel domain protein K11477 - - 0.0000000000000000000000000000000001214 150.0
HFD3_k127_2668656_5 PFAM PKD domain containing protein - - - 9.583e-198 651.0
HFD3_k127_2668656_50 Recombination protein O C terminal K03584 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000489 134.0
HFD3_k127_2668656_51 Protein of unknown function, DUF393 - - - 0.000000000000000000000000000001181 135.0
HFD3_k127_2668656_52 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000007899 127.0
HFD3_k127_2668656_53 lyase activity - - - 0.00000000000000000000000000003782 135.0
HFD3_k127_2668656_54 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000000000000000000009371 117.0
HFD3_k127_2668656_55 Tellurite resistance protein TerB - - - 0.00000000000000000000002264 108.0
HFD3_k127_2668656_56 Carbamoyl-phosphate synthetase large chain domain protein K01968 - 6.4.1.4 0.0000000000000000000001279 105.0
HFD3_k127_2668656_57 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000001346 101.0
HFD3_k127_2668656_58 Putative adhesin - - - 0.000000000000000000006197 108.0
HFD3_k127_2668656_59 PFAM Pentapeptide - - - 0.00000000000000000002682 101.0
HFD3_k127_2668656_6 gluconolactonase activity K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006498 610.0
HFD3_k127_2668656_61 Electron transfer DM13 - - - 0.000000000000001116 87.0
HFD3_k127_2668656_62 - - - - 0.000000000000006587 87.0
HFD3_k127_2668656_63 DinB family - - - 0.0000000000000209 87.0
HFD3_k127_2668656_65 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000007833 66.0
HFD3_k127_2668656_7 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009905 587.0
HFD3_k127_2668656_8 alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 534.0
HFD3_k127_2668656_9 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 554.0
HFD3_k127_2719963_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1107.0
HFD3_k127_2719963_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0 1080.0
HFD3_k127_2719963_10 Peptidyl arginine deiminase, type IV K01481 GO:0003674,GO:0003824,GO:0004668,GO:0005488,GO:0005509,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006082,GO:0006323,GO:0006325,GO:0006333,GO:0006334,GO:0006338,GO:0006464,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016043,GO:0016054,GO:0016569,GO:0016570,GO:0016597,GO:0016787,GO:0016810,GO:0016813,GO:0016990,GO:0018101,GO:0018193,GO:0018195,GO:0019538,GO:0019546,GO:0019752,GO:0019827,GO:0022607,GO:0031406,GO:0031497,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032991,GO:0034618,GO:0034622,GO:0034728,GO:0036094,GO:0036211,GO:0036413,GO:0036414,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044267,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0046872,GO:0046983,GO:0051276,GO:0065003,GO:0065004,GO:0070013,GO:0071103,GO:0071704,GO:0071824,GO:0071840,GO:0098727,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.3.15 0.000000000000000000000000000007925 139.0
HFD3_k127_2719963_11 response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.000000000000000000000000000222 130.0
HFD3_k127_2719963_12 PTS system, fructose subfamily K02768,K02769,K02770 - 2.7.1.202 0.0000000000000000000000001123 113.0
HFD3_k127_2719963_13 HNH nucleases - - - 0.000000000000000000000009416 108.0
HFD3_k127_2719963_14 Bacterial Ig-like domain (group 1) - - - 0.000000000000000003646 100.0
HFD3_k127_2719963_15 Putative phosphatase (DUF442) - - - 0.000000000000003314 86.0
HFD3_k127_2719963_16 methylamine metabolic process - - - 0.000000000000004752 85.0
HFD3_k127_2719963_17 - - - - 0.00000000001457 71.0
HFD3_k127_2719963_18 Rhodanese Homology Domain - - - 0.0000000004804 70.0
HFD3_k127_2719963_19 antisigma factor binding - - - 0.0000000005634 70.0
HFD3_k127_2719963_2 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 555.0
HFD3_k127_2719963_20 N-acetylmuramoyl-L-alanine amidase - - - 0.0000000008541 72.0
HFD3_k127_2719963_21 - - - - 0.00000007 65.0
HFD3_k127_2719963_22 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000001369 65.0
HFD3_k127_2719963_23 Peptidyl arginine deiminase, type II K01481 GO:0000323,GO:0000785,GO:0001672,GO:0001775,GO:0001959,GO:0001960,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002682,GO:0002683,GO:0002685,GO:0002686,GO:0002688,GO:0002689,GO:0003674,GO:0003824,GO:0004668,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005829,GO:0006325,GO:0006338,GO:0006355,GO:0006464,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0006996,GO:0007154,GO:0007165,GO:0008134,GO:0008150,GO:0008152,GO:0009719,GO:0009725,GO:0009755,GO:0009889,GO:0009891,GO:0009893,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010646,GO:0010648,GO:0010848,GO:0012505,GO:0014070,GO:0016043,GO:0016192,GO:0016569,GO:0016570,GO:0016787,GO:0016810,GO:0016813,GO:0018101,GO:0018193,GO:0018195,GO:0019219,GO:0019222,GO:0019538,GO:0023051,GO:0023052,GO:0023057,GO:0030141,GO:0030331,GO:0030334,GO:0030336,GO:0030518,GO:0030520,GO:0030522,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032101,GO:0032102,GO:0032870,GO:0032879,GO:0032940,GO:0033043,GO:0033044,GO:0033993,GO:0034097,GO:0034774,GO:0035257,GO:0035258,GO:0035327,GO:0035578,GO:0036211,GO:0036230,GO:0036413,GO:0036414,GO:0040012,GO:0040013,GO:0040029,GO:0042119,GO:0042221,GO:0042582,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043299,GO:0043312,GO:0043401,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044427,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0045815,GO:0045893,GO:0045935,GO:0046903,GO:0048096,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048545,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0050920,GO:0050922,GO:0051128,GO:0051171,GO:0051173,GO:0051179,GO:0051234,GO:0051252,GO:0051254,GO:0051270,GO:0051271,GO:0051276,GO:0051427,GO:0051716,GO:0060205,GO:0060255,GO:0060759,GO:0060761,GO:0065007,GO:0070013,GO:0070099,GO:0070100,GO:0070887,GO:0071310,GO:0071345,GO:0071383,GO:0071396,GO:0071407,GO:0071495,GO:0071704,GO:0071840,GO:0080090,GO:0097708,GO:0099503,GO:1901564,GO:1901623,GO:1901624,GO:1902275,GO:1902680,GO:1903506,GO:1903508,GO:1990823,GO:1990830,GO:2000112,GO:2000145,GO:2000146,GO:2000401,GO:2000402,GO:2001141 3.5.3.15 0.000006835 60.0
HFD3_k127_2719963_24 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00001292 57.0
HFD3_k127_2719963_3 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K01501 - 3.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 327.0
HFD3_k127_2719963_4 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002117 264.0
HFD3_k127_2719963_5 Pfam:Pyridox_oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001756 242.0
HFD3_k127_2719963_6 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000004653 238.0
HFD3_k127_2719963_7 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000004335 193.0
HFD3_k127_2719963_8 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000001521 199.0
HFD3_k127_2719963_9 Outer membrane protein beta-barrel family K16087 - - 0.0000000000000000000000000000000000000000000001366 192.0
HFD3_k127_2781235_0 PhoQ Sensor K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000009095 235.0
HFD3_k127_2781235_1 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000002443 221.0
HFD3_k127_2781235_2 Divergent polysaccharide deacetylase K09798 - - 0.00000000000000002908 94.0
HFD3_k127_2781235_4 HNH nucleases - - - 0.000002436 52.0
HFD3_k127_2781623_0 Domain in cystathionine beta-synthase and other proteins. - - - 1.097e-201 659.0
HFD3_k127_2781623_1 Alpha-2-Macroglobulin K06894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006022 596.0
HFD3_k127_2781623_10 Putative esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 317.0
HFD3_k127_2781623_11 Belongs to the peptidase S51 family - - - 0.000000000000000000000000000000000000000000000000000000000223 223.0
HFD3_k127_2781623_12 succinylglutamate desuccinylase activity K05526 - 3.5.1.96 0.000000000000000000000000000000000000000000000000000000000974 225.0
HFD3_k127_2781623_13 DNA-templated transcription, initiation - - - 0.00000000000000000000000000000000000000000000000000000007969 209.0
HFD3_k127_2781623_14 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000002363 173.0
HFD3_k127_2781623_15 Glyoxal oxidase N-terminus - - - 0.00000000000000000000000000000000000000000001943 188.0
HFD3_k127_2781623_16 Protein of unknown function (DUF1428) - - - 0.000000000000000000000000000000000000000001327 159.0
HFD3_k127_2781623_17 Uncharacterized conserved protein (DUF2277) - - - 0.000000000000000000000000000000005023 132.0
HFD3_k127_2781623_18 PFAM VanW family protein - - - 0.0000000000000000000000000000008401 132.0
HFD3_k127_2781623_19 CAAX protease self-immunity - - - 0.00000000000000000002667 100.0
HFD3_k127_2781623_2 Belongs to the GarS family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005476 571.0
HFD3_k127_2781623_20 Transmembrane protein 260 - - - 0.00000000000000003192 87.0
HFD3_k127_2781623_21 FlgD Ig-like domain - - - 0.0000000000002743 83.0
HFD3_k127_2781623_22 domain, Protein - - - 0.00000001947 69.0
HFD3_k127_2781623_23 HNH nucleases - - - 0.000001866 52.0
HFD3_k127_2781623_24 ferrous iron binding K06990,K09141 - - 0.00001309 58.0
HFD3_k127_2781623_3 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 509.0
HFD3_k127_2781623_4 cytochrome P450 K00493 - 1.14.14.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 502.0
HFD3_k127_2781623_5 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 486.0
HFD3_k127_2781623_6 Putative esterase K07214 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 444.0
HFD3_k127_2781623_7 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000547 407.0
HFD3_k127_2781623_8 ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005739 384.0
HFD3_k127_2781623_9 dihydrofolate reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006312 332.0
HFD3_k127_284844_0 Belongs to the ClpA ClpB family K03695,K03696 - - 9.509e-317 993.0
HFD3_k127_284844_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.555e-232 739.0
HFD3_k127_284844_10 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006123 341.0
HFD3_k127_284844_11 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 326.0
HFD3_k127_284844_12 COGs COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 317.0
HFD3_k127_284844_13 Catalyzes the specific phosphorylation of arginine residues in proteins K19405 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 321.0
HFD3_k127_284844_14 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009099 323.0
HFD3_k127_284844_15 ABC-type transport system involved in lipoprotein release permease component K02004,K09808 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0098796,GO:0098797,GO:1990778 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 319.0
HFD3_k127_284844_16 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009311 305.0
HFD3_k127_284844_17 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000002244 269.0
HFD3_k127_284844_18 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000003204 264.0
HFD3_k127_284844_19 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000002295 244.0
HFD3_k127_284844_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 594.0
HFD3_k127_284844_20 MotA/TolQ/ExbB proton channel family K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000003032 230.0
HFD3_k127_284844_21 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.00000000000000000000000000000000000000000000000000000000003618 229.0
HFD3_k127_284844_22 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000004707 204.0
HFD3_k127_284844_23 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000005474 204.0
HFD3_k127_284844_24 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000001432 188.0
HFD3_k127_284844_25 Domain of unknown function (DUF374) K02527,K09778 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000001544 192.0
HFD3_k127_284844_26 protein with conserved CXXC pairs K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 - 0.000000000000000000000000000000000000003201 157.0
HFD3_k127_284844_27 hydrolase, HAD-superfamily, subfamily IIIA K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000003654 167.0
HFD3_k127_284844_28 PFAM Biopolymer transport protein ExbD TolR - - - 0.000000000000000000000000000000000002006 143.0
HFD3_k127_284844_29 PFAM glycosyl transferase family 9 K02843 - - 0.00000000000000000000000000000001069 148.0
HFD3_k127_284844_3 Asparaginyl-tRNA synthetase K01893 GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 550.0
HFD3_k127_284844_30 biopolymer transport protein - - - 0.00000000000000000000000000000007581 130.0
HFD3_k127_284844_31 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000003328 136.0
HFD3_k127_284844_32 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000316 127.0
HFD3_k127_284844_33 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000000000000000000000002612 125.0
HFD3_k127_284844_34 TIGRFAM phosphate binding protein K02040 - - 0.0000000000000000000000003577 117.0
HFD3_k127_284844_35 Outer membrane efflux protein K12340 - - 0.0000000000000000000002968 111.0
HFD3_k127_284844_36 - - - - 0.00000000000000000005853 106.0
HFD3_k127_284844_37 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000000000006731 84.0
HFD3_k127_284844_38 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000001319 91.0
HFD3_k127_284844_39 tetratricopeptide repeat - - - 0.000000000000001968 90.0
HFD3_k127_284844_4 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 517.0
HFD3_k127_284844_40 unfolded protein binding K06142 - - 0.000000000001157 79.0
HFD3_k127_284844_41 Yip1 domain - - - 0.000002192 58.0
HFD3_k127_284844_42 Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) - - - 0.000002452 55.0
HFD3_k127_284844_43 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00001226 59.0
HFD3_k127_284844_5 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006107 524.0
HFD3_k127_284844_6 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 514.0
HFD3_k127_284844_7 ABC transporter K02021,K06147,K06148,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 506.0
HFD3_k127_284844_8 Surface antigen K07277 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 446.0
HFD3_k127_284844_9 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02372,K02535,K13599,K16363 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171 3.5.1.108,4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 401.0
HFD3_k127_287515_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.0 1190.0
HFD3_k127_287515_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00262 - 1.4.1.4 1.279e-245 766.0
HFD3_k127_287515_10 Nitronate monooxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 434.0
HFD3_k127_287515_11 ATP-grasp domain K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 394.0
HFD3_k127_287515_12 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 372.0
HFD3_k127_287515_13 Serine threonine protein kinase involved in cell cycle control - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 358.0
HFD3_k127_287515_14 peptidase activity, acting on L-amino acid peptides K07004,K09955 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007269 368.0
HFD3_k127_287515_15 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 294.0
HFD3_k127_287515_16 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002854 267.0
HFD3_k127_287515_17 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000003609 271.0
HFD3_k127_287515_18 UPF0114 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000002771 238.0
HFD3_k127_287515_19 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001768 244.0
HFD3_k127_287515_2 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 1.075e-199 638.0
HFD3_k127_287515_20 xylanase chitin deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000179 253.0
HFD3_k127_287515_21 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000001203 245.0
HFD3_k127_287515_22 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703,K20452 - 4.2.1.33,4.2.1.35,4.2.1.85 0.00000000000000000000000000000000000000000000000000000000000000004637 250.0
HFD3_k127_287515_23 SMART Tetratricopeptide domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000005119 243.0
HFD3_k127_287515_24 MOSC domain - - - 0.0000000000000000000000000000000000000000000000002049 184.0
HFD3_k127_287515_25 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.000000000000000000000000000000000000000000000001 201.0
HFD3_k127_287515_26 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000002397 175.0
HFD3_k127_287515_27 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000002298 175.0
HFD3_k127_287515_28 PFAM Dual specificity protein phosphatase - - - 0.0000000000000000000000000000000000000000002896 163.0
HFD3_k127_287515_29 Lysophospholipase K01048 - 3.1.1.5 0.000000000000000000000000000000000000000004202 173.0
HFD3_k127_287515_3 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 1.161e-199 644.0
HFD3_k127_287515_30 Protein of unknown function (DUF3037) - - - 0.00000000000000000000000000000000000000008063 163.0
HFD3_k127_287515_31 YceI-like domain - - - 0.0000000000000000000000000000000000000003565 160.0
HFD3_k127_287515_32 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000007926 156.0
HFD3_k127_287515_33 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000000000000000000000001404 170.0
HFD3_k127_287515_34 EVE domain - - - 0.0000000000000000000000000000000000001715 145.0
HFD3_k127_287515_35 Domain of unknown function (DUF4442) - - - 0.0000000000000000000000000000000000002837 153.0
HFD3_k127_287515_36 beta-N-acetylhexosaminidase activity - - - 0.000000000000000000000000000000002794 149.0
HFD3_k127_287515_37 - - - - 0.000000000000000000000000002206 125.0
HFD3_k127_287515_38 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000425 127.0
HFD3_k127_287515_39 amine dehydrogenase activity - - - 0.000000000000000000001402 112.0
HFD3_k127_287515_4 Dehydrogenase E1 component K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 593.0
HFD3_k127_287515_40 Galactose oxidase, central domain - - - 0.000000000000000000002943 110.0
HFD3_k127_287515_41 Thioredoxin-like - - - 0.000000000000000000004558 108.0
HFD3_k127_287515_42 Protein of unknown function, DUF547 - - - 0.000000000000000009173 99.0
HFD3_k127_287515_43 Bacterial transferase hexapeptide (six repeats) K00638 - 2.3.1.28 0.00000000000000002006 95.0
HFD3_k127_287515_44 cellulose binding K00505 - 1.14.18.1 0.00000000000000003773 97.0
HFD3_k127_287515_45 TIGRFAM RHS repeat-associated core domain - - - 0.00000000000000008624 96.0
HFD3_k127_287515_47 protein import - - - 0.000000000000005618 87.0
HFD3_k127_287515_48 Tetratricopeptide repeat - - - 0.0000000000002966 83.0
HFD3_k127_287515_49 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000001042 82.0
HFD3_k127_287515_5 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 561.0
HFD3_k127_287515_50 Involved in the tonB-independent uptake of proteins - - - 0.000000000002556 80.0
HFD3_k127_287515_51 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00658 - 2.3.1.61 0.000000000003118 79.0
HFD3_k127_287515_52 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000274 76.0
HFD3_k127_287515_53 peptidyl-tyrosine sulfation - - - 0.0000000003097 73.0
HFD3_k127_287515_54 Belongs to the glycosyl hydrolase 13 family - - - 0.000000008916 70.0
HFD3_k127_287515_55 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000008822 63.0
HFD3_k127_287515_56 Belongs to the glycosyl hydrolase 13 family - - - 0.000006538 59.0
HFD3_k127_287515_57 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0009559 51.0
HFD3_k127_287515_58 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol - - - 0.0009727 52.0
HFD3_k127_287515_59 COG3209 Rhs family protein - - - 0.0009993 52.0
HFD3_k127_287515_6 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 519.0
HFD3_k127_287515_7 DNA polymerase beta thumb K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000872 533.0
HFD3_k127_287515_8 Dehydrogenase K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 524.0
HFD3_k127_287515_9 Putative zinc-binding metallo-peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 461.0
HFD3_k127_2930145_0 Major Facilitator Superfamily K02445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007104 606.0
HFD3_k127_2930145_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 651.0
HFD3_k127_2930145_10 Pfam:PNPOx_C K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000000000000000000004058 224.0
HFD3_k127_2930145_11 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000003377 216.0
HFD3_k127_2930145_12 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000000000000000001577 191.0
HFD3_k127_2930145_13 Serine phosphatase RsbU regulator of sigma subunit K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000218 189.0
HFD3_k127_2930145_14 Histidine kinase - - - 0.00000000000000000000000000000000000000000005075 174.0
HFD3_k127_2930145_15 Autotransporter beta-domain - - - 0.00000000000000000000000000000000000000024 175.0
HFD3_k127_2930145_16 response regulator receiver - - - 0.0000000000000000000000000000000000000009211 168.0
HFD3_k127_2930145_17 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000001357 154.0
HFD3_k127_2930145_18 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000003494 130.0
HFD3_k127_2930145_19 - - - - 0.00000000000000000000000000003048 129.0
HFD3_k127_2930145_2 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 450.0
HFD3_k127_2930145_20 - - - - 0.000000000000000000000000002513 116.0
HFD3_k127_2930145_21 Histidine kinase - - - 0.000000000000000000000000004325 129.0
HFD3_k127_2930145_22 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000006982 128.0
HFD3_k127_2930145_23 rieske 2fe-2s - - - 0.0000000000000000000000009251 109.0
HFD3_k127_2930145_24 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000001692 111.0
HFD3_k127_2930145_25 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.0000000000000000000002038 114.0
HFD3_k127_2930145_26 PEP-CTERM motif - - - 0.000000000000002734 87.0
HFD3_k127_2930145_27 Evidence 5 No homology to any previously reported sequences - - - 0.000000000001216 83.0
HFD3_k127_2930145_28 COG COG3210 Large exoproteins involved in heme utilization or adhesion - - - 0.00000001826 69.0
HFD3_k127_2930145_29 - - - - 0.0000000233 69.0
HFD3_k127_2930145_3 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 411.0
HFD3_k127_2930145_30 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.0000002673 63.0
HFD3_k127_2930145_31 - - - - 0.00004989 52.0
HFD3_k127_2930145_32 Cytochrome c - - - 0.00007072 56.0
HFD3_k127_2930145_4 Aminotransferase class-V K01556 - 3.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008596 381.0
HFD3_k127_2930145_5 PFAM Thiamine pyrophosphate K00170,K00187 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 372.0
HFD3_k127_2930145_6 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 356.0
HFD3_k127_2930145_7 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 292.0
HFD3_k127_2930145_8 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006013 299.0
HFD3_k127_2930145_9 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000005806 243.0
HFD3_k127_298145_0 COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K04108 - 1.3.7.9 9.368e-254 815.0
HFD3_k127_298145_1 Fructose-bisphosphate aldolase class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006492 491.0
HFD3_k127_298145_10 CcmB protein K02193,K02194 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.41 0.000000000000000000000000000000000000000001668 164.0
HFD3_k127_298145_11 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000003031 142.0
HFD3_k127_298145_12 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000004843 115.0
HFD3_k127_298145_13 - - - - 0.000000000001109 71.0
HFD3_k127_298145_14 ABC transporter K16013 - - 0.000000003413 61.0
HFD3_k127_298145_15 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000003454 66.0
HFD3_k127_298145_2 Cytochrome C assembly protein K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 464.0
HFD3_k127_298145_3 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 421.0
HFD3_k127_298145_4 impB/mucB/samB family K02346,K03502 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 296.0
HFD3_k127_298145_5 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000002643 284.0
HFD3_k127_298145_6 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001745 247.0
HFD3_k127_298145_7 Cytochrome C assembly protein K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.000000000000000000000000000000000000000000000000000000000000004519 224.0
HFD3_k127_298145_8 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000253 191.0
HFD3_k127_298145_9 FAD dependent oxidoreductase K09471 - - 0.000000000000000000000000000000000000000000000008699 189.0
HFD3_k127_3013939_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 9.898e-258 816.0
HFD3_k127_3013939_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 1.198e-208 693.0
HFD3_k127_3013939_10 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 384.0
HFD3_k127_3013939_11 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 401.0
HFD3_k127_3013939_12 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 377.0
HFD3_k127_3013939_13 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 348.0
HFD3_k127_3013939_14 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001093 286.0
HFD3_k127_3013939_15 peptidyl-lysine modification to peptidyl-hypusine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005062 295.0
HFD3_k127_3013939_16 Permease YjgP YjgQ family protein K07091,K11720 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003906 284.0
HFD3_k127_3013939_17 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000001809 284.0
HFD3_k127_3013939_18 Enoyl-(Acyl carrier protein) reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000001333 268.0
HFD3_k127_3013939_19 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000009758 273.0
HFD3_k127_3013939_2 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006341 591.0
HFD3_k127_3013939_20 Peptidase M28 - - - 0.00000000000000000000000000000000000000000000000000000000000001312 231.0
HFD3_k127_3013939_21 mannose-ethanolamine phosphotransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000004067 239.0
HFD3_k127_3013939_22 Riboflavin kinase K11753 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000009549 227.0
HFD3_k127_3013939_23 Glycosyl transferase family 2 K00721,K00786 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000001633 215.0
HFD3_k127_3013939_24 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000000000000000000000000000001674 208.0
HFD3_k127_3013939_25 Permease YjgP YjgQ K11720 - - 0.0000000000000000000000000000000000000000000000000008358 209.0
HFD3_k127_3013939_26 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000000000000005238 192.0
HFD3_k127_3013939_27 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000000000001018 191.0
HFD3_k127_3013939_28 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000001283 173.0
HFD3_k127_3013939_29 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000001364 185.0
HFD3_k127_3013939_3 Belongs to the aldehyde dehydrogenase family K22187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 566.0
HFD3_k127_3013939_30 Glycosyl transferases group 1 K19424 - - 0.0000000000000000000000000000000000000000000002572 194.0
HFD3_k127_3013939_31 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000002587 171.0
HFD3_k127_3013939_32 ECF sigma factor K03088 - - 0.000000000000000000000000000000000009865 144.0
HFD3_k127_3013939_33 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000004929 155.0
HFD3_k127_3013939_34 Acetyl-CoA carboxylase, biotin carboxyl carrier protein K01571,K01960 - 4.1.1.3,6.4.1.1 0.0000000000000000000000000000000005244 141.0
HFD3_k127_3013939_35 3-beta hydroxysteroid dehydrogenase K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000006127 151.0
HFD3_k127_3013939_36 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000185 146.0
HFD3_k127_3013939_37 Belongs to the ComB family K05979 - 3.1.3.71 0.000000000000000000000000000000002003 141.0
HFD3_k127_3013939_38 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000406 128.0
HFD3_k127_3013939_39 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000001185 124.0
HFD3_k127_3013939_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005087 531.0
HFD3_k127_3013939_40 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000001833 111.0
HFD3_k127_3013939_41 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000001827 102.0
HFD3_k127_3013939_42 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000231 117.0
HFD3_k127_3013939_43 Protein of unknown function (DUF503) K09764 - - 0.00000000000000000006367 93.0
HFD3_k127_3013939_44 acr, cog1399 K07040 - - 0.0000000000000000001413 95.0
HFD3_k127_3013939_45 Ribosomal L32p protein family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.000000000000000002332 87.0
HFD3_k127_3013939_46 PFAM polysaccharide export protein K01991 - - 0.00000000000000005638 92.0
HFD3_k127_3013939_47 Polysaccharide biosynthesis protein - - - 0.000000000000002974 89.0
HFD3_k127_3013939_48 Uncharacterized conserved protein (DUF2304) K09153 - - 0.000000000002318 72.0
HFD3_k127_3013939_49 protein tyrosine kinase activity - - - 0.000000000009933 79.0
HFD3_k127_3013939_5 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 549.0
HFD3_k127_3013939_50 Polysaccharide biosynthesis protein K03328 - - 0.0000000001386 75.0
HFD3_k127_3013939_51 Polysaccharide biosynthesis protein - - - 0.000000000874 71.0
HFD3_k127_3013939_52 - - - - 0.000001141 60.0
HFD3_k127_3013939_53 G-rich domain on putative tyrosine kinase K16554 - - 0.000001256 62.0
HFD3_k127_3013939_54 Putative zinc-finger - - - 0.000005587 58.0
HFD3_k127_3013939_6 Participates in both transcription termination and antitermination K02600 GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 429.0
HFD3_k127_3013939_7 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 428.0
HFD3_k127_3013939_8 PFAM Type II secretion system protein E K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006006 410.0
HFD3_k127_3013939_9 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 407.0
HFD3_k127_3065426_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.142e-277 884.0
HFD3_k127_3065426_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 570.0
HFD3_k127_3065426_2 Aminotransferase class-V - GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 322.0
HFD3_k127_3065426_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 301.0
HFD3_k127_3065426_4 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000005788 177.0
HFD3_k127_3065426_7 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000001269 74.0
HFD3_k127_3065426_8 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.0002061 44.0
HFD3_k127_3075826_0 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000005378 201.0
HFD3_k127_3075826_1 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.0000000000000000000000000000000000000000000000006801 187.0
HFD3_k127_3075826_2 6-pyruvoyl tetrahydropterin synthase K01737 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0070497,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000001083 158.0
HFD3_k127_3075826_3 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000988 125.0
HFD3_k127_3075826_4 CAAX protease self-immunity - - - 0.0008956 50.0
HFD3_k127_3116878_0 FAD linked oxidase domain protein - - - 2.227e-194 618.0
HFD3_k127_3116878_1 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 449.0
HFD3_k127_3116878_3 - - - - 0.0007265 53.0
HFD3_k127_3174019_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008084 389.0
HFD3_k127_3174019_1 Domain of unknown function (DUF1998) K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005829 383.0
HFD3_k127_3174019_10 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005494 301.0
HFD3_k127_3174019_11 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004491 283.0
HFD3_k127_3174019_12 Metallopeptidase family M24 K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000003452 274.0
HFD3_k127_3174019_13 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001911 269.0
HFD3_k127_3174019_14 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000337 263.0
HFD3_k127_3174019_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000001237 218.0
HFD3_k127_3174019_16 PFAM Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000001501 218.0
HFD3_k127_3174019_17 Dienelactone hydrolase family K06999 - - 0.000000000000000000000000000000000000000000000000000000000002269 229.0
HFD3_k127_3174019_18 - - - - 0.00000000000000000000000000000000000000000000000000000000000752 227.0
HFD3_k127_3174019_19 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000001247 213.0
HFD3_k127_3174019_2 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 382.0
HFD3_k127_3174019_20 - - - - 0.00000000000000000000000000000000000000000000000004689 199.0
HFD3_k127_3174019_22 domain protein K01179,K02238,K20276 - 3.2.1.4 0.0000000000000000000000000000000000000000000000811 192.0
HFD3_k127_3174019_23 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000009037 168.0
HFD3_k127_3174019_24 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.0000000000000000000000000000000000009076 143.0
HFD3_k127_3174019_25 Belongs to the glycosyl hydrolase 32 family K01193 - 3.2.1.26 0.000000000000000000000000000000000001079 158.0
HFD3_k127_3174019_26 HAD-superfamily hydrolase, subfamily IA, variant 1 K07025 - - 0.000000000000000000000000000000000035 143.0
HFD3_k127_3174019_27 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.0000000000000000000000000000000001483 143.0
HFD3_k127_3174019_28 glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000001823 147.0
HFD3_k127_3174019_29 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000002503 143.0
HFD3_k127_3174019_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 360.0
HFD3_k127_3174019_30 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000000000005429 144.0
HFD3_k127_3174019_31 - - - - 0.0000000000000000000000000009017 131.0
HFD3_k127_3174019_32 - - - - 0.0000000000000000000000001565 108.0
HFD3_k127_3174019_33 Transport and Golgi organisation 2 - - - 0.0000000000000000007741 96.0
HFD3_k127_3174019_34 amine dehydrogenase activity K01126,K20276 - 3.1.4.46 0.0000000000000005233 94.0
HFD3_k127_3174019_35 - - - - 0.00000000000302 79.0
HFD3_k127_3174019_36 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000008952 63.0
HFD3_k127_3174019_37 Endonuclease I - - - 0.00004628 57.0
HFD3_k127_3174019_38 Flagellar hook capping protein - N-terminal region K02389 - - 0.00009014 57.0
HFD3_k127_3174019_39 Belongs to the UDP-glycosyltransferase family K08237,K12338,K13692,K21371,K21374 GO:0000278,GO:0000280,GO:0000281,GO:0000910,GO:0000911,GO:0000919,GO:0001101,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0008150,GO:0008152,GO:0008194,GO:0009072,GO:0009524,GO:0009719,GO:0009725,GO:0009751,GO:0009832,GO:0009920,GO:0009987,GO:0010033,GO:0012505,GO:0014070,GO:0016043,GO:0016740,GO:0016757,GO:0016758,GO:0019752,GO:0022402,GO:0022607,GO:0032506,GO:0032787,GO:0035251,GO:0042221,GO:0042493,GO:0042537,GO:0042546,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046482,GO:0046527,GO:0046677,GO:0048285,GO:0050896,GO:0051301,GO:0061640,GO:0071554,GO:0071669,GO:0071704,GO:0071840,GO:0080002,GO:0080018,GO:0080043,GO:0080044,GO:0140014,GO:1901360,GO:1901564,GO:1901700,GO:1902410,GO:1903047 2.4.1.121,2.4.1.218,2.4.1.271,2.4.1.298,2.4.1.324 0.0008715 51.0
HFD3_k127_3174019_4 glyoxalase bleomycin resistance protein dioxygenase K15975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 347.0
HFD3_k127_3174019_40 Fibronectin type 3 domain - - - 0.0009295 52.0
HFD3_k127_3174019_5 PKD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 346.0
HFD3_k127_3174019_6 COG2133 Glucose sorbosone dehydrogenases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009136 341.0
HFD3_k127_3174019_7 COG0577 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 327.0
HFD3_k127_3174019_8 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 336.0
HFD3_k127_3174019_9 PFAM Sodium sulphate symporter K14445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 301.0
HFD3_k127_321509_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 6.272e-229 736.0
HFD3_k127_321509_1 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 439.0
HFD3_k127_321509_10 GTP cyclohydrolase I K01495 - 3.5.4.16 0.00000000000000000000000000000002534 134.0
HFD3_k127_321509_11 alkyl hydroperoxide reductase K03387 - - 0.0000000000000000000000002117 122.0
HFD3_k127_321509_12 COG0463, glycosyltransferases involved in cell wall biogenesis - GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.000000000000000000004648 107.0
HFD3_k127_321509_13 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000008012 98.0
HFD3_k127_321509_14 protein secretion - - - 0.0000000001363 76.0
HFD3_k127_321509_15 Tetratricopeptide repeat - - - 0.0000005975 53.0
HFD3_k127_321509_16 SprB repeat - - - 0.00001779 58.0
HFD3_k127_321509_17 endonuclease activity K07451 - - 0.0003264 50.0
HFD3_k127_321509_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 351.0
HFD3_k127_321509_3 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 335.0
HFD3_k127_321509_4 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000766 310.0
HFD3_k127_321509_5 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004412 308.0
HFD3_k127_321509_6 Mannose-1-phosphate guanylyltransferase K00971 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000003918 256.0
HFD3_k127_321509_7 Sugar nucleotidyl transferase - - - 0.0000000000000000000000000000000000000000000000000000001729 217.0
HFD3_k127_321509_8 Protein of unknown function (DUF1810) - - - 0.000000000000000000000000000000000000000000000000000002579 194.0
HFD3_k127_321509_9 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000001359 182.0
HFD3_k127_3298031_0 4Fe-4S binding domain - - - 9.076e-256 809.0
HFD3_k127_3298031_1 PFAM GlcNAc-PI de-N-acetylase - - - 1.112e-230 741.0
HFD3_k127_3298031_10 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000006854 171.0
HFD3_k127_3298031_11 peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000007857 138.0
HFD3_k127_3298031_12 PFAM Cold-shock protein, DNA-binding K03704 - - 0.00000000000000000000000000034 116.0
HFD3_k127_3298031_13 - - - - 0.0000000000000000000000001386 121.0
HFD3_k127_3298031_14 Glycosyl hydrolases family 32 N-terminal domain K01193 - 3.2.1.26 0.00000000000000005474 96.0
HFD3_k127_3298031_15 FlgD Ig-like domain - - - 0.0000001984 63.0
HFD3_k127_3298031_16 cellulose binding - - - 0.000007939 59.0
HFD3_k127_3298031_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 595.0
HFD3_k127_3298031_3 PFAM Peptidase M29, aminopeptidase II K19689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 470.0
HFD3_k127_3298031_4 ABC transporter K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 441.0
HFD3_k127_3298031_5 Urate oxidase N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000663 359.0
HFD3_k127_3298031_6 BMC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002137 244.0
HFD3_k127_3298031_7 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000005045 239.0
HFD3_k127_3298031_8 Saccharopine dehydrogenase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000544 222.0
HFD3_k127_3298031_9 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000001104 186.0
HFD3_k127_341490_0 Helix-hairpin-helix motif K02237 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 368.0
HFD3_k127_341490_1 photosystem II stabilization K02237 - - 0.000000000000000000000000000000000003102 149.0
HFD3_k127_341490_2 long-chain fatty acid transport protein K06076 - - 0.000000000002045 81.0
HFD3_k127_341490_3 Metallo-beta-lactamase superfamily K02238 - - 0.000000007173 69.0
HFD3_k127_341490_4 Evidence 5 No homology to any previously reported sequences K07004 - - 0.00002745 58.0
HFD3_k127_3423391_0 phosphate acetyltransferase K00029,K00625,K13788 - 1.1.1.40,2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000001147 277.0
HFD3_k127_3423391_1 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000005949 172.0
HFD3_k127_3423391_2 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000000000000000000000002837 165.0
HFD3_k127_3423391_3 shikimate kinase activity K00891,K13829 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71,4.2.3.4 0.0000000000000000000000000000001021 131.0
HFD3_k127_3423391_4 Putative regulatory protein - - - 0.000000000000000000002109 96.0
HFD3_k127_3423391_5 Aconitase C-terminal domain K01681 - 4.2.1.3 0.0000000001481 73.0
HFD3_k127_3477434_0 TIGRFAM methylmalonyl-CoA mutase N-terminal domain K01848 - 5.4.99.2 2.927e-227 719.0
HFD3_k127_3477434_1 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009748 480.0
HFD3_k127_3477434_10 membrane - - - 0.0000000000000000000000000000000000000000000000000003102 207.0
HFD3_k127_3477434_11 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000006909 187.0
HFD3_k127_3477434_12 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000002732 165.0
HFD3_k127_3477434_14 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000006222 162.0
HFD3_k127_3477434_15 Glyoxalase-like domain K06996 - - 0.000000000000000000000000000000000001157 149.0
HFD3_k127_3477434_16 Flavodoxin-like fold - - - 0.0000000000000001118 90.0
HFD3_k127_3477434_17 COG0515 Serine threonine protein kinase - - - 0.0000006803 55.0
HFD3_k127_3477434_2 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 456.0
HFD3_k127_3477434_3 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 412.0
HFD3_k127_3477434_4 acyl-CoA dehydrogenase K00248,K22430 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0016628,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363 1.3.1.108,1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 423.0
HFD3_k127_3477434_5 acyl-CoA dehydrogenase K18244 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006877 385.0
HFD3_k127_3477434_6 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 386.0
HFD3_k127_3477434_7 ArgK protein K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009326 302.0
HFD3_k127_3477434_8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000005391 259.0
HFD3_k127_3477434_9 FIST C domain - GO:0008150,GO:0040007 - 0.00000000000000000000000000000000000000000000000000000000000000000003701 247.0
HFD3_k127_3599482_0 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 6.96e-196 659.0
HFD3_k127_3599482_1 PglZ domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009209 548.0
HFD3_k127_3599482_10 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000001235 121.0
HFD3_k127_3599482_11 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000000000005127 108.0
HFD3_k127_3599482_12 PFAM Peptidase M22, glycoprotease K14742 - - 0.0000000000001065 84.0
HFD3_k127_3599482_13 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.000001949 58.0
HFD3_k127_3599482_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006723 499.0
HFD3_k127_3599482_3 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744,K09774 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 378.0
HFD3_k127_3599482_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0042759,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007563 324.0
HFD3_k127_3599482_5 Integral membrane sensor signal transduction histidine kinase K07709,K13924 - 2.1.1.80,2.7.13.3,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000004656 274.0
HFD3_k127_3599482_6 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000977 231.0
HFD3_k127_3599482_7 Pyridoxal-phosphate dependent enzyme K01697 GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363 4.2.1.22 0.0000000000000000000000000000000000000000000000000000002524 199.0
HFD3_k127_3599482_8 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000001742 138.0
HFD3_k127_3599482_9 Tetratricopeptide repeat - - - 0.0000000000000000000000000258 123.0
HFD3_k127_3602117_0 Belongs to the aldehyde dehydrogenase family K00128,K00138 - 1.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 599.0
HFD3_k127_3602117_1 4-Hydroxyphenylpyruvate dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 584.0
HFD3_k127_3602117_10 Ribosomal protein L11 methyltransferase (PrmA) K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000001418 274.0
HFD3_k127_3602117_11 ABC 3 transport family K02075 - - 0.00000000000000000000000000000000000000000000000000000002599 218.0
HFD3_k127_3602117_12 Belongs to the bacterial solute-binding protein 9 family K02077 - - 0.00000000000000000000000000000000000000000000000000000003674 208.0
HFD3_k127_3602117_13 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000004827 211.0
HFD3_k127_3602117_14 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000002852 201.0
HFD3_k127_3602117_15 BioY family K03523 - - 0.00000000000000000000000000000000000000000000000004979 191.0
HFD3_k127_3602117_16 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000000000000002943 177.0
HFD3_k127_3602117_17 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000002339 165.0
HFD3_k127_3602117_18 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000000000000004671 132.0
HFD3_k127_3602117_19 DinB superfamily - - - 0.0000000000000000000000000001196 123.0
HFD3_k127_3602117_2 Pyridoxal-dependent decarboxylase conserved domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 559.0
HFD3_k127_3602117_20 - - - - 0.000000000000000000000000005583 115.0
HFD3_k127_3602117_21 3-carboxyethylcatechol 2,3-dioxygenase activity K00455,K15777 - 1.13.11.15 0.0000000000000000000000005393 119.0
HFD3_k127_3602117_22 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000007743 103.0
HFD3_k127_3602117_23 phosphate-selective porin O and P - - - 0.000000000000000000001322 111.0
HFD3_k127_3602117_24 Tetratricopeptide repeat - - - 0.000001077 61.0
HFD3_k127_3602117_25 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000001512 61.0
HFD3_k127_3602117_26 DinB superfamily - - - 0.00001526 54.0
HFD3_k127_3602117_27 COG0457 FOG TPR repeat - - - 0.00001778 53.0
HFD3_k127_3602117_28 DinB superfamily - - - 0.0001554 54.0
HFD3_k127_3602117_3 Bacterial Ig-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 417.0
HFD3_k127_3602117_4 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 378.0
HFD3_k127_3602117_5 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008325 365.0
HFD3_k127_3602117_6 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 368.0
HFD3_k127_3602117_7 PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 345.0
HFD3_k127_3602117_8 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 361.0
HFD3_k127_3602117_9 Creatinine amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 330.0
HFD3_k127_371744_0 ABC transporter - - - 1.01e-255 797.0
HFD3_k127_371744_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 2.328e-223 700.0
HFD3_k127_371744_10 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000529 213.0
HFD3_k127_371744_11 cytochrome c nitrite reductase K15876 - - 0.0000000000000000000000000000000000000000000000000001848 190.0
HFD3_k127_371744_2 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 553.0
HFD3_k127_371744_3 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 484.0
HFD3_k127_371744_4 Aldo/keto reductase family K05275 - 1.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009285 503.0
HFD3_k127_371744_5 SNF2 family N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 447.0
HFD3_k127_371744_6 Zn-dependent proteases and their inactivated homologs K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007149 365.0
HFD3_k127_371744_7 Nuclease, EndA NucM family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004748 283.0
HFD3_k127_371744_9 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000003141 203.0
HFD3_k127_3717870_0 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 387.0
HFD3_k127_3717870_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 300.0
HFD3_k127_3717870_2 Dimerisation domain of Zinc Transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009689 257.0
HFD3_k127_3717870_3 amine dehydrogenase activity K14647,K21449 - - 0.00000000000000000000000000000000008132 154.0
HFD3_k127_3717870_4 Immune inhibitor A peptidase M6 - - - 0.0000002973 64.0
HFD3_k127_371913_0 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007158 421.0
HFD3_k127_371913_1 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 323.0
HFD3_k127_371913_10 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.00002114 57.0
HFD3_k127_371913_2 polysaccharide export K01991 - - 0.000000000000000000000000000000000000000000000000008897 201.0
HFD3_k127_371913_3 Glycosyl transferase - - - 0.0000000000000000000000000000000000000000000000004514 187.0
HFD3_k127_371913_4 transferase activity, transferring glycosyl groups K00713,K03280 - 2.4.1.56 0.0000000000000000000000000000006715 135.0
HFD3_k127_371913_5 PFAM Glycosyl transferase family 2 K07011 - - 0.0000000000000000000000000003934 131.0
HFD3_k127_371913_6 Chain length determinant protein K01153,K05789,K07011,K16554 - 3.1.21.3 0.00000000000000000000000541 115.0
HFD3_k127_371913_7 Tetratricopeptide repeat - - - 0.000000000000000000002282 111.0
HFD3_k127_371913_8 -O-antigen K18814 - - 0.000002625 60.0
HFD3_k127_371913_9 Protein of unknown function, DUF255 K06888 - - 0.000004781 58.0
HFD3_k127_3751605_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006344 601.0
HFD3_k127_3751605_1 pyridine nucleotide-disulphide oxidoreductase dimerisation K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 414.0
HFD3_k127_3751605_10 FHA domain - - - 0.000000655 64.0
HFD3_k127_3751605_2 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001993 290.0
HFD3_k127_3751605_3 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000007522 211.0
HFD3_k127_3751605_4 Belongs to the peptidase S8 family K08651,K14743 - 3.4.21.66 0.0000000000000000000000000000000000000000000007469 184.0
HFD3_k127_3751605_5 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.0000000000000000000000000000002268 132.0
HFD3_k127_3751605_6 Lytic transglycosylase catalytic K08307 - - 0.0000000000000000000000004287 121.0
HFD3_k127_3751605_7 CHAT domain - - - 0.0000000000000003136 91.0
HFD3_k127_3751605_8 GGDEF domain - - - 0.00000000001211 78.0
HFD3_k127_3751605_9 Forkhead associated domain - - - 0.00000009409 64.0
HFD3_k127_3795695_0 Glutamine synthetase, catalytic region K01915 - 6.3.1.2 2.055e-255 809.0
HFD3_k127_3795695_1 Sodium:solute symporter family K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 351.0
HFD3_k127_3795695_2 Rhomboid family - - - 0.000000000000000000000000000000000000000000003963 175.0
HFD3_k127_3795695_3 TonB-dependent receptor K02014 - - 0.000000000000000000000000000000000229 152.0
HFD3_k127_3900999_0 Sodium/hydrogen exchanger family K03455 - - 8.525e-196 635.0
HFD3_k127_3900999_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005293 485.0
HFD3_k127_3900999_10 cellulose binding - - - 0.0000000000000000000000000000000000000000005224 181.0
HFD3_k127_3900999_11 Protein of unknown function (DUF664) - - - 0.0000000000000000000000000000000000009811 158.0
HFD3_k127_3900999_12 N-acetyltransferase - - - 0.000000000000000000000000000000000008845 151.0
HFD3_k127_3900999_13 - - - - 0.000000000000000000003636 107.0
HFD3_k127_3900999_14 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.0000000193 69.0
HFD3_k127_3900999_15 PFAM Peptidase M56, BlaR1 - - - 0.0000009522 63.0
HFD3_k127_3900999_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 477.0
HFD3_k127_3900999_3 Belongs to the thiolase family K00626,K07508 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 397.0
HFD3_k127_3900999_4 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 374.0
HFD3_k127_3900999_5 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 347.0
HFD3_k127_3900999_6 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000004568 271.0
HFD3_k127_3900999_7 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004542 272.0
HFD3_k127_3900999_8 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000001126 246.0
HFD3_k127_3900999_9 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000001193 241.0
HFD3_k127_3981138_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006366 411.0
HFD3_k127_3981138_1 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000000000000002203 243.0
HFD3_k127_3981138_2 Glycosyl transferase 4-like domain K08256,K12995 - 2.4.1.345,2.4.1.348 0.0000000000000000000000000000000000000000000000000000000000000005067 244.0
HFD3_k127_3981138_3 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000001809 206.0
HFD3_k127_3981138_4 Bacterial lipid A biosynthesis acyltransferase K02517,K22311 - 2.3.1.241,2.3.1.265 0.00000000000000000000000000001082 135.0
HFD3_k127_3981138_5 Transmembrane secretion effector - - - 0.00000000000000000005681 103.0
HFD3_k127_3981138_6 zinc-ribbon domain - - - 0.000004891 55.0
HFD3_k127_3981138_7 - - - - 0.00002238 53.0
HFD3_k127_3985573_0 COG2801 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 574.0
HFD3_k127_3985573_1 DinB family - - - 0.0000000000000000000000000000000000000000000003444 172.0
HFD3_k127_3985573_2 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000001589 166.0
HFD3_k127_3985573_3 PFAM response regulator receiver K02477,K07705 - - 0.0000000000000000000000000000000000357 156.0
HFD3_k127_3985573_4 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000000000000000000000000000000002758 146.0
HFD3_k127_3985573_5 Histidine kinase K08082 - 2.7.13.3 0.000000000000000000000000000006474 138.0
HFD3_k127_3985573_6 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation K09811 - - 0.00000000000000000000000003444 116.0
HFD3_k127_3985573_7 It is involved in the biological process described with proteolysis K01395,K08606 GO:0003008,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005576,GO:0005615,GO:0006508,GO:0006807,GO:0006928,GO:0007154,GO:0007267,GO:0007600,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016477,GO:0016485,GO:0016787,GO:0019233,GO:0019538,GO:0023052,GO:0030154,GO:0032501,GO:0032502,GO:0040011,GO:0043170,GO:0044238,GO:0044421,GO:0045165,GO:0045168,GO:0046331,GO:0048869,GO:0048870,GO:0050877,GO:0051179,GO:0051604,GO:0051674,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.24.18,3.4.24.63 0.0000000000002579 83.0
HFD3_k127_3985573_9 peptidylprolyl isomerase K03769 - 5.2.1.8 0.0000005343 63.0
HFD3_k127_4117021_0 PFAM peptidase M3A and M3B thimet oligopeptidase F K08602 - - 5.41e-208 676.0
HFD3_k127_4117021_1 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005548 462.0
HFD3_k127_4117021_10 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.000000000000000000000000000000000000000000000297 182.0
HFD3_k127_4117021_11 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000002111 188.0
HFD3_k127_4117021_12 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000004155 178.0
HFD3_k127_4117021_13 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.000000000000000000000000000000000001345 149.0
HFD3_k127_4117021_14 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000005782 131.0
HFD3_k127_4117021_15 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.00000000000000000000000000003037 137.0
HFD3_k127_4117021_16 DinB superfamily - - - 0.00000000000000000004659 98.0
HFD3_k127_4117021_17 Protein of unknown function (DUF3570) - - - 0.000000000000000005944 97.0
HFD3_k127_4117021_18 Thioredoxin-like - - - 0.000000000000000008985 92.0
HFD3_k127_4117021_19 Acylphosphatase K01512 - 3.6.1.7 0.000000000000001266 85.0
HFD3_k127_4117021_2 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006972 424.0
HFD3_k127_4117021_20 Forkhead associated domain - - - 0.00000000000003601 86.0
HFD3_k127_4117021_21 transferase activity, transferring glycosyl groups - - - 0.000000000001011 78.0
HFD3_k127_4117021_22 protein secretion K20276 - - 0.0000000001883 74.0
HFD3_k127_4117021_23 PFAM NHL repeat containing protein - - - 0.0000000003281 73.0
HFD3_k127_4117021_24 Conserved TM helix - - - 0.000000001329 67.0
HFD3_k127_4117021_25 Endonuclease Exonuclease Phosphatase K07004 - - 0.0000001974 65.0
HFD3_k127_4117021_26 Tetratricopeptide repeat - - - 0.000001088 60.0
HFD3_k127_4117021_28 - - - - 0.00005759 54.0
HFD3_k127_4117021_29 - - - - 0.00006543 49.0
HFD3_k127_4117021_3 Glycosyl transferases group 1 K13057 - 2.4.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 388.0
HFD3_k127_4117021_30 Cell Wall K01448 - 3.5.1.28 0.0001824 54.0
HFD3_k127_4117021_5 PFAM Glyoxalase bleomycin resistance protein dioxygenase K07104 - 1.13.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000001676 275.0
HFD3_k127_4117021_6 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000001387 225.0
HFD3_k127_4117021_7 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000001081 220.0
HFD3_k127_4117021_8 lyase activity - - - 0.0000000000000000000000000000000000000000000000000009958 206.0
HFD3_k127_4117021_9 cellulase activity K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000002479 205.0
HFD3_k127_4137441_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 7.07e-322 1007.0
HFD3_k127_4137441_1 Acyl-CoA dehydrogenase, middle domain - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 2.626e-213 683.0
HFD3_k127_4137441_2 peptidase activity, acting on L-amino acid peptides K07004,K09955 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006232 425.0
HFD3_k127_4137441_3 cellulose binding - - - 0.000000000000004286 90.0
HFD3_k127_4137441_4 transferase activity, transferring glycosyl groups - - - 0.00000000000001047 86.0
HFD3_k127_4137441_5 Belongs to the glycosyl hydrolase 13 family - - - 0.0000000001533 75.0
HFD3_k127_4137441_6 LVIVD repeat K01179 - 3.2.1.4 0.00000001776 68.0
HFD3_k127_4150467_0 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000009877 228.0
HFD3_k127_4150467_1 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000001309 216.0
HFD3_k127_4150467_3 - - - - 0.00000000003903 74.0
HFD3_k127_4150467_4 E-Z type HEAT repeats - - - 0.000000009172 68.0
HFD3_k127_4234602_0 Glycosyl hydrolase 36 superfamily, catalytic domain K00702,K13688 - 2.4.1.20 0.0 3251.0
HFD3_k127_4234602_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1362.0
HFD3_k127_4234602_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 410.0
HFD3_k127_4234602_11 ErfK YbiS YcfS YnhG family protein K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007012 398.0
HFD3_k127_4234602_12 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 394.0
HFD3_k127_4234602_13 Peptidase U62 modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 370.0
HFD3_k127_4234602_14 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007749 347.0
HFD3_k127_4234602_15 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007803 318.0
HFD3_k127_4234602_16 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 302.0
HFD3_k127_4234602_17 N-terminal domain of Peptidase_S41 in eukaryotic IRBP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002122 298.0
HFD3_k127_4234602_18 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006331 278.0
HFD3_k127_4234602_19 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000007792 276.0
HFD3_k127_4234602_2 Berberine and berberine like - - - 3.301e-278 863.0
HFD3_k127_4234602_20 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006095 261.0
HFD3_k127_4234602_21 COG2303 Choline dehydrogenase and related flavoproteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009469 268.0
HFD3_k127_4234602_22 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002906 252.0
HFD3_k127_4234602_23 Peptidase M15 - - - 0.000000000000000000000000000000000000000000000000000000000000004294 229.0
HFD3_k127_4234602_24 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000001681 228.0
HFD3_k127_4234602_25 OmpA family - - - 0.0000000000000000000000000000000000000000000000000000000000002533 222.0
HFD3_k127_4234602_26 Major pilin protein fimA - - - 0.0000000000000000000000000000000000000000000000000000003973 218.0
HFD3_k127_4234602_27 2Fe-2S -binding domain protein K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000001556 202.0
HFD3_k127_4234602_28 transposition K07483,K07497 GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000000002262 193.0
HFD3_k127_4234602_29 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000003791 206.0
HFD3_k127_4234602_3 Cytochrome C assembly protein - - - 4.27e-215 693.0
HFD3_k127_4234602_30 COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - 0.0000000000000000000000000000000000000000000000000001831 196.0
HFD3_k127_4234602_31 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000002382 214.0
HFD3_k127_4234602_32 efflux transmembrane transporter activity K15725 - - 0.0000000000000000000000000000000000000000000000002369 192.0
HFD3_k127_4234602_33 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000004458 145.0
HFD3_k127_4234602_35 Domain of unknown function (DUF4386) - - - 0.00000000000000000000000000000001383 136.0
HFD3_k127_4234602_36 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.00000000000000000000000000000001477 136.0
HFD3_k127_4234602_37 phosphoribosyltransferase K07100 - - 0.00000000000000000000000000000007962 143.0
HFD3_k127_4234602_38 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.000000000000000000000008311 109.0
HFD3_k127_4234602_39 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000001481 118.0
HFD3_k127_4234602_4 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005605 634.0
HFD3_k127_4234602_40 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000002949 111.0
HFD3_k127_4234602_41 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000004649 111.0
HFD3_k127_4234602_43 - - - - 0.0000000000000000001857 90.0
HFD3_k127_4234602_44 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000009177 96.0
HFD3_k127_4234602_45 glycosyl transferase, family 39 - - - 0.00000000000000001635 99.0
HFD3_k127_4234602_46 Rhomboid family K19225 - 3.4.21.105 0.0000000000000002308 94.0
HFD3_k127_4234602_47 Belongs to the universal stress protein A family - - - 0.0000000000000005936 91.0
HFD3_k127_4234602_48 DinB family - - - 0.000000000000005253 87.0
HFD3_k127_4234602_49 ribosomal large subunit export from nucleus - - - 0.000000000004853 74.0
HFD3_k127_4234602_5 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 604.0
HFD3_k127_4234602_50 Periplasmic or secreted lipoprotein - - - 0.00000000001886 76.0
HFD3_k127_4234602_51 PFAM transposase IS3 IS911 family protein K07497 - - 0.0000000003702 67.0
HFD3_k127_4234602_52 - - - - 0.0000002329 56.0
HFD3_k127_4234602_53 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10794 - 1.21.4.1 0.0000002538 57.0
HFD3_k127_4234602_54 Antibiotic biosynthesis monooxygenase - - - 0.00001411 55.0
HFD3_k127_4234602_55 Outer membrane protein beta-barrel domain - - - 0.00002464 57.0
HFD3_k127_4234602_56 Transposase K07483 - - 0.0003476 48.0
HFD3_k127_4234602_6 COG0076 Glutamate decarboxylase and related PLP-dependent K01593 - 4.1.1.105,4.1.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 593.0
HFD3_k127_4234602_7 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 526.0
HFD3_k127_4234602_8 Aminotransferase class-V K04127 - 5.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006189 454.0
HFD3_k127_4234602_9 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006068 442.0
HFD3_k127_4255582_0 Peptidase family M1 domain K01992 - - 0.0 1063.0
HFD3_k127_4255582_1 (ABC) transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 426.0
HFD3_k127_4255582_10 enzyme involved in biosynthesis of extracellular polysaccharides - - - 0.00000000000000000000000000004546 133.0
HFD3_k127_4255582_11 - - - - 0.000000000000000000000006384 109.0
HFD3_k127_4255582_12 membrane protein (DUF2079) - - - 0.00000000000000000000001056 117.0
HFD3_k127_4255582_14 - - - - 0.0000000000001155 80.0
HFD3_k127_4255582_15 Reeler domain - - - 0.0005518 50.0
HFD3_k127_4255582_2 chorismate binding enzyme K01657,K01665 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004908 367.0
HFD3_k127_4255582_3 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 335.0
HFD3_k127_4255582_4 Phenazine biosynthesis-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 299.0
HFD3_k127_4255582_5 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000001086 266.0
HFD3_k127_4255582_6 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000005081 238.0
HFD3_k127_4255582_7 alpha beta - - - 0.0000000000000000000000000000000000003545 158.0
HFD3_k127_4255582_8 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000001996 153.0
HFD3_k127_4255582_9 Amidohydrolase family - - - 0.0000000000000000000000000000001619 139.0
HFD3_k127_4256637_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 534.0
HFD3_k127_4256637_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 431.0
HFD3_k127_4256637_10 low molecular weight K01104,K20201 - 3.1.3.48,3.9.1.2 0.00000000000000000372 98.0
HFD3_k127_4256637_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006804 407.0
HFD3_k127_4256637_3 Associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 390.0
HFD3_k127_4256637_4 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 334.0
HFD3_k127_4256637_5 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003912 265.0
HFD3_k127_4256637_6 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000001227 173.0
HFD3_k127_4256637_7 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000005188 165.0
HFD3_k127_4256637_8 Belongs to the SUA5 family K07566 GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.87 0.00000000000000000000000000000000000003201 157.0
HFD3_k127_4256637_9 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000198 100.0
HFD3_k127_4284584_0 Berberine and berberine like - - - 4.713e-216 680.0
HFD3_k127_4284584_1 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005153 404.0
HFD3_k127_4284584_10 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000000000000003006 115.0
HFD3_k127_4284584_11 Diguanylate cyclase - - - 0.000000000000000000005115 107.0
HFD3_k127_4284584_12 long-chain fatty acid transport protein - - - 0.0000000000000103 90.0
HFD3_k127_4284584_13 Phage integrase family - - - 0.0000000000002642 81.0
HFD3_k127_4284584_14 Protein of unknown function (DUF998) - - - 0.000000000001515 76.0
HFD3_k127_4284584_15 exo-alpha-(2->6)-sialidase activity - - - 0.000002962 61.0
HFD3_k127_4284584_16 ATPase AAA-2 domain protein K03696 - - 0.0004054 48.0
HFD3_k127_4284584_2 regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 375.0
HFD3_k127_4284584_3 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006169 271.0
HFD3_k127_4284584_4 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006832 270.0
HFD3_k127_4284584_5 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000001849 190.0
HFD3_k127_4284584_6 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000000000000007517 197.0
HFD3_k127_4284584_7 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000001724 178.0
HFD3_k127_4284584_8 - - - - 0.0000000000000000000000000000000000003683 150.0
HFD3_k127_4284584_9 NHL repeat - - - 0.000000000000000000000000000000000002623 162.0
HFD3_k127_4338317_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 3.481e-207 691.0
HFD3_k127_4338317_1 M6 family metalloprotease domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 588.0
HFD3_k127_4338317_10 regulation of translation K03530 - - 0.0000000000000000000000000004073 116.0
HFD3_k127_4338317_11 - - - - 0.000000000000000000000000443 120.0
HFD3_k127_4338317_12 Domain of unknown function (DUF1929) - - - 0.000000000000000000000002146 119.0
HFD3_k127_4338317_13 Alkylmercury lyase - - - 0.000000000000000000003181 99.0
HFD3_k127_4338317_14 Protein of unknown function (DUF3052) - - - 0.000000000000003448 89.0
HFD3_k127_4338317_15 beta-galactosidase activity K01190 - 3.2.1.23 0.000000000001668 81.0
HFD3_k127_4338317_16 Parallel beta-helix repeats - - - 0.000000001973 72.0
HFD3_k127_4338317_17 Alkylmercury lyase - - - 0.0000003612 54.0
HFD3_k127_4338317_18 regulator of chromosome condensation, RCC1 - - - 0.00001436 58.0
HFD3_k127_4338317_19 - - - - 0.0002429 45.0
HFD3_k127_4338317_2 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 499.0
HFD3_k127_4338317_3 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 378.0
HFD3_k127_4338317_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 348.0
HFD3_k127_4338317_5 4Fe-4S dicluster domain K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 343.0
HFD3_k127_4338317_6 Winged helix DNA-binding domain K09927 - - 0.0000000000000000000000000000000000000000000000000000000000000000003532 248.0
HFD3_k127_4338317_7 endonuclease activity K07451 - - 0.0000000000000000000000000000000000000000000000000000001709 210.0
HFD3_k127_4338317_8 chromosome segregation K03497 - - 0.00000000000000000000000000000000002467 146.0
HFD3_k127_4338317_9 Beta-galactosidase - - - 0.000000000000000000000000000001362 138.0
HFD3_k127_4342489_0 transmembrane transporter activity - - - 7.224e-309 979.0
HFD3_k127_4342489_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 1.116e-287 936.0
HFD3_k127_4342489_10 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008134,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0022607,GO:0030170,GO:0032991,GO:0032993,GO:0036094,GO:0042127,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043388,GO:0043436,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046395,GO:0046983,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0051098,GO:0051099,GO:0051101,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051291,GO:0065003,GO:0065007,GO:0065009,GO:0070279,GO:0071704,GO:0071840,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1904796,GO:1904798,GO:2000677,GO:2000679 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000137 256.0
HFD3_k127_4342489_11 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003808 248.0
HFD3_k127_4342489_12 Pregnancy-associated plasma protein-A - - - 0.000000000000000000000000000000000000000000000000000000000000000000005993 249.0
HFD3_k127_4342489_13 Putative zinc-finger K03088 - - 0.00000000000000000000000000000000000000000000000000001036 201.0
HFD3_k127_4342489_14 membrane - - - 0.00000000000000000000000000000000000000002421 163.0
HFD3_k127_4342489_16 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000002646 120.0
HFD3_k127_4342489_17 Iron-binding zinc finger CDGSH type - - - 0.00000000000000000000001451 105.0
HFD3_k127_4342489_18 SURF1 family K14998 - - 0.00000000000000000000003578 111.0
HFD3_k127_4342489_19 Sulfurtransferase - - - 0.0000000000000000000001394 99.0
HFD3_k127_4342489_2 COG0488 ATPase components of ABC transporters with duplicated ATPase domains - - - 1.324e-253 794.0
HFD3_k127_4342489_20 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000004557 107.0
HFD3_k127_4342489_21 Putative phosphatase (DUF442) - - - 0.00000000000000001474 93.0
HFD3_k127_4342489_22 - - - - 0.000000000000687 76.0
HFD3_k127_4342489_23 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.0000000002982 72.0
HFD3_k127_4342489_24 - - - - 0.00000003605 63.0
HFD3_k127_4342489_3 Belongs to the MurCDEF family - - - 1.1e-239 758.0
HFD3_k127_4342489_4 PFAM peptidase M20 - - - 9.649e-196 619.0
HFD3_k127_4342489_5 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006243 568.0
HFD3_k127_4342489_6 Amidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005016 475.0
HFD3_k127_4342489_7 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007709 299.0
HFD3_k127_4342489_8 LytTr DNA-binding domain K02477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003224 283.0
HFD3_k127_4342489_9 cell redox homeostasis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001094 255.0
HFD3_k127_4403343_0 serine-type peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 500.0
HFD3_k127_4403343_1 PFAM sigma-54 factor interaction domain-containing protein K02481,K07714,K10943 - - 0.0000000000000000000000000000000000000000000000000000000000000001183 250.0
HFD3_k127_4403343_2 - - - - 0.000000000000000000000000000000000000000000000000000000002038 208.0
HFD3_k127_4403343_3 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000001002 151.0
HFD3_k127_4403343_4 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.000000000003915 73.0
HFD3_k127_4443338_0 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.0 1082.0
HFD3_k127_4443338_1 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.0 1051.0
HFD3_k127_4443338_10 DJ-1/PfpI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001027 252.0
HFD3_k127_4443338_11 water channel activity K02440,K06188,K09874 - - 0.000000000000000000000000000000000000000000000000000000000000000928 226.0
HFD3_k127_4443338_12 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000001833 241.0
HFD3_k127_4443338_13 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000007446 179.0
HFD3_k127_4443338_14 protocatechuate 3,4-dioxygenase activity K00449 - 1.13.11.3 0.000000000000002461 86.0
HFD3_k127_4443338_15 PFAM glycosyl transferase family 39 - - - 0.00000000000004155 85.0
HFD3_k127_4443338_16 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000005064 82.0
HFD3_k127_4443338_17 - - - - 0.000000000002068 68.0
HFD3_k127_4443338_18 Tfp pilus assembly protein FimV - - - 0.0000000006098 69.0
HFD3_k127_4443338_19 Fungalysin metallopeptidase (M36) - - - 0.00002211 56.0
HFD3_k127_4443338_2 Dehydrogenase E1 component K11381 - 1.2.4.4 5.549e-270 848.0
HFD3_k127_4443338_20 - - - - 0.00009202 51.0
HFD3_k127_4443338_3 Malate synthase K01638 - 2.3.3.9 6.714e-214 676.0
HFD3_k127_4443338_4 Phosphoenolpyruvate phosphomutase K01637 - 4.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 595.0
HFD3_k127_4443338_5 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006508 600.0
HFD3_k127_4443338_6 acyl-CoA dehydrogenase activity K00252 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.3.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007756 517.0
HFD3_k127_4443338_7 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 440.0
HFD3_k127_4443338_8 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006815 414.0
HFD3_k127_4443338_9 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 344.0
HFD3_k127_4448911_0 COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 396.0
HFD3_k127_4448911_1 MFS_1 like family - - - 0.0000000000000000000000000000000000000000000000000000000000002404 228.0
HFD3_k127_4448911_2 Methyltransferase domain - - - 0.00000000000000000000001096 119.0
HFD3_k127_4448911_3 - - - - 0.0000000000000001142 94.0
HFD3_k127_4449706_0 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 1.47e-212 689.0
HFD3_k127_4449706_1 SMART Integrin alpha beta-propellor repeat protein - - - 1.762e-203 685.0
HFD3_k127_4449706_10 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 454.0
HFD3_k127_4449706_11 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 405.0
HFD3_k127_4449706_12 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 369.0
HFD3_k127_4449706_13 FMN-dependent dehydrogenase K16422 - 1.1.3.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 368.0
HFD3_k127_4449706_14 Fibronectin type 3 domain K12685,K16785,K16786,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003295 387.0
HFD3_k127_4449706_15 PFAM Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 336.0
HFD3_k127_4449706_16 PFAM Silent information regulator protein Sir2 K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009669 317.0
HFD3_k127_4449706_17 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001741 286.0
HFD3_k127_4449706_18 RNA pseudouridylate synthase K06181 - 5.4.99.20 0.000000000000000000000000000000000000000000000000000000000000000000000000455 254.0
HFD3_k127_4449706_19 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000001802 246.0
HFD3_k127_4449706_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 619.0
HFD3_k127_4449706_20 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000013 225.0
HFD3_k127_4449706_21 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000005769 215.0
HFD3_k127_4449706_22 - - - - 0.0000000000000000000000000000000000017 160.0
HFD3_k127_4449706_23 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000002307 134.0
HFD3_k127_4449706_24 - - - - 0.00000000000000000000000000000007571 131.0
HFD3_k127_4449706_25 - K01278,K03561,K12287 - 3.4.14.5 0.000000000000000005571 99.0
HFD3_k127_4449706_26 LVIVD repeat K01179 - 3.2.1.4 0.00000000000000001253 99.0
HFD3_k127_4449706_27 hmm pf02371 - - - 0.00000000000004383 79.0
HFD3_k127_4449706_28 Putative metal-binding motif - - - 0.00000000000006422 87.0
HFD3_k127_4449706_29 Domain of unknown function (DUF4920) - - - 0.0000000000003805 79.0
HFD3_k127_4449706_3 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 621.0
HFD3_k127_4449706_30 YCII-related domain - - - 0.000000000001706 79.0
HFD3_k127_4449706_31 YCII-related domain - - - 0.00000000007173 74.0
HFD3_k127_4449706_32 cellulose binding - - - 0.00000000008475 74.0
HFD3_k127_4449706_33 Belongs to the peptidase S8 family - - - 0.0000000006852 71.0
HFD3_k127_4449706_34 cellulose binding K00505 - 1.14.18.1 0.000000004325 70.0
HFD3_k127_4449706_35 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000005721 70.0
HFD3_k127_4449706_36 domain protein K12287,K12549,K13735,K20276 - - 0.00000005313 65.0
HFD3_k127_4449706_37 Bacterial Ig-like domain (group 1) - - - 0.0000001915 63.0
HFD3_k127_4449706_38 Transposase zinc-binding domain - - - 0.0000682 52.0
HFD3_k127_4449706_4 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004042 614.0
HFD3_k127_4449706_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009151 568.0
HFD3_k127_4449706_6 L-lysine 6-monooxygenase (NADPH-requiring) K07222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 527.0
HFD3_k127_4449706_7 oligopeptide transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 527.0
HFD3_k127_4449706_8 COG2366 Protein related to penicillin acylase K01434 - 3.5.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 466.0
HFD3_k127_4449706_9 Major facilitator Superfamily K08162,K08226,K16211 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 451.0
HFD3_k127_4450411_0 TIGRFAM carbamoyl-phosphate synthase, large subunit K01955 - 6.3.5.5 0.0 1348.0
HFD3_k127_4450411_1 Carbamoyltransferase C-terminus K00612 - - 2.851e-246 774.0
HFD3_k127_4450411_10 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000007158 226.0
HFD3_k127_4450411_11 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.0000000000000000000000000000000000000000000000000000003014 216.0
HFD3_k127_4450411_12 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760,K15780 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8,6.3.4.19 0.000000000000000000000000000000000000000000000000001574 192.0
HFD3_k127_4450411_13 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000003129 180.0
HFD3_k127_4450411_14 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000003285 161.0
HFD3_k127_4450411_15 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.000000000000000000000000000000000015 147.0
HFD3_k127_4450411_16 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000005438 135.0
HFD3_k127_4450411_17 retrograde transport, endosome to Golgi K07095 - - 0.00000000000000000000000002043 114.0
HFD3_k127_4450411_18 - - - - 0.000000000000000000007393 108.0
HFD3_k127_4450411_19 oxidoreductase activity - - - 0.00000000000001246 89.0
HFD3_k127_4450411_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 1.651e-245 775.0
HFD3_k127_4450411_20 amine dehydrogenase activity - - - 0.00000000222 71.0
HFD3_k127_4450411_21 cellulose binding - - - 0.0000006071 62.0
HFD3_k127_4450411_22 PFAM Peptidase M56, BlaR1 - - - 0.000002342 61.0
HFD3_k127_4450411_23 Parallel beta-helix repeats - - - 0.00000304 61.0
HFD3_k127_4450411_24 peptidyl-tyrosine sulfation - - - 0.00006409 54.0
HFD3_k127_4450411_25 - - - - 0.00006777 50.0
HFD3_k127_4450411_26 carbamoyl transferase, NodU family K00612 - - 0.0001482 51.0
HFD3_k127_4450411_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 4.309e-245 788.0
HFD3_k127_4450411_4 TIGRFAM Carbamoyl-phosphate synthase, small subunit K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 475.0
HFD3_k127_4450411_5 Belongs to the enoyl-CoA hydratase isomerase family K01782,K01825 - 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 491.0
HFD3_k127_4450411_6 Thiolase, C-terminal domain K00626,K00632 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 421.0
HFD3_k127_4450411_7 Protein of unknown function (DUF418) K07148 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 359.0
HFD3_k127_4450411_8 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 301.0
HFD3_k127_4450411_9 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000000002302 262.0
HFD3_k127_4453489_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1121.0
HFD3_k127_4453489_1 Tricorn protease homolog - - - 0.0 1041.0
HFD3_k127_4453489_10 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00850,K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004214 493.0
HFD3_k127_4453489_11 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 389.0
HFD3_k127_4453489_12 PFAM Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 415.0
HFD3_k127_4453489_13 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 372.0
HFD3_k127_4453489_14 Protein of unknown function (DUF3798) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007882 349.0
HFD3_k127_4453489_15 Phospholipase D. Active site motifs. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 334.0
HFD3_k127_4453489_16 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 345.0
HFD3_k127_4453489_17 Cell wall formation K00075 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000001171 253.0
HFD3_k127_4453489_18 DNA alkylation repair - - - 0.00000000000000000000000000000000000000000000000000000000000000001103 250.0
HFD3_k127_4453489_19 Tetratricopeptide repeat K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000005415 245.0
HFD3_k127_4453489_2 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 3.62e-220 709.0
HFD3_k127_4453489_20 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000000000000000000000000001103 227.0
HFD3_k127_4453489_21 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000005217 196.0
HFD3_k127_4453489_22 COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - 0.000000000000000000000000000000000000000000001974 171.0
HFD3_k127_4453489_23 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000002481 177.0
HFD3_k127_4453489_24 HIT domain K02503 - - 0.00000000000000000000000000000000009584 138.0
HFD3_k127_4453489_25 cell redox homeostasis K02199,K03671 - - 0.00000000000000000000000001076 117.0
HFD3_k127_4453489_26 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000003108 118.0
HFD3_k127_4453489_27 oligosaccharyl transferase activity - - - 0.000000000000000000001746 110.0
HFD3_k127_4453489_29 protein conserved in bacteria K07401 - - 0.0000000002467 64.0
HFD3_k127_4453489_3 serine-type peptidase activity K01278 - 3.4.14.5 8.231e-220 714.0
HFD3_k127_4453489_30 selT selW selH selenoprotein K07401 - - 0.0000005619 53.0
HFD3_k127_4453489_31 Protein of unknown function (DUF1569) - - - 0.000001261 61.0
HFD3_k127_4453489_32 Cytochrome C biogenesis protein transmembrane region - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000004328 59.0
HFD3_k127_4453489_4 ABC transporter - - - 1.129e-198 633.0
HFD3_k127_4453489_5 Belongs to the citrate synthase family K01647 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009018 564.0
HFD3_k127_4453489_6 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005858 567.0
HFD3_k127_4453489_7 PFAM Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 539.0
HFD3_k127_4453489_8 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 532.0
HFD3_k127_4453489_9 transporter K12942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 491.0
HFD3_k127_4456528_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 488.0
HFD3_k127_4456528_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 432.0
HFD3_k127_4456528_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 351.0
HFD3_k127_4456528_3 Permeases of the drug metabolite transporter DMT superfamily - - - 0.0000000000000000000000000000000000001283 163.0
HFD3_k127_445996_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 588.0
HFD3_k127_445996_1 MreB/Mbl protein K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 467.0
HFD3_k127_445996_2 Penicillin-binding protein 2 K05515 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000922 421.0
HFD3_k127_445996_3 Rod shape-determining protein MreC K03570 - - 0.00000000000000004218 91.0
HFD3_k127_445996_4 rod shape-determining protein (MreD) K03571 - - 0.000000938 61.0
HFD3_k127_445996_5 - - - - 0.000602 53.0
HFD3_k127_4460038_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009392 428.0
HFD3_k127_4460038_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 432.0
HFD3_k127_4460038_2 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 391.0
HFD3_k127_4460038_3 Flotillin K07192 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008425 364.0
HFD3_k127_4460038_4 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007887 336.0
HFD3_k127_4460038_5 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005382 284.0
HFD3_k127_4460038_6 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000003981 257.0
HFD3_k127_4460038_7 dehydratase - - - 0.000000000000000000000000000000000000000000000000000000005898 222.0
HFD3_k127_4460038_8 to Int of Enterobacteriaceae UniRef RepID B3HI95_ECOLX - - - 0.00000000000000003072 93.0
HFD3_k127_4460038_9 Membrane protein implicated in regulation of membrane protease activity - - - 0.00000004685 62.0
HFD3_k127_4463638_0 MgsA AAA+ ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 473.0
HFD3_k127_4463638_1 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 316.0
HFD3_k127_4463638_10 Cobalt ABC transporter, permease protein CbiQ K02008 - - 0.0000004523 62.0
HFD3_k127_4463638_11 PFAM Methyltransferase domain - - - 0.000000551 61.0
HFD3_k127_4463638_12 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.0001714 55.0
HFD3_k127_4463638_2 ATPases associated with a variety of cellular activities K02006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 310.0
HFD3_k127_4463638_3 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006554 301.0
HFD3_k127_4463638_4 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.0000000000000000000000000000000000000000000000000006184 210.0
HFD3_k127_4463638_5 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000008244 191.0
HFD3_k127_4463638_6 Competence protein - - - 0.000000000000000000000000000000001376 145.0
HFD3_k127_4463638_7 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000009829 131.0
HFD3_k127_4463638_8 ThiS family K03636 - - 0.000000000000000000259 92.0
HFD3_k127_4463638_9 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.000000000000002085 89.0
HFD3_k127_4466757_0 Putative esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 406.0
HFD3_k127_4466757_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002956 245.0
HFD3_k127_4466757_2 bacterial-type flagellum-dependent cell motility K16147 - 2.4.99.16 0.0000000000000000000000000002429 129.0
HFD3_k127_4466757_3 Domain of unknown function (DUF4440) - - - 0.0000000000000000000000000003059 126.0
HFD3_k127_4466757_4 extracellular matrix structural constituent - - - 0.0001824 53.0
HFD3_k127_4620698_0 Amino acid permease - - - 1.237e-209 670.0
HFD3_k127_4620698_1 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 4.859e-203 645.0
HFD3_k127_4620698_10 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000001022 231.0
HFD3_k127_4620698_11 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000006347 215.0
HFD3_k127_4620698_12 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000001468 203.0
HFD3_k127_4620698_13 Uncharacterised protein family UPF0066 - - - 0.000000000000000000000000000000000000000001381 164.0
HFD3_k127_4620698_14 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000004904 164.0
HFD3_k127_4620698_15 - - - - 0.0000000000000000000000000000000000000006626 160.0
HFD3_k127_4620698_16 Acyl-ACP thioesterase K07107 - - 0.00000000000000000000000000000000000009315 163.0
HFD3_k127_4620698_17 Pregnancy-associated plasma protein-A - - - 0.000000000000000000000000000000002868 150.0
HFD3_k127_4620698_18 Glycosyl transferases group 1 K20922 - - 0.0000000000000000000000000000002679 144.0
HFD3_k127_4620698_19 - - - - 0.00000000000000000000002742 115.0
HFD3_k127_4620698_2 oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006642 518.0
HFD3_k127_4620698_20 Belongs to the peptidase S51 family - - - 0.000000000000000001245 102.0
HFD3_k127_4620698_21 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000001783 95.0
HFD3_k127_4620698_22 Trypsin-like serine protease K01337 - 3.4.21.50 0.000000000000001146 85.0
HFD3_k127_4620698_23 TIGRFAM phosphoserine phosphatase homoserine phosphotransferase bifunctional protein K02203 - 2.7.1.39,3.1.3.3 0.0000000000005406 72.0
HFD3_k127_4620698_24 phosphorelay signal transduction system - - - 0.0000000000109 77.0
HFD3_k127_4620698_25 copper resistance K07245,K14166 - - 0.00000000004501 77.0
HFD3_k127_4620698_26 Prolyl oligopeptidase family - - - 0.0000000001061 74.0
HFD3_k127_4620698_28 Protein of unknown function, DUF255 - - - 0.000000003927 68.0
HFD3_k127_4620698_3 Peptidase S8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 432.0
HFD3_k127_4620698_4 peptidase activity, acting on L-amino acid peptides K05996 - 3.4.17.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003293 361.0
HFD3_k127_4620698_5 UreE urease accessory protein, C-terminal domain K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002663 282.0
HFD3_k127_4620698_6 metalloendopeptidase activity K06013 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071586,GO:0071704,GO:0080120,GO:0140096,GO:1901564 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000003536 280.0
HFD3_k127_4620698_7 Short-chain dehydrogenase reductase SDR K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000001154 265.0
HFD3_k127_4620698_8 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000008499 254.0
HFD3_k127_4620698_9 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000205 235.0
HFD3_k127_4718104_0 Tricorn protease PDZ domain - - - 0.0 1124.0
HFD3_k127_4718104_1 NADH:flavin oxidoreductase / NADH oxidase family K09461 - 1.14.13.40 2.181e-320 1016.0
HFD3_k127_4718104_10 Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 344.0
HFD3_k127_4718104_11 Belongs to the thiolase family K00632 - 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 347.0
HFD3_k127_4718104_12 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006413 287.0
HFD3_k127_4718104_13 ABC transporter K02003,K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000051 278.0
HFD3_k127_4718104_14 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000005709 289.0
HFD3_k127_4718104_15 enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001258 280.0
HFD3_k127_4718104_16 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000004363 205.0
HFD3_k127_4718104_17 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000006985 215.0
HFD3_k127_4718104_18 Belongs to the peptidase S8 family K13276 - - 0.0000000000000000000000000000000000000000000000000000007532 223.0
HFD3_k127_4718104_19 LytTr DNA-binding domain K02477 - - 0.000000000000000000000000000000000000000000000000000005651 217.0
HFD3_k127_4718104_2 PFAM peptidase M13 K07386 - - 2.19e-248 786.0
HFD3_k127_4718104_20 Histidine kinase K08082 - 2.7.13.3 0.000000000000000000000000000000000000000000000000005437 194.0
HFD3_k127_4718104_21 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000004714 184.0
HFD3_k127_4718104_22 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000007461 153.0
HFD3_k127_4718104_23 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000147 136.0
HFD3_k127_4718104_24 Belongs to the peptidase S8 family - - - 0.000000000000000000000000002914 132.0
HFD3_k127_4718104_25 - - - - 0.0000000000000000000000879 111.0
HFD3_k127_4718104_26 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000001711 90.0
HFD3_k127_4718104_27 cellulose binding - - - 0.00000000000001292 90.0
HFD3_k127_4718104_28 - - - - 0.0000000000003145 83.0
HFD3_k127_4718104_29 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.000002079 55.0
HFD3_k127_4718104_3 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 606.0
HFD3_k127_4718104_4 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K01556 - 3.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007505 459.0
HFD3_k127_4718104_5 MatE K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008904 374.0
HFD3_k127_4718104_6 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 383.0
HFD3_k127_4718104_7 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004479 379.0
HFD3_k127_4718104_8 Tetratricopeptide repeat K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003709 370.0
HFD3_k127_4718104_9 tryptophan 2,3-dioxygenase activity K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 334.0
HFD3_k127_4743985_0 Peptidase family S41 - - - 3.694e-225 724.0
HFD3_k127_4743985_1 Aminotransferase class-III K15372 - 2.6.1.55 8.437e-213 669.0
HFD3_k127_4743985_10 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.00000000000000001838 93.0
HFD3_k127_4743985_11 - - - - 0.00000000000000001895 88.0
HFD3_k127_4743985_12 - - - - 0.00000000000003623 74.0
HFD3_k127_4743985_13 - - - - 0.00000000000005549 77.0
HFD3_k127_4743985_14 Peptidase_C39 like family - - - 0.0000000000003578 79.0
HFD3_k127_4743985_15 polysaccharide catabolic process K01179,K01218 - 3.2.1.4,3.2.1.78 0.000000000001169 78.0
HFD3_k127_4743985_17 cellulase activity - - - 0.0000000002271 70.0
HFD3_k127_4743985_19 bacterial OsmY and nodulation domain - - - 0.000000000401 72.0
HFD3_k127_4743985_2 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005902 481.0
HFD3_k127_4743985_20 YtxH-like protein - - - 0.000004995 55.0
HFD3_k127_4743985_21 - - - - 0.000005857 60.0
HFD3_k127_4743985_3 Domain of unknown function(DUF2779) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004259 434.0
HFD3_k127_4743985_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 428.0
HFD3_k127_4743985_5 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 316.0
HFD3_k127_4743985_6 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000003482 252.0
HFD3_k127_4743985_7 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000002009 226.0
HFD3_k127_4743985_8 AI-2E family transporter - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000000000000000000682 109.0
HFD3_k127_4743985_9 Tetratricopeptide repeat - - - 0.000000000000000000008923 99.0
HFD3_k127_4757273_0 Cytochrome C and Quinol oxidase polypeptide I - - - 1.071e-258 820.0
HFD3_k127_4757273_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 1.608e-256 799.0
HFD3_k127_4757273_10 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000495 598.0
HFD3_k127_4757273_11 Belongs to the HpcH HpaI aldolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007833 514.0
HFD3_k127_4757273_12 Carbon-nitrogen hydrolase K01431,K12251 - 3.5.1.53,3.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 497.0
HFD3_k127_4757273_13 5'-nucleotidase K01081,K01119,K11751 - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000625 527.0
HFD3_k127_4757273_14 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009083 496.0
HFD3_k127_4757273_15 allantoinase K01466 GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 480.0
HFD3_k127_4757273_16 Domain of unknown function (DUF4032) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 481.0
HFD3_k127_4757273_17 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K17722 - 1.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 453.0
HFD3_k127_4757273_18 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 435.0
HFD3_k127_4757273_19 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 424.0
HFD3_k127_4757273_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 9.271e-256 820.0
HFD3_k127_4757273_20 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 406.0
HFD3_k127_4757273_21 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 400.0
HFD3_k127_4757273_22 PFAM ABC transporter related K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 375.0
HFD3_k127_4757273_23 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 372.0
HFD3_k127_4757273_24 Peptidase M16 inactive domain K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 367.0
HFD3_k127_4757273_25 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006169 368.0
HFD3_k127_4757273_26 PFAM peptidase S1 and S6, chymotrypsin Hap K04771,K04772 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 347.0
HFD3_k127_4757273_27 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K15582 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 348.0
HFD3_k127_4757273_28 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 334.0
HFD3_k127_4757273_29 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 323.0
HFD3_k127_4757273_3 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 7.376e-240 748.0
HFD3_k127_4757273_30 translation initiation factor activity K06996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004879 316.0
HFD3_k127_4757273_31 Uncharacterized protein family (UPF0051) K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 322.0
HFD3_k127_4757273_32 transcription factor binding K02584,K11914 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007166 316.0
HFD3_k127_4757273_33 Binding-protein-dependent transport system inner membrane component K15581 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004402 316.0
HFD3_k127_4757273_34 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001815 285.0
HFD3_k127_4757273_35 Allantoate amidohydrolase K02083 - 3.5.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000003995 271.0
HFD3_k127_4757273_36 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K15580 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003709 271.0
HFD3_k127_4757273_37 Cytochrome C oxidase subunit II, periplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000272 245.0
HFD3_k127_4757273_38 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000002176 259.0
HFD3_k127_4757273_39 Cytochrome c oxidase subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000002371 241.0
HFD3_k127_4757273_4 Uncharacterized protein family (UPF0051) K09014 - - 1.421e-226 724.0
HFD3_k127_4757273_40 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000007711 244.0
HFD3_k127_4757273_41 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000001219 247.0
HFD3_k127_4757273_42 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000003156 229.0
HFD3_k127_4757273_43 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000001128 227.0
HFD3_k127_4757273_44 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000000000000000001214 215.0
HFD3_k127_4757273_45 Cupin 2, conserved barrel domain protein K14977 - 3.5.3.26 0.0000000000000000000000000000000000000000000000000000001917 207.0
HFD3_k127_4757273_46 xanthine dehydrogenase activity K13479 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000001525 212.0
HFD3_k127_4757273_47 Oxidoreductase activity. It is involved in the biological process described with metabolic process - GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0008670,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016627,GO:0016628,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 - 0.00000000000000000000000000000000000000000000000000002507 202.0
HFD3_k127_4757273_48 cellulase activity K06882 - - 0.00000000000000000000000000000000000000000000000000003109 201.0
HFD3_k127_4757273_49 4-amino-4-deoxy-L-arabinose transferase activity K13687 - - 0.0000000000000000000000000000000000000000000000000001944 208.0
HFD3_k127_4757273_5 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 3.212e-221 709.0
HFD3_k127_4757273_50 Calcineurin-like phosphoesterase K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.00000000000000000000000000000000000000000000000003475 191.0
HFD3_k127_4757273_51 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000007751 183.0
HFD3_k127_4757273_52 [2Fe-2S] binding domain K03518,K13483 - 1.2.5.3 0.00000000000000000000000000000000000000000000003442 185.0
HFD3_k127_4757273_53 LemA family K03744 - - 0.000000000000000000000000000000000000000000000663 173.0
HFD3_k127_4757273_54 OHCU decarboxylase K16840 - 4.1.1.97 0.000000000000000000000000000000000000000000001805 190.0
HFD3_k127_4757273_55 membrane - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000002048 181.0
HFD3_k127_4757273_56 peptidase - - - 0.00000000000000000000000000000000000000000004522 183.0
HFD3_k127_4757273_57 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000001379 171.0
HFD3_k127_4757273_58 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000004203 162.0
HFD3_k127_4757273_59 SUF system FeS assembly protein, NifU family K04488 - - 0.000000000000000000000000000000000000000002372 175.0
HFD3_k127_4757273_6 4Fe-4S dicluster domain K17723 - 1.3.1.1 5.07e-203 645.0
HFD3_k127_4757273_60 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000001363 156.0
HFD3_k127_4757273_61 Phosphodiester glycosidase - - - 0.000000000000000000000000000000000000001823 159.0
HFD3_k127_4757273_62 MerR, DNA binding K19591 - - 0.00000000000000000000000000000000000006728 148.0
HFD3_k127_4757273_63 Belongs to the peptidase S41A family K06399 - 3.4.21.116 0.0000000000000000000000000000000000002974 163.0
HFD3_k127_4757273_64 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000006729 157.0
HFD3_k127_4757273_65 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000007723 146.0
HFD3_k127_4757273_66 Squalene/phytoene synthase K00801 - 2.5.1.21 0.000000000000000000000000000000000004424 153.0
HFD3_k127_4757273_67 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000004622 158.0
HFD3_k127_4757273_68 Heme NO binding - - - 0.0000000000000000000000000000000004291 138.0
HFD3_k127_4757273_69 - K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.0000000000000000000000000000000004468 137.0
HFD3_k127_4757273_7 Permease for cytosine/purines, uracil, thiamine, allantoin K03457 - - 2.809e-202 651.0
HFD3_k127_4757273_70 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily K07127 - 3.5.2.17 0.00000000000000000000000000000002617 136.0
HFD3_k127_4757273_71 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.000000000000000000000000000002091 132.0
HFD3_k127_4757273_72 Iron-sulfur cluster assembly accessory protein K13628 - - 0.0000000000000000000000002331 115.0
HFD3_k127_4757273_73 hydrolases or acyltransferases alpha beta hydrolase superfamily - - - 0.000000000000000000002934 110.0
HFD3_k127_4757273_74 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000005482 100.0
HFD3_k127_4757273_75 - K20326 - - 0.00000000000000000002113 102.0
HFD3_k127_4757273_76 PFAM iron dependent repressor K03709 - - 0.0000000000000000007683 101.0
HFD3_k127_4757273_77 FlgD Ig-like domain - - - 0.00000000000000005034 96.0
HFD3_k127_4757273_78 Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway K03525 - 2.7.1.33 0.0000000000000000514 96.0
HFD3_k127_4757273_79 iron dependent repressor K03709 - - 0.000000000000001586 79.0
HFD3_k127_4757273_8 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 616.0
HFD3_k127_4757273_80 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000001831 83.0
HFD3_k127_4757273_81 Belongs to the Nudix hydrolase family - - - 0.00000000000009429 84.0
HFD3_k127_4757273_82 E3 Ubiquitin ligase - - - 0.000000000001679 80.0
HFD3_k127_4757273_85 Pfam:DUF59 - - - 0.00000000002806 73.0
HFD3_k127_4757273_86 Polymer-forming cytoskeletal - - - 0.000000001065 71.0
HFD3_k127_4757273_87 PFAM GGDEF domain containing protein - - - 0.000000002042 68.0
HFD3_k127_4757273_88 long-chain fatty acid transporting porin activity - - - 0.00000000375 68.0
HFD3_k127_4757273_89 OsmC-like protein - - - 0.000000006891 64.0
HFD3_k127_4757273_9 Amidohydrolase family K01464 - 3.5.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003904 605.0
HFD3_k127_4757273_90 - - - - 0.00000001007 68.0
HFD3_k127_4757273_91 helix_turn_helix, Arsenical Resistance Operon Repressor K21886 - - 0.000000188 61.0
HFD3_k127_4757273_92 - - - - 0.0000005951 61.0
HFD3_k127_4757273_93 Participates in initiation and elongation during chromosome replication - - - 0.0000006024 63.0
HFD3_k127_4757273_94 Septum formation initiator K05589 - - 0.000001256 61.0
HFD3_k127_4757273_95 AntiSigma factor - - - 0.000003198 58.0
HFD3_k127_4757273_96 Outer membrane protein, OMP85 family K07277 - - 0.000005525 59.0
HFD3_k127_4757273_97 isomerase activity - - - 0.0001283 55.0
HFD3_k127_4849797_0 Tricorn protease homolog K08676 - - 0.0 1351.0
HFD3_k127_4849797_1 Sortilin, neurotensin receptor 3, - - - 0.0 1207.0
HFD3_k127_4849797_2 PLD-like domain - - - 1.301e-258 806.0
HFD3_k127_4849797_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000092 593.0
HFD3_k127_4849797_4 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000001445 238.0
HFD3_k127_4849797_5 YwiC-like protein - - - 0.00000000000000000000000000000000000000006711 161.0
HFD3_k127_4849797_6 - - - - 0.0000000000000000000000000000252 122.0
HFD3_k127_4849797_7 MobA-like NTP transferase domain K07141,K19190 - 1.1.1.328,2.7.7.76 0.00000006269 65.0
HFD3_k127_4904213_0 Methionine synthase B12-binding module cap domain protein K00548,K15023 - 2.1.1.13,2.1.1.258 0.0 1269.0
HFD3_k127_4904213_1 Peptidase family M3 K01392 - 3.4.24.15 1.896e-217 697.0
HFD3_k127_4904213_10 Phosphoribulokinase / Uridine kinase family K00855,K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.19,2.7.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000001197 265.0
HFD3_k127_4904213_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001596 265.0
HFD3_k127_4904213_12 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001858 235.0
HFD3_k127_4904213_13 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000002058 233.0
HFD3_k127_4904213_14 Biotin/lipoate A/B protein ligase family K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000001145 200.0
HFD3_k127_4904213_15 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.0000000000000000000000000000000000000000000000000004467 193.0
HFD3_k127_4904213_16 galactose-6-phosphate isomerase activity K00761,K01808 - 2.4.2.9,5.3.1.6 0.0000000000000000000000000000000000000000004216 164.0
HFD3_k127_4904213_17 Thioesterase superfamily - - - 0.00000000000000000000000000000000002056 145.0
HFD3_k127_4904213_18 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000003131 113.0
HFD3_k127_4904213_19 oligosaccharyl transferase activity - - - 0.000000000000000000009619 108.0
HFD3_k127_4904213_2 Peptidase family M3 K01392 - 3.4.24.15 3.451e-203 657.0
HFD3_k127_4904213_20 Belongs to the HesB IscA family K13628 - - 0.0000000000000000009136 91.0
HFD3_k127_4904213_21 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000001245 95.0
HFD3_k127_4904213_22 endonuclease activity K07451 - - 0.0000000000000002814 84.0
HFD3_k127_4904213_23 - - - - 0.000000000000009475 87.0
HFD3_k127_4904213_24 Evidence 5 No homology to any previously reported sequences - - - 0.0000000003187 74.0
HFD3_k127_4904213_25 Phosphoglycerate mutase family K08296 - - 0.0000002808 60.0
HFD3_k127_4904213_26 Insulinase (Peptidase family M16) K07263 - - 0.000009692 58.0
HFD3_k127_4904213_27 zinc ion binding K11997,K12035 - 2.3.2.27 0.00001886 58.0
HFD3_k127_4904213_3 Quinolinate synthetase A protein K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 451.0
HFD3_k127_4904213_4 adenosine deaminase K01488 - 3.5.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009393 405.0
HFD3_k127_4904213_5 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005139 408.0
HFD3_k127_4904213_6 e3 binding domain K00658,K09699 GO:0003674,GO:0003824,GO:0004149,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008289,GO:0009060,GO:0009987,GO:0015980,GO:0016417,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016751,GO:0016999,GO:0017144,GO:0019752,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:0140096,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 2.3.1.168,2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 344.0
HFD3_k127_4904213_7 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 338.0
HFD3_k127_4904213_8 O-methyltransferase K00588 - 2.1.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 307.0
HFD3_k127_4904213_9 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 321.0
HFD3_k127_4909961_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 538.0
HFD3_k127_4909961_1 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 514.0
HFD3_k127_4909961_2 PFAM aldo keto reductase K05882 - 1.1.1.91 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 394.0
HFD3_k127_4909961_3 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 287.0
HFD3_k127_4909961_4 TRAP transporter T-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001631 280.0
HFD3_k127_4909961_5 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000257 249.0
HFD3_k127_4909961_6 - - - - 0.000000000000000000000000000000000000000001317 165.0
HFD3_k127_5004944_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.687e-201 650.0
HFD3_k127_5004944_1 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 501.0
HFD3_k127_5004944_10 Biotin carboxylase C-terminal domain K01968 - 6.4.1.4 0.00000000008867 75.0
HFD3_k127_5004944_11 Glycosyl hydrolase family 10 K01181 - 3.2.1.8 0.000002193 61.0
HFD3_k127_5004944_12 Domain of unknown function (DUF362) - - - 0.000002566 51.0
HFD3_k127_5004944_2 queuine tRNA-ribosyltransferase activity K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008726 354.0
HFD3_k127_5004944_3 Matrixin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 309.0
HFD3_k127_5004944_4 beta-N-acetylhexosaminidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000007192 260.0
HFD3_k127_5004944_5 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000007704 244.0
HFD3_k127_5004944_6 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000003149 160.0
HFD3_k127_5004944_7 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000004045 115.0
HFD3_k127_5004944_8 COG0346 Lactoylglutathione lyase and related lyases K05606 - 5.1.99.1 0.00000000000000000000000009062 124.0
HFD3_k127_5004944_9 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.0000000000000000001012 93.0
HFD3_k127_5115064_0 Outer membrane protein beta-barrel family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006906 626.0
HFD3_k127_5115064_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 419.0
HFD3_k127_5115064_2 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 410.0
HFD3_k127_5115064_3 ABC-type multidrug transport system ATPase component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000718 355.0
HFD3_k127_5115064_4 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 310.0
HFD3_k127_5115064_5 HlyD family secretion protein K01993 - - 0.00000000000000000000000000000000000000000004338 176.0
HFD3_k127_5115064_6 AhpC/TSA family - - - 0.000000000000000000000000000000000000143 155.0
HFD3_k127_5137834_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 1.027e-262 867.0
HFD3_k127_5137834_1 malonyl-CoA biosynthetic process K01962,K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 374.0
HFD3_k127_5137834_10 Peptidase, M23 family - - - 0.00000000000000000000000000003188 136.0
HFD3_k127_5137834_11 Zinc ion binding K11997,K12035 GO:0003008,GO:0003012,GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006936,GO:0006941,GO:0006996,GO:0007010,GO:0007610,GO:0007626,GO:0008150,GO:0008152,GO:0008270,GO:0008345,GO:0009653,GO:0009987,GO:0010927,GO:0016043,GO:0016567,GO:0016740,GO:0019538,GO:0019725,GO:0019787,GO:0022607,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030154,GO:0030239,GO:0030537,GO:0031032,GO:0031674,GO:0032446,GO:0032501,GO:0032502,GO:0032989,GO:0036211,GO:0042592,GO:0042692,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043292,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044444,GO:0044449,GO:0044464,GO:0046716,GO:0046872,GO:0046914,GO:0048468,GO:0048646,GO:0048747,GO:0048856,GO:0048869,GO:0051146,GO:0055001,GO:0055002,GO:0060249,GO:0061061,GO:0065007,GO:0065008,GO:0070647,GO:0070925,GO:0071704,GO:0071840,GO:0097435,GO:0099080,GO:0099081,GO:0099512,GO:0140096,GO:1901564 2.3.2.27 0.000000000000358 81.0
HFD3_k127_5137834_12 Belongs to the UPF0434 family K09791 - - 0.000000000009485 69.0
HFD3_k127_5137834_13 - - - - 0.00000000237 70.0
HFD3_k127_5137834_15 - - - - 0.000002985 61.0
HFD3_k127_5137834_16 cellulose binding - - - 0.000004039 61.0
HFD3_k127_5137834_17 Fibronectin type 3 domain - - - 0.00004508 57.0
HFD3_k127_5137834_2 Propeptide_C25 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 338.0
HFD3_k127_5137834_3 PKD domain K01179,K08651 - 3.2.1.4,3.4.21.66 0.000000000000000000000000000000000000000000000000000000000000008276 247.0
HFD3_k127_5137834_4 recombinase activity - - - 0.0000000000000000000000000000000000000000000000000000000003217 221.0
HFD3_k127_5137834_5 Protein of unknown function (DUF971) - - - 0.000000000000000000000000000000000000000000000000000000001136 229.0
HFD3_k127_5137834_6 Evidence 5 No homology to any previously reported sequences K17713 - - 0.00000000000000000000000000000000000000000000000001085 208.0
HFD3_k127_5137834_7 SMART AAA ATPase K02450 - - 0.00000000000000000000000000000000000000000000000001408 209.0
HFD3_k127_5137834_8 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000007325 149.0
HFD3_k127_5137834_9 Two component regulator propeller - - - 0.000000000000000000000000000001112 133.0
HFD3_k127_517755_0 L-asparaginase II - - - 0.000000000000000000000000000000000000000000000000000000000000000004887 241.0
HFD3_k127_517755_1 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.0000000000000000000000000000000000000000000000000000000000000003294 243.0
HFD3_k127_517755_2 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000002214 212.0
HFD3_k127_517755_3 PFAM Peptidase M16 inactive domain K07263 - - 0.0000000000000000000000000005759 132.0
HFD3_k127_517755_4 - - - - 0.00000000000002125 85.0
HFD3_k127_517755_5 COG3209 Rhs family protein - - - 0.00000001463 68.0
HFD3_k127_517755_6 COG3209 Rhs family protein - - - 0.0003554 54.0
HFD3_k127_5178028_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 377.0
HFD3_k127_5178028_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 353.0
HFD3_k127_5178028_10 - - - - 0.0001618 50.0
HFD3_k127_5178028_2 Psort location Cytoplasmic, score 8.87 K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006295 313.0
HFD3_k127_5178028_3 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000161 215.0
HFD3_k127_5178028_4 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000009707 145.0
HFD3_k127_5178028_5 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000002467 149.0
HFD3_k127_5178028_6 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000001317 141.0
HFD3_k127_5178028_7 Peptidylprolyl isomerase K03770 - 5.2.1.8 0.00000000000000000000237 111.0
HFD3_k127_5178028_8 helix_turn_helix, mercury resistance - - - 0.000000000000000004738 97.0
HFD3_k127_5178028_9 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000002148 62.0
HFD3_k127_5190475_0 ABC transporter transmembrane region K11085 - - 1.5e-235 743.0
HFD3_k127_5190475_1 major pilin protein fima - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 341.0
HFD3_k127_5190475_2 endonuclease activity K07451 - - 0.00000000005887 65.0
HFD3_k127_5190475_3 - - - - 0.0003264 54.0
HFD3_k127_5265556_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138,K18307 - - 0.0 1217.0
HFD3_k127_5265556_1 Dehydrogenase E1 component K00164 - 1.2.4.2 6.116e-257 853.0
HFD3_k127_5265556_10 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000045 279.0
HFD3_k127_5265556_11 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000007612 262.0
HFD3_k127_5265556_12 iron-sulfur cluster assembly K07400,K13628 - - 0.00000000000000000000000000000000000000000000000000000000000000000002054 243.0
HFD3_k127_5265556_13 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001197 227.0
HFD3_k127_5265556_14 PFAM response regulator receiver K02483,K07658,K07668 - - 0.0000000000000000000000000000008491 128.0
HFD3_k127_5265556_15 Tellurite resistance protein TehB - - - 0.00000000000000000001204 105.0
HFD3_k127_5265556_16 Methyltransferase domain - - - 0.000000000000000006095 93.0
HFD3_k127_5265556_17 Extracellular solute-binding protein, family 5 K02035 - - 0.0000000003712 69.0
HFD3_k127_5265556_18 Domain of unknown function (DUF4114) - - - 0.000002991 58.0
HFD3_k127_5265556_19 Tetratricopeptide repeat - - - 0.00003055 57.0
HFD3_k127_5265556_2 UvrD/REP helicase N-terminal domain K03657,K07465 - 3.6.4.12 4.016e-216 709.0
HFD3_k127_5265556_20 peptidyl-tyrosine sulfation - - - 0.00005121 56.0
HFD3_k127_5265556_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 491.0
HFD3_k127_5265556_4 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0000166,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009507,GO:0009536,GO:0010035,GO:0010038,GO:0016020,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017076,GO:0019866,GO:0030554,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0046686,GO:0046872,GO:0046914,GO:0048046,GO:0050896,GO:0050897,GO:0055114,GO:0070469,GO:0097159,GO:0097367,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 469.0
HFD3_k127_5265556_5 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 422.0
HFD3_k127_5265556_6 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 376.0
HFD3_k127_5265556_7 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 355.0
HFD3_k127_5265556_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 323.0
HFD3_k127_5265556_9 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 313.0
HFD3_k127_5289363_0 Amidohydrolase family - - - 5.254e-262 878.0
HFD3_k127_5289363_1 PFAM Peptidase S10, serine carboxypeptidase - - - 4.481e-196 639.0
HFD3_k127_5289363_2 Transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 366.0
HFD3_k127_5289363_3 UDP-glucoronosyl and UDP-glucosyl transferase - - - 0.00000000000000000000000000000000000000000000000004847 205.0
HFD3_k127_5289363_4 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000006739 190.0
HFD3_k127_5289363_5 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000001128 152.0
HFD3_k127_5289363_7 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.00008656 56.0
HFD3_k127_5289363_8 PKD domain K01179,K08651 - 3.2.1.4,3.4.21.66 0.0001143 55.0
HFD3_k127_5289363_9 Kelch motif K20285 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0002471 53.0
HFD3_k127_5314500_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 2.988e-301 949.0
HFD3_k127_5314500_1 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 416.0
HFD3_k127_5314500_2 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009414 333.0
HFD3_k127_5314500_3 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009745 332.0
HFD3_k127_5314500_4 Domain of unknown function (DUF4139) - - - 0.0000000000000000000000000000000000000000000000000000000008956 220.0
HFD3_k127_5314500_5 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000004419 216.0
HFD3_k127_5314500_6 enzyme binding K00567,K07443 - 2.1.1.63 0.0000000000000000000000000005564 120.0
HFD3_k127_5314500_7 Polysaccharide deacetylase - - - 0.00000000000000000000000125 121.0
HFD3_k127_5314500_8 Membrane - - - 0.000000000000006397 88.0
HFD3_k127_534374_0 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 308.0
HFD3_k127_534374_1 Phage integrase family - - - 0.000000000000000000000000000000000000000000000006866 192.0
HFD3_k127_534374_2 Histidine kinase K01768,K12132 - 2.7.11.1,4.6.1.1 0.000000000000000000000000000601 117.0
HFD3_k127_534374_3 Histidine kinase - - - 0.000000000000000000008477 108.0
HFD3_k127_534374_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000201 85.0
HFD3_k127_534374_5 - - - - 0.00002656 46.0
HFD3_k127_5343915_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 7.065e-241 759.0
HFD3_k127_5343915_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.359e-235 736.0
HFD3_k127_5343915_10 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 395.0
HFD3_k127_5343915_11 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000003365 246.0
HFD3_k127_5343915_12 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000001088 237.0
HFD3_k127_5343915_13 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000001065 195.0
HFD3_k127_5343915_14 Protein of unknown function (DUF520) K09767 - - 0.00000000000000000000000000000000000000000000000007963 183.0
HFD3_k127_5343915_15 methyltransferase - - - 0.0000000000000000000000000000000000000000114 165.0
HFD3_k127_5343915_16 Domain of unknown function (DUF1731) K07071 - - 0.0000000000000000000000000000000000000001872 165.0
HFD3_k127_5343915_17 4-amino-4-deoxy-L-arabinose transferase activity K07264 - 2.4.2.43 0.0000000000000000000000000000000000006169 162.0
HFD3_k127_5343915_18 TPM domain K06872 - - 0.00000000000000000000000000000001125 139.0
HFD3_k127_5343915_19 PFAM response regulator receiver K02483,K07658,K07668 - - 0.00000000000000000000000001873 128.0
HFD3_k127_5343915_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 8.803e-225 706.0
HFD3_k127_5343915_20 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000002385 115.0
HFD3_k127_5343915_21 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000007973 111.0
HFD3_k127_5343915_22 NUDIX domain K08310 - 3.6.1.67 0.0000000000000000000009068 103.0
HFD3_k127_5343915_23 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000001186 104.0
HFD3_k127_5343915_24 ACT domain K09707 - - 0.00000000000000000008561 105.0
HFD3_k127_5343915_25 nucleotidyltransferase activity - - - 0.0000000000000000003856 99.0
HFD3_k127_5343915_26 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000008317 85.0
HFD3_k127_5343915_27 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000002735 78.0
HFD3_k127_5343915_28 4Fe-4S single cluster domain K05337 - - 0.00000002256 58.0
HFD3_k127_5343915_29 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.0000006536 54.0
HFD3_k127_5343915_3 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 9.774e-196 622.0
HFD3_k127_5343915_30 pectinesterase activity K10117 - - 0.0000008931 62.0
HFD3_k127_5343915_31 response regulator K03413 - - 0.000002981 61.0
HFD3_k127_5343915_32 Hemerythrin HHE cation binding domain - - - 0.00004774 55.0
HFD3_k127_5343915_33 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.0003772 49.0
HFD3_k127_5343915_4 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005624 526.0
HFD3_k127_5343915_5 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 491.0
HFD3_k127_5343915_6 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 464.0
HFD3_k127_5343915_7 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 437.0
HFD3_k127_5343915_8 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 409.0
HFD3_k127_5343915_9 PFAM sigma-54 factor interaction domain-containing protein K21405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008557 418.0
HFD3_k127_5377912_1 TonB-dependent receptor - - - 4.98e-258 822.0
HFD3_k127_5377912_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 446.0
HFD3_k127_5377912_3 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 379.0
HFD3_k127_5377912_4 Carbohydrate ABC transporter ATP-binding protein, CUT1 family K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 376.0
HFD3_k127_5377912_5 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000003375 258.0
HFD3_k127_5377912_6 phospholipase Carboxylesterase - - - 0.00000000000000000000000000000000000000000000000005121 200.0
HFD3_k127_5377912_7 TIGRFAM Tyrosine recombinase XerD K04763 - - 0.00000000000000000000000000000000002696 156.0
HFD3_k127_5413501_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1278.0
HFD3_k127_5413501_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1272.0
HFD3_k127_5413501_10 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 364.0
HFD3_k127_5413501_11 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 362.0
HFD3_k127_5413501_12 imidazolonepropionase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004676 370.0
HFD3_k127_5413501_13 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 373.0
HFD3_k127_5413501_14 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007369 362.0
HFD3_k127_5413501_15 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 350.0
HFD3_k127_5413501_16 PFAM amino acid permease-associated region K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000951 291.0
HFD3_k127_5413501_17 Protein of unknown function (DUF1211) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001448 261.0
HFD3_k127_5413501_18 Alpha/beta hydrolase family K01563 - 3.8.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000006032 273.0
HFD3_k127_5413501_19 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002928 253.0
HFD3_k127_5413501_2 succinate dehydrogenase K00239 GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363 1.3.5.1,1.3.5.4 4.279e-249 794.0
HFD3_k127_5413501_20 Conserved hypothetical protein 698 - - - 0.0000000000000000000000000000000000000000000000000000000000001743 227.0
HFD3_k127_5413501_21 cellulase activity - - - 0.000000000000000000000000000000000000000000000000000000000009175 235.0
HFD3_k127_5413501_22 - - - - 0.000000000000000000000000000000000000000000000000000000000161 209.0
HFD3_k127_5413501_23 CDGSH-type zinc finger. Function unknown. - - - 0.0000000000000000000000000000000000000000000000000000000012 208.0
HFD3_k127_5413501_24 AIR synthase related protein, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000002542 197.0
HFD3_k127_5413501_25 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.0000000000000000000000000000000000000000000000000002003 209.0
HFD3_k127_5413501_26 PFAM Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.0000000000000000000000000000000000000000000000000002903 211.0
HFD3_k127_5413501_27 - - - - 0.000000000000000000000000000000000000000000002493 171.0
HFD3_k127_5413501_28 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000008692 184.0
HFD3_k127_5413501_29 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000005801 176.0
HFD3_k127_5413501_3 Amidohydrolase family K01443 - 3.5.1.25 1.698e-235 765.0
HFD3_k127_5413501_30 Thrombospondin type 3 repeat - - - 0.00000000000000000000000000000000000001973 154.0
HFD3_k127_5413501_31 TIGRFAM N-terminal double-transmembrane domain - - - 0.00000000000000000000000000000000000002517 164.0
HFD3_k127_5413501_32 peroxiredoxin activity - - - 0.00000000000000000000000000000000000006691 150.0
HFD3_k127_5413501_33 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0000000000000000000000000000000000002568 144.0
HFD3_k127_5413501_34 Outer membrane efflux protein - - - 0.000000000000000000000000000000000003394 154.0
HFD3_k127_5413501_35 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000000000000004699 142.0
HFD3_k127_5413501_36 Methyltransferase type 12 - - - 0.00000000000000000000000000000002388 136.0
HFD3_k127_5413501_39 Methyltransferase domain - - - 0.000000000000000000006931 102.0
HFD3_k127_5413501_4 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01535,K01537 - 3.6.3.6,3.6.3.8 1.99e-222 722.0
HFD3_k127_5413501_40 response regulator - - - 0.00000000000000000001144 102.0
HFD3_k127_5413501_41 FlgD Ig-like domain - - - 0.0000000000000000009431 101.0
HFD3_k127_5413501_42 WD40-like Beta Propeller Repeat - - - 0.00000000000000009293 92.0
HFD3_k127_5413501_43 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02275,K17686 - 1.9.3.1,3.6.3.54 0.000000000005092 72.0
HFD3_k127_5413501_44 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000006016 78.0
HFD3_k127_5413501_45 - - - - 0.00000000001028 69.0
HFD3_k127_5413501_46 PFAM UspA domain protein K06149 - - 0.00000000002747 72.0
HFD3_k127_5413501_47 Membrane - - - 0.000000006874 70.0
HFD3_k127_5413501_48 Belongs to the glycosyl hydrolase 13 family - - - 0.00000001074 68.0
HFD3_k127_5413501_49 Belongs to the glycosyl hydrolase 13 family - - - 0.00000002145 67.0
HFD3_k127_5413501_5 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 564.0
HFD3_k127_5413501_50 peptidyl-tyrosine sulfation - - - 0.0000009665 62.0
HFD3_k127_5413501_51 S4 RNA-binding domain - - - 0.00001077 50.0
HFD3_k127_5413501_52 cellulase activity K01081,K01179,K06931 - 3.1.3.5,3.2.1.4 0.00002734 58.0
HFD3_k127_5413501_54 Fibronectin type 3 domain K01179,K01361,K01637,K01729,K09942,K20276 - 3.2.1.4,3.4.21.96,4.1.3.1,4.2.2.3 0.00005188 57.0
HFD3_k127_5413501_55 Pfam Proprotein convertase - - - 0.0002775 54.0
HFD3_k127_5413501_6 Fungalysin/Thermolysin Propeptide Motif K20274 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005843 503.0
HFD3_k127_5413501_7 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000949 443.0
HFD3_k127_5413501_8 PFAM Bacterial protein of K07093 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 430.0
HFD3_k127_5413501_9 Sodium/calcium exchanger protein K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009291 390.0
HFD3_k127_5556336_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 500.0
HFD3_k127_5556336_1 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 411.0
HFD3_k127_5556336_10 Polysaccharide biosynthesis protein K15856 - 1.1.1.281 0.0000000000000000000000000000000000000000000000000000000000000000000001824 252.0
HFD3_k127_5556336_11 glycosyl transferase family 8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002183 264.0
HFD3_k127_5556336_12 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000001567 236.0
HFD3_k127_5556336_13 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000643 223.0
HFD3_k127_5556336_14 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.0000000000000000000000000000000000000000000000000004581 201.0
HFD3_k127_5556336_15 Protein conserved in bacteria K06320,K20444 - - 0.000000000000000000000000000000000000000000000000305 199.0
HFD3_k127_5556336_16 Glycosyl transferase, family 2 K16555 - - 0.00000000000000000000000000000000000000000000007629 179.0
HFD3_k127_5556336_17 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000001173 156.0
HFD3_k127_5556336_18 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - - 0.0000000000000000000000000000000898 138.0
HFD3_k127_5556336_19 glycosyl transferase family 2 - - - 0.0000000000000000000000000001854 132.0
HFD3_k127_5556336_2 Polysaccharide biosynthesis protein K15856 - 1.1.1.281 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 408.0
HFD3_k127_5556336_20 Glycosyl transferase, family 2 K00786 - - 0.0000000000000000000000000002109 128.0
HFD3_k127_5556336_21 WxcM-like, C-terminal K01790 - 5.1.3.13 0.0000000000000000000005496 103.0
HFD3_k127_5556336_23 transferase activity, transferring glycosyl groups - - - 0.000000000002662 68.0
HFD3_k127_5556336_24 Cupin domain - - - 0.0000000008031 70.0
HFD3_k127_5556336_25 ubiE/COQ5 methyltransferase family - - - 0.000007595 60.0
HFD3_k127_5556336_3 ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 397.0
HFD3_k127_5556336_4 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006088 394.0
HFD3_k127_5556336_5 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710,K12450 GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 4.2.1.46,4.2.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 388.0
HFD3_k127_5556336_6 undecaprenyl-phosphate glucose phosphotransferase activity K03606,K20997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 367.0
HFD3_k127_5556336_7 ATPases associated with a variety of cellular activities K01990,K09689,K09691 - 3.6.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 348.0
HFD3_k127_5556336_8 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009093 347.0
HFD3_k127_5556336_9 Glycosyl transferase, family 2 K20444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009536 286.0
HFD3_k127_5633551_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1064.0
HFD3_k127_5633551_1 4Fe-4S dicluster domain K00184 - - 6.791e-232 754.0
HFD3_k127_5633551_11 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 482.0
HFD3_k127_5633551_12 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 488.0
HFD3_k127_5633551_13 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 468.0
HFD3_k127_5633551_14 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 486.0
HFD3_k127_5633551_15 Part of a membrane complex involved in electron transport K03615 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 406.0
HFD3_k127_5633551_16 dihydroorotate dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 423.0
HFD3_k127_5633551_17 TIGRFAM 6-phosphogluconate dehydrogenase, decarboxylating K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008699 389.0
HFD3_k127_5633551_18 Major facilitator Superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 393.0
HFD3_k127_5633551_19 Pyridoxal-phosphate dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 372.0
HFD3_k127_5633551_2 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667 - 4.1.99.1 8.192e-204 660.0
HFD3_k127_5633551_20 Threonine dehydratase K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 377.0
HFD3_k127_5633551_21 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000731 388.0
HFD3_k127_5633551_22 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00615,K00616,K13810 - 2.2.1.1,2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 364.0
HFD3_k127_5633551_23 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009327 359.0
HFD3_k127_5633551_24 Fe-S cluster K03616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 346.0
HFD3_k127_5633551_25 COGs COG0674 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductase alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003678 364.0
HFD3_k127_5633551_26 Belongs to the ATCase OTCase family - GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0019627,GO:0034641,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 324.0
HFD3_k127_5633551_27 OST-HTH/LOTUS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 306.0
HFD3_k127_5633551_28 Pyridoxal-phosphate dependent enzyme K12339,K21148 - 2.5.1.113,2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009554 313.0
HFD3_k127_5633551_29 Belongs to the carbamate kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000227 287.0
HFD3_k127_5633551_3 Belongs to the cysteine synthase cystathionine beta- synthase family - - - 1.105e-198 633.0
HFD3_k127_5633551_30 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005376 287.0
HFD3_k127_5633551_31 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00347,K03614 - 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004332 292.0
HFD3_k127_5633551_32 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000001843 282.0
HFD3_k127_5633551_33 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000207 273.0
HFD3_k127_5633551_34 N-acetylglucosaminylinositol deacetylase activity K22135 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007899 284.0
HFD3_k127_5633551_35 Part of a membrane complex involved in electron transport K03617 - - 0.000000000000000000000000000000000000000000000000000000000000000000003472 249.0
HFD3_k127_5633551_36 PFAM glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000002909 234.0
HFD3_k127_5633551_37 Part of a membrane complex involved in electron transport K03613 - - 0.0000000000000000000000000000000000000000000000000000000000000002219 240.0
HFD3_k127_5633551_38 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000006456 236.0
HFD3_k127_5633551_39 Major Facilitator Superfamily K08223 - - 0.00000000000000000000000000000000000000000000000000000261 206.0
HFD3_k127_5633551_4 PFAM UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004521 586.0
HFD3_k127_5633551_40 Pfam Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000006479 202.0
HFD3_k127_5633551_41 Part of a membrane complex involved in electron transport K03612 - - 0.00000000000000000000000000000000000000000001833 183.0
HFD3_k127_5633551_42 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000002032 162.0
HFD3_k127_5633551_43 s1 p1 nuclease - - - 0.000000000000000000000000000000000000001363 164.0
HFD3_k127_5633551_44 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000005957 154.0
HFD3_k127_5633551_45 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.0000000000000000000000000000000000009182 151.0
HFD3_k127_5633551_46 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00169 GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0050896,GO:0055114 1.2.7.1 0.000000000000000000000000000000004702 148.0
HFD3_k127_5633551_47 proteolysis - - - 0.00000000000000000000000000000008196 136.0
HFD3_k127_5633551_48 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.00000000000000000000000000001073 138.0
HFD3_k127_5633551_49 - - - - 0.0000000000000000000000004931 109.0
HFD3_k127_5633551_5 MatE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008511 569.0
HFD3_k127_5633551_50 oligosaccharyl transferase activity - - - 0.0000000000000000000000005013 122.0
HFD3_k127_5633551_51 PFAM OsmC family protein K07397 - - 0.00000000000000000000002522 116.0
HFD3_k127_5633551_52 cytochrome c - - - 0.00000000000000000000007288 105.0
HFD3_k127_5633551_53 Bacterial membrane protein YfhO - - - 0.0000000000000000000001422 115.0
HFD3_k127_5633551_54 of the drug metabolite transporter (DMT) superfamily - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000000000000001567 100.0
HFD3_k127_5633551_55 lactoylglutathione lyase activity - - - 0.0000000000002045 85.0
HFD3_k127_5633551_56 Protein of unknown function (DUF3341) - - - 0.0000000000004012 83.0
HFD3_k127_5633551_57 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000002409 70.0
HFD3_k127_5633551_58 Phage integrase family - - - 0.0000000006385 63.0
HFD3_k127_5633551_59 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000003065 65.0
HFD3_k127_5633551_6 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 568.0
HFD3_k127_5633551_60 - - - - 0.00000004626 58.0
HFD3_k127_5633551_61 Galactose oxidase, central domain - - - 0.0000002883 63.0
HFD3_k127_5633551_62 PFAM Forkhead-associated protein - - - 0.0001844 51.0
HFD3_k127_5633551_65 electron transfer activity K05337 - - 0.0004335 46.0
HFD3_k127_5633551_66 - - - - 0.0008714 46.0
HFD3_k127_5633551_7 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00322 - 1.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 533.0
HFD3_k127_5633551_8 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005986 527.0
HFD3_k127_5633551_9 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 522.0
HFD3_k127_5751765_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 547.0
HFD3_k127_5751765_1 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 443.0
HFD3_k127_5751765_2 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000964 241.0
HFD3_k127_5751765_3 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000003575 188.0
HFD3_k127_5751765_4 Protein of unknown function DUF47 K02039,K07220 - - 0.00000000000000000000000000000000000000000000000324 183.0
HFD3_k127_5807225_0 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 430.0
HFD3_k127_5807225_1 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 361.0
HFD3_k127_5807225_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 356.0
HFD3_k127_5807225_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 298.0
HFD3_k127_5807225_4 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001135 244.0
HFD3_k127_5807225_5 DHH family K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000001059 220.0
HFD3_k127_5807225_6 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.00000000000000000000000000000000000000000000003939 189.0
HFD3_k127_5807225_7 ABC transporter K02193 - 3.6.3.41 0.000000000000000000000000000000002557 139.0
HFD3_k127_5868374_0 MutL protein K00854 - 2.7.1.17 2.446e-239 759.0
HFD3_k127_5868374_1 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 583.0
HFD3_k127_5868374_10 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 362.0
HFD3_k127_5868374_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008635 361.0
HFD3_k127_5868374_12 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573,K12585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005452 347.0
HFD3_k127_5868374_13 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003625 332.0
HFD3_k127_5868374_14 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006065 327.0
HFD3_k127_5868374_15 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005366 340.0
HFD3_k127_5868374_16 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008049 265.0
HFD3_k127_5868374_17 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000000000000000000000000000000005507 234.0
HFD3_k127_5868374_18 - - - - 0.00000000000000000000000000000000000000000000000000002843 194.0
HFD3_k127_5868374_19 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000005865 164.0
HFD3_k127_5868374_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 584.0
HFD3_k127_5868374_20 COGs COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein K04027,K04028 GO:0003674,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0031469,GO:0031471,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464 - 0.000000000000000000000000000002878 131.0
HFD3_k127_5868374_21 Carbon dioxide concentrating mechanism carboxysome shell protein - - - 0.0000000000000000000000000000073 138.0
HFD3_k127_5868374_22 PFAM biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.00000000000000000000000001647 120.0
HFD3_k127_5868374_23 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530,K05788 - - 0.00000000000000000000005309 104.0
HFD3_k127_5868374_24 Ethanolamine utilization protein EutN K04028 - - 0.000000000000000000003435 101.0
HFD3_k127_5868374_25 Ethanolamine utilisation protein EutN/carboxysome K04028 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.0000000000000000009633 89.0
HFD3_k127_5868374_26 BMC domain - - - 0.00000000000000006191 88.0
HFD3_k127_5868374_27 - - - - 0.00000000000006001 81.0
HFD3_k127_5868374_28 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.00000000007622 71.0
HFD3_k127_5868374_29 PFAM Ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.0000000003455 64.0
HFD3_k127_5868374_3 Aldehyde dehydrogenase family K04021,K13922 GO:0003674,GO:0003824,GO:0004029,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007207 496.0
HFD3_k127_5868374_4 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 482.0
HFD3_k127_5868374_5 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 451.0
HFD3_k127_5868374_6 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008183 437.0
HFD3_k127_5868374_7 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005395 419.0
HFD3_k127_5868374_8 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 384.0
HFD3_k127_5868374_9 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008503 364.0
HFD3_k127_5887389_0 E1-E2 ATPase K01534 - 3.6.3.3,3.6.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005586 541.0
HFD3_k127_5887389_1 cytochrome C peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 500.0
HFD3_k127_5887389_10 ABC-type transport system involved in multi-copper enzyme maturation permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001047 277.0
HFD3_k127_5887389_12 N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000004368 226.0
HFD3_k127_5887389_13 ATP hydrolysis coupled proton transport - - - 0.0000000000000000000000000000000000006969 160.0
HFD3_k127_5887389_14 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.000000000000000000000000000000000003015 158.0
HFD3_k127_5887389_15 Predicted membrane protein (DUF2214) K08983 - - 0.0000000000000000000000000000000001399 141.0
HFD3_k127_5887389_16 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.000000000000000000000000000000744 127.0
HFD3_k127_5887389_17 - - - - 0.0000000000000000000000001316 113.0
HFD3_k127_5887389_18 DoxX K15977 - - 0.0000000000000000000000007823 108.0
HFD3_k127_5887389_19 - - - - 0.000000000000000000005638 109.0
HFD3_k127_5887389_2 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 417.0
HFD3_k127_5887389_20 ferredoxin-NADP+ reductase activity - - - 0.00000000000000000003882 107.0
HFD3_k127_5887389_21 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000021 97.0
HFD3_k127_5887389_22 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 - 3.1.1.85 0.0000000000000001673 94.0
HFD3_k127_5887389_23 COG2217 Cation transport ATPase K01534 - 3.6.3.3,3.6.3.5 0.00000000000001646 75.0
HFD3_k127_5887389_24 Peptidase M48 - - - 0.00000000000003755 88.0
HFD3_k127_5887389_26 - - - - 0.00000000002783 74.0
HFD3_k127_5887389_27 cellulase activity - - - 0.00000000124 74.0
HFD3_k127_5887389_28 GDSL-like lipase acylhydrolase - - - 0.00000001155 67.0
HFD3_k127_5887389_29 ATPase associated with various cellular activities AAA_5 - - - 0.000002034 58.0
HFD3_k127_5887389_3 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 406.0
HFD3_k127_5887389_30 Domain of Unknown Function (DUF1080) - - - 0.000003366 57.0
HFD3_k127_5887389_31 alpha-L-arabinofuranosidase - - - 0.000007283 60.0
HFD3_k127_5887389_32 dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00002373 57.0
HFD3_k127_5887389_4 AlkA N-terminal domain K13529 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006538 414.0
HFD3_k127_5887389_5 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 404.0
HFD3_k127_5887389_6 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003743 429.0
HFD3_k127_5887389_7 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008609 365.0
HFD3_k127_5887389_8 Arginase family K01476 - 3.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 367.0
HFD3_k127_5887389_9 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 354.0
HFD3_k127_5887597_0 ABC transporter K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 486.0
HFD3_k127_5887597_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 503.0
HFD3_k127_5887597_10 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000000004703 85.0
HFD3_k127_5887597_11 Putative addiction module component - - - 0.00000001408 61.0
HFD3_k127_5887597_12 cytoplasmic translation - - - 0.0003146 50.0
HFD3_k127_5887597_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008123 322.0
HFD3_k127_5887597_3 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004799 281.0
HFD3_k127_5887597_4 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000003757 214.0
HFD3_k127_5887597_5 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.00000000000000000000000000000000000000000000000000003369 209.0
HFD3_k127_5887597_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000006566 160.0
HFD3_k127_5887597_7 oligosaccharyl transferase activity - - - 0.00000000000000000005859 107.0
HFD3_k127_5887597_8 Metallo-beta-lactamase superfamily - - - 0.0000000000000000002452 98.0
HFD3_k127_5887597_9 oligosaccharyl transferase activity - - - 0.00000000000000001217 99.0
HFD3_k127_5906516_0 Arginyl tRNA synthetase N terminal dom K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 442.0
HFD3_k127_5906516_1 tRNA nucleotidyltransferase domain 2 putative K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 394.0
HFD3_k127_5906516_10 PFAM HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000002028 235.0
HFD3_k127_5906516_11 von Willebrand factor type A domain K07114 - - 0.0000000000000000000000000000000000000000000002688 190.0
HFD3_k127_5906516_12 Oxygen tolerance - - - 0.000000000000000000000000000000000000001217 172.0
HFD3_k127_5906516_13 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 - 0.00000000000000000000000000009708 123.0
HFD3_k127_5906516_14 - - - - 0.0000000000000000001425 100.0
HFD3_k127_5906516_15 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000153 79.0
HFD3_k127_5906516_16 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) - - - 0.000000002872 64.0
HFD3_k127_5906516_17 Zn-ribbon protein possibly nucleic acid-binding K07164 - - 0.0008178 50.0
HFD3_k127_5906516_18 Psort location CytoplasmicMembrane, score - - - 0.0009658 51.0
HFD3_k127_5906516_2 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 318.0
HFD3_k127_5906516_3 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001246 308.0
HFD3_k127_5906516_4 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002962 276.0
HFD3_k127_5906516_5 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001566 259.0
HFD3_k127_5906516_6 Carbon-nitrogen hydrolase K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001321 261.0
HFD3_k127_5906516_7 PFAM AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000006791 265.0
HFD3_k127_5906516_8 von Willebrand factor (vWF) type A domain K07114,K12511 - - 0.0000000000000000000000000000000000000000000000000000000000000000003783 253.0
HFD3_k127_5906516_9 Polyprenyl synthetase K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000563 232.0
HFD3_k127_6063162_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 2.039e-231 734.0
HFD3_k127_6063162_1 elongation factor Tu domain 2 protein K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 619.0
HFD3_k127_6063162_10 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000009978 153.0
HFD3_k127_6063162_11 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000313 150.0
HFD3_k127_6063162_12 Yqey-like protein K09117 - - 0.0000000000000000000000000000005907 128.0
HFD3_k127_6063162_13 MgtC family K07507 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000007281 128.0
HFD3_k127_6063162_14 Glycosyl transferase family group 2 - - - 0.00000000000000001927 96.0
HFD3_k127_6063162_15 Type IV Pilus-assembly protein W K02672 - - 0.000000000000002057 89.0
HFD3_k127_6063162_16 Unextendable partial coding region - - - 0.0000000002637 63.0
HFD3_k127_6063162_17 - - - - 0.0000001519 55.0
HFD3_k127_6063162_18 N-terminal domain of cytochrome oxidase-cbb3, FixP K00406 - - 0.00000274 55.0
HFD3_k127_6063162_19 Prokaryotic N-terminal methylation motif K02458,K02671 - - 0.000008862 57.0
HFD3_k127_6063162_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 419.0
HFD3_k127_6063162_20 TIGRFAM prepilin-type N-terminal cleavage methylation domain K02246,K08084 - - 0.0002257 53.0
HFD3_k127_6063162_3 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 330.0
HFD3_k127_6063162_4 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 312.0
HFD3_k127_6063162_5 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004323 262.0
HFD3_k127_6063162_6 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000004291 265.0
HFD3_k127_6063162_7 phosphoserine phosphatase activity K01768,K07315 - 3.1.3.3,4.6.1.1 0.0000000000000000000000000000000000000000000000000000000008748 227.0
HFD3_k127_6063162_8 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000001584 211.0
HFD3_k127_6063162_9 protein secretion K02460 - - 0.0000000000000000000000000000000000000000000000000000008239 212.0
HFD3_k127_6097054_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 9.548e-205 655.0
HFD3_k127_6097054_1 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003464 557.0
HFD3_k127_6097054_10 domain, Protein - - - 0.000000000000000002551 89.0
HFD3_k127_6097054_11 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000003193 88.0
HFD3_k127_6097054_12 - - - - 0.00000000000002277 80.0
HFD3_k127_6097054_13 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000007486 74.0
HFD3_k127_6097054_14 C-terminal domain of CHU protein family - - - 0.0000000000005987 83.0
HFD3_k127_6097054_15 Galactose oxidase, central domain - - - 0.000000000001116 82.0
HFD3_k127_6097054_16 signal transduction histidine kinase K07636 - 2.7.13.3 0.000000000003105 79.0
HFD3_k127_6097054_18 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000002533 60.0
HFD3_k127_6097054_19 Galactose oxidase, central domain K14966 - - 0.0000001225 65.0
HFD3_k127_6097054_2 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 552.0
HFD3_k127_6097054_20 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000001363 65.0
HFD3_k127_6097054_21 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000001763 62.0
HFD3_k127_6097054_22 Tfp pilus assembly protein FimT K08084,K08085 - - 0.000003158 55.0
HFD3_k127_6097054_23 Tetratricopeptide TPR_2 repeat protein - - - 0.000003267 61.0
HFD3_k127_6097054_24 type IV pilus modification protein PilV K02458,K02671 - - 0.0008616 51.0
HFD3_k127_6097054_3 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 516.0
HFD3_k127_6097054_4 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004941 432.0
HFD3_k127_6097054_5 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007757 385.0
HFD3_k127_6097054_6 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 325.0
HFD3_k127_6097054_7 Two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000005607 258.0
HFD3_k127_6097054_8 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 - 0.000000000000000000000000000000000000000000000000000001208 208.0
HFD3_k127_6097054_9 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000004867 139.0
HFD3_k127_6142116_0 Domains REC, sigma54 interaction, HTH8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 398.0
HFD3_k127_6142116_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K02405 - - 0.000000000000000000000000000000000000000000000000000000001944 209.0
HFD3_k127_6142116_2 Belongs to the ParA family K04562 - - 0.00000000000000000000000000000000000000000000000000000004836 212.0
HFD3_k127_6142116_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000004453 215.0
HFD3_k127_6142116_4 PFAM ATP-binding region ATPase domain protein K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000005776 198.0
HFD3_k127_6142116_5 Serine phosphatase RsbU regulator of sigma subunit K07315 - 3.1.3.3 0.000000000000000000000000000000000001937 160.0
HFD3_k127_6142116_6 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000004137 128.0
HFD3_k127_6142116_7 response regulator receiver K02490 - - 0.00000000000000009332 87.0
HFD3_k127_6142116_8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563,K13626 - - 0.000000000000001011 79.0
HFD3_k127_621669_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 492.0
HFD3_k127_621669_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005288 297.0
HFD3_k127_621669_10 Methionine biosynthesis protein MetW - - - 0.0000000003331 71.0
HFD3_k127_621669_11 Tetratricopeptide repeat - - - 0.000001958 60.0
HFD3_k127_621669_12 Periplasmic component of the Tol biopolymer transport system - - - 0.00008644 55.0
HFD3_k127_621669_2 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001613 267.0
HFD3_k127_621669_3 Metal dependent phosphohydrolases with conserved 'HD' motif. K09163 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001206 253.0
HFD3_k127_621669_4 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008674 254.0
HFD3_k127_621669_5 Histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000002687 197.0
HFD3_k127_621669_6 Signal transduction histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000002462 169.0
HFD3_k127_621669_7 PFAM response regulator receiver K02483,K07658,K07668 - - 0.000000000000000000000000000000006091 149.0
HFD3_k127_621669_8 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530,K05788 - - 0.0000000000000000000000000006076 116.0
HFD3_k127_621669_9 protein involved in tolerance to divalent cations K03926 - - 0.0000000000000000000001202 108.0
HFD3_k127_6237085_0 SMART Integrin alpha beta-propellor repeat protein - - - 8.854e-230 761.0
HFD3_k127_6237085_1 Cellulase (glycosyl hydrolase family 5) K05350 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006184 634.0
HFD3_k127_6237085_10 Endonuclease Exonuclease Phosphatase - - - 0.000000000000000000000468 111.0
HFD3_k127_6237085_11 - - - - 0.000000000000000009336 88.0
HFD3_k127_6237085_13 peptidase activity, acting on L-amino acid peptides K01337,K20276 - 3.4.21.50 0.00000000376 71.0
HFD3_k127_6237085_14 photosystem II stabilization K02237 - - 0.00000009953 61.0
HFD3_k127_6237085_15 Sigma-70, region 4 K03088 - - 0.0000127 59.0
HFD3_k127_6237085_16 endonuclease activity K07451 - - 0.0005841 49.0
HFD3_k127_6237085_2 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006394 588.0
HFD3_k127_6237085_3 FAD linked oxidases, C-terminal domain K00102,K00104 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.2.4,1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 461.0
HFD3_k127_6237085_4 Domain of unknown function (DUF4301) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 389.0
HFD3_k127_6237085_5 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 364.0
HFD3_k127_6237085_6 N,N-dimethylaniline monooxygenase activity - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005602 277.0
HFD3_k127_6237085_7 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000561 246.0
HFD3_k127_6237085_8 Serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000002102 200.0
HFD3_k127_6237085_9 PFAM FAD linked oxidase domain protein K00104,K11472 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.3.15 0.00000000000000000000000000000000000000007114 174.0
HFD3_k127_6327926_0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 499.0
HFD3_k127_6327926_1 Proton-conducting membrane transporter K12141 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 396.0
HFD3_k127_6327926_10 polysaccharide catabolic process K01179,K01218 - 3.2.1.4,3.2.1.78 0.0000006205 64.0
HFD3_k127_6327926_2 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 382.0
HFD3_k127_6327926_3 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 314.0
HFD3_k127_6327926_4 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005352 299.0
HFD3_k127_6327926_5 thymidine kinase activity K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000002431 244.0
HFD3_k127_6327926_6 Proton-conducting membrane transporter K12137 - - 0.0000000000000000000000000000000000000000000000000000000111 209.0
HFD3_k127_6327926_7 hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000000000000000000000000000009719 199.0
HFD3_k127_6327926_8 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.00000000000000000000000000000000000000000000000002033 207.0
HFD3_k127_6327926_9 Belongs to the peptidase S8 family K13276 - - 0.0000000003683 74.0
HFD3_k127_6366089_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 1.023e-255 821.0
HFD3_k127_6366089_1 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 445.0
HFD3_k127_6366089_2 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 359.0
HFD3_k127_6366089_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000003875 241.0
HFD3_k127_6366089_4 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000003256 213.0
HFD3_k127_6366089_5 M6 family metalloprotease domain protein - - - 0.00000000000000000000000000000000000000000000000000001251 216.0
HFD3_k127_6366089_6 Peptidase M56 - - - 0.0000000000000000000000000000000003436 147.0
HFD3_k127_6366089_7 NlpC/P60 family K20742,K21471 - 3.4.14.13 0.0000000000000000000000008941 123.0
HFD3_k127_6366089_8 PFAM Peptidase M23 K21471 - - 0.0000000000004044 82.0
HFD3_k127_6430067_0 Protein of unknown function, DUF255 K06888 - - 1.079e-198 641.0
HFD3_k127_6430067_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 412.0
HFD3_k127_6430067_10 Nitroreductase family - - - 0.000000000000000000000000000000000008997 151.0
HFD3_k127_6430067_11 Calcineurin-like phosphoesterase superfamily domain K03547 - - 0.000000000000000000000000000000008332 146.0
HFD3_k127_6430067_12 Belongs to the peptidase S41A family K06399 - 3.4.21.116 0.0000000000000000000000000006841 131.0
HFD3_k127_6430067_13 Sigma-70, region 4 K03088 - - 0.00000000000000000000000007767 115.0
HFD3_k127_6430067_14 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.000000000000000000000804 111.0
HFD3_k127_6430067_15 Mut7-C RNAse domain K09122 - - 0.000000000000000006223 89.0
HFD3_k127_6430067_16 Transposase - - - 0.000000000000000007521 95.0
HFD3_k127_6430067_17 Thioesterase-like superfamily K07107 - - 0.0000000000000002331 93.0
HFD3_k127_6430067_18 FlgD Ig-like domain - - - 0.0000000000004531 83.0
HFD3_k127_6430067_19 AAA domain - - - 0.0000000000006731 84.0
HFD3_k127_6430067_2 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 422.0
HFD3_k127_6430067_20 AAA domain - - - 0.00001281 60.0
HFD3_k127_6430067_21 Glycosyl transferase family 41 - - - 0.00009548 53.0
HFD3_k127_6430067_3 Cytochrome c biogenesis protein transmembrane region K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007062 427.0
HFD3_k127_6430067_4 Zn-dependent proteases and their inactivated homologs K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 325.0
HFD3_k127_6430067_5 Cytochrome c3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002298 269.0
HFD3_k127_6430067_6 Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000001203 245.0
HFD3_k127_6430067_7 Glycosyltransferase like family 2 K07011 - - 0.0000000000000000000000000000000000000000000000000000272 199.0
HFD3_k127_6430067_8 peptidase U62, modulator of DNA gyrase K03568 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 0.0000000000000000000000000000000000000000000000004166 178.0
HFD3_k127_6430067_9 Sterol carrier protein domain - - - 0.000000000000000000000000000000000000000000001016 182.0
HFD3_k127_6458829_0 GTP-binding protein TypA K06207 - - 3.659e-251 812.0
HFD3_k127_6458829_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006808 531.0
HFD3_k127_6458829_10 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000002852 252.0
HFD3_k127_6458829_11 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003887 273.0
HFD3_k127_6458829_12 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000005409 229.0
HFD3_k127_6458829_13 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000576 219.0
HFD3_k127_6458829_14 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000009078 217.0
HFD3_k127_6458829_15 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000000161 209.0
HFD3_k127_6458829_16 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000225 196.0
HFD3_k127_6458829_17 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000004053 193.0
HFD3_k127_6458829_18 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000005591 189.0
HFD3_k127_6458829_19 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000003805 184.0
HFD3_k127_6458829_2 Multicopper oxidase K06324 - 1.16.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 481.0
HFD3_k127_6458829_20 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000006769 183.0
HFD3_k127_6458829_21 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000003889 189.0
HFD3_k127_6458829_22 Forms part of the polypeptide exit tunnel K02926 - - 0.0000000000000000000000000000000000000000000000011 181.0
HFD3_k127_6458829_23 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000001203 163.0
HFD3_k127_6458829_24 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000005552 143.0
HFD3_k127_6458829_25 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000005975 141.0
HFD3_k127_6458829_26 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.0000000000000000000000000000000001101 140.0
HFD3_k127_6458829_27 PFAM ribosomal protein L17 K02879 - - 0.0000000000000000000000000000000007053 138.0
HFD3_k127_6458829_28 Response regulator receiver domain - - - 0.000000000000000000000000000000003423 150.0
HFD3_k127_6458829_29 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000004988 136.0
HFD3_k127_6458829_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 391.0
HFD3_k127_6458829_30 Serine phosphatase RsbU regulator of sigma subunit K07315 - 3.1.3.3 0.0000000000000000000000000000001621 138.0
HFD3_k127_6458829_31 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000215 142.0
HFD3_k127_6458829_32 Glycosyl hydrolase-like 10 - - - 0.000000000000000000000000000006763 134.0
HFD3_k127_6458829_33 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000305 121.0
HFD3_k127_6458829_34 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000005604 122.0
HFD3_k127_6458829_35 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000002485 114.0
HFD3_k127_6458829_36 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000002293 103.0
HFD3_k127_6458829_37 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000004941 90.0
HFD3_k127_6458829_38 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000006497 101.0
HFD3_k127_6458829_39 Ribosomal protein L30 K02907 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000001522 72.0
HFD3_k127_6458829_4 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 374.0
HFD3_k127_6458829_40 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000004609 66.0
HFD3_k127_6458829_41 Ribosomal protein L36 K02919 - - 0.0000000001405 67.0
HFD3_k127_6458829_42 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000000003769 67.0
HFD3_k127_6458829_43 - - - - 0.0006739 50.0
HFD3_k127_6458829_5 peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005797 378.0
HFD3_k127_6458829_6 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 309.0
HFD3_k127_6458829_7 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000583 316.0
HFD3_k127_6458829_8 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004962 275.0
HFD3_k127_6458829_9 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002355 275.0
HFD3_k127_6471446_0 OPT oligopeptide transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 561.0
HFD3_k127_6471446_1 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007469 552.0
HFD3_k127_6471446_10 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000001426 257.0
HFD3_k127_6471446_11 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000000000009299 203.0
HFD3_k127_6471446_12 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.0000000000000000000000000000000000000000000000000571 203.0
HFD3_k127_6471446_13 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.000000000000000000000000000000000000000000000004204 194.0
HFD3_k127_6471446_14 Cytochrome c - - - 0.0000000000000000000000000000000000000000000007743 173.0
HFD3_k127_6471446_15 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000133 157.0
HFD3_k127_6471446_16 dihydroorotate dehydrogenase K02823 - - 0.00000000000000000000000000000001978 147.0
HFD3_k127_6471446_17 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000005459 123.0
HFD3_k127_6471446_18 - - - - 0.0000000000000000000000002459 112.0
HFD3_k127_6471446_19 HNH nucleases - - - 0.00000000000000000000000366 109.0
HFD3_k127_6471446_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 457.0
HFD3_k127_6471446_20 nucleotide catabolic process K05996 - 3.4.17.18 0.0000000214 67.0
HFD3_k127_6471446_21 polysaccharide biosynthetic process - - - 0.0001288 50.0
HFD3_k127_6471446_22 TonB dependent receptor K02014 - - 0.0002724 53.0
HFD3_k127_6471446_3 Polysaccharide biosynthesis protein K15856 - 1.1.1.281 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 417.0
HFD3_k127_6471446_4 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 405.0
HFD3_k127_6471446_5 PFAM glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005039 390.0
HFD3_k127_6471446_6 serine protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 384.0
HFD3_k127_6471446_7 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 300.0
HFD3_k127_6471446_8 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005628 284.0
HFD3_k127_6471446_9 Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000008855 279.0
HFD3_k127_6534638_0 AcrB/AcrD/AcrF family K03296 - - 1.254e-318 1007.0
HFD3_k127_6534638_1 TonB-dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 374.0
HFD3_k127_6534638_10 PHP-associated - - - 0.0000000000000000000000000001696 133.0
HFD3_k127_6534638_11 PFAM regulatory protein TetR - - - 0.0000000000000000000000000008244 121.0
HFD3_k127_6534638_12 positive regulation of type IV pilus biogenesis K07343 - - 0.00000000000000001299 98.0
HFD3_k127_6534638_13 endonuclease activity K07451 - - 0.0000000001062 64.0
HFD3_k127_6534638_2 A G-specific K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007183 301.0
HFD3_k127_6534638_3 Prolyl oligopeptidase family K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004337 258.0
HFD3_k127_6534638_4 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000299 220.0
HFD3_k127_6534638_5 COGs COG2912 conserved - - - 0.00000000000000000000000000000000000000000000000000001323 200.0
HFD3_k127_6534638_6 COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ) - - - 0.000000000000000000000000000000000000000000000000003001 196.0
HFD3_k127_6534638_7 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000002034 186.0
HFD3_k127_6534638_8 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000004616 184.0
HFD3_k127_6534638_9 - - - - 0.000000000000000000000000000000000001015 160.0
HFD3_k127_654261_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 457.0
HFD3_k127_654261_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 450.0
HFD3_k127_654261_10 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.00000000000000000000000000000000000000007823 163.0
HFD3_k127_654261_11 MlaD protein K02067 - - 0.0000000000000000000000000000000001213 144.0
HFD3_k127_654261_12 - - - - 0.00000000000000000007041 93.0
HFD3_k127_654261_13 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000006771 81.0
HFD3_k127_654261_14 Helix-turn-helix domain - - - 0.000000003693 64.0
HFD3_k127_654261_15 Large exoproteins involved in heme utilization or adhesion K15125 - - 0.00001405 51.0
HFD3_k127_654261_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 342.0
HFD3_k127_654261_3 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 323.0
HFD3_k127_654261_4 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001089 256.0
HFD3_k127_654261_5 TIGR00255 family - - - 0.00000000000000000000000000000000000000000000000000000000000000005152 234.0
HFD3_k127_654261_6 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000001133 196.0
HFD3_k127_654261_7 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.0000000000000000000000000000000000000000000000007065 189.0
HFD3_k127_654261_8 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000297 196.0
HFD3_k127_654261_9 Aminoacyl-tRNA editing domain K01284 - 3.4.15.5 0.000000000000000000000000000000000000000000001624 182.0
HFD3_k127_6554541_0 PFAM glycosyl transferase family 35 K00688 - 2.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 608.0
HFD3_k127_6554541_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 538.0
HFD3_k127_6554541_10 Cys/Met metabolism PLP-dependent enzyme K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000005164 270.0
HFD3_k127_6554541_11 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000146 252.0
HFD3_k127_6554541_12 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000002022 238.0
HFD3_k127_6554541_13 Domain of unknown function (DUF4396) - - - 0.000000000000000000000000000000000000000000000000000001976 206.0
HFD3_k127_6554541_14 Belongs to the peptidase S11 family K01286,K07258,K07262 GO:0000003,GO:0000270,GO:0000910,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006022,GO:0006508,GO:0006807,GO:0007049,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016043,GO:0016787,GO:0019538,GO:0019954,GO:0022402,GO:0022414,GO:0030203,GO:0032505,GO:0042221,GO:0042493,GO:0042597,GO:0043093,GO:0043170,GO:0044238,GO:0044464,GO:0045229,GO:0050896,GO:0051301,GO:0070011,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0140096,GO:1901135,GO:1901564 3.4.16.4 0.000000000000000000000000000000000000000000000000004591 192.0
HFD3_k127_6554541_15 Belongs to the peptidase S8 family K17734 - - 0.00000000000000000000000000000000000000000000007977 196.0
HFD3_k127_6554541_16 NUDIX domain - - - 0.000000000000000000000000000000000000000002607 162.0
HFD3_k127_6554541_17 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000001839 161.0
HFD3_k127_6554541_18 alpha beta - - - 0.00000000000000000000000000000000000001943 157.0
HFD3_k127_6554541_19 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000003488 154.0
HFD3_k127_6554541_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004834 515.0
HFD3_k127_6554541_20 Cytochrome c - - - 0.0000000000000000000000000000000000357 145.0
HFD3_k127_6554541_21 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000001175 143.0
HFD3_k127_6554541_22 PFAM AIG2 family protein - - - 0.00000000000000000000000000002657 124.0
HFD3_k127_6554541_23 Conserved repeat domain - - - 0.0000000000000000000001448 112.0
HFD3_k127_6554541_24 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000154 110.0
HFD3_k127_6554541_25 Lamin Tail Domain - - - 0.0000000000000000000003089 106.0
HFD3_k127_6554541_26 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000007623 108.0
HFD3_k127_6554541_27 Acetyltransferase (GNAT) family - - - 0.00000000000000000003651 101.0
HFD3_k127_6554541_28 Predicted membrane protein (DUF2079) - - - 0.000000000000002638 89.0
HFD3_k127_6554541_29 response regulator, receiver K02030,K13040 - 2.7.13.3 0.000000000002445 80.0
HFD3_k127_6554541_3 SMART Tetratricopeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 391.0
HFD3_k127_6554541_30 Bacterial protein of unknown function (DUF885) - - - 0.00000000003355 78.0
HFD3_k127_6554541_31 pectinesterase activity K10117 - - 0.00000003094 67.0
HFD3_k127_6554541_32 extracellular matrix structural constituent - - - 0.000002728 58.0
HFD3_k127_6554541_33 Sigma-54 interaction domain - - - 0.0000755 52.0
HFD3_k127_6554541_34 - - - - 0.000144 50.0
HFD3_k127_6554541_4 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 338.0
HFD3_k127_6554541_5 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 329.0
HFD3_k127_6554541_6 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 321.0
HFD3_k127_6554541_7 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003376 316.0
HFD3_k127_6554541_8 benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001461 292.0
HFD3_k127_6554541_9 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000002549 282.0
HFD3_k127_6576440_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 6.581e-203 664.0
HFD3_k127_6576440_1 Ftsk_gamma K03466 GO:0000920,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006950,GO:0006970,GO:0007059,GO:0008094,GO:0008150,GO:0009628,GO:0009651,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0015616,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033676,GO:0042221,GO:0042623,GO:0042802,GO:0043085,GO:0043565,GO:0044093,GO:0044425,GO:0044459,GO:0044464,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051301,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070887,GO:0071236,GO:0071944,GO:0080090,GO:0097159,GO:0140097,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009811 458.0
HFD3_k127_6576440_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 383.0
HFD3_k127_6576440_3 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000005382 164.0
HFD3_k127_6576440_4 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000057 169.0
HFD3_k127_6576440_5 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000008048 140.0
HFD3_k127_6576440_6 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000001383 121.0
HFD3_k127_6576440_7 outer membrane assembly lipoprotein YfiO K05807 - - 0.00000004669 65.0
HFD3_k127_6645121_0 Right handed beta helix region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 655.0
HFD3_k127_6645121_1 Conserved repeat domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 616.0
HFD3_k127_6645121_10 Binds the 23S rRNA K02909 GO:0008150,GO:0040007 - 0.00000000000000000008286 94.0
HFD3_k127_6645121_11 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00001187 53.0
HFD3_k127_6645121_12 Integrin alpha (beta-propellor repeats). - - - 0.00001383 59.0
HFD3_k127_6645121_13 Pectinesterase K01051 - 3.1.1.11 0.00008457 57.0
HFD3_k127_6645121_14 Right handed beta helix region - - - 0.0003347 55.0
HFD3_k127_6645121_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005191 467.0
HFD3_k127_6645121_3 translation release factor activity K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007363 422.0
HFD3_k127_6645121_4 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001495 300.0
HFD3_k127_6645121_5 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003458 268.0
HFD3_k127_6645121_6 Protein of unknown function (DUF1385) - - - 0.000000000000000000000000000000000000000000000000000000000000000000167 244.0
HFD3_k127_6645121_7 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006464,GO:0006479,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0010468,GO:0016043,GO:0016740,GO:0016741,GO:0018364,GO:0019222,GO:0019538,GO:0022411,GO:0032259,GO:0032984,GO:0034641,GO:0034645,GO:0036009,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043414,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.297 0.00000000000000000000000000000000000000000000000000004654 200.0
HFD3_k127_6645121_8 Methyltransferase - - - 0.00000000000000000000000000000000000000000001023 181.0
HFD3_k127_6645121_9 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000001525 124.0
HFD3_k127_6669380_0 3-beta hydroxysteroid dehydrogenase/isomerase family K01784,K10011,K12449 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006040,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016741,GO:0016742,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0022607,GO:0033319,GO:0033320,GO:0034214,GO:0034641,GO:0034654,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046349,GO:0046483,GO:0046677,GO:0048037,GO:0048040,GO:0050662,GO:0050896,GO:0051259,GO:0051287,GO:0055086,GO:0055114,GO:0065003,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:0099618,GO:0099619,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:2001313,GO:2001315 1.1.1.305,2.1.2.13,5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 351.0
HFD3_k127_6669380_1 Monogalactosyldiacylglycerol (MGDG) synthase K03429 - 2.4.1.315 0.00000000000000000000000000000000000000000000000000000000000000000000000891 259.0
HFD3_k127_6669380_10 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000036 138.0
HFD3_k127_6669380_11 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000002026 112.0
HFD3_k127_6669380_12 Belongs to the UPF0109 family K06960 - - 0.00000000000002456 81.0
HFD3_k127_6669380_13 O-antigen ligase like membrane protein - - - 0.0000000005434 72.0
HFD3_k127_6669380_14 Uncharacterised protein family UPF0102 - - - 0.00000001143 61.0
HFD3_k127_6669380_15 Belongs to the glycosyl hydrolase 13 family - - - 0.00000002332 67.0
HFD3_k127_6669380_2 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000007877 256.0
HFD3_k127_6669380_3 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000000001738 219.0
HFD3_k127_6669380_4 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000005167 227.0
HFD3_k127_6669380_5 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000001372 207.0
HFD3_k127_6669380_6 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000000000000000745 210.0
HFD3_k127_6669380_7 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000001203 194.0
HFD3_k127_6669380_8 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000019 166.0
HFD3_k127_6669380_9 amino acid activation for nonribosomal peptide biosynthetic process K17713,K20952 - - 0.00000000000000000000000000000000000009872 164.0
HFD3_k127_6718320_0 beta-galactosidase activity K01224 - 3.2.1.89 0.0 1190.0
HFD3_k127_6718320_1 - - - - 2.841e-300 980.0
HFD3_k127_6718320_10 Transposase - - - 0.00000000006037 75.0
HFD3_k127_6718320_11 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.0002775 53.0
HFD3_k127_6718320_12 Parallel beta-helix repeats - - - 0.0004145 53.0
HFD3_k127_6718320_2 Glycosyl hydrolase family 1 K05350 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 555.0
HFD3_k127_6718320_3 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006434 288.0
HFD3_k127_6718320_4 CHAT domain - - - 0.0000000000000000000000000000000000000000000000000000000000001613 243.0
HFD3_k127_6718320_5 Glycosyl hydrolases family 17 - - - 0.000000000000000000000000000000000000000000000000000000005746 212.0
HFD3_k127_6718320_6 Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000001262 201.0
HFD3_k127_6718320_7 CHRD domain - - - 0.0000000000000000000000000000000000000000183 162.0
HFD3_k127_6718320_8 Hydrolase Family 16 - - - 0.000000000000000000000000000000000000009313 164.0
HFD3_k127_6718320_9 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000006687 145.0
HFD3_k127_6856007_0 Heat shock 70 kDa protein K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0018995,GO:0019219,GO:0019222,GO:0020003,GO:0022607,GO:0030430,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0033643,GO:0033646,GO:0033655,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043531,GO:0043656,GO:0043657,GO:0043933,GO:0044085,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0065010,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 3.957e-282 880.0
HFD3_k127_6856007_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 569.0
HFD3_k127_6856007_10 N-acetyl-alpha-D-glucosaminyl L-malate synthase K00754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 360.0
HFD3_k127_6856007_11 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 328.0
HFD3_k127_6856007_12 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005118 350.0
HFD3_k127_6856007_13 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 352.0
HFD3_k127_6856007_14 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006781 336.0
HFD3_k127_6856007_15 PFAM Mandelate racemase muconate lactonizing protein K19802 - 5.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008043 310.0
HFD3_k127_6856007_16 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 317.0
HFD3_k127_6856007_17 Domain of unknown function (DUF1731) K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008779 291.0
HFD3_k127_6856007_18 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001994 292.0
HFD3_k127_6856007_19 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase K01826 - 5.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000007588 250.0
HFD3_k127_6856007_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 526.0
HFD3_k127_6856007_20 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003272 241.0
HFD3_k127_6856007_21 Xylose isomerase domain protein TIM barrel K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000001579 233.0
HFD3_k127_6856007_22 ABC transporter K02003,K05685 - - 0.0000000000000000000000000000000000000000000000000000000000000007752 239.0
HFD3_k127_6856007_23 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000004506 225.0
HFD3_k127_6856007_24 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000002119 228.0
HFD3_k127_6856007_25 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000015 223.0
HFD3_k127_6856007_26 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000417 192.0
HFD3_k127_6856007_27 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000003152 208.0
HFD3_k127_6856007_28 COG0491 Zn-dependent hydrolases, including glyoxylases K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000004062 190.0
HFD3_k127_6856007_29 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.00000000000000000000000000000000000000000000000007862 181.0
HFD3_k127_6856007_3 metalloendopeptidase activity K01283 - 3.4.15.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 488.0
HFD3_k127_6856007_30 GlcNAc-PI de-N-acetylase K01463 - - 0.000000000000000000000000000000000000000000209 178.0
HFD3_k127_6856007_31 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000007258 177.0
HFD3_k127_6856007_32 Histidine kinase K14986 - 2.7.13.3 0.0000000000000000000000000000000000000009917 167.0
HFD3_k127_6856007_33 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.00000000000000000000000000000000000003251 165.0
HFD3_k127_6856007_34 PFAM MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000004224 146.0
HFD3_k127_6856007_35 Bacillithiol biosynthesis BshC K22136 - - 0.0000000000000000000000000000000000398 153.0
HFD3_k127_6856007_36 OmpA family K03640 - - 0.0000000000000000000000000000000287 132.0
HFD3_k127_6856007_37 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000004834 142.0
HFD3_k127_6856007_38 Molybdenum cofactor biosynthesis K03638,K03831 - 2.7.7.75 0.0000000000000000000000000000005719 139.0
HFD3_k127_6856007_39 Glutathione peroxidase K02199 - - 0.00000000000000000000000000000137 128.0
HFD3_k127_6856007_4 Belongs to the citrate synthase family K01647 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 386.0
HFD3_k127_6856007_40 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000002703 138.0
HFD3_k127_6856007_41 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000000002499 133.0
HFD3_k127_6856007_42 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000003736 112.0
HFD3_k127_6856007_43 Biopolymer transport protein ExbD/TolR K03560 - - 0.0000000000000000000001821 110.0
HFD3_k127_6856007_44 Outer membrane lipoprotein - - - 0.00000000000000000006358 103.0
HFD3_k127_6856007_45 TonB C terminal K03646,K03832 - - 0.000000000000005273 87.0
HFD3_k127_6856007_46 transferase activity, transferring glycosyl groups K20444 - - 0.0000000001511 74.0
HFD3_k127_6856007_47 - - - - 0.000000003449 66.0
HFD3_k127_6856007_48 Serine aminopeptidase, S33 K06889 - - 0.00000001126 66.0
HFD3_k127_6856007_5 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 381.0
HFD3_k127_6856007_6 TIGRFAM Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 375.0
HFD3_k127_6856007_7 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005827 364.0
HFD3_k127_6856007_8 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 376.0
HFD3_k127_6856007_9 PFAM Amidohydrolase 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 351.0
HFD3_k127_6856327_0 Domain in cystathionine beta-synthase and other proteins. K01697 - 4.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 486.0
HFD3_k127_6856327_1 PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein K01739,K01761 - 2.5.1.48,4.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 472.0
HFD3_k127_6856327_2 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000002024 248.0
HFD3_k127_6856327_3 Cytochrome c554 and c-prime - - - 0.000000000000000000000000002987 122.0
HFD3_k127_6856327_4 - - - - 0.00000001309 67.0
HFD3_k127_6964227_0 ABC-type dipeptide transport system periplasmic component K02035 - - 2.385e-203 660.0
HFD3_k127_6964227_1 5TM C-terminal transporter carbon starvation CstA K06200 - - 2.257e-200 642.0
HFD3_k127_6964227_10 Tryptophanyl-tRNA synthetase K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 366.0
HFD3_k127_6964227_11 ABC transporter permease K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 365.0
HFD3_k127_6964227_12 Glycosyl hydrolases family 16 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 310.0
HFD3_k127_6964227_13 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000412 301.0
HFD3_k127_6964227_14 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007355 286.0
HFD3_k127_6964227_15 Lytic transglycosylase catalytic K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009673 288.0
HFD3_k127_6964227_16 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000002258 244.0
HFD3_k127_6964227_17 Belongs to the pseudouridine synthase RsuA family K06178 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.22 0.0000000000000000000000000000000000000000000000000000003516 219.0
HFD3_k127_6964227_18 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000004685 185.0
HFD3_k127_6964227_19 long-chain fatty acid transport protein - - - 0.000000000000000000000000000000000000000000006197 178.0
HFD3_k127_6964227_2 PFAM Type II secretion system protein E K02454,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 531.0
HFD3_k127_6964227_20 PFAM peptidase M50 - - - 0.00000000000000000000000000000000000000002552 161.0
HFD3_k127_6964227_21 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000005308 159.0
HFD3_k127_6964227_22 Glycosyl hydrolases family 16 - - - 0.000000000000000000000000000000000000007725 158.0
HFD3_k127_6964227_23 Glycosyl hydrolases family 16 - - - 0.0000000000000000000000000000000009634 151.0
HFD3_k127_6964227_24 PFAM PEGA domain - - - 0.00000000000005365 86.0
HFD3_k127_6964227_25 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000006167 70.0
HFD3_k127_6964227_26 cellulase activity - - - 0.00000000005989 74.0
HFD3_k127_6964227_28 cell redox homeostasis - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000403 57.0
HFD3_k127_6964227_3 ABC transporter permease K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 452.0
HFD3_k127_6964227_4 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K01768,K07315 - 3.1.3.3,4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 468.0
HFD3_k127_6964227_5 Bacterial protein of unknown function (DUF853) K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 446.0
HFD3_k127_6964227_6 xyloglucan:xyloglucosyl transferase activity K01216,K07004 - 3.2.1.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 434.0
HFD3_k127_6964227_7 ROK family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 404.0
HFD3_k127_6964227_8 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 419.0
HFD3_k127_6964227_9 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 367.0
HFD3_k127_7213692_0 Prokaryotic cytochrome b561 - - - 0.0 1133.0
HFD3_k127_7213692_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1125.0
HFD3_k127_7213692_10 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 480.0
HFD3_k127_7213692_11 ABC transporter substrate-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 469.0
HFD3_k127_7213692_12 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 440.0
HFD3_k127_7213692_13 cellulose binding K00505 - 1.14.18.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007679 401.0
HFD3_k127_7213692_14 denitrification pathway K02569,K15876 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 393.0
HFD3_k127_7213692_15 ABC-type sugar transport systems, permease components K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006009 354.0
HFD3_k127_7213692_16 Cytochrome c554 and c-prime K03620 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 314.0
HFD3_k127_7213692_17 Transcriptional regulator K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 306.0
HFD3_k127_7213692_18 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000001324 264.0
HFD3_k127_7213692_19 Tyrosine recombinase XerD K04763 GO:0008150,GO:0040007 - 0.000000000000000000000000000000000000000000000000000000000003321 222.0
HFD3_k127_7213692_2 coagulation factor 5 8 type - - - 1.354e-280 908.0
HFD3_k127_7213692_20 Cytochrome c554 and c-prime K03620 - - 0.0000000000000000000000000000000000000000000000000186 204.0
HFD3_k127_7213692_21 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000008628 189.0
HFD3_k127_7213692_22 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000003119 177.0
HFD3_k127_7213692_23 Cytochrome b(C-terminal)/b6/petD K00412 - - 0.0000000000000000000000000000000000000000005528 174.0
HFD3_k127_7213692_24 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.17.1.8 0.000000000000000000000000000000000000000002051 175.0
HFD3_k127_7213692_25 Bifunctional purine biosynthesis protein PurH K00602 GO:0003674,GO:0003824,GO:0004643,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000001138 154.0
HFD3_k127_7213692_26 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.000000000000000000000000000000000000001363 162.0
HFD3_k127_7213692_27 Cold shock K03704 - - 0.000000000000000002116 98.0
HFD3_k127_7213692_28 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 - - 0.00000000000000001465 99.0
HFD3_k127_7213692_29 amine dehydrogenase activity K08282,K08884 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009405,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010565,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031667,GO:0031668,GO:0031669,GO:0032091,GO:0033554,GO:0036211,GO:0042304,GO:0042594,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043393,GO:0043412,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051100,GO:0051704,GO:0051716,GO:0062012,GO:0062014,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.0000000000000002842 92.0
HFD3_k127_7213692_3 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 9.414e-246 805.0
HFD3_k127_7213692_30 5'-nucleotidase - - - 0.0000000000000004261 94.0
HFD3_k127_7213692_31 PFAM Rieske 2Fe-2S K02636 - 1.10.9.1 0.000000000000003633 88.0
HFD3_k127_7213692_32 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000009448 85.0
HFD3_k127_7213692_33 acyl-phosphate glycerol-3-phosphate acyltransferase activity K08591 - 2.3.1.15 0.00000000000007554 79.0
HFD3_k127_7213692_34 Bacterial Ig-like domain - - - 0.0000000000001334 84.0
HFD3_k127_7213692_35 PFAM NHL repeat containing protein - - - 0.00000000006833 74.0
HFD3_k127_7213692_36 Peptidoglycan-synthase activator LpoB - - - 0.00000000008082 76.0
HFD3_k127_7213692_37 - - - - 0.00000001973 65.0
HFD3_k127_7213692_38 6 heme-binding sites - - - 0.0000001343 63.0
HFD3_k127_7213692_39 Tetratricopeptide repeat - - - 0.000005366 59.0
HFD3_k127_7213692_4 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.566e-222 717.0
HFD3_k127_7213692_40 Binds directly to 16S ribosomal RNA K02968 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.00001029 52.0
HFD3_k127_7213692_5 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 613.0
HFD3_k127_7213692_6 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 626.0
HFD3_k127_7213692_7 Putative glucoamylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 588.0
HFD3_k127_7213692_8 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009271 595.0
HFD3_k127_7213692_9 Cytochrome b subunit of formate dehydrogenase-like protein - GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0006790,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016002,GO:0016043,GO:0016491,GO:0016667,GO:0017144,GO:0019748,GO:0020037,GO:0022607,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044272,GO:0044550,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051259,GO:0051260,GO:0055114,GO:0065003,GO:0070206,GO:0070207,GO:0070813,GO:0070814,GO:0071840,GO:0097159,GO:1901363,GO:1903136 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000558 548.0
HFD3_k127_7215316_0 cytochrome C peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 483.0
HFD3_k127_7215316_1 Putative modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 398.0
HFD3_k127_7215316_2 Bacterial transcriptional repressor C-terminal K09017 - - 0.000000000000000000000000000000000000000000000000000002258 198.0
HFD3_k127_7215316_3 transposition, DNA-mediated K02342 - 2.7.7.7 0.00000000000000000000000000000000000004991 156.0
HFD3_k127_7215316_4 Evidence 5 No homology to any previously reported sequences - - - 0.00000003723 67.0
HFD3_k127_7215316_5 P-type ATPase K17686,K19597 GO:0000041,GO:0000139,GO:0000166,GO:0003674,GO:0003824,GO:0004008,GO:0005215,GO:0005375,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005770,GO:0005794,GO:0005802,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0006873,GO:0006874,GO:0006875,GO:0006878,GO:0008144,GO:0008150,GO:0008324,GO:0009987,GO:0010035,GO:0010038,GO:0012505,GO:0015075,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015677,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019725,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030554,GO:0031090,GO:0031224,GO:0031226,GO:0031410,GO:0031982,GO:0031984,GO:0032553,GO:0032555,GO:0032559,GO:0032588,GO:0034220,GO:0035434,GO:0035639,GO:0036094,GO:0042221,GO:0042592,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0043682,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0046688,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051208,GO:0051234,GO:0051235,GO:0055065,GO:0055070,GO:0055074,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0060003,GO:0065007,GO:0065008,GO:0071944,GO:0072503,GO:0072507,GO:0090662,GO:0097159,GO:0097367,GO:0097708,GO:0098588,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0098791,GO:0099131,GO:0099132,GO:1901265,GO:1901363 3.6.3.54 0.00003453 51.0
HFD3_k127_7215316_6 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.00003763 56.0
HFD3_k127_7239417_0 Ser Thr phosphatase family protein - - - 2.809e-277 906.0
HFD3_k127_7239417_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007121 505.0
HFD3_k127_7239417_10 NAD dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 331.0
HFD3_k127_7239417_11 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009331 337.0
HFD3_k127_7239417_12 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 340.0
HFD3_k127_7239417_13 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007135 336.0
HFD3_k127_7239417_14 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 327.0
HFD3_k127_7239417_15 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 328.0
HFD3_k127_7239417_16 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 302.0
HFD3_k127_7239417_17 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001953 291.0
HFD3_k127_7239417_18 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003139 294.0
HFD3_k127_7239417_19 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000002581 273.0
HFD3_k127_7239417_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003509 445.0
HFD3_k127_7239417_20 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000008109 224.0
HFD3_k127_7239417_21 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000001653 217.0
HFD3_k127_7239417_22 Glycosyl transferase family group 2 K07011 - - 0.00000000000000000000000000000000000000000000000001124 206.0
HFD3_k127_7239417_23 methyltransferase - - - 0.00000000000000000000000000000000000000000000000001886 191.0
HFD3_k127_7239417_24 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000001776 197.0
HFD3_k127_7239417_25 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000001416 168.0
HFD3_k127_7239417_26 Nucleotidyl transferase K00966 - 2.7.7.13 0.000000000000000000000000000000000000001923 167.0
HFD3_k127_7239417_27 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000436 165.0
HFD3_k127_7239417_28 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000002063 166.0
HFD3_k127_7239417_29 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000831 155.0
HFD3_k127_7239417_3 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 456.0
HFD3_k127_7239417_30 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000224 156.0
HFD3_k127_7239417_31 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000001017 141.0
HFD3_k127_7239417_32 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000003036 151.0
HFD3_k127_7239417_33 MraZ protein, putative antitoxin-like K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.0000000000000000000000000001618 120.0
HFD3_k127_7239417_34 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000001091 130.0
HFD3_k127_7239417_35 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000007215 105.0
HFD3_k127_7239417_36 PFAM ATP-binding region ATPase domain protein - - - 0.00000000000000001164 98.0
HFD3_k127_7239417_37 peptidyl-tyrosine sulfation - - - 0.00000000000000001301 97.0
HFD3_k127_7239417_38 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000002986 82.0
HFD3_k127_7239417_39 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000003369 91.0
HFD3_k127_7239417_4 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000725 435.0
HFD3_k127_7239417_40 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000005537 80.0
HFD3_k127_7239417_41 Hypothetical methyltransferase - - - 0.000000000002446 80.0
HFD3_k127_7239417_42 Cell division protein FtsQ K03589 - - 0.00000000001664 78.0
HFD3_k127_7239417_43 STAS domain - - - 0.0000006427 59.0
HFD3_k127_7239417_5 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051258,GO:0051301,GO:0065003,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 406.0
HFD3_k127_7239417_6 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 391.0
HFD3_k127_7239417_7 GHMP kinases C terminal K07031 - 2.7.1.168 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 368.0
HFD3_k127_7239417_8 Protein of unknown function (DUF2723) K16928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005687 377.0
HFD3_k127_7239417_9 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 360.0
HFD3_k127_7417409_0 PFAM BNR Asp-box repeat - - - 0.0 1280.0
HFD3_k127_7417409_1 Molybdopterin oxidoreductase K00123 - 1.17.1.9 2.921e-242 759.0
HFD3_k127_7417409_10 Ankyrin repeats (many copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 430.0
HFD3_k127_7417409_11 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 364.0
HFD3_k127_7417409_12 Pyridine nucleotide-disulphide oxidoreductase K07222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006724 353.0
HFD3_k127_7417409_13 3-demethylubiquinone-9 3-methyltransferase K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 291.0
HFD3_k127_7417409_14 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002191 262.0
HFD3_k127_7417409_15 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000004496 267.0
HFD3_k127_7417409_16 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004776 264.0
HFD3_k127_7417409_17 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006169 281.0
HFD3_k127_7417409_18 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000001034 278.0
HFD3_k127_7417409_19 Lamin Tail Domain K07004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001461 259.0
HFD3_k127_7417409_2 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00122,K00335 - 1.17.1.9,1.6.5.3 6.559e-211 700.0
HFD3_k127_7417409_20 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000000000000001696 263.0
HFD3_k127_7417409_21 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000000000000000000000000000000001155 230.0
HFD3_k127_7417409_22 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000004134 257.0
HFD3_k127_7417409_23 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000003096 222.0
HFD3_k127_7417409_24 molybdenum ion binding K07140 - - 0.0000000000000000000000000000000000000000000000000001429 201.0
HFD3_k127_7417409_25 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000000000000005338 177.0
HFD3_k127_7417409_26 Cation efflux family - - - 0.00000000000000000000000000000000000000000000002725 179.0
HFD3_k127_7417409_27 - - - - 0.0000000000000000000000000000000000000000000007252 177.0
HFD3_k127_7417409_28 Domain of unknown function (DUF4386) - - - 0.000000000000000000000000000000000000000048 167.0
HFD3_k127_7417409_29 DNA-templated transcription, initiation K02405 - - 0.000000000000000000000000000000000000002151 158.0
HFD3_k127_7417409_3 Involved in the tonB-independent uptake of proteins - - - 2.354e-210 681.0
HFD3_k127_7417409_30 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000001126 153.0
HFD3_k127_7417409_31 Molybdopterin oxidoreductase - - - 0.00000000000000000000000000000000002062 138.0
HFD3_k127_7417409_32 Cupin domain - - - 0.0000000000000000000000000000000002042 137.0
HFD3_k127_7417409_33 cellulose binding - - - 0.0000000000000000000000000000001144 141.0
HFD3_k127_7417409_34 DinB family - - - 0.0000000000000000000000008439 117.0
HFD3_k127_7417409_35 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000002815 78.0
HFD3_k127_7417409_36 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000006713 87.0
HFD3_k127_7417409_37 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000008316 86.0
HFD3_k127_7417409_39 transcriptional activator domain - - - 0.0000000000007247 80.0
HFD3_k127_7417409_4 Sodium/hydrogen exchanger family K03316 - - 8.494e-207 655.0
HFD3_k127_7417409_40 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000003479 70.0
HFD3_k127_7417409_41 Cupin domain - - - 0.0000000004425 72.0
HFD3_k127_7417409_42 metallopeptidase activity K01387,K01730,K20276 - 3.4.24.3,4.2.2.6 0.00000001258 68.0
HFD3_k127_7417409_43 - - - - 0.0000002704 56.0
HFD3_k127_7417409_44 Endonuclease Exonuclease Phosphatase - - - 0.00001102 60.0
HFD3_k127_7417409_5 Protein kinase domain K12132 - 2.7.11.1 5.403e-200 653.0
HFD3_k127_7417409_6 Tetratricopeptide repeat K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006123 565.0
HFD3_k127_7417409_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 471.0
HFD3_k127_7417409_8 cAMP biosynthetic process K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008651 503.0
HFD3_k127_7417409_9 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005568 460.0
HFD3_k127_7507874_0 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 564.0
HFD3_k127_7507874_1 COG0798 Arsenite efflux pump ACR3 and related K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009967 510.0
HFD3_k127_7507874_11 self proteolysis - - - 0.000000000000000006827 99.0
HFD3_k127_7507874_13 Dystroglycan-type cadherin-like domains. - - - 0.00000002463 66.0
HFD3_k127_7507874_14 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.00000008566 66.0
HFD3_k127_7507874_15 Belongs to the ompA family - - - 0.000474 54.0
HFD3_k127_7507874_2 regulation of microtubule-based process K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000559 417.0
HFD3_k127_7507874_3 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007239 337.0
HFD3_k127_7507874_4 OmpA family - - - 0.0000000000000000000000000000000000000000000000000000000000000001197 248.0
HFD3_k127_7507874_5 Haemolysin-III related K11068 - - 0.000000000000000000000000000000000000000000000000000000001857 211.0
HFD3_k127_7507874_6 - - - - 0.00000000000000000000000000000000000000000002342 168.0
HFD3_k127_7507874_7 Low molecular weight phosphatase family - - - 0.000000000000000000000000000000000000000001865 160.0
HFD3_k127_7507874_8 DNA-binding transcription factor activity K03892,K21903 - - 0.000000000000000000000000000000001395 136.0
HFD3_k127_7507874_9 DNA-binding protein VF530 - - - 0.00000000000000000007099 94.0
HFD3_k127_7546222_0 Ribosomal protein S1 K02945,K03527,K12132 GO:0005575,GO:0005576,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0065010 1.17.7.4,2.7.11.1 5.644e-221 711.0
HFD3_k127_7546222_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.398e-215 700.0
HFD3_k127_7546222_10 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000007824 143.0
HFD3_k127_7546222_11 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000009999 85.0
HFD3_k127_7546222_2 Methylenetetrahydrofolate reductase K00297,K00547,K00548 - 1.5.1.20,2.1.1.10,2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 615.0
HFD3_k127_7546222_3 aminopeptidase activity K07004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002748 302.0
HFD3_k127_7546222_4 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005077 298.0
HFD3_k127_7546222_5 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000003729 271.0
HFD3_k127_7546222_6 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - - 0.000000000000000000000000000000000000000000000000000000000000000002942 250.0
HFD3_k127_7546222_7 Belongs to the cytidylate kinase family. Type 1 subfamily K00800,K00945,K02945,K03527,K03977,K13799 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009240,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016491,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042380,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046490,GO:0046939,GO:0046940,GO:0048037,GO:0050145,GO:0051186,GO:0051188,GO:0051536,GO:0051538,GO:0051540,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.17.7.4,2.5.1.19,2.7.4.25,6.3.2.1 0.00000000000000000000000000000000000000000000000000003228 200.0
HFD3_k127_7546222_8 Belongs to the multicopper oxidase YfiH RL5 family K05810 GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0046983,GO:0055114 - 0.00000000000000000000000000000000000000000000000000102 192.0
HFD3_k127_7546222_9 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000002358 152.0
HFD3_k127_7613642_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 5.606e-227 732.0
HFD3_k127_7613642_1 Protein of unknown function (DUF2867) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 583.0
HFD3_k127_7613642_10 Mo-molybdopterin cofactor biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000002505 230.0
HFD3_k127_7613642_11 DoxX K15977 - - 0.00000000000000000000000000000000000000000006128 166.0
HFD3_k127_7613642_12 helix_turn_helix multiple antibiotic resistance protein K15973 - - 0.00000000000000000000000000000000002009 141.0
HFD3_k127_7613642_13 HNH endonuclease - - - 0.00000000000000000000000000000009829 138.0
HFD3_k127_7613642_14 Fibronectin-binding protein A N-terminus (FbpA) K01153,K15524 - 3.1.21.3,3.2.1.170 0.0000000000000000000000000002622 123.0
HFD3_k127_7613642_15 alpha-ribazole phosphatase activity K01834 - 5.4.2.11 0.000000000000000000000000000501 124.0
HFD3_k127_7613642_16 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000001392 102.0
HFD3_k127_7613642_17 Carboxypeptidase regulatory-like domain - - - 0.00000001297 68.0
HFD3_k127_7613642_19 Protein kinase domain K12132 - 2.7.11.1 0.0004021 47.0
HFD3_k127_7613642_2 WD40 repeats K20332 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 582.0
HFD3_k127_7613642_20 Protein conserved in bacteria - - - 0.0004692 53.0
HFD3_k127_7613642_3 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 542.0
HFD3_k127_7613642_4 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 464.0
HFD3_k127_7613642_5 lipid A export permease ATP-binding protein MsbA K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 402.0
HFD3_k127_7613642_6 OmpA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008711 331.0
HFD3_k127_7613642_7 Elongation factor SelB winged helix 3 K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001967 295.0
HFD3_k127_7613642_8 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000006981 265.0
HFD3_k127_7613642_9 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000005984 256.0
HFD3_k127_7632304_0 Nitrite reductase K00368,K08100 - 1.3.3.5,1.7.2.1 1.357e-211 668.0
HFD3_k127_7632304_1 Glucose sorbosone K21430 - - 8.725e-195 629.0
HFD3_k127_7632304_10 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.000000000151 70.0
HFD3_k127_7632304_11 peptidase activity, acting on L-amino acid peptides K01337,K20276 - 3.4.21.50 0.0000000012 72.0
HFD3_k127_7632304_12 energy transducer activity K00700,K03832 - 2.4.1.18 0.000000002045 70.0
HFD3_k127_7632304_13 metallopeptidase activity - - - 0.000000331 64.0
HFD3_k127_7632304_14 type 3a cellulose-binding domain protein - - - 0.00001429 59.0
HFD3_k127_7632304_15 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.00002003 53.0
HFD3_k127_7632304_16 Belongs to the peptidase S8 family - - - 0.00005353 55.0
HFD3_k127_7632304_17 ompA family - - - 0.00009676 55.0
HFD3_k127_7632304_2 Aldehyde dehydrogenase family K00128,K00135 - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 567.0
HFD3_k127_7632304_3 Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007776 475.0
HFD3_k127_7632304_4 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 346.0
HFD3_k127_7632304_5 CHAT domain - - - 0.00000000000000000000000000000000000000000000000000000000000002691 245.0
HFD3_k127_7632304_6 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.000000000000000000000007116 119.0
HFD3_k127_7632304_7 MotA/TolQ/ExbB proton channel family K03561 - - 0.0000000000000000000001225 106.0
HFD3_k127_7632304_8 Tetratricopeptide repeat - - - 0.00000000000000007454 94.0
HFD3_k127_7632304_9 Bacterial Ig-like domain (group 1) - - - 0.0000000000007942 83.0
HFD3_k127_7640377_0 Polysaccharide biosynthesis protein CapD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 515.0
HFD3_k127_7640377_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008379 390.0
HFD3_k127_7640377_10 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000000000002606 149.0
HFD3_k127_7640377_11 Glycosyltransferase like family 2 - - - 0.0000000000000000000000001401 124.0
HFD3_k127_7640377_12 Polysaccharide deacetylase - - - 0.000000000000000000000000606 123.0
HFD3_k127_7640377_13 -O-antigen K02847 - - 0.00000000000000000000006865 115.0
HFD3_k127_7640377_14 export protein K01991 - - 0.00000000000000000004821 102.0
HFD3_k127_7640377_15 ATP hydrolysis coupled proton transport - - - 0.000000000000000007876 93.0
HFD3_k127_7640377_2 amino acid activation for nonribosomal peptide biosynthetic process K17713,K20952 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004146 374.0
HFD3_k127_7640377_3 PFAM sugar transferase K13012 - - 0.000000000000000000000000000000000000000000000000000000000000001336 226.0
HFD3_k127_7640377_4 polysaccharide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000002235 211.0
HFD3_k127_7640377_5 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000001059 215.0
HFD3_k127_7640377_6 Glycosyl transferases group 1 K19424 - - 0.000000000000000000000000000000000000000000000000005928 207.0
HFD3_k127_7640377_7 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000001494 176.0
HFD3_k127_7640377_8 protein involved in exopolysaccharide biosynthesis K16554 - - 0.0000000000000000000000000000000000003839 162.0
HFD3_k127_7640377_9 glycosyl transferase family 2 K20444 - - 0.00000000000000000000000000000000000477 160.0
HFD3_k127_7665018_0 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 496.0
HFD3_k127_7665018_1 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 361.0
HFD3_k127_7665018_2 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 341.0
HFD3_k127_7665018_3 Domain of unknown function (DUF1998) K06877 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 334.0
HFD3_k127_7665018_4 lipase activity K15349 - - 0.00000000000000000000000000000000000003161 160.0
HFD3_k127_7665018_5 RNase_H superfamily K07502 - - 0.00000000000000000000000000000000002096 150.0
HFD3_k127_7665018_6 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.0000000000000000000000000000000006406 147.0
HFD3_k127_7665018_7 cold-shock protein K03704 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000306 106.0
HFD3_k127_792603_0 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 1.724e-219 699.0
HFD3_k127_792603_1 proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 583.0
HFD3_k127_792603_10 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000001426 252.0
HFD3_k127_792603_11 4-phosphoerythronate dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000007846 237.0
HFD3_k127_792603_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000266 177.0
HFD3_k127_792603_13 2 iron, 2 sulfur cluster binding K00334,K03943 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000001805 172.0
HFD3_k127_792603_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.3 0.000000000000000000000000000000000007249 140.0
HFD3_k127_792603_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000002714 125.0
HFD3_k127_792603_16 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000001062 128.0
HFD3_k127_792603_17 transcriptional regulators - - - 0.00000000000000000005616 97.0
HFD3_k127_792603_18 ABC transporter, transmembrane K18889 - - 0.000000000000000003367 98.0
HFD3_k127_792603_19 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000149 87.0
HFD3_k127_792603_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009905 517.0
HFD3_k127_792603_20 Transcriptional regulator - - - 0.000000202 61.0
HFD3_k127_792603_21 - K20326 - - 0.00000163 62.0
HFD3_k127_792603_3 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 522.0
HFD3_k127_792603_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 440.0
HFD3_k127_792603_5 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 460.0
HFD3_k127_792603_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 375.0
HFD3_k127_792603_7 electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 293.0
HFD3_k127_792603_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000001899 244.0
HFD3_k127_792603_9 electron transfer activity K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 - 0.00000000000000000000000000000000000000000000000000000000000000001467 242.0
HFD3_k127_827012_0 phosphoglycerate kinase activity K00927,K01803 GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3,5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 460.0
HFD3_k127_827012_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 432.0
HFD3_k127_827012_10 - - - - 0.00002079 59.0
HFD3_k127_827012_2 alpha beta alpha domain I K01840,K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 437.0
HFD3_k127_827012_3 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 392.0
HFD3_k127_827012_4 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005196 283.0
HFD3_k127_827012_5 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000002579 250.0
HFD3_k127_827012_6 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000002294 189.0
HFD3_k127_827012_7 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.00000000000000000000000000000000000000004599 168.0
HFD3_k127_827012_8 Peptidase M56 - - - 0.00000000000002021 86.0
HFD3_k127_827012_9 Preprotein translocase SecG subunit K03075 - - 0.000000000001237 73.0
HFD3_k127_827648_0 lysine biosynthetic process via aminoadipic acid - - - 2.219e-233 756.0
HFD3_k127_827648_1 RecQ zinc-binding K03654 - 3.6.4.12 6.014e-200 636.0
HFD3_k127_827648_10 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 354.0
HFD3_k127_827648_11 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 349.0
HFD3_k127_827648_12 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 357.0
HFD3_k127_827648_13 PFAM CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 326.0
HFD3_k127_827648_14 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 306.0
HFD3_k127_827648_15 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001389 297.0
HFD3_k127_827648_16 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006979 262.0
HFD3_k127_827648_17 protein F13E9.13, mitochondrial-like K06971 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001977 259.0
HFD3_k127_827648_18 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000004265 231.0
HFD3_k127_827648_19 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000643 233.0
HFD3_k127_827648_2 PFAM peptidase M13 K07386 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 596.0
HFD3_k127_827648_20 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000009833 209.0
HFD3_k127_827648_21 Belongs to the Dps family K04047 - - 0.000000000000000000000000000000000000000000000000004118 193.0
HFD3_k127_827648_22 GAF domain - - - 0.000000000000000000000000000000000000000000000004076 193.0
HFD3_k127_827648_23 4-hydroxybenzoate polyprenyltransferase K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000014 180.0
HFD3_k127_827648_24 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000007767 183.0
HFD3_k127_827648_25 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.0000000000000000000000000000000000000000000116 170.0
HFD3_k127_827648_26 PFAM EamA-like transporter family - - - 0.0000000000000000000000000000000003969 148.0
HFD3_k127_827648_27 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000002144 148.0
HFD3_k127_827648_28 Amidohydrolase family - - - 0.000000000000000000000000000000002701 131.0
HFD3_k127_827648_29 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for the ferulic acid decarboxylase FDC1. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000005566 147.0
HFD3_k127_827648_3 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004346 575.0
HFD3_k127_827648_30 ig-like, plexins, transcription factors - - - 0.00000000000000000000000000002642 138.0
HFD3_k127_827648_31 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000000000000542 128.0
HFD3_k127_827648_32 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000001961 97.0
HFD3_k127_827648_33 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.0000000000000000000002317 115.0
HFD3_k127_827648_34 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000007268 96.0
HFD3_k127_827648_35 Polymer-forming cytoskeletal - - - 0.00000000000000359 81.0
HFD3_k127_827648_36 PBS lyase HEAT-like repeat - - - 0.00000000000005714 86.0
HFD3_k127_827648_37 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.0000000000002136 82.0
HFD3_k127_827648_38 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000008659 75.0
HFD3_k127_827648_39 Galactose oxidase, central domain - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0005929,GO:0005930,GO:0031514,GO:0032838,GO:0042995,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044430,GO:0044441,GO:0044444,GO:0044446,GO:0044463,GO:0044464,GO:0097014,GO:0099568,GO:0120025,GO:0120038 - 0.00000000016 76.0
HFD3_k127_827648_4 COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 561.0
HFD3_k127_827648_40 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000001827 63.0
HFD3_k127_827648_41 Outer membrane protein beta-barrel domain - - - 0.0000000008232 67.0
HFD3_k127_827648_42 PFAM Single-stranded nucleic acid binding R3H K06346 - - 0.000000004143 69.0
HFD3_k127_827648_43 tail specific protease K03797 - 3.4.21.102 0.000000004976 68.0
HFD3_k127_827648_44 Transposase K07491 - - 0.00000001159 64.0
HFD3_k127_827648_45 Protein conserved in bacteria - - - 0.0000000184 66.0
HFD3_k127_827648_46 amine dehydrogenase activity - - - 0.00000007586 64.0
HFD3_k127_827648_47 cellulose binding - - - 0.000005562 61.0
HFD3_k127_827648_48 aspartic-type endopeptidase activity - - - 0.00003879 56.0
HFD3_k127_827648_49 Parallel beta-helix repeats - - - 0.000391 51.0
HFD3_k127_827648_5 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 407.0
HFD3_k127_827648_6 Mitochondrial biogenesis AIM24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 422.0
HFD3_k127_827648_7 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 408.0
HFD3_k127_827648_8 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 424.0
HFD3_k127_827648_9 secondary active sulfate transmembrane transporter activity K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 392.0
HFD3_k127_844269_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 459.0
HFD3_k127_844269_1 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009723 357.0
HFD3_k127_844269_2 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000088 211.0
HFD3_k127_844269_3 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000000273 103.0
HFD3_k127_844269_4 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.0000000000000000008443 102.0
HFD3_k127_844417_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009461 605.0
HFD3_k127_844417_1 Threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 350.0
HFD3_k127_844417_10 Putative Phosphatase K08966 - 3.1.3.87 0.00000000000000000000000000009381 133.0
HFD3_k127_844417_11 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16786,K16787 - - 0.000000000000000000000000001868 127.0
HFD3_k127_844417_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 315.0
HFD3_k127_844417_3 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 312.0
HFD3_k127_844417_4 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009539 312.0
HFD3_k127_844417_5 Putative neutral zinc metallopeptidase K06973 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001747 278.0
HFD3_k127_844417_6 (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000989 252.0
HFD3_k127_844417_7 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000001324 247.0
HFD3_k127_844417_8 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000001041 229.0
HFD3_k127_844417_9 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000767 138.0
HFD3_k127_958148_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K02887,K03628 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 1.981e-206 649.0
HFD3_k127_958148_1 cell adhesion involved in biofilm formation K13735 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 592.0
HFD3_k127_958148_10 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000000000000004734 197.0
HFD3_k127_958148_11 membrane - - - 0.0000000000000000000000000000000000000000000000000429 201.0
HFD3_k127_958148_12 endonuclease activity K07451 - - 0.0000000000000000000000000000000000000000000000005425 193.0
HFD3_k127_958148_13 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000004302 187.0
HFD3_k127_958148_14 nUDIX hydrolase - GO:0003674,GO:0003824,GO:0016787,GO:0016817,GO:0016818 - 0.000000000000000000000000000000000000000003504 175.0
HFD3_k127_958148_15 Domain of unknown function (DUF4150) - - - 0.000000000000000000000000000000000000001424 165.0
HFD3_k127_958148_16 Domains HisKA, HATPase_c - - - 0.000000000000000000000000000000000000006368 162.0
HFD3_k127_958148_17 synthase K00647 - 2.3.1.41 0.0000000000000000000000000000000000003687 154.0
HFD3_k127_958148_18 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000001381 158.0
HFD3_k127_958148_19 type VI secretion protein K11900 - - 0.000000000000000000000000000002748 138.0
HFD3_k127_958148_2 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008926 392.0
HFD3_k127_958148_20 Type VI secretion protein, EvpB/VC_A0108, tail sheath K11900 - - 0.00000000000000000000000009481 122.0
HFD3_k127_958148_21 Domain of unknown function DUF11 - - - 0.000000000000000000000002512 112.0
HFD3_k127_958148_22 Domain of unknown function (DU1801) - - - 0.0000000000000000000002758 101.0
HFD3_k127_958148_23 PFAM YbbR-like protein - - - 0.0000000001843 74.0
HFD3_k127_958148_24 - - - - 0.000000001443 67.0
HFD3_k127_958148_25 lyase activity - - - 0.000002726 56.0
HFD3_k127_958148_26 protein conserved in bacteria K11904 - - 0.000004207 59.0
HFD3_k127_958148_27 Sigma-70 region 2 K03088 - - 0.00002336 54.0
HFD3_k127_958148_28 TonB dependent receptor K02014 - - 0.00006063 57.0
HFD3_k127_958148_3 COG2513 PEP phosphonomutase and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 358.0
HFD3_k127_958148_4 fimbrial usher porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 348.0
HFD3_k127_958148_5 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004327 278.0
HFD3_k127_958148_6 Uncharacterized protein conserved in bacteria (DUF2169) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001891 262.0
HFD3_k127_958148_7 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000001234 248.0
HFD3_k127_958148_8 - - - - 0.00000000000000000000000000000000000000000000000000000004871 200.0
HFD3_k127_958148_9 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000002031 198.0