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Overview

ID MAG01692
Name HFD3_bin.34
Sample SMP0045
Taxonomy
Kingdom Bacteria
Phylum Actinomycetota
Class Acidimicrobiia
Order Acidimicrobiales
Family Ilumatobacteraceae
Genus JAENVT01
Species
Assembly information
Completeness (%) 95.01
Contamination (%) 2.77
GC content (%) 67.0
N50 (bp) 30,693
Genome size (bp) 4,302,823

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3896

Gene name Description KEGG GOs EC E-value Score Sequence
HFD3_k127_1002431_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000162 231.0
HFD3_k127_1002431_1 Bacterial protein of unknown function (DUF899) - - - 0.000000000000000000000000000000000000000000000000000000000008903 207.0
HFD3_k127_1011559_0 Transposase domain (DUF772) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 413.0
HFD3_k127_1060392_0 N-terminal domain of (some) glycogen debranching enzymes - - - 2.171e-271 854.0
HFD3_k127_1060392_1 Protein of unknown function (DUF1298) K00635 - 2.3.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006116 593.0
HFD3_k127_1060392_10 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000004448 154.0
HFD3_k127_1060392_11 Protein of unknown function (DUF3455) - - - 0.000000000000000000000000002649 121.0
HFD3_k127_1060392_12 branched-chain amino acid permease (azaleucine resistance) - - - 0.000000000000000000000000384 115.0
HFD3_k127_1060392_13 FtsX-like permease family - - - 0.0000000000000000002458 102.0
HFD3_k127_1060392_14 Domain of unknown function (DUF333) K09712 - - 0.0000000000000223 82.0
HFD3_k127_1060392_15 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000001214 72.0
HFD3_k127_1060392_2 Putative zinc binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 546.0
HFD3_k127_1060392_3 winged helix-turn-helix - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 537.0
HFD3_k127_1060392_4 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 523.0
HFD3_k127_1060392_5 ABC-2 type transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 503.0
HFD3_k127_1060392_6 cyclic nucleotide binding K15762 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 479.0
HFD3_k127_1060392_7 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 357.0
HFD3_k127_1060392_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000003705 230.0
HFD3_k127_1060392_9 Predicted membrane protein (DUF2231) - - - 0.000000000000000000000000000000000000000000000000000000000001124 216.0
HFD3_k127_106169_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003236 426.0
HFD3_k127_106169_1 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 298.0
HFD3_k127_106169_2 Putative peptidoglycan binding domain - - - 0.00000000000000000000000002089 126.0
HFD3_k127_106169_3 Peptidoglycan-binding domain 1 protein - - - 0.00000000000000000006891 104.0
HFD3_k127_106169_4 Cupredoxin-like domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.000000000000000004718 90.0
HFD3_k127_106169_5 - - - - 0.0000000002526 70.0
HFD3_k127_106169_6 - - - - 0.0000003428 63.0
HFD3_k127_1061827_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1417.0
HFD3_k127_1061827_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372,K02567 - - 0.0 1214.0
HFD3_k127_1061827_10 AMP-binding enzyme C-terminal domain K00666,K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006204 531.0
HFD3_k127_1061827_11 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004331 488.0
HFD3_k127_1061827_12 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 462.0
HFD3_k127_1061827_13 nitrite transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 438.0
HFD3_k127_1061827_14 DEAD DEAH box helicase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 445.0
HFD3_k127_1061827_15 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 420.0
HFD3_k127_1061827_16 synthase K00697,K16055 GO:0003674,GO:0003824,GO:0003825,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0030312,GO:0033554,GO:0034637,GO:0035251,GO:0040007,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046527,GO:0046872,GO:0046914,GO:0047260,GO:0050896,GO:0051716,GO:0070413,GO:0071704,GO:0071944,GO:1901576 2.4.1.15,2.4.1.347,3.1.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 436.0
HFD3_k127_1061827_17 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 423.0
HFD3_k127_1061827_18 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007986 397.0
HFD3_k127_1061827_19 Protein of unknown function (DUF1298) K00635 - 2.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 411.0
HFD3_k127_1061827_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.758e-319 984.0
HFD3_k127_1061827_20 NADH ubiquinone oxidoreductase, 20 Kd subunit K18007 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 386.0
HFD3_k127_1061827_21 ComEC Rec2-related protein K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 394.0
HFD3_k127_1061827_22 dna polymerase III delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007026 384.0
HFD3_k127_1061827_23 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 384.0
HFD3_k127_1061827_24 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 379.0
HFD3_k127_1061827_25 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005618 362.0
HFD3_k127_1061827_26 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 351.0
HFD3_k127_1061827_27 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 337.0
HFD3_k127_1061827_28 Oxidoreductase NAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 332.0
HFD3_k127_1061827_29 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007618 333.0
HFD3_k127_1061827_3 PFAM AMP-dependent synthetase and ligase K00666,K01909 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008922,GO:0009058,GO:0009987,GO:0015645,GO:0016020,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016874,GO:0016877,GO:0016878,GO:0017076,GO:0019752,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044464,GO:0046394,GO:0051704,GO:0070566,GO:0071704,GO:0071944,GO:0072330,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 6.2.1.20 2.884e-272 854.0
HFD3_k127_1061827_30 PAC2 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 320.0
HFD3_k127_1061827_31 Tetratricopeptide repeat K05838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 312.0
HFD3_k127_1061827_32 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 302.0
HFD3_k127_1061827_33 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000871 297.0
HFD3_k127_1061827_34 Short-chain dehydrogenase reductase sdr - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006733 280.0
HFD3_k127_1061827_35 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005327 278.0
HFD3_k127_1061827_36 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002602 274.0
HFD3_k127_1061827_37 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007422 274.0
HFD3_k127_1061827_38 Periplasmic binding protein domain K10543 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005975,GO:0005996,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0015749,GO:0015750,GO:0015753,GO:0019321,GO:0030246,GO:0030288,GO:0030313,GO:0031975,GO:0034219,GO:0036094,GO:0042597,GO:0042732,GO:0044238,GO:0044281,GO:0044464,GO:0048029,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704 - 0.00000000000000000000000000000000000000000000000000000000000000000000000002983 257.0
HFD3_k127_1061827_39 ABC-type branched-chain amino acid transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005077 267.0
HFD3_k127_1061827_4 MMPL family K07003 - - 6.72e-202 665.0
HFD3_k127_1061827_40 Protein of unknown function (DUF664) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007098 257.0
HFD3_k127_1061827_41 HPP family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003104 254.0
HFD3_k127_1061827_42 Fatty acid desaturase K00508 - 1.14.19.3 0.000000000000000000000000000000000000000000000000000000000000000000004673 247.0
HFD3_k127_1061827_43 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000001241 229.0
HFD3_k127_1061827_44 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.000000000000000000000000000000000000000000000000000000000000008688 227.0
HFD3_k127_1061827_45 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000001672 206.0
HFD3_k127_1061827_46 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000000000005384 207.0
HFD3_k127_1061827_47 oxidoreductase activity K07114 - - 0.00000000000000000000000000000000000000000000000000003011 206.0
HFD3_k127_1061827_48 lactoylglutathione lyase activity K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000889 192.0
HFD3_k127_1061827_49 Domain of unknown function (DUF1989) K09967 - - 0.00000000000000000000000000000000000000000000000001448 186.0
HFD3_k127_1061827_5 Glycogen debranching enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 621.0
HFD3_k127_1061827_50 ABC-type antimicrobial peptide transport system, ATPase component K02003,K05685 - - 0.0000000000000000000000000000000000000000000000202 178.0
HFD3_k127_1061827_51 Competence protein ComEA K02237 - - 0.0000000000000000000000000000000000000000000001256 177.0
HFD3_k127_1061827_52 Transcriptional regulator - - - 0.0000000000000000000000000000000000000003257 161.0
HFD3_k127_1061827_53 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.000000000000000000000000000000000000001786 158.0
HFD3_k127_1061827_54 Acetyltransferase (GNAT) family K00657 - 2.3.1.57 0.00000000000000000000000000000000000000339 151.0
HFD3_k127_1061827_55 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000004007 165.0
HFD3_k127_1061827_56 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000002699 151.0
HFD3_k127_1061827_57 cyclic nucleotide binding K10914 - - 0.0000000000000000000000000000000000004021 156.0
HFD3_k127_1061827_58 PFAM Glyoxalase Bleomycin resistance protein Dioxygenase superfamily K08234 - - 0.000000000000000000000000000000000006603 142.0
HFD3_k127_1061827_59 PFAM ABC transporter K02003 - - 0.00000000000000000000000000000007386 139.0
HFD3_k127_1061827_6 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008563 595.0
HFD3_k127_1061827_60 Hydrogenase maturation protease K03605 - - 0.00000000000000000000000006103 115.0
HFD3_k127_1061827_61 Cold shock protein K03704 - - 0.00000000000000000000000199 105.0
HFD3_k127_1061827_62 Major Facilitator Superfamily - - - 0.00000000000000000000005088 114.0
HFD3_k127_1061827_64 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000001715 84.0
HFD3_k127_1061827_66 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000003607 85.0
HFD3_k127_1061827_67 - - - - 0.00000000000008649 82.0
HFD3_k127_1061827_68 lipolytic protein G-D-S-L family - - - 0.00000000003239 74.0
HFD3_k127_1061827_69 Sucrose-6F-phosphate phosphohydrolase - - - 0.000001165 58.0
HFD3_k127_1061827_7 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 570.0
HFD3_k127_1061827_70 BFD-like [2Fe-2S] binding domain K02192 - - 0.0000166 49.0
HFD3_k127_1061827_71 - - - - 0.0004734 47.0
HFD3_k127_1061827_8 Rieske 2Fe-2S K00499 - 1.14.15.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 557.0
HFD3_k127_1061827_9 F420-dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 535.0
HFD3_k127_1062735_0 non-haem dioxygenase in morphine synthesis N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 472.0
HFD3_k127_1062735_1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004462 338.0
HFD3_k127_1062735_2 Virulence factor BrkB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001252 253.0
HFD3_k127_1062735_3 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000006186 145.0
HFD3_k127_1062735_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000018 104.0
HFD3_k127_1062735_5 ROK family K00845 - 2.7.1.2 0.000000000000000000003403 96.0
HFD3_k127_106808_0 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000008714 215.0
HFD3_k127_106808_1 Glycosyltransferase like family 2 K20444 - - 0.000000000000000000002276 97.0
HFD3_k127_1086714_0 indolepyruvate ferredoxin oxidoreductase K00179,K04090 - 1.2.7.8 1.976e-309 984.0
HFD3_k127_1086714_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 4.274e-299 942.0
HFD3_k127_1086714_10 4-hydroxybenzoate K00481 - 1.14.13.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 505.0
HFD3_k127_1086714_11 Protein synonym acyl-CoA synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 503.0
HFD3_k127_1086714_12 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 431.0
HFD3_k127_1086714_13 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000868 394.0
HFD3_k127_1086714_14 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 371.0
HFD3_k127_1086714_15 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 347.0
HFD3_k127_1086714_16 Periplasmic binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009079 348.0
HFD3_k127_1086714_17 protocatechuate 3,4-dioxygenase activity K00449 - 1.13.11.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005776 326.0
HFD3_k127_1086714_18 ANTAR K22010 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 303.0
HFD3_k127_1086714_19 methyltransferase K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001343 300.0
HFD3_k127_1086714_2 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K03520 - 1.2.5.3 3.433e-220 708.0
HFD3_k127_1086714_20 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000002473 243.0
HFD3_k127_1086714_21 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K07684 - - 0.000000000000000000000000000000000000000000000000000000000000004046 222.0
HFD3_k127_1086714_22 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000005225 219.0
HFD3_k127_1086714_23 - - - - 0.0000000000000000000000000000000000000000000000000000000000001033 229.0
HFD3_k127_1086714_24 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000008711 217.0
HFD3_k127_1086714_25 3-oxoadipate enol-lactonase K01055 - 3.1.1.24 0.000000000000000000000000000000000000000000000000000000000004697 223.0
HFD3_k127_1086714_26 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000003459 216.0
HFD3_k127_1086714_27 Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant K06720 - 4.2.1.108 0.00000000000000000000000000000000000000000000000000000000124 202.0
HFD3_k127_1086714_28 FabA-like domain K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000003048 205.0
HFD3_k127_1086714_29 endonuclease activity - - - 0.0000000000000000000000000000000000000000000000000000007522 214.0
HFD3_k127_1086714_3 Ribosomal protein S1-like RNA-binding domain K02945 - - 3.044e-219 688.0
HFD3_k127_1086714_30 Dioxygenase K00448 - 1.13.11.3 0.0000000000000000000000000000000000000000000000000002587 198.0
HFD3_k127_1086714_31 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000003658 192.0
HFD3_k127_1086714_32 oxidation-reduction process K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000000004594 184.0
HFD3_k127_1086714_33 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000005737 200.0
HFD3_k127_1086714_34 phosphorelay sensor kinase activity K03406,K07673,K07675 - 2.7.13.3 0.0000000000000000000000000000000000000000000004482 189.0
HFD3_k127_1086714_35 Transcriptional regulator - - - 0.00000000000000000000000000000000000000005044 163.0
HFD3_k127_1086714_36 Lyase K01857 - 5.5.1.2 0.0000000000000000000000000000000000000001726 163.0
HFD3_k127_1086714_37 Acetyltransferase (GNAT) domain K00663,K03790 - 2.3.1.128,2.3.1.82 0.00000000000000000000000000000000002158 142.0
HFD3_k127_1086714_38 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000005211 139.0
HFD3_k127_1086714_39 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000003777 118.0
HFD3_k127_1086714_4 4-hydroxyphenylacetate 3-monooxygenase oxygenase K00483 - 1.14.14.9 1.165e-216 685.0
HFD3_k127_1086714_40 Protein of unknown function (DUF1810) - - - 0.0000000000000000000000000003827 120.0
HFD3_k127_1086714_41 fatty acid desaturase transmembrane protein - - - 0.000000000000000000000003636 117.0
HFD3_k127_1086714_42 - - - - 0.000000000000000001188 89.0
HFD3_k127_1086714_43 Alpha/beta hydrolase family - - - 0.000000000000004876 85.0
HFD3_k127_1086714_45 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000004591 56.0
HFD3_k127_1086714_5 Acyl transferase domain K00645 - 2.3.1.39 4.37e-198 622.0
HFD3_k127_1086714_6 COGs COG0620 Methionine synthase II (cobalamin-independent) K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 543.0
HFD3_k127_1086714_7 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 524.0
HFD3_k127_1086714_8 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 529.0
HFD3_k127_1086714_9 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004922 505.0
HFD3_k127_1106359_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0 1137.0
HFD3_k127_1106359_1 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 557.0
HFD3_k127_1106359_10 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000461 255.0
HFD3_k127_1106359_11 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006388 254.0
HFD3_k127_1106359_12 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000002492 248.0
HFD3_k127_1106359_13 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000007119 248.0
HFD3_k127_1106359_14 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000003385 212.0
HFD3_k127_1106359_15 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000006258 192.0
HFD3_k127_1106359_16 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000827 192.0
HFD3_k127_1106359_17 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000004969 153.0
HFD3_k127_1106359_18 - - - - 0.0000000000000000000000006394 106.0
HFD3_k127_1106359_19 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000004869 109.0
HFD3_k127_1106359_2 Belongs to the ABC transporter superfamily K02031,K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 460.0
HFD3_k127_1106359_20 PFAM luciferase-like K00320 - 1.5.98.2 0.0000000000000000000000858 111.0
HFD3_k127_1106359_21 ABC transporter K02049 - - 0.000000000000000000000123 98.0
HFD3_k127_1106359_22 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000007926 105.0
HFD3_k127_1106359_3 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005316 452.0
HFD3_k127_1106359_4 Creatininase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006533 349.0
HFD3_k127_1106359_5 Xanthine dehydrogenase iron-sulfur cluster and FAD-binding subunit A K13481 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 326.0
HFD3_k127_1106359_6 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 315.0
HFD3_k127_1106359_7 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000749 307.0
HFD3_k127_1106359_8 PFAM Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006224 290.0
HFD3_k127_1106359_9 phosphoribosyltransferase K07101 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000627 283.0
HFD3_k127_1117304_0 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000512 414.0
HFD3_k127_11189_0 Cell division protein FtsA K03569 - - 9.196e-195 609.0
HFD3_k127_11189_1 RNB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005884 516.0
HFD3_k127_11189_2 Pfam:Zinicin_2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 452.0
HFD3_k127_11189_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 344.0
HFD3_k127_11189_4 Epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 340.0
HFD3_k127_11189_5 Transcriptional regulatory protein, C terminal K07776 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001873 253.0
HFD3_k127_11189_6 MoaE protein K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000000000009818 232.0
HFD3_k127_11189_7 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000218 78.0
HFD3_k127_11189_8 Peptidase s1 and s6 chymotrypsin hap K08372 - - 0.0000003403 62.0
HFD3_k127_1135781_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 4.502e-274 859.0
HFD3_k127_1135781_1 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008976 381.0
HFD3_k127_1135781_2 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000007188 246.0
HFD3_k127_1135781_3 protein secretion K20276,K21449 - - 0.00000000000000000000000000000000000000000000000000000005618 214.0
HFD3_k127_1135781_5 - - - - 0.0000957 46.0
HFD3_k127_1140931_0 Major facilitator Superfamily - - - 5.748e-282 885.0
HFD3_k127_1140931_1 AMP-binding enzyme K00666,K01897 - 6.2.1.3 1.495e-238 756.0
HFD3_k127_1140931_10 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000003678 139.0
HFD3_k127_1140931_11 TIR domain - - - 0.00000000000000000000000000005008 133.0
HFD3_k127_1140931_2 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009423 337.0
HFD3_k127_1140931_3 COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 330.0
HFD3_k127_1140931_4 carboxylic acid catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 305.0
HFD3_k127_1140931_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 313.0
HFD3_k127_1140931_6 lipid binding K14954,K14955 GO:0003674,GO:0005102,GO:0005488,GO:0005515,GO:0005543,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008289,GO:0009405,GO:0009605,GO:0009607,GO:0009966,GO:0010469,GO:0010646,GO:0016020,GO:0020012,GO:0023051,GO:0030312,GO:0030545,GO:0030682,GO:0031982,GO:0035091,GO:0042783,GO:0042785,GO:0043167,GO:0043168,GO:0043207,GO:0043226,GO:0043227,GO:0043230,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044421,GO:0044464,GO:0048018,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051812,GO:0051832,GO:0051834,GO:0051861,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0065009,GO:0071944,GO:0075136,GO:0097367,GO:0097691,GO:0098772,GO:1903561 - 0.00000000000000000000000000000000000000000000000000000000000000000002929 241.0
HFD3_k127_1140931_7 CHAT domain - - - 0.00000000000000000000000000000000000000000000000000000000000793 238.0
HFD3_k127_1140931_8 competence protein COMEC - - - 0.0000000000000000000000000000000000000006731 173.0
HFD3_k127_1140931_9 ABC-2 family transporter protein - - - 0.000000000000000000000000000000000003755 147.0
HFD3_k127_1148761_0 Class-II DAHP synthetase family K01626 - 2.5.1.54 7.457e-232 725.0
HFD3_k127_1148761_1 ABC transporter transmembrane region K06147 - - 2.057e-205 663.0
HFD3_k127_1148761_10 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 319.0
HFD3_k127_1148761_11 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 321.0
HFD3_k127_1148761_12 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008941 310.0
HFD3_k127_1148761_13 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 300.0
HFD3_k127_1148761_14 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 305.0
HFD3_k127_1148761_15 Acetyltransferase (isoleucine patch K00661 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 2.3.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 293.0
HFD3_k127_1148761_16 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 292.0
HFD3_k127_1148761_17 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 285.0
HFD3_k127_1148761_18 alpha-ribazole phosphatase activity K02226,K15634 - 3.1.3.73,5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 284.0
HFD3_k127_1148761_19 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000000000000000001454 258.0
HFD3_k127_1148761_2 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 570.0
HFD3_k127_1148761_20 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002338 247.0
HFD3_k127_1148761_21 Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP K01004 GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050520,GO:0071704,GO:0090407,GO:1901576 2.7.8.24 0.00000000000000000000000000000000000000000000009031 178.0
HFD3_k127_1148761_22 5-methyl-5,6,7,8-tetrahydromethanopterin-dependent methyltransferase activity - - - 0.00000000000000000000000000000000000000000002346 170.0
HFD3_k127_1148761_23 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000005165 168.0
HFD3_k127_1148761_25 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000001564 141.0
HFD3_k127_1148761_26 response to heat K07090 - - 0.000000000000000000000000000000007562 140.0
HFD3_k127_1148761_28 YhhN family - - - 0.000000000000000000000000001788 119.0
HFD3_k127_1148761_3 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 557.0
HFD3_k127_1148761_30 Domain of unknown function (DUF4352) - - - 0.00007471 53.0
HFD3_k127_1148761_4 ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 557.0
HFD3_k127_1148761_5 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 522.0
HFD3_k127_1148761_6 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 466.0
HFD3_k127_1148761_7 Peptidase M1, membrane alanine aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 409.0
HFD3_k127_1148761_8 PFAM Metallo-beta-lactamase superfamily - GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006090,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019184,GO:0019752,GO:0031974,GO:0032787,GO:0034641,GO:0042398,GO:0043043,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0051186,GO:0051188,GO:0070013,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 335.0
HFD3_k127_1148761_9 PFAM Peptidase family S58 K18572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 333.0
HFD3_k127_115455_0 Aldehyde dehydrogenase K04072,K15515 - 1.1.1.1,1.2.1.10,1.2.1.81 9.139e-267 834.0
HFD3_k127_115455_1 Squalene-hopene cyclase N-terminal domain K06045 - 4.2.1.129,5.4.99.17 2.988e-264 828.0
HFD3_k127_115455_10 Predicted Permease Membrane Region K07085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 337.0
HFD3_k127_115455_11 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 303.0
HFD3_k127_115455_12 Threonyl alanyl tRNA synthetase SAD K07050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006645 295.0
HFD3_k127_115455_13 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007821 303.0
HFD3_k127_115455_14 phytoene synthase K02291 GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0016767,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001657 278.0
HFD3_k127_115455_15 Squalene phytoene synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003342 263.0
HFD3_k127_115455_16 Permeases of the drug metabolite transporter DMT superfamily K15269 - - 0.00000000000000000000000000000000000000000000000000000000000000000001985 252.0
HFD3_k127_115455_17 Aminoglycoside 2'-N-acetyltransferase K17840 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008080,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016020,GO:0016137,GO:0016139,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016999,GO:0017001,GO:0017144,GO:0030647,GO:0030649,GO:0034069,GO:0044237,GO:0044248,GO:0044464,GO:0047921,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901575,GO:1901657,GO:1901658 2.3.1.59 0.000000000000000000000000000000000000000000000000000000000006035 218.0
HFD3_k127_115455_18 PAP2 superfamily - - - 0.0000000000000000000000000000000000000000000000000000000009191 211.0
HFD3_k127_115455_19 molybdopterin cofactor binding - - - 0.000000000000000000000000000000000000000000000000000000008223 208.0
HFD3_k127_115455_2 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004557 563.0
HFD3_k127_115455_20 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000001408 201.0
HFD3_k127_115455_21 EVE domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000002582 194.0
HFD3_k127_115455_22 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000007439 174.0
HFD3_k127_115455_23 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000002378 165.0
HFD3_k127_115455_24 YCII-related domain - - - 0.00000000000000000000000000000000000000001267 162.0
HFD3_k127_115455_25 KR domain K07124 - - 0.00000000000000000000000000000000000004992 158.0
HFD3_k127_115455_26 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000002677 147.0
HFD3_k127_115455_27 - - - - 0.0000000000000000000000000000000000006451 144.0
HFD3_k127_115455_28 Peptidoglycan-binding domain 1 protein K07260,K21449 - 3.4.17.14 0.0000000000000000000000000000000000198 154.0
HFD3_k127_115455_29 ATP-grasp domain - - - 0.0000000000000000003411 102.0
HFD3_k127_115455_3 Glycosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 563.0
HFD3_k127_115455_30 Belongs to the 'phage' integrase family - - - 0.0000000000000000003598 98.0
HFD3_k127_115455_31 - - - - 0.0000000000942 70.0
HFD3_k127_115455_32 Bacterial regulatory proteins, tetR family - - - 0.0000001829 62.0
HFD3_k127_115455_33 Phosphatase - - - 0.0000402 49.0
HFD3_k127_115455_34 transcriptional regulator - - - 0.0001887 52.0
HFD3_k127_115455_36 DsrE/DsrF-like family - - - 0.000355 46.0
HFD3_k127_115455_4 PFAM sigma-70 region 2 domain protein K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 514.0
HFD3_k127_115455_5 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 489.0
HFD3_k127_115455_6 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004546 446.0
HFD3_k127_115455_7 squalene-associated FAD-dependent desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005458 436.0
HFD3_k127_115455_8 Taurine catabolism dioxygenase TauD, TfdA family K22303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 401.0
HFD3_k127_115455_9 PFAM glycosidase, PH1107-related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 397.0
HFD3_k127_1167117_0 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007487 499.0
HFD3_k127_1167117_10 Protein conserved in bacteria - - - 0.00000002972 66.0
HFD3_k127_1167117_11 TIGRFAM Outer membrane protein - - - 0.0000001336 64.0
HFD3_k127_1167117_2 Domain of unknown function (DUF4389) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 430.0
HFD3_k127_1167117_3 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000901 396.0
HFD3_k127_1167117_4 Belongs to the ATCase OTCase family - GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0019627,GO:0034641,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 334.0
HFD3_k127_1167117_5 Domain present in PSD-95, Dlg, and ZO-1/2. K08372 - - 0.000000000000000000000000000000000000000000000000000000000000000000001274 259.0
HFD3_k127_1167117_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000003113 232.0
HFD3_k127_1167117_7 precorrin-8X methylmutase activity K06042 - 5.4.99.60,5.4.99.61 0.0000000000000000000000000000000000000000000000000000000006901 211.0
HFD3_k127_1167117_8 belongs to the sigma-70 factor family, ECF subfamily - - - 0.0000000000000000000000000133 118.0
HFD3_k127_1182920_0 Glutamine amidotransferase domain K00820 - 2.6.1.16 0.0 1399.0
HFD3_k127_1182920_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000064 627.0
HFD3_k127_1182920_10 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 400.0
HFD3_k127_1182920_11 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 389.0
HFD3_k127_1182920_12 ABC transporter K06147,K06148 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 396.0
HFD3_k127_1182920_13 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 390.0
HFD3_k127_1182920_14 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005058 375.0
HFD3_k127_1182920_15 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 361.0
HFD3_k127_1182920_16 PFAM Glycosyl transferases group 1 K03867 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 361.0
HFD3_k127_1182920_17 ABC transporter transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 367.0
HFD3_k127_1182920_18 CYTH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004434 367.0
HFD3_k127_1182920_19 tRNA threonylcarbamoyladenosine modification K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005967 327.0
HFD3_k127_1182920_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 606.0
HFD3_k127_1182920_20 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 319.0
HFD3_k127_1182920_21 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 295.0
HFD3_k127_1182920_22 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004295 280.0
HFD3_k127_1182920_23 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001058 278.0
HFD3_k127_1182920_24 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003917 271.0
HFD3_k127_1182920_25 Metallopeptidase family M24 K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000001024 267.0
HFD3_k127_1182920_26 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001297 254.0
HFD3_k127_1182920_27 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000005748 244.0
HFD3_k127_1182920_28 Phosphoribosyl transferase domain K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000003278 233.0
HFD3_k127_1182920_29 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000000000000000000000000000003305 230.0
HFD3_k127_1182920_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 526.0
HFD3_k127_1182920_30 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000000000000000000000000000000000000000000106 238.0
HFD3_k127_1182920_31 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000000001175 223.0
HFD3_k127_1182920_32 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000000000000003821 212.0
HFD3_k127_1182920_33 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000001749 212.0
HFD3_k127_1182920_34 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.000000000000000000000000000000000000000000000000000000008223 208.0
HFD3_k127_1182920_35 binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000000000000000006073 200.0
HFD3_k127_1182920_36 Ribosomal protein L17 K02879 - - 0.00000000000000000000000000000000000000000000000001762 182.0
HFD3_k127_1182920_37 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000000000000000002307 176.0
HFD3_k127_1182920_38 Ribosomal protein S9/S16 K02996 - - 0.00000000000000000000000000000000000000000000000287 177.0
HFD3_k127_1182920_39 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000000000000000002277 172.0
HFD3_k127_1182920_4 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - GO:0008150,GO:0010565,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0080090 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 520.0
HFD3_k127_1182920_40 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000005792 172.0
HFD3_k127_1182920_41 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000000000112 167.0
HFD3_k127_1182920_42 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000000001641 145.0
HFD3_k127_1182920_43 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000000000000000000004496 141.0
HFD3_k127_1182920_44 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000001093 146.0
HFD3_k127_1182920_45 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.00000000000000000000000000000000306 130.0
HFD3_k127_1182920_46 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000001604 125.0
HFD3_k127_1182920_47 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000000000000001069 115.0
HFD3_k127_1182920_48 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000002069 113.0
HFD3_k127_1182920_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 500.0
HFD3_k127_1182920_50 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000002296 90.0
HFD3_k127_1182920_51 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000004927 74.0
HFD3_k127_1182920_52 Ribosomal protein L30p/L7e K02907 - - 0.00000000000002274 81.0
HFD3_k127_1182920_53 Forms part of the polypeptide exit tunnel K02926 - - 0.000001469 53.0
HFD3_k127_1182920_6 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008216 483.0
HFD3_k127_1182920_7 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005264 470.0
HFD3_k127_1182920_8 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 461.0
HFD3_k127_1182920_9 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 400.0
HFD3_k127_1208248_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005048 552.0
HFD3_k127_1208248_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771 427.0
HFD3_k127_1208248_10 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000000000000000005039 108.0
HFD3_k127_1208248_11 AzlC protein - - - 0.00000000000000004459 90.0
HFD3_k127_1208248_2 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 381.0
HFD3_k127_1208248_3 FAD binding domain K21401 - 1.3.99.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006501 372.0
HFD3_k127_1208248_4 redox protein regulator of disulfide bond formation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009454 277.0
HFD3_k127_1208248_5 FtsX-like permease family K02004 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000853 243.0
HFD3_k127_1208248_6 Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000001391 204.0
HFD3_k127_1208248_7 Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000001283 205.0
HFD3_k127_1208248_8 A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics - - - 0.000000000000000000000000000000000000000000000000008865 190.0
HFD3_k127_1208248_9 transcriptional regulator - - - 0.000000000000000000000000000000000000001832 154.0
HFD3_k127_1231172_0 Serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000004529 239.0
HFD3_k127_1231172_1 DNA-binding transcriptional activator of the SARP family - - - 0.0000000000000000000000000000000000000000000000000002288 207.0
HFD3_k127_1263523_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 605.0
HFD3_k127_1263523_1 ABC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 590.0
HFD3_k127_1263523_10 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006749 354.0
HFD3_k127_1263523_12 PFAM binding-protein-dependent transport systems inner membrane component K05814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 349.0
HFD3_k127_1263523_13 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 336.0
HFD3_k127_1263523_14 Carbohydrate ABC transporter ATP-binding protein, CUT1 family K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007116 330.0
HFD3_k127_1263523_15 L-asparaginase II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 318.0
HFD3_k127_1263523_16 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001356 280.0
HFD3_k127_1263523_17 Binding-protein-dependent transport systems inner membrane component K02026,K05815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009142 276.0
HFD3_k127_1263523_18 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000001576 260.0
HFD3_k127_1263523_19 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000008662 190.0
HFD3_k127_1263523_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006413 557.0
HFD3_k127_1263523_20 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000003822 182.0
HFD3_k127_1263523_21 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000002113 165.0
HFD3_k127_1263523_22 - - - - 0.000000000000000000000000000000000000000002097 168.0
HFD3_k127_1263523_23 Antibiotic biosynthesis monooxygenase K06996,K21481 - 1.14.99.57 0.0000000000000000000000000000000000000000446 154.0
HFD3_k127_1263523_25 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000001437 121.0
HFD3_k127_1263523_26 dehydratase K18122 - - 0.00000000000000000001094 102.0
HFD3_k127_1263523_28 Integrase core domain - - - 0.00002288 53.0
HFD3_k127_1263523_3 Transposase K07493 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 561.0
HFD3_k127_1263523_4 KaiC K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 549.0
HFD3_k127_1263523_5 protein conserved in bacteria K09927 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006361 448.0
HFD3_k127_1263523_6 permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009057 440.0
HFD3_k127_1263523_7 DisA bacterial checkpoint controller linker region K07067 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 412.0
HFD3_k127_1263523_8 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 414.0
HFD3_k127_1263523_9 carbohydrate transport K05813 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 387.0
HFD3_k127_1267_0 SNF2 family N-terminal domain - - - 0.0 1187.0
HFD3_k127_1267_1 UDP binding domain K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007501 531.0
HFD3_k127_1267_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000001088 167.0
HFD3_k127_1267_3 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000143 153.0
HFD3_k127_1267_4 Methyltransferase domain - - - 0.0000000000000000000000000000000002651 139.0
HFD3_k127_1267_5 Domain of unknown function (DUF4389) - - - 0.000000000000000000000000001509 121.0
HFD3_k127_1267_6 acetyltransferase - - - 0.0000000000000000000000883 108.0
HFD3_k127_1302601_0 hydrolase, family 65, central catalytic K05342 - 2.4.1.64 9.896e-256 812.0
HFD3_k127_1302601_1 hydrolase, family 65, central catalytic K10231 - 2.4.1.230 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 532.0
HFD3_k127_1302601_2 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005791 286.0
HFD3_k127_1302601_3 transcriptional regulator K10947 - - 0.0000000000000000000000000065 114.0
HFD3_k127_130638_0 aldo keto reductase K19265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 555.0
HFD3_k127_130638_1 SnoaL-like domain - - - 0.000000000000000000000000000000001567 134.0
HFD3_k127_130638_2 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 0.0000000000000000000000003727 104.0
HFD3_k127_131949_0 Transketolase, pyrimidine binding domain K21417 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 510.0
HFD3_k127_131949_1 PFAM Dehydrogenase, E1 component K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000813 465.0
HFD3_k127_131949_2 Putative serine esterase (DUF676) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 353.0
HFD3_k127_131949_3 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001017 261.0
HFD3_k127_131949_4 ATP-NAD kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002723 249.0
HFD3_k127_131949_5 Domain of unknown function (DUF4188) - - - 0.00000000000000000000000000000000000000000000000000000000000000000005032 238.0
HFD3_k127_131949_6 NIPSNAP - - - 0.000000000000000000000000000000000000000000000000001503 193.0
HFD3_k127_131949_7 PFAM Biotin lipoyl attachment - - - 0.0000000000000000000008003 100.0
HFD3_k127_131949_8 galactose oxidase - - - 0.0000000000000000008752 96.0
HFD3_k127_131949_9 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000004798 87.0
HFD3_k127_1330255_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 1.146e-245 786.0
HFD3_k127_1330255_1 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 1.558e-236 741.0
HFD3_k127_1330255_10 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000000000002203 177.0
HFD3_k127_1330255_11 Domain of unknown function (DUF4202) - - - 0.000000000000000000000000000000000000002501 158.0
HFD3_k127_1330255_12 FR47-like protein - - - 0.000000000000000000001212 101.0
HFD3_k127_1330255_13 - - - - 0.0000000000000002049 88.0
HFD3_k127_1330255_2 Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000639 585.0
HFD3_k127_1330255_3 Belongs to the argininosuccinate synthase family. Type K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 537.0
HFD3_k127_1330255_4 Nitrite and sulphite reductase 4Fe-4S domain K00362,K00366,K00381,K00392 - 1.7.1.15,1.7.7.1,1.8.1.2,1.8.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 448.0
HFD3_k127_1330255_5 peptidase K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 422.0
HFD3_k127_1330255_6 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005035 340.0
HFD3_k127_1330255_7 Helix-turn-helix domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 331.0
HFD3_k127_1330255_8 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 314.0
HFD3_k127_1330255_9 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000001471 206.0
HFD3_k127_133681_0 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005393 362.0
HFD3_k127_133681_1 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 406.0
HFD3_k127_133681_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000129 190.0
HFD3_k127_133681_3 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000007294 139.0
HFD3_k127_133681_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000004125 138.0
HFD3_k127_133681_5 FtsX-like permease family - - - 0.0000000000000002218 90.0
HFD3_k127_133681_6 Periplasmic component of the Tol biopolymer transport system - - - 0.0000006707 57.0
HFD3_k127_137257_0 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 0.0 1163.0
HFD3_k127_137257_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 - 2.615e-233 736.0
HFD3_k127_137257_10 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000001414 201.0
HFD3_k127_137257_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000003342 169.0
HFD3_k127_137257_12 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000001604 149.0
HFD3_k127_137257_14 Protein of unknown function (DUF983) - - - 0.00000000000000000000004701 103.0
HFD3_k127_137257_15 helix_turn_helix, mercury resistance - - - 0.000000000000000000002507 98.0
HFD3_k127_137257_2 ABC transporter K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 498.0
HFD3_k127_137257_3 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 441.0
HFD3_k127_137257_4 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 452.0
HFD3_k127_137257_5 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005548 447.0
HFD3_k127_137257_6 PFAM monooxygenase FAD-binding K05712 - 1.14.13.127 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 437.0
HFD3_k127_137257_7 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441 377.0
HFD3_k127_137257_8 DeoR C terminal sensor domain K03436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 307.0
HFD3_k127_137257_9 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000003758 236.0
HFD3_k127_1393910_0 - - - - 0.00000001151 66.0
HFD3_k127_1472138_0 Oligopeptidase F K08602 - - 5.654e-244 773.0
HFD3_k127_1472138_1 PFAM Endonuclease Exonuclease phosphatase K07004 - - 2.837e-208 673.0
HFD3_k127_1472138_10 acetyltransferase - - - 0.00000000000000000004278 99.0
HFD3_k127_1472138_11 Belongs to the peptidase S26 family K13280 - 3.4.21.89 0.00000001496 68.0
HFD3_k127_1472138_12 - - - - 0.000004362 57.0
HFD3_k127_1472138_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 621.0
HFD3_k127_1472138_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 509.0
HFD3_k127_1472138_4 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 324.0
HFD3_k127_1472138_5 heme binding K06401,K21472 - - 0.000000000000000000000000000000000000000000000000000000000000000005724 245.0
HFD3_k127_1472138_6 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000001048 171.0
HFD3_k127_1472138_7 Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol K15520 - 2.3.1.189 0.000000000000000000000000000000000000000000582 159.0
HFD3_k127_1472138_8 - - - - 0.0000000000000000000000000000008376 131.0
HFD3_k127_1556812_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1410.0
HFD3_k127_1556812_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 6.405e-247 774.0
HFD3_k127_1556812_10 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 385.0
HFD3_k127_1556812_11 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 312.0
HFD3_k127_1556812_12 Histidine biosynthesis protein K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 305.0
HFD3_k127_1556812_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005923 282.0
HFD3_k127_1556812_14 Mitochondrial biogenesis AIM24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001383 269.0
HFD3_k127_1556812_15 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002226 267.0
HFD3_k127_1556812_16 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000001026 257.0
HFD3_k127_1556812_17 Protein of unknown function (DUF664) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006781 254.0
HFD3_k127_1556812_18 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009101 261.0
HFD3_k127_1556812_19 Aminomethyltransferase folate-binding domain K06980 - - 0.0000000000000000000000000000000000000000000000000000000000002439 222.0
HFD3_k127_1556812_2 Anthranilate synthase component I, N terminal region K01657 - 4.1.3.27 1.253e-241 756.0
HFD3_k127_1556812_20 dioxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000008675 207.0
HFD3_k127_1556812_21 Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol K15520 - 2.3.1.189 0.0000000000000000000000000000000000000000000000000000009449 199.0
HFD3_k127_1556812_22 inositol monophosphate 1-phosphatase activity K01082,K01092 - 3.1.3.25,3.1.3.7 0.00000000000000000000000000000000000000000000000000006131 195.0
HFD3_k127_1556812_23 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.000000000000000000000000000000000000000000000001164 176.0
HFD3_k127_1556812_24 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000000003417 158.0
HFD3_k127_1556812_25 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000005161 132.0
HFD3_k127_1556812_26 PFAM AIG2 family protein - - - 0.0000000000000000000000000000001486 138.0
HFD3_k127_1556812_28 Domain of unknown function (DUF4129) - - - 0.0000000000000000000000004694 113.0
HFD3_k127_1556812_29 YjbR - - - 0.0000000000000004014 85.0
HFD3_k127_1556812_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 514.0
HFD3_k127_1556812_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 509.0
HFD3_k127_1556812_5 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009867 497.0
HFD3_k127_1556812_6 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006361 477.0
HFD3_k127_1556812_7 NhaP-type Na H and K H antiporters with a unique C-terminal domain K11105 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000909 427.0
HFD3_k127_1556812_8 membrane protein terC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 391.0
HFD3_k127_1556812_9 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 387.0
HFD3_k127_157955_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K03520 - 1.2.5.3 3.526e-258 817.0
HFD3_k127_157955_1 HD domain - - - 4.587e-210 677.0
HFD3_k127_157955_10 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001666 242.0
HFD3_k127_157955_11 GyrI-like small molecule binding domain - - - 0.0000000000000000000000000000000000000000000000000754 191.0
HFD3_k127_157955_12 transcriptional regulator (MarR - - - 0.0000000000000000000000000000000006207 136.0
HFD3_k127_157955_13 - - - - 0.000000000000000000004781 98.0
HFD3_k127_157955_14 PFAM regulatory protein, ArsR K03892 - - 0.00000000000002379 76.0
HFD3_k127_157955_15 MacB-like periplasmic core domain K02004 - - 0.000000007668 58.0
HFD3_k127_157955_16 Flavodoxin domain K00230 - 1.3.5.3 0.0004564 50.0
HFD3_k127_157955_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 597.0
HFD3_k127_157955_3 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006892 508.0
HFD3_k127_157955_4 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000798 473.0
HFD3_k127_157955_5 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 465.0
HFD3_k127_157955_6 Voltage gated chloride channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007145 428.0
HFD3_k127_157955_7 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 342.0
HFD3_k127_157955_8 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008034 284.0
HFD3_k127_157955_9 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003972 268.0
HFD3_k127_161208_0 ATPases associated with a variety of cellular activities K10545 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 344.0
HFD3_k127_161208_1 Branched-chain amino acid transport system / permease component K10544 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 295.0
HFD3_k127_161208_2 electron transport chain K00347,K03614,K21163 - 1.6.5.8 0.000000000000000000000000000000000002573 151.0
HFD3_k127_1632210_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1583.0
HFD3_k127_1632210_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1088.0
HFD3_k127_1632210_10 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 404.0
HFD3_k127_1632210_11 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 374.0
HFD3_k127_1632210_12 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 364.0
HFD3_k127_1632210_13 Carbon-nitrogen hydrolase K01501 - 3.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 367.0
HFD3_k127_1632210_14 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 355.0
HFD3_k127_1632210_15 Belongs to the amidase family K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 357.0
HFD3_k127_1632210_16 hydratase K01617,K02509 - 4.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009656 324.0
HFD3_k127_1632210_17 COG1062 Zn-dependent alcohol dehydrogenases, class III K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 321.0
HFD3_k127_1632210_18 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 294.0
HFD3_k127_1632210_19 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002449 286.0
HFD3_k127_1632210_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 3.47e-321 993.0
HFD3_k127_1632210_20 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007238 264.0
HFD3_k127_1632210_21 protocatechuate 3,4-dioxygenase, beta subunit' K03381 - 1.13.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000005063 252.0
HFD3_k127_1632210_22 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K16201 - - 0.00000000000000000000000000000000000000000000000000000000000002717 228.0
HFD3_k127_1632210_23 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000008371 222.0
HFD3_k127_1632210_24 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000000003109 194.0
HFD3_k127_1632210_25 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.000000000000000000000000000000000000000000000001408 195.0
HFD3_k127_1632210_26 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000001658 179.0
HFD3_k127_1632210_27 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000005685 189.0
HFD3_k127_1632210_28 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000001856 175.0
HFD3_k127_1632210_29 proteolysis K19225 - 3.4.21.105 0.000000000000000000000000000000000000000001279 168.0
HFD3_k127_1632210_3 Phosphoglycerate kinase K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 558.0
HFD3_k127_1632210_30 PFAM Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000001533 164.0
HFD3_k127_1632210_31 TIGRFAM deazaflavin-dependent nitroreductase family protein - - - 0.0000000000000000000000000000000000000001582 160.0
HFD3_k127_1632210_32 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000006456 155.0
HFD3_k127_1632210_33 Phage integrase family - - - 0.000000000000000000000000000000000001376 143.0
HFD3_k127_1632210_34 Haem-degrading - - - 0.0000000000000000000000000000000002311 145.0
HFD3_k127_1632210_35 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000001882 134.0
HFD3_k127_1632210_36 Preprotein translocase SecG subunit K03075 - - 0.0000000000000000000000001779 107.0
HFD3_k127_1632210_37 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000293 118.0
HFD3_k127_1632210_38 Drug resistance transporter, bcr cfla subfamily K07552 - - 0.000000000000000000003948 102.0
HFD3_k127_1632210_39 phosphatase activity K07025 - - 0.00000004182 64.0
HFD3_k127_1632210_4 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483 - 1.14.14.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 551.0
HFD3_k127_1632210_40 TIGRFAM Drug resistance transporter Bcr CflA subfamily K07552 - - 0.0002586 47.0
HFD3_k127_1632210_5 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 542.0
HFD3_k127_1632210_6 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009016 518.0
HFD3_k127_1632210_7 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 462.0
HFD3_k127_1632210_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K00446 - 1.13.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 432.0
HFD3_k127_1632210_9 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004241 432.0
HFD3_k127_1641157_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.598e-289 899.0
HFD3_k127_1641157_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 7.331e-282 896.0
HFD3_k127_1641157_10 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 438.0
HFD3_k127_1641157_11 dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 421.0
HFD3_k127_1641157_12 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 406.0
HFD3_k127_1641157_13 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005253 372.0
HFD3_k127_1641157_14 transport system, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008778 343.0
HFD3_k127_1641157_15 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003738 344.0
HFD3_k127_1641157_16 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006329 357.0
HFD3_k127_1641157_17 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 346.0
HFD3_k127_1641157_18 PD-(D/E)XK nuclease superfamily K07465 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 328.0
HFD3_k127_1641157_19 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005793 331.0
HFD3_k127_1641157_2 Aminoacyl-tRNA editing domain K01881 - 6.1.1.15 4.502e-275 856.0
HFD3_k127_1641157_20 NMT1/THI5 like K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 316.0
HFD3_k127_1641157_21 PFAM 2-nitropropane dioxygenase NPD K02371 - 1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 295.0
HFD3_k127_1641157_22 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002405 277.0
HFD3_k127_1641157_23 tRNA processing K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005762 258.0
HFD3_k127_1641157_24 DSBA oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000006019 229.0
HFD3_k127_1641157_25 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000003581 235.0
HFD3_k127_1641157_26 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000004011 222.0
HFD3_k127_1641157_27 Copper resistance protein CopC K14166 - - 0.00000000000000000000000000000000000000000000000000000000002525 231.0
HFD3_k127_1641157_28 diacylglycerol O-acyltransferase K00635 GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700 2.3.1.20 0.000000000000000000000000000000000000000000000000000001314 195.0
HFD3_k127_1641157_29 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000000000000000000000000005879 177.0
HFD3_k127_1641157_3 Peptidase dimerisation domain - - - 2.111e-209 667.0
HFD3_k127_1641157_30 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000003623 178.0
HFD3_k127_1641157_31 Lumazine binding domain K00793 - 2.5.1.9 0.000000000000000000000000000000000000000001285 163.0
HFD3_k127_1641157_32 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000000000000000000003611 158.0
HFD3_k127_1641157_33 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000000001148 153.0
HFD3_k127_1641157_34 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000004442 128.0
HFD3_k127_1641157_35 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.00000000000000000004228 99.0
HFD3_k127_1641157_36 Domain of unkown function (DUF1775) - - - 0.0000000000000000007449 95.0
HFD3_k127_1641157_37 Protein of unknown function (DUF503) K09764 - - 0.0000000000000007631 80.0
HFD3_k127_1641157_38 Putative zinc-finger K03088 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000003379 71.0
HFD3_k127_1641157_4 Participates in both transcription termination and antitermination K02600 - - 1.998e-198 626.0
HFD3_k127_1641157_40 Chorismate mutase type II K04092 - 5.4.99.5 0.0000000009765 68.0
HFD3_k127_1641157_41 ribosomal protein L7Ae L30e S12e Gadd45 K07742 - - 0.000000001932 63.0
HFD3_k127_1641157_42 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K05606 - 5.1.99.1 0.00006702 53.0
HFD3_k127_1641157_43 - - - - 0.0002601 51.0
HFD3_k127_1641157_44 - - - - 0.0008862 50.0
HFD3_k127_1641157_5 geranylgeranyl reductase K21401 - 1.3.99.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 520.0
HFD3_k127_1641157_6 associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 489.0
HFD3_k127_1641157_7 acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 496.0
HFD3_k127_1641157_8 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 482.0
HFD3_k127_1641157_9 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008315 472.0
HFD3_k127_1645981_0 FAD dependent oxidoreductase central domain K00315 - 1.5.8.4 0.0 1060.0
HFD3_k127_1645981_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 4.211e-293 914.0
HFD3_k127_1645981_10 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 385.0
HFD3_k127_1645981_11 ATPases associated with a variety of cellular activities K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 362.0
HFD3_k127_1645981_12 His Kinase A (phosphoacceptor) domain K07768 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 320.0
HFD3_k127_1645981_13 PhoU domain K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004101 300.0
HFD3_k127_1645981_14 PFAM Iron-containing alcohol dehydrogenase K19714 GO:0003674,GO:0003824,GO:0004022,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.1.3.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001271 293.0
HFD3_k127_1645981_15 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000006295 220.0
HFD3_k127_1645981_16 collagen metabolic process K18546 - - 0.000000000000000000000000000000000000000000000000000000000005065 230.0
HFD3_k127_1645981_17 Fatty acid desaturase - - - 0.00000000000000000000000000000000000000000000000000000000003679 232.0
HFD3_k127_1645981_18 Protein of unknown function (DUF1638) - - - 0.0000000000000000000000000000000000000000000000000001773 192.0
HFD3_k127_1645981_19 Transcriptional regulatory protein, C terminal K07776 - - 0.000000000000000000000000000000000000000000001505 167.0
HFD3_k127_1645981_2 ABC transporter ATPase permease K06147 - - 1.423e-257 809.0
HFD3_k127_1645981_20 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.000000000000000000000000000000000001804 153.0
HFD3_k127_1645981_21 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.000000000000000000000000000000000002957 140.0
HFD3_k127_1645981_22 - - - - 0.000000000000000000000000000000000004239 140.0
HFD3_k127_1645981_23 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.000000000000000000000000000000000007997 139.0
HFD3_k127_1645981_24 transcriptional regulator - - - 0.00000000000000000001558 98.0
HFD3_k127_1645981_25 metallopeptidase activity - - - 0.0000000000003037 83.0
HFD3_k127_1645981_26 Virulence factor - - - 0.00000000000209 77.0
HFD3_k127_1645981_27 protein secretion K03116 - - 0.00000001646 58.0
HFD3_k127_1645981_3 Domain of unknown function (DUF4445) - - - 4.578e-232 747.0
HFD3_k127_1645981_4 ABC-type multidrug transport system ATPase and permease K06147,K06148 - - 1.07e-228 722.0
HFD3_k127_1645981_5 Trimethylamine methyltransferase (MTTB) - - - 2.989e-217 704.0
HFD3_k127_1645981_6 Trimethylamine methyltransferase (MTTB) - - - 3.776e-203 644.0
HFD3_k127_1645981_7 mandelate racemase muconate lactonizing K01856 - 5.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000526 516.0
HFD3_k127_1645981_8 CO dehydrogenase/acetyl-CoA synthase delta subunit K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 450.0
HFD3_k127_1645981_9 ROK family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007307 447.0
HFD3_k127_1653103_0 Glycosyl Transferase - - - 4.755e-281 885.0
HFD3_k127_1653103_1 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006791 499.0
HFD3_k127_1653103_2 Pfam Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006648 459.0
HFD3_k127_1653103_3 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007998 421.0
HFD3_k127_1653103_4 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 414.0
HFD3_k127_1653103_5 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000009123 231.0
HFD3_k127_1653103_6 COG1335 Amidases related to nicotinamidase - - - 0.00000000000000000000000000000000000000000000000000000001473 203.0
HFD3_k127_1653103_7 KR domain - - - 0.000000000000000000000000000000000000000000000000007128 186.0
HFD3_k127_1653103_8 Family of unknown function (DUF5317) - - - 0.0000000000000000000000000000000000000000207 164.0
HFD3_k127_1676713_0 galactose oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 458.0
HFD3_k127_1684935_0 Peptidase family S58 - - - 0.000000000000000000000000000000000000000007654 158.0
HFD3_k127_1684935_1 Fibronectin type 3 domain - - - 0.0000000000000000000000000000004141 128.0
HFD3_k127_1685895_0 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000039 199.0
HFD3_k127_1692518_0 DNA Topoisomerase IV K02469 - 5.99.1.3 0.0 1245.0
HFD3_k127_1692518_1 Molybdopterin oxidoreductase Fe4S4 domain - - - 4.847e-310 962.0
HFD3_k127_1692518_10 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 477.0
HFD3_k127_1692518_11 Cellulose biosynthesis protein BcsQ K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 440.0
HFD3_k127_1692518_12 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 457.0
HFD3_k127_1692518_13 Uncharacterised protein, DegV family COG1307 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 365.0
HFD3_k127_1692518_14 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003422 355.0
HFD3_k127_1692518_15 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 334.0
HFD3_k127_1692518_16 60Kd inner membrane protein K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 321.0
HFD3_k127_1692518_17 carboxylic ester hydrolase activity K01259,K19311 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 297.0
HFD3_k127_1692518_18 ParB-like nuclease domain K03497 GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005694,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0060187,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001044 278.0
HFD3_k127_1692518_19 Saccharopine dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003751 271.0
HFD3_k127_1692518_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 2.393e-258 811.0
HFD3_k127_1692518_20 Putative peptidoglycan binding domain K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000001504 261.0
HFD3_k127_1692518_21 Putative single-stranded nucleic acids-binding domain K06346 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000956 254.0
HFD3_k127_1692518_22 Serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000008269 231.0
HFD3_k127_1692518_23 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000003334 211.0
HFD3_k127_1692518_24 Integrase, catalytic region - - - 0.000000000000000000000000000000000000000000000001217 178.0
HFD3_k127_1692518_26 methyltransferase - - - 0.00000000000000000000000000000000000000000001209 169.0
HFD3_k127_1692518_27 Family of unknown function (DUF5318) - - - 0.00000000000000000000000000000000000000000001393 165.0
HFD3_k127_1692518_28 membrane - - - 0.00000000000000000000000000000000000000000004227 169.0
HFD3_k127_1692518_29 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000000000000000000001992 162.0
HFD3_k127_1692518_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 590.0
HFD3_k127_1692518_30 - - - - 0.0000000000000000000000000000000000000003748 171.0
HFD3_k127_1692518_31 belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000002261 143.0
HFD3_k127_1692518_32 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000002813 117.0
HFD3_k127_1692518_33 Single-strand binding protein family K03111 - - 0.0000000000000000000001473 102.0
HFD3_k127_1692518_34 Ribosomal RNA small subunit methyltransferase G K03501 - 2.1.1.170 0.0000000000000000000006469 102.0
HFD3_k127_1692518_35 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.00000000000000000000133 100.0
HFD3_k127_1692518_39 FR47-like protein - - - 0.000000000000000005385 98.0
HFD3_k127_1692518_4 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 577.0
HFD3_k127_1692518_40 Ribosomal protein L34 K02914 - - 0.0000000000003049 72.0
HFD3_k127_1692518_41 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 GO:0008150,GO:0040007 3.1.26.5 0.0000000107 62.0
HFD3_k127_1692518_5 Probable RNA and SrmB- binding site of polymerase A K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 572.0
HFD3_k127_1692518_6 MgtE intracellular N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007757 560.0
HFD3_k127_1692518_7 Luciferase-like monooxygenase K14733 - 1.14.13.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 524.0
HFD3_k127_1692518_8 DNA polymerase III beta subunit K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 494.0
HFD3_k127_1692518_9 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 487.0
HFD3_k127_1728243_0 Belongs to the amidase family K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007797 521.0
HFD3_k127_1728243_1 Glycerate kinase family K00865 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 369.0
HFD3_k127_1728243_2 Phosphoribulokinase / Uridine kinase family K00855,K00876 - 2.7.1.19,2.7.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000005951 249.0
HFD3_k127_1728243_5 - - - - 0.00001498 54.0
HFD3_k127_1735541_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1184.0
HFD3_k127_1735541_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 2.112e-222 696.0
HFD3_k127_1735541_10 DNA helicase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 398.0
HFD3_k127_1735541_11 Acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 356.0
HFD3_k127_1735541_12 von Willebrand factor type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 332.0
HFD3_k127_1735541_13 Tetrapyrrole (Corrin/Porphyrin) Methylases K02303,K13542 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 306.0
HFD3_k127_1735541_14 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005577 301.0
HFD3_k127_1735541_15 Cell envelope-related transcriptional attenuator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007228 291.0
HFD3_k127_1735541_16 Phosphoadenosine phosphosulfate reductase family K00390 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004604,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016667,GO:0016671,GO:0019344,GO:0019752,GO:0040007,GO:0043436,GO:0043866,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000169 256.0
HFD3_k127_1735541_17 Sugar (and other) transporter K08151 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001395 260.0
HFD3_k127_1735541_18 Aldolase/RraA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001275 245.0
HFD3_k127_1735541_19 lysR family - - - 0.000000000000000000000000000000000000000000000000000000004771 211.0
HFD3_k127_1735541_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 5.989e-198 623.0
HFD3_k127_1735541_20 TIGRFAM siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000000000008903 168.0
HFD3_k127_1735541_21 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000000000000001547 162.0
HFD3_k127_1735541_22 Mechanosensitive ion channel K22044 - - 0.00000000000000000000000000000000000000006515 168.0
HFD3_k127_1735541_23 glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.00000000000000000000000000000000000000123 152.0
HFD3_k127_1735541_24 ECF sigma factor K03088 - - 0.000000000000000000000000000000000000006652 153.0
HFD3_k127_1735541_25 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000001714 130.0
HFD3_k127_1735541_26 Mycofactocin system - - - 0.00000000000000000001024 94.0
HFD3_k127_1735541_27 Protein of unknown function (DUF559) - - - 0.0000000004603 70.0
HFD3_k127_1735541_3 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 603.0
HFD3_k127_1735541_4 Domain of unknown function (DUF4162) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 530.0
HFD3_k127_1735541_5 Alcohol dehydrogenase GroES-like domain K00121 - 1.1.1.1,1.1.1.284 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006799 523.0
HFD3_k127_1735541_6 Phosphoadenosine phosphosulfate reductase family K00957 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 421.0
HFD3_k127_1735541_7 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006793,GO:0006796,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:0071944,GO:1902494,GO:1902503,GO:1990234 2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008595 421.0
HFD3_k127_1735541_8 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 408.0
HFD3_k127_1735541_9 PFAM ATPase associated with various cellular activities, AAA_5 K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 391.0
HFD3_k127_1743024_0 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008195 544.0
HFD3_k127_1743024_1 Beta propeller domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006827 397.0
HFD3_k127_1743024_4 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000001155 134.0
HFD3_k127_1743024_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000007329 137.0
HFD3_k127_1743024_6 Nuclease-related domain - - - 0.0000000000000000000000571 106.0
HFD3_k127_1743024_7 Nuclease-related domain - - - 0.00002135 48.0
HFD3_k127_1751831_0 B3/4 domain K01890 - 6.1.1.20 2.095e-304 951.0
HFD3_k127_1751831_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 2.268e-210 659.0
HFD3_k127_1751831_10 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000372 253.0
HFD3_k127_1751831_11 Guanylate kinase homologues. K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000005156 253.0
HFD3_k127_1751831_12 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001217 247.0
HFD3_k127_1751831_13 Methyltransferase small domain K00564 - 2.1.1.172 0.0000000000000000000000000000000000000000000000000000000000000000002895 235.0
HFD3_k127_1751831_14 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000003795 212.0
HFD3_k127_1751831_15 Helix-hairpin-helix class 2 (Pol1 family) motifs - - - 0.0000000000000000000000000000000000000000000000000000000005504 209.0
HFD3_k127_1751831_16 SpoU rRNA Methylase family K03437 - - 0.0000000000000000000000000000000000000000000000000000002808 205.0
HFD3_k127_1751831_17 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000000000000001149 179.0
HFD3_k127_1751831_18 Helix-hairpin-helix DNA-binding motif class 1 - - - 0.000000000000000000000000000000000002637 143.0
HFD3_k127_1751831_19 - - - - 0.0000000000000000000000000000002704 126.0
HFD3_k127_1751831_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006216 563.0
HFD3_k127_1751831_20 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000004045 114.0
HFD3_k127_1751831_21 enzyme binding K00567,K07443 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 2.1.1.63 0.00000000000000000000000001782 113.0
HFD3_k127_1751831_22 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000001406 93.0
HFD3_k127_1751831_3 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 542.0
HFD3_k127_1751831_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000867 432.0
HFD3_k127_1751831_5 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 419.0
HFD3_k127_1751831_6 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 411.0
HFD3_k127_1751831_7 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007677 390.0
HFD3_k127_1751831_8 Protein of unknown function (DUF664) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 325.0
HFD3_k127_1751831_9 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 322.0
HFD3_k127_17800_0 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 608.0
HFD3_k127_17800_1 Winged helix DNA-binding domain K09927 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003976 505.0
HFD3_k127_17800_10 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000002049 152.0
HFD3_k127_17800_11 coenzyme F420 binding - - - 0.0000000000000000000000000000000003509 139.0
HFD3_k127_17800_12 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000005083 132.0
HFD3_k127_17800_13 Transcriptional regulator, arsR family - - - 0.00000000000003222 78.0
HFD3_k127_17800_2 Mo-co oxidoreductase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 414.0
HFD3_k127_17800_4 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 318.0
HFD3_k127_17800_5 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004508 281.0
HFD3_k127_17800_6 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002544 240.0
HFD3_k127_17800_7 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000002899 233.0
HFD3_k127_17800_8 Pfam Cation efflux - - - 0.0000000000000000000000000000000000000000000000000004675 194.0
HFD3_k127_17800_9 - - - - 0.00000000000000000000000000000000000000000000000002979 186.0
HFD3_k127_1780867_0 WD40-like Beta Propeller Repeat - - - 4.802e-226 719.0
HFD3_k127_1780867_1 diacylglycerol O-acyltransferase K00635 GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700 2.3.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 410.0
HFD3_k127_1780867_2 glutamine synthetase K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 392.0
HFD3_k127_1780867_3 Dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 327.0
HFD3_k127_1780867_4 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000001213 208.0
HFD3_k127_1780867_5 Peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000009064 173.0
HFD3_k127_1780867_7 - - - - 0.000000000000000003639 95.0
HFD3_k127_1844751_0 DEAD-like helicases superfamily K03724,K06877 - - 0.0 2123.0
HFD3_k127_1844751_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1454.0
HFD3_k127_1844751_10 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 1.31e-225 730.0
HFD3_k127_1844751_100 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000009174 179.0
HFD3_k127_1844751_101 cell redox homeostasis K02199 - - 0.00000000000000000000000000000000000000000000001037 179.0
HFD3_k127_1844751_102 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000003669 175.0
HFD3_k127_1844751_103 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000000000000000005616 173.0
HFD3_k127_1844751_104 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000001323 173.0
HFD3_k127_1844751_106 AzlC protein - - - 0.000000000000000000000000000000000000000000004984 179.0
HFD3_k127_1844751_107 Sortase family K07284 - 3.4.22.70 0.00000000000000000000000000000000000000000001914 176.0
HFD3_k127_1844751_108 Belongs to the P(II) protein family K04751 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0008150,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043531,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000001048 160.0
HFD3_k127_1844751_11 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term K00441 - 1.12.98.1 8.043e-217 676.0
HFD3_k127_1844751_110 - - - - 0.0000000000000000000000000000000000000006842 160.0
HFD3_k127_1844751_111 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000004273 156.0
HFD3_k127_1844751_112 proton-transporting ATP synthase activity, rotational mechanism K02114 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000001638 148.0
HFD3_k127_1844751_113 subunit of a heme lyase K02200 - - 0.0000000000000000000000000000000000002148 154.0
HFD3_k127_1844751_114 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.000000000000000000000000000000000004589 139.0
HFD3_k127_1844751_115 phosphohistidine phosphatase, SixA K03574,K08296 - 3.6.1.55 0.0000000000000000000000000000000001344 142.0
HFD3_k127_1844751_116 Flavodoxin reductases ferredoxin-NADPH reductases family 1 - - - 0.000000000000000000000000000000000175 144.0
HFD3_k127_1844751_118 ATP synthesis coupled proton transport K02109 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0016020,GO:0016469,GO:0032991,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 - 0.000000000000000000000000000000003687 135.0
HFD3_k127_1844751_12 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 2.257e-213 680.0
HFD3_k127_1844751_120 Binds the 23S rRNA K02909 - - 0.000000000000000000000000000002971 127.0
HFD3_k127_1844751_121 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000000001098 119.0
HFD3_k127_1844751_122 NifU-like domain - - - 0.0000000000000000000000000225 116.0
HFD3_k127_1844751_123 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000003783 121.0
HFD3_k127_1844751_126 Protein of unknown function (DUF3107) - - - 0.000000000000000000001839 96.0
HFD3_k127_1844751_129 Domain of unknown function (DUF4190) - - - 0.00000000009225 67.0
HFD3_k127_1844751_13 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 3.304e-212 677.0
HFD3_k127_1844751_131 Branched-chain amino acid transport protein (AzlD) - - - 0.000000002631 69.0
HFD3_k127_1844751_133 - - - - 0.0000006594 61.0
HFD3_k127_1844751_14 Glycosyl transferase 4-like domain - - - 2.869e-211 662.0
HFD3_k127_1844751_15 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 2.64e-207 651.0
HFD3_k127_1844751_16 Aldehyde dehydrogenase family K00128 - 1.2.1.3 8.52e-199 632.0
HFD3_k127_1844751_17 Ammonium Transporter Family K03320 - - 2.367e-195 621.0
HFD3_k127_1844751_18 Histidine kinase K00936 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007123 604.0
HFD3_k127_1844751_19 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008685 599.0
HFD3_k127_1844751_2 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.4.1.1 3.467e-301 950.0
HFD3_k127_1844751_20 Homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 599.0
HFD3_k127_1844751_21 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 588.0
HFD3_k127_1844751_22 Acetyl-CoA acetyltransferase K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008874 584.0
HFD3_k127_1844751_23 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 578.0
HFD3_k127_1844751_24 AlkA N-terminal domain K13529 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 577.0
HFD3_k127_1844751_25 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 569.0
HFD3_k127_1844751_26 Major facilitator Superfamily K08369 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008342 536.0
HFD3_k127_1844751_27 PFAM Glycoside hydrolase 15-related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006449 512.0
HFD3_k127_1844751_28 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 GO:0008150,GO:0040007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 510.0
HFD3_k127_1844751_29 Cytochrome C assembly protein K02198,K04016 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005037 515.0
HFD3_k127_1844751_3 AAA domain - - - 5.089e-287 950.0
HFD3_k127_1844751_30 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 495.0
HFD3_k127_1844751_31 Aminotransferase class-V K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 481.0
HFD3_k127_1844751_32 ArgK protein K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009963 473.0
HFD3_k127_1844751_33 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 474.0
HFD3_k127_1844751_34 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000071 468.0
HFD3_k127_1844751_35 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 464.0
HFD3_k127_1844751_36 Electron transfer flavoprotein domain K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 462.0
HFD3_k127_1844751_37 Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009323 460.0
HFD3_k127_1844751_38 Ammonium Transporter Family K03320 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 461.0
HFD3_k127_1844751_39 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008773,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0030312,GO:0044464,GO:0070566,GO:0070569,GO:0071944,GO:0140096 2.7.7.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 476.0
HFD3_k127_1844751_4 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901576 2.4.1.18 3.024e-281 885.0
HFD3_k127_1844751_40 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005123 451.0
HFD3_k127_1844751_41 tRNA methyl transferase K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 451.0
HFD3_k127_1844751_42 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005597 447.0
HFD3_k127_1844751_43 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 458.0
HFD3_k127_1844751_44 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K01459 - 3.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009855 437.0
HFD3_k127_1844751_45 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 430.0
HFD3_k127_1844751_46 PFAM Glycosyl transferase, group 1 K16150 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 433.0
HFD3_k127_1844751_47 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009113 430.0
HFD3_k127_1844751_48 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 426.0
HFD3_k127_1844751_49 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004173 433.0
HFD3_k127_1844751_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 5.368e-277 858.0
HFD3_k127_1844751_50 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006295 404.0
HFD3_k127_1844751_51 Flavin containing amine oxidoreductase K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 409.0
HFD3_k127_1844751_52 nucleoside hydrolase K01239,K01250,K10213 - 3.2.2.1,3.2.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 387.0
HFD3_k127_1844751_53 Transcriptional regulator - GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009405,GO:0010468,GO:0010565,GO:0016020,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0044419,GO:0044464,GO:0050789,GO:0050794,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 379.0
HFD3_k127_1844751_54 alpha/beta hydrolase fold K01066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003695 352.0
HFD3_k127_1844751_55 iron dependent repressor K03709 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006355,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009058,GO:0009237,GO:0009712,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016151,GO:0018958,GO:0019184,GO:0019219,GO:0019222,GO:0019290,GO:0019540,GO:0019748,GO:0030145,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0044550,GO:0045892,GO:0045934,GO:0046870,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0050897,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 341.0
HFD3_k127_1844751_56 dihydroorotate dehydrogenase activity K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 347.0
HFD3_k127_1844751_57 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 350.0
HFD3_k127_1844751_58 membrane protein terC K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 344.0
HFD3_k127_1844751_59 Acyl-CoA thioesterase K10805 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 344.0
HFD3_k127_1844751_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 3.412e-258 802.0
HFD3_k127_1844751_60 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005363 343.0
HFD3_k127_1844751_61 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 336.0
HFD3_k127_1844751_62 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 347.0
HFD3_k127_1844751_63 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007197 336.0
HFD3_k127_1844751_64 Histidine phosphatase superfamily (branch 1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 316.0
HFD3_k127_1844751_65 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 317.0
HFD3_k127_1844751_66 Methyltransferase small domain K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007723 324.0
HFD3_k127_1844751_67 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006641 318.0
HFD3_k127_1844751_68 Phosphatidylinositol - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007731 318.0
HFD3_k127_1844751_69 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 312.0
HFD3_k127_1844751_7 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.437e-253 799.0
HFD3_k127_1844751_70 DJ-1 PfpI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 304.0
HFD3_k127_1844751_71 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 306.0
HFD3_k127_1844751_72 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005297 313.0
HFD3_k127_1844751_73 Sortase family K07284 - 3.4.22.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 304.0
HFD3_k127_1844751_74 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 293.0
HFD3_k127_1844751_75 Major Facilitator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 307.0
HFD3_k127_1844751_76 Cytochrome C assembly protein K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008866 299.0
HFD3_k127_1844751_77 Glucose dehydrogenase C-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009204 291.0
HFD3_k127_1844751_78 ATPases associated with a variety of cellular activities K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001043 281.0
HFD3_k127_1844751_79 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002477 293.0
HFD3_k127_1844751_8 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 2.629e-234 737.0
HFD3_k127_1844751_80 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001844 292.0
HFD3_k127_1844751_81 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008964 264.0
HFD3_k127_1844751_82 CcmB protein K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005447 279.0
HFD3_k127_1844751_83 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008608 254.0
HFD3_k127_1844751_84 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000004472 239.0
HFD3_k127_1844751_85 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000004237 243.0
HFD3_k127_1844751_86 Trypsin-like serine protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000006871 244.0
HFD3_k127_1844751_87 Protein of unknown function (DUF3090) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001592 234.0
HFD3_k127_1844751_88 Aldose 1-epimerase K01785 - 5.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000004362 237.0
HFD3_k127_1844751_89 PFAM oxidoreductase, molybdopterin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000001113 230.0
HFD3_k127_1844751_9 acyl-CoA dehydrogenase - - - 1.752e-226 706.0
HFD3_k127_1844751_90 PFAM Sodium hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000793 248.0
HFD3_k127_1844751_91 - - - - 0.0000000000000000000000000000000000000000000000000000000000000013 231.0
HFD3_k127_1844751_92 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000003448 213.0
HFD3_k127_1844751_93 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000002636 207.0
HFD3_k127_1844751_94 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0000000000000000000000000000000000000000000000000000006971 201.0
HFD3_k127_1844751_95 - - - - 0.00000000000000000000000000000000000000000000000000001854 199.0
HFD3_k127_1844751_96 Sterol carrier protein - - - 0.000000000000000000000000000000000000000000000000000723 186.0
HFD3_k127_1844751_97 Hydrolase of the alpha beta-hydrolase K07020 - - 0.000000000000000000000000000000000000000000000000002892 187.0
HFD3_k127_1844751_98 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000000001333 185.0
HFD3_k127_1844751_99 - - - - 0.0000000000000000000000000000000000000000000000008666 179.0
HFD3_k127_1850303_0 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000001186 190.0
HFD3_k127_1850303_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000006509 116.0
HFD3_k127_1878177_0 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 411.0
HFD3_k127_1891843_0 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 472.0
HFD3_k127_1891843_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K02549,K19802,K21624 - 4.2.1.113,4.2.1.171,5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 432.0
HFD3_k127_1891843_2 Arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004837 419.0
HFD3_k127_1891843_3 Domain of unknown function (DUF1989) K09967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 411.0
HFD3_k127_1891843_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 373.0
HFD3_k127_1891843_5 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 359.0
HFD3_k127_1891843_6 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 344.0
HFD3_k127_1891843_7 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 336.0
HFD3_k127_1891843_8 EamA-like transporter family - - - 0.00000002036 64.0
HFD3_k127_19223_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 7.459e-252 788.0
HFD3_k127_19223_1 Thiamine pyrophosphate enzyme, central domain K03336 - 3.7.1.22 2.175e-221 703.0
HFD3_k127_19223_10 DNA polymerase LigD polymerase domain K01971,K10747 GO:0000166,GO:0000287,GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0003909,GO:0003910,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0004652,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006269,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016874,GO:0016886,GO:0016895,GO:0017076,GO:0018130,GO:0019438,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0033554,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070566,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0097747,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 421.0
HFD3_k127_19223_11 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000486 435.0
HFD3_k127_19223_12 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004759 417.0
HFD3_k127_19223_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 375.0
HFD3_k127_19223_14 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050790,GO:0050896,GO:0051340,GO:0051351,GO:0051716,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005835 368.0
HFD3_k127_19223_15 ABC transporter K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005649 379.0
HFD3_k127_19223_16 Domain of unknown function (DUF1731) K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 349.0
HFD3_k127_19223_17 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 351.0
HFD3_k127_19223_18 Myo-inositol 2-dehydrogenase K18652 - 1.1.1.361 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 335.0
HFD3_k127_19223_19 4-hydroxybenzoate 3-monooxygenase K00481 - 1.14.13.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005712 338.0
HFD3_k127_19223_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 1.724e-209 662.0
HFD3_k127_19223_20 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 312.0
HFD3_k127_19223_21 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004354 308.0
HFD3_k127_19223_22 Rhomboid family K19225 - 3.4.21.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000398 284.0
HFD3_k127_19223_23 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000006228 275.0
HFD3_k127_19223_24 COG1082 Sugar phosphate isomerases epimerases K03335 - 4.2.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000006424 252.0
HFD3_k127_19223_25 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004665 258.0
HFD3_k127_19223_26 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000006904 213.0
HFD3_k127_19223_27 Protein of unknown function (DUF664) - - - 0.0000000000000000000000000000000000000000000000000000000006545 207.0
HFD3_k127_19223_28 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000007256 190.0
HFD3_k127_19223_29 (ABC) transporter - - - 0.00000000000000000000000000000000000000000000000001876 193.0
HFD3_k127_19223_3 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 2.919e-201 654.0
HFD3_k127_19223_30 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000001544 180.0
HFD3_k127_19223_31 - - - - 0.0000000000000000000000000000000000000001607 154.0
HFD3_k127_19223_32 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000578 145.0
HFD3_k127_19223_33 - - - - 0.000000000000000000000000000002311 139.0
HFD3_k127_19223_35 - - - - 0.0000000000000000000003758 108.0
HFD3_k127_19223_36 Uncharacterised nucleotidyltransferase - - - 0.000000000000000001105 99.0
HFD3_k127_19223_37 Transglutaminase-like superfamily - - - 0.00000000000001651 79.0
HFD3_k127_19223_39 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0000000001415 69.0
HFD3_k127_19223_4 e3 binding domain K00658 - 2.3.1.61 4.47e-197 625.0
HFD3_k127_19223_5 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007262 552.0
HFD3_k127_19223_6 MMPL family K06994 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 569.0
HFD3_k127_19223_7 Creatinase/Prolidase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005122 527.0
HFD3_k127_19223_8 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 524.0
HFD3_k127_19223_9 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 451.0
HFD3_k127_1996532_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1668.0
HFD3_k127_1996532_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 1.513e-233 750.0
HFD3_k127_1996532_10 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005046 293.0
HFD3_k127_1996532_11 Creatinase/Prolidase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 297.0
HFD3_k127_1996532_12 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001415 270.0
HFD3_k127_1996532_13 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000000001562 230.0
HFD3_k127_1996532_14 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000003569 214.0
HFD3_k127_1996532_15 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000003654 189.0
HFD3_k127_1996532_16 Catalyzes a trans-dehydration via an enolate intermediate K03786,K16021 - 4.2.1.10 0.00000000000000000000000000000000000000000000000008679 190.0
HFD3_k127_1996532_17 Predicted membrane protein (DUF2079) K07778 - 2.7.13.3 0.000000000000000000000000000000000000005481 164.0
HFD3_k127_1996532_18 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000001087 153.0
HFD3_k127_1996532_19 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000000000000000000001959 154.0
HFD3_k127_1996532_2 GTP-binding protein TypA K06207 - - 1.763e-206 659.0
HFD3_k127_1996532_20 rRNA (adenine-N6,N6-)-dimethyltransferase activity K02528,K20444 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000527 130.0
HFD3_k127_1996532_22 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000005324 88.0
HFD3_k127_1996532_23 molybdenum cofactor guanylyltransferase activity K03637,K03752,K13818 - 2.7.7.77,4.6.1.17 0.00000000000001036 78.0
HFD3_k127_1996532_24 COG0607 Rhodanese-related sulfurtransferase - - - 0.0000000000001232 74.0
HFD3_k127_1996532_3 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 604.0
HFD3_k127_1996532_4 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 481.0
HFD3_k127_1996532_5 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000847 469.0
HFD3_k127_1996532_6 3-dehydroquinate synthase K16020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 434.0
HFD3_k127_1996532_7 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004469 412.0
HFD3_k127_1996532_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 324.0
HFD3_k127_1996532_9 chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 294.0
HFD3_k127_2000591_0 PA domain - - - 2.526e-310 981.0
HFD3_k127_2000591_1 Ribonuclease E/G family K08300,K08301 - 3.1.26.12 2.061e-231 732.0
HFD3_k127_2000591_10 Cell cycle protein K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004142 461.0
HFD3_k127_2000591_11 Phosphohydrolase-associated domain K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 458.0
HFD3_k127_2000591_12 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 403.0
HFD3_k127_2000591_13 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008332 353.0
HFD3_k127_2000591_14 Phage shock protein A K03969 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008271 311.0
HFD3_k127_2000591_15 Cysteine desulfurase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 293.0
HFD3_k127_2000591_16 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000001241 229.0
HFD3_k127_2000591_17 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000000000000000000005943 158.0
HFD3_k127_2000591_18 - K03571 - - 0.0000000000000000000000000000000000000127 150.0
HFD3_k127_2000591_19 - - - - 0.0000000000000000000000000000000000008877 148.0
HFD3_k127_2000591_2 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 6.295e-227 727.0
HFD3_k127_2000591_20 Ribosomal L27 protein K02899 - - 0.000000000000000000000000000000002174 136.0
HFD3_k127_2000591_22 - - - - 0.00000000000000001243 90.0
HFD3_k127_2000591_23 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000866 79.0
HFD3_k127_2000591_24 STAS domain - - - 0.0000004544 54.0
HFD3_k127_2000591_3 ClpX C4-type zinc finger K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030312,GO:0030554,GO:0031333,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0044087,GO:0044238,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 2.394e-206 648.0
HFD3_k127_2000591_4 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 6.855e-200 631.0
HFD3_k127_2000591_5 Cell division protein FtsA K03569 - - 8.981e-199 623.0
HFD3_k127_2000591_6 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 582.0
HFD3_k127_2000591_7 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004329 554.0
HFD3_k127_2000591_8 Polysaccharide biosynthesis C-terminal domain K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008493 532.0
HFD3_k127_2000591_9 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 512.0
HFD3_k127_2188587_0 Belongs to the GcvT family - - - 0.0 1056.0
HFD3_k127_2188587_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 314.0
HFD3_k127_2188587_2 Electron transfer flavoprotein domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004505 280.0
HFD3_k127_2188587_3 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002141 265.0
HFD3_k127_2188587_4 gntR family - - - 0.00000000000000000000000000000005068 133.0
HFD3_k127_2328205_0 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008571 531.0
HFD3_k127_2328205_1 M18 family aminopeptidase K01267 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.11.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 493.0
HFD3_k127_2328205_2 Phosphoglycerate mutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001354 250.0
HFD3_k127_2328205_3 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000003719 196.0
HFD3_k127_2328205_4 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000002283 138.0
HFD3_k127_2328205_5 Protein of unknown function (DUF3151) - - - 0.0000000000000000006303 89.0
HFD3_k127_2342465_0 Belongs to the GcvT family K19191 GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006575,GO:0006576,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008480,GO:0009056,GO:0009063,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016491,GO:0016645,GO:0019695,GO:0019752,GO:0019842,GO:0031406,GO:0031974,GO:0033218,GO:0034641,GO:0035999,GO:0036094,GO:0042133,GO:0042135,GO:0042219,GO:0042402,GO:0042426,GO:0042558,GO:0043167,GO:0043168,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0046483,GO:0046653,GO:0046997,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0055114,GO:0065007,GO:0065008,GO:0070013,GO:0071704,GO:0072341,GO:0097159,GO:0097164,GO:1901052,GO:1901053,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.5.3.19 0.0 1320.0
HFD3_k127_2342465_1 FAD dependent oxidoreductase K19191 - 1.5.3.19 0.0 1075.0
HFD3_k127_2342465_10 Substrate binding domain of ABC-type glycine betaine transport system K02002 - - 0.000000000000000000000000000000000000000000000000000000000000000001628 240.0
HFD3_k127_2342465_11 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000008519 213.0
HFD3_k127_2342465_12 transcriptional regulator - - - 0.000000000000000000000000000000000000000007987 163.0
HFD3_k127_2342465_13 Exopolysaccharide synthesis, ExoD - - - 0.00000000000000000000000000000000000001252 151.0
HFD3_k127_2342465_14 glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.0000000000000261 74.0
HFD3_k127_2342465_15 NADH:flavin oxidoreductase / NADH oxidase family K21833 - - 0.00000000001185 64.0
HFD3_k127_2342465_2 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate K00108 - 1.1.99.1 8.864e-287 888.0
HFD3_k127_2342465_3 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 7.925e-277 860.0
HFD3_k127_2342465_4 Saccharopine dehydrogenase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009486 462.0
HFD3_k127_2342465_5 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 406.0
HFD3_k127_2342465_6 glycine betaine K02000 - 3.6.3.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 410.0
HFD3_k127_2342465_7 ABC-type proline glycine betaine transport system permease component K02001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004412 411.0
HFD3_k127_2342465_8 Choline/ethanolamine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008264 355.0
HFD3_k127_2342465_9 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000454 268.0
HFD3_k127_2354322_0 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 589.0
HFD3_k127_2354322_1 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain - - - 0.000000000000000000000000000000000000000000000000001357 188.0
HFD3_k127_2354322_2 EamA-like transporter family - - - 0.00000000000000000000003982 111.0
HFD3_k127_2354322_3 - - - - 0.0000000000000000000001198 99.0
HFD3_k127_2354322_5 - - - - 0.0000006531 55.0
HFD3_k127_2371676_0 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 527.0
HFD3_k127_2371676_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 478.0
HFD3_k127_2371676_2 histidine kinase, dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 461.0
HFD3_k127_2371676_3 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 349.0
HFD3_k127_2371676_4 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008804 323.0
HFD3_k127_2371676_5 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 304.0
HFD3_k127_2371676_6 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002127 257.0
HFD3_k127_2371676_7 Protein of unknown function (DUF3500) - - - 0.00000000000000000000000000000000000000000000000002 184.0
HFD3_k127_2371676_8 FtsX-like permease family - - - 0.0000000000000000000000000000000000000005687 171.0
HFD3_k127_2371676_9 PFAM response regulator receiver K07689 - - 0.000000000000000000000000008287 118.0
HFD3_k127_2377460_0 ATPase P-type (Transporting), HAD superfamily, subfamily IC - - - 0.0 1057.0
HFD3_k127_2377460_1 Belongs to the proline racemase family K01777 - 5.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 503.0
HFD3_k127_2377460_10 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 296.0
HFD3_k127_2377460_11 Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 290.0
HFD3_k127_2377460_12 belongs to the sigma-70 factor family K03090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 288.0
HFD3_k127_2377460_13 Choline/ethanolamine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002475 277.0
HFD3_k127_2377460_14 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001022 267.0
HFD3_k127_2377460_15 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000003138 239.0
HFD3_k127_2377460_16 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000002716 226.0
HFD3_k127_2377460_17 protein phosphatase 2C domain protein - - - 0.00000000000000000000000000000000000000000000000000000008568 221.0
HFD3_k127_2377460_18 - - - - 0.00000000000000000000000000000000000000000000000000006072 192.0
HFD3_k127_2377460_19 RNA polymerase sigma factor, sigma-70 family K03090 GO:0000988,GO:0000990,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0006629,GO:0006950,GO:0006979,GO:0006995,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009409,GO:0009605,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016987,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034059,GO:0036293,GO:0042221,GO:0042594,GO:0043175,GO:0043254,GO:0043562,GO:0044087,GO:0044238,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0070417,GO:0070482,GO:0071496,GO:0071704,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2000142,GO:2001141 - 0.000000000000000000000000000000000000000000000000000132 199.0
HFD3_k127_2377460_2 cobalamin binding K20450 - 5.4.99.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 467.0
HFD3_k127_2377460_20 Protein of unknown function (DUF1345) - - - 0.00000000000000000000000000000000000000000000000005181 188.0
HFD3_k127_2377460_21 - - - - 0.000000000000000000000000000000000000000009873 160.0
HFD3_k127_2377460_22 ACT domain protein - - - 0.000000000000000000000000000000000000003554 149.0
HFD3_k127_2377460_23 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046983,GO:0070037,GO:0070038,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.177 0.000000000000000000000000000000000000293 154.0
HFD3_k127_2377460_24 Transcriptional regulator - - - 0.000000000000000000000000000000000001082 149.0
HFD3_k127_2377460_25 LuxR family transcriptional regulator - - - 0.000000000000000000000000000000004655 141.0
HFD3_k127_2377460_26 Bacterial transcriptional repressor C-terminal - - - 0.000000000000000000000000000001119 128.0
HFD3_k127_2377460_27 Belongs to the CinA family - - - 0.000000000000000000000001847 113.0
HFD3_k127_2377460_28 transcriptional regulator K19333 - - 0.00000000000000000000003143 111.0
HFD3_k127_2377460_29 antisigma factor binding K04749 - - 0.000000000000001298 80.0
HFD3_k127_2377460_3 helix_turn _helix lactose operon repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 454.0
HFD3_k127_2377460_30 diguanylate cyclase - - - 0.000000000000003124 86.0
HFD3_k127_2377460_32 Histidine kinase-like ATPase domain - - - 0.000000006179 64.0
HFD3_k127_2377460_33 anti-sigma regulatory factor K04757 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036094,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 2.7.11.1 0.000000008289 62.0
HFD3_k127_2377460_35 exodeoxyribonuclease III K01142 - 3.1.11.2 0.00004131 49.0
HFD3_k127_2377460_36 Universal stress protein - - - 0.0001342 53.0
HFD3_k127_2377460_37 Histidine kinase-like ATPase domain - - - 0.0002042 49.0
HFD3_k127_2377460_38 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B) K04757 GO:0000988,GO:0000989,GO:0003674,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 2.7.11.1 0.0003989 50.0
HFD3_k127_2377460_4 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 GO:0003674,GO:0003824,GO:0004333,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0071944,GO:0072350 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 422.0
HFD3_k127_2377460_5 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 420.0
HFD3_k127_2377460_6 WYL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 372.0
HFD3_k127_2377460_7 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 361.0
HFD3_k127_2377460_8 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 365.0
HFD3_k127_2377460_9 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 340.0
HFD3_k127_2408782_0 Rieske 2Fe-2S K14952 - - 1.388e-217 687.0
HFD3_k127_2408782_1 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 335.0
HFD3_k127_2408782_10 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000001584 183.0
HFD3_k127_2408782_11 Redoxin - - - 0.00000000000000000000000000000000000000299 155.0
HFD3_k127_2408782_12 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000004226 148.0
HFD3_k127_2408782_13 cyclic nucleotide binding K07001,K10914 - - 0.00000000000000000000000000000000008495 141.0
HFD3_k127_2408782_14 PFAM Disulfide bond formation protein DsbB K03611 - - 0.0000000000000000000000000000000009026 137.0
HFD3_k127_2408782_15 - - - - 0.0000000000000000000000000000006084 124.0
HFD3_k127_2408782_16 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000001351 124.0
HFD3_k127_2408782_17 endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000008044 113.0
HFD3_k127_2408782_18 Protein of unknown function (DUF2510) - - - 0.00000000000000001348 92.0
HFD3_k127_2408782_20 Putative zinc-finger - - - 0.00000000000002608 79.0
HFD3_k127_2408782_21 lipolytic protein G-D-S-L family K01183 - 3.2.1.14 0.0000000002324 70.0
HFD3_k127_2408782_22 Putative zinc-finger - - - 0.0000000003442 63.0
HFD3_k127_2408782_23 procollagen-lysine 5-dioxygenase activity K00473,K13645,K13646,K13647,K15174 GO:0000003,GO:0000902,GO:0000904,GO:0001666,GO:0001701,GO:0001885,GO:0001886,GO:0002009,GO:0002064,GO:0003006,GO:0003008,GO:0003013,GO:0003018,GO:0003158,GO:0003382,GO:0003674,GO:0003824,GO:0003980,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0005791,GO:0005794,GO:0005802,GO:0006011,GO:0006082,GO:0006139,GO:0006464,GO:0006486,GO:0006493,GO:0006520,GO:0006575,GO:0006725,GO:0006793,GO:0006807,GO:0006950,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007295,GO:0007399,GO:0008015,GO:0008104,GO:0008150,GO:0008152,GO:0008194,GO:0008198,GO:0008378,GO:0008475,GO:0008544,GO:0008652,GO:0009058,GO:0009059,GO:0009066,GO:0009067,GO:0009100,GO:0009101,GO:0009225,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009987,GO:0010033,GO:0012505,GO:0016020,GO:0016043,GO:0016053,GO:0016491,GO:0016705,GO:0016706,GO:0016740,GO:0016757,GO:0016758,GO:0017185,GO:0018126,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0019842,GO:0019953,GO:0021915,GO:0022412,GO:0022414,GO:0022607,GO:0030154,GO:0030198,GO:0030199,GO:0030246,GO:0030323,GO:0030324,GO:0030855,GO:0030867,GO:0031012,GO:0031090,GO:0031406,GO:0031418,GO:0031984,GO:0032501,GO:0032502,GO:0032504,GO:0032870,GO:0032963,GO:0032964,GO:0032989,GO:0032991,GO:0033036,GO:0033218,GO:0033823,GO:0034641,GO:0034645,GO:0035150,GO:0035250,GO:0035251,GO:0035295,GO:0035296,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042175,GO:0042221,GO:0042277,GO:0042311,GO:0042398,GO:0042802,GO:0042803,GO:0043009,GO:0043062,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043413,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045446,GO:0046394,GO:0046483,GO:0046527,GO:0046872,GO:0046914,GO:0046946,GO:0046947,GO:0046983,GO:0048029,GO:0048037,GO:0048468,GO:0048471,GO:0048477,GO:0048513,GO:0048589,GO:0048609,GO:0048729,GO:0048730,GO:0048731,GO:0048856,GO:0048869,GO:0050211,GO:0050662,GO:0050880,GO:0050896,GO:0051179,GO:0051213,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060425,GO:0060429,GO:0060541,GO:0062023,GO:0065007,GO:0065008,GO:0070085,GO:0070482,GO:0070815,GO:0070831,GO:0070887,GO:0071310,GO:0071495,GO:0071704,GO:0071711,GO:0071840,GO:0090066,GO:0097359,GO:0097435,GO:0097746,GO:0097755,GO:0098588,GO:0098791,GO:0098827,GO:0140096,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 1.14.11.4,2.4.1.50,2.4.1.66 0.000003531 57.0
HFD3_k127_2408782_24 - - - - 0.0002764 51.0
HFD3_k127_2408782_3 ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002134 278.0
HFD3_k127_2408782_4 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001289 258.0
HFD3_k127_2408782_5 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002457 261.0
HFD3_k127_2408782_6 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002105 268.0
HFD3_k127_2408782_7 hydratase K02509 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001884 250.0
HFD3_k127_2408782_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000008239 203.0
HFD3_k127_2408782_9 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000002068 200.0
HFD3_k127_2427999_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 1.774e-213 670.0
HFD3_k127_2427999_1 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 514.0
HFD3_k127_2427999_10 PFAM helix-turn-helix HxlR type - - - 0.0000000000000000000000000000000007053 138.0
HFD3_k127_2427999_11 Competence-damaged protein K03743 - 3.5.1.42 0.00000000000000000000000000006585 121.0
HFD3_k127_2427999_12 Thioesterase-like superfamily - - - 0.0000000003796 70.0
HFD3_k127_2427999_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 434.0
HFD3_k127_2427999_3 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000006341 207.0
HFD3_k127_2427999_4 Rieske 2Fe-2S K00479 - - 0.00000000000000000000000000000000000000000000000000000004144 209.0
HFD3_k127_2427999_5 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000002466 198.0
HFD3_k127_2427999_6 Electron transfer DM13 - - - 0.00000000000000000000000000000000000000000000000000005718 192.0
HFD3_k127_2427999_7 CoA binding domain K06929 - - 0.00000000000000000000000000000000000000000000002464 194.0
HFD3_k127_2427999_8 DNA repair protein - - - 0.0000000000000000000000000000000000000000000008851 175.0
HFD3_k127_2427999_9 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000006339 142.0
HFD3_k127_2444866_0 Belongs to the aldehyde dehydrogenase family K00151 - 1.2.1.60 6.862e-226 709.0
HFD3_k127_2444866_1 Belongs to the thiolase family - - - 1.511e-215 674.0
HFD3_k127_2444866_10 PFAM regulatory protein ArsR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 379.0
HFD3_k127_2444866_11 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 358.0
HFD3_k127_2444866_12 Zinc-binding dehydrogenase K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006297 338.0
HFD3_k127_2444866_13 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 327.0
HFD3_k127_2444866_14 F420-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 312.0
HFD3_k127_2444866_15 SMP-30/Gluconolaconase/LRE-like region K01053,K14274 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 308.0
HFD3_k127_2444866_16 SMP-30/Gluconolaconase/LRE-like region K01053,K14274 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 311.0
HFD3_k127_2444866_17 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005355 311.0
HFD3_k127_2444866_18 Methylenetetrahydrofolate reductase K00297 GO:0003674,GO:0003824,GO:0004489,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 291.0
HFD3_k127_2444866_19 electron transport chain K00347,K03614,K21163 - 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002168 294.0
HFD3_k127_2444866_2 AMP-binding enzyme C-terminal domain K18661 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 548.0
HFD3_k127_2444866_20 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001966 277.0
HFD3_k127_2444866_21 Enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008218 254.0
HFD3_k127_2444866_22 Periplasmic binding protein domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000369 258.0
HFD3_k127_2444866_23 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000002624 260.0
HFD3_k127_2444866_24 reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000008919 237.0
HFD3_k127_2444866_25 import. Responsible for energy coupling to the transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000001687 240.0
HFD3_k127_2444866_26 - - - - 0.000000000000000000000000000000000000000000000000000000000000000005995 249.0
HFD3_k127_2444866_27 gntR family - - - 0.0000000000000000000000000000000000000000000000000000000000006331 220.0
HFD3_k127_2444866_28 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.0000000000000000000000000000000000000000000000000000000001451 206.0
HFD3_k127_2444866_29 DoxX K15977 - - 0.00000000000000000000000000000000000000000000000000000003608 203.0
HFD3_k127_2444866_3 Alcohol dehydrogenase GroES-like domain K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 478.0
HFD3_k127_2444866_30 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000007171 177.0
HFD3_k127_2444866_31 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000000003371 156.0
HFD3_k127_2444866_32 Transglycosylase associated protein - - - 0.0000000000000000000000000000009036 125.0
HFD3_k127_2444866_33 Branched-chain amino acid transport system / permease component K10440 - - 0.000000000000000000000000000002799 134.0
HFD3_k127_2444866_34 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000000000004631 121.0
HFD3_k127_2444866_35 PAP2 superfamily - - - 0.000000000000000000000001056 116.0
HFD3_k127_2444866_36 SnoaL-like domain - - - 0.0000000000000000000002848 109.0
HFD3_k127_2444866_37 SnoaL-like domain - - - 0.0000000000000000000005177 108.0
HFD3_k127_2444866_38 Bacterial lipid A biosynthesis acyltransferase K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.265 0.000000000007917 76.0
HFD3_k127_2444866_39 - - - - 0.0000000004722 64.0
HFD3_k127_2444866_4 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 476.0
HFD3_k127_2444866_40 Methylmuconolactone methyl-isomerase - - - 0.00000000493 66.0
HFD3_k127_2444866_41 SnoaL-like domain - - - 0.000000007639 64.0
HFD3_k127_2444866_42 Methylmuconolactone methyl-isomerase - - - 0.0000002273 58.0
HFD3_k127_2444866_44 - - - - 0.00006916 51.0
HFD3_k127_2444866_45 - - - - 0.0005558 48.0
HFD3_k127_2444866_46 LysE type translocator - - - 0.0006341 44.0
HFD3_k127_2444866_5 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005194 459.0
HFD3_k127_2444866_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K00446 - 1.13.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 461.0
HFD3_k127_2444866_7 import. Responsible for energy coupling to the transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000931 432.0
HFD3_k127_2444866_8 Methionine synthase K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 413.0
HFD3_k127_2444866_9 2-dehydropantoate 2-reductase K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 384.0
HFD3_k127_2445894_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1282.0
HFD3_k127_2445894_1 4-hydroxyphenylacetate 3-hydroxylase N terminal K00483,K21726 - 1.14.13.166,1.14.13.29,1.14.14.9 6.644e-234 751.0
HFD3_k127_2445894_10 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000001951 170.0
HFD3_k127_2445894_11 DUF218 domain - - - 0.000000000000000000000000000000000000000722 163.0
HFD3_k127_2445894_12 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000000001698 128.0
HFD3_k127_2445894_13 Flavin reductase like domain K16048 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006066,GO:0006629,GO:0006694,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008610,GO:0009056,GO:0009058,GO:0016042,GO:0016125,GO:0016127,GO:0016491,GO:0016645,GO:0016646,GO:0036094,GO:0042602,GO:0043167,GO:0043168,GO:0044238,GO:0044281,GO:0044282,GO:0046164,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1902652 - 0.0000000000000000001836 96.0
HFD3_k127_2445894_14 FMN_bind - - - 0.000000000000000017 92.0
HFD3_k127_2445894_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.159e-200 634.0
HFD3_k127_2445894_3 Histidine kinase K07646 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 2.7.13.3 9.393e-195 638.0
HFD3_k127_2445894_4 response regulator, receiver K02483,K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 312.0
HFD3_k127_2445894_5 Ferric reductase like transmembrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000001245 248.0
HFD3_k127_2445894_6 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000005707 217.0
HFD3_k127_2445894_7 protein conserved in bacteria K09966 - - 0.00000000000000000000000000000000000000000000000000003347 194.0
HFD3_k127_2445894_8 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000001531 184.0
HFD3_k127_2445894_9 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000002151 192.0
HFD3_k127_2457414_0 Proline dehydrogenase K13821 - 1.2.1.88,1.5.5.2 0.0 1121.0
HFD3_k127_2457414_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 6.888e-272 846.0
HFD3_k127_2457414_10 unusual protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001918 292.0
HFD3_k127_2457414_11 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000000000000000000000000000000000055 237.0
HFD3_k127_2457414_12 Peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000009293 232.0
HFD3_k127_2457414_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001372 225.0
HFD3_k127_2457414_14 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000005036 188.0
HFD3_k127_2457414_15 Poly(3-hydroxybutyrate) depolymerase K03932 - - 0.000000000000000000000000000000000000003488 161.0
HFD3_k127_2457414_16 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000003366 117.0
HFD3_k127_2457414_17 Transcriptional regulator - - - 0.0000000000000307 76.0
HFD3_k127_2457414_18 ABC-type transport system, involved in lipoprotein release, permease component K02004 - - 0.0000000003454 74.0
HFD3_k127_2457414_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 9.785e-246 764.0
HFD3_k127_2457414_3 DEAD-like helicases superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 538.0
HFD3_k127_2457414_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 521.0
HFD3_k127_2457414_5 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 516.0
HFD3_k127_2457414_6 Belongs to the arginase family K01480 - 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 511.0
HFD3_k127_2457414_7 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 494.0
HFD3_k127_2457414_8 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 365.0
HFD3_k127_2457414_9 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 316.0
HFD3_k127_2457850_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 9.447e-281 874.0
HFD3_k127_2457850_1 AMP-binding enzyme C-terminal domain - - - 5.477e-242 758.0
HFD3_k127_2457850_2 Saccharopine dehydrogenase C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 591.0
HFD3_k127_2457850_3 Divergent 4Fe-4S mono-cluster K05337 - - 0.000000000000000000000008043 106.0
HFD3_k127_2457850_4 nuclease K01174 - 3.1.31.1 0.0000000000000000001659 96.0
HFD3_k127_2470023_0 PFAM transposase, IS4 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000001509 228.0
HFD3_k127_2470023_1 PFAM transposase IS204 IS1001 IS1096 IS1165 family protein - - - 0.00000000000000000000000000000000000000003411 155.0
HFD3_k127_2483449_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 8.372e-228 708.0
HFD3_k127_2483449_1 lipolytic protein G-D-S-L family K01183 - 3.2.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009772 469.0
HFD3_k127_2483449_2 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 419.0
HFD3_k127_2483449_3 lipolytic protein G-D-S-L family K01183 - 3.2.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003491 387.0
HFD3_k127_2483449_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000676 205.0
HFD3_k127_249179_0 5'-nucleotidase, C-terminal domain K01119 - 3.1.3.6,3.1.4.16 0.0 1623.0
HFD3_k127_249179_1 NADH flavin oxidoreductase NADH oxidase K21833 - - 1.668e-256 802.0
HFD3_k127_249179_2 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 585.0
HFD3_k127_249179_3 Metallopeptidase family M24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 574.0
HFD3_k127_249179_4 ABC 3 transport family K09816,K09819 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 314.0
HFD3_k127_249179_5 Zinc-uptake complex component A periplasmic K02077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004966 267.0
HFD3_k127_249179_6 ABC transporter K09817 - - 0.00000000000000000000000000000000000000000000000000000000000000000001738 256.0
HFD3_k127_249179_7 Ferric uptake regulator family K03711 - - 0.0000000000000000000000000000000000005347 144.0
HFD3_k127_2498695_0 PFAM Peptidoglycan-binding LysM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 527.0
HFD3_k127_2498695_1 Type ii secretion system protein e K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 314.0
HFD3_k127_2498695_2 Type ii secretion system - - - 0.00000000000000000000000000000000000000000000000000000000002402 224.0
HFD3_k127_2498695_3 Type II secretion system (T2SS), protein F K12511 - - 0.000000000000000000000000000000000000000000000000000000005127 213.0
HFD3_k127_2498695_7 TadE-like protein - - - 0.00000001376 65.0
HFD3_k127_2502611_0 Non-essential cell division protein that could be required for efficient cell constriction - - - 2.878e-275 871.0
HFD3_k127_2502611_1 PFAM ATPase associated with various cellular activities, AAA_5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 572.0
HFD3_k127_2502611_10 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000000000000003833 164.0
HFD3_k127_2502611_11 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000002037 113.0
HFD3_k127_2502611_12 Nuclease-related domain - - - 0.00009942 49.0
HFD3_k127_2502611_2 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 516.0
HFD3_k127_2502611_3 PFAM zinc finger SWIM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 531.0
HFD3_k127_2502611_4 VWA containing CoxE family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 474.0
HFD3_k127_2502611_5 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K04127,K11325,K21174 - 5.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 422.0
HFD3_k127_2502611_6 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001532 267.0
HFD3_k127_2502611_8 MDMPI C-terminal domain - - - 0.000000000000000000000000000000000000000000000000002446 194.0
HFD3_k127_2502611_9 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000155 173.0
HFD3_k127_2595654_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K17050 - 1.7.5.1,1.8.5.3 0.0 1235.0
HFD3_k127_2595654_1 nitrate reductase beta subunit K00371,K17051 - 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005174 501.0
HFD3_k127_2595654_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 439.0
HFD3_k127_2595654_3 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.00000000000000000000000009078 118.0
HFD3_k127_2595654_4 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.0000000000000000000007461 102.0
HFD3_k127_2595654_5 component of anaerobic - - - 0.0000000000000008348 86.0
HFD3_k127_2595654_6 serine threonine protein kinase - - - 0.0000001469 64.0
HFD3_k127_2599790_0 ABC transporter transmembrane region K06147 - - 1.174e-266 837.0
HFD3_k127_2599790_1 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003994 475.0
HFD3_k127_2599790_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 412.0
HFD3_k127_2599790_3 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 360.0
HFD3_k127_2599790_4 PFAM Class II Aldolase and Adducin N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000008338 202.0
HFD3_k127_2599790_5 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA - - - 0.00000000000000002853 91.0
HFD3_k127_2599790_6 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000009643 71.0
HFD3_k127_2644228_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 6.162e-259 805.0
HFD3_k127_2644228_1 Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 632.0
HFD3_k127_2644228_10 Serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008360,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0040007,GO:0042304,GO:0043085,GO:0043086,GO:0043170,GO:0043388,GO:0043412,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0051055,GO:0051098,GO:0051099,GO:0051101,GO:0051128,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 325.0
HFD3_k127_2644228_11 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007097 317.0
HFD3_k127_2644228_12 Peptidase S9, prolyl oligopeptidase active site domain protein K01322 - 3.4.21.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 303.0
HFD3_k127_2644228_13 Tetrapyrrole (Corrin/Porphyrin) Methylases K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 296.0
HFD3_k127_2644228_15 amino acid activation for nonribosomal peptide biosynthetic process K03641,K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003592 304.0
HFD3_k127_2644228_16 endonuclease activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004042 273.0
HFD3_k127_2644228_17 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000004632 267.0
HFD3_k127_2644228_18 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000000000000000000009394 210.0
HFD3_k127_2644228_19 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000008649 195.0
HFD3_k127_2644228_2 Protein of unknown function (DUF933) K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 566.0
HFD3_k127_2644228_20 PFAM regulatory protein TetR - - - 0.000000000000000000000000000000000000000000000000003171 188.0
HFD3_k127_2644228_21 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.000000000000000000000000000000000000000000000000005116 190.0
HFD3_k127_2644228_22 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000000000000001092 161.0
HFD3_k127_2644228_23 SnoaL-like domain - - - 0.0000000000000000000000000000000008141 134.0
HFD3_k127_2644228_24 bacterial-type flagellum-dependent cell motility - - - 0.00000000000000000000000000000008539 147.0
HFD3_k127_2644228_25 Domain of unknown function (DUF4260) - - - 0.000000000000000000000001148 108.0
HFD3_k127_2644228_26 pyridoxamine 5-phosphate K07005 - - 0.000000000000000000002899 102.0
HFD3_k127_2644228_27 EamA-like transporter family - - - 0.0000000000001277 82.0
HFD3_k127_2644228_28 sequence-specific DNA binding - - - 0.000000000007571 70.0
HFD3_k127_2644228_3 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000451 591.0
HFD3_k127_2644228_30 peptidoglycan-binding domain-containing protein - - - 0.00000003194 64.0
HFD3_k127_2644228_31 peptidoglycan-binding domain-containing protein - - - 0.0000002606 61.0
HFD3_k127_2644228_32 domain protein - - - 0.00004274 59.0
HFD3_k127_2644228_4 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 532.0
HFD3_k127_2644228_5 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 479.0
HFD3_k127_2644228_6 Helix-hairpin-helix domain K04477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 402.0
HFD3_k127_2644228_7 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 389.0
HFD3_k127_2644228_8 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 333.0
HFD3_k127_2644228_9 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 313.0
HFD3_k127_2646623_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0030312,GO:0030350,GO:0032787,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 557.0
HFD3_k127_2646623_1 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 512.0
HFD3_k127_2646623_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006857 444.0
HFD3_k127_2646623_3 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 372.0
HFD3_k127_2646623_5 ABC transporter, ATP-binding protein K16786,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 324.0
HFD3_k127_2646623_6 UTRA K03710 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 292.0
HFD3_k127_2646623_7 Cytochrome oxidase assembly protein K02259 - - 0.000000000000000000000000000000000000000000000000000000007251 211.0
HFD3_k127_2646623_8 BetI-type transcriptional repressor, C-terminal - - - 0.00000000000000000000000000000000000000000024 171.0
HFD3_k127_2646623_9 SnoaL-like domain - - - 0.00000005568 64.0
HFD3_k127_2649279_0 Transposase DDE domain K07492 - - 0.00000000000000000000000000000000002975 145.0
HFD3_k127_2649279_1 Transposase - - - 0.000000000000000000000000002864 115.0
HFD3_k127_2649279_2 23S rRNA-intervening sequence protein - - - 0.000000000000000000007513 96.0
HFD3_k127_2699488_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 5.025e-255 796.0
HFD3_k127_2699488_1 Trehalose utilisation K09992 - - 0.0000000000000000000000000000000000000000000000000334 182.0
HFD3_k127_2706863_0 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 395.0
HFD3_k127_2758472_0 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2336.0
HFD3_k127_2758472_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 7.328e-263 815.0
HFD3_k127_2758472_10 LysM domain - - - 0.000000000000000000392 101.0
HFD3_k127_2758472_2 phosphoribosyltransferase K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005967 518.0
HFD3_k127_2758472_3 DNA ligase N terminus K10747 GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 507.0
HFD3_k127_2758472_4 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 389.0
HFD3_k127_2758472_5 Thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 327.0
HFD3_k127_2758472_6 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 307.0
HFD3_k127_2758472_7 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000054 240.0
HFD3_k127_2758472_8 Putative FMN-binding domain K07734 - - 0.0000000000000000000000000000000000000000000000000000000003671 208.0
HFD3_k127_2758472_9 Belongs to the UPF0502 family K09915 - - 0.0000000000000000000000000000000000000000000002017 174.0
HFD3_k127_2798744_0 Histidine kinase K07653 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005883 351.0
HFD3_k127_2798744_1 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003361 271.0
HFD3_k127_2798744_2 Transcriptional regulatory protein, C terminal K07669,K07672 - - 0.0000000000000000000000000000000000000000000362 162.0
HFD3_k127_2798744_3 Virulence factor BrkB - - - 0.00000000000001394 76.0
HFD3_k127_2815_0 PFAM AMP-dependent synthetase and ligase K00666 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051087 - 0.000000000000000000000000000000000009127 142.0
HFD3_k127_2815_1 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.000000000000000000000000002049 119.0
HFD3_k127_2877711_0 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 4.866e-221 697.0
HFD3_k127_2877711_1 xylulose kinase K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 542.0
HFD3_k127_2877711_10 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000001597 112.0
HFD3_k127_2877711_2 Proline racemase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000546 379.0
HFD3_k127_2877711_3 Telomere recombination K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 327.0
HFD3_k127_2877711_4 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 289.0
HFD3_k127_2877711_5 Cytidylate kinase K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000006814 265.0
HFD3_k127_2877711_6 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008426 262.0
HFD3_k127_2877711_7 FAD dependent oxidoreductase K00285,K03153 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.4.3.19,1.4.5.1 0.00000000000000000000000000000000000000000000000000000000000000000001051 250.0
HFD3_k127_2877711_8 ornithine cyclodeaminase K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000001832 191.0
HFD3_k127_2877711_9 Heat shock protein DnaJ domain protein K05516 - - 0.0000000000000000000000000000000000002933 152.0
HFD3_k127_294265_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0 1774.0
HFD3_k127_294265_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 3.162e-250 782.0
HFD3_k127_294265_10 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 507.0
HFD3_k127_294265_11 ATPases associated with a variety of cellular activities K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 443.0
HFD3_k127_294265_12 Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds K04073 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008774,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 411.0
HFD3_k127_294265_13 Class II Aldolase and Adducin N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 402.0
HFD3_k127_294265_14 Bacterial extracellular solute-binding protein K10232 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 379.0
HFD3_k127_294265_15 Sir2 family K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 354.0
HFD3_k127_294265_16 PFAM pfkB family carbohydrate kinase K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006355 331.0
HFD3_k127_294265_17 binding-protein-dependent transport systems inner membrane component K10234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008541 345.0
HFD3_k127_294265_18 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006551 348.0
HFD3_k127_294265_19 Belongs to the carbamate kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 299.0
HFD3_k127_294265_2 ThiF family - - - 3.001e-205 647.0
HFD3_k127_294265_20 Phosphoenolpyruvate phosphomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002684 285.0
HFD3_k127_294265_21 myo-inosose-2 dehydratase activity K03335 - 4.2.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000175 274.0
HFD3_k127_294265_22 Alternative oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001327 263.0
HFD3_k127_294265_23 Nitronate monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005716 251.0
HFD3_k127_294265_24 Binding-protein-dependent transport system inner membrane component K10233 - - 0.0000000000000000000000000000000000000000000000000000000000000000007626 241.0
HFD3_k127_294265_25 endonuclease activity - - - 0.00000000000000000000000000000000000000000000000000000000007274 220.0
HFD3_k127_294265_27 - - - - 0.0000000000000000000000000000000000000000000000000000009977 200.0
HFD3_k127_294265_28 GDP-mannose mannosyl hydrolase activity K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000003035 191.0
HFD3_k127_294265_29 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000001244 182.0
HFD3_k127_294265_3 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K03520 - 1.2.5.3 7.869e-205 665.0
HFD3_k127_294265_30 nUDIX hydrolase - - - 0.0000000000000000000000000000000000000000000188 170.0
HFD3_k127_294265_31 endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000003398 146.0
HFD3_k127_294265_32 arsenate reductase (glutaredoxin) activity K00537 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.20.4.1 0.000000000000000000000000000000000007866 138.0
HFD3_k127_294265_34 Transglycosylase associated protein - - - 0.0000000000000000000000000000001459 125.0
HFD3_k127_294265_35 Protein of unknown function (DUF4031) - - - 0.0000000000000000000000000000006673 124.0
HFD3_k127_294265_36 Bacterial regulatory proteins, tetR family K22108 GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0042803,GO:0046983,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000172 130.0
HFD3_k127_294265_37 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000001489 100.0
HFD3_k127_294265_38 Rieske 2Fe-2S - - - 0.000000000000000000005146 98.0
HFD3_k127_294265_39 SnoaL-like domain - - - 0.00000000000000000197 97.0
HFD3_k127_294265_4 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 576.0
HFD3_k127_294265_40 F420H(2)-dependent quinone reductase - - - 0.000000000000000002097 89.0
HFD3_k127_294265_41 Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000003157 85.0
HFD3_k127_294265_43 Glucose / Sorbosone dehydrogenase K21430 - - 0.0001693 52.0
HFD3_k127_294265_5 Methionine synthase K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 516.0
HFD3_k127_294265_6 Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds K01666 - 4.1.3.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008794 509.0
HFD3_k127_294265_7 4-hydroxyphenylacetate 3-hydroxylase N terminal K00483,K16901,K21184,K21726 - 1.14.13.166,1.14.13.29,1.14.14.15,1.14.14.8,1.14.14.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005387 503.0
HFD3_k127_294265_8 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 507.0
HFD3_k127_294265_9 CobW/HypB/UreG, nucleotide-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 497.0
HFD3_k127_2965801_0 Histidine kinase - - - 0.0000000000000000000000000000000000004597 156.0
HFD3_k127_300066_0 Fatty acid desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 464.0
HFD3_k127_300066_1 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003981 435.0
HFD3_k127_300066_10 Colicin V production protein - - - 0.000000000000000000000000000002308 133.0
HFD3_k127_300066_11 - - - - 0.000000000000000000000009593 113.0
HFD3_k127_300066_12 Colicin V production protein - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009268,GO:0009405,GO:0009628,GO:0010447,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051704,GO:0071944 - 0.000000000000000001378 94.0
HFD3_k127_300066_2 Extradiol ring-cleavage dioxygenase class III protein subunit B K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 380.0
HFD3_k127_300066_3 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 366.0
HFD3_k127_300066_4 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000156 247.0
HFD3_k127_300066_5 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000001395 190.0
HFD3_k127_300066_6 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000006929 185.0
HFD3_k127_300066_7 Rieske-like [2Fe-2S] domain K05710,K14578,K18248 - - 0.000000000000000000000000000000000000000006782 155.0
HFD3_k127_300066_8 protein histidine kinase activity - - - 0.00000000000000000000000000000000000001313 158.0
HFD3_k127_300066_9 COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM CutM homologs K03519 - 1.2.5.3 0.00000000000000000000000000000000001358 152.0
HFD3_k127_3107685_0 2-oxoglutarate dehydrogenase N-terminus K00164 - 1.2.4.2 0.0 1760.0
HFD3_k127_3107685_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000003706 143.0
HFD3_k127_3107685_2 amine dehydrogenase activity - - - 0.0000007273 59.0
HFD3_k127_3124408_0 Dehydrogenase K00004,K00008 - 1.1.1.14,1.1.1.303,1.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 495.0
HFD3_k127_3124408_1 aldo keto reductase K05275 - 1.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007986 404.0
HFD3_k127_3160568_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01652,K12673 - 2.2.1.6,2.5.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 415.0
HFD3_k127_3160568_1 Aldehyde dehydrogenase family K04072,K15515 - 1.1.1.1,1.2.1.10,1.2.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004376 402.0
HFD3_k127_3160568_10 - - - - 0.0000000000000817 73.0
HFD3_k127_3160568_2 resistance ABC transporter ATPase subunit K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006757 319.0
HFD3_k127_3160568_3 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008172 286.0
HFD3_k127_3160568_4 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005711 256.0
HFD3_k127_3160568_5 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000985 259.0
HFD3_k127_3160568_6 ABC-2 type transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002769 257.0
HFD3_k127_3160568_7 pyridoxamine 5'-phosphate K07005 - - 0.000000000000000000000000000000000000000000000000000000000000000007645 229.0
HFD3_k127_3160568_8 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.00000000000000000000000000000001539 139.0
HFD3_k127_3160568_9 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K19189 - 1.14.13.10 0.00000000000000000000000006811 115.0
HFD3_k127_3161660_0 Acetyl-coenzyme A synthetase N-terminus K01907 - 6.2.1.16 8.448e-244 770.0
HFD3_k127_3161660_1 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 620.0
HFD3_k127_3161660_10 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005066 287.0
HFD3_k127_3161660_11 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007055 292.0
HFD3_k127_3161660_12 Belongs to the pirin family K06911 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002626 278.0
HFD3_k127_3161660_13 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001087 291.0
HFD3_k127_3161660_14 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001733 272.0
HFD3_k127_3161660_15 subfamily IA, variant 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001075 265.0
HFD3_k127_3161660_16 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000003247 244.0
HFD3_k127_3161660_17 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K08234 - - 0.000000000000000000000000000000000000000000000000000000000000000001794 231.0
HFD3_k127_3161660_18 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000004726 209.0
HFD3_k127_3161660_19 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 0.00000000000000000000000000001094 119.0
HFD3_k127_3161660_2 Thiolase, C-terminal domain K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000592 531.0
HFD3_k127_3161660_3 Periplasmic binding protein K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007787 445.0
HFD3_k127_3161660_4 Glycosyl hydrolases family 18 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 376.0
HFD3_k127_3161660_5 alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005335 363.0
HFD3_k127_3161660_6 Coenzyme A transferase K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 330.0
HFD3_k127_3161660_7 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 320.0
HFD3_k127_3161660_8 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 323.0
HFD3_k127_3161660_9 Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004487 314.0
HFD3_k127_3166124_0 Pyridoxal-phosphate dependent enzyme K01505,K05396 - 3.5.99.7,4.4.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 494.0
HFD3_k127_3166124_1 Pfam Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003701 264.0
HFD3_k127_3176651_0 FtsX-like permease family - - - 0.000000000000000000004908 106.0
HFD3_k127_3221037_0 PFAM tRNA synthetases class I (E and Q), catalytic domain K01886 - 6.1.1.18 1.382e-289 903.0
HFD3_k127_3221037_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 3.63e-283 877.0
HFD3_k127_3221037_10 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000936 430.0
HFD3_k127_3221037_11 F420-dependent oxidoreductase, MSMEG_3544 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006258 381.0
HFD3_k127_3221037_12 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005803 346.0
HFD3_k127_3221037_13 Catalyzes the reversible hydration of fumarate to (S)- malate K01676,K01678,K03780 - 4.2.1.2,4.2.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 308.0
HFD3_k127_3221037_14 endonuclease activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005538 258.0
HFD3_k127_3221037_15 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000009784 247.0
HFD3_k127_3221037_16 radical SAM domain protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000263 239.0
HFD3_k127_3221037_17 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000002441 207.0
HFD3_k127_3221037_18 PFAM regulatory protein MarR - - - 0.00000000000000000000000000000000000000000000000000001036 193.0
HFD3_k127_3221037_19 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000005207 189.0
HFD3_k127_3221037_2 ABC transporter - - - 4.096e-240 752.0
HFD3_k127_3221037_20 Haemolysin-III related K11068 - - 0.00000000000000000000000000000000000000000000000257 186.0
HFD3_k127_3221037_21 metal cluster binding K06940 - - 0.0000000000000000000000000000000000000000001184 168.0
HFD3_k127_3221037_22 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000001205 160.0
HFD3_k127_3221037_23 lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.00000000000000000000000000000000000000001437 167.0
HFD3_k127_3221037_24 Peptidase family M23 - - - 0.00000000000000000000000000000000000000002989 167.0
HFD3_k127_3221037_25 transcriptional regulator - - - 0.000000000000000000000001041 109.0
HFD3_k127_3221037_26 Transcriptional regulator - - - 0.000000000000000000009362 101.0
HFD3_k127_3221037_27 Protein of unknown function (DUF2752) - - - 0.000000000000000007267 89.0
HFD3_k127_3221037_28 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000006998 81.0
HFD3_k127_3221037_29 - - - - 0.000000000000007922 87.0
HFD3_k127_3221037_3 glycine radical enzyme, YjjI family - - - 1.335e-223 705.0
HFD3_k127_3221037_30 - - - - 0.00000000000004585 81.0
HFD3_k127_3221037_31 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000001648 63.0
HFD3_k127_3221037_4 Belongs to the DEAD box helicase family K05592,K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 4.382e-220 696.0
HFD3_k127_3221037_5 Belongs to the amidase family K01426 - 3.5.1.4 1.664e-213 674.0
HFD3_k127_3221037_6 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 623.0
HFD3_k127_3221037_7 ABC1 family K03688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 541.0
HFD3_k127_3221037_8 DNA ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 526.0
HFD3_k127_3221037_9 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 464.0
HFD3_k127_3221703_0 Acyl transferase domain - - - 0.0 1348.0
HFD3_k127_3221703_1 Aconitase family (aconitate hydratase) K01681 - 4.2.1.3 0.0 1159.0
HFD3_k127_3221703_10 Oxidoreductase molybdopterin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 466.0
HFD3_k127_3221703_11 Aldo Keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 445.0
HFD3_k127_3221703_12 Bacterial regulatory helix-turn-helix protein, lysR family K04761 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 360.0
HFD3_k127_3221703_13 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 362.0
HFD3_k127_3221703_14 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 346.0
HFD3_k127_3221703_15 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000517 324.0
HFD3_k127_3221703_16 PFAM Fatty acid desaturase, type 2 K03921 - 1.14.19.11,1.14.19.2,1.14.19.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 313.0
HFD3_k127_3221703_17 ABC transporter, ATP-binding protein K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007318 309.0
HFD3_k127_3221703_18 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 299.0
HFD3_k127_3221703_19 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003315 278.0
HFD3_k127_3221703_2 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 4.695e-273 859.0
HFD3_k127_3221703_20 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007266 271.0
HFD3_k127_3221703_21 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002778 251.0
HFD3_k127_3221703_22 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000002525 238.0
HFD3_k127_3221703_23 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000001848 216.0
HFD3_k127_3221703_24 2-hydroxy-3-oxopropionate reductase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000354 203.0
HFD3_k127_3221703_25 transglycosylase - - - 0.000000000000000000000000000000000000000000000002123 186.0
HFD3_k127_3221703_26 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000003449 180.0
HFD3_k127_3221703_27 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000004771 176.0
HFD3_k127_3221703_28 Protein of unknown function (DUF664) - - - 0.00000000000000000000000000000000000000000005645 174.0
HFD3_k127_3221703_29 Bacterial regulatory proteins, tetR family K18939 - - 0.000000000000000000000000000000000000005001 153.0
HFD3_k127_3221703_3 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 1.234e-232 727.0
HFD3_k127_3221703_30 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.000000000000000000000000000000001495 139.0
HFD3_k127_3221703_31 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000001461 120.0
HFD3_k127_3221703_32 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000003871 93.0
HFD3_k127_3221703_33 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.0000008686 56.0
HFD3_k127_3221703_4 acyl-CoA dehydrogenase activity - - - 1.245e-228 724.0
HFD3_k127_3221703_5 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 1.315e-219 687.0
HFD3_k127_3221703_6 HAD-superfamily subfamily IB hydrolase, TIGR01490 K15781 - 2.3.1.51,3.1.3.3 9.015e-198 627.0
HFD3_k127_3221703_7 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 608.0
HFD3_k127_3221703_8 Carboxyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 609.0
HFD3_k127_3221703_9 Alkyl sulfatase dimerisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 550.0
HFD3_k127_3230110_0 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 367.0
HFD3_k127_3230110_1 Peptidase S9, prolyl oligopeptidase active site domain protein K01322 - 3.4.21.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 316.0
HFD3_k127_3230110_2 TAP-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002793 298.0
HFD3_k127_3230110_3 - - - - 0.0000000000000000000000000001235 121.0
HFD3_k127_3230110_4 Anti-sigma-K factor rskA - - - 0.0000000000000000006731 90.0
HFD3_k127_3230110_5 L,D-transpeptidase catalytic domain - - - 0.0000000002777 69.0
HFD3_k127_3230110_6 membrane protein TerC - - - 0.00004116 48.0
HFD3_k127_3235179_0 Methionine synthase K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 526.0
HFD3_k127_3235179_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 400.0
HFD3_k127_3235179_2 Branched-chain amino acid ATP-binding cassette transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 318.0
HFD3_k127_3235179_3 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 289.0
HFD3_k127_3235179_4 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007314 256.0
HFD3_k127_3235179_5 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000471 239.0
HFD3_k127_3235179_6 Phosphotransferase K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000003415 239.0
HFD3_k127_3235179_7 Drug resistance transporter, bcr cfla subfamily K07552 - - 0.0000000000000000000000000000000001933 145.0
HFD3_k127_3235179_8 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000001264 114.0
HFD3_k127_3244152_0 HD domain - - - 7.417e-220 693.0
HFD3_k127_3244152_1 L-lysine 6-monooxygenase (NADPH-requiring) K07222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 530.0
HFD3_k127_3244152_10 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00000000000000000000008067 104.0
HFD3_k127_3244152_12 Dodecin K09165 - - 0.000004154 53.0
HFD3_k127_3244152_2 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 456.0
HFD3_k127_3244152_3 PFAM ROK family K00845,K00886 - 2.7.1.2,2.7.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000002727 263.0
HFD3_k127_3244152_4 OsmC-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000002169 248.0
HFD3_k127_3244152_5 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001461 226.0
HFD3_k127_3244152_6 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000005222 174.0
HFD3_k127_3244152_7 SnoaL-like domain - - - 0.00000000000000000000000000000000001848 139.0
HFD3_k127_3244152_8 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000001041 141.0
HFD3_k127_3244152_9 PFAM Phosphoglycerate mutase K08296 - - 0.000000000000000000000000000000001395 136.0
HFD3_k127_3249101_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1485.0
HFD3_k127_3249101_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1366.0
HFD3_k127_3249101_10 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 569.0
HFD3_k127_3249101_11 Activates fatty acids by binding to coenzyme A K12429,K18662 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051087 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 567.0
HFD3_k127_3249101_12 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 473.0
HFD3_k127_3249101_13 Belongs to the glycosyl hydrolase 13 family K01214,K02438 - 3.2.1.196,3.2.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005629 468.0
HFD3_k127_3249101_14 von Willebrand factor (vWF) type A domain K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 467.0
HFD3_k127_3249101_15 AAA domain (dynein-related subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 439.0
HFD3_k127_3249101_16 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008272,GO:0015698,GO:0016020,GO:0040007,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0072348 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006263 447.0
HFD3_k127_3249101_17 XdhC Rossmann domain K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007217 435.0
HFD3_k127_3249101_18 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 443.0
HFD3_k127_3249101_19 ATPase associated with various cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 423.0
HFD3_k127_3249101_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1249.0
HFD3_k127_3249101_20 Phytanoyl-CoA dioxygenase (PhyH) K00477,K18565 - 1.14.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 403.0
HFD3_k127_3249101_21 Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 407.0
HFD3_k127_3249101_22 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 402.0
HFD3_k127_3249101_23 Belongs to the enoyl-CoA hydratase isomerase family K01692 GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 383.0
HFD3_k127_3249101_24 von Willebrand factor, type A K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 387.0
HFD3_k127_3249101_25 Bacterial extracellular solute-binding protein K02048 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 376.0
HFD3_k127_3249101_26 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 376.0
HFD3_k127_3249101_27 Binding-protein-dependent transport systems inner membrane component K02018,K15496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 355.0
HFD3_k127_3249101_28 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006962 355.0
HFD3_k127_3249101_29 mandelate racemase muconate lactonizing - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004694 340.0
HFD3_k127_3249101_3 Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit K00124 - - 3.36e-250 790.0
HFD3_k127_3249101_30 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 327.0
HFD3_k127_3249101_31 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 327.0
HFD3_k127_3249101_32 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007161 325.0
HFD3_k127_3249101_33 XdhC and CoxI family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004632 302.0
HFD3_k127_3249101_34 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 296.0
HFD3_k127_3249101_35 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 305.0
HFD3_k127_3249101_36 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007484 291.0
HFD3_k127_3249101_37 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001383 278.0
HFD3_k127_3249101_38 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001663 274.0
HFD3_k127_3249101_39 Protein of unknown function (DUF459) K09795 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005861 271.0
HFD3_k127_3249101_4 acyl-CoA dehydrogenase - - - 3.678e-224 699.0
HFD3_k127_3249101_40 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000005883 263.0
HFD3_k127_3249101_41 - K08641 - 3.4.13.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000001208 271.0
HFD3_k127_3249101_42 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000008109 261.0
HFD3_k127_3249101_43 Phosphoesterase, PA-phosphatase related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004527 263.0
HFD3_k127_3249101_44 PaaX-like protein K02616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001604 266.0
HFD3_k127_3249101_45 Carbon monoxide dehydrogenase subunit G (CoxG) K09386 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004977 245.0
HFD3_k127_3249101_46 2Fe-2S -binding K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000001065 236.0
HFD3_k127_3249101_47 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000004379 236.0
HFD3_k127_3249101_48 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000001631 214.0
HFD3_k127_3249101_49 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000007525 197.0
HFD3_k127_3249101_5 Peptidase family M1 domain K08776 - - 5.575e-218 704.0
HFD3_k127_3249101_50 XdhC and CoxI family - - - 0.000000000000000000000000000000000000000000000003294 175.0
HFD3_k127_3249101_51 Protein of unknown function (DUF501) K09009 - - 0.0000000000000000000000000000000000000000000004791 176.0
HFD3_k127_3249101_52 Iron permease FTR1 K07243 - - 0.000000000000000000000000000000000000000008619 164.0
HFD3_k127_3249101_53 MobA-like NTP transferase domain K07141,K19190 - 1.1.1.328,2.7.7.76 0.00000000000000000000000000000000000000001857 160.0
HFD3_k127_3249101_54 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000001216 156.0
HFD3_k127_3249101_55 cysteine-type peptidase activity K21471 - - 0.00000000000000000000000000000000002737 143.0
HFD3_k127_3249101_56 universal stress protein - - - 0.00000000000000000000000000000000007924 148.0
HFD3_k127_3249101_57 helix_turn_helix ASNC type K03718 - - 0.0000000000000000000000000000000001673 139.0
HFD3_k127_3249101_58 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.000000000000000000000000000002209 127.0
HFD3_k127_3249101_6 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666 - - 1.717e-210 668.0
HFD3_k127_3249101_60 Serine aminopeptidase, S33 K16050 - 3.7.1.17 0.0000000000000000003641 102.0
HFD3_k127_3249101_61 Ppx/GppA phosphatase family - - - 0.000000000000000002432 91.0
HFD3_k127_3249101_62 Putative adhesin - - - 0.00000000000000006981 90.0
HFD3_k127_3249101_63 Stress responsive A/B Barrel Domain - - - 0.0000000000000002557 82.0
HFD3_k127_3249101_64 Protein conserved in bacteria - - - 0.0000000000001341 77.0
HFD3_k127_3249101_65 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000001892 74.0
HFD3_k127_3249101_66 protein encoded in hypervariable junctions of pilus gene clusters - - - 0.000000006103 63.0
HFD3_k127_3249101_67 4-Hydroxyphenylpyruvate dioxygenase K05606,K17315 - 5.1.99.1 0.000006315 55.0
HFD3_k127_3249101_68 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768,K09565 - 5.2.1.8 0.00001359 57.0
HFD3_k127_3249101_69 Psort location Cytoplasmic, score - - - 0.0001038 54.0
HFD3_k127_3249101_7 phosphoglucomutase phosphomannomutase alpha beta alpha domain II K01835,K01840 - 5.4.2.2,5.4.2.8 1.264e-201 645.0
HFD3_k127_3249101_8 ABC transporter K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 610.0
HFD3_k127_3249101_9 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 596.0
HFD3_k127_3267164_0 FAD dependent oxidoreductase central domain - - - 0.0 1315.0
HFD3_k127_3267164_1 ATPase P-type (Transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1019.0
HFD3_k127_3267164_10 Ftsk_gamma K03466 - - 1.701e-208 674.0
HFD3_k127_3267164_11 Pfam Sulfatase - - - 4.11e-208 680.0
HFD3_k127_3267164_12 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K14441 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0035596,GO:0035599,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 612.0
HFD3_k127_3267164_13 Rieske 2Fe-2S K00479 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 557.0
HFD3_k127_3267164_14 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007335 541.0
HFD3_k127_3267164_15 Serine hydroxymethyltransferase K00600,K18847 - 2.1.2.1,2.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007001 535.0
HFD3_k127_3267164_16 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 517.0
HFD3_k127_3267164_17 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 505.0
HFD3_k127_3267164_18 Competence-damaged protein K03742 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 504.0
HFD3_k127_3267164_19 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 497.0
HFD3_k127_3267164_2 Protein synonym hydantoin utilization protein A K01473 - 3.5.2.14 0.0 1013.0
HFD3_k127_3267164_20 Belongs to the arginase family K12255 - 3.5.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004529 479.0
HFD3_k127_3267164_21 glutamine synthetase K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005127 467.0
HFD3_k127_3267164_22 Aldehyde dehydrogenase family K22187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 458.0
HFD3_k127_3267164_23 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 442.0
HFD3_k127_3267164_24 Oligopeptide/dipeptide transporter, C-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 438.0
HFD3_k127_3267164_25 Acetamidase/Formamidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 440.0
HFD3_k127_3267164_26 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 442.0
HFD3_k127_3267164_27 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 432.0
HFD3_k127_3267164_28 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 422.0
HFD3_k127_3267164_29 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005813 401.0
HFD3_k127_3267164_3 Bacterial transcriptional activator domain - - - 1.476e-283 906.0
HFD3_k127_3267164_30 Iron-containing redox enzyme K06137 - 1.3.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008011 393.0
HFD3_k127_3267164_31 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006557 397.0
HFD3_k127_3267164_32 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 400.0
HFD3_k127_3267164_33 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007688 405.0
HFD3_k127_3267164_34 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 387.0
HFD3_k127_3267164_35 FAD dependent oxidoreductase K19746 - 1.4.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 386.0
HFD3_k127_3267164_36 decarboxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005531 387.0
HFD3_k127_3267164_37 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 355.0
HFD3_k127_3267164_38 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006605 329.0
HFD3_k127_3267164_39 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 322.0
HFD3_k127_3267164_4 Zn-dependent metallo-hydrolase RNA specificity domain K12574 - - 5.765e-271 842.0
HFD3_k127_3267164_40 Beta-eliminating lyase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 322.0
HFD3_k127_3267164_41 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 322.0
HFD3_k127_3267164_42 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006202 325.0
HFD3_k127_3267164_43 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 322.0
HFD3_k127_3267164_44 CarD-like/TRCF domain K07736 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003804 299.0
HFD3_k127_3267164_45 PFAM Methionine synthase, vitamin-B12 independent K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009976 308.0
HFD3_k127_3267164_46 COG0657 Esterase lipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007431 294.0
HFD3_k127_3267164_47 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 297.0
HFD3_k127_3267164_48 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002276 288.0
HFD3_k127_3267164_49 Binding-protein-dependent transport system inner membrane component K02038 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004049 278.0
HFD3_k127_3267164_5 Protein synonym hydantoin utilization protein B K01474 - 3.5.2.14 9.81e-271 860.0
HFD3_k127_3267164_50 4-hydroxy-tetrahydrodipicolinate reductase K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003943 280.0
HFD3_k127_3267164_51 HD phosphohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001216 269.0
HFD3_k127_3267164_52 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002991 273.0
HFD3_k127_3267164_53 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004039 277.0
HFD3_k127_3267164_54 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.00000000000000000000000000000000000000000000000000000000000000000000000508 253.0
HFD3_k127_3267164_55 Inosine-uridine preferring nucleoside hydrolase K01240 - 3.2.2.3 0.000000000000000000000000000000000000000000000000000000000000000000001257 251.0
HFD3_k127_3267164_56 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000006817 240.0
HFD3_k127_3267164_57 A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics - - - 0.000000000000000000000000000000000000000000000000000000000000000001622 247.0
HFD3_k127_3267164_58 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000009787 233.0
HFD3_k127_3267164_59 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000005801 201.0
HFD3_k127_3267164_6 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins - - - 1.209e-236 756.0
HFD3_k127_3267164_60 Transcriptional regulator K05799 - - 0.00000000000000000000000000000000000000000000000000000001062 212.0
HFD3_k127_3267164_61 Methyltransferase type 12 - - - 0.00000000000000000000000000000000000000000000000000000002865 202.0
HFD3_k127_3267164_62 MerR, DNA binding K13639 - - 0.00000000000000000000000000000000000000000000000000000006399 198.0
HFD3_k127_3267164_63 PFAM Methionine sulfoxide reductase B K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000002217 199.0
HFD3_k127_3267164_64 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000005161 203.0
HFD3_k127_3267164_65 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000005355 183.0
HFD3_k127_3267164_66 FCD - - - 0.0000000000000000000000000000000000000000000002298 175.0
HFD3_k127_3267164_67 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000005688 172.0
HFD3_k127_3267164_68 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000004429 181.0
HFD3_k127_3267164_69 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000002669 160.0
HFD3_k127_3267164_7 Glucose inhibited division protein A - - - 9.544e-234 730.0
HFD3_k127_3267164_70 Haem-degrading - - - 0.00000000000000000000000000000000000000001161 164.0
HFD3_k127_3267164_71 Dehydrogenase reductase sdr K00059 - 1.1.1.100 0.00000000000000000000000000000000000000002115 167.0
HFD3_k127_3267164_72 F420H(2)-dependent quinone reductase - - - 0.00000000000000000000000000000000000000002228 169.0
HFD3_k127_3267164_73 ornithine cyclodeaminase K01750 - 4.3.1.12 0.0000000000000000000000000000000000000008675 166.0
HFD3_k127_3267164_74 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000000000000000000000000000008833 153.0
HFD3_k127_3267164_75 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.0000000000000000000000000000000000003098 157.0
HFD3_k127_3267164_76 SnoaL-like domain - - - 0.0000000000000000000000000000000000005209 152.0
HFD3_k127_3267164_77 homocysteine S-methyltransferase K00547 - 2.1.1.10 0.00000000000000000000000000000000001225 149.0
HFD3_k127_3267164_78 COG0666 FOG Ankyrin repeat - - - 0.00000000000000000000000000000001699 139.0
HFD3_k127_3267164_79 Anti-sigma-K factor rskA - - - 0.00000000000000000000000000000187 130.0
HFD3_k127_3267164_8 Rieske [2Fe-2S] domain K15762 - - 9.539e-214 677.0
HFD3_k127_3267164_80 peroxiredoxin activity K03386,K03564 - 1.11.1.15 0.0000000000000000000000000008392 115.0
HFD3_k127_3267164_81 acyl-L-homoserine-lactone lactonohydrolase activity K13075 - 3.1.1.81 0.000000000000000000000000002988 121.0
HFD3_k127_3267164_82 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000278 108.0
HFD3_k127_3267164_83 Rieske-like [2Fe-2S] domain K00363 - 1.7.1.15 0.000000000000000000000004033 113.0
HFD3_k127_3267164_84 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.0000000000000000000001859 113.0
HFD3_k127_3267164_86 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000004126 101.0
HFD3_k127_3267164_87 NlpC/P60 family K21471,K21473 - - 0.000000000000000003193 97.0
HFD3_k127_3267164_88 Major Facilitator K18567,K19577 - - 0.000000000001123 81.0
HFD3_k127_3267164_89 bacterioferritin comigratory protein K03564 - 1.11.1.15 0.000000000002437 67.0
HFD3_k127_3267164_9 PFAM AMP-dependent synthetase and ligase K02182 - 6.2.1.48 2.498e-210 681.0
HFD3_k127_3267164_90 Endonuclease/Exonuclease/phosphatase family - - - 0.0000001374 64.0
HFD3_k127_3267164_91 - - - - 0.000002609 59.0
HFD3_k127_3267164_92 protein ubiquitination - - - 0.00001035 57.0
HFD3_k127_3283768_0 PFAM Type II secretion system protein E K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 539.0
HFD3_k127_3283768_1 COG1404 Subtilisin-like serine proteases K14645 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 408.0
HFD3_k127_3283768_10 - - - - 0.0000000000000000000002297 109.0
HFD3_k127_3283768_11 Peptidase A24A, prepilin type IV K02654 - 3.4.23.43 0.0000000000000000002065 95.0
HFD3_k127_3283768_12 PAS domain K18350 - 2.7.13.3 0.0000000000001631 79.0
HFD3_k127_3283768_13 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000000219 78.0
HFD3_k127_3283768_14 lactoylglutathione lyase activity - - - 0.00008576 51.0
HFD3_k127_3283768_2 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 392.0
HFD3_k127_3283768_3 COG3209 Rhs family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001015 277.0
HFD3_k127_3283768_4 Type II secretion system (T2SS), protein F K12510 - - 0.00000000000000000000000000000000000000000000000000000003348 217.0
HFD3_k127_3283768_5 Evidence 2b Function of strongly homologous gene K02282 - - 0.0000000000000000000000000000000000000000000000000003803 200.0
HFD3_k127_3283768_6 methyltransferase activity - - - 0.00000000000000000000000000000000000000000000002853 186.0
HFD3_k127_3283768_7 Type ii secretion system K12511 - - 0.00000000000000000000000000000000000000000004864 172.0
HFD3_k127_3283768_8 Pilus assembly protein K02279 - - 0.0000000000000000000000000005176 126.0
HFD3_k127_3283768_9 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000611 108.0
HFD3_k127_3301086_0 transferase activity, transferring acyl groups other than amino-acyl groups K13687 GO:0008150,GO:0040007 - 8.402e-223 741.0
HFD3_k127_3301086_1 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 301.0
HFD3_k127_3301086_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 301.0
HFD3_k127_3301086_3 lipolytic protein G-D-S-L family - - - 0.0000000000002072 74.0
HFD3_k127_3318762_0 mandelate racemase muconate lactonizing K18334 - 4.2.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003912 587.0
HFD3_k127_3318762_1 luxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 533.0
HFD3_k127_3318762_2 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 347.0
HFD3_k127_3318762_3 amidohydrolase K07046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 302.0
HFD3_k127_3318762_4 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001268 279.0
HFD3_k127_3318762_5 Protein of unknown function (DUF1003) - - - 0.00000000000000000000000000000000000000000000000000369 188.0
HFD3_k127_3318762_6 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000000000000000000000000000000001625 194.0
HFD3_k127_3318762_7 Periplasmic binding protein domain K10439 - - 0.00000000000000000000000000000000000000000001207 164.0
HFD3_k127_3318762_8 - - - - 0.000000000003747 75.0
HFD3_k127_3405185_0 C-terminal, D2-small domain, of ClpB protein K03696 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944 - 0.0 1330.0
HFD3_k127_3405185_1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 1.817e-303 949.0
HFD3_k127_3405185_10 Cytochrome b(C-terminal)/b6/petD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 382.0
HFD3_k127_3405185_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 371.0
HFD3_k127_3405185_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007905 334.0
HFD3_k127_3405185_13 oxidoreductase activity, acting on diphenols and related substances as donors K02636,K03886 - 1.10.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 304.0
HFD3_k127_3405185_14 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004231 294.0
HFD3_k127_3405185_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001242 274.0
HFD3_k127_3405185_16 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003316 258.0
HFD3_k127_3405185_17 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000008299 244.0
HFD3_k127_3405185_18 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000005329 226.0
HFD3_k127_3405185_19 - - - - 0.00000000000000000000000000000000000000000000000000000000000005496 217.0
HFD3_k127_3405185_2 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 1.941e-251 783.0
HFD3_k127_3405185_20 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000004531 214.0
HFD3_k127_3405185_21 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000008442 178.0
HFD3_k127_3405185_22 amine dehydrogenase activity - - - 0.00000000000000000000000000000000001287 153.0
HFD3_k127_3405185_23 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000003573 136.0
HFD3_k127_3405185_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 3.158e-242 759.0
HFD3_k127_3405185_4 FAD binding domain K21401 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016491,GO:0016627,GO:0030312,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 1.3.99.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 565.0
HFD3_k127_3405185_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 526.0
HFD3_k127_3405185_6 Cytochrome b/b6/petB K03891 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 479.0
HFD3_k127_3405185_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000885 446.0
HFD3_k127_3405185_8 Polyprenyl synthetase K00805 - 2.5.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 428.0
HFD3_k127_3405185_9 protein synonym multiple resistance and pH homeostasis protein A K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008459 395.0
HFD3_k127_3416120_0 domain protein K13735 - - 0.00001533 58.0
HFD3_k127_3417633_0 ANTAR domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000006547 225.0
HFD3_k127_3417633_1 ANTAR - - - 0.00000000000000000000000000000000000000001143 163.0
HFD3_k127_3417633_2 - - - - 0.0000000000000000000000000000000000002147 150.0
HFD3_k127_3426714_0 Branched-chain amino acid transport system / permease component K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003166 409.0
HFD3_k127_3426714_1 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 348.0
HFD3_k127_3426714_2 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006478 352.0
HFD3_k127_3426714_3 gntR family K05799 - - 0.00000000000000000000000000000000000000000000000000000000000000000003915 239.0
HFD3_k127_3426714_4 Periplasmic binding protein domain K10439 - - 0.00000000000000000000000000000000000915 143.0
HFD3_k127_3443577_0 AMP-forming long-chain acyl-CoA synthetase K01897 - 6.2.1.3 9.74e-245 775.0
HFD3_k127_3443577_1 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 610.0
HFD3_k127_3443577_10 Periplasmic binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003227 248.0
HFD3_k127_3443577_11 Beta-lactamase K01286 - 3.4.16.4 0.00000000000000000000000000000000000000004692 171.0
HFD3_k127_3443577_15 lactoylglutathione lyase activity - - - 0.000000001542 61.0
HFD3_k127_3443577_2 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 605.0
HFD3_k127_3443577_3 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 441.0
HFD3_k127_3443577_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 407.0
HFD3_k127_3443577_5 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 368.0
HFD3_k127_3443577_6 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 362.0
HFD3_k127_3443577_7 pfam abc K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007744 339.0
HFD3_k127_3443577_8 PFAM Bacterial regulatory protein, arsR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 308.0
HFD3_k127_3443577_9 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 293.0
HFD3_k127_3447225_0 deiminase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 463.0
HFD3_k127_3447225_1 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000004183 246.0
HFD3_k127_3447225_2 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.000000005973 57.0
HFD3_k127_3451405_0 PFAM glycoside hydrolase family 77 K00705 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.4.1.25 8.604e-266 836.0
HFD3_k127_3451405_1 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 591.0
HFD3_k127_3451405_10 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 342.0
HFD3_k127_3451405_11 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000205 280.0
HFD3_k127_3451405_12 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001246 249.0
HFD3_k127_3451405_13 GHMP kinases N terminal domain K00872 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000378 245.0
HFD3_k127_3451405_14 RNA-binding protein containing a PIN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001021 256.0
HFD3_k127_3451405_15 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000005637 235.0
HFD3_k127_3451405_16 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000000000000000000000000000000007236 209.0
HFD3_k127_3451405_17 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000001238 209.0
HFD3_k127_3451405_18 BetI-type transcriptional repressor, C-terminal - - - 0.0000000000000000000000000000000000000000000000000004668 191.0
HFD3_k127_3451405_19 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000007544 190.0
HFD3_k127_3451405_2 EXOIII K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 582.0
HFD3_k127_3451405_20 dehydratase - - - 0.000000000000000000000000000000000000000000000000001287 190.0
HFD3_k127_3451405_21 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000002482 197.0
HFD3_k127_3451405_22 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000004008 207.0
HFD3_k127_3451405_23 endonuclease activity - - - 0.00000000000000000000000000000000002709 142.0
HFD3_k127_3451405_24 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000781 135.0
HFD3_k127_3451405_25 Ferric uptake regulator family K22297 - - 0.0000000000000000000000000000004949 127.0
HFD3_k127_3451405_26 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000002033 121.0
HFD3_k127_3451405_28 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18955 - - 0.00000000000000000000000001296 113.0
HFD3_k127_3451405_3 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005754 554.0
HFD3_k127_3451405_31 endonuclease activity - - - 0.000000000000005938 85.0
HFD3_k127_3451405_32 - - - - 0.000002145 53.0
HFD3_k127_3451405_4 Male sterility protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 514.0
HFD3_k127_3451405_5 Acyl-CoA dehydrogenase, C-terminal domain K00248,K14448 - 1.3.8.1,1.3.8.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005039 516.0
HFD3_k127_3451405_6 Cysteine-rich domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 480.0
HFD3_k127_3451405_7 FAD linked K00803 - 2.5.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003753 479.0
HFD3_k127_3451405_8 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004828 409.0
HFD3_k127_3451405_9 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007832 367.0
HFD3_k127_3457262_0 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005418 516.0
HFD3_k127_3457262_1 Catalyzes the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004153 345.0
HFD3_k127_3457262_2 Histidine kinase K07682 GO:0000166,GO:0000287,GO:0001666,GO:0003032,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009593,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0019826,GO:0020037,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042165,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0051606,GO:0051775,GO:0051776,GO:0070025,GO:0070026,GO:0070482,GO:0070483,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 0.0000000000000000000000000000000000000000000000000001762 204.0
HFD3_k127_3457262_3 amine dehydrogenase activity K01077,K07004,K21449 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 3.1.3.1 0.0000000000000000000000000000000000483 147.0
HFD3_k127_3503108_0 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.00000000000000000000000000000000001562 152.0
HFD3_k127_3503108_1 WD40-like Beta Propeller Repeat - - - 0.0000000000003925 82.0
HFD3_k127_3503108_2 Carboxylesterase family - - - 0.00000000002216 75.0
HFD3_k127_3540046_0 transmembrane transporter activity K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 301.0
HFD3_k127_3549315_0 ABC transporter transmembrane region K06147 - - 2.577e-243 793.0
HFD3_k127_3549315_1 ABC transporter transmembrane region K06147 - - 6.725e-242 760.0
HFD3_k127_3549315_10 molybdenum ion binding K07140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004567 269.0
HFD3_k127_3549315_11 Activator of Hsp90 ATPase 1 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006275 247.0
HFD3_k127_3549315_12 dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000000000000000000000000000000000000000006537 237.0
HFD3_k127_3549315_13 alpha-ribazole phosphatase activity K02226,K15634,K22305,K22306,K22316 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.3,3.1.3.73,3.1.3.85,5.4.2.12 0.00000000000000000000000000000000000000000000000000478 186.0
HFD3_k127_3549315_14 arsR family - - - 0.00000000000000000000000000000000000000000000251 168.0
HFD3_k127_3549315_15 transcriptional regulator - - - 0.0000000000000000000000000000000000000000002273 165.0
HFD3_k127_3549315_16 - - - - 0.0000000000000000000000000000000000000000008985 161.0
HFD3_k127_3549315_17 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000371 161.0
HFD3_k127_3549315_18 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000004055 153.0
HFD3_k127_3549315_19 - - - - 0.00000000000000000000000000000000002774 139.0
HFD3_k127_3549315_2 penicillin-binding protein - - - 1.242e-235 751.0
HFD3_k127_3549315_20 - K07164,K22391 - 3.5.4.16 0.0000000000000000000000002098 114.0
HFD3_k127_3549315_21 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000006187 100.0
HFD3_k127_3549315_22 Protein of unknown function (DUF1326) - - - 0.000000000000000003374 93.0
HFD3_k127_3549315_23 4-alpha-glucanotransferase K00705 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.4.1.25 0.000000000000008188 78.0
HFD3_k127_3549315_24 STAS domain K06378 - - 0.000000000006848 71.0
HFD3_k127_3549315_25 STAS domain K04749 - - 0.0000000001178 68.0
HFD3_k127_3549315_26 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.00000001642 58.0
HFD3_k127_3549315_27 protein secretion K03116 - - 0.00000005311 56.0
HFD3_k127_3549315_28 STAS domain - - - 0.0009721 46.0
HFD3_k127_3549315_3 involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 470.0
HFD3_k127_3549315_4 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009849 439.0
HFD3_k127_3549315_5 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 398.0
HFD3_k127_3549315_6 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 383.0
HFD3_k127_3549315_7 Glycosyltransferase family 20 K00697,K16055 - 2.4.1.15,2.4.1.347,3.1.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 394.0
HFD3_k127_3549315_8 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 290.0
HFD3_k127_3549315_9 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005234 283.0
HFD3_k127_3667662_0 AMP-binding enzyme C-terminal domain K00666 - - 2.84e-213 671.0
HFD3_k127_3667662_1 Xaa-Pro aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 509.0
HFD3_k127_3667662_2 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 473.0
HFD3_k127_3779985_0 transcriptional regulator - - - 0.0 1111.0
HFD3_k127_3779985_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 1.454e-208 664.0
HFD3_k127_3779985_2 PFAM ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005193 276.0
HFD3_k127_3779985_3 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000001221 248.0
HFD3_k127_3779985_4 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000008377 226.0
HFD3_k127_3779985_5 Golgi phosphoprotein 3 (GPP34) - - - 0.0000000000000000000000000000000000000000000000000000002739 202.0
HFD3_k127_3790860_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1091.0
HFD3_k127_3790860_1 Phosphoribosylglycinamide synthetase, C domain K01945,K11788 - 6.3.3.1,6.3.4.13 5.407e-297 937.0
HFD3_k127_3790860_10 Domain of unknown function (DUF4262) - - - 0.000000000000000000000000000000000000000000000000000000000000000000007961 239.0
HFD3_k127_3790860_11 Histidine phosphatase superfamily (branch 1) K15634 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000002506 227.0
HFD3_k127_3790860_12 SURF1-like protein - GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944 - 0.000000000000000000000000000000000000000000000000003799 191.0
HFD3_k127_3790860_2 VWA domain containing CoxE-like protein K07161 - - 6.805e-265 820.0
HFD3_k127_3790860_3 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 8.966e-251 781.0
HFD3_k127_3790860_4 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 3.842e-238 751.0
HFD3_k127_3790860_5 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 552.0
HFD3_k127_3790860_6 AAA domain (dynein-related subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004934 464.0
HFD3_k127_3790860_7 SAICAR synthetase K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 359.0
HFD3_k127_3790860_8 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 301.0
HFD3_k127_3790860_9 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000007924 244.0
HFD3_k127_3854638_0 WD40 repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000002628 260.0
HFD3_k127_3854638_1 ABC transporter, substratebinding protein K10232 - - 0.000000000000000000000000000000000000000001813 180.0
HFD3_k127_3854638_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000009195 132.0
HFD3_k127_3854638_3 Tetratricopeptide repeat - - - 0.0000000009143 70.0
HFD3_k127_3883012_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688,K18786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.321 0.0 3087.0
HFD3_k127_3883012_1 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 9.77e-208 653.0
HFD3_k127_3883012_10 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002133 258.0
HFD3_k127_3883012_11 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001999 249.0
HFD3_k127_3883012_12 sequence-specific DNA binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000172 242.0
HFD3_k127_3883012_13 transcriptional regulator K03566 - - 0.0000000000000000000000000000000000000000000000000000000000000000008187 237.0
HFD3_k127_3883012_14 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000009382 240.0
HFD3_k127_3883012_15 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000204 224.0
HFD3_k127_3883012_16 Nuclease-related domain - - - 0.00000000000000000000000000000000000000000000000000000000000004535 220.0
HFD3_k127_3883012_17 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000000000000002232 211.0
HFD3_k127_3883012_18 - - - - 0.0000000000000000000000000000000000000000000000002401 184.0
HFD3_k127_3883012_19 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000001338 173.0
HFD3_k127_3883012_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 526.0
HFD3_k127_3883012_20 CGNR zinc finger - - - 0.000000000000000000000000000000271 130.0
HFD3_k127_3883012_21 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000008606 115.0
HFD3_k127_3883012_22 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000224 100.0
HFD3_k127_3883012_23 GYD domain - - - 0.000000008705 63.0
HFD3_k127_3883012_24 pyridoxamine 5-phosphate - - - 0.0002382 50.0
HFD3_k127_3883012_3 Peptidase family S41 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 515.0
HFD3_k127_3883012_4 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 440.0
HFD3_k127_3883012_5 Trypsin-like serine protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004587 424.0
HFD3_k127_3883012_6 Ornithine cyclodeaminase/mu-crystallin family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 397.0
HFD3_k127_3883012_7 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006444 356.0
HFD3_k127_3883012_8 Pfam:Pyridox_oxidase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005459 337.0
HFD3_k127_3883012_9 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000652 323.0
HFD3_k127_3917320_0 phosphoenolpyruvate carboxykinase (ATP) activity K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 2.265e-212 674.0
HFD3_k127_3917320_10 Phosphotransferase enzyme family - - - 0.000000000000000000117 100.0
HFD3_k127_3917320_11 - - - - 0.000000000005079 68.0
HFD3_k127_3917320_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009712 508.0
HFD3_k127_3917320_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 446.0
HFD3_k127_3917320_4 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 340.0
HFD3_k127_3917320_5 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 303.0
HFD3_k127_3917320_6 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004436 297.0
HFD3_k127_3917320_7 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000004297 239.0
HFD3_k127_3917320_8 - - - - 0.00000000000000000000000000000000000000000000000001296 183.0
HFD3_k127_3917320_9 desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000003362 138.0
HFD3_k127_3925408_0 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 373.0
HFD3_k127_3925408_1 dipeptide transport K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 345.0
HFD3_k127_3925408_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 319.0
HFD3_k127_3925408_3 Belongs to the GcvT family K00302 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000001248 271.0
HFD3_k127_3925408_4 endonuclease activity - - - 0.000000000000000000000000000000000000000000000000000000008805 214.0
HFD3_k127_3925408_5 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.00000000000000000000000000001943 126.0
HFD3_k127_3925408_6 Sarcosine oxidase, delta subunit family K00304 - 1.5.3.1 0.00000000005505 75.0
HFD3_k127_39278_0 elongation factor Tu domain 2 protein K02355 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944 - 8.458e-288 899.0
HFD3_k127_39278_1 AAA domain K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 455.0
HFD3_k127_39278_11 DSBA-like thioredoxin domain - - - 0.000000009192 57.0
HFD3_k127_39278_2 AMP-binding enzyme C-terminal domain K01911 - 6.2.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 400.0
HFD3_k127_39278_3 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain K21023 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 384.0
HFD3_k127_39278_4 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 349.0
HFD3_k127_39278_5 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006247 325.0
HFD3_k127_39278_6 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007604 319.0
HFD3_k127_39278_7 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001115 273.0
HFD3_k127_39278_8 alpha/beta hydrolase fold K08680 - 4.2.99.20 0.000000000000000000000000000000000000000000000000000000000001634 220.0
HFD3_k127_39278_9 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000000000000000000001124 188.0
HFD3_k127_3932991_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 314.0
HFD3_k127_3935780_0 Voltage gated chloride channel K03281 - - 0.000000000005271 78.0
HFD3_k127_3985720_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007081 517.0
HFD3_k127_3985720_1 PFAM ABC transporter related K01990,K19340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 337.0
HFD3_k127_3985720_10 NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.00000000000000000000000000000000000000000000000003408 194.0
HFD3_k127_3985720_11 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000008955 198.0
HFD3_k127_3985720_12 Binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000000000007344 170.0
HFD3_k127_3985720_13 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000000000000005649 165.0
HFD3_k127_3985720_14 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000001029 164.0
HFD3_k127_3985720_15 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000000000003841 134.0
HFD3_k127_3985720_16 Cache domain - - - 0.0000000000000000000000000002391 122.0
HFD3_k127_3985720_18 CsbD-like - - - 0.0000000004745 62.0
HFD3_k127_3985720_19 PspC domain - - - 0.000000001654 70.0
HFD3_k127_3985720_2 May catalyze the transamination reaction in phenylalanine biosynthesis K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 313.0
HFD3_k127_3985720_3 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 301.0
HFD3_k127_3985720_4 Response regulator receiver domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009445 260.0
HFD3_k127_3985720_5 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002006 247.0
HFD3_k127_3985720_6 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008614 252.0
HFD3_k127_3985720_7 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000002814 246.0
HFD3_k127_3985720_8 Single-strand binding protein family K03111 - - 0.00000000000000000000000000000000000000000000000000000000001022 210.0
HFD3_k127_3985720_9 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000122 188.0
HFD3_k127_4011858_0 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 5.221e-218 681.0
HFD3_k127_4011858_1 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 2.258e-205 653.0
HFD3_k127_4011858_2 o-methyltransferase K21377 - 2.1.1.302 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 509.0
HFD3_k127_4011858_3 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007411 518.0
HFD3_k127_4011858_4 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 418.0
HFD3_k127_4011858_5 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 407.0
HFD3_k127_4011858_6 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 357.0
HFD3_k127_4011858_7 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005644 248.0
HFD3_k127_4011858_8 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000001 202.0
HFD3_k127_4012219_0 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 1.418e-297 930.0
HFD3_k127_4012219_1 Nitrate reductase delta subunit - - - 0.000000000002706 79.0
HFD3_k127_4034611_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 510.0
HFD3_k127_4034611_1 P-aminobenzoate N-oxygenase AurF - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 509.0
HFD3_k127_4034611_10 with chaperone activity, ATP-binding subunit K03696 - - 0.000000000000000000000000000002703 125.0
HFD3_k127_4034611_11 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000009755 93.0
HFD3_k127_4034611_2 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004553 413.0
HFD3_k127_4034611_3 Rieske 2Fe-2S - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004397 417.0
HFD3_k127_4034611_4 NADPH:quinone reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 336.0
HFD3_k127_4034611_5 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 310.0
HFD3_k127_4034611_6 carboxymuconolactone decarboxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006622 284.0
HFD3_k127_4034611_7 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005522 270.0
HFD3_k127_4034611_8 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000000000000000000000000008695 190.0
HFD3_k127_4034611_9 Trehalose synthase - - - 0.00000000000000000000000000000000000009367 150.0
HFD3_k127_4104499_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1401.0
HFD3_k127_4104499_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 6.59e-300 932.0
HFD3_k127_4104499_10 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0008935,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016043,GO:0016829,GO:0016830,GO:0016833,GO:0022607,GO:0034214,GO:0042180,GO:0042181,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:1901576,GO:1901661,GO:1901663 4.1.3.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 543.0
HFD3_k127_4104499_11 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 533.0
HFD3_k127_4104499_12 polysaccharide biosynthetic process K01992 GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0008150,GO:0009987,GO:0044764,GO:0046812,GO:0051704 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004465 535.0
HFD3_k127_4104499_13 glycosyl transferase group 1 K00786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 505.0
HFD3_k127_4104499_14 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 475.0
HFD3_k127_4104499_15 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901576 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 430.0
HFD3_k127_4104499_16 Enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008099 413.0
HFD3_k127_4104499_17 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 412.0
HFD3_k127_4104499_18 Nucleotidyl transferase K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007834 406.0
HFD3_k127_4104499_19 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 408.0
HFD3_k127_4104499_2 Glycosyltransferase like family 2 - - - 1.019e-286 915.0
HFD3_k127_4104499_20 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA K00674 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008666,GO:0016020,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0030312,GO:0031402,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0071944 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 396.0
HFD3_k127_4104499_21 ATPases associated with a variety of cellular activities K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005514 390.0
HFD3_k127_4104499_22 leucyl aminopeptidase, aminopeptidase T K18028 - 1.13.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 393.0
HFD3_k127_4104499_23 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K00446 - 1.13.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 387.0
HFD3_k127_4104499_24 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 377.0
HFD3_k127_4104499_25 TOBE domain K02017,K02018 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 375.0
HFD3_k127_4104499_26 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 359.0
HFD3_k127_4104499_27 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009931 353.0
HFD3_k127_4104499_28 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 345.0
HFD3_k127_4104499_29 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 329.0
HFD3_k127_4104499_3 Psort location CytoplasmicMembrane, score - - - 1.255e-276 879.0
HFD3_k127_4104499_30 Fumarylacetoacetate (FAA) hydrolase family K18364 - 4.2.1.132,4.2.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 321.0
HFD3_k127_4104499_32 Cell envelope-related transcriptional attenuator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 314.0
HFD3_k127_4104499_33 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009387 306.0
HFD3_k127_4104499_34 Molybdate ABC transporter K02017,K02018 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 302.0
HFD3_k127_4104499_35 D-alanyl-D-alanine carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 304.0
HFD3_k127_4104499_36 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006628 298.0
HFD3_k127_4104499_37 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 299.0
HFD3_k127_4104499_38 Fumarylacetoacetate (FAA) hydrolase family K01617 - 4.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002118 284.0
HFD3_k127_4104499_39 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006044 294.0
HFD3_k127_4104499_4 Biotin carboxylase C-terminal domain K11263 - 6.3.4.14,6.4.1.2,6.4.1.3 9.682e-272 862.0
HFD3_k127_4104499_40 dTDP-4-dehydrorhamnose 3,5-epimerase activity K00067,K01710,K01790 - 1.1.1.133,4.2.1.46,5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001801 277.0
HFD3_k127_4104499_41 serine-type endopeptidase activity K04771 GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002756 280.0
HFD3_k127_4104499_42 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000536 278.0
HFD3_k127_4104499_43 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005143 246.0
HFD3_k127_4104499_44 Histidine phosphatase superfamily (branch 1) - - - 0.0000000000000000000000000000000000000000000000000000000000000000003939 246.0
HFD3_k127_4104499_45 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000001172 225.0
HFD3_k127_4104499_46 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000000000001028 216.0
HFD3_k127_4104499_47 PFAM globin K06886 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0015669,GO:0015671,GO:0015893,GO:0016020,GO:0019825,GO:0020037,GO:0036094,GO:0042221,GO:0042493,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051179,GO:0051234,GO:0071944,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000004093 206.0
HFD3_k127_4104499_48 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000005546 184.0
HFD3_k127_4104499_49 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000005843 200.0
HFD3_k127_4104499_5 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.331e-263 818.0
HFD3_k127_4104499_50 Alpha beta hydrolase K01055 - 3.1.1.24 0.00000000000000000000000000000000000000000000008214 182.0
HFD3_k127_4104499_51 competence protein K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000006609 174.0
HFD3_k127_4104499_52 - - - - 0.0000000000000000000000000000000000000000000008688 176.0
HFD3_k127_4104499_53 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.0000000000000000000000000000000000000000002916 168.0
HFD3_k127_4104499_54 - - - - 0.000000000000000000000000000000000000001962 155.0
HFD3_k127_4104499_55 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000005851 150.0
HFD3_k127_4104499_56 amino acid - - - 0.00000000000000000000000000000000000006157 160.0
HFD3_k127_4104499_57 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000008925 139.0
HFD3_k127_4104499_58 SnoaL-like domain K06893 - - 0.00000000000000000000000000000000153 134.0
HFD3_k127_4104499_59 regulation of RNA biosynthetic process - - - 0.0000000000000000000000000000001662 133.0
HFD3_k127_4104499_6 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.084e-243 761.0
HFD3_k127_4104499_60 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.000000000000000000000000000002434 131.0
HFD3_k127_4104499_61 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.0000000000000000000000005885 107.0
HFD3_k127_4104499_63 RDD family - - - 0.000000000001434 78.0
HFD3_k127_4104499_64 Iron-containing redox enzyme K06137 - 1.3.3.11 0.00000000001157 74.0
HFD3_k127_4104499_65 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000002359 68.0
HFD3_k127_4104499_66 Iron-containing redox enzyme K06137 - 1.3.3.11 0.0000000003067 70.0
HFD3_k127_4104499_67 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.0000002343 58.0
HFD3_k127_4104499_69 aldehyde oxidase and xanthine dehydrogenase a b hammerhead - - - 0.0007624 51.0
HFD3_k127_4104499_7 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 9.485e-219 685.0
HFD3_k127_4104499_8 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840 - 5.4.2.8 7.478e-209 657.0
HFD3_k127_4104499_9 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 559.0
HFD3_k127_4131669_0 Hydroxymethylglutaryl-coenzyme A reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782 562.0
HFD3_k127_4131669_1 Domain of unknown function DUF11 - - - 0.0000000000000003536 92.0
HFD3_k127_4241835_0 C-terminal, D2-small domain, of ClpB protein K03695 - - 0.0 1328.0
HFD3_k127_4241835_1 Heat shock 70 kDa protein K04043 - - 0.0 1027.0
HFD3_k127_4241835_10 MMPL family K06994 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 559.0
HFD3_k127_4241835_11 protein secretion K20276,K21449 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 531.0
HFD3_k127_4241835_12 associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 457.0
HFD3_k127_4241835_13 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009956 400.0
HFD3_k127_4241835_14 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 394.0
HFD3_k127_4241835_15 DNA segregation ATPase FtsK SpoIIIE and related K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 418.0
HFD3_k127_4241835_16 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 359.0
HFD3_k127_4241835_17 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 344.0
HFD3_k127_4241835_18 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005727 334.0
HFD3_k127_4241835_19 Thioesterase-like superfamily K10805 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 313.0
HFD3_k127_4241835_2 4Fe-4S dicluster domain - - - 9.854e-316 974.0
HFD3_k127_4241835_20 sugar isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 306.0
HFD3_k127_4241835_21 phosphoglycerate mutase activity K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 303.0
HFD3_k127_4241835_22 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 309.0
HFD3_k127_4241835_23 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 317.0
HFD3_k127_4241835_24 Two component transcriptional regulator, winged helix family K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 291.0
HFD3_k127_4241835_25 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000852 299.0
HFD3_k127_4241835_26 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000457 279.0
HFD3_k127_4241835_27 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001456 267.0
HFD3_k127_4241835_28 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001517 277.0
HFD3_k127_4241835_29 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000006754 238.0
HFD3_k127_4241835_3 metallocarboxypeptidase activity - - - 1.543e-244 767.0
HFD3_k127_4241835_30 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000269 224.0
HFD3_k127_4241835_31 - - - - 0.0000000000000000000000000000000000000000000000000002422 196.0
HFD3_k127_4241835_32 Aminoglycoside phosphotransferase K16146 - 2.7.1.175 0.000000000000000000000000000000000000000000000000004335 196.0
HFD3_k127_4241835_33 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000000205 174.0
HFD3_k127_4241835_34 Flavodoxin reductases ferredoxin-NADPH reductases family 1 - - - 0.0000000000000000000000000000000000000000006673 169.0
HFD3_k127_4241835_35 helix_turn_helix, mercury resistance K13640 - - 0.00000000000000000000000000000000000466 154.0
HFD3_k127_4241835_36 - - - - 0.00000000000000000000000000000000006321 137.0
HFD3_k127_4241835_37 B domain of TMEM189, localisation domain K20656 - - 0.000000000000000000000000000000000108 141.0
HFD3_k127_4241835_38 - - - - 0.000000000000000000000000000008705 132.0
HFD3_k127_4241835_4 Peptidase family M41 - - - 2.605e-214 682.0
HFD3_k127_4241835_40 cyclic nucleotide binding K10914 - - 0.000000000000000000000000006335 117.0
HFD3_k127_4241835_41 RF-1 domain K15034 - - 0.000000000000003607 81.0
HFD3_k127_4241835_42 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.000000000000008473 89.0
HFD3_k127_4241835_43 SWIM zinc finger - - - 0.0000000001724 73.0
HFD3_k127_4241835_5 Adenylosuccinate lyase C-terminus K01756 - 4.3.2.2 2.018e-197 633.0
HFD3_k127_4241835_6 Glycosyltransferase, MGT family - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0009058,GO:0009247,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0020012,GO:0030682,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044464,GO:0046467,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071704,GO:0071944,GO:0075136,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 608.0
HFD3_k127_4241835_7 Non-specific serine threonine protein kinase K08282 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008427 620.0
HFD3_k127_4241835_8 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006576 579.0
HFD3_k127_4241835_9 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 571.0
HFD3_k127_4304511_0 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 309.0
HFD3_k127_4304511_1 PFAM Endonuclease exonuclease phosphatase K07004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009444 282.0
HFD3_k127_4304511_2 Uncharacterized protein conserved in bacteria (DUF2087) - - - 0.0000000000000000000000000000000000003677 154.0
HFD3_k127_4304511_3 DnaJ molecular chaperone homology domain K03686 - - 0.000000000000000000000002891 109.0
HFD3_k127_4321229_0 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 627.0
HFD3_k127_4321229_1 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 362.0
HFD3_k127_4321229_2 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002725 261.0
HFD3_k127_4321229_3 Histidine kinase K07642 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000003506 202.0
HFD3_k127_4321229_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000002486 165.0
HFD3_k127_4321229_5 - - - - 0.000000000000000000000000007347 115.0
HFD3_k127_4321229_6 Protein of unknown function (DUF4243) - - - 0.000000000000000007012 92.0
HFD3_k127_4321229_7 Protein of unknown function with PCYCGC motif - - - 0.0000000002719 68.0
HFD3_k127_4321229_8 - - - - 0.00002981 54.0
HFD3_k127_4325476_0 DNA polymerase alpha chain like domain K02337 - 2.7.7.7 0.0 1772.0
HFD3_k127_4325476_1 Protein of unknown function, DUF255 K06888 - - 9.375e-261 818.0
HFD3_k127_4325476_10 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 359.0
HFD3_k127_4325476_11 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 325.0
HFD3_k127_4325476_12 Serine threonine protein kinase involved in cell cycle control K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 316.0
HFD3_k127_4325476_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 296.0
HFD3_k127_4325476_14 Acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000001789 263.0
HFD3_k127_4325476_15 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000001935 241.0
HFD3_k127_4325476_16 HIT domain K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000000000000000188 224.0
HFD3_k127_4325476_17 - - - - 0.00000000000000000000000000000000000000000000000000000000009473 209.0
HFD3_k127_4325476_18 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters - - - 0.000000000000000000000000000000000000000000000000000000002948 209.0
HFD3_k127_4325476_19 Protein of unknown function (DUF1524) - - - 0.00000000000000000000000000000000000000000000000000094 193.0
HFD3_k127_4325476_2 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 9.637e-229 725.0
HFD3_k127_4325476_20 Protein of unknown function (DUF2587) - - - 0.000000000000000000000000000000000000000000000000006023 187.0
HFD3_k127_4325476_21 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000000000006744 181.0
HFD3_k127_4325476_22 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000005596 176.0
HFD3_k127_4325476_23 Nitroreductase family - - - 0.0000000000000000000000000000000000000000001405 171.0
HFD3_k127_4325476_3 tRNA synthetases class I (C) catalytic domain K15526 - 6.3.1.13 2.176e-196 616.0
HFD3_k127_4325476_4 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 417.0
HFD3_k127_4325476_5 Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007349 441.0
HFD3_k127_4325476_6 transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004946 426.0
HFD3_k127_4325476_7 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 407.0
HFD3_k127_4325476_8 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009771 364.0
HFD3_k127_4325476_9 Bacterial lipid A biosynthesis acyltransferase K22311 - 2.3.1.265 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 365.0
HFD3_k127_4394045_0 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004726 258.0
HFD3_k127_4394045_1 Protein of unknown function (DUF664) - - - 0.000000000000000000000000000000000000000000000000000000000000002269 229.0
HFD3_k127_4394045_2 DNA synthesis involved in DNA repair - - - 0.00000000000000000000000000000000000000000000000000000000000003082 224.0
HFD3_k127_4394045_3 Methyltransferase domain - - - 0.000000000000000000000000000000003201 136.0
HFD3_k127_4394045_4 belongs to the sigma-70 factor family, ECF subfamily - - - 0.00000000000000000000000008397 112.0
HFD3_k127_4394045_5 guanyl-nucleotide exchange factor activity K20276 - - 0.00000000000000003541 84.0
HFD3_k127_4394045_6 Putative cyclase - - - 0.00000000003861 64.0
HFD3_k127_4394045_7 Bacterial regulatory proteins, tetR family - - - 0.00000000435 64.0
HFD3_k127_4500370_0 Pilus assembly protein PilX K02673 - - 0.000509 53.0
HFD3_k127_4500370_1 - - - - 0.0005997 43.0
HFD3_k127_4672585_0 FAD dependent oxidoreductase central domain K19191 - 1.5.3.19 0.0 1202.0
HFD3_k127_4672585_1 Peroxidase K03782 - 1.11.1.21 0.0 1192.0
HFD3_k127_4672585_10 TIGRFAM NRAMP (natural resistance-associated macrophage protein) metal ion transporters - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008046 435.0
HFD3_k127_4672585_11 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005011 442.0
HFD3_k127_4672585_12 PQQ enzyme repeat K05889,K12132 - 1.1.2.6,2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005653 422.0
HFD3_k127_4672585_13 Sodium/calcium exchanger protein K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 377.0
HFD3_k127_4672585_14 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005493 389.0
HFD3_k127_4672585_15 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 368.0
HFD3_k127_4672585_16 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005192 344.0
HFD3_k127_4672585_17 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 310.0
HFD3_k127_4672585_18 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004113 304.0
HFD3_k127_4672585_19 Bacterial protein of unknown function (DUF899) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 299.0
HFD3_k127_4672585_2 FAD dependent oxidoreductase central domain - - - 3.909e-286 901.0
HFD3_k127_4672585_20 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 298.0
HFD3_k127_4672585_21 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 286.0
HFD3_k127_4672585_22 PFAM cyclase family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006949 277.0
HFD3_k127_4672585_23 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000749 290.0
HFD3_k127_4672585_24 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003397 271.0
HFD3_k127_4672585_25 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000022 268.0
HFD3_k127_4672585_26 cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000001678 241.0
HFD3_k127_4672585_27 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002997 247.0
HFD3_k127_4672585_28 PFAM CoA-binding domain protein K06929 - - 0.00000000000000000000000000000000000000000000000000000000000000001794 226.0
HFD3_k127_4672585_29 PFAM Uracil-DNA glycosylase superfamily K03649 - 3.2.2.28 0.0000000000000000000000000000000000000000000000000000000000000000211 233.0
HFD3_k127_4672585_3 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007267 587.0
HFD3_k127_4672585_30 - - - - 0.00000000000000000000000000000000000000000000000000000000000000008424 235.0
HFD3_k127_4672585_31 Molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000004842 218.0
HFD3_k127_4672585_32 PFAM Activator of Hsp90 ATPase 1 family protein - - - 0.0000000000000000000000000000000000000000000000000000000005995 211.0
HFD3_k127_4672585_33 Acetyltransferase (GNAT) domain K03825 - - 0.000000000000000000000000000000000000000000000000000000002325 206.0
HFD3_k127_4672585_34 Ferric uptake regulator family K22297 - - 0.0000000000000000000000000000000000000000000000000000001147 202.0
HFD3_k127_4672585_35 Diguanylate cyclase with PAS PAC and GAF sensors - - - 0.000000000000000000000000000000000000000000000000000001167 208.0
HFD3_k127_4672585_36 Haem-degrading - - - 0.000000000000000000000000000000000000000000000000000002918 201.0
HFD3_k127_4672585_37 May play a role in the intracellular transport of hydrophobic ligands - - - 0.000000000000000000000000000000000000000000000000000009691 201.0
HFD3_k127_4672585_38 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000004015 188.0
HFD3_k127_4672585_39 - - - - 0.00000000000000000000000000000000000000000000000000294 192.0
HFD3_k127_4672585_4 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 536.0
HFD3_k127_4672585_40 N-acetylglucosaminylinositol deacetylase activity - - - 0.00000000000000000000000000000000000000000000000003224 194.0
HFD3_k127_4672585_41 - - - - 0.000000000000000000000000000000000000000000000002867 184.0
HFD3_k127_4672585_42 MaoC like domain - - - 0.000000000000000000000000000000000000000000000004646 187.0
HFD3_k127_4672585_43 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000002322 180.0
HFD3_k127_4672585_44 of the double-stranded beta helix - - - 0.000000000000000000000000000000000000000000000215 176.0
HFD3_k127_4672585_45 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.0000000000000000000000000000000000000000000002212 175.0
HFD3_k127_4672585_46 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000004843 173.0
HFD3_k127_4672585_47 SMART Rhodanese domain protein - - - 0.0000000000000000000000000000000000000000000007655 181.0
HFD3_k127_4672585_48 Transcription regulator MerR, DNA binding - - - 0.00000000000000000000000000000000000000000001915 171.0
HFD3_k127_4672585_49 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.00000000000000000000000000000000000000000003405 171.0
HFD3_k127_4672585_5 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 516.0
HFD3_k127_4672585_51 Transcriptional regulator ArsR family - - - 0.0000000000000000000000000000000001682 136.0
HFD3_k127_4672585_52 transcriptional regulator - - - 0.00000000000000000000000000000001082 136.0
HFD3_k127_4672585_53 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000001719 141.0
HFD3_k127_4672585_54 PFAM transcriptional regulator PadR family protein - - - 0.00000000000000000000000000000001854 133.0
HFD3_k127_4672585_55 Domain of unknown function (DUF4389) - - - 0.0000000000000000000000000000003843 134.0
HFD3_k127_4672585_56 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000004079 124.0
HFD3_k127_4672585_58 - - - - 0.0000000000000000001179 94.0
HFD3_k127_4672585_59 Putative sensor - - - 0.00000000000000005001 91.0
HFD3_k127_4672585_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 483.0
HFD3_k127_4672585_60 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000005396 90.0
HFD3_k127_4672585_62 - - - - 0.000000000000001351 83.0
HFD3_k127_4672585_63 SnoaL-like polyketide cyclase - - - 0.000000000000003721 83.0
HFD3_k127_4672585_64 Baseplate assembly protein - - - 0.00000000000006336 78.0
HFD3_k127_4672585_65 DUF167 K09131 - - 0.0000000000001659 74.0
HFD3_k127_4672585_66 Baseplate assembly protein - - - 0.000000000003619 73.0
HFD3_k127_4672585_67 Scaffold protein Nfu/NifU N terminal - - - 0.000007758 52.0
HFD3_k127_4672585_68 - - - - 0.00004623 53.0
HFD3_k127_4672585_7 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005822 492.0
HFD3_k127_4672585_8 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008803 484.0
HFD3_k127_4672585_9 Ecdysteroid kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006966 451.0
HFD3_k127_4679978_0 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007719 383.0
HFD3_k127_4679978_1 Protein of unknown function (DUF1326) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009378 351.0
HFD3_k127_4679978_2 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002411 263.0
HFD3_k127_4679978_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000003184 156.0
HFD3_k127_4679978_4 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.0000000000000000000000000000000002257 135.0
HFD3_k127_4679978_5 Peptidase S9, prolyl oligopeptidase active site domain protein - - - 0.000000004462 68.0
HFD3_k127_4679978_6 Belongs to the peptidase S16 family K07177 - - 0.0000009054 60.0
HFD3_k127_4679978_7 PFAM IstB domain protein ATP-binding protein - - - 0.0003497 47.0
HFD3_k127_4690957_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1296.0
HFD3_k127_4690957_1 Thiamine pyrophosphate enzyme, central domain K03336 - 3.7.1.22 1.435e-234 740.0
HFD3_k127_4690957_10 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006306 493.0
HFD3_k127_4690957_11 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 494.0
HFD3_k127_4690957_12 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006841 473.0
HFD3_k127_4690957_13 ABC transporter K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007848 449.0
HFD3_k127_4690957_14 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008065 455.0
HFD3_k127_4690957_15 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008686 452.0
HFD3_k127_4690957_16 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008416 460.0
HFD3_k127_4690957_17 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 454.0
HFD3_k127_4690957_18 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 444.0
HFD3_k127_4690957_19 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005901 410.0
HFD3_k127_4690957_2 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 4.31e-232 726.0
HFD3_k127_4690957_20 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 417.0
HFD3_k127_4690957_21 ROK family K00845,K00886 - 2.7.1.2,2.7.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 399.0
HFD3_k127_4690957_22 KduI/IolB family K03337 - 5.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 396.0
HFD3_k127_4690957_23 Cell cycle protein K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 399.0
HFD3_k127_4690957_24 4Fe-4S double cluster binding domain K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 387.0
HFD3_k127_4690957_25 pfkB family carbohydrate kinase K03338 - 2.7.1.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 370.0
HFD3_k127_4690957_26 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 371.0
HFD3_k127_4690957_27 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 357.0
HFD3_k127_4690957_28 transport, permease protein K09694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000659 344.0
HFD3_k127_4690957_29 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 357.0
HFD3_k127_4690957_3 Aminotransferase class I and II K14261 - - 3.53e-220 687.0
HFD3_k127_4690957_30 helix_turn _helix lactose operon repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 332.0
HFD3_k127_4690957_31 AMP-binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003756 320.0
HFD3_k127_4690957_32 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000472 325.0
HFD3_k127_4690957_33 deoxyribose-phosphate aldolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008897 304.0
HFD3_k127_4690957_34 ABC transporter substrate-binding protein K02058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 297.0
HFD3_k127_4690957_35 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002483 284.0
HFD3_k127_4690957_36 Inositol monophosphatase K01092 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043167,GO:0043169,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000002625 276.0
HFD3_k127_4690957_37 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001651 268.0
HFD3_k127_4690957_38 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001669 259.0
HFD3_k127_4690957_39 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000002128 255.0
HFD3_k127_4690957_4 Acyl-CoA dehydrogenase, N-terminal domain - - - 2.286e-211 661.0
HFD3_k127_4690957_40 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003043 245.0
HFD3_k127_4690957_41 transport, permease protein K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000471 239.0
HFD3_k127_4690957_42 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000101 231.0
HFD3_k127_4690957_43 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000001535 220.0
HFD3_k127_4690957_44 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000003318 215.0
HFD3_k127_4690957_45 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000001411 217.0
HFD3_k127_4690957_46 Alanine racemase, N-terminal domain K06997 - - 0.0000000000000000000000000000000000000000000000000000000003656 209.0
HFD3_k127_4690957_47 regulation of cell shape - - - 0.0000000000000000000000000000000000000000000000000000007888 203.0
HFD3_k127_4690957_48 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589,K06438 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 6.3.2.4 0.00000000000000000000000000000000000000000000000000001548 204.0
HFD3_k127_4690957_49 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000998 210.0
HFD3_k127_4690957_5 Belongs to the MurCDEF family K01924 - 6.3.2.8 1.435e-200 637.0
HFD3_k127_4690957_50 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA K09772 - - 0.0000000000000000000000000000000000000000000000000007742 198.0
HFD3_k127_4690957_51 molybdenum ion binding K07140 - - 0.000000000000000000000000000000000000000000002874 175.0
HFD3_k127_4690957_52 Lipoate-protein ligase - - - 0.0000000000000000000000000000000000000008972 157.0
HFD3_k127_4690957_53 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000001876 161.0
HFD3_k127_4690957_54 MraZ protein, putative antitoxin-like K03925 - - 0.000000000000000000000000000000000005672 142.0
HFD3_k127_4690957_55 GDP-mannose mannosyl hydrolase activity K08310 - 3.6.1.67 0.00000000000000000000000000000000001239 141.0
HFD3_k127_4690957_56 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000002686 135.0
HFD3_k127_4690957_58 - - - - 0.0000000000000000000001385 103.0
HFD3_k127_4690957_6 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009829 577.0
HFD3_k127_4690957_63 PFAM Sporulation and spore germination - - - 0.00001035 55.0
HFD3_k127_4690957_64 Sortase family - - - 0.00001266 56.0
HFD3_k127_4690957_65 - - - - 0.000123 48.0
HFD3_k127_4690957_7 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 537.0
HFD3_k127_4690957_8 Glycosyl transferases group 1 K13668 - 2.4.1.346 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 530.0
HFD3_k127_4690957_9 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 514.0
HFD3_k127_4701199_0 Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 455.0
HFD3_k127_4701199_1 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001884 283.0
HFD3_k127_4701199_2 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002462 286.0
HFD3_k127_4701199_3 AIR carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000003368 222.0
HFD3_k127_4701199_4 Thioesterase-like superfamily - - - 0.000000000000000000000000000000000000000000000004203 185.0
HFD3_k127_4701199_5 Cyclic nucleotide-binding domain - - - 0.000000000008023 74.0
HFD3_k127_4705215_0 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000000000000000000000008225 220.0
HFD3_k127_4705215_1 peroxiredoxin activity K01607 - 4.1.1.44 0.000000000000000000000003309 115.0
HFD3_k127_4705215_2 PFAM flavin reductase domain protein FMN-binding - - - 0.00000000000000000000001055 105.0
HFD3_k127_4714981_0 Succinyl-CoA ligase like flavodoxin domain - - - 6.977e-228 745.0
HFD3_k127_4714981_1 Aldo Keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006291 529.0
HFD3_k127_4714981_10 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000206 227.0
HFD3_k127_4714981_11 Peptidase C26 - - - 0.0000000000000000000000000000000000000000000000000000002229 212.0
HFD3_k127_4714981_12 Histidine kinase - - - 0.000000000000000000000000000000000000000000009049 175.0
HFD3_k127_4714981_13 Universal stress protein family - - - 0.00000000000000000000000000000000000000006421 166.0
HFD3_k127_4714981_14 FMN binding K03809 - 1.6.5.2 0.000000000000000000000000000000003575 135.0
HFD3_k127_4714981_15 transcriptional regulator - - - 0.000000000000000000000000000000007929 137.0
HFD3_k127_4714981_16 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000002721 133.0
HFD3_k127_4714981_17 Belongs to the small heat shock protein (HSP20) family K13993 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016310,GO:0019538,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0036294,GO:0040007,GO:0040008,GO:0042221,GO:0042594,GO:0043170,GO:0043207,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045926,GO:0046777,GO:0048519,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071496,GO:0071704,GO:0071944,GO:0075136,GO:1901564 - 0.0000000000000000000000000005258 118.0
HFD3_k127_4714981_18 translation release factor activity - - - 0.000000000000000000000000001839 127.0
HFD3_k127_4714981_19 PAS domain - - - 0.000000000000000000002768 101.0
HFD3_k127_4714981_2 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00758 - 2.4.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009847 514.0
HFD3_k127_4714981_20 PFAM Sporulation and spore germination - - - 0.00000000000000000194 97.0
HFD3_k127_4714981_21 CBS domains - - - 0.0000000000000005123 80.0
HFD3_k127_4714981_22 - - - - 0.00000003359 62.0
HFD3_k127_4714981_23 Belongs to the universal stress protein A family - - - 0.00000599 56.0
HFD3_k127_4714981_3 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 445.0
HFD3_k127_4714981_4 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 414.0
HFD3_k127_4714981_5 with different specificities (related to short-chain alcohol - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 367.0
HFD3_k127_4714981_6 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000598 298.0
HFD3_k127_4714981_7 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001267 273.0
HFD3_k127_4714981_8 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002938 272.0
HFD3_k127_4714981_9 Belongs to the peptidase M50B family - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004705 274.0
HFD3_k127_4751358_0 MMPL family K06994,K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691 433.0
HFD3_k127_4751358_1 Amino acid amide ABC transporter substrate-binding protein, HAAT family K01999 - - 0.000000000000000000000002207 117.0
HFD3_k127_4751358_2 RIO1 family - - - 0.0007204 44.0
HFD3_k127_4760062_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1101.0
HFD3_k127_4760062_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 2.03e-312 969.0
HFD3_k127_4760062_10 cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 421.0
HFD3_k127_4760062_11 Glycosyl transferases group 1 K08256 - 2.4.1.345 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 413.0
HFD3_k127_4760062_12 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 379.0
HFD3_k127_4760062_13 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 344.0
HFD3_k127_4760062_14 Amidinotransferase K01482 - 3.5.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 344.0
HFD3_k127_4760062_15 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 344.0
HFD3_k127_4760062_16 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 297.0
HFD3_k127_4760062_17 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001129 267.0
HFD3_k127_4760062_18 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000003945 235.0
HFD3_k127_4760062_19 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000008521 246.0
HFD3_k127_4760062_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 1.965e-257 804.0
HFD3_k127_4760062_20 Protein of unknown function (DUF3048) C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000005214 239.0
HFD3_k127_4760062_21 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000007517 229.0
HFD3_k127_4760062_22 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000000000000000007495 217.0
HFD3_k127_4760062_23 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000003037 226.0
HFD3_k127_4760062_24 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.0000000000000000000000000000000000000000000000000007606 196.0
HFD3_k127_4760062_25 Protein of unknown function (DUF3048) C-terminal domain - - - 0.00000000000000000000000000000000000000000000000005171 192.0
HFD3_k127_4760062_26 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009378,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360 3.6.4.12 0.00000000000000000000000000000000000000000000002181 177.0
HFD3_k127_4760062_27 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07667 - - 0.00000000000000000000000000000000000000006054 155.0
HFD3_k127_4760062_28 Preprotein translocase subunit YajC K03210 - - 0.000000000000000000000008015 106.0
HFD3_k127_4760062_29 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.00000000000000000007131 102.0
HFD3_k127_4760062_3 Domain of unknown function (DUF4118) K07646 - 2.7.13.3 1.738e-232 745.0
HFD3_k127_4760062_30 - - - - 0.00000000002263 70.0
HFD3_k127_4760062_31 F subunit of K+-transporting ATPase (Potass_KdpF) - - - 0.0006089 44.0
HFD3_k127_4760062_4 Amino acid permease - - - 1.601e-194 632.0
HFD3_k127_4760062_5 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 578.0
HFD3_k127_4760062_6 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 520.0
HFD3_k127_4760062_7 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 506.0
HFD3_k127_4760062_8 Peptidase family M48 K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 468.0
HFD3_k127_4760062_9 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 430.0
HFD3_k127_4773440_0 RecF/RecN/SMC N terminal domain K03529 - - 0.0 1320.0
HFD3_k127_4773440_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 1.035e-220 698.0
HFD3_k127_4773440_10 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 347.0
HFD3_k127_4773440_11 ABC-type spermidine putrescine transport system, permease component I K02054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 321.0
HFD3_k127_4773440_12 ABC-type spermidine putrescine transport system, permease component II K02053 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009465 320.0
HFD3_k127_4773440_13 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005096 312.0
HFD3_k127_4773440_14 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000008354 246.0
HFD3_k127_4773440_15 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000003804 228.0
HFD3_k127_4773440_16 NAD(P)H dehydrogenase (quinone) activity K00355 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000001797 214.0
HFD3_k127_4773440_17 Protein conserved in bacteria K03654 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000233 216.0
HFD3_k127_4773440_18 NAD(P)H dehydrogenase (quinone) activity K00355 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000001229 209.0
HFD3_k127_4773440_19 LysE type translocator K11250 - - 0.0000000000000000000000000000000000000000000000000002118 192.0
HFD3_k127_4773440_2 Epoxide hydrolase N terminus K21159 - - 1.113e-196 619.0
HFD3_k127_4773440_20 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000000000000004222 190.0
HFD3_k127_4773440_21 - - - - 0.00000000000000000000000000000000000000000000001337 181.0
HFD3_k127_4773440_22 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000001201 180.0
HFD3_k127_4773440_23 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000006188 169.0
HFD3_k127_4773440_24 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000001071 142.0
HFD3_k127_4773440_26 Ribosomal protein S16 K02959 - - 0.0000000000000000000000000000000008614 137.0
HFD3_k127_4773440_27 nuclease activity K07460 - - 0.000000000000000000000000000000001896 136.0
HFD3_k127_4773440_28 Protein of unknown function (DUF2469) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000007321 128.0
HFD3_k127_4773440_29 Belongs to the UPF0109 family K06960 GO:0008150,GO:0040007 - 0.000000000000000000000003278 104.0
HFD3_k127_4773440_3 Transketolase, C-terminal domain K00167 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 582.0
HFD3_k127_4773440_30 - - - - 0.00000000000000000000003296 116.0
HFD3_k127_4773440_31 Protein of unknown function (DUF952) - - - 0.00000000000000000003625 103.0
HFD3_k127_4773440_32 - - - - 0.000000000000003352 84.0
HFD3_k127_4773440_4 Dehydrogenase E1 component K00166 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 559.0
HFD3_k127_4773440_5 Bacterial extracellular solute-binding protein K02055 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006193 496.0
HFD3_k127_4773440_6 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K09699 - 2.3.1.168 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 441.0
HFD3_k127_4773440_7 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 431.0
HFD3_k127_4773440_8 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 425.0
HFD3_k127_4773440_9 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 369.0
HFD3_k127_4789476_0 Belongs to the thiolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 484.0
HFD3_k127_4789476_1 PFAM AMP-dependent synthetase and ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 471.0
HFD3_k127_4789476_10 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000002365 192.0
HFD3_k127_4789476_11 pyridoxamine 5-phosphate - - - 0.0000000000000000000000000000000000000000000000000867 187.0
HFD3_k127_4789476_12 lactoylglutathione lyase activity - - - 0.000000000000000115 82.0
HFD3_k127_4789476_13 Alcohol dehydrogenase GroES-like domain - - - 0.000000004259 62.0
HFD3_k127_4789476_2 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 416.0
HFD3_k127_4789476_3 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 398.0
HFD3_k127_4789476_4 F420-dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 354.0
HFD3_k127_4789476_5 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009808 340.0
HFD3_k127_4789476_6 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 293.0
HFD3_k127_4789476_7 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007111 265.0
HFD3_k127_4789476_8 Enoyl-CoA hydratase/isomerase K01692,K07546 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000001709 260.0
HFD3_k127_4789476_9 Ankyrin repeats (3 copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007268 252.0
HFD3_k127_4801968_0 assembly protein SufB K09014 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - 9.241e-283 892.0
HFD3_k127_4801968_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 1.071e-197 623.0
HFD3_k127_4801968_10 Aminoacyl-tRNA editing domain - - - 0.0000000000000000000000000000000000000000000000000000000000006854 214.0
HFD3_k127_4801968_11 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000000000000000000000006985 215.0
HFD3_k127_4801968_12 FeS assembly protein SufD K07033,K09015 GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0040007,GO:0043207,GO:0044085,GO:0044237,GO:0044403,GO:0044419,GO:0050896,GO:0051186,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071840,GO:0075136 - 0.000000000000000000000000000000000000000000000000000001595 205.0
HFD3_k127_4801968_14 PIN domain K07064 - - 0.000000000000000000000000000000000000000007428 163.0
HFD3_k127_4801968_15 - - - - 0.0000000000000000000000000000000000000008231 152.0
HFD3_k127_4801968_16 Family of unknown function (DUF5317) - - - 0.000000000000000000000000000000000000001892 153.0
HFD3_k127_4801968_17 electron transfer activity K05337 GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114 - 0.0000000000000000000000000000004666 128.0
HFD3_k127_4801968_18 Rieske-like [2Fe-2S] domain K05710 - - 0.0000000000000000000000000006985 116.0
HFD3_k127_4801968_19 positive regulation of growth - - - 0.0000000000000005129 80.0
HFD3_k127_4801968_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 624.0
HFD3_k127_4801968_3 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 - 3.4.21.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004791 510.0
HFD3_k127_4801968_4 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 387.0
HFD3_k127_4801968_5 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003695 338.0
HFD3_k127_4801968_6 unsaturated fatty acid biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 331.0
HFD3_k127_4801968_7 FeS assembly ATPase SufC K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 306.0
HFD3_k127_4801968_8 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000324 281.0
HFD3_k127_4801968_9 ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005238 252.0
HFD3_k127_4825891_0 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) - - - 7.499e-231 724.0
HFD3_k127_48378_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000001188 183.0
HFD3_k127_48378_1 4Fe-4S dicluster domain - - - 0.00000000000001207 74.0
HFD3_k127_4840669_0 Predicted membrane protein (DUF2207) - - - 0.00000000000000000000000000000000000000000000001516 195.0
HFD3_k127_4840669_1 Prokaryotic dksA/traR C4-type zinc finger - - - 0.000000000000000000000283 113.0
HFD3_k127_4840669_2 ROK family - - - 0.00000000000003656 73.0
HFD3_k127_4854688_0 glycoside hydrolase 15-related K01178 - 3.2.1.3 0.0 1364.0
HFD3_k127_4854688_1 Alpha-amylase domain K01187 - 3.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 603.0
HFD3_k127_4854688_10 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division - GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000002884 109.0
HFD3_k127_4854688_2 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006886 499.0
HFD3_k127_4854688_3 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005255 463.0
HFD3_k127_4854688_4 Signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 405.0
HFD3_k127_4854688_5 2OG-Fe(II) oxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000753 354.0
HFD3_k127_4854688_6 Response regulator receiver K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002744 274.0
HFD3_k127_4854688_7 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000005404 245.0
HFD3_k127_4854688_8 helix_turn _helix lactose operon repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000001373 248.0
HFD3_k127_4854688_9 - - - - 0.0000000000000000000000000000000000000001173 155.0
HFD3_k127_4879475_0 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000415 285.0
HFD3_k127_4946783_0 PFAM transcriptional regulator domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004658 407.0
HFD3_k127_4946783_1 Zinc finger domain - - - 0.0000000000000000000000000000000000000000000000000000000000000256 233.0
HFD3_k127_4946783_2 Domain of unknown function (DUF4280) - - - 0.0000000000000000000000000000000000000000000008083 169.0
HFD3_k127_4951510_0 belongs to the sigma-70 factor family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 551.0
HFD3_k127_4951510_1 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 551.0
HFD3_k127_4951510_2 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003629 274.0
HFD3_k127_4951510_3 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000000000000001072 161.0
HFD3_k127_4951510_4 PFAM monooxygenase FAD-binding - - - 0.00000000000000000000000000000000000005352 149.0
HFD3_k127_4951510_5 Glutathione-dependent formaldehyde-activating - - - 0.0000000000000000000000000000000005403 136.0
HFD3_k127_4951510_6 - - - - 0.0000000000000000000000000000004514 134.0
HFD3_k127_4951510_7 Thioesterase-like superfamily - - - 0.000000000000000000000000000002199 134.0
HFD3_k127_5014736_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1121.0
HFD3_k127_5014736_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000492 212.0
HFD3_k127_5014736_2 AAA ATPase domain - - - 0.000000000000000005196 96.0
HFD3_k127_5041612_0 Polysaccharide biosynthesis protein K17947 - 5.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000004725 257.0
HFD3_k127_5041612_1 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000003489 76.0
HFD3_k127_5041612_2 Methionine biosynthesis protein MetW - - - 0.000000001166 67.0
HFD3_k127_5115366_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K00187 - 1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 475.0
HFD3_k127_5115366_1 Lysylphosphatidylglycerol synthase TM region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 371.0
HFD3_k127_5115366_10 Protein of unknown function (DUF3995) - - - 0.00000000000000009155 89.0
HFD3_k127_5115366_11 Cupin domain - - - 0.00000002482 61.0
HFD3_k127_5115366_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007257 290.0
HFD3_k127_5115366_3 Carbon-nitrogen hydrolase K01501 - 3.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000001152 242.0
HFD3_k127_5115366_4 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000001076 201.0
HFD3_k127_5115366_5 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000000000000000000000000007601 145.0
HFD3_k127_5115366_6 Pfam:DUF385 - - - 0.00000000000000000000000000000000001786 141.0
HFD3_k127_5115366_7 NAD(P)H-dependent FMN reductase - - - 0.00000000000000000000000003147 113.0
HFD3_k127_5115366_8 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000001083 110.0
HFD3_k127_5115366_9 DNA-binding transcription factor activity - - - 0.00000000000000000003441 96.0
HFD3_k127_5150419_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K17883 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0010126,GO:0016137,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050627,GO:0050660,GO:0050661,GO:0050662,GO:0051186,GO:0055114,GO:0070402,GO:0071704,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901657 1.8.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 484.0
HFD3_k127_5150419_1 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 319.0
HFD3_k127_5150419_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001737 274.0
HFD3_k127_5150419_3 Transcriptional regulatory protein, C terminal K07669,K07672 - - 0.000000000000000000000000000000000000000000000000000000000000001365 222.0
HFD3_k127_5150419_4 - - - - 0.00000000000000000000131 105.0
HFD3_k127_5229111_0 Type II secretion system (T2SS), protein E, N-terminal domain K02652 - - 1.367e-255 800.0
HFD3_k127_5229111_1 Zinc-binding dehydrogenase K17829 - 1.3.1.86 1.312e-214 673.0
HFD3_k127_5229111_10 Protein of unknown function (DUF429) K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 295.0
HFD3_k127_5229111_11 Type IV leader peptidase family K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000005778 265.0
HFD3_k127_5229111_12 Glyoxalase-like domain K05606 - 5.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000002522 233.0
HFD3_k127_5229111_13 Phage-related minor tail protein K15771,K18642,K20444 - - 0.000000000000000000000000000000000000000000000000000001351 209.0
HFD3_k127_5229111_14 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000000000000000000000000000005481 192.0
HFD3_k127_5229111_15 Glycosyl hydrolases family 18 - - - 0.0000000000000000000000000000000000000000000000003861 191.0
HFD3_k127_5229111_17 Prokaryotic N-terminal methylation motif - - - 0.00000000000000000002852 96.0
HFD3_k127_5229111_2 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 599.0
HFD3_k127_5229111_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 603.0
HFD3_k127_5229111_4 Type II secretion system (T2SS), protein F K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 556.0
HFD3_k127_5229111_5 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003941 550.0
HFD3_k127_5229111_6 dna ligase - GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008186 460.0
HFD3_k127_5229111_7 response to copper ion K07156,K07245,K14166 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000633 412.0
HFD3_k127_5229111_8 5'-3' exonuclease, C-terminal SAM fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007178 394.0
HFD3_k127_5229111_9 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 332.0
HFD3_k127_5279156_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 545.0
HFD3_k127_5279156_1 decarboxylase K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 398.0
HFD3_k127_5279156_2 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003953 269.0
HFD3_k127_5279156_3 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K00219,K01069 - 1.3.1.34,3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000597 221.0
HFD3_k127_5279156_4 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000003381 207.0
HFD3_k127_5279156_5 Iron-sulphur cluster biosynthesis K13628 - - 0.0000000000000000000000000000000000000000002692 162.0
HFD3_k127_5279156_6 oxidation-reduction process K09022 - 3.5.99.10 0.000000000000000000000000000000006258 140.0
HFD3_k127_5279525_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 1.747e-260 811.0
HFD3_k127_5279525_1 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 2.218e-212 671.0
HFD3_k127_5279525_10 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 332.0
HFD3_k127_5279525_11 Short-chain dehydrogenase reductase sdr K14633 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006672 322.0
HFD3_k127_5279525_12 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 320.0
HFD3_k127_5279525_13 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00854,K00862,K00880 - 2.7.1.17,2.7.1.215,2.7.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 321.0
HFD3_k127_5279525_14 Rubrerythrin K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000004946 258.0
HFD3_k127_5279525_15 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000004645 244.0
HFD3_k127_5279525_16 Glucose-regulated metallo-peptidase M90 K09933 - - 0.00000000000000000000000000000000000000000000000000000000000001416 224.0
HFD3_k127_5279525_17 Domain of unknown function (DUF1932) - - - 0.00000000000000000000000000000000000000000000000000000000001278 221.0
HFD3_k127_5279525_18 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000001534 210.0
HFD3_k127_5279525_19 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template - - - 0.0000000000000000000000000000000000000001568 152.0
HFD3_k127_5279525_2 Pyridoxal-dependent decarboxylase conserved domain K01634,K18933 - 4.1.1.11,4.1.1.25,4.1.2.27 3.383e-194 625.0
HFD3_k127_5279525_20 protein phosphatase 2C domain protein - - - 0.000000000000000000000000000000000000005972 165.0
HFD3_k127_5279525_21 Cbs domain - - - 0.00000000000000000000000000000000000001195 148.0
HFD3_k127_5279525_22 Predicted membrane protein (DUF2231) - - - 0.00000000000000000000000000000125 128.0
HFD3_k127_5279525_23 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000001642 106.0
HFD3_k127_5279525_24 antisigma factor binding K04749 - - 0.000000002465 63.0
HFD3_k127_5279525_25 AMP binding - - - 0.000001029 57.0
HFD3_k127_5279525_26 antisigma factor binding - - - 0.00006611 54.0
HFD3_k127_5279525_27 Histidine kinase-like ATPase domain - - - 0.0003351 51.0
HFD3_k127_5279525_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 567.0
HFD3_k127_5279525_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 518.0
HFD3_k127_5279525_5 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 411.0
HFD3_k127_5279525_6 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 389.0
HFD3_k127_5279525_7 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 375.0
HFD3_k127_5279525_8 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 358.0
HFD3_k127_5279525_9 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 354.0
HFD3_k127_5332688_0 polysaccharide deacetylase - - - 0.000000000000000000000000000000001263 144.0
HFD3_k127_5392104_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006322 566.0
HFD3_k127_5392104_1 hydroperoxide reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 310.0
HFD3_k127_5392104_2 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000002543 224.0
HFD3_k127_5392104_3 MafB19-like deaminase K01485 - 3.5.4.1 0.0000000000000000000000000000000000000000000000000000001001 209.0
HFD3_k127_5392104_4 Nuclease-related domain - - - 0.000000000000000000000000000000000000000000000000002183 192.0
HFD3_k127_5445973_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1273.0
HFD3_k127_5445973_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 3.07e-277 864.0
HFD3_k127_5445973_10 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 471.0
HFD3_k127_5445973_11 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008238 458.0
HFD3_k127_5445973_12 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 427.0
HFD3_k127_5445973_13 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003653 426.0
HFD3_k127_5445973_14 Scramblase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007931 397.0
HFD3_k127_5445973_15 non-haem dioxygenase in morphine synthesis N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 391.0
HFD3_k127_5445973_16 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004329 398.0
HFD3_k127_5445973_17 ADP-glyceromanno-heptose 6-epimerase activity K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 369.0
HFD3_k127_5445973_18 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K01055 - 3.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 364.0
HFD3_k127_5445973_19 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 367.0
HFD3_k127_5445973_2 Elongation factor SelB, winged helix K03833 - - 1.768e-218 705.0
HFD3_k127_5445973_20 replication factor c K02341,K02343,K09384 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 341.0
HFD3_k127_5445973_21 Belongs to the NUDIX hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005755 292.0
HFD3_k127_5445973_22 Pfam:Zinicin_2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006402 299.0
HFD3_k127_5445973_23 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002548 290.0
HFD3_k127_5445973_24 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001487 284.0
HFD3_k127_5445973_25 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003701 278.0
HFD3_k127_5445973_26 type II secretion system protein E K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001885 284.0
HFD3_k127_5445973_27 spore germination - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000089 269.0
HFD3_k127_5445973_28 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001397 265.0
HFD3_k127_5445973_29 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000003096 243.0
HFD3_k127_5445973_3 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 5.939e-202 634.0
HFD3_k127_5445973_30 Anion-transporting ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000005023 244.0
HFD3_k127_5445973_31 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000009002 219.0
HFD3_k127_5445973_32 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000001369 214.0
HFD3_k127_5445973_33 - - - - 0.00000000000000000000000000000000000000000000000000000000002019 213.0
HFD3_k127_5445973_34 Pyridoxamine 5-phosphate - - - 0.000000000000000000000000000000000000000000000000000000002603 202.0
HFD3_k127_5445973_35 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000005082 193.0
HFD3_k127_5445973_36 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000008224 196.0
HFD3_k127_5445973_38 helix_turn _helix lactose operon repressor K02525,K02529 - - 0.0000000000000000000000000000000000000000000000181 185.0
HFD3_k127_5445973_39 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000004344 169.0
HFD3_k127_5445973_4 ACT domain K00928 - 2.7.2.4 7.771e-202 634.0
HFD3_k127_5445973_40 DNA-binding transcription factor activity K04096,K20421 - 2.1.1.303 0.0000000000000000000000000000000000000009978 153.0
HFD3_k127_5445973_41 MazG nucleotide pyrophosphohydrolase domain - - - 0.000000000000000000000000000000000001631 148.0
HFD3_k127_5445973_42 Type II secretion system (T2SS), protein F K12511 - - 0.00000000000000000000000000005838 133.0
HFD3_k127_5445973_43 Major facilitator Superfamily - - - 0.000000000000000000000000009421 124.0
HFD3_k127_5445973_44 - - - - 0.000000000000000000000005635 113.0
HFD3_k127_5445973_45 Putative zinc-finger - - - 0.0000000000000000000002689 98.0
HFD3_k127_5445973_46 unsaturated chondroitin disaccharide hydrolase activity K15532 - 3.2.1.172 0.0000000000000000000529 105.0
HFD3_k127_5445973_47 - - - - 0.0000000000000000005916 98.0
HFD3_k127_5445973_48 PFAM TadE family protein - - - 0.000000000000006211 79.0
HFD3_k127_5445973_49 Type ii secretion system K12510 - - 0.000000000002955 76.0
HFD3_k127_5445973_5 pyrroloquinoline quinone binding - - - 7.505e-201 651.0
HFD3_k127_5445973_50 Belongs to the anti-sigma-factor antagonist family - - - 0.000006298 53.0
HFD3_k127_5445973_6 MMPL family K06994 - - 2.531e-198 649.0
HFD3_k127_5445973_7 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 4.521e-198 625.0
HFD3_k127_5445973_8 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 GO:0003674,GO:0003824,GO:0004073,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006133 535.0
HFD3_k127_5445973_9 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 515.0
HFD3_k127_5459209_0 Protein of unknown function (DUF512) - - - 2.706e-215 676.0
HFD3_k127_5459209_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 1.715e-199 627.0
HFD3_k127_5459209_2 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 4.073e-195 625.0
HFD3_k127_5459209_3 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000659 518.0
HFD3_k127_5459209_4 FMN binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004567 269.0
HFD3_k127_5459209_5 - - - - 0.000000000000000000000000001658 116.0
HFD3_k127_5459209_6 Transglutaminase-like superfamily - - - 0.000000000000004643 82.0
HFD3_k127_5492351_0 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 0.0 1065.0
HFD3_k127_5492351_1 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0 1021.0
HFD3_k127_5492351_10 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009096 560.0
HFD3_k127_5492351_11 geranylgeranyl reductase activity K00313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009066 541.0
HFD3_k127_5492351_12 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007331 508.0
HFD3_k127_5492351_13 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004971 513.0
HFD3_k127_5492351_14 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000357 520.0
HFD3_k127_5492351_15 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 505.0
HFD3_k127_5492351_16 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005859 481.0
HFD3_k127_5492351_17 Belongs to the N(4) N(6)-methyltransferase family K00571,K00590 - 2.1.1.113,2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 464.0
HFD3_k127_5492351_18 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 431.0
HFD3_k127_5492351_19 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003237 396.0
HFD3_k127_5492351_2 von Willebrand factor (vWF) type A domain - - - 5.1e-320 990.0
HFD3_k127_5492351_20 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 354.0
HFD3_k127_5492351_21 Glycosyl transferase family group 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 348.0
HFD3_k127_5492351_22 succinate dehydrogenase K00241 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006486 328.0
HFD3_k127_5492351_23 Protein of unknown function (DUF418) K07148 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 315.0
HFD3_k127_5492351_24 Alanine racemase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 312.0
HFD3_k127_5492351_25 Neutral zinc metallopeptidase K07054 GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 311.0
HFD3_k127_5492351_26 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001093 277.0
HFD3_k127_5492351_27 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005813 274.0
HFD3_k127_5492351_28 purine-nucleoside phosphorylase K00772,K03784 - 2.4.2.1,2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000004948 264.0
HFD3_k127_5492351_29 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000143 246.0
HFD3_k127_5492351_3 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 9.493e-310 962.0
HFD3_k127_5492351_30 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000003912 235.0
HFD3_k127_5492351_31 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000001377 227.0
HFD3_k127_5492351_32 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001591 229.0
HFD3_k127_5492351_33 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000149 233.0
HFD3_k127_5492351_34 Pfam SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000002088 222.0
HFD3_k127_5492351_35 FMN binding - - - 0.000000000000000000000000000000000000000000000003963 181.0
HFD3_k127_5492351_36 SCP-2 sterol transfer family - - - 0.00000000000000000000000000000000000000000000001606 173.0
HFD3_k127_5492351_37 Domain of unknown function (DUF4395) - - - 0.00000000000000000000000000000000000000000000344 171.0
HFD3_k127_5492351_38 Psort location Cytoplasmic, score K03855 - - 0.00000000000000000000000000000000000000001918 162.0
HFD3_k127_5492351_39 Domain of unknown function (DUF3291) - - - 0.000000000000000000000000000000000000005165 156.0
HFD3_k127_5492351_4 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.585e-291 914.0
HFD3_k127_5492351_40 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000000000000000000000000006377 154.0
HFD3_k127_5492351_41 PFAM Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000001003 145.0
HFD3_k127_5492351_43 Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000004949 140.0
HFD3_k127_5492351_45 beta-glucosidase activity K00067,K05350 - 1.1.1.133,3.2.1.21 0.0000000000000000000000000000000894 137.0
HFD3_k127_5492351_46 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.00000000000000000000000000001904 125.0
HFD3_k127_5492351_47 Domain of unknown function (DUF4349) - - - 0.0000000000000000000000000001277 129.0
HFD3_k127_5492351_48 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.000000000000000000000000001053 125.0
HFD3_k127_5492351_5 beta-mannosidase K01192,K15855 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005576,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044238,GO:0071704,GO:1901575 3.2.1.165,3.2.1.25 2.022e-248 787.0
HFD3_k127_5492351_50 helix_turn_helix, cAMP Regulatory protein - - - 0.000000000000000000001731 102.0
HFD3_k127_5492351_52 DNA-templated transcription, initiation K03088 - - 0.000000000000000464 88.0
HFD3_k127_5492351_54 Acetyltransferase - - - 0.000000000004628 76.0
HFD3_k127_5492351_6 Mg-chelatase subunit ChlI K03405 - 6.6.1.1 1.08e-232 727.0
HFD3_k127_5492351_7 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 6.69e-223 700.0
HFD3_k127_5492351_8 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 588.0
HFD3_k127_5492351_9 Belongs to the xylose isomerase family K01805 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575 5.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 587.0
HFD3_k127_5513159_0 Bacterial extracellular solute-binding protein K17329 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 385.0
HFD3_k127_5513159_1 ROK family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 327.0
HFD3_k127_5513159_2 Cbs domain - - - 0.000000000000000001063 91.0
HFD3_k127_5520951_0 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 587.0
HFD3_k127_5520951_1 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 533.0
HFD3_k127_5520951_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008492 442.0
HFD3_k127_5520951_3 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 433.0
HFD3_k127_5520951_4 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 409.0
HFD3_k127_5520951_5 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008248 375.0
HFD3_k127_5520951_6 Belongs to the UPF0301 (AlgH) family K07735 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000001725 224.0
HFD3_k127_5520951_7 Regulates arginine biosynthesis genes K03402 - - 0.000000000000000000000000000000000000000000000000000000001038 211.0
HFD3_k127_5520951_8 Methylpurine-DNA glycosylase (MPG) K03652 - 3.2.2.21 0.0000000000000000000000000000000000000006716 161.0
HFD3_k127_5520951_9 5'-3' exonuclease, C-terminal SAM fold - - - 0.000000000003756 71.0
HFD3_k127_5547059_0 Sigma-70 region 2 - - - 0.0000000000000000000000000000003783 131.0
HFD3_k127_5547059_1 - - - - 0.000000000000000000000000001007 125.0
HFD3_k127_5552303_0 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - 0.0 1221.0
HFD3_k127_5552303_1 ATPase family associated with various cellular activities (AAA) K01338 - 3.4.21.53 0.0 1023.0
HFD3_k127_5552303_10 Penicillin binding protein transpeptidase domain K05364 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 532.0
HFD3_k127_5552303_11 Reductase C-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 462.0
HFD3_k127_5552303_12 Enoyl-(Acyl carrier protein) reductase K00034 - 1.1.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 392.0
HFD3_k127_5552303_13 Pectinacetylesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 372.0
HFD3_k127_5552303_14 Protein of unknown function (DUF3048) C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 373.0
HFD3_k127_5552303_15 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003887 355.0
HFD3_k127_5552303_16 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 332.0
HFD3_k127_5552303_17 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005497 323.0
HFD3_k127_5552303_18 Arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000743 306.0
HFD3_k127_5552303_19 Peptidase C26 K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006117 297.0
HFD3_k127_5552303_2 Glycogen debranching enzyme N terminal - - - 7.423e-224 716.0
HFD3_k127_5552303_20 Aminotransferase class-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001244 292.0
HFD3_k127_5552303_21 Protein of unknown function (DUF2662) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003079 283.0
HFD3_k127_5552303_22 Hypothetical methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000206 279.0
HFD3_k127_5552303_23 6-phosphogluconolactonase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001349 285.0
HFD3_k127_5552303_24 SpoU rRNA Methylase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001478 246.0
HFD3_k127_5552303_25 Sigma factor PP2C-like phosphatases K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000005673 254.0
HFD3_k127_5552303_26 Two component transcriptional regulator, LuxR family - - - 0.000000000000000000000000000000000000000000000000000000000000000001933 233.0
HFD3_k127_5552303_27 DNA repair protein - - - 0.0000000000000000000000000000000000000000000000000000000000007721 219.0
HFD3_k127_5552303_28 Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP K01004 - 2.7.8.24 0.0000000000000000000000000000000000000003573 162.0
HFD3_k127_5552303_29 Forkhead associated domain - - - 0.00000000000000000000000000000000000001019 154.0
HFD3_k127_5552303_3 GMC oxidoreductase - - - 5.966e-217 693.0
HFD3_k127_5552303_30 - - - - 0.00000000000000000000000000000000004306 143.0
HFD3_k127_5552303_31 - - - - 0.00000000000000000000000000000000005807 136.0
HFD3_k127_5552303_32 DNA-binding transcription factor activity K18996 - - 0.0000000000000000000000000000000007799 134.0
HFD3_k127_5552303_33 - - - - 0.000000000000000000000000000000004961 144.0
HFD3_k127_5552303_35 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000005548 90.0
HFD3_k127_5552303_36 Pkd domain containing protein - - - 0.00000000000001889 87.0
HFD3_k127_5552303_37 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.000000000000134 72.0
HFD3_k127_5552303_4 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 618.0
HFD3_k127_5552303_5 AMP-binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 607.0
HFD3_k127_5552303_6 Cell cycle protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 602.0
HFD3_k127_5552303_7 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 573.0
HFD3_k127_5552303_8 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 537.0
HFD3_k127_5552303_9 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 538.0
HFD3_k127_5590850_0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000576 270.0
HFD3_k127_5590850_1 PFAM Phospholipid glycerol acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000003892 219.0
HFD3_k127_5590850_2 Fasciclin - GO:0005575,GO:0005576,GO:0005615,GO:0005623,GO:0005886,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043207,GO:0044403,GO:0044419,GO:0044421,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071944,GO:0075136 - 0.00000000000000000000000000000000000000000000000000006725 193.0
HFD3_k127_5590850_3 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.0000000000000000000000000000000000000001379 165.0
HFD3_k127_5590850_4 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.00000000000000000000000000000000003651 151.0
HFD3_k127_5590850_5 Putative collagen-binding domain of a collagenase - - - 0.000000000000000000114 103.0
HFD3_k127_5590850_6 Anti-sigma-K factor rskA - - - 0.000000000000000000299 95.0
HFD3_k127_5611359_0 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 482.0
HFD3_k127_5611359_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006872 448.0
HFD3_k127_5611359_10 haloacid dehalogenase-like hydrolase K18697 - 3.1.3.27 0.000000000000000000000000000000000000000000000001067 182.0
HFD3_k127_5611359_11 Acyltransferase - - - 0.00000000000000000000000000007965 132.0
HFD3_k127_5611359_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 446.0
HFD3_k127_5611359_3 Prephenate dehydrogenase K00210,K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 434.0
HFD3_k127_5611359_4 RNA pseudouridylate synthase K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009241 359.0
HFD3_k127_5611359_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 345.0
HFD3_k127_5611359_6 UbiA prenyltransferase family K14136 - 2.4.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 319.0
HFD3_k127_5611359_7 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008233 289.0
HFD3_k127_5611359_8 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001739 258.0
HFD3_k127_5611359_9 FAD binding domain K16653 - 1.1.98.3 0.0000000000000000000000000000000000000000000000000000000004337 215.0
HFD3_k127_5617826_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.385e-302 942.0
HFD3_k127_5617826_1 Luciferase-like monooxygenase K14733 - 1.14.13.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 593.0
HFD3_k127_5617826_10 - - - - 0.000000000000000000000000000000000000000000000000000006082 193.0
HFD3_k127_5617826_11 acetyltransferase K01246 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0044424,GO:0044464 3.2.2.20 0.000000000000000000000000000000000942 136.0
HFD3_k127_5617826_12 SnoaL-like domain - - - 0.0000000000000000000000000000000488 132.0
HFD3_k127_5617826_2 ABC-type polar amino acid transport system ATPase component K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 383.0
HFD3_k127_5617826_3 Insulinase (Peptidase family M16) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 340.0
HFD3_k127_5617826_4 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 335.0
HFD3_k127_5617826_5 Polar amino acid ABC transporter K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003998 282.0
HFD3_k127_5617826_6 with chaperone activity, ATP-binding subunit K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004487 269.0
HFD3_k127_5617826_7 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009405,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0015036,GO:0016209,GO:0016491,GO:0016667,GO:0016684,GO:0019725,GO:0020012,GO:0030312,GO:0030682,GO:0042221,GO:0042592,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071944,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000006065 222.0
HFD3_k127_5617826_8 Bacterial periplasmic substrate-binding proteins K02030 - - 0.000000000000000000000000000000000000000000000000000000005139 209.0
HFD3_k127_5631129_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009223 297.0
HFD3_k127_5631129_1 - - - - 0.000006361 48.0
HFD3_k127_5638685_0 PFAM Protein kinase domain K12132 - 2.7.11.1 0.000000000000008579 85.0
HFD3_k127_5664114_0 cytochrome p450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 335.0
HFD3_k127_5664114_1 Domain of unknown function (DUF1330) - - - 0.00000000000000000007464 92.0
HFD3_k127_5664114_2 WD-40 repeat - - - 0.000000005514 59.0
HFD3_k127_5664114_3 Transcriptional regulator - - - 0.00000004277 57.0
HFD3_k127_5664114_4 - - - - 0.00004662 53.0
HFD3_k127_5668190_0 Glycine cleavage system P-protein K00281,K00283 - 1.4.4.2 0.0 1315.0
HFD3_k127_5668190_1 Glycine cleavage T-protein C-terminal barrel domain K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 474.0
HFD3_k127_5668190_10 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000001287 253.0
HFD3_k127_5668190_11 pfkB family carbohydrate kinase K00882 - 2.7.1.56 0.000000000000000000000000000000000000000000000000000000000000001028 230.0
HFD3_k127_5668190_12 Copper amine oxidase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000001013 218.0
HFD3_k127_5668190_13 Histidine triad (Hit) protein K02503 - - 0.000000000000000000000000000000000000000000000000000001438 195.0
HFD3_k127_5668190_15 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000006138 179.0
HFD3_k127_5668190_16 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000076 179.0
HFD3_k127_5668190_17 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000001042 167.0
HFD3_k127_5668190_18 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000001178 168.0
HFD3_k127_5668190_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 325.0
HFD3_k127_5668190_21 diguanylate cyclase - - - 0.000000000000000000000000000000005157 144.0
HFD3_k127_5668190_22 Survival protein SurE K03787 - 3.1.3.5 0.00000000000000000000000000000009631 134.0
HFD3_k127_5668190_24 - - - - 0.0000000000002985 81.0
HFD3_k127_5668190_25 - - - - 0.0000000351 58.0
HFD3_k127_5668190_3 SOS response associated peptidase (SRAP) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 297.0
HFD3_k127_5668190_4 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 291.0
HFD3_k127_5668190_5 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005161 274.0
HFD3_k127_5668190_6 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005518 261.0
HFD3_k127_5668190_7 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001844 239.0
HFD3_k127_5668190_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.0000000000000000000000000000000000000000000000000000000000000000001494 235.0
HFD3_k127_5668190_9 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000000000000000000000000000000000000008921 233.0
HFD3_k127_5711603_0 helicase activity - - - 4.479e-245 769.0
HFD3_k127_5711603_1 homoserine dehydrogenase - - - 2.215e-213 670.0
HFD3_k127_5711603_10 Putative serine dehydratase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009614 382.0
HFD3_k127_5711603_11 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009679 377.0
HFD3_k127_5711603_12 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 382.0
HFD3_k127_5711603_13 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006734 372.0
HFD3_k127_5711603_14 Nucleotidyl transferase K00978 - 2.7.7.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 364.0
HFD3_k127_5711603_15 Belongs to the glycosyltransferase 26 family K05946 - 2.4.1.187 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006974 334.0
HFD3_k127_5711603_16 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 300.0
HFD3_k127_5711603_17 PFAM glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008599 301.0
HFD3_k127_5711603_18 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 300.0
HFD3_k127_5711603_19 Belongs to the sigma-70 factor family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002143 271.0
HFD3_k127_5711603_2 Pyridoxal-phosphate dependent enzyme K21148 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 534.0
HFD3_k127_5711603_20 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000257 250.0
HFD3_k127_5711603_21 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001297 250.0
HFD3_k127_5711603_22 Conserved hypothetical protein (DUF2461) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006731 248.0
HFD3_k127_5711603_23 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000006366 248.0
HFD3_k127_5711603_24 Sortase family K07284 - 3.4.22.70 0.0000000000000000000000000000000000000000000000000000000000000000002449 250.0
HFD3_k127_5711603_25 Fibronectin type 3 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000338 257.0
HFD3_k127_5711603_26 O-acyltransferase activity K00661 - 2.3.1.79 0.000000000000000000000000000000000000000000000000000000006631 204.0
HFD3_k127_5711603_27 Trehalose utilisation - - - 0.0000000000000000000000000000000000000000000000000000719 216.0
HFD3_k127_5711603_28 extracellular polysaccharide biosynthetic process K16692,K20998 - - 0.00000000000000000000000000000000000000000000000000161 196.0
HFD3_k127_5711603_29 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000009276 188.0
HFD3_k127_5711603_3 protoporphyrinogen oxidase activity K01854 - 5.4.99.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 494.0
HFD3_k127_5711603_30 PFAM glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000007093 192.0
HFD3_k127_5711603_31 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.000000000000000000000000000000000000000000002636 170.0
HFD3_k127_5711603_32 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.000000000000000000000000000000000000000001496 161.0
HFD3_k127_5711603_33 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000003408 161.0
HFD3_k127_5711603_34 Putative collagen-binding domain of a collagenase - - - 0.000000000000000000000000000000000000000004471 175.0
HFD3_k127_5711603_35 PFAM FecR protein K07279 - - 0.0000000000000000000000000000000000000000211 175.0
HFD3_k127_5711603_36 EamA-like transporter family - - - 0.0000000000000000000000000000000000000003359 161.0
HFD3_k127_5711603_37 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000005081 161.0
HFD3_k127_5711603_38 metallocarboxypeptidase activity K14054 - - 0.0000000000000000000000000000000000000006221 160.0
HFD3_k127_5711603_39 protein tyrosine kinase activity K20998 - - 0.0000000000000000000000000000000000000006787 159.0
HFD3_k127_5711603_4 -O-antigen K02847,K02849,K21003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 452.0
HFD3_k127_5711603_40 JAB/MPN domain K21140 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006508,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016787,GO:0019344,GO:0019538,GO:0019752,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.13.1.6 0.000000000000000000000000000000000000001263 152.0
HFD3_k127_5711603_41 GMC oxidoreductase - - - 0.00000000000000000000000000000000000001292 163.0
HFD3_k127_5711603_43 PFAM transferase hexapeptide repeat containing protein K00661 - 2.3.1.79 0.0000000000000000000000000000000000005639 146.0
HFD3_k127_5711603_44 polysaccharide biosynthetic process - - - 0.00000000000000000000000000000000002834 151.0
HFD3_k127_5711603_45 Aldo/keto reductase family K19265 - - 0.00000000000000000000000000000002479 139.0
HFD3_k127_5711603_46 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000005658 141.0
HFD3_k127_5711603_47 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000009515 133.0
HFD3_k127_5711603_48 - - - - 0.0000000000000000000000000000323 127.0
HFD3_k127_5711603_49 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000001813 111.0
HFD3_k127_5711603_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008698 426.0
HFD3_k127_5711603_50 Fibronectin type 3 domain K01218 - 3.2.1.78 0.0000000000000000000008265 113.0
HFD3_k127_5711603_51 Glycosyl transferases group 1 - - - 0.00000000000000000008073 103.0
HFD3_k127_5711603_52 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000001314 82.0
HFD3_k127_5711603_53 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0000000000000633 84.0
HFD3_k127_5711603_54 dioxygenase activity - - - 0.0000000000003129 79.0
HFD3_k127_5711603_55 - - - - 0.00001312 54.0
HFD3_k127_5711603_6 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 422.0
HFD3_k127_5711603_7 Protein of unknown function (DUF1349) K01802,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 453.0
HFD3_k127_5711603_8 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 386.0
HFD3_k127_5711603_9 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 393.0
HFD3_k127_5714401_0 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 1.006e-218 688.0
HFD3_k127_5714401_1 Belongs to the GPI family K01810 GO:0003674,GO:0003824,GO:0004347,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 1.333e-213 675.0
HFD3_k127_5714401_10 Glycosyl transferase, family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 344.0
HFD3_k127_5714401_11 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006615 336.0
HFD3_k127_5714401_12 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007082 332.0
HFD3_k127_5714401_13 WYL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 314.0
HFD3_k127_5714401_14 transcriptional regulator K13573 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005671 310.0
HFD3_k127_5714401_15 Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005989 301.0
HFD3_k127_5714401_17 neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002535 289.0
HFD3_k127_5714401_18 PFAM Wyosine base formation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000852 276.0
HFD3_k127_5714401_19 RarD protein K05786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004132 276.0
HFD3_k127_5714401_2 ATPase related to phosphate starvation-inducible protein PhoH K07175 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 615.0
HFD3_k127_5714401_20 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000003035 267.0
HFD3_k127_5714401_21 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000007975 218.0
HFD3_k127_5714401_22 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000008409 217.0
HFD3_k127_5714401_23 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000345 202.0
HFD3_k127_5714401_24 Guanylyl transferase CofC like K14941 - 2.7.7.68 0.00000000000000000000000000000000000000000000000000002484 196.0
HFD3_k127_5714401_25 Phosphoglucose isomerase K01810 - 5.3.1.9 0.0000000000000000000000000000000000000000000000009788 186.0
HFD3_k127_5714401_26 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.00000000000000000000000000000000000000000000003024 181.0
HFD3_k127_5714401_27 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.00000000000000000000000000000000000000000000003149 187.0
HFD3_k127_5714401_28 Periplasmic binding protein - - - 0.0000000000000000000000000000000000000004099 166.0
HFD3_k127_5714401_29 Phosphotransferase enzyme family K18817 - 2.7.1.163 0.0000000000000000000000000000000000001517 153.0
HFD3_k127_5714401_3 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 GO:0000271,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901576 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 592.0
HFD3_k127_5714401_30 - - - - 0.000000000000000000000000000000248 127.0
HFD3_k127_5714401_31 Domain of unknown function (DUF305) - - - 0.00000000000000000000000000005349 126.0
HFD3_k127_5714401_32 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - 0.00000000000000000000000004068 111.0
HFD3_k127_5714401_34 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.000000000006002 65.0
HFD3_k127_5714401_35 Multicopper oxidase - - - 0.00000000001182 73.0
HFD3_k127_5714401_36 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000008757 61.0
HFD3_k127_5714401_37 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0004005 46.0
HFD3_k127_5714401_4 Cys/Met metabolism PLP-dependent enzyme K01739 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009844 503.0
HFD3_k127_5714401_5 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 494.0
HFD3_k127_5714401_6 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000729 475.0
HFD3_k127_5714401_7 Ppx GppA phosphatase K01524 GO:0003674,GO:0003824,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 457.0
HFD3_k127_5714401_8 Methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 426.0
HFD3_k127_5714401_9 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 388.0
HFD3_k127_5801620_0 Nucleotidyltransferase domain K07075 - - 0.0000000000000001211 81.0
HFD3_k127_5801620_2 Protein of unknown function DUF86 - - - 0.0000000000004319 74.0
HFD3_k127_5801620_3 Clp amino terminal domain, pathogenicity island component - - - 0.0002299 47.0
HFD3_k127_5834199_0 - - - - 0.0000000000009162 79.0
HFD3_k127_5842274_0 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007117 428.0
HFD3_k127_5842274_1 lactoylglutathione lyase activity - - - 0.000000000000000000000001781 107.0
HFD3_k127_5842274_2 Transcriptional regulator - - - 0.00000000008252 67.0
HFD3_k127_5850130_0 Fe-S oxidoreductase - - - 6.38e-283 887.0
HFD3_k127_5850130_1 lactoylglutathione lyase activity - - - 1.266e-210 660.0
HFD3_k127_5850130_10 Glycine cleavage H-protein K02437 - - 0.000000000000000000000000000000000000000000000000000000000000000386 223.0
HFD3_k127_5850130_11 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein - - - 0.000000000000000000000000000000000000000000000000000005011 194.0
HFD3_k127_5850130_12 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000000000004194 190.0
HFD3_k127_5850130_13 Transposase K07493 - - 0.0000000000000000000000000000001108 124.0
HFD3_k127_5850130_14 Transcriptional regulator, arsR family - - - 0.0000000000000000000000000000001146 126.0
HFD3_k127_5850130_15 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000001343 133.0
HFD3_k127_5850130_16 - - - - 0.0000000000000000000000001193 111.0
HFD3_k127_5850130_17 sulfur carrier activity - - - 0.0000000000000000000000007167 105.0
HFD3_k127_5850130_18 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000001731 102.0
HFD3_k127_5850130_19 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000003564 85.0
HFD3_k127_5850130_2 Elongator protein 3, MiaB family, Radical SAM K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006553 528.0
HFD3_k127_5850130_20 Elongator protein 3, MiaB family, Radical SAM K09711 - - 0.00000000000000004371 81.0
HFD3_k127_5850130_21 YibE F family protein - - - 0.000000000001271 72.0
HFD3_k127_5850130_22 - - - - 0.0000003162 63.0
HFD3_k127_5850130_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 467.0
HFD3_k127_5850130_4 Electron transfer flavoprotein alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 366.0
HFD3_k127_5850130_5 Lipoate-protein ligase K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 358.0
HFD3_k127_5850130_6 Electron transfer flavoprotein domain K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000667 282.0
HFD3_k127_5850130_7 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001747 265.0
HFD3_k127_5850130_8 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004019 258.0
HFD3_k127_5850130_9 DsrE/DsrF-like family K07092 - - 0.00000000000000000000000000000000000000000000000000000000000000001509 228.0
HFD3_k127_5854211_0 Protein synonym acyl-CoA synthetase K01897 - 6.2.1.3 5.853e-257 813.0
HFD3_k127_5854211_1 FAD dependent oxidoreductase - - - 3.61e-214 676.0
HFD3_k127_5854211_10 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 292.0
HFD3_k127_5854211_11 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000005514 265.0
HFD3_k127_5854211_12 PFAM Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000001727 185.0
HFD3_k127_5854211_13 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000006972 141.0
HFD3_k127_5854211_14 Rhodanese Homology Domain K01011,K21028 - 2.8.1.1,2.8.1.11,2.8.1.2 0.0000000000003546 73.0
HFD3_k127_5854211_16 FMN binding - - - 0.0000008077 60.0
HFD3_k127_5854211_2 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 7.796e-212 669.0
HFD3_k127_5854211_3 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007509 544.0
HFD3_k127_5854211_4 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 516.0
HFD3_k127_5854211_5 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005935 489.0
HFD3_k127_5854211_6 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008419 460.0
HFD3_k127_5854211_7 cytosine deaminase K01485 - 3.5.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 391.0
HFD3_k127_5854211_8 Creatininase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000043 347.0
HFD3_k127_5854211_9 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005293 326.0
HFD3_k127_5854485_0 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 5.39e-279 888.0
HFD3_k127_5854485_1 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001237 296.0
HFD3_k127_5854485_2 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001774 262.0
HFD3_k127_5854485_3 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000002433 179.0
HFD3_k127_5854485_4 dipeptide transport K02035 - - 0.000000000000000000000000000000248 127.0
HFD3_k127_586439_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 5e-324 1002.0
HFD3_k127_586439_1 Seryl-tRNA synthetase N-terminal domain K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 570.0
HFD3_k127_586439_10 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000003471 233.0
HFD3_k127_586439_11 - - - - 0.00000000000000000000000000000000000000000000000000000001303 219.0
HFD3_k127_586439_12 Cytochrome c biogenesis protein transmembrane region - - - 0.000000000000000000000000000000000000000000000000000006268 206.0
HFD3_k127_586439_13 Thioesterase K07107 - - 0.000000000000000000000000000000000000000000000000002911 186.0
HFD3_k127_586439_14 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000001475 188.0
HFD3_k127_586439_15 ATP-dependent Clp protease adaptor protein ClpS K06891 - - 0.00000000000000000000000000000000000003007 149.0
HFD3_k127_586439_16 Redoxin - - - 0.0000000000000000000000000000000000006837 147.0
HFD3_k127_586439_17 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA K18958 GO:0001101,GO:0008150,GO:0010033,GO:0033993,GO:0042221,GO:0046677,GO:0050896,GO:0070542,GO:1901700 - 0.0000000000000000000000000000000003001 140.0
HFD3_k127_586439_19 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.000000000000000000000000003245 114.0
HFD3_k127_586439_2 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 495.0
HFD3_k127_586439_3 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02298 - 1.10.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 447.0
HFD3_k127_586439_4 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007591 398.0
HFD3_k127_586439_5 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) K02862 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009956 353.0
HFD3_k127_586439_6 Cytochrome c oxidase subunit III K02276,K02299 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 306.0
HFD3_k127_586439_7 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002558 271.0
HFD3_k127_586439_8 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0010181,GO:0016491,GO:0016614,GO:0016899,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032553,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0042803,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000009527 269.0
HFD3_k127_586439_9 Replication protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004512 256.0
HFD3_k127_5870391_0 beta-1,4-mannooligosaccharide phosphorylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005639 478.0
HFD3_k127_5881294_0 Dihydropyrimidinase K01464 - 3.5.2.2 1.396e-218 687.0
HFD3_k127_5881294_1 ATP-dependent helicase K03579 - 3.6.4.13 3.328e-206 681.0
HFD3_k127_5881294_10 - - - - 0.000000000000000000000000000000000000000000000000000000006986 203.0
HFD3_k127_5881294_11 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000000000000000005337 159.0
HFD3_k127_5881294_12 Papain family cysteine protease - - - 0.0000000000000000001969 99.0
HFD3_k127_5881294_13 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000004798 100.0
HFD3_k127_5881294_14 Methyltransferase domain - - - 0.000000000000000001336 95.0
HFD3_k127_5881294_2 Catalyzes the reversible hydration of fumarate to (S)- malate K01676,K01678,K03780 - 4.2.1.2,4.2.1.32 1.056e-200 631.0
HFD3_k127_5881294_3 Carbon-nitrogen hydrolase K01431 - 3.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 498.0
HFD3_k127_5881294_4 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 469.0
HFD3_k127_5881294_5 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005805 302.0
HFD3_k127_5881294_7 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001836 254.0
HFD3_k127_5881294_8 Belongs to the DegT DnrJ EryC1 family K13310 - 2.6.1.106 0.00000000000000000000000000000000000000000000000000000000000000003307 236.0
HFD3_k127_5881294_9 Initiation factor 2 subunit family - - - 0.000000000000000000000000000000000000000000000000000000002536 209.0
HFD3_k127_5910227_0 Fibronectin type iii domain protein - - - 0.0 1506.0
HFD3_k127_5910227_1 haloacid dehalogenase-like hydrolase - - - 0.0 1127.0
HFD3_k127_5910227_10 PFAM Alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 304.0
HFD3_k127_5910227_11 transcriptional regulator K09017 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007705 251.0
HFD3_k127_5910227_12 AsnC family transcriptional regulator K03719 - - 0.0000000000000000000000000000000000000000000000000001062 191.0
HFD3_k127_5910227_13 Pfam:Pyridox_oxidase - - - 0.000000000000000000000000000000000000000000000000007591 186.0
HFD3_k127_5910227_2 Domain of unknown function (DUF2088) - - - 7.005e-286 885.0
HFD3_k127_5910227_3 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000924 556.0
HFD3_k127_5910227_4 cytochrome p450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 523.0
HFD3_k127_5910227_5 Mur ligase family, glutamate ligase domain K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006374 445.0
HFD3_k127_5910227_6 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 425.0
HFD3_k127_5910227_7 D-ala D-ala ligase N-terminus K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 401.0
HFD3_k127_5910227_8 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 395.0
HFD3_k127_5910227_9 Belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005322 336.0
HFD3_k127_5946211_0 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 501.0
HFD3_k127_5946211_1 Papain family cysteine protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 383.0
HFD3_k127_5946211_10 helix_turn_helix, Arsenical Resistance Operon Repressor - GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043254,GO:0044087,GO:0044212,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000266 136.0
HFD3_k127_5946211_11 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000001294 119.0
HFD3_k127_5946211_12 - - - - 0.000000000000000000004979 105.0
HFD3_k127_5946211_13 Pfam Secreted repeat of K19519 - - 0.00000000000000001026 91.0
HFD3_k127_5946211_14 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.00000000000000178 78.0
HFD3_k127_5946211_15 Chagasin family peptidase inhibitor I42 - - - 0.00000004586 59.0
HFD3_k127_5946211_2 methyltransferase K15942 - 2.1.1.288 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009682 298.0
HFD3_k127_5946211_3 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000000000000000000000000009208 225.0
HFD3_k127_5946211_4 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000005014 219.0
HFD3_k127_5946211_5 - - - - 0.0000000000000000000000000000000000000000000000000000003601 202.0
HFD3_k127_5946211_6 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000342 188.0
HFD3_k127_5946211_7 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000242 181.0
HFD3_k127_5946211_8 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000714 175.0
HFD3_k127_5946211_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000458 158.0
HFD3_k127_6024735_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 1.469e-304 967.0
HFD3_k127_6024735_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 2.073e-295 918.0
HFD3_k127_6024735_10 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 518.0
HFD3_k127_6024735_11 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 482.0
HFD3_k127_6024735_12 ABC-type Fe3 transport system permease component K02011,K02063 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 486.0
HFD3_k127_6024735_13 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 471.0
HFD3_k127_6024735_14 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006751 466.0
HFD3_k127_6024735_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007015 447.0
HFD3_k127_6024735_16 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 415.0
HFD3_k127_6024735_17 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009991 418.0
HFD3_k127_6024735_18 Enoyl-CoA hydratase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 370.0
HFD3_k127_6024735_19 Nucleotidyl transferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 367.0
HFD3_k127_6024735_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 7.985e-226 722.0
HFD3_k127_6024735_20 ABC transporter, periplasmic binding protein, thiB subfamily K02064 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 371.0
HFD3_k127_6024735_21 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 369.0
HFD3_k127_6024735_22 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 359.0
HFD3_k127_6024735_23 Cation efflux family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000699 341.0
HFD3_k127_6024735_24 inositol monophosphatase K01092,K05602 - 3.1.3.15,3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007503 322.0
HFD3_k127_6024735_25 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 306.0
HFD3_k127_6024735_26 NifU-like domain K07400 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009853 293.0
HFD3_k127_6024735_27 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008927 284.0
HFD3_k127_6024735_28 ABC transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000229 299.0
HFD3_k127_6024735_29 HNH nucleases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001089 289.0
HFD3_k127_6024735_3 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 2.904e-222 694.0
HFD3_k127_6024735_30 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003534 275.0
HFD3_k127_6024735_31 PAC2 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003189 289.0
HFD3_k127_6024735_32 dTDP-4-dehydrorhamnose reductase activity K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000001158 269.0
HFD3_k127_6024735_33 ACT domain K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000007044 266.0
HFD3_k127_6024735_34 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.00000000000000000000000000000000000000000000000000000000000000000000000002577 257.0
HFD3_k127_6024735_35 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000006315 250.0
HFD3_k127_6024735_36 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000001005 241.0
HFD3_k127_6024735_37 Belongs to the ABC transporter superfamily K02052,K02062 - - 0.00000000000000000000000000000000000000000000000000000000000000001858 230.0
HFD3_k127_6024735_38 - K09957 - - 0.0000000000000000000000000000000000000000000000000000000000000001425 240.0
HFD3_k127_6024735_39 Peroxiredoxin K04063 - - 0.00000000000000000000000000000000000000000000000000000000000001774 218.0
HFD3_k127_6024735_4 Putative modulator of DNA gyrase K03568 - - 5.061e-220 690.0
HFD3_k127_6024735_40 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000005895 205.0
HFD3_k127_6024735_41 CopC domain K07156,K14166 - - 0.0000000000000000000000000000000000000000002948 180.0
HFD3_k127_6024735_42 Cobinamide kinase / cobinamide phosphate guanyltransferase K02231 - 2.7.1.156,2.7.7.62 0.0000000000000000000000000000000000000000004707 162.0
HFD3_k127_6024735_43 PHP-associated - - - 0.0000000000000000000000000000000000000006372 158.0
HFD3_k127_6024735_44 Mycothiol maleylpyruvate isomerase N-terminal domain K16163 - 5.2.1.4 0.000000000000000000000000000000000000005452 153.0
HFD3_k127_6024735_45 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000006054 161.0
HFD3_k127_6024735_46 Major facilitator Superfamily - - - 0.000000000000000000000000000000003777 144.0
HFD3_k127_6024735_47 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000005778 120.0
HFD3_k127_6024735_49 PFAM Thiamin pyrophosphokinase, vitamin B1 binding domain K00949 - 2.7.6.2 0.00000000000000000000000629 109.0
HFD3_k127_6024735_5 Putative modulator of DNA gyrase K03592 - - 1.873e-210 662.0
HFD3_k127_6024735_50 Regulatory protein, FmdB family - - - 0.00000000000000000000004846 102.0
HFD3_k127_6024735_51 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000001637 105.0
HFD3_k127_6024735_53 Alpha/beta hydrolase family K03928 - 3.1.1.1 0.000000000000000286 89.0
HFD3_k127_6024735_54 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000002653 91.0
HFD3_k127_6024735_55 universal stress protein - - - 0.00000000000008173 79.0
HFD3_k127_6024735_56 AAA ATPase domain - - - 0.000000000001145 82.0
HFD3_k127_6024735_6 PFAM AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 606.0
HFD3_k127_6024735_7 Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 584.0
HFD3_k127_6024735_8 Cys/Met metabolism PLP-dependent enzyme K01739,K01740,K01761 - 2.5.1.48,2.5.1.49,4.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005546 531.0
HFD3_k127_6024735_9 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009017 523.0
HFD3_k127_6052008_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 5.548e-252 803.0
HFD3_k127_6052008_1 sequence-specific DNA binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 419.0
HFD3_k127_6052008_2 Cupin domain K08641,K11312 - 3.4.13.22 0.000000000000000000000000000000000000000000000005293 178.0
HFD3_k127_6052008_3 DinB superfamily - - - 0.00000000000000000000000000000000000000000000001571 179.0
HFD3_k127_6052008_4 dithiol-disulfide isomerase involved in polyketide biosynthesis - - - 0.000000000000000000000000000000000000000000002832 171.0
HFD3_k127_6052008_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000004832 153.0
HFD3_k127_6052008_6 - - - - 0.00000000000000000000000000000001244 132.0
HFD3_k127_6052008_7 Transcriptional regulator - - - 0.00000000000000000000000009201 109.0
HFD3_k127_6052008_8 C-terminal domain of 1-Cys peroxiredoxin - - - 0.000000001185 64.0
HFD3_k127_6133257_0 Salmonella virulence plasmid 65kDa B protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 582.0
HFD3_k127_6133257_1 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.000000000000000000000000000000000003111 161.0
HFD3_k127_6133257_2 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K01179,K01637 - 3.2.1.4,4.1.3.1 0.00000000000000000000002527 118.0
HFD3_k127_6133257_3 peptidase M36 K01417 - - 0.00000001625 69.0
HFD3_k127_6170516_0 Transposase K07486 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008058 474.0
HFD3_k127_6170516_1 Helix-turn-helix domain of transposase family ISL3 K07485 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000001114 75.0
HFD3_k127_6170516_2 Transposase - - - 0.0000000000001278 72.0
HFD3_k127_6240488_0 Adenylyl cyclase class-3 4 guanylyl cyclase - - - 1.299e-266 859.0
HFD3_k127_6240488_1 ATPase, P-type K12952 - - 1.839e-222 714.0
HFD3_k127_6240488_10 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000677 198.0
HFD3_k127_6240488_11 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000005619 168.0
HFD3_k127_6240488_12 ABC-2 family transporter protein - - - 0.000000000000000000000000000000000000000000005257 174.0
HFD3_k127_6240488_13 Oxidoreductase family, NAD-binding Rossmann fold K00010 - 1.1.1.18,1.1.1.369 0.00000000000000000000000000000000000000000006934 169.0
HFD3_k127_6240488_14 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000004239 151.0
HFD3_k127_6240488_15 Protein of unknown function (DUF1697) - - - 0.00000000000000000000000000000000000001356 151.0
HFD3_k127_6240488_16 - - - - 0.00000000000000000000000000000003773 132.0
HFD3_k127_6240488_17 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000002936 113.0
HFD3_k127_6240488_18 - - - - 0.0000000000000000003326 90.0
HFD3_k127_6240488_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 523.0
HFD3_k127_6240488_3 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007031 400.0
HFD3_k127_6240488_4 C-terminal domain of 1-Cys peroxiredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 387.0
HFD3_k127_6240488_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 391.0
HFD3_k127_6240488_6 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 381.0
HFD3_k127_6240488_7 Glycosylase K05522 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 342.0
HFD3_k127_6240488_8 Peptidoglycan-binding domain 1 protein K01227,K01448,K03791,K13277,K17733 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016787,GO:0017171,GO:0018104,GO:0019538,GO:0030203,GO:0030312,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044464,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 3.2.1.96,3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 333.0
HFD3_k127_6240488_9 ADP-ribose pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004539 267.0
HFD3_k127_6262456_0 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 2.117e-212 679.0
HFD3_k127_6262456_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009012 569.0
HFD3_k127_6262456_10 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007567 342.0
HFD3_k127_6262456_11 Protein of unknown function (DUF3500) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 341.0
HFD3_k127_6262456_12 Branched-chain amino acid transport K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 311.0
HFD3_k127_6262456_13 Branched-chain amino acid ATP-binding cassette transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001485 304.0
HFD3_k127_6262456_14 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008663 282.0
HFD3_k127_6262456_15 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000746 285.0
HFD3_k127_6262456_16 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007638 270.0
HFD3_k127_6262456_17 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000002233 267.0
HFD3_k127_6262456_18 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000002041 231.0
HFD3_k127_6262456_19 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000000003354 223.0
HFD3_k127_6262456_2 Glucose inhibited division protein A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005095 443.0
HFD3_k127_6262456_20 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000003853 237.0
HFD3_k127_6262456_21 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000004623 213.0
HFD3_k127_6262456_22 Glycoside-hydrolase family GH114 - - - 0.00000000000000000000000000000000000000000000000000000002527 212.0
HFD3_k127_6262456_23 oxidoreductase activity K07114 - - 0.000000000000000000000000000000000000000000000000000001289 206.0
HFD3_k127_6262456_24 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000000000000000000000000000000000003873 193.0
HFD3_k127_6262456_25 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000003691 200.0
HFD3_k127_6262456_26 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K20276 - - 0.00000000000000000000000000000000000000000000000000006018 214.0
HFD3_k127_6262456_27 GDP-mannose 4,6 dehydratase K21214 - - 0.0000000000000000000000000000000000000000000000000006775 197.0
HFD3_k127_6262456_28 Glycoside-hydrolase family GH114 - - - 0.00000000000000000000000000000000000000000000000000159 206.0
HFD3_k127_6262456_29 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000008539 179.0
HFD3_k127_6262456_3 epimerase dehydratase K01710,K08678,K21211 - 4.1.1.35,4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 429.0
HFD3_k127_6262456_30 SAF - - - 0.00000000000000000000000000000000000000000009673 168.0
HFD3_k127_6262456_31 LysM domain K12204 - - 0.0000000000000000000000000000000000000000002664 175.0
HFD3_k127_6262456_32 Inositol monophosphatase family K05602 - 3.1.3.15 0.0000000000000000000000000000000000000009905 169.0
HFD3_k127_6262456_33 protein domain, possibly involved in tellurite resistance - - - 0.0000000000000000000000000000000001761 137.0
HFD3_k127_6262456_35 - - - - 0.000000000000000000000001211 108.0
HFD3_k127_6262456_36 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000007799 96.0
HFD3_k127_6262456_37 cellulase activity - - - 0.000000000000003105 81.0
HFD3_k127_6262456_38 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.0000000000003273 74.0
HFD3_k127_6262456_39 - - - - 0.0007433 52.0
HFD3_k127_6262456_4 Domain of unknown function (DUF3492) K21011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 410.0
HFD3_k127_6262456_5 ERCC4 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 390.0
HFD3_k127_6262456_6 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 344.0
HFD3_k127_6262456_7 Type ii secretion system protein e K02283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 343.0
HFD3_k127_6262456_8 Nucleotidyl transferase K21210 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005731 333.0
HFD3_k127_6262456_9 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 337.0
HFD3_k127_6271576_0 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000001344 201.0
HFD3_k127_6279058_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 416.0
HFD3_k127_6308507_0 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000003923 177.0
HFD3_k127_6335728_0 Acetyl-CoA carboxylase, central region - - - 0.0 1460.0
HFD3_k127_6335728_1 Ketoacyl-synthetase C-terminal extension - - - 7.538e-268 850.0
HFD3_k127_6335728_2 DIM6 NTAB family - - - 0.000009677 57.0
HFD3_k127_6337718_0 Putative carbohydrate binding domain K00702 - 2.4.1.20 0.0 1187.0
HFD3_k127_6337718_1 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0 1149.0
HFD3_k127_6337718_10 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004859 549.0
HFD3_k127_6337718_11 Glycosyl transferase 4-like domain K15521 - 2.4.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005787 526.0
HFD3_k127_6337718_12 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 507.0
HFD3_k127_6337718_13 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005643 525.0
HFD3_k127_6337718_14 Alcohol dehydrogenase groes K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007777 497.0
HFD3_k127_6337718_15 Protein synonym peptidase M K01265 GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564,GO:1901605 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 483.0
HFD3_k127_6337718_16 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000954 489.0
HFD3_k127_6337718_17 Transposase and inactivated derivatives K07486 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 487.0
HFD3_k127_6337718_18 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 484.0
HFD3_k127_6337718_19 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 494.0
HFD3_k127_6337718_2 PFAM Glycoside hydrolase, family 38 K01191 - 3.2.1.24 0.0 1023.0
HFD3_k127_6337718_20 (Pantothenic acid kinase)) K00867 GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 463.0
HFD3_k127_6337718_21 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 445.0
HFD3_k127_6337718_22 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 436.0
HFD3_k127_6337718_23 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004087 434.0
HFD3_k127_6337718_24 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 430.0
HFD3_k127_6337718_25 Delta-aminolevulinic acid dehydratase K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 425.0
HFD3_k127_6337718_26 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 439.0
HFD3_k127_6337718_27 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005175 413.0
HFD3_k127_6337718_28 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 406.0
HFD3_k127_6337718_29 transferase activity, transferring alkyl or aryl (other than methyl) groups K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009411 369.0
HFD3_k127_6337718_3 Methylmalonyl-CoA mutase K14447 - 5.4.99.63 3.839e-311 968.0
HFD3_k127_6337718_30 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 364.0
HFD3_k127_6337718_31 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004527 363.0
HFD3_k127_6337718_32 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008598 392.0
HFD3_k127_6337718_33 PFAM Enoyl-CoA hydratase isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 348.0
HFD3_k127_6337718_34 dna ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005779 346.0
HFD3_k127_6337718_35 transcriptional regulator K01420,K10914,K21561,K21564 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 330.0
HFD3_k127_6337718_36 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007985 332.0
HFD3_k127_6337718_37 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 325.0
HFD3_k127_6337718_38 MATE efflux family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 322.0
HFD3_k127_6337718_39 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 316.0
HFD3_k127_6337718_4 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 2.399e-255 814.0
HFD3_k127_6337718_40 RNA 2'-O ribose methyltransferase substrate binding K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 319.0
HFD3_k127_6337718_41 oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 307.0
HFD3_k127_6337718_42 Pkd domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004443 308.0
HFD3_k127_6337718_43 N-6 DNA Methylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006003 310.0
HFD3_k127_6337718_44 Dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002544 286.0
HFD3_k127_6337718_45 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000003217 267.0
HFD3_k127_6337718_46 hydrolase K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001576 256.0
HFD3_k127_6337718_47 COG2801 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001218 250.0
HFD3_k127_6337718_48 Tyrosine phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001629 256.0
HFD3_k127_6337718_49 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000000000000000000000000003616 246.0
HFD3_k127_6337718_5 DNA segregation ATPase FtsK SpoIIIE and related K03466 - - 6.491e-221 734.0
HFD3_k127_6337718_50 Cation efflux family - - - 0.00000000000000000000000000000000000000000000000000000000000000000004822 239.0
HFD3_k127_6337718_51 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000001999 239.0
HFD3_k127_6337718_52 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000004111 246.0
HFD3_k127_6337718_53 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000269 224.0
HFD3_k127_6337718_54 Integrase, catalytic region - - - 0.000000000000000000000000000000000000000000000000000000000000008868 221.0
HFD3_k127_6337718_55 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000009165 215.0
HFD3_k127_6337718_56 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000004861 212.0
HFD3_k127_6337718_57 Cupin superfamily (DUF985) K09705 - - 0.000000000000000000000000000000000000000000000000000000006556 203.0
HFD3_k127_6337718_58 of HD superfamily K07023 - - 0.000000000000000000000000000000000000000000000000003981 193.0
HFD3_k127_6337718_59 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000003533 183.0
HFD3_k127_6337718_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008822 589.0
HFD3_k127_6337718_60 Protein of unknown function (DUF1203) - - - 0.000000000000000000000000000000000000000000000364 175.0
HFD3_k127_6337718_61 Putative bacterial sensory transduction regulator - - - 0.00000000000000000000000000000000000000000001485 175.0
HFD3_k127_6337718_62 HTH domain - - - 0.0000000000000000000000000000000000000000001877 166.0
HFD3_k127_6337718_63 Metal-dependent hydrolase K07043 - - 0.000000000000000000000000000000000000000001609 162.0
HFD3_k127_6337718_64 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000005881 148.0
HFD3_k127_6337718_65 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000001618 161.0
HFD3_k127_6337718_66 Belongs to the peptidase S51 family K13282 - 3.4.15.6 0.000000000000000000000000000000000006732 147.0
HFD3_k127_6337718_67 GGDEF domain - - - 0.00000000000000000000000000000000000743 151.0
HFD3_k127_6337718_68 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA - - - 0.00000000000000000000000000000000002467 149.0
HFD3_k127_6337718_69 - - - - 0.00000000000000000000000000000000004771 143.0
HFD3_k127_6337718_7 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009697 576.0
HFD3_k127_6337718_71 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000472 135.0
HFD3_k127_6337718_72 Transcriptional regulator K10947 - - 0.000000000000000000000000000000002815 132.0
HFD3_k127_6337718_73 Domain of unknown function (DUF4440) - - - 0.00000000000000000000000000000003631 135.0
HFD3_k127_6337718_74 Nudix hydrolase - - - 0.00000000000000000000000000000007895 130.0
HFD3_k127_6337718_75 Metal-sensitive transcriptional repressor K21600 - - 0.000000000000000000000000000000388 125.0
HFD3_k127_6337718_76 Helix-turn-helix - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000005294 130.0
HFD3_k127_6337718_78 diguanylate cyclase - - - 0.000000000000000000001923 108.0
HFD3_k127_6337718_79 Glycine betaine ABC transporter substrate-binding protein K05845 - - 0.00000000000000002428 93.0
HFD3_k127_6337718_8 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 567.0
HFD3_k127_6337718_80 Mo-molybdopterin cofactor metabolic process K03636,K21142 - 2.8.1.12 0.0000000000000001031 85.0
HFD3_k127_6337718_81 Uroporphyrinogen-III synthase HemD K01719,K13542 - 2.1.1.107,4.2.1.75 0.0000000000000002418 93.0
HFD3_k127_6337718_82 PFAM Heavy metal transport detoxification protein - - - 0.00000000000000336 77.0
HFD3_k127_6337718_84 - - - - 0.000000000000347 79.0
HFD3_k127_6337718_85 Thiamine-binding protein - - - 0.0000000000006234 72.0
HFD3_k127_6337718_86 Hemerythrin HHE cation binding domain - - - 0.00000000001421 71.0
HFD3_k127_6337718_87 - - - - 0.00000000006988 67.0
HFD3_k127_6337718_88 - - - - 0.0000000004722 73.0
HFD3_k127_6337718_89 peptidoglycan-binding domain-containing protein - - - 0.0000000004921 72.0
HFD3_k127_6337718_9 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006626 553.0
HFD3_k127_6337718_90 NlpC/P60 family K19223,K19224,K21471 - - 0.000004835 58.0
HFD3_k127_6337718_91 helix_turn_helix, Lux Regulon - - - 0.00001668 51.0
HFD3_k127_634142_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000826 466.0
HFD3_k127_634142_1 Protein involved in transcription factor activity, ATP binding, drug transporter activity, ATPase activity, metal ion binding, regulation of transcription, DNA-dependent, drug transport, metal ion transport, defense response to pathogen and response to antibiotic K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003497 400.0
HFD3_k127_634142_2 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 353.0
HFD3_k127_634142_3 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000178 261.0
HFD3_k127_634142_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000005062 174.0
HFD3_k127_634142_5 Domain of unknown function (DUF2703) - - - 0.0000000000000000000000000000000000000000000001914 173.0
HFD3_k127_634142_6 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000001521 138.0
HFD3_k127_634142_7 Regulatory protein ArsR K03892 - - 0.000000000000000000000000001082 116.0
HFD3_k127_634142_8 COG1680 Beta-lactamase class C and other penicillin binding K01286 - 3.4.16.4 0.00001646 57.0
HFD3_k127_6352109_0 SMART HNH nuclease - - - 0.00000000000000000000000000000000000000007811 165.0
HFD3_k127_6352109_1 amine dehydrogenase activity - - - 0.0000000002293 72.0
HFD3_k127_6352109_2 N-acetylglucosaminylinositol deacetylase activity - - - 0.0000355 46.0
HFD3_k127_6364842_0 CoA binding domain - - - 5.924e-311 972.0
HFD3_k127_6364842_1 Proteasomal ATPase OB/ID domain K13527 - - 6.553e-302 932.0
HFD3_k127_6364842_10 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003895 607.0
HFD3_k127_6364842_11 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 517.0
HFD3_k127_6364842_12 4Fe-4S dicluster domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007477 500.0
HFD3_k127_6364842_13 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 413.0
HFD3_k127_6364842_14 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 416.0
HFD3_k127_6364842_15 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 - 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 379.0
HFD3_k127_6364842_16 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003845 379.0
HFD3_k127_6364842_17 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 377.0
HFD3_k127_6364842_18 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 - 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 329.0
HFD3_k127_6364842_19 FAD binding domain K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 325.0
HFD3_k127_6364842_2 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 7.506e-280 873.0
HFD3_k127_6364842_20 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 341.0
HFD3_k127_6364842_21 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 318.0
HFD3_k127_6364842_22 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 301.0
HFD3_k127_6364842_23 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004995 296.0
HFD3_k127_6364842_24 allophanate hydrolase subunit 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000437 292.0
HFD3_k127_6364842_25 transcriptional regulator K09017 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001685 285.0
HFD3_k127_6364842_26 Belongs to the FPG family K05522 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008769 279.0
HFD3_k127_6364842_27 Belongs to the UPF0271 (lamB) family K07160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001495 278.0
HFD3_k127_6364842_28 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000005532 270.0
HFD3_k127_6364842_29 homoserine kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001014 270.0
HFD3_k127_6364842_3 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K13571 - 6.3.1.19 4.723e-273 851.0
HFD3_k127_6364842_30 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001433 260.0
HFD3_k127_6364842_31 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000022 248.0
HFD3_k127_6364842_32 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007415 243.0
HFD3_k127_6364842_33 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000004493 232.0
HFD3_k127_6364842_34 NUDIX hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000946 229.0
HFD3_k127_6364842_36 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000001495 219.0
HFD3_k127_6364842_37 response regulator, receiver K02483,K07667 - - 0.0000000000000000000000000000000000000000000000000000001152 198.0
HFD3_k127_6364842_38 Peptidase S16, lon domain protein K01338,K07157 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000004421 196.0
HFD3_k127_6364842_39 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000000213 185.0
HFD3_k127_6364842_4 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 7.083e-266 830.0
HFD3_k127_6364842_40 endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000005987 177.0
HFD3_k127_6364842_41 nUDIX hydrolase K08311 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010468,GO:0010604,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019219,GO:0019222,GO:0019439,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0033554,GO:0034353,GO:0034641,GO:0034655,GO:0043167,GO:0043169,GO:0043170,GO:0043487,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0045935,GO:0046483,GO:0046700,GO:0046872,GO:0048518,GO:0048519,GO:0048522,GO:0050779,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000000000000000000000000000001786 172.0
HFD3_k127_6364842_42 Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.0000000000000000000000000000000000000000000296 175.0
HFD3_k127_6364842_43 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.00000000000000000000000000000000000000001055 154.0
HFD3_k127_6364842_46 lipid kinase activity - - - 0.00000000000000000000000000000000002931 144.0
HFD3_k127_6364842_48 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.000000000000000000000000000002337 130.0
HFD3_k127_6364842_49 - - - - 0.0000000000000000000000000001091 121.0
HFD3_k127_6364842_5 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 2.205e-265 826.0
HFD3_k127_6364842_50 Helix-turn-helix domain, rpiR family - - - 0.0000000000000000000000000001267 126.0
HFD3_k127_6364842_51 protein secretion K03116,K03117 GO:0003674,GO:0005215 - 0.00000000000000000000000742 106.0
HFD3_k127_6364842_52 Acetyltransferase (GNAT) family - - - 0.0000000000000000000001801 107.0
HFD3_k127_6364842_53 Glyoxalase-like domain - - - 0.000000000000000000007998 93.0
HFD3_k127_6364842_54 - - - - 0.00000000000000000001125 101.0
HFD3_k127_6364842_55 Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation K13570 - - 0.00000000000000000004538 91.0
HFD3_k127_6364842_56 Psort location Cytoplasmic, score - - - 0.0000000000000000001398 100.0
HFD3_k127_6364842_58 - - - - 0.000000000000000001529 89.0
HFD3_k127_6364842_6 Pup-ligase protein K20814 - 3.5.1.119 1.423e-242 756.0
HFD3_k127_6364842_7 DSHCT K03727 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 1.308e-236 761.0
HFD3_k127_6364842_8 MgsA AAA+ ATPase C terminal K07478 - - 2.577e-210 661.0
HFD3_k127_6364842_9 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 5.451e-202 640.0
HFD3_k127_6375325_0 Pyridoxal-dependent decarboxylase conserved domain K01634 - 4.1.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 327.0
HFD3_k127_6375325_1 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 324.0
HFD3_k127_6375325_2 peptidase activity K01286 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000004522 228.0
HFD3_k127_6375325_3 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000005879 177.0
HFD3_k127_6375325_4 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000004865 187.0
HFD3_k127_6375325_5 thiolester hydrolase activity K17362 - - 0.0000000000000000000000000000002381 132.0
HFD3_k127_6382432_0 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 - 2.3.3.9 8.476e-285 887.0
HFD3_k127_6382432_1 Electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008603 271.0
HFD3_k127_6382432_2 PFAM Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000002149 173.0
HFD3_k127_6382432_3 Rhodanese Homology Domain - - - 0.00001095 58.0
HFD3_k127_6391976_0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 343.0
HFD3_k127_6391976_1 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 327.0
HFD3_k127_6391976_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000001168 211.0
HFD3_k127_6391976_3 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000000000000000000000000004696 119.0
HFD3_k127_6391976_4 Ribosomal protein L33 K02913 - - 0.0000000000000000000004137 98.0
HFD3_k127_6391976_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000304 81.0
HFD3_k127_6421250_0 Belongs to the cysteine synthase cystathionine beta- synthase family - - - 1.699e-256 801.0
HFD3_k127_6421250_1 PFAM magnesium chelatase ChlI subunit K07391 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000992 582.0
HFD3_k127_6421250_10 heme binding K08259,K21472 - 3.4.24.75 0.0000000000000000000000000000000002816 139.0
HFD3_k127_6421250_11 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000139 53.0
HFD3_k127_6421250_2 Ribosomal protein S2 K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009138 409.0
HFD3_k127_6421250_3 Pyridoxal-phosphate dependent enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007597 402.0
HFD3_k127_6421250_4 Phage integrase, N-terminal SAM-like domain K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007233 389.0
HFD3_k127_6421250_5 Sigma-70 region 3 K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 359.0
HFD3_k127_6421250_6 helicase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 329.0
HFD3_k127_6421250_7 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000481 317.0
HFD3_k127_6421250_8 DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 329.0
HFD3_k127_6421250_9 PFAM Helix-turn-helix, type 11 domain protein - - - 0.0000000000000000000000000000000000000000000000007467 182.0
HFD3_k127_6428027_0 Peptidase inhibitor I9 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000109 294.0
HFD3_k127_6428027_1 CHRD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006166 252.0
HFD3_k127_6428027_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008467 245.0
HFD3_k127_6428027_3 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001958 239.0
HFD3_k127_6428027_4 Lysyl oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000004455 225.0
HFD3_k127_6428027_5 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000004666 218.0
HFD3_k127_6428027_6 Domain of unknown function (DUF427) - - - 0.00000000000000000000000000000000000000000000000000000000004309 211.0
HFD3_k127_6428027_7 Cupin - - - 0.0000000000000000000000000000000000000001354 156.0
HFD3_k127_6428027_9 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006355,GO:0006401,GO:0006402,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0017148,GO:0019219,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045892,GO:0045926,GO:0045927,GO:0045934,GO:0046483,GO:0046700,GO:0048518,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000001068 74.0
HFD3_k127_6454083_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 1.052e-315 1002.0
HFD3_k127_6454083_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 2.033e-218 691.0
HFD3_k127_6454083_10 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000668 263.0
HFD3_k127_6454083_11 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000005574 246.0
HFD3_k127_6454083_12 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000001402 221.0
HFD3_k127_6454083_13 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000001215 196.0
HFD3_k127_6454083_14 Aldo/keto reductase family K18471 - - 0.00000000000000000000000000000000000000000000000003793 190.0
HFD3_k127_6454083_15 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000007138 190.0
HFD3_k127_6454083_16 Transcriptional regulator - - - 0.000000000000000000000000000000000000000007237 161.0
HFD3_k127_6454083_17 helix_turn_helix ASNC type - - - 0.000000000000000000000000000000000000000009557 171.0
HFD3_k127_6454083_18 2-phosphosulpholactate phosphatase K05979 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 0.00000000000000000000000000226 121.0
HFD3_k127_6454083_19 cell cycle K05589,K13052 - - 0.000000000000000000000001774 109.0
HFD3_k127_6454083_2 Aminotransferase class-III K01845 - 5.4.3.8 4.495e-204 644.0
HFD3_k127_6454083_20 sulfate ABC transporter K02048 - - 0.000000000000000000000005684 105.0
HFD3_k127_6454083_21 endonuclease activity - - - 0.000003965 49.0
HFD3_k127_6454083_3 MazG nucleotide pyrophosphohydrolase domain K02499 - - 5.333e-199 632.0
HFD3_k127_6454083_4 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 532.0
HFD3_k127_6454083_5 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 524.0
HFD3_k127_6454083_6 Domain of unknown function (DUF4032) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 492.0
HFD3_k127_6454083_7 Domain of unknown function (DUF4162) K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 453.0
HFD3_k127_6454083_8 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005186 331.0
HFD3_k127_6454083_9 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009576 313.0
HFD3_k127_6481460_0 UDP binding domain K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 548.0
HFD3_k127_6481460_1 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784,K12448 - 5.1.3.2,5.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004837 419.0
HFD3_k127_6481460_2 3-beta hydroxysteroid dehydrogenase/isomerase family K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 386.0
HFD3_k127_6481460_3 thiolester hydrolase activity K01990,K06889 GO:0008150,GO:0009987,GO:0051301 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 352.0
HFD3_k127_6481460_4 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000008431 242.0
HFD3_k127_6481460_5 MDMPI C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000009192 206.0
HFD3_k127_6481460_6 - - - - 0.0000000000000000000000000000000000000000000000000001042 189.0
HFD3_k127_6481460_7 Pro-kumamolisin, activation domain - - - 0.000000006149 61.0
HFD3_k127_6481962_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1157.0
HFD3_k127_6481962_1 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 563.0
HFD3_k127_6481962_2 GMC oxidoreductase K00108 - 1.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 411.0
HFD3_k127_6481962_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000156 248.0
HFD3_k127_6481962_4 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000001359 219.0
HFD3_k127_6481962_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000001917 196.0
HFD3_k127_6481962_6 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000003911 167.0
HFD3_k127_6481962_7 F420H(2)-dependent quinone reductase - - - 0.00000000000000000000000000000000000002424 148.0
HFD3_k127_6481962_8 Uncharacterized conserved protein (DUF2277) - - - 0.0000000000000000000000000000003826 124.0
HFD3_k127_6481962_9 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000006369 82.0
HFD3_k127_6542972_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.0 1068.0
HFD3_k127_6542972_1 protein synonym multiple resistance and pH homeostasis protein A K00341,K05565 - 1.6.5.3 6.066e-242 767.0
HFD3_k127_6542972_10 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 483.0
HFD3_k127_6542972_11 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 449.0
HFD3_k127_6542972_12 acr, cog1565 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 362.0
HFD3_k127_6542972_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 317.0
HFD3_k127_6542972_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007856 301.0
HFD3_k127_6542972_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000288 283.0
HFD3_k127_6542972_16 Protein of unknown function (DUF520) K09767 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001122 244.0
HFD3_k127_6542972_17 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.0000000000000000000000000000000000000000000000000000000355 203.0
HFD3_k127_6542972_18 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000001343 188.0
HFD3_k127_6542972_19 Belongs to the complex I subunit 6 family K00339,K05578 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000002127 198.0
HFD3_k127_6542972_2 Protein synonym NADH dehydrogenase I subunit M K00342 - 1.6.5.3 5.505e-240 764.0
HFD3_k127_6542972_20 peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000000009887 193.0
HFD3_k127_6542972_21 peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000000002098 176.0
HFD3_k127_6542972_22 Choline/ethanolamine kinase - - - 0.000000000000000000000000000000000000000000001256 184.0
HFD3_k127_6542972_23 pyridoxamine 5-phosphate - - - 0.0000000000000000000000000000000000000000005677 162.0
HFD3_k127_6542972_24 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000000000000000001325 151.0
HFD3_k127_6542972_25 glutamine amidotransferase - - - 0.00000000000000000000000000000000000003798 156.0
HFD3_k127_6542972_26 Protein of unknown function (DUF559) - - - 0.00000000000000000007847 102.0
HFD3_k127_6542972_27 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000005805 81.0
HFD3_k127_6542972_28 HYR domain - - - 0.0000000002151 73.0
HFD3_k127_6542972_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 3.225e-232 721.0
HFD3_k127_6542972_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 5.942e-209 660.0
HFD3_k127_6542972_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 589.0
HFD3_k127_6542972_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 544.0
HFD3_k127_6542972_7 ATPases associated with a variety of cellular activities K15738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005672 542.0
HFD3_k127_6542972_8 protein synonym multiple resistance and pH homeostasis protein A K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 499.0
HFD3_k127_6542972_9 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009537 500.0
HFD3_k127_6549739_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0 1050.0
HFD3_k127_6549739_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 5.05e-321 990.0
HFD3_k127_6549739_10 PFAM LmbE family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 354.0
HFD3_k127_6549739_11 Zc3h12a-like Ribonuclease NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 343.0
HFD3_k127_6549739_12 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003304 338.0
HFD3_k127_6549739_13 Protein of unknown function (DUF455) K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005072 323.0
HFD3_k127_6549739_14 Bacterial PH domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 293.0
HFD3_k127_6549739_15 exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007807 291.0
HFD3_k127_6549739_16 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001742 289.0
HFD3_k127_6549739_17 F420-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002785 284.0
HFD3_k127_6549739_18 Belongs to the GHMP kinase family K00849 - 2.7.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000001566 277.0
HFD3_k127_6549739_19 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000002292 269.0
HFD3_k127_6549739_2 Dak1_2 K07030 - - 6.978e-222 700.0
HFD3_k127_6549739_20 HAD-superfamily hydrolase subfamily IA, variant 3 K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003678 280.0
HFD3_k127_6549739_21 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004204 261.0
HFD3_k127_6549739_22 Cell envelope-related transcriptional attenuator domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003121 255.0
HFD3_k127_6549739_23 Domain of unknown function (DUF222) - - - 0.00000000000000000000000000000000000000000000000000000000000001463 221.0
HFD3_k127_6549739_24 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000000000003078 201.0
HFD3_k127_6549739_25 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000002086 189.0
HFD3_k127_6549739_26 Phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000000000003213 173.0
HFD3_k127_6549739_27 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000000000003065 142.0
HFD3_k127_6549739_28 - - - - 0.0000000000000000000000000000000000005003 154.0
HFD3_k127_6549739_29 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000000000000000006803 145.0
HFD3_k127_6549739_3 Hydrolase CocE NonD family K06978 - - 6.268e-211 674.0
HFD3_k127_6549739_31 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.00000000000000000000000000000000004244 137.0
HFD3_k127_6549739_32 - - - - 0.0000000000000000000000000000142 121.0
HFD3_k127_6549739_33 Ribosomal L28 family K02902 - - 0.0000000000000000000000000001088 117.0
HFD3_k127_6549739_34 Cold shock K03704 - - 0.0000000000000000000000001047 107.0
HFD3_k127_6549739_35 Acyl-CoA dehydrogenase, C-terminal domain K22219 - 1.14.14.21 0.0000000000000000000000009953 118.0
HFD3_k127_6549739_36 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.00000000000000000000009594 99.0
HFD3_k127_6549739_37 endonuclease activity - - - 0.000000000000000144 89.0
HFD3_k127_6549739_4 CoA-transferase family III K01796 - 5.1.99.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007301 584.0
HFD3_k127_6549739_5 Acetylornithine deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 519.0
HFD3_k127_6549739_6 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 471.0
HFD3_k127_6549739_7 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 452.0
HFD3_k127_6549739_8 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 447.0
HFD3_k127_6549739_9 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 382.0
HFD3_k127_6577540_0 ABC1 family K03688 - - 2.613e-198 641.0
HFD3_k127_6577540_1 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 509.0
HFD3_k127_6577540_2 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 432.0
HFD3_k127_6577540_3 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000243 173.0
HFD3_k127_6577540_4 MMPL family K06994,K07003 - - 0.00000000000000008308 82.0
HFD3_k127_6577540_5 Drug exporters of the RND superfamily K06994 - - 0.00008862 53.0
HFD3_k127_6578257_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2084.0
HFD3_k127_6578257_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2043.0
HFD3_k127_6578257_2 Glycosyl hydrolase family 1 K05350 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 601.0
HFD3_k127_6578257_3 helix_turn _helix lactose operon repressor K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004155 339.0
HFD3_k127_6578257_4 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000000000004965 213.0
HFD3_k127_6578257_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000004072 158.0
HFD3_k127_6578257_6 Acetyltransferase (GNAT) domain - - - 0.000000000000009294 85.0
HFD3_k127_6685916_0 Filamentation induced by cAMP protein fic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 484.0
HFD3_k127_6685916_1 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 321.0
HFD3_k127_6685916_2 Rifampin ADP-ribosyl transferase K19062 - - 0.000000000000000000000000000000000000000000000000005025 184.0
HFD3_k127_6685916_3 Protein of unknown function DUF262 - - - 0.00000000000000000000000001524 110.0
HFD3_k127_6685916_4 PFAM WD40 domain protein beta Propeller - - - 0.00001324 50.0
HFD3_k127_6721989_0 ATPases associated with a variety of cellular activities K01990,K09691 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009586 499.0
HFD3_k127_6721989_1 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000949 160.0
HFD3_k127_6721989_2 Transport permease protein K01992,K09690 - - 0.0000000000000000000001684 109.0
HFD3_k127_6780407_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 5.956e-274 850.0
HFD3_k127_6780407_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 3.032e-251 783.0
HFD3_k127_6780407_10 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000261 212.0
HFD3_k127_6780407_11 - - - - 0.0000000000000000000000000000000000000000000000000000000008646 208.0
HFD3_k127_6780407_12 nUDIX hydrolase - GO:0003674,GO:0003824,GO:0016787,GO:0016817,GO:0016818 - 0.0000000000000000000000000000000000000000000000004471 184.0
HFD3_k127_6780407_13 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000001648 183.0
HFD3_k127_6780407_14 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000003251 149.0
HFD3_k127_6780407_16 Prokaryotic phospholipase A2 - - - 0.000000000000000006918 89.0
HFD3_k127_6780407_17 Psort location Cytoplasmic, score - - - 0.00000000001218 75.0
HFD3_k127_6780407_2 synthetase K18688 - 6.2.1.42 1.808e-233 735.0
HFD3_k127_6780407_3 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 7.584e-214 677.0
HFD3_k127_6780407_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 450.0
HFD3_k127_6780407_5 Pirin K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 446.0
HFD3_k127_6780407_6 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007922 437.0
HFD3_k127_6780407_7 helix_turn_helix isocitrate lyase regulation K02624 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001634 283.0
HFD3_k127_6780407_8 NlpC/P60 family K21471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000545 281.0
HFD3_k127_6780407_9 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004885 270.0
HFD3_k127_6781899_0 PFAM ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 319.0
HFD3_k127_6781899_1 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007243 309.0
HFD3_k127_6781899_2 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006377 270.0
HFD3_k127_6781899_3 His Kinase A (phosphoacceptor) domain K07642 - 2.7.13.3 0.0000000000000000000000000000009437 125.0
HFD3_k127_6809799_0 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001611 284.0
HFD3_k127_6809799_1 ABC transporter transmembrane region K11085 - - 0.0000000000000000000000000000000000001395 143.0
HFD3_k127_6839052_0 FtsX-like permease family - - - 0.0000000000002789 84.0
HFD3_k127_6988144_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 5.921e-223 709.0
HFD3_k127_6988144_1 Belongs to the RtcB family K14415 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.5.1.3 3.695e-207 655.0
HFD3_k127_6988144_10 Peptidase M1, membrane alanine aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 484.0
HFD3_k127_6988144_11 Capsule synthesis protein K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 476.0
HFD3_k127_6988144_12 L-lysine 6-monooxygenase (NADPH-requiring) K07222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 451.0
HFD3_k127_6988144_13 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 431.0
HFD3_k127_6988144_14 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004118 396.0
HFD3_k127_6988144_15 alkaline phosphatase K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 411.0
HFD3_k127_6988144_16 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 388.0
HFD3_k127_6988144_17 alkaline phosphatase K01077,K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007493 382.0
HFD3_k127_6988144_18 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 364.0
HFD3_k127_6988144_19 e3 binding domain K00627,K00658 - 2.3.1.12,2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 356.0
HFD3_k127_6988144_2 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 628.0
HFD3_k127_6988144_20 OsmC-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 303.0
HFD3_k127_6988144_21 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 327.0
HFD3_k127_6988144_22 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 313.0
HFD3_k127_6988144_23 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 294.0
HFD3_k127_6988144_24 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001288 246.0
HFD3_k127_6988144_25 Short-chain dehydrogenase reductase (SDR) - - - 0.0000000000000000000000000000000000000000000000000000000000000000143 233.0
HFD3_k127_6988144_26 ABC transporter K15555 - - 0.0000000000000000000000000000000000000000000000000000000000000001353 229.0
HFD3_k127_6988144_27 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000008141 217.0
HFD3_k127_6988144_28 Fungal family of unknown function (DUF1776) - - - 0.0000000000000000000000000000000000000000000000000000002779 214.0
HFD3_k127_6988144_29 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000009391 214.0
HFD3_k127_6988144_3 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005276 580.0
HFD3_k127_6988144_30 Belongs to the peptidase S1B family K01173 - - 0.0000000000000000000000000000000000000000000000003006 193.0
HFD3_k127_6988144_31 Belongs to the globin family - - - 0.0000000000000000000000000000000002159 143.0
HFD3_k127_6988144_32 Transcriptional regulator - - - 0.0000000000000000000000000000000002434 154.0
HFD3_k127_6988144_33 Belongs to the small heat shock protein (HSP20) family K13993 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016310,GO:0019538,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0036294,GO:0040007,GO:0040008,GO:0042221,GO:0042594,GO:0043170,GO:0043207,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045926,GO:0046777,GO:0048519,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071496,GO:0071704,GO:0071944,GO:0075136,GO:1901564 - 0.00000000000000000000000001474 113.0
HFD3_k127_6988144_34 - - - - 0.00000000000000000000005619 108.0
HFD3_k127_6988144_35 Belongs to the globin family - - - 0.0000000000000000000000958 111.0
HFD3_k127_6988144_36 - - - - 0.00000000000000000000009675 106.0
HFD3_k127_6988144_37 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000004617 100.0
HFD3_k127_6988144_38 - - - - 0.0000000000000000000005831 104.0
HFD3_k127_6988144_39 Archease protein family (MTH1598/TM1083) - - - 0.00000000000000000003784 95.0
HFD3_k127_6988144_4 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004821 569.0
HFD3_k127_6988144_42 Trypsin-like peptidase domain K01173 - - 0.0000000000001212 85.0
HFD3_k127_6988144_43 Predicted membrane protein (DUF2157) - - - 0.000000000005909 80.0
HFD3_k127_6988144_44 Phosphopantetheine attachment site - - - 0.000000004354 64.0
HFD3_k127_6988144_5 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 559.0
HFD3_k127_6988144_6 trisaccharide binding K03556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 567.0
HFD3_k127_6988144_7 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 501.0
HFD3_k127_6988144_8 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002529 507.0
HFD3_k127_6988144_9 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 488.0
HFD3_k127_7003983_0 Acyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 543.0
HFD3_k127_7015542_0 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005478 400.0
HFD3_k127_7015542_1 Glycosyl transferase 4-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008398 278.0
HFD3_k127_7015542_2 Predicted membrane protein (DUF2142) - - - 0.0000000000000000000000000000000005293 149.0
HFD3_k127_7028367_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 7.629e-290 896.0
HFD3_k127_7028367_1 PFAM deoxyribose-phosphate aldolase phospho-2- dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005878 537.0
HFD3_k127_7028367_10 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000000006128 191.0
HFD3_k127_7028367_11 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000009712 192.0
HFD3_k127_7028367_12 COG NOG14600 non supervised orthologous group - - - 0.00000000000000000000000000000000000000000000001157 172.0
HFD3_k127_7028367_13 AI-2E family transporter - - - 0.00000000000000000000000000000000000004102 164.0
HFD3_k127_7028367_14 Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000000000000000000000005849 142.0
HFD3_k127_7028367_16 - - - - 0.00000000000000007891 80.0
HFD3_k127_7028367_17 - - - - 0.000000000000007674 85.0
HFD3_k127_7028367_19 Single-stranded DNA-binding protein K03111 - - 0.000001099 55.0
HFD3_k127_7028367_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008286 541.0
HFD3_k127_7028367_3 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 452.0
HFD3_k127_7028367_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 334.0
HFD3_k127_7028367_5 Phage integrase, N-terminal SAM-like domain K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006861 310.0
HFD3_k127_7028367_6 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003539 284.0
HFD3_k127_7028367_7 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000878 249.0
HFD3_k127_7028367_8 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000006771 211.0
HFD3_k127_7028367_9 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000005883 202.0
HFD3_k127_7037477_0 TatD related DNase K03424 - - 0.0000000000000006139 87.0
HFD3_k127_7084218_0 AMP-binding enzyme C-terminal domain K00666 - - 3.188e-249 779.0
HFD3_k127_7084218_1 helicase K03722 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.4.12 3.631e-247 778.0
HFD3_k127_7084218_10 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 377.0
HFD3_k127_7084218_11 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 - 2.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 366.0
HFD3_k127_7084218_12 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 368.0
HFD3_k127_7084218_13 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 349.0
HFD3_k127_7084218_14 Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000417 342.0
HFD3_k127_7084218_15 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 334.0
HFD3_k127_7084218_16 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 303.0
HFD3_k127_7084218_17 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 288.0
HFD3_k127_7084218_18 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000347 240.0
HFD3_k127_7084218_19 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000004633 223.0
HFD3_k127_7084218_2 Carboxyl transferase domain - - - 4.054e-244 779.0
HFD3_k127_7084218_20 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000005428 173.0
HFD3_k127_7084218_21 transferase activity, transferring alkyl or aryl (other than methyl) groups K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.000000000000000000000000000000000006871 149.0
HFD3_k127_7084218_22 PFAM regulatory protein, MarR - - - 0.000000000000000000003298 99.0
HFD3_k127_7084218_23 Evidence 4 Homologs of previously reported genes of - - - 0.00000006797 63.0
HFD3_k127_7084218_3 Catalyzes the attachment of glycine to tRNA(Gly) K01880 - 6.1.1.14 2.076e-240 747.0
HFD3_k127_7084218_4 PFAM AMP-dependent synthetase and ligase K00666 - - 7.459e-225 709.0
HFD3_k127_7084218_5 Acyclic terpene utilisation family protein AtuA - - - 5.457e-207 661.0
HFD3_k127_7084218_6 Acetyl propionyl-CoA carboxylase, alpha subunit K01959,K01965,K01968 - 6.4.1.1,6.4.1.3,6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006631 586.0
HFD3_k127_7084218_7 chorismate binding enzyme K02552 - 5.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 514.0
HFD3_k127_7084218_8 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 439.0
HFD3_k127_7084218_9 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 413.0
HFD3_k127_7088481_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 7.052e-294 905.0
HFD3_k127_7088481_1 L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007424 560.0
HFD3_k127_7088481_10 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000006552 194.0
HFD3_k127_7088481_11 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.00000000000000000000000000000000000000000000000003962 183.0
HFD3_k127_7088481_12 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.00000000000000000000000000000000000000000000000005371 180.0
HFD3_k127_7088481_13 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000003934 177.0
HFD3_k127_7088481_14 - - - - 0.000000000000000000000000000000000000000000369 162.0
HFD3_k127_7088481_15 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000004474 165.0
HFD3_k127_7088481_16 Acetyltransferase (GNAT) domain K06977 - - 0.000000000000000000000000000000000000001524 152.0
HFD3_k127_7088481_17 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000619 134.0
HFD3_k127_7088481_18 lactoylglutathione lyase activity - - - 0.000000000000000000000000006782 114.0
HFD3_k127_7088481_19 Nucleoside 2-deoxyribosyltransferase like K08728 - 2.4.2.6 0.0000000000000000000007096 100.0
HFD3_k127_7088481_2 Aminotransferase K00812,K14267 - 2.6.1.1,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005308 513.0
HFD3_k127_7088481_21 Ribbon-helix-helix protein, copG family - - - 0.0000000001046 63.0
HFD3_k127_7088481_22 Cupredoxin-like domain - - - 0.000003613 56.0
HFD3_k127_7088481_3 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 450.0
HFD3_k127_7088481_4 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 451.0
HFD3_k127_7088481_5 Calcineurin-like phosphoesterase K03651 - 3.1.4.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 424.0
HFD3_k127_7088481_6 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009003 340.0
HFD3_k127_7088481_7 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 320.0
HFD3_k127_7088481_8 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009265 318.0
HFD3_k127_7088481_9 flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001189 245.0
HFD3_k127_7090889_0 Aminotransferase class-V - - - 9.774e-277 861.0
HFD3_k127_7090889_1 dienelactone hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000559 258.0
HFD3_k127_7090889_10 InterPro IPR014922 - - - 0.00000000000000000001521 96.0
HFD3_k127_7090889_2 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000567 215.0
HFD3_k127_7090889_3 pyridoxamine 5-phosphate - - - 0.0000000000000000000000000000000000000000000000000000000001372 214.0
HFD3_k127_7090889_4 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000001435 175.0
HFD3_k127_7090889_5 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000005263 162.0
HFD3_k127_7090889_6 Protein of unknown function (DUF1211) - - - 0.00000000000000000000000000000000000000001587 160.0
HFD3_k127_7090889_7 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K22185 - 1.1.1.175 0.000000000000000000000000000000000003345 139.0
HFD3_k127_7090889_8 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 - 2.3.3.9 0.000000000000000000000000000000007727 132.0
HFD3_k127_7090889_9 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.0000000000000000000000001386 114.0
HFD3_k127_7091608_0 - - - - 0.00000000000000000000000000000000000008229 149.0
HFD3_k127_7094727_0 Salmonella virulence plasmid 65kDa B protein - - - 1.773e-300 992.0
HFD3_k127_7094727_1 TAP-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001315 272.0
HFD3_k127_7094727_2 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006401 246.0
HFD3_k127_7094727_3 Acid phosphatase homologues K06153,K19302 - 3.6.1.27 0.000000000000000000000000000000000000000001337 163.0
HFD3_k127_7094727_4 Histidine kinase - - - 0.000000000000000000000007347 108.0
HFD3_k127_7094727_5 membrane protein (DUF2078) K08982 - - 0.00001138 54.0
HFD3_k127_7095338_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 2.954e-297 937.0
HFD3_k127_7095338_1 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 1.091e-289 897.0
HFD3_k127_7095338_10 - - - - 0.00000000000000000000000000000000000000000000000000002245 191.0
HFD3_k127_7095338_11 T4-like virus tail tube protein gp19 - - - 0.000000000000000000000000000000000000000000000000001299 186.0
HFD3_k127_7095338_12 Gene 25-like lysozyme K06903 - - 0.000000000000000000000000000000000000000000000000003656 184.0
HFD3_k127_7095338_14 PFAM Peptidoglycan-binding - - - 0.000000000000000000000000000000000000006738 153.0
HFD3_k127_7095338_15 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.000000000000000000000000000000000000009597 147.0
HFD3_k127_7095338_16 Putative peptidoglycan binding domain - - - 0.000000000000000000000000000000000002929 144.0
HFD3_k127_7095338_17 phage tail protein - - - 0.000000000000000000000000000000001271 137.0
HFD3_k127_7095338_18 Domain of unknown function (DUF4157) - - - 0.0000000000000000000000001139 124.0
HFD3_k127_7095338_19 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000004549 119.0
HFD3_k127_7095338_2 Phage tail sheath C-terminal domain K06907 - - 8.696e-243 762.0
HFD3_k127_7095338_20 Protein of unknown function (DUF4255) - - - 0.0000000000000000000001963 106.0
HFD3_k127_7095338_21 WD40-like Beta Propeller Repeat - - - 0.0000000000000000005787 102.0
HFD3_k127_7095338_22 - - - - 0.0000000001217 63.0
HFD3_k127_7095338_23 Zinc finger domain - - - 0.00000005442 63.0
HFD3_k127_7095338_24 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.000284 51.0
HFD3_k127_7095338_3 Baseplate J-like protein - - - 7.428e-242 763.0
HFD3_k127_7095338_4 PFAM phenylalanine histidine ammonia-lyase K01745 - 4.3.1.3 2.646e-206 658.0
HFD3_k127_7095338_5 Phage late control gene D protein (GPD) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 566.0
HFD3_k127_7095338_6 cell adhesion involved in biofilm formation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006723 260.0
HFD3_k127_7095338_7 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000477 231.0
HFD3_k127_7095338_8 Phage tail protein (Tail_P2_I) - - - 0.000000000000000000000000000000000000000000000000000000000000001314 225.0
HFD3_k127_7095338_9 Glycosylase K05522 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000007211 204.0
HFD3_k127_7104249_0 Glycosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 512.0
HFD3_k127_7104249_1 PFAM short chain dehydrogenase K16652 - 1.1.1.333 0.00000000000000000000000000002751 118.0
HFD3_k127_7104249_2 - - - - 0.0000000004745 62.0
HFD3_k127_7134686_0 Acetyltransferases including N-acetylases of ribosomal proteins - - - 0.00000000000000000000000000000000000000000000000000000000000001029 220.0
HFD3_k127_7134686_1 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000005276 125.0
HFD3_k127_7134686_2 FtsX-like permease family - - - 0.0000000000001148 84.0
HFD3_k127_7134686_4 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000951 68.0
HFD3_k127_7134686_5 membrane protein (DUF2078) - - - 0.0000000005644 66.0
HFD3_k127_7134686_6 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.0000004715 59.0
HFD3_k127_7134686_7 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000005539 52.0
HFD3_k127_7134686_8 membrane protein (DUF2078) K08982 - - 0.000004012 53.0
HFD3_k127_7142321_0 Flavin containing amine oxidoreductase - - - 2.07e-255 797.0
HFD3_k127_7142321_1 Belongs to the carbamoyltransferase HypF family K04656 - - 8.943e-227 726.0
HFD3_k127_7142321_10 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0008652,GO:0008743,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030145,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046870,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 1.1.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007119 480.0
HFD3_k127_7142321_11 Glycine cleavage T-protein C-terminal barrel domain K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 457.0
HFD3_k127_7142321_12 PhoD-like phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 463.0
HFD3_k127_7142321_13 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 447.0
HFD3_k127_7142321_14 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 444.0
HFD3_k127_7142321_15 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 436.0
HFD3_k127_7142321_16 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 430.0
HFD3_k127_7142321_17 ribosomal rna small subunit methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 424.0
HFD3_k127_7142321_18 PFAM Bacterial domain of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006201 440.0
HFD3_k127_7142321_19 ABC transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000499 426.0
HFD3_k127_7142321_2 MacB-like periplasmic core domain K02004 - - 1.238e-222 719.0
HFD3_k127_7142321_20 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 425.0
HFD3_k127_7142321_21 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 397.0
HFD3_k127_7142321_22 Dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000369 380.0
HFD3_k127_7142321_23 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 363.0
HFD3_k127_7142321_24 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009193 370.0
HFD3_k127_7142321_25 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 335.0
HFD3_k127_7142321_26 Pyridoxal phosphate biosynthetic protein PdxA K22024 - 1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 336.0
HFD3_k127_7142321_27 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 306.0
HFD3_k127_7142321_28 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 289.0
HFD3_k127_7142321_29 Bacterial transglutaminase-like N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004739 278.0
HFD3_k127_7142321_3 hydrogenase expression formation protein HypD K04654 - - 1.251e-209 656.0
HFD3_k127_7142321_30 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000000000000000000000000000000000000000000000006781 254.0
HFD3_k127_7142321_31 Belongs to the MIP aquaporin (TC 1.A.8) family K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000006893 263.0
HFD3_k127_7142321_32 HupF/HypC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000003606 246.0
HFD3_k127_7142321_33 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000005563 241.0
HFD3_k127_7142321_34 A predicted alpha-helical domain with a conserved ER motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000001065 249.0
HFD3_k127_7142321_35 phosphoheptose isomerase K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000007038 225.0
HFD3_k127_7142321_36 Protein of unknown function (DUF971) K00471 - 1.14.11.1 0.00000000000000000000000000000000000000000000000000000000000009853 227.0
HFD3_k127_7142321_37 PFAM band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000006912 220.0
HFD3_k127_7142321_38 Diacylglycerol kinase K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000002754 218.0
HFD3_k127_7142321_39 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000002272 214.0
HFD3_k127_7142321_4 Circularly permuted ATP-grasp type 2 - - - 4.678e-194 619.0
HFD3_k127_7142321_40 YbaK prolyl-tRNA synthetase associated region - - - 0.00000000000000000000000000000000000000000000000000000001263 201.0
HFD3_k127_7142321_41 Low molecular weight phosphatase family K03741,K18701 - 1.20.4.1,2.8.4.2 0.0000000000000000000000000000000000000000000000000002229 196.0
HFD3_k127_7142321_42 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03325,K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000003849 188.0
HFD3_k127_7142321_43 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000005975 187.0
HFD3_k127_7142321_44 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000001431 179.0
HFD3_k127_7142321_45 glyoxalase bleomycin resistance protein dioxygenase - GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0050896 - 0.00000000000000000000000000000000000000000003275 166.0
HFD3_k127_7142321_46 Domain of Unknown Function (DUF1206) - - - 0.00000000000000000000000000000000000000000003565 172.0
HFD3_k127_7142321_47 Methyltransferase domain - - - 0.00000000000000000000000000000000000001128 153.0
HFD3_k127_7142321_48 Protein of unknown function (DUF664) - - - 0.00000000000000000000000000000000000006023 147.0
HFD3_k127_7142321_49 PAP2 superfamily K19302 - 3.6.1.27 0.00000000000000000000000000000000007617 143.0
HFD3_k127_7142321_5 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008144,GO:0016874,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 555.0
HFD3_k127_7142321_50 EamA-like transporter family - - - 0.0000000000000000000000000000001253 136.0
HFD3_k127_7142321_51 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000000000009926 126.0
HFD3_k127_7142321_52 Hydrogenase/urease nickel incorporation, metallochaperone, hypA K04651 - - 0.0000000000000000000000003116 108.0
HFD3_k127_7142321_53 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000001024 119.0
HFD3_k127_7142321_54 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.00000000000000000000001136 104.0
HFD3_k127_7142321_55 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000004906 91.0
HFD3_k127_7142321_56 Putative nucleotide-binding of sugar-metabolising enzyme K22129 - 2.7.1.219,2.7.1.220 0.000000000000006712 86.0
HFD3_k127_7142321_58 - - - - 0.000000000003587 73.0
HFD3_k127_7142321_59 NfeD-like C-terminal, partner-binding - - - 0.000002791 60.0
HFD3_k127_7142321_6 arsenical-resistance protein K03325,K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000597 534.0
HFD3_k127_7142321_60 Belongs to the UPF0312 family - - - 0.000004239 55.0
HFD3_k127_7142321_7 Phytanoyl-CoA dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 530.0
HFD3_k127_7142321_8 AIR synthase related protein, C-terminal domain K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 512.0
HFD3_k127_7142321_9 Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006357 484.0
HFD3_k127_7168295_0 E1-E2 ATPase K01533 - 3.6.3.4 1.188e-253 812.0
HFD3_k127_7168295_1 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 590.0
HFD3_k127_7168295_10 Sulfite exporter TauE/SafE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004596 252.0
HFD3_k127_7168295_11 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000006416 241.0
HFD3_k127_7168295_12 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001708 239.0
HFD3_k127_7168295_13 response to heat K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000003158 234.0
HFD3_k127_7168295_14 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000006948 209.0
HFD3_k127_7168295_15 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000884 211.0
HFD3_k127_7168295_16 - - - - 0.00000000000000000000000000000000000000000000000001484 183.0
HFD3_k127_7168295_17 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000003764 167.0
HFD3_k127_7168295_18 PFAM DsrC family protein K11179 - - 0.0000000000000000000000000000000000000000009613 165.0
HFD3_k127_7168295_19 MerR, DNA binding - - - 0.000000000000000000000000000000000001738 155.0
HFD3_k127_7168295_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007836 557.0
HFD3_k127_7168295_20 YCII-related domain - - - 0.000000000000000000000000000000000001796 141.0
HFD3_k127_7168295_21 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000002352 123.0
HFD3_k127_7168295_22 Rhodanese-related sulfurtransferase - - - 0.000000000000000000000000007347 115.0
HFD3_k127_7168295_23 Domain of unknown function DUF302 - - - 0.00000000000000000000000001596 118.0
HFD3_k127_7168295_24 Metal-sensitive transcriptional repressor - - - 0.00000000000000000000000002365 110.0
HFD3_k127_7168295_25 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000000000001727 111.0
HFD3_k127_7168295_26 Dimerisation domain - - - 0.0000000000006078 83.0
HFD3_k127_7168295_27 Copper binding proteins, plastocyanin/azurin family - - - 0.00009115 53.0
HFD3_k127_7168295_3 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000484 520.0
HFD3_k127_7168295_4 MMPL family K06994 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009624 450.0
HFD3_k127_7168295_5 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00529 - 1.18.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 400.0
HFD3_k127_7168295_6 transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 354.0
HFD3_k127_7168295_7 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006087 327.0
HFD3_k127_7168295_8 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002464 287.0
HFD3_k127_7168295_9 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001836 254.0
HFD3_k127_7192038_0 Multicopper oxidase - - - 1.072e-307 960.0
HFD3_k127_7192038_1 alpha-galactosidase K07407 - 3.2.1.22 2.187e-305 952.0
HFD3_k127_7192038_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 330.0
HFD3_k127_7192038_3 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 318.0
HFD3_k127_7192038_4 Binding-protein-dependent transport system inner membrane component K02025,K10118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001065 267.0
HFD3_k127_7192038_5 YjbR - - - 0.0000000000000000000000000000000000000000000000000001491 189.0
HFD3_k127_7226860_0 Glycosyltransferase like family 2 K20444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005729 296.0
HFD3_k127_7226860_1 Domain of unknown function (DUF222) - - - 0.0000000000000000314 82.0
HFD3_k127_7235441_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 1.39e-263 817.0
HFD3_k127_7235441_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 3.155e-259 812.0
HFD3_k127_7235441_10 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 - 3.4.21.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008069 394.0
HFD3_k127_7235441_11 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 386.0
HFD3_k127_7235441_12 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 394.0
HFD3_k127_7235441_13 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 378.0
HFD3_k127_7235441_14 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007011 368.0
HFD3_k127_7235441_15 MaoC like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004881 321.0
HFD3_k127_7235441_16 endonuclease III K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 316.0
HFD3_k127_7235441_17 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 299.0
HFD3_k127_7235441_18 phosphatase activity K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007177 287.0
HFD3_k127_7235441_19 inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004132 264.0
HFD3_k127_7235441_2 Acyl-CoA dehydrogenase, C-terminal domain K14448 - 1.3.8.12 4.643e-247 773.0
HFD3_k127_7235441_20 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000001565 234.0
HFD3_k127_7235441_21 Tellurite resistance protein TehB - - - 0.00000000000000000000000000000000000000000000000000000002141 205.0
HFD3_k127_7235441_22 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000006322 209.0
HFD3_k127_7235441_23 Two component transcriptional regulator, LuxR family - - - 0.0000000000000000000000000000000000000000000000000135 197.0
HFD3_k127_7235441_24 nucleotidyltransferase activity - - - 0.00000000000000000000000000000000000000000003565 172.0
HFD3_k127_7235441_25 - - - - 0.0000000000000000000000000000000001234 134.0
HFD3_k127_7235441_26 Methylamine utilisation protein MauE - - - 0.00000000000000000000001291 104.0
HFD3_k127_7235441_27 - - - - 0.000000000000002503 78.0
HFD3_k127_7235441_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K15372 - 2.6.1.55 7.829e-220 691.0
HFD3_k127_7235441_4 Evidence 4 Homologs of previously reported genes of - - - 1.729e-195 621.0
HFD3_k127_7235441_5 Ferredoxin oxidoreductase K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 572.0
HFD3_k127_7235441_6 HpcH/HpaI aldolase/citrate lyase family K01644,K08691 - 4.1.3.24,4.1.3.25,4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 570.0
HFD3_k127_7235441_7 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006169 541.0
HFD3_k127_7235441_8 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009527 512.0
HFD3_k127_7235441_9 Lysylphosphatidylglycerol synthase TM region K07027,K20468 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005418 419.0
HFD3_k127_7268634_0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 3.507e-213 672.0
HFD3_k127_7268634_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000137 270.0
HFD3_k127_7278545_0 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000008798 192.0
HFD3_k127_7278545_1 PFAM AhpC TSA family - - - 0.00000000000000000000000000004345 116.0
HFD3_k127_7327194_0 endonuclease activity - - - 0.0000000000000000000000000000000000000000000000003183 191.0
HFD3_k127_7341242_0 Belongs to the peptidase S8 family - - - 0.0 1375.0
HFD3_k127_7341242_1 efflux transmembrane transporter activity K02004 - - 3.658e-205 664.0
HFD3_k127_7341242_10 Thioredoxin-like domain K03671 - - 0.000000000000000000000000000000000000000000000008899 174.0
HFD3_k127_7341242_11 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000000000000001852 115.0
HFD3_k127_7341242_12 Rhodanese Homology Domain - - - 0.00000000000000000000000219 110.0
HFD3_k127_7341242_13 helix_turn_helix, cAMP Regulatory protein K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.0000000000000000004176 100.0
HFD3_k127_7341242_14 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000008575 88.0
HFD3_k127_7341242_15 2TM domain - - - 0.000000000002134 75.0
HFD3_k127_7341242_16 iron ion binding - - - 0.0009866 50.0
HFD3_k127_7341242_2 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 528.0
HFD3_k127_7341242_3 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 322.0
HFD3_k127_7341242_4 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 303.0
HFD3_k127_7341242_5 Glycosyl transferases group 1 K08256 - 2.4.1.345 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008854 300.0
HFD3_k127_7341242_6 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001256 269.0
HFD3_k127_7341242_7 transcriptional regulator K16137 - - 0.000000000000000000000000000000000000000000000000000000000000000009092 237.0
HFD3_k127_7341242_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000002734 203.0
HFD3_k127_7341242_9 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000001697 207.0
HFD3_k127_735961_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.17.4.1 0.0 1230.0
HFD3_k127_735961_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 8.531e-239 747.0
HFD3_k127_735961_10 COG0346 Lactoylglutathione lyase and related lyases K07032 - - 0.000000000000000000000000000000000000000000491 168.0
HFD3_k127_735961_11 OsmC-like protein - - - 0.000000000000000000000000000000003096 131.0
HFD3_k127_735961_12 - - - - 0.00000000000000000000000000004825 128.0
HFD3_k127_735961_13 Bulb-type mannose-specific lectin - - - 0.0006313 48.0
HFD3_k127_735961_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 1.308e-200 632.0
HFD3_k127_735961_3 Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 489.0
HFD3_k127_735961_4 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009674 345.0
HFD3_k127_735961_5 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000627 313.0
HFD3_k127_735961_6 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002813 271.0
HFD3_k127_735961_7 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000001229 250.0
HFD3_k127_735961_8 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000002317 205.0
HFD3_k127_735961_9 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000001563 189.0
HFD3_k127_7377801_0 Domain of unknown function (DUF3367) K16648 - - 0.0 1153.0
HFD3_k127_7377801_1 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004853 393.0
HFD3_k127_7377801_2 integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 372.0
HFD3_k127_7377801_3 3-methyladenine DNA glycosylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 346.0
HFD3_k127_7377801_4 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 323.0
HFD3_k127_7377801_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000223 225.0
HFD3_k127_7377801_6 Methyltransferase type 12 - - - 0.00000000000000000000000000000000000000001588 166.0
HFD3_k127_7377801_7 ECF sigma factor K03088 - - 0.0000000000004801 72.0
HFD3_k127_7399037_0 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006872 594.0
HFD3_k127_7399037_1 Protein of unknown function (DUF1272) K09984 - - 0.00000000000000000000000000000000000000000001819 177.0
HFD3_k127_7399037_2 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000002202 87.0
HFD3_k127_7409695_0 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000356 253.0
HFD3_k127_7409695_1 - - - - 0.00000000000000000000000000000000000000000003499 176.0
HFD3_k127_7409695_2 Peptidoglycan-binding domain 1 protein K07260,K21449 - 3.4.17.14 0.000000000000000000000000000000000001961 158.0
HFD3_k127_7409695_3 - - - - 0.000003216 60.0
HFD3_k127_7409695_5 Protein of unknown function (DUF2510) - - - 0.0006761 51.0
HFD3_k127_7458256_0 DNA photolyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 577.0
HFD3_k127_7458256_1 Protein of unknown function (DUF2867) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 491.0
HFD3_k127_7458256_10 Protein of unknown function (DUF998) - - - 0.0000000000000000000000000000000000000001438 161.0
HFD3_k127_7458256_11 Uncharacterised protein family UPF0066 - - - 0.00000000000000000000000000000001309 131.0
HFD3_k127_7458256_12 - K01992 - - 0.000000000000000144 89.0
HFD3_k127_7458256_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 499.0
HFD3_k127_7458256_3 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009442 467.0
HFD3_k127_7458256_4 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 424.0
HFD3_k127_7458256_5 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 407.0
HFD3_k127_7458256_6 B12 binding domain K22491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 356.0
HFD3_k127_7458256_7 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 339.0
HFD3_k127_7458256_8 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 302.0
HFD3_k127_7458256_9 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000008077 241.0
HFD3_k127_7489690_0 Heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 2.071e-211 664.0
HFD3_k127_7489690_1 Fe-S oxidoreductase - - - 2.994e-202 660.0
HFD3_k127_7489690_10 - - - - 0.000000000000000000000000000000000000000000000000000004513 202.0
HFD3_k127_7489690_11 - - - - 0.0000000000000000000000000000000000000004219 162.0
HFD3_k127_7489690_12 Glycine cleavage H-protein - - - 0.00000000000000000000000000000000003142 139.0
HFD3_k127_7489690_2 PFAM Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 561.0
HFD3_k127_7489690_3 FAD binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 518.0
HFD3_k127_7489690_4 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004734 475.0
HFD3_k127_7489690_5 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 407.0
HFD3_k127_7489690_6 Molybdopterin oxidoreductase K07812,K08352 - 1.7.2.3,1.8.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008397 392.0
HFD3_k127_7489690_7 PFAM Biotin lipoate A B protein ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003769 306.0
HFD3_k127_7489690_8 Elongator protein 3, MiaB family, Radical SAM K09711 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008237 243.0
HFD3_k127_7489690_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004141 244.0
HFD3_k127_756322_0 Fibronectin type 3 domain - - - 0.00000000000000000000000000000000000000000000000000004045 212.0
HFD3_k127_7642369_0 Protein of unknown function (DUF3500) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 414.0
HFD3_k127_7642369_1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K19189 - 1.14.13.10 0.0000000000000000000000000000000000000000000000000000000000000000000000002525 254.0
HFD3_k127_7656141_0 Dithiol-disulfide isomerase involved in polyketide biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000003639 245.0
HFD3_k127_7656141_1 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 - 2.2.1.9 0.000000000000000000000000000000000000000000000000005791 194.0
HFD3_k127_778880_0 GlcNAc-PI de-N-acetylase K18455 - 3.5.1.115 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 482.0
HFD3_k127_778880_1 YdjC-like protein K03478 - 3.5.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 406.0
HFD3_k127_778880_2 NADH pyrophosphatase-like rudimentary NUDIX domain K03426 - 3.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000002744 254.0
HFD3_k127_778880_3 nuclease K01174,K07038 - 3.1.31.1 0.0000000000000000000000000000000000000000000000000009786 190.0
HFD3_k127_778880_4 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000005439 134.0
HFD3_k127_778880_5 positive regulation of acetylcholine metabolic process K06910 - - 0.000000000000000000000000246 115.0
HFD3_k127_778929_0 KaiC K08482 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005369 492.0
HFD3_k127_778929_1 flavoprotein involved in K transport - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 468.0
HFD3_k127_778929_10 STAS domain - - - 0.00008006 51.0
HFD3_k127_778929_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 449.0
HFD3_k127_778929_3 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 327.0
HFD3_k127_778929_4 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002288 259.0
HFD3_k127_778929_5 aldo keto reductase - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000004386 255.0
HFD3_k127_778929_6 Pfam Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000000001547 203.0
HFD3_k127_778929_7 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000002418 195.0
HFD3_k127_778929_8 phosphorelay signal transduction system - - - 0.000000000000000000003587 104.0
HFD3_k127_778929_9 helix_turn_helix, mercury resistance K22491 - - 0.0000000001707 71.0
HFD3_k127_784935_0 HhH-GPD superfamily base excision DNA repair protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 287.0
HFD3_k127_784935_1 Glycosyl transferase, family 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000001818 208.0
HFD3_k127_784935_2 cellulose binding K07279 - - 0.000000000000000000000000000000000000000000000000003426 205.0
HFD3_k127_784935_3 calcium- and calmodulin-responsive adenylate cyclase activity K07260 - 3.4.17.14 0.0000000000000000000000000000000009811 150.0
HFD3_k127_784935_4 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000007103 75.0
HFD3_k127_791288_0 Phytanoyl-CoA dioxygenase (PhyH) K10674 - 1.14.11.55 0.0000000000000000000000000000000000000000000004144 174.0
HFD3_k127_791288_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000001962 109.0
HFD3_k127_81569_0 glutamine synthetase K01915 - 6.3.1.2 1.713e-233 729.0
HFD3_k127_81569_1 Amidohydrolase family - - - 2.222e-227 710.0
HFD3_k127_81569_2 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007227 464.0
HFD3_k127_81569_3 Belongs to the Glu Leu Phe Val dehydrogenases family K00270 - 1.4.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 388.0
HFD3_k127_81569_4 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 319.0
HFD3_k127_81569_5 decarboxylase K01593 - 4.1.1.105,4.1.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001136 269.0
HFD3_k127_81569_6 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000000000003652 130.0
HFD3_k127_81569_7 Acyltransferase family - - - 0.0000000001963 70.0
HFD3_k127_823940_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006121 542.0
HFD3_k127_823940_1 FAD dependent oxidoreductase K19746 - 1.4.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004451 301.0
HFD3_k127_823940_2 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000008599 234.0
HFD3_k127_823940_3 FCD - - - 0.00000000000000000000000000000000000000172 156.0
HFD3_k127_857896_0 Dehydratase family K01687 - 4.2.1.9 2.476e-299 925.0
HFD3_k127_857896_1 Belongs to the citrate synthase family K01647 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005235 593.0
HFD3_k127_857896_10 FMN-dependent dehydrogenase K00101 - 1.1.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 428.0
HFD3_k127_857896_11 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 388.0
HFD3_k127_857896_12 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 374.0
HFD3_k127_857896_13 ABC-type dipeptide transport system K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009398 359.0
HFD3_k127_857896_14 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 328.0
HFD3_k127_857896_15 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005366 313.0
HFD3_k127_857896_16 cheY-homologous receiver domain K07671 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004415 263.0
HFD3_k127_857896_17 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002616 261.0
HFD3_k127_857896_18 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001422 238.0
HFD3_k127_857896_19 Myo-inositol-1-phosphate synthase, GAPDH domain protein K01858 - 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000533 199.0
HFD3_k127_857896_2 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 593.0
HFD3_k127_857896_20 PFAM flavin reductase domain protein, FMN-binding - - - 0.00000000000000000000000000000000000000000000000000001232 203.0
HFD3_k127_857896_21 Histidine kinase K07655 GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019538,GO:0030312,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044110,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0046777,GO:0051704,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 0.000000000000000000000000000000000000000000000000602 194.0
HFD3_k127_857896_22 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K17735 - 1.1.1.108 0.000000000000000000000000000000000000000000000002357 190.0
HFD3_k127_857896_23 Protein of unknown function (DUF3054) - - - 0.000000000000000000000000001859 117.0
HFD3_k127_857896_24 PFAM 5-formyltetrahydrofolate cyclo-ligase K01934 - 6.3.3.2 0.000000000000000000000000005975 116.0
HFD3_k127_857896_25 ThiS family - - - 0.000000000000001762 81.0
HFD3_k127_857896_26 - - - - 0.00002534 52.0
HFD3_k127_857896_3 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004903 580.0
HFD3_k127_857896_4 acyl-CoA dehydrogenase K00248,K00249 - 1.3.8.1,1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 530.0
HFD3_k127_857896_5 COG1042 Acyl-CoA synthetase (NDP forming) K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007731 527.0
HFD3_k127_857896_6 AMP-binding enzyme C-terminal domain K02182 - 6.2.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000067 518.0
HFD3_k127_857896_7 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006607 474.0
HFD3_k127_857896_8 beta-keto acid cleavage enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 462.0
HFD3_k127_857896_9 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 425.0
HFD3_k127_864422_0 Uncharacterised protein family (UPF0182) K09118 - - 2.349e-284 902.0
HFD3_k127_864422_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 532.0
HFD3_k127_864422_10 PBS lyase HEAT-like repeat - - - 0.00000000000000000000000000000000000000000000000000000000000614 213.0
HFD3_k127_864422_11 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.0000000000000000000000000000000000000000000000000001033 196.0
HFD3_k127_864422_12 Belongs to the peptidase S16 family K07177 - - 0.000000000000000000000000000000000000000000000000008535 189.0
HFD3_k127_864422_13 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000002768 167.0
HFD3_k127_864422_14 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000003208 171.0
HFD3_k127_864422_15 nuclear chromosome segregation K19765 - - 0.0000000000000000114 96.0
HFD3_k127_864422_17 - - - - 0.00000008592 59.0
HFD3_k127_864422_18 Belongs to the peptidase S16 family K07177 - - 0.0005216 51.0
HFD3_k127_864422_2 regulation of cell shape K04074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 511.0
HFD3_k127_864422_3 PAC2 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 384.0
HFD3_k127_864422_4 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 372.0
HFD3_k127_864422_5 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000825 367.0
HFD3_k127_864422_6 Hydrolase of X-linked nucleoside diphosphate N terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 351.0
HFD3_k127_864422_7 Chlorite dismutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008267 263.0
HFD3_k127_864422_8 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000006118 246.0
HFD3_k127_864422_9 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000001081 226.0
HFD3_k127_885335_0 Biotin carboxylase C-terminal domain - - - 1.124e-233 738.0
HFD3_k127_885335_1 Flavin-binding monooxygenase-like K14520 - 1.14.13.84 5.593e-197 634.0
HFD3_k127_885335_10 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 301.0
HFD3_k127_885335_11 Biopterin-dependent aromatic amino acid hydroxylase K00500 - 1.14.16.1 0.00000000000000000000000000000000000000000000000000000000000000000000000001293 259.0
HFD3_k127_885335_12 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007248 263.0
HFD3_k127_885335_13 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002845 251.0
HFD3_k127_885335_14 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.00000000000000000000000000000000000000000000000000000000008688 209.0
HFD3_k127_885335_15 helix_turn_helix ASNC type - - - 0.00000000000000000000000000000000006033 140.0
HFD3_k127_885335_16 CoA binding domain - - - 0.0000000000000000000002631 110.0
HFD3_k127_885335_17 glyoxalase III activity - GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944 - 0.000000000001145 74.0
HFD3_k127_885335_2 alcohol dehydrogenase K00153 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.306 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 608.0
HFD3_k127_885335_3 DegT/DnrJ/EryC1/StrS aminotransferase family K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004354 545.0
HFD3_k127_885335_4 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K20940 - 1.14.13.218 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008559 471.0
HFD3_k127_885335_5 DNA primase, small subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008418 443.0
HFD3_k127_885335_6 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015 - 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 424.0
HFD3_k127_885335_7 Homocysteine S-methyltransferase K00544,K00548 - 2.1.1.13,2.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 404.0
HFD3_k127_885335_8 F420-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 387.0
HFD3_k127_885335_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 306.0
HFD3_k127_900621_0 ABC transporter - - - 3.015e-301 932.0
HFD3_k127_900621_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 3.398e-244 769.0
HFD3_k127_900621_10 inositol monophosphatase K01082 - 3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 342.0
HFD3_k127_900621_11 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures K07503 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008937 306.0
HFD3_k127_900621_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008847 323.0
HFD3_k127_900621_13 mannose-6-phosphate isomerase K01809 - 5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008324 276.0
HFD3_k127_900621_14 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004661 268.0
HFD3_k127_900621_15 Phosphorylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000003317 222.0
HFD3_k127_900621_16 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000001504 205.0
HFD3_k127_900621_17 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000007873 126.0
HFD3_k127_900621_18 Urate oxidase N-terminal - - - 0.00000000000000000000000135 119.0
HFD3_k127_900621_19 - - - - 0.000000000005279 79.0
HFD3_k127_900621_2 ABC1 family - - - 1.131e-243 765.0
HFD3_k127_900621_3 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 6.456e-211 666.0
HFD3_k127_900621_4 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 515.0
HFD3_k127_900621_5 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 443.0
HFD3_k127_900621_6 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 412.0
HFD3_k127_900621_7 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 370.0
HFD3_k127_900621_8 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005908 376.0
HFD3_k127_900621_9 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 354.0
HFD3_k127_954172_0 glycine cleavage T protein (aminomethyl transferase) K19191 - 1.5.3.19 0.0 1103.0
HFD3_k127_954172_1 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 4.278e-282 884.0
HFD3_k127_954172_10 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006467 451.0
HFD3_k127_954172_11 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 459.0
HFD3_k127_954172_12 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 454.0
HFD3_k127_954172_13 unsaturated fatty acid biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 442.0
HFD3_k127_954172_14 Zn-dependent oxidoreductase, NADPH quinone reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 413.0
HFD3_k127_954172_15 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008789 412.0
HFD3_k127_954172_16 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000666 400.0
HFD3_k127_954172_17 Daunorubicin resistance ABC transporter ATP-binding subunit K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 383.0
HFD3_k127_954172_18 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 369.0
HFD3_k127_954172_19 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 360.0
HFD3_k127_954172_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 5.076e-217 692.0
HFD3_k127_954172_20 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004718 359.0
HFD3_k127_954172_21 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 324.0
HFD3_k127_954172_22 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 317.0
HFD3_k127_954172_23 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005365 316.0
HFD3_k127_954172_24 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009017 311.0
HFD3_k127_954172_25 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 311.0
HFD3_k127_954172_26 Peptidase family M48 K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 308.0
HFD3_k127_954172_27 belongs to the urease gamma subunit family K14048 - 3.5.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 303.0
HFD3_k127_954172_28 Esterase-like activity of phytase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004384 291.0
HFD3_k127_954172_29 Esterase K03928 - 3.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007911 282.0
HFD3_k127_954172_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 6.091e-207 672.0
HFD3_k127_954172_30 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001167 295.0
HFD3_k127_954172_31 isochorismatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001637 276.0
HFD3_k127_954172_32 Tetrapyrrole (Corrin/Porphyrin) Methylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001888 277.0
HFD3_k127_954172_33 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000054 284.0
HFD3_k127_954172_34 Sterol carrier protein domain - GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008080,GO:0008150,GO:0008152,GO:0009056,GO:0009605,GO:0009607,GO:0009987,GO:0010941,GO:0016137,GO:0016139,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016999,GO:0017001,GO:0017144,GO:0030647,GO:0030649,GO:0031347,GO:0031349,GO:0032101,GO:0032103,GO:0034069,GO:0035821,GO:0040007,GO:0042802,GO:0043067,GO:0043207,GO:0044003,GO:0044068,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044248,GO:0044403,GO:0044419,GO:0044531,GO:0048518,GO:0048583,GO:0048584,GO:0050727,GO:0050729,GO:0050789,GO:0050794,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052032,GO:0052035,GO:0052040,GO:0052164,GO:0052167,GO:0052173,GO:0052200,GO:0052248,GO:0052255,GO:0052256,GO:0052259,GO:0052303,GO:0052306,GO:0052509,GO:0052510,GO:0052550,GO:0052552,GO:0052553,GO:0052564,GO:0052567,GO:0052572,GO:0065007,GO:0071704,GO:0075136,GO:0080134,GO:1901135,GO:1901136,GO:1901575,GO:1901657,GO:1901658 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002003 278.0
HFD3_k127_954172_35 N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001011 266.0
HFD3_k127_954172_36 Enoyl-CoA hydratase/isomerase K08299 - 4.2.1.149 0.000000000000000000000000000000000000000000000000000000000000000000000000001256 264.0
HFD3_k127_954172_37 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001024 253.0
HFD3_k127_954172_38 Catalyzes the synthesis of activated sulfate K00860,K00958 - 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000001379 247.0
HFD3_k127_954172_39 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002765 252.0
HFD3_k127_954172_4 Peptidase dimerisation domain - - - 2.822e-201 638.0
HFD3_k127_954172_40 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000001718 238.0
HFD3_k127_954172_41 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000005891 242.0
HFD3_k127_954172_42 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000005298 235.0
HFD3_k127_954172_43 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000000000001965 226.0
HFD3_k127_954172_44 histidine kinase, dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000000000000000000000000000000000000006339 245.0
HFD3_k127_954172_45 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000002333 226.0
HFD3_k127_954172_46 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000002406 217.0
HFD3_k127_954172_47 competence protein COMEC - - - 0.00000000000000000000000000000000000000000000000000000000205 213.0
HFD3_k127_954172_48 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.00000000000000000000000000000000000000000000000004357 182.0
HFD3_k127_954172_49 4fe-4S ferredoxin, iron-sulfur binding domain protein K03616 - - 0.00000000000000000000000000000000000000000000005421 181.0
HFD3_k127_954172_5 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006793,GO:0006796,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:0071944,GO:1902494,GO:1902503,GO:1990234 2.7.1.25,2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008651 579.0
HFD3_k127_954172_50 PFAM Carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000005639 179.0
HFD3_k127_954172_51 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000009222 168.0
HFD3_k127_954172_52 YjbR - - - 0.000000000000000000000000000000000000000001103 159.0
HFD3_k127_954172_53 Subtilase family - - - 0.0000000000000000000000000000000000000003658 167.0
HFD3_k127_954172_54 YCII-related domain - - - 0.00000000000000000000000000000000000001299 151.0
HFD3_k127_954172_55 Secreted repeat of unknown function - - - 0.0000000000000000000000000000000001003 139.0
HFD3_k127_954172_56 YCII-related domain - - - 0.0000000000000000000000000000001882 126.0
HFD3_k127_954172_57 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000002259 135.0
HFD3_k127_954172_58 regulatory protein, arsR K03892 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000005728 134.0
HFD3_k127_954172_59 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.000000000000000000000000001538 124.0
HFD3_k127_954172_6 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 559.0
HFD3_k127_954172_60 Sulfotransferase domain - - - 0.000000000000000000000000001843 123.0
HFD3_k127_954172_61 Anti-sigma-K factor rskA - - - 0.000000000000000000000000002898 118.0
HFD3_k127_954172_62 Universal stress protein - - - 0.00000000000000000000000003409 115.0
HFD3_k127_954172_63 PFAM Acetyltransferase (GNAT) family - - - 0.0000000000000000000000005868 111.0
HFD3_k127_954172_64 GYD domain - - - 0.000000000000000000000006605 106.0
HFD3_k127_954172_65 PFAM Prenyltransferase squalene oxidase - - - 0.000000000000000000004713 103.0
HFD3_k127_954172_66 - - - - 0.00000000000000000003875 107.0
HFD3_k127_954172_67 PFAM Prenyltransferase squalene oxidase - - - 0.000000000000007305 87.0
HFD3_k127_954172_68 ABC-2 family transporter protein K01992 - - 0.00000000000001262 85.0
HFD3_k127_954172_69 CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.00000000000302 68.0
HFD3_k127_954172_7 sulphate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 546.0
HFD3_k127_954172_70 Peptidoglycan-binding domain-containing protein - - - 0.000000743 59.0
HFD3_k127_954172_71 Belongs to the UPF0312 family - - - 0.00002808 55.0
HFD3_k127_954172_8 Sarcosine oxidase beta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 463.0
HFD3_k127_954172_9 Phosphoadenosine phosphosulfate reductase family K00957 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 456.0