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Overview

ID MAG01693
Name HFD3_bin.36
Sample SMP0045
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Blastocatellia
Order Pyrinomonadales
Family Pyrinomonadaceae
Genus PSRF01
Species
Assembly information
Completeness (%) 95.09
Contamination (%) 0.06
GC content (%) 56.0
N50 (bp) 36,780
Genome size (bp) 6,068,921

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes4581

Gene name Description KEGG GOs EC E-value Score Sequence
HFD3_k127_1045257_0 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 386.0
HFD3_k127_1045257_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003392 349.0
HFD3_k127_1045257_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001283 263.0
HFD3_k127_1045257_3 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000001735 156.0
HFD3_k127_1045257_4 - - - - 0.000000000000000000000001032 107.0
HFD3_k127_1053924_0 40-residue YVTN family beta-propeller repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007004 481.0
HFD3_k127_1053924_1 Putative glutamine amidotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005695 434.0
HFD3_k127_1053924_2 Peptidase C14 caspase catalytic subunit p20 - - - 0.000000000000000000000000000000000000000000000001784 186.0
HFD3_k127_105396_0 cellulose binding - - - 0.0 1318.0
HFD3_k127_105396_1 Radical SAM - - - 1e-323 1003.0
HFD3_k127_105396_10 Acyclic terpene utilisation family protein AtuA - - - 1.868e-214 673.0
HFD3_k127_105396_11 FtsX-like permease family - - - 4.444e-213 692.0
HFD3_k127_105396_12 MacB-like periplasmic core domain - - - 5.185e-208 674.0
HFD3_k127_105396_13 efflux transmembrane transporter activity K02004 - - 3.577e-205 666.0
HFD3_k127_105396_14 efflux transmembrane transporter activity K02004 - - 1.493e-204 664.0
HFD3_k127_105396_15 efflux transmembrane transporter activity - - - 4.877e-201 653.0
HFD3_k127_105396_16 efflux transmembrane transporter activity K02004 - - 8.742e-199 649.0
HFD3_k127_105396_17 efflux transmembrane transporter activity K02004 - - 1.124e-197 643.0
HFD3_k127_105396_18 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000659 642.0
HFD3_k127_105396_19 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003026 603.0
HFD3_k127_105396_2 Domain of unknown function (DUF5117) - - - 1.42e-296 931.0
HFD3_k127_105396_20 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005992 602.0
HFD3_k127_105396_21 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 597.0
HFD3_k127_105396_22 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004258 594.0
HFD3_k127_105396_23 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 590.0
HFD3_k127_105396_24 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 584.0
HFD3_k127_105396_25 PFAM type II secretion system protein E K02283,K03609 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005083 564.0
HFD3_k127_105396_26 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003111 566.0
HFD3_k127_105396_27 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 541.0
HFD3_k127_105396_28 ABC transporter K10441 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 538.0
HFD3_k127_105396_29 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 553.0
HFD3_k127_105396_3 efflux transmembrane transporter activity - - - 9.35e-253 803.0
HFD3_k127_105396_30 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 527.0
HFD3_k127_105396_31 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 494.0
HFD3_k127_105396_32 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007275 454.0
HFD3_k127_105396_33 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 437.0
HFD3_k127_105396_34 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004855 417.0
HFD3_k127_105396_35 ABC-type sugar transport system periplasmic component K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000627 400.0
HFD3_k127_105396_36 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007547 386.0
HFD3_k127_105396_37 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 350.0
HFD3_k127_105396_38 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 355.0
HFD3_k127_105396_39 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 325.0
HFD3_k127_105396_4 FtsX-like permease family - - - 5.799e-243 776.0
HFD3_k127_105396_40 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 310.0
HFD3_k127_105396_41 SNARE associated Golgi protein K01077 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 292.0
HFD3_k127_105396_42 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000129 299.0
HFD3_k127_105396_43 Belongs to the GSP D family K02280 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004691 291.0
HFD3_k127_105396_44 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000001483 263.0
HFD3_k127_105396_45 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000002849 257.0
HFD3_k127_105396_46 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005562 267.0
HFD3_k127_105396_47 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000384 246.0
HFD3_k127_105396_48 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000001203 228.0
HFD3_k127_105396_49 Type II secretion system K12510 - - 0.0000000000000000000000000000000000000000000000000000000000008035 222.0
HFD3_k127_105396_5 MacB-like periplasmic core domain - - - 2.316e-238 760.0
HFD3_k127_105396_50 PFAM cobalamin B12-binding domain protein K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000001379 203.0
HFD3_k127_105396_51 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.00000000000000000000000000000000000000000000000000000196 202.0
HFD3_k127_105396_52 Belongs to the enoyl-CoA hydratase isomerase family K13766 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000004799 200.0
HFD3_k127_105396_53 type II secretion system protein K12511 - - 0.00000000000000000000000000000000000000000000000000001112 200.0
HFD3_k127_105396_54 NUBPL iron-transfer P-loop NTPase K02282 - - 0.00000000000000000000000000000000000000000000000000007108 203.0
HFD3_k127_105396_55 Multicopper oxidase K08100 - 1.3.3.5 0.000000000000000000000000000000000000000000007454 169.0
HFD3_k127_105396_56 - - - - 0.000000000000000000000000000000000000000002158 158.0
HFD3_k127_105396_57 protein involved in formate dehydrogenase formation K02380 - - 0.00000000000000000000000000000000000000005941 160.0
HFD3_k127_105396_58 PFAM Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000001091 145.0
HFD3_k127_105396_59 Belongs to the UPF0312 family - - - 0.000000000000000000000000005609 117.0
HFD3_k127_105396_6 efflux transmembrane transporter activity K02004 - - 3.214e-226 726.0
HFD3_k127_105396_60 Putative Flp pilus-assembly TadE/G-like - - - 0.0000000000000000000000001162 119.0
HFD3_k127_105396_61 PFAM peptidase A24A, prepilin type IV - - - 0.000000000000000007567 91.0
HFD3_k127_105396_62 Tetratricopeptide repeat - - - 0.0000000000000003762 89.0
HFD3_k127_105396_63 TadE-like protein - - - 0.000000000000001386 84.0
HFD3_k127_105396_64 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.000000000000002603 78.0
HFD3_k127_105396_65 efflux transmembrane transporter activity - - - 0.0000000000007309 70.0
HFD3_k127_105396_66 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K08348 - 1.17.1.9,1.17.5.3 0.000000000004817 65.0
HFD3_k127_105396_67 Glycosyltransferase family 87 - - - 0.00000000003474 76.0
HFD3_k127_105396_68 - - - - 0.0000003811 61.0
HFD3_k127_105396_69 TadE-like protein - - - 0.00002984 52.0
HFD3_k127_105396_7 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 4.047e-226 713.0
HFD3_k127_105396_70 Flp Fap pilin component K02651 - - 0.00003401 48.0
HFD3_k127_105396_71 aminopeptidase activity - - - 0.0000344 48.0
HFD3_k127_105396_72 Flp Fap pilin component K02651 - - 0.00004319 48.0
HFD3_k127_105396_73 Flp Fap pilin component K02651 - - 0.0000568 48.0
HFD3_k127_105396_74 - - - - 0.00007119 53.0
HFD3_k127_105396_75 SMART Tetratricopeptide domain protein - - - 0.00009279 54.0
HFD3_k127_105396_8 MacB-like periplasmic core domain - - - 1.068e-217 701.0
HFD3_k127_105396_9 MacB-like periplasmic core domain - - - 2.522e-215 694.0
HFD3_k127_1061952_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1101.0
HFD3_k127_1061952_1 GTP-binding protein TypA K06207 - - 8.782e-261 815.0
HFD3_k127_1061952_10 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 415.0
HFD3_k127_1061952_11 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000727 372.0
HFD3_k127_1061952_12 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 369.0
HFD3_k127_1061952_13 von Willebrand factor (vWF) type A domain K02448 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007959 336.0
HFD3_k127_1061952_14 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 299.0
HFD3_k127_1061952_15 with different specificities (related to short-chain alcohol K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009006 276.0
HFD3_k127_1061952_16 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000002433 233.0
HFD3_k127_1061952_17 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000559 226.0
HFD3_k127_1061952_18 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000005459 179.0
HFD3_k127_1061952_19 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000007811 160.0
HFD3_k127_1061952_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 9.031e-223 702.0
HFD3_k127_1061952_20 Tricorn protease C1 domain K03797 - 3.4.21.102 0.00000000000000000000000000000000000000009496 168.0
HFD3_k127_1061952_21 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000000003526 113.0
HFD3_k127_1061952_22 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000003271 95.0
HFD3_k127_1061952_23 PFAM oxidoreductase domain protein - - - 0.0000000002476 67.0
HFD3_k127_1061952_24 TPR repeat-containing protein - - - 0.00000002653 66.0
HFD3_k127_1061952_25 Pilus assembly protein K02663 - - 0.0000002904 60.0
HFD3_k127_1061952_26 peptidyl-tyrosine sulfation - - - 0.00001953 56.0
HFD3_k127_1061952_27 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00002414 55.0
HFD3_k127_1061952_28 Involved in the tonB-independent uptake of proteins - - - 0.00003869 55.0
HFD3_k127_1061952_29 general secretion pathway protein K02456,K02650 - - 0.00004703 54.0
HFD3_k127_1061952_3 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 3.765e-198 630.0
HFD3_k127_1061952_4 Hydantoinase/oxoprolinase K01473 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 597.0
HFD3_k127_1061952_5 Belongs to the ClpA ClpB family K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008521 516.0
HFD3_k127_1061952_6 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003794 495.0
HFD3_k127_1061952_7 Natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007355 445.0
HFD3_k127_1061952_8 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009372 420.0
HFD3_k127_1061952_9 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 415.0
HFD3_k127_107619_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K17050 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0042126,GO:0043436,GO:0043546,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0097159,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 0.0 1801.0
HFD3_k127_107619_1 TonB-dependent receptor - - - 0.0 1483.0
HFD3_k127_107619_10 ATPase involved in DNA repair - - - 8.295e-220 724.0
HFD3_k127_107619_11 Polysulphide reductase, NrfD K00185 - - 1.066e-210 667.0
HFD3_k127_107619_12 peptidase - - - 3.225e-199 639.0
HFD3_k127_107619_13 Spermine/spermidine synthase domain - - - 2.158e-196 637.0
HFD3_k127_107619_14 - - - - 9.853e-196 626.0
HFD3_k127_107619_15 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 626.0
HFD3_k127_107619_16 Isoleucyl-tRNA synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004528 586.0
HFD3_k127_107619_17 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000399 521.0
HFD3_k127_107619_18 AAA domain (dynein-related subfamily) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002892 486.0
HFD3_k127_107619_19 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 475.0
HFD3_k127_107619_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1411.0
HFD3_k127_107619_20 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000591 484.0
HFD3_k127_107619_21 Major Facilitator Superfamily K02575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 407.0
HFD3_k127_107619_22 Radical SAM superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 364.0
HFD3_k127_107619_23 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009602 333.0
HFD3_k127_107619_24 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 315.0
HFD3_k127_107619_26 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 316.0
HFD3_k127_107619_27 thioesterase involved in non-ribosomal peptide biosynthesis K01071 - 3.1.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 287.0
HFD3_k127_107619_28 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001083 306.0
HFD3_k127_107619_29 competence protein COMEC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001283 261.0
HFD3_k127_107619_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0 1245.0
HFD3_k127_107619_30 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000002193 237.0
HFD3_k127_107619_31 nitrate reductase activity K00370,K00374,K02575 GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006950,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009628,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0036293,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0055114,GO:0070469,GO:0070470,GO:0070482,GO:0071944,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000024 229.0
HFD3_k127_107619_32 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000007358 219.0
HFD3_k127_107619_33 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000006993 225.0
HFD3_k127_107619_34 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000000001648 205.0
HFD3_k127_107619_35 Glyoxalase-like domain K08234 - - 0.000000000000000000000000000000000000000000000000000000005139 202.0
HFD3_k127_107619_36 PFAM Glycosyl transferase family 2 K14597 - - 0.000000000000000000000000000000000000000000000000000001685 207.0
HFD3_k127_107619_37 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000003016 187.0
HFD3_k127_107619_38 Common central domain of tyrosinase K00505 - 1.14.18.1 0.00000000000000000000000000000000000000000000001551 191.0
HFD3_k127_107619_39 Cytochrome c - - - 0.00000000000000000000000000000000000000000000003727 175.0
HFD3_k127_107619_4 cellulose binding - - - 0.0 1080.0
HFD3_k127_107619_40 Belongs to the peptidase S1B family K01318 - 3.4.21.19 0.0000000000000000000000000000000000000000000007411 177.0
HFD3_k127_107619_41 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000003873 171.0
HFD3_k127_107619_42 Cytochrome c - - - 0.00000000000000000000000000000000000000000001151 174.0
HFD3_k127_107619_43 cytochrome c - - - 0.0000000000000000000000000000000000000000002381 165.0
HFD3_k127_107619_44 Bacterial SH3 domain - - - 0.000000000000000000000000000000000000000003797 169.0
HFD3_k127_107619_45 - - - - 0.00000000000000000000000000000000000000001873 175.0
HFD3_k127_107619_46 response to oxidative stress - - - 0.00000000000000000000000000000000000000005795 155.0
HFD3_k127_107619_47 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000001262 141.0
HFD3_k127_107619_48 - - - - 0.0000000000000000000000000000001093 128.0
HFD3_k127_107619_49 Protein of unknown function (DUF3303) - - - 0.0000000000000000000000000000004637 125.0
HFD3_k127_107619_5 4Fe-4S dicluster domain K00184 - - 3.983e-264 844.0
HFD3_k127_107619_50 DNA-binding transcription factor activity K03892 - - 0.000000000000000000000000000002707 123.0
HFD3_k127_107619_51 protein histidine kinase activity K06375 - - 0.0000000000000000000000000001075 123.0
HFD3_k127_107619_52 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.00000000000000000000001045 108.0
HFD3_k127_107619_53 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.0000000000000000000001853 103.0
HFD3_k127_107619_54 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.000000000000000000001012 99.0
HFD3_k127_107619_55 Protein of unknown function (DUF2892) - - - 0.00000000000000000001407 92.0
HFD3_k127_107619_56 Di-iron-containing protein involved in the repair of iron-sulfur clusters - - - 0.0000000000000000005479 93.0
HFD3_k127_107619_57 DinB family - - - 0.000000000000000001247 93.0
HFD3_k127_107619_58 - - - - 0.0000000000001328 77.0
HFD3_k127_107619_59 Selenoprotein B glycine betaine sarcosine D-proline reductase K10794 - 1.21.4.1 0.000000001032 64.0
HFD3_k127_107619_6 Belongs to the glycosyl hydrolase 2 family K01195 - 3.2.1.31 1.128e-259 814.0
HFD3_k127_107619_61 Parallel beta-helix repeats - - - 0.00002092 58.0
HFD3_k127_107619_62 Peptide synthetase - - - 0.0001032 45.0
HFD3_k127_107619_63 beta-galactosidase activity - - - 0.0001098 55.0
HFD3_k127_107619_64 RNA polymerase Rpb6 - - - 0.0001415 48.0
HFD3_k127_107619_65 AMP-binding enzyme - - - 0.0001496 44.0
HFD3_k127_107619_66 ATPase histidine kinase DNA gyrase B HSP90 domain protein - - - 0.0005446 45.0
HFD3_k127_107619_7 ribosome binding - - - 1.032e-234 761.0
HFD3_k127_107619_8 nitrate reductase beta subunit K00371 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0033554,GO:0042126,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 2.651e-226 711.0
HFD3_k127_107619_9 SMART Elongator protein 3 MiaB NifB - - - 2.482e-225 711.0
HFD3_k127_115415_0 Peptidase family M28 - - - 1.143e-247 777.0
HFD3_k127_115415_1 COG2346, Truncated hemoglobins K06886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001073 250.0
HFD3_k127_115415_2 Voltage gated chloride channel - - - 0.00000000000000000000000000000000000000000000002336 175.0
HFD3_k127_115415_3 Hemerythrin hhe cation binding - - - 0.00000000000000000000000000000000004891 138.0
HFD3_k127_1168333_0 Belongs to the ClpA ClpB family K03696 - - 0.0 1077.0
HFD3_k127_1168333_1 Multicopper oxidase - - - 0.0 1033.0
HFD3_k127_1168333_10 Thiolase, C-terminal domain K00632 - 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 540.0
HFD3_k127_1168333_100 unfolded protein binding K06142 GO:0001530,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0006807,GO:0008104,GO:0008150,GO:0008152,GO:0008289,GO:0009279,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0019867,GO:0022417,GO:0022607,GO:0030288,GO:0030312,GO:0030313,GO:0031647,GO:0031975,GO:0032978,GO:0033036,GO:0034613,GO:0042597,GO:0042802,GO:0043163,GO:0043165,GO:0043170,GO:0044085,GO:0044091,GO:0044238,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0050821,GO:0051082,GO:0051179,GO:0051205,GO:0051234,GO:0051604,GO:0051641,GO:0061024,GO:0061077,GO:0065007,GO:0065008,GO:0070727,GO:0071704,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0097367,GO:1901564 - 0.000001569 58.0
HFD3_k127_1168333_102 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000007653 50.0
HFD3_k127_1168333_103 - - - - 0.00001188 59.0
HFD3_k127_1168333_104 Outer membrane protein (OmpH-like) K06142 - - 0.00003463 54.0
HFD3_k127_1168333_105 Recombinase zinc beta ribbon domain - - - 0.00004649 48.0
HFD3_k127_1168333_106 Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides - - - 0.0002085 54.0
HFD3_k127_1168333_11 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 551.0
HFD3_k127_1168333_12 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 502.0
HFD3_k127_1168333_13 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007462 507.0
HFD3_k127_1168333_14 NAD(P) transhydrogenase beta subunit K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 478.0
HFD3_k127_1168333_15 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 476.0
HFD3_k127_1168333_16 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004105 455.0
HFD3_k127_1168333_17 Multicopper oxidase K00368,K22349 - 1.16.3.3,1.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 469.0
HFD3_k127_1168333_18 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008239 450.0
HFD3_k127_1168333_19 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 451.0
HFD3_k127_1168333_2 Carboxypeptidase regulatory-like domain - - - 4.037e-287 916.0
HFD3_k127_1168333_20 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 447.0
HFD3_k127_1168333_21 TIGRFAM outer membrane protein assembly complex, YaeT protein K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005531 464.0
HFD3_k127_1168333_22 Aldehyde dehydrogenase family K22445 - 1.2.99.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 428.0
HFD3_k127_1168333_23 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 415.0
HFD3_k127_1168333_24 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 412.0
HFD3_k127_1168333_25 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009412 411.0
HFD3_k127_1168333_26 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 402.0
HFD3_k127_1168333_27 Peptidase family S41 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008145 413.0
HFD3_k127_1168333_28 PFAM Alanine dehydrogenase PNT, C-terminal domain K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008447 371.0
HFD3_k127_1168333_29 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 353.0
HFD3_k127_1168333_3 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K07516 - 1.1.1.35 4.236e-285 897.0
HFD3_k127_1168333_30 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005042 352.0
HFD3_k127_1168333_31 Subtilase family K14645 GO:0005575,GO:0005576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 350.0
HFD3_k127_1168333_32 Peptidase family M1 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 352.0
HFD3_k127_1168333_33 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005491 331.0
HFD3_k127_1168333_34 PFAM Peptidase M16 inactive domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 314.0
HFD3_k127_1168333_35 Protein of unknown function (DUF1009) K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 304.0
HFD3_k127_1168333_36 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 300.0
HFD3_k127_1168333_37 thiolester hydrolase activity K01179,K06889,K10773,K15853 - 3.2.1.4,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 295.0
HFD3_k127_1168333_38 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007712 286.0
HFD3_k127_1168333_39 Peptidase M16 inactive domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 299.0
HFD3_k127_1168333_4 PFAM TonB-dependent Receptor Plug K02014,K16089 - - 6.203e-214 686.0
HFD3_k127_1168333_40 Biopterin-dependent aromatic amino acid hydroxylase K00500 - 1.14.16.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001604 286.0
HFD3_k127_1168333_41 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004616 287.0
HFD3_k127_1168333_42 Glutamine amidotransferases class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002236 283.0
HFD3_k127_1168333_43 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007938 282.0
HFD3_k127_1168333_45 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000007185 269.0
HFD3_k127_1168333_46 DNA ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000003311 266.0
HFD3_k127_1168333_47 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001985 253.0
HFD3_k127_1168333_48 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002202 258.0
HFD3_k127_1168333_49 Predicted membrane protein (DUF2339) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003768 267.0
HFD3_k127_1168333_5 Peptidase family M49 - - - 1.905e-211 670.0
HFD3_k127_1168333_50 Haemolysin-III related K11068 - - 0.00000000000000000000000000000000000000000000000000000000000000000001108 239.0
HFD3_k127_1168333_51 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000001499 244.0
HFD3_k127_1168333_52 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000451 236.0
HFD3_k127_1168333_53 ABC-type transport system involved in lipoprotein release permease component K02004,K09808 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0098796,GO:0098797,GO:1990778 - 0.000000000000000000000000000000000000000000000000000000000000000005208 240.0
HFD3_k127_1168333_54 Transporter, small conductance mechanosensitive ion channel MscS family protein K03442 - - 0.000000000000000000000000000000000000000000000000000000000001022 222.0
HFD3_k127_1168333_55 membrane - - - 0.0000000000000000000000000000000000000000000000000000000002105 220.0
HFD3_k127_1168333_56 SCO1/SenC - - - 0.0000000000000000000000000000000000000000000000000000007301 201.0
HFD3_k127_1168333_57 Zn-dependent hydrolase, glyoxylase - - - 0.000000000000000000000000000000000000000000000000000002258 202.0
HFD3_k127_1168333_58 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000985 192.0
HFD3_k127_1168333_59 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000002956 203.0
HFD3_k127_1168333_6 Carboxypeptidase regulatory-like domain - - - 2.006e-195 626.0
HFD3_k127_1168333_60 Protein of unknown function (DUF1203) - - - 0.00000000000000000000000000000000000000000000000001205 186.0
HFD3_k127_1168333_61 FabA-like domain K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000003603 177.0
HFD3_k127_1168333_62 Bacterial regulatory proteins, tetR family K13770 - - 0.00000000000000000000000000000000000000000000003627 177.0
HFD3_k127_1168333_63 Domain of unknown function (DUF374) K09778 - - 0.0000000000000000000000000000000000000000001004 168.0
HFD3_k127_1168333_64 Methylates ribosomal protein L11 K02687 - - 0.000000000000000000000000000000000000000000944 167.0
HFD3_k127_1168333_65 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 0.000000000000000000000000000000000000000002703 164.0
HFD3_k127_1168333_66 YCII-related domain - - - 0.000000000000000000000000000000000000000003391 160.0
HFD3_k127_1168333_67 Recombinase - - - 0.0000000000000000000000000000000000000838 145.0
HFD3_k127_1168333_68 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000004224 156.0
HFD3_k127_1168333_69 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000000000000000000000000000000004646 142.0
HFD3_k127_1168333_7 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 625.0
HFD3_k127_1168333_70 UPF0314 protein - - - 0.0000000000000000000000000000000000005209 146.0
HFD3_k127_1168333_71 - - - - 0.000000000000000000000000000000000002067 158.0
HFD3_k127_1168333_72 Histidine kinase-like ATPase domain - - - 0.00000000000000000000000000000000002672 146.0
HFD3_k127_1168333_73 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.000000000000000000000000000000000172 135.0
HFD3_k127_1168333_74 STAS domain K04749 - - 0.00000000000000000000000000000000018 135.0
HFD3_k127_1168333_75 PDZ DHR GLGF domain protein - - - 0.000000000000000000000000000003967 132.0
HFD3_k127_1168333_76 PFAM oxidoreductase FAD NAD(P)-binding domain protein - - - 0.0000000000000000000000000009844 122.0
HFD3_k127_1168333_77 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.000000000000000000000000003207 116.0
HFD3_k127_1168333_78 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000004167 108.0
HFD3_k127_1168333_79 cheY-homologous receiver domain K11443 - - 0.00000000000000000000002504 104.0
HFD3_k127_1168333_8 Belongs to the HpcH HpaI aldolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 562.0
HFD3_k127_1168333_80 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.0000000000000000000003419 102.0
HFD3_k127_1168333_81 C4-type zinc ribbon domain K07164,K22391 - 3.5.4.16 0.00000000000000000006211 99.0
HFD3_k127_1168333_82 transposition K07497 - - 0.0000000000000000003501 89.0
HFD3_k127_1168333_83 Recombinase - - - 0.000000000000000001298 88.0
HFD3_k127_1168333_84 Protein of unknown function (DUF2933) - - - 0.00000000000000001425 84.0
HFD3_k127_1168333_85 - - - - 0.00000000000003289 87.0
HFD3_k127_1168333_86 Protein of unknown function (DUF3142) - - - 0.0000000000000353 85.0
HFD3_k127_1168333_87 repeat protein - - - 0.0000000000003817 71.0
HFD3_k127_1168333_88 Carboxypeptidase regulatory-like domain - - - 0.0000000000003988 83.0
HFD3_k127_1168333_89 Domain of unknown function (DUF4369) - - - 0.0000000000005645 80.0
HFD3_k127_1168333_9 Peptidase family M1 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007442 567.0
HFD3_k127_1168333_91 YceI-like domain - - - 0.00000000001045 73.0
HFD3_k127_1168333_92 COG1918 Fe2 transport system protein A K04758 - - 0.00000000001775 69.0
HFD3_k127_1168333_93 Tetratricopeptide repeat - - - 0.0000000006538 72.0
HFD3_k127_1168333_94 TPM domain K06872 - - 0.00000000514 70.0
HFD3_k127_1168333_95 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 0.000000005181 59.0
HFD3_k127_1168333_96 - - - - 0.000000007762 66.0
HFD3_k127_1168333_97 Carboxypeptidase regulatory-like domain - - - 0.0000001086 66.0
HFD3_k127_1168333_98 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000002427 65.0
HFD3_k127_1168333_99 Recombinase - - - 0.0000002848 56.0
HFD3_k127_1197486_0 transport - - - 0.0 1108.0
HFD3_k127_1197486_1 major pilin protein fima - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 429.0
HFD3_k127_1197486_10 O-Antigen ligase K18814 - - 0.000000000000000000006166 107.0
HFD3_k127_1197486_11 - - - - 0.000000000000000228 85.0
HFD3_k127_1197486_12 Interferon-induced transmembrane protein - - - 0.0000000000000003878 81.0
HFD3_k127_1197486_13 pathogenesis - - - 0.00000000002971 75.0
HFD3_k127_1197486_14 Domain of unknown function (DUF4129) - - - 0.00000000006398 74.0
HFD3_k127_1197486_15 Polysaccharide biosynthesis/export protein K01991 - - 0.00001188 57.0
HFD3_k127_1197486_2 Protein of unknown function (DUF512) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004829 325.0
HFD3_k127_1197486_3 PFAM sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 302.0
HFD3_k127_1197486_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000005851 236.0
HFD3_k127_1197486_5 Protein of unknown function (DUF354) K09726 - - 0.00000000000000000000000000000000000000000000000000000000000000000003003 244.0
HFD3_k127_1197486_6 PFAM Peptidase M20 - - - 0.0000000000000000000000000000000000000000000000000000001295 211.0
HFD3_k127_1197486_7 methyltransferase - - - 0.00000000000000000000000000000000000000000000008626 176.0
HFD3_k127_1197486_8 PFAM TM2 domain - - - 0.0000000000000000000000000000009128 126.0
HFD3_k127_1197486_9 Protein of unknown function (DUF2752) - - - 0.0000000000000000000000004 111.0
HFD3_k127_1246339_0 serine-type peptidase activity - - - 2.07e-261 828.0
HFD3_k127_1246339_1 Tetratricopeptide repeat - - - 6.602e-236 770.0
HFD3_k127_1246339_10 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000001877 187.0
HFD3_k127_1246339_12 PFAM glycosyl transferase family 39 K14340 - - 0.0000000000000000000000000000000000000000000002376 188.0
HFD3_k127_1246339_13 Putative lumazine-binding - - - 0.000000000000000000000000000000000000000001761 160.0
HFD3_k127_1246339_14 - - - - 0.000000000000000000000000000000000000000006485 159.0
HFD3_k127_1246339_15 SnoaL-like domain - - - 0.000000000000000000000000000000000000000178 156.0
HFD3_k127_1246339_16 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000001354 156.0
HFD3_k127_1246339_17 self proteolysis - - - 0.0000000000000000000000000000000001004 141.0
HFD3_k127_1246339_18 - - - - 0.00000000000000000000000000001359 123.0
HFD3_k127_1246339_19 - - - - 0.00000000000000000000000000002475 121.0
HFD3_k127_1246339_2 Flavin-binding monooxygenase-like - - - 5.763e-231 724.0
HFD3_k127_1246339_20 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000003091 124.0
HFD3_k127_1246339_21 - - - - 0.00000000000000000000000008219 123.0
HFD3_k127_1246339_22 Glucose Sorbosone dehydrogenase - - - 0.00000000000000000000005025 117.0
HFD3_k127_1246339_23 Acyltransferase family - - - 0.000000000000000000001178 108.0
HFD3_k127_1246339_24 - - - - 0.00000000000000000008532 93.0
HFD3_k127_1246339_25 - - - - 0.0000000001528 64.0
HFD3_k127_1246339_26 23S rRNA-intervening sequence protein - - - 0.000000001453 63.0
HFD3_k127_1246339_27 - - - - 0.0000009396 57.0
HFD3_k127_1246339_28 oxidoreductase activity - - - 0.000009733 58.0
HFD3_k127_1246339_29 - - - - 0.00003488 53.0
HFD3_k127_1246339_3 PFAM DNA methylase N-4 N-6 domain protein K00571 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 490.0
HFD3_k127_1246339_4 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 327.0
HFD3_k127_1246339_5 Chlorophyllase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 295.0
HFD3_k127_1246339_6 LytTr DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001002 250.0
HFD3_k127_1246339_7 Protein conserved in bacteria K20274 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002823 273.0
HFD3_k127_1246339_8 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000005973 243.0
HFD3_k127_1246339_9 NAD+ binding - - - 0.0000000000000000000000000000000000000000000000000000000000002712 228.0
HFD3_k127_1248336_0 Tricorn protease C1 domain K08676 - - 0.0 1271.0
HFD3_k127_1248336_1 PFAM Pyridoxal-dependent decarboxylase conserved domain K01580,K01593,K13745 - 4.1.1.105,4.1.1.15,4.1.1.28,4.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 568.0
HFD3_k127_1248336_10 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 296.0
HFD3_k127_1248336_11 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001865 286.0
HFD3_k127_1248336_12 3'(2'),5'-bisphosphate nucleotidase activity K01082 - 3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000002616 239.0
HFD3_k127_1248336_13 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation K16899 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000002512 252.0
HFD3_k127_1248336_14 Histidine kinase - - - 0.0000000000000000000000000000000001445 151.0
HFD3_k127_1248336_15 membrane - - - 0.0000000000000000000000000000000002704 134.0
HFD3_k127_1248336_16 Redoxin - - - 0.000000000000000000000000000000002307 134.0
HFD3_k127_1248336_17 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.0000000000000000000001277 100.0
HFD3_k127_1248336_18 von Willebrand factor, type A K07114 - - 0.000000000000000000002387 106.0
HFD3_k127_1248336_19 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000006834 95.0
HFD3_k127_1248336_2 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 569.0
HFD3_k127_1248336_20 Belongs to the 'phage' integrase family - - - 0.00000000599 60.0
HFD3_k127_1248336_21 SMART Transport-associated and nodulation region K04065 - - 0.00000007006 64.0
HFD3_k127_1248336_24 - - - - 0.0005907 48.0
HFD3_k127_1248336_3 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007179 553.0
HFD3_k127_1248336_4 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 490.0
HFD3_k127_1248336_5 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 455.0
HFD3_k127_1248336_6 Carboxymethylenebutenolidase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 451.0
HFD3_k127_1248336_7 PD-(D/E)XK nuclease superfamily K16898 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 441.0
HFD3_k127_1248336_8 Aminotransferase class-V K01556 - 3.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 357.0
HFD3_k127_1248336_9 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003646 321.0
HFD3_k127_1296007_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1323.0
HFD3_k127_1296007_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.146e-294 926.0
HFD3_k127_1296007_10 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.000359 49.0
HFD3_k127_1296007_2 Peptidase family M28 - - - 1.505e-209 668.0
HFD3_k127_1296007_3 AcrB/AcrD/AcrF family K03296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 331.0
HFD3_k127_1296007_4 DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 316.0
HFD3_k127_1296007_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004169 256.0
HFD3_k127_1296007_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000006119 235.0
HFD3_k127_1296007_7 DinB family - - - 0.000000000000000000000000000000000000000000004272 168.0
HFD3_k127_1296007_8 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000004697 169.0
HFD3_k127_1296007_9 Endonuclease Exonuclease Phosphatase - - - 0.00000000000000000000004341 107.0
HFD3_k127_1306989_0 Protein of unknown function (DUF1223) - - - 0.0000000000000000000000000000000000000000000000000000001125 205.0
HFD3_k127_1306989_1 Cytochrome C biogenesis protein K06196,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000313 203.0
HFD3_k127_1306989_2 peroxiredoxin activity K03386,K03564,K16922 - 1.11.1.15 0.000000000000000000000000000000000000003963 156.0
HFD3_k127_1306989_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000001436 130.0
HFD3_k127_1306989_4 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000002287 110.0
HFD3_k127_1306989_6 Protein of unknown function, DUF255 K06888 - - 0.000000001273 65.0
HFD3_k127_1306989_7 uridine kinase K00876 - 2.7.1.48 0.0005913 44.0
HFD3_k127_1399658_0 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 507.0
HFD3_k127_1399658_1 Sulfatase K01133 - 3.1.6.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 467.0
HFD3_k127_1399658_2 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000005361 140.0
HFD3_k127_140675_0 COG NOG06097 non supervised orthologous group - - - 2.836e-275 879.0
HFD3_k127_140675_1 Belongs to the glycosyl hydrolase 2 family - - - 1.596e-254 822.0
HFD3_k127_140675_10 FCD - - - 0.00000000000000000000000000000000000001661 152.0
HFD3_k127_140675_2 polygalacturonase activity K01184 - 3.2.1.15 9.326e-198 626.0
HFD3_k127_140675_3 Right handed beta helix region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000954 596.0
HFD3_k127_140675_4 Class II Aldolase and Adducin N-terminal domain K00001,K01629 - 1.1.1.1,4.1.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006054 539.0
HFD3_k127_140675_5 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 505.0
HFD3_k127_140675_6 sugar isomerase K01820 - 5.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 490.0
HFD3_k127_140675_7 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 465.0
HFD3_k127_140675_8 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 417.0
HFD3_k127_140675_9 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 320.0
HFD3_k127_1422574_0 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.0000000000000000000000000000001372 126.0
HFD3_k127_1422574_1 Putative auto-transporter adhesin, head GIN domain - - - 0.000000000000000000000000001836 120.0
HFD3_k127_1422574_2 COG0491 Zn-dependent hydrolases, including glyoxylases K01069 - 3.1.2.6 0.000000000000000000000179 100.0
HFD3_k127_1422574_3 Protein of unknown function (DUF445) - - - 0.000000000000000000001751 109.0
HFD3_k127_1460908_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 8.659e-277 860.0
HFD3_k127_1460908_1 PBS lyase HEAT-like repeat - - - 7.873e-213 682.0
HFD3_k127_1460908_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004801 593.0
HFD3_k127_1460908_3 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005793 537.0
HFD3_k127_1460908_4 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 459.0
HFD3_k127_1460908_5 Na dependent nucleoside transporter K03317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007997 363.0
HFD3_k127_1460908_6 DNA alkylation repair - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005403 311.0
HFD3_k127_1460908_7 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000000000000000000000006494 188.0
HFD3_k127_1460908_8 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000000000467 154.0
HFD3_k127_1460908_9 Sporulation and spore germination - - - 0.0000001343 59.0
HFD3_k127_1553132_0 Zinc-binding dehydrogenase - - - 9.388e-294 919.0
HFD3_k127_1553132_1 ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter K01535 - 3.6.3.6 2.278e-293 923.0
HFD3_k127_1553132_10 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 517.0
HFD3_k127_1553132_11 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 473.0
HFD3_k127_1553132_12 PFAM Pyrrolo-quinoline quinone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005254 434.0
HFD3_k127_1553132_13 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 419.0
HFD3_k127_1553132_14 Alginate export - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002996 413.0
HFD3_k127_1553132_15 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000601 373.0
HFD3_k127_1553132_16 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 372.0
HFD3_k127_1553132_17 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006305 351.0
HFD3_k127_1553132_18 Ankyrin repeats (many copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006347 335.0
HFD3_k127_1553132_19 COG3209 Rhs family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 318.0
HFD3_k127_1553132_2 repeat protein - - - 9.729e-280 876.0
HFD3_k127_1553132_20 Beta-lactamase class C and other penicillin binding K01286 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004463 304.0
HFD3_k127_1553132_21 HlyD family secretion protein K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006273 289.0
HFD3_k127_1553132_22 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000491 258.0
HFD3_k127_1553132_23 Integrase core domain K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007304 253.0
HFD3_k127_1553132_24 Domain of unknown function (DUF305) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004464 251.0
HFD3_k127_1553132_25 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000000001052 232.0
HFD3_k127_1553132_26 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000000000000000001317 226.0
HFD3_k127_1553132_27 HAD-hyrolase-like K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000003502 199.0
HFD3_k127_1553132_28 regulatory protein TetR - - - 0.00000000000000000000000000000000000000000000001583 177.0
HFD3_k127_1553132_29 - - - - 0.0000000000000000000000000000000000000000000002612 171.0
HFD3_k127_1553132_3 ABC-type transport system involved in lipoprotein release permease component K02004 - - 5.528e-279 878.0
HFD3_k127_1553132_30 BON domain - - - 0.00000000000000000000000000000000000000000001068 170.0
HFD3_k127_1553132_32 NnrS protein - - - 0.00000000000000000000000000000000000000004761 165.0
HFD3_k127_1553132_33 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000000000000002971 150.0
HFD3_k127_1553132_34 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000004376 146.0
HFD3_k127_1553132_35 Universal stress protein family - - - 0.00000000000000000000000000005308 129.0
HFD3_k127_1553132_37 TIR domain - - - 0.0000000000000000000000000004749 125.0
HFD3_k127_1553132_38 PFAM Uncharacterised BCR, COG1649 - - - 0.00000000000000000000000001502 128.0
HFD3_k127_1553132_39 AMP binding - - - 0.0000000000000000001398 100.0
HFD3_k127_1553132_4 peptide catabolic process - - - 4.921e-229 722.0
HFD3_k127_1553132_40 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000007768 91.0
HFD3_k127_1553132_41 COG1874 Beta-galactosidase K04753,K12567 - 2.7.11.1 0.000000000005125 80.0
HFD3_k127_1553132_42 Universal stress protein family - - - 0.0000000001862 72.0
HFD3_k127_1553132_43 - - - - 0.000000000737 73.0
HFD3_k127_1553132_44 Cupin domain - - - 0.000000001835 61.0
HFD3_k127_1553132_46 Family of unknown function (DUF5335) - - - 0.0000002415 57.0
HFD3_k127_1553132_49 Tetratricopeptide repeat - - - 0.0004549 51.0
HFD3_k127_1553132_5 Di-haem oxidoreductase, putative peroxidase K01201 - 3.2.1.45 3.144e-194 620.0
HFD3_k127_1553132_6 Alpha-L-fucosidase K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 606.0
HFD3_k127_1553132_7 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 595.0
HFD3_k127_1553132_8 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 582.0
HFD3_k127_1553132_9 peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 560.0
HFD3_k127_1554359_0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007373 471.0
HFD3_k127_1554359_1 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005587 443.0
HFD3_k127_1554359_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 298.0
HFD3_k127_1554359_3 AcrB/AcrD/AcrF family K03296 - - 0.0000000000000000000000000000000000000000000000000000000006643 223.0
HFD3_k127_1554359_4 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000004393 168.0
HFD3_k127_1554359_5 Preprotein translocase SecG subunit K03075 - - 0.000000007705 61.0
HFD3_k127_1591201_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 621.0
HFD3_k127_1591201_1 KR domain - - - 0.0000000000000000000000000000000000000000000000000000001719 198.0
HFD3_k127_1591201_2 Polysaccharide lyase family 4, domain III - - - 0.0000000000000000000000000000000000000000000000004907 201.0
HFD3_k127_1591201_3 ABC-type sugar transport system periplasmic component K10439 - - 0.000000000000000000000000000000000000000000000001936 187.0
HFD3_k127_1620416_0 Catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate K00294 - 1.2.1.88 4.576e-210 664.0
HFD3_k127_1620416_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 526.0
HFD3_k127_1620416_10 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 336.0
HFD3_k127_1620416_11 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003849 296.0
HFD3_k127_1620416_12 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000006855 264.0
HFD3_k127_1620416_13 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000242 254.0
HFD3_k127_1620416_14 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000001227 234.0
HFD3_k127_1620416_15 Lysin motif - - - 0.00000000000000000000000000000000000000000000000000000000000000249 229.0
HFD3_k127_1620416_16 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000002447 198.0
HFD3_k127_1620416_17 Alpha/beta hydrolase family K07020 - - 0.000000000000000000000000000000000000000000003168 172.0
HFD3_k127_1620416_18 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000000005422 172.0
HFD3_k127_1620416_19 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000006769 165.0
HFD3_k127_1620416_2 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 505.0
HFD3_k127_1620416_20 S1/P1 Nuclease - - - 0.00000000000000000000000000000000000000114 160.0
HFD3_k127_1620416_21 OsmC-like protein K06889,K07397 - - 0.00000000000000000000000000000000000004293 148.0
HFD3_k127_1620416_22 binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000001052 146.0
HFD3_k127_1620416_23 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000001786 151.0
HFD3_k127_1620416_24 arsenate reductase (glutaredoxin) activity K00537 - 1.20.4.1 0.0000000000000000000000000000004612 124.0
HFD3_k127_1620416_25 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.000000000000000000000000000007239 124.0
HFD3_k127_1620416_26 Regulatory protein - - - 0.000000000000000000000000005366 115.0
HFD3_k127_1620416_27 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000000558 112.0
HFD3_k127_1620416_28 protein with SCP PR1 domains - - - 0.000000000000000000001055 102.0
HFD3_k127_1620416_29 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000844 98.0
HFD3_k127_1620416_3 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 498.0
HFD3_k127_1620416_30 TIGRFAM TonB family K03832 - - 0.0000000000000000001657 100.0
HFD3_k127_1620416_31 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000001334 74.0
HFD3_k127_1620416_32 - - - - 0.0000000007431 61.0
HFD3_k127_1620416_35 serine threonine protein kinase K12132 - 2.7.11.1 0.00001687 55.0
HFD3_k127_1620416_36 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0001469 54.0
HFD3_k127_1620416_4 Cys/Met metabolism PLP-dependent enzyme K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005308 490.0
HFD3_k127_1620416_5 Replicative DNA helicase K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 415.0
HFD3_k127_1620416_6 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 406.0
HFD3_k127_1620416_7 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006925 401.0
HFD3_k127_1620416_8 homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 361.0
HFD3_k127_1620416_9 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 GO:0000287,GO:0003674,GO:0003824,GO:0004799,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009157,GO:0009162,GO:0009165,GO:0009176,GO:0009177,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046073,GO:0046385,GO:0046483,GO:0046872,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 338.0
HFD3_k127_1646527_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 3.492e-203 638.0
HFD3_k127_1646527_1 ROK family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009016 441.0
HFD3_k127_1646527_10 KR domain - - - 0.00000000000000000000000000145 120.0
HFD3_k127_1646527_11 Protein of unknown function (DUF521) K09123 - - 0.000000000000000001596 91.0
HFD3_k127_1646527_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 407.0
HFD3_k127_1646527_3 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004887 402.0
HFD3_k127_1646527_4 Sodium:solute symporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007316 379.0
HFD3_k127_1646527_5 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 364.0
HFD3_k127_1646527_6 Protein of unknown function (DUF1254) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 357.0
HFD3_k127_1646527_7 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 326.0
HFD3_k127_1646527_8 Esterase - - - 0.00000000000000000000000000000000000000000000000007544 189.0
HFD3_k127_1646527_9 Sodium Bile acid symporter family - - - 0.0000000000000000000000000002012 127.0
HFD3_k127_1664289_0 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 6.524e-231 724.0
HFD3_k127_1664289_1 TonB dependent receptor - - - 1.185e-209 698.0
HFD3_k127_1664289_10 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000006992 263.0
HFD3_k127_1664289_11 Protein tyrosine kinase K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000007802 246.0
HFD3_k127_1664289_12 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000001813 204.0
HFD3_k127_1664289_13 transcriptional regulator - - - 0.00000000000000000000000000000000000000000001021 169.0
HFD3_k127_1664289_14 FAD binding domain K21401 - 1.3.99.38 0.000000000000000000000000000000000000001896 162.0
HFD3_k127_1664289_15 RNA recognition motif - - - 0.000000000000000000000000000000000009812 141.0
HFD3_k127_1664289_16 Methyltransferase domain - - - 0.0000000000000000000000000000003397 129.0
HFD3_k127_1664289_17 Protein of unknown function (DUF1697) - - - 0.0000000000000000000000000000003918 130.0
HFD3_k127_1664289_18 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000002089 76.0
HFD3_k127_1664289_19 Tetratricopeptide repeat - - - 0.000000001431 70.0
HFD3_k127_1664289_2 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 490.0
HFD3_k127_1664289_20 oxidoreductase activity - - - 0.00000003384 66.0
HFD3_k127_1664289_3 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 492.0
HFD3_k127_1664289_4 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 467.0
HFD3_k127_1664289_5 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006284 419.0
HFD3_k127_1664289_6 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601,K03797 - 3.1.11.6,3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 346.0
HFD3_k127_1664289_7 ATPases associated with a variety of cellular activities K05847 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 330.0
HFD3_k127_1664289_8 Histidine-specific methyltransferase, SAM-dependent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001187 289.0
HFD3_k127_1664289_9 ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001382 281.0
HFD3_k127_166820_0 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 595.0
HFD3_k127_166820_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 569.0
HFD3_k127_166820_2 KWG Leptospira - - - 0.000000000000000000000000000000000000000000000000000000000000000002843 240.0
HFD3_k127_166820_3 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.000000000000000000000000000000000000002511 148.0
HFD3_k127_166820_4 Protein conserved in bacteria - - - 0.00000000000005947 74.0
HFD3_k127_1669522_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 8.389e-203 648.0
HFD3_k127_1669522_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 548.0
HFD3_k127_1669522_10 Protein of unknown function DUF84 - - - 0.0000000000005399 77.0
HFD3_k127_1669522_11 Tetratricopeptide repeat - - - 0.0000000006687 70.0
HFD3_k127_1669522_12 phosphorelay signal transduction system - - - 0.00000001667 65.0
HFD3_k127_1669522_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 479.0
HFD3_k127_1669522_3 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 460.0
HFD3_k127_1669522_4 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 359.0
HFD3_k127_1669522_5 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001993 255.0
HFD3_k127_1669522_6 pfkB family carbohydrate kinase K18478 - 2.7.1.184 0.00000000000000000000000000000000000000000000000000000000000000001097 235.0
HFD3_k127_1669522_7 thymidine kinase activity K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000154 230.0
HFD3_k127_1669522_9 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000008422 188.0
HFD3_k127_169404_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.265e-219 696.0
HFD3_k127_169404_1 HELICc2 K03722 - 3.6.4.12 1.739e-195 629.0
HFD3_k127_169404_10 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K07083,K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 348.0
HFD3_k127_169404_11 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 343.0
HFD3_k127_169404_12 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009084 330.0
HFD3_k127_169404_13 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 308.0
HFD3_k127_169404_14 Belongs to the 5'-nucleotidase family K01081 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 293.0
HFD3_k127_169404_15 AIR carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001065 283.0
HFD3_k127_169404_16 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007182 276.0
HFD3_k127_169404_17 peptidyl-tyrosine sulfation K03217,K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000152 274.0
HFD3_k127_169404_18 Phosphoribosyl transferase domain K00760,K15780 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8,6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000104 226.0
HFD3_k127_169404_19 DNA ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000002228 221.0
HFD3_k127_169404_2 PFAM Zinc carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 616.0
HFD3_k127_169404_20 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000625 217.0
HFD3_k127_169404_21 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000000000003713 199.0
HFD3_k127_169404_22 Lecithin:cholesterol acyltransferase - - - 0.00000000000000000000000000000000000000000000000003147 197.0
HFD3_k127_169404_23 - - - - 0.0000000000000000000000000000000000000000000000001912 190.0
HFD3_k127_169404_24 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000003982 179.0
HFD3_k127_169404_25 Crp-like helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000001738 181.0
HFD3_k127_169404_26 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000004053 158.0
HFD3_k127_169404_27 galactose-6-phosphate isomerase activity K00761,K01808 - 2.4.2.9,5.3.1.6 0.00000000000000000000000000000000000001202 160.0
HFD3_k127_169404_28 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00000000000000000000000000000000008112 149.0
HFD3_k127_169404_29 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000316 134.0
HFD3_k127_169404_3 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 558.0
HFD3_k127_169404_30 nucleotide catabolic process K01081,K01119,K11751 - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 0.00000000000000000001182 103.0
HFD3_k127_169404_31 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07658 - - 0.000000000000000000989 92.0
HFD3_k127_169404_33 von Willebrand factor, type A - - - 0.0000796 53.0
HFD3_k127_169404_4 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 539.0
HFD3_k127_169404_5 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 462.0
HFD3_k127_169404_6 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000803 467.0
HFD3_k127_169404_7 dna ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 433.0
HFD3_k127_169404_8 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 383.0
HFD3_k127_169404_9 Ribonuclease HII K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 369.0
HFD3_k127_1706180_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.237e-196 637.0
HFD3_k127_1706180_1 class II (D K K01893 - 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 605.0
HFD3_k127_1706180_10 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 GO:0000726,GO:0003674,GO:0003824,GO:0003953,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006464,GO:0006471,GO:0006476,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016787,GO:0016798,GO:0016799,GO:0019213,GO:0019538,GO:0030312,GO:0033554,GO:0033558,GO:0034641,GO:0034979,GO:0035601,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070213,GO:0071214,GO:0071478,GO:0071479,GO:0071704,GO:0071944,GO:0090304,GO:0098732,GO:0104004,GO:0140096,GO:1901360,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000001409 229.0
HFD3_k127_1706180_11 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000000003233 201.0
HFD3_k127_1706180_12 Nucleotidyl transferase K00966,K16881 - 2.7.7.13,5.4.2.8 0.0000000000000000000000000000000000000000000000000005948 196.0
HFD3_k127_1706180_13 phosphotransferase related to Ser Thr protein kinases K07102 - 2.7.1.221 0.00000000000000000000000000000000000003304 156.0
HFD3_k127_1706180_14 PFAM von Willebrand factor type A - - - 0.000000000000000000000000000003289 131.0
HFD3_k127_1706180_2 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 483.0
HFD3_k127_1706180_3 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 392.0
HFD3_k127_1706180_4 D-ala D-ala ligase N-terminus K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 383.0
HFD3_k127_1706180_5 Belongs to the arginase family K01476 GO:0003674,GO:0003824,GO:0004053,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 3.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 327.0
HFD3_k127_1706180_6 Mitochondrial biogenesis AIM24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 294.0
HFD3_k127_1706180_7 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000002711 275.0
HFD3_k127_1706180_8 Hydrolase, TatD family K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007562 263.0
HFD3_k127_1706180_9 PFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000005475 238.0
HFD3_k127_1771998_0 Multicopper oxidase - - - 0.0 1356.0
HFD3_k127_1771998_1 FtsX-like permease family - - - 3.56e-214 709.0
HFD3_k127_1771998_10 Glucose / Sorbosone dehydrogenase K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004145 379.0
HFD3_k127_1771998_11 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 371.0
HFD3_k127_1771998_12 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 366.0
HFD3_k127_1771998_13 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000039 359.0
HFD3_k127_1771998_14 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005274 357.0
HFD3_k127_1771998_15 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 339.0
HFD3_k127_1771998_16 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005463 323.0
HFD3_k127_1771998_17 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007521 316.0
HFD3_k127_1771998_18 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K02003,K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004346 255.0
HFD3_k127_1771998_19 OsmC-like protein K07397 - - 0.0000000000000000000000000000000000000000008244 161.0
HFD3_k127_1771998_2 siderophore transport K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 593.0
HFD3_k127_1771998_20 Lytic transglycosylase catalytic K08309 - - 0.000000000000000000000000001751 127.0
HFD3_k127_1771998_21 - - - - 0.000000000000000000000000007715 122.0
HFD3_k127_1771998_22 - - - - 0.00000000000000000000000009793 112.0
HFD3_k127_1771998_23 IMP dehydrogenase activity - - - 0.00000000000000000000001605 109.0
HFD3_k127_1771998_24 Bacterial DNA-binding protein K03530 - - 0.00000000000000000000002494 102.0
HFD3_k127_1771998_25 - - - - 0.000000000000000000009627 103.0
HFD3_k127_1771998_26 ATPase family associated with various cellular activities (AAA) K10943 - - 0.0000000000000000009509 93.0
HFD3_k127_1771998_27 Cellulase (glycosyl hydrolase family 5) K01179 - 3.2.1.4 0.00000000000000005484 96.0
HFD3_k127_1771998_28 acetyltransferase K06976 - - 0.0000000000000001856 91.0
HFD3_k127_1771998_29 Hypothetical methyltransferase - - - 0.00000000001029 73.0
HFD3_k127_1771998_3 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 561.0
HFD3_k127_1771998_30 Tetratricopeptide repeat K09527 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0030544,GO:0031072,GO:0051084,GO:0051085,GO:0061077 - 0.00000000002712 73.0
HFD3_k127_1771998_31 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000009774 59.0
HFD3_k127_1771998_34 metallopeptidase activity K01387 - 3.4.24.3 0.00008979 56.0
HFD3_k127_1771998_35 - - - - 0.0001137 51.0
HFD3_k127_1771998_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 557.0
HFD3_k127_1771998_5 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004982 501.0
HFD3_k127_1771998_6 COG0635 Coproporphyrinogen III oxidase and related Fe-S - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008793 500.0
HFD3_k127_1771998_7 Sodium hydrogen exchanger - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 430.0
HFD3_k127_1771998_8 COG0644 Dehydrogenases (flavoproteins) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004761 417.0
HFD3_k127_1771998_9 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 384.0
HFD3_k127_1789141_0 - - - - 5.15e-281 894.0
HFD3_k127_1789141_1 Alpha-L-arabinofuranosidase C-terminal domain K01209 - 3.2.1.55 1.516e-246 770.0
HFD3_k127_1789141_10 TAP-like protein - - - 0.00001091 48.0
HFD3_k127_1789141_2 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003957 613.0
HFD3_k127_1789141_3 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004233 250.0
HFD3_k127_1789141_4 helix_turn_helix, arabinose operon control protein K07506 - - 0.000000000000000000000000000000000000000000000000000000000000000000001791 244.0
HFD3_k127_1789141_5 Melibiase K07407 GO:0003674,GO:0003824,GO:0004553,GO:0004557,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0009056,GO:0015925,GO:0016137,GO:0016139,GO:0016787,GO:0016798,GO:0042802,GO:0042803,GO:0046983,GO:0071704,GO:1901135,GO:1901136,GO:1901575,GO:1901657,GO:1901658 3.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000002806 258.0
HFD3_k127_1789141_6 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000000000001284 185.0
HFD3_k127_1789141_7 Alpha galactosidase A K07407 - 3.2.1.22 0.00000000000000000001775 108.0
HFD3_k127_1789141_8 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000003855 59.0
HFD3_k127_1789141_9 hydrolase activity, acting on ester bonds - - - 0.0000001027 58.0
HFD3_k127_1801737_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 2.83e-223 709.0
HFD3_k127_1801737_1 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000003534 205.0
HFD3_k127_1801737_2 Ribosomal protein L35 K02916 - - 0.000000000000000004059 85.0
HFD3_k127_1812093_0 cell shape determining protein MreB K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000355 507.0
HFD3_k127_1812093_1 N,N-dimethylaniline monooxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 459.0
HFD3_k127_1812093_10 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.0000000000000000000000000000000000001083 156.0
HFD3_k127_1812093_11 PFAM nuclease (SNase domain protein) - - - 0.000000000000000002123 91.0
HFD3_k127_1812093_13 Roadblock/LC7 domain - - - 0.00000000000006359 76.0
HFD3_k127_1812093_14 extracellular matrix structural constituent K02035 - - 0.00000000005054 76.0
HFD3_k127_1812093_15 TrwC relaxase - - - 0.0000000000824 64.0
HFD3_k127_1812093_17 PFAM Pilus assembly protein PilO K02664 - - 0.0000004293 59.0
HFD3_k127_1812093_18 Helix-turn-helix XRE-family like proteins - - - 0.00009981 49.0
HFD3_k127_1812093_19 PFAM Fimbrial assembly family protein K02663 - - 0.000456 50.0
HFD3_k127_1812093_2 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 319.0
HFD3_k127_1812093_3 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 318.0
HFD3_k127_1812093_4 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007937 314.0
HFD3_k127_1812093_5 maltose O-acetyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000009772 243.0
HFD3_k127_1812093_6 Alpha-tubulin suppressor and related RCC1 domain-containing proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000006627 262.0
HFD3_k127_1812093_7 Secretin and TonB N terminus short domain K02666 - - 0.00000000000000000000000000000000000000000000000000000000002179 230.0
HFD3_k127_1812093_8 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000001261 188.0
HFD3_k127_1812093_9 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000006826 185.0
HFD3_k127_1853328_0 Belongs to the glycosyl hydrolase 31 family K01811 - 3.2.1.177 0.0 1134.0
HFD3_k127_1853328_1 Fibronectin type III-like domain K05349 - 3.2.1.21 0.0 1034.0
HFD3_k127_1853328_10 PFAM Glycoside hydrolase family 2 K01192 - 3.2.1.25 7.012e-252 803.0
HFD3_k127_1853328_11 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01706 - 4.2.1.40 1.898e-225 703.0
HFD3_k127_1853328_12 Alpha-L-arabinofuranosidase K01209 - 3.2.1.55 6.802e-220 693.0
HFD3_k127_1853328_13 ASPIC and UnbV - - - 3.905e-219 692.0
HFD3_k127_1853328_14 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667 - 4.1.99.1 4.831e-219 691.0
HFD3_k127_1853328_15 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 4.824e-199 625.0
HFD3_k127_1853328_16 Dienelactone hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 614.0
HFD3_k127_1853328_17 beta-galactosidase activity K05970 - 3.1.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005933 602.0
HFD3_k127_1853328_18 xylose isomerase activity K01805 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575 5.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 571.0
HFD3_k127_1853328_19 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 564.0
HFD3_k127_1853328_2 Belongs to the glycosyl hydrolase 2 family K01190 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0004565,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0015925,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899 3.2.1.23 2.405e-312 975.0
HFD3_k127_1853328_20 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760 - 2.5.1.48,4.4.1.1,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 522.0
HFD3_k127_1853328_21 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 463.0
HFD3_k127_1853328_22 glucuronate isomerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 460.0
HFD3_k127_1853328_23 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000864 473.0
HFD3_k127_1853328_24 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 409.0
HFD3_k127_1853328_25 PFAM ROK family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006629 397.0
HFD3_k127_1853328_26 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 380.0
HFD3_k127_1853328_27 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 370.0
HFD3_k127_1853328_28 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 368.0
HFD3_k127_1853328_29 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 354.0
HFD3_k127_1853328_3 Glycosyl hydrolase family 65, N-terminal domain K15923 - 3.2.1.51 6.274e-296 929.0
HFD3_k127_1853328_30 PFAM Glycosyl hydrolase family 10 K01181 - 3.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 364.0
HFD3_k127_1853328_31 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 319.0
HFD3_k127_1853328_32 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 312.0
HFD3_k127_1853328_33 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 309.0
HFD3_k127_1853328_34 alpha/beta hydrolase fold K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 297.0
HFD3_k127_1853328_35 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 298.0
HFD3_k127_1853328_36 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 293.0
HFD3_k127_1853328_37 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002482 278.0
HFD3_k127_1853328_38 succinylglutamate desuccinylase activity K05526 - 3.5.1.96 0.0000000000000000000000000000000000000000000000000000000000000000000000000009453 270.0
HFD3_k127_1853328_39 family 16 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009041 263.0
HFD3_k127_1853328_4 MacB-like periplasmic core domain - - - 1.353e-293 923.0
HFD3_k127_1853328_41 ROK family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000142 256.0
HFD3_k127_1853328_42 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001441 253.0
HFD3_k127_1853328_43 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007358 248.0
HFD3_k127_1853328_44 Ammonium Transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008963 240.0
HFD3_k127_1853328_45 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.0000000000000000000000000000000000000000000000000000000000000000005536 238.0
HFD3_k127_1853328_46 NAD dependent epimerase/dehydratase family K07535 - - 0.0000000000000000000000000000000000000000000000000000000000000001326 229.0
HFD3_k127_1853328_47 NIPSNAP - - - 0.0000000000000000000000000000000000000000000000000000000321 197.0
HFD3_k127_1853328_48 - - - - 0.000000000000000000000000000000000000000000000000000001767 201.0
HFD3_k127_1853328_49 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000003427 192.0
HFD3_k127_1853328_5 Fibronectin type III-like domain K05349 - 3.2.1.21 5.578e-292 912.0
HFD3_k127_1853328_50 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000003198 185.0
HFD3_k127_1853328_51 - - - - 0.00000000000000000000000000000000000000000000004732 176.0
HFD3_k127_1853328_52 MTH538 TIR-like domain (DUF1863) - - - 0.0000000000000000000000000000000000000000001477 183.0
HFD3_k127_1853328_53 Domain of unknown function (DUF4386) - - - 0.00000000000000000000000000000000000000002459 161.0
HFD3_k127_1853328_54 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000004458 156.0
HFD3_k127_1853328_55 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000002482 149.0
HFD3_k127_1853328_56 O-methyltransferase activity - - - 0.0000000000000000000000000000000000001618 151.0
HFD3_k127_1853328_57 META domain K03929 - - 0.000000000000000000000000000000002188 134.0
HFD3_k127_1853328_58 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00000000000000000000000000003342 136.0
HFD3_k127_1853328_59 Belongs to the glycosyl hydrolase 26 family - - - 0.000000000000001142 85.0
HFD3_k127_1853328_6 Carboxypeptidase regulatory-like domain - - - 4.277e-282 908.0
HFD3_k127_1853328_60 WD40 repeat-like protein - - - 0.00000000000005884 83.0
HFD3_k127_1853328_61 TPR repeat - - - 0.00000000004603 74.0
HFD3_k127_1853328_62 Repeats in polycystic kidney disease 1 (PKD1) and other proteins K01179 - 3.2.1.4 0.000000001085 70.0
HFD3_k127_1853328_63 guanyl-nucleotide exchange factor activity K01179,K03929,K09612,K12287,K19701,K19702 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005623,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.2.1.4,3.4.11.10,3.4.11.24,3.4.11.6 0.00000004421 66.0
HFD3_k127_1853328_64 PLD-like domain - - - 0.0005532 53.0
HFD3_k127_1853328_7 Two component regulator propeller - - - 5.002e-280 891.0
HFD3_k127_1853328_8 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 2.321e-264 836.0
HFD3_k127_1853328_9 Belongs to the glycosyl hydrolase 67 family K01235 - 3.2.1.139 6.207e-260 820.0
HFD3_k127_1860060_0 cellulose binding - - - 0.0 1562.0
HFD3_k127_1860060_1 Tricorn protease C1 domain K08676 - - 0.0 1335.0
HFD3_k127_1860060_10 PFAM Beta-eliminating lyase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009617 469.0
HFD3_k127_1860060_11 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009425 442.0
HFD3_k127_1860060_12 Ring hydroxylating alpha subunit (catalytic domain) K00479 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 438.0
HFD3_k127_1860060_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004463 392.0
HFD3_k127_1860060_14 Belongs to the FGGY kinase family K00851 - 2.7.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009448 388.0
HFD3_k127_1860060_15 amino acid K03294,K20265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 356.0
HFD3_k127_1860060_16 PhoQ Sensor K07640 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 356.0
HFD3_k127_1860060_17 Transcriptional regulatory protein, C terminal K07662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 311.0
HFD3_k127_1860060_18 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 315.0
HFD3_k127_1860060_19 Flagellar Assembly Protein A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003983 277.0
HFD3_k127_1860060_2 Flavin containing amine oxidoreductase - - - 9.741e-292 902.0
HFD3_k127_1860060_20 T4-like virus tail tube protein gp19 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005751 271.0
HFD3_k127_1860060_21 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004533 257.0
HFD3_k127_1860060_22 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000002049 225.0
HFD3_k127_1860060_23 T4-like virus tail tube protein gp19 - - - 0.000000000000000000000000000000000000000000000000000000000002017 212.0
HFD3_k127_1860060_24 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000001169 218.0
HFD3_k127_1860060_25 - - - - 0.00000000000000000000000000000000000000000000000000000003547 208.0
HFD3_k127_1860060_26 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000001058 211.0
HFD3_k127_1860060_27 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000004794 188.0
HFD3_k127_1860060_28 Protein of unknown function (DUF4255) - - - 0.000000000000000000000000000000000000000000000000001574 188.0
HFD3_k127_1860060_29 acetyltransferase - - - 0.00000000000000000000000000000000000000000005564 164.0
HFD3_k127_1860060_3 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 2.234e-275 861.0
HFD3_k127_1860060_30 PFAM Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000000001125 145.0
HFD3_k127_1860060_31 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.00000000000000000000000000000000703 136.0
HFD3_k127_1860060_32 Gram-negative bacterial TonB protein C-terminal - - - 0.00000000006317 70.0
HFD3_k127_1860060_34 - - - - 0.00002792 49.0
HFD3_k127_1860060_4 tail sheath protein K06907 - - 8.058e-249 781.0
HFD3_k127_1860060_5 Carboxypeptidase regulatory-like domain - - - 7.292e-248 800.0
HFD3_k127_1860060_6 Phage tail sheath protein subtilisin-like domain - - - 1.874e-204 670.0
HFD3_k127_1860060_7 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008294 570.0
HFD3_k127_1860060_8 TIGRFAM phytoene desaturase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 546.0
HFD3_k127_1860060_9 peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008918 527.0
HFD3_k127_1873483_0 Carboxypeptidase regulatory-like domain - - - 0.0 1181.0
HFD3_k127_1873483_1 - - - - 0.0 1101.0
HFD3_k127_1873483_2 Beta-L-arabinofuranosidase, GH127 K09955 - - 1.247e-285 897.0
HFD3_k127_1873483_3 Belongs to the mandelate racemase muconate lactonizing enzyme family K01706 - 4.2.1.40 1.107e-225 704.0
HFD3_k127_1873483_4 Glycogen debranching enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 578.0
HFD3_k127_1873483_5 TIGRFAM galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 469.0
HFD3_k127_1873483_6 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 381.0
HFD3_k127_1873483_7 Belongs to the glycosyl hydrolase 31 family K01187,K01811 - 3.2.1.177,3.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000643 308.0
HFD3_k127_1873483_8 - - - - 0.00000000000000000000000000003253 121.0
HFD3_k127_1907369_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0 1439.0
HFD3_k127_1907369_1 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 398.0
HFD3_k127_1907369_2 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004939 289.0
HFD3_k127_1919731_0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0 1351.0
HFD3_k127_1919731_1 peroxiredoxin activity - - - 2.638e-302 936.0
HFD3_k127_1919731_10 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 610.0
HFD3_k127_1919731_11 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 553.0
HFD3_k127_1919731_12 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 584.0
HFD3_k127_1919731_13 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 453.0
HFD3_k127_1919731_14 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 432.0
HFD3_k127_1919731_15 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006627 376.0
HFD3_k127_1919731_16 COGs COG4299 conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 373.0
HFD3_k127_1919731_17 nuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 368.0
HFD3_k127_1919731_18 electron transport chain K00347,K03614,K21163 - 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 367.0
HFD3_k127_1919731_19 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006433 370.0
HFD3_k127_1919731_2 PFAM Glycosyl hydrolase family 3 C terminal domain - - - 3.82e-261 826.0
HFD3_k127_1919731_20 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 332.0
HFD3_k127_1919731_21 ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 334.0
HFD3_k127_1919731_22 beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 315.0
HFD3_k127_1919731_23 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001299 265.0
HFD3_k127_1919731_24 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000001669 265.0
HFD3_k127_1919731_25 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000000000000001008 230.0
HFD3_k127_1919731_26 Sigma-70 region 2 - - - 0.0000000000000000000000000000000000000000000000000000000000001702 243.0
HFD3_k127_1919731_27 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000003606 213.0
HFD3_k127_1919731_28 ROK family - - - 0.0000000000000000000000000000000000000000000000000000000001066 219.0
HFD3_k127_1919731_29 PFAM 3-carboxy-cis,cis-muconate lactonizing enzyme K07404 - 3.1.1.31 0.0000000000000000000000000000000000000000000000000000000004311 205.0
HFD3_k127_1919731_3 Carboxypeptidase regulatory-like domain - - - 4.921e-247 799.0
HFD3_k127_1919731_30 YCII-related domain - - - 0.00000000000000000000000000000000000000000000000000009232 188.0
HFD3_k127_1919731_31 3-demethylubiquinone-9 3-methyltransferase K04750 - - 0.00000000000000000000000000000000000000000000000002571 187.0
HFD3_k127_1919731_32 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000001173 152.0
HFD3_k127_1919731_33 Glyoxalase-like domain K04750 - - 0.0000000000000000000000000000000008932 132.0
HFD3_k127_1919731_34 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000002217 121.0
HFD3_k127_1919731_35 glyoxalase III activity - - - 0.0000000000000000000000000009785 116.0
HFD3_k127_1919731_36 transmembrane transporter activity - - - 0.0000000000000000000000002516 106.0
HFD3_k127_1919731_37 Transglutaminase-like superfamily - - - 0.0000000000000000009045 95.0
HFD3_k127_1919731_39 sequence-specific DNA binding - - - 0.00000000000006104 82.0
HFD3_k127_1919731_4 ASPIC and UnbV - - - 3.094e-245 770.0
HFD3_k127_1919731_40 Redoxin - - - 0.0000000000001147 75.0
HFD3_k127_1919731_41 FAD binding domain - - - 0.0000000000002792 72.0
HFD3_k127_1919731_42 - - - - 0.00000000001777 74.0
HFD3_k127_1919731_43 sequence-specific DNA binding - - - 0.00000000002139 72.0
HFD3_k127_1919731_45 kinesin light chain - - - 0.0000001327 64.0
HFD3_k127_1919731_46 transcriptional regulator - - - 0.00001841 52.0
HFD3_k127_1919731_47 Cytochrome c554 and c-prime - - - 0.0005888 46.0
HFD3_k127_1919731_48 IrrE N-terminal-like domain - - - 0.00062 50.0
HFD3_k127_1919731_49 alkyl hydroperoxide reductase - - - 0.0009716 48.0
HFD3_k127_1919731_5 Putative carbohydrate binding domain K12373 - 3.2.1.52 2.687e-238 755.0
HFD3_k127_1919731_6 ASPIC and UnbV - - - 1.927e-222 701.0
HFD3_k127_1919731_7 MatE - - - 8.44e-218 684.0
HFD3_k127_1919731_8 ASPIC and UnbV - - - 1.881e-200 640.0
HFD3_k127_1919731_9 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 623.0
HFD3_k127_1946438_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 522.0
HFD3_k127_1946438_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007469 391.0
HFD3_k127_1946438_10 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000005946 183.0
HFD3_k127_1946438_11 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000002 184.0
HFD3_k127_1946438_12 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000002008 181.0
HFD3_k127_1946438_13 Binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000004301 166.0
HFD3_k127_1946438_14 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000000006243 156.0
HFD3_k127_1946438_15 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000006068 134.0
HFD3_k127_1946438_16 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000001809 114.0
HFD3_k127_1946438_17 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000006229 113.0
HFD3_k127_1946438_18 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000006383 107.0
HFD3_k127_1946438_19 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000002622 102.0
HFD3_k127_1946438_2 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 309.0
HFD3_k127_1946438_20 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000002531 93.0
HFD3_k127_1946438_21 Ribosomal protein L30 K02907 - - 0.0000000000000002777 80.0
HFD3_k127_1946438_22 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000002452 51.0
HFD3_k127_1946438_3 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004917 280.0
HFD3_k127_1946438_4 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000007427 240.0
HFD3_k127_1946438_5 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000000000001761 228.0
HFD3_k127_1946438_6 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000002796 218.0
HFD3_k127_1946438_7 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.0000000000000000000000000000000000000000000000000000000000008301 218.0
HFD3_k127_1946438_8 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000003224 196.0
HFD3_k127_1946438_9 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000000001391 187.0
HFD3_k127_19684_0 Dipeptidyl peptidase IV (DPP IV) K01278 - 3.4.14.5 1.651e-290 910.0
HFD3_k127_19684_1 X-Pro dipeptidyl-peptidase (S15 family) - - - 8.182e-254 797.0
HFD3_k127_19684_10 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 501.0
HFD3_k127_19684_11 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 486.0
HFD3_k127_19684_12 Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 484.0
HFD3_k127_19684_13 His Kinase A (phosphoacceptor) domain K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006189 486.0
HFD3_k127_19684_14 RmlD substrate binding domain K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 428.0
HFD3_k127_19684_15 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 431.0
HFD3_k127_19684_16 Wzt C-terminal domain K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005038 404.0
HFD3_k127_19684_17 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 379.0
HFD3_k127_19684_18 PFAM Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 403.0
HFD3_k127_19684_19 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 365.0
HFD3_k127_19684_2 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 1.223e-234 742.0
HFD3_k127_19684_20 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 351.0
HFD3_k127_19684_21 PFAM GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 354.0
HFD3_k127_19684_22 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005629 321.0
HFD3_k127_19684_23 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 337.0
HFD3_k127_19684_24 pfam abc K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 310.0
HFD3_k127_19684_25 TOBE domain K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 303.0
HFD3_k127_19684_26 Deoxyhypusine synthase K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000507 286.0
HFD3_k127_19684_27 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001354 288.0
HFD3_k127_19684_28 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001454 261.0
HFD3_k127_19684_29 6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000001044 251.0
HFD3_k127_19684_3 acyl-CoA dehydrogenase activity K09456 - - 2.938e-229 722.0
HFD3_k127_19684_30 PFAM short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000038 252.0
HFD3_k127_19684_31 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009247 254.0
HFD3_k127_19684_32 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000625 248.0
HFD3_k127_19684_33 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000004125 228.0
HFD3_k127_19684_34 methyltransferase K18827 - 2.1.1.294,2.7.1.181 0.000000000000000000000000000000000000000000000000000000000000005827 235.0
HFD3_k127_19684_35 ABC-2 type transporter K01992,K09690,K09691,K09692 - - 0.0000000000000000000000000000000000000000000000000000000000064 216.0
HFD3_k127_19684_36 Phosphomethylpyrimidine kinase K00868,K00941,K14153 - 2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000003106 211.0
HFD3_k127_19684_37 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000001868 222.0
HFD3_k127_19684_38 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000001671 196.0
HFD3_k127_19684_39 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000002132 194.0
HFD3_k127_19684_4 benzoyl-CoA oxygenase K15512 - 1.14.13.208 1.922e-213 671.0
HFD3_k127_19684_40 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000001173 181.0
HFD3_k127_19684_41 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000002491 178.0
HFD3_k127_19684_42 Enoyl-CoA hydratase/isomerase K15513 - 4.1.2.44 0.0000000000000000000000000000000000000000000008379 168.0
HFD3_k127_19684_43 BON domain - - - 0.000000000000000000000000000000000000000000004678 171.0
HFD3_k127_19684_44 HAD-superfamily hydrolase, subfamily IIB - - - 0.000000000000000000000000000000000000000005806 166.0
HFD3_k127_19684_45 - - - - 0.0000000000000000000000000000000000000008274 170.0
HFD3_k127_19684_46 Bacterial regulatory proteins, tetR family K09017 - - 0.0000000000000000000000000000000000000465 151.0
HFD3_k127_19684_47 CHRD domain - - - 0.0000000000000000000000000000000000001252 149.0
HFD3_k127_19684_48 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000001723 141.0
HFD3_k127_19684_49 Tetratricopeptide repeat - - - 0.000000000000000000000000000000007003 143.0
HFD3_k127_19684_5 glutamine synthetase K01915 GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319 6.3.1.2 4.19e-207 653.0
HFD3_k127_19684_50 acetylesterase activity - - - 0.000000000000000000000000000001996 136.0
HFD3_k127_19684_51 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000108 128.0
HFD3_k127_19684_52 diguanylate cyclase - - - 0.00000000000000000000001997 114.0
HFD3_k127_19684_53 protein import - - - 0.0000000000000004813 93.0
HFD3_k127_19684_54 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000127 63.0
HFD3_k127_19684_55 to Saccharomyces cerevisiae HOS4 (YIL112W) K06867 GO:0000118,GO:0000151,GO:0000228,GO:0000785,GO:0000790,GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0006325,GO:0006464,GO:0006476,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010564,GO:0010639,GO:0010948,GO:0016043,GO:0016567,GO:0016569,GO:0016570,GO:0016575,GO:0016740,GO:0019538,GO:0019787,GO:0019899,GO:0031625,GO:0031974,GO:0031981,GO:0032446,GO:0032991,GO:0033043,GO:0034967,GO:0035601,GO:0036211,GO:0040020,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044389,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044451,GO:0044454,GO:0044464,GO:0045786,GO:0045835,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051276,GO:0051445,GO:0051447,GO:0051726,GO:0051783,GO:0051784,GO:0065007,GO:0070013,GO:0070647,GO:0071704,GO:0071840,GO:0098732,GO:0140096,GO:1901564,GO:1902494,GO:1990234,GO:2000241,GO:2000242 - 0.0000001468 63.0
HFD3_k127_19684_56 -O-antigen - - - 0.000004541 59.0
HFD3_k127_19684_58 Protein of unknown function (DUF721) - - - 0.00001443 53.0
HFD3_k127_19684_59 COG2931 RTX toxins and related Ca2 -binding - - - 0.0001616 55.0
HFD3_k127_19684_6 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 2.773e-197 629.0
HFD3_k127_19684_60 pyrroloquinoline quinone binding - - - 0.0008466 53.0
HFD3_k127_19684_7 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009868 541.0
HFD3_k127_19684_8 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009269 508.0
HFD3_k127_19684_9 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 511.0
HFD3_k127_1971627_0 ABC transporter, transmembrane K18889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 570.0
HFD3_k127_1971627_1 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 447.0
HFD3_k127_1971627_2 (ABC) transporter K06147,K18890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 427.0
HFD3_k127_1971627_3 Ribonuclease, Rne Rng family K08301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 287.0
HFD3_k127_1971627_4 Putative cyclase K07130 - 3.5.1.9 0.00000000000000000000000000000000000000000000000000000005937 204.0
HFD3_k127_1971627_5 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000000000000002984 188.0
HFD3_k127_1971627_6 Belongs to the UPF0145 family - - - 0.000000000000000000000000000000000000000000007087 166.0
HFD3_k127_1971627_7 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567,K07443 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 2.1.1.63 0.0000000000000000000001473 102.0
HFD3_k127_1971627_8 Thioesterase superfamily - - - 0.000000000000002927 80.0
HFD3_k127_1984490_0 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 404.0
HFD3_k127_1984490_1 Peptidase M61 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 331.0
HFD3_k127_1984490_2 Related to alanyl-tRNA synthetase HxxxH domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004626 293.0
HFD3_k127_1984490_3 Diacylglycerol kinase catalytic domain (presumed) - - - 0.0000000000000000000000000000000000000000000000000003157 195.0
HFD3_k127_1984490_4 Phage integrase family - - - 0.0000000000000000000000000004672 119.0
HFD3_k127_1984490_5 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000007702 108.0
HFD3_k127_1990926_0 Carboxypeptidase regulatory-like domain - - - 8.825e-269 855.0
HFD3_k127_1990926_1 SCO1/SenC K07152 - - 0.000000000000000000000000000000000002766 145.0
HFD3_k127_1990926_2 Bilirubin oxidase - - - 0.000000000000000000000000000009509 126.0
HFD3_k127_1990926_3 BNR repeat-like domain - - - 0.00000001825 62.0
HFD3_k127_2047155_0 xanthine dehydrogenase activity K04108 - 1.3.7.9 2.082e-311 974.0
HFD3_k127_2047155_1 iron-nicotianamine transmembrane transporter activity - - - 2.353e-285 900.0
HFD3_k127_2047155_10 Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 496.0
HFD3_k127_2047155_11 Aminotransferase class-V K01556 - 3.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007413 460.0
HFD3_k127_2047155_12 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 415.0
HFD3_k127_2047155_13 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 394.0
HFD3_k127_2047155_14 Fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005269 373.0
HFD3_k127_2047155_15 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 366.0
HFD3_k127_2047155_16 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 364.0
HFD3_k127_2047155_17 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002529 355.0
HFD3_k127_2047155_18 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 354.0
HFD3_k127_2047155_19 ABC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 356.0
HFD3_k127_2047155_2 Zinc carboxypeptidase - - - 4.426e-222 716.0
HFD3_k127_2047155_20 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005221 327.0
HFD3_k127_2047155_21 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 321.0
HFD3_k127_2047155_22 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 318.0
HFD3_k127_2047155_23 PFAM Enoyl-CoA hydratase isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 295.0
HFD3_k127_2047155_24 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001008 285.0
HFD3_k127_2047155_25 Protein containing tetrapyrrole methyltransferase domain and MazG-like K02428,K02499 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000001177 259.0
HFD3_k127_2047155_26 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000000000000000000155 250.0
HFD3_k127_2047155_27 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000583 226.0
HFD3_k127_2047155_28 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000003666 232.0
HFD3_k127_2047155_29 pyridine nucleotide-disulfide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000001426 224.0
HFD3_k127_2047155_3 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.065e-198 635.0
HFD3_k127_2047155_30 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000004174 214.0
HFD3_k127_2047155_31 Protein of unknown function (DUF1572) - - - 0.000000000000000000000000000000000000000000000000000000000004532 211.0
HFD3_k127_2047155_32 Tryptophan 2,3-dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000002323 210.0
HFD3_k127_2047155_33 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000001203 198.0
HFD3_k127_2047155_34 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000008362 182.0
HFD3_k127_2047155_35 TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.0000000000000000000000000000000000001322 151.0
HFD3_k127_2047155_36 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000003631 141.0
HFD3_k127_2047155_37 YHS domain K06966 - 3.2.2.10 0.000000000000000000000000000000000001142 145.0
HFD3_k127_2047155_38 CHRD domain - - - 0.000000000000000000000000000000000008741 141.0
HFD3_k127_2047155_39 translation initiation inhibitor, yjgF family - - - 0.00000000000000000000000000000000001304 139.0
HFD3_k127_2047155_4 NADH oxidase - - - 6.74e-198 627.0
HFD3_k127_2047155_40 PFAM HD domain - - - 0.0000000000000000000000000000002149 133.0
HFD3_k127_2047155_41 transcriptional regulator K03655 - 3.6.4.12 0.0000000000000000000000000000002349 138.0
HFD3_k127_2047155_42 NAD+ binding - - - 0.0000000000000000000000000000003821 142.0
HFD3_k127_2047155_43 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000004911 125.0
HFD3_k127_2047155_44 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000000000000000000004451 120.0
HFD3_k127_2047155_45 Carbohydrate family 9 binding domain-like - - - 0.00000000000000000000000003907 115.0
HFD3_k127_2047155_46 Mov34 MPN PAD-1 family K21140 - 3.13.1.6 0.0000000000000000000000005479 109.0
HFD3_k127_2047155_47 - - - - 0.000000000000000000000008865 102.0
HFD3_k127_2047155_48 PFAM response regulator receiver K02483,K07658,K07668 - - 0.000000000000000000004935 109.0
HFD3_k127_2047155_49 - - - - 0.00000000000002946 87.0
HFD3_k127_2047155_5 cell adhesion involved in biofilm formation K13735,K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 638.0
HFD3_k127_2047155_50 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000001483 71.0
HFD3_k127_2047155_51 Domain of unknown function (DUF1844) - - - 0.000000000001619 75.0
HFD3_k127_2047155_52 Thioredoxin-like - - - 0.0000000001068 69.0
HFD3_k127_2047155_53 - - - - 0.000000009407 68.0
HFD3_k127_2047155_54 membrane - - - 0.0001334 52.0
HFD3_k127_2047155_55 Protein conserved in bacteria - - - 0.0004784 51.0
HFD3_k127_2047155_6 SPFH domain / Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 571.0
HFD3_k127_2047155_7 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K04105,K04110 - 6.2.1.25,6.2.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 525.0
HFD3_k127_2047155_8 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K00375 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 519.0
HFD3_k127_2047155_9 40-residue YVTN family beta-propeller repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 516.0
HFD3_k127_2048567_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298,K15408 - 1.10.3.10,1.9.3.1 1.044e-270 848.0
HFD3_k127_2048567_1 Pfam:KaiC K08482 - - 5.702e-223 707.0
HFD3_k127_2048567_10 PFAM PRC-barrel domain - - - 0.000000000000000000000000004718 115.0
HFD3_k127_2048567_11 - - - - 0.000000000000000000000008458 104.0
HFD3_k127_2048567_2 metal ion transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 546.0
HFD3_k127_2048567_3 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006713 398.0
HFD3_k127_2048567_4 cytochrome c oxidase K02351 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008788 349.0
HFD3_k127_2048567_5 PQQ-dependent catabolism-associated beta-propeller protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002547 288.0
HFD3_k127_2048567_6 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000003562 162.0
HFD3_k127_2048567_7 KaiB K08481 - - 0.0000000000000000000000000000000000000002719 152.0
HFD3_k127_2048567_8 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298,K15408 - 1.10.3.10,1.9.3.1 0.000000000000000000000000000000000002207 145.0
HFD3_k127_2048567_9 KaiB K08481 - - 0.00000000000000000000000000000004779 129.0
HFD3_k127_209129_0 PFAM ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005974 454.0
HFD3_k127_209129_1 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 440.0
HFD3_k127_209129_2 PFAM beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 396.0
HFD3_k127_209129_3 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007756 344.0
HFD3_k127_209129_4 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 332.0
HFD3_k127_209129_5 Putative peptidoglycan binding domain - - - 0.00000000000000000000000000000003447 135.0
HFD3_k127_209129_6 - - - - 0.000000000000000000000316 104.0
HFD3_k127_209129_7 - - - - 0.000000000001109 71.0
HFD3_k127_2142598_0 Non-ribosomal peptide synthetase modules and related - - - 5.28e-321 1028.0
HFD3_k127_2142598_1 TIGRFAM amino acid adenylation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 542.0
HFD3_k127_2142598_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 393.0
HFD3_k127_2142598_3 Amino acid adenylation enzyme thioester reductase family protein - - - 0.00004046 47.0
HFD3_k127_2177543_0 surface antigen - - - 0.000000000000000000000000000000000000000000000000671 186.0
HFD3_k127_2177543_1 cheY-homologous receiver domain K11443 - - 0.000000000000000000000000002273 115.0
HFD3_k127_2177543_2 domain protein K14194 - - 0.000000000000000000002248 109.0
HFD3_k127_2177543_3 cAMP biosynthetic process - - - 0.0000001382 55.0
HFD3_k127_2177543_4 TIR domain - - - 0.0002714 54.0
HFD3_k127_2177543_5 Carboxypeptidase regulatory-like domain - - - 0.000514 53.0
HFD3_k127_2178985_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0 1035.0
HFD3_k127_2178985_1 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 4.435e-270 841.0
HFD3_k127_2178985_10 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000004026 194.0
HFD3_k127_2178985_11 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000006821 187.0
HFD3_k127_2178985_12 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000001029 180.0
HFD3_k127_2178985_13 ACT domain K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000009693 163.0
HFD3_k127_2178985_14 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000002276 142.0
HFD3_k127_2178985_15 PQQ enzyme repeat - - - 0.00000000000000000000000798 115.0
HFD3_k127_2178985_16 Protein of unknown function (DUF465) - - - 0.00000606 50.0
HFD3_k127_2178985_2 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 8.621e-202 640.0
HFD3_k127_2178985_3 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 2.963e-198 634.0
HFD3_k127_2178985_4 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 473.0
HFD3_k127_2178985_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007546 350.0
HFD3_k127_2178985_6 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 358.0
HFD3_k127_2178985_7 Cobyrinic acid ac-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003555 283.0
HFD3_k127_2178985_8 Transcriptional regulator, LysR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004904 251.0
HFD3_k127_2178985_9 chromosome segregation K03497 - - 0.000000000000000000000000000000000000000000000000000000000004655 217.0
HFD3_k127_2197049_0 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 399.0
HFD3_k127_2197049_1 Peptidase M16 inactive domain K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 317.0
HFD3_k127_2197049_2 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000000000000000000003347 220.0
HFD3_k127_2197049_3 Serine threonine protein K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000002939 216.0
HFD3_k127_2197049_4 Belongs to the ompA family - - - 0.00002951 55.0
HFD3_k127_2206083_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 1.183e-285 909.0
HFD3_k127_2206083_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 589.0
HFD3_k127_2206083_10 TIR domain - - - 0.00000000000000000000000000000000000002728 152.0
HFD3_k127_2206083_11 protein serine/threonine phosphatase activity - - - 0.0000000000000000004601 93.0
HFD3_k127_2206083_2 COG3621 Patatin K06900 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 395.0
HFD3_k127_2206083_3 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007418 376.0
HFD3_k127_2206083_4 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 297.0
HFD3_k127_2206083_5 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000395 296.0
HFD3_k127_2206083_6 YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007005 271.0
HFD3_k127_2206083_7 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity K16038 GO:0002682,GO:0002684,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0030312,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136 - 0.00000000000000000000000000000000000000000000000000000000002934 215.0
HFD3_k127_2206083_8 DinB family - - - 0.0000000000000000000000000000000000000000000000000000102 196.0
HFD3_k127_2206083_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000275 169.0
HFD3_k127_224391_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1400.0
HFD3_k127_224391_1 4Fe-4S dicluster domain K07307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 328.0
HFD3_k127_224391_2 formate dehydrogenase K00127,K08350 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009326,GO:0009987,GO:0015942,GO:0015944,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0020037,GO:0022900,GO:0031224,GO:0031226,GO:0032787,GO:0032991,GO:0033554,GO:0036397,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0051716,GO:0052738,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.0000000000000000000000000000000000000000000003596 175.0
HFD3_k127_2249582_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.716e-276 861.0
HFD3_k127_2249582_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 6.993e-259 813.0
HFD3_k127_2249582_10 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000000000000000000007909 216.0
HFD3_k127_2249582_11 Transporter associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000001751 229.0
HFD3_k127_2249582_12 - - - - 0.00000000000000000000000000000000000000000000000004254 194.0
HFD3_k127_2249582_13 PFAM Roadblock LC7 family protein - - - 0.0000000000000000000000000000000000000000000008681 171.0
HFD3_k127_2249582_14 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K00760,K04075 - 2.4.2.8,6.3.4.19 0.00000000000000000000000000000000001062 149.0
HFD3_k127_2249582_15 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000203 121.0
HFD3_k127_2249582_16 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000005368 113.0
HFD3_k127_2249582_17 Lipopolysaccharide-assembly - - - 0.000000000000001394 83.0
HFD3_k127_2249582_18 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000009782 75.0
HFD3_k127_2249582_19 N-formylglutamate amidohydrolase - - - 0.000000006329 63.0
HFD3_k127_2249582_2 Peptidase S46 - - - 2.651e-230 732.0
HFD3_k127_2249582_20 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase - - - 0.00054 51.0
HFD3_k127_2249582_3 PFAM UvrD REP helicase K03657 - 3.6.4.12 6.063e-219 703.0
HFD3_k127_2249582_4 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 405.0
HFD3_k127_2249582_5 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 411.0
HFD3_k127_2249582_6 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003237 379.0
HFD3_k127_2249582_7 Required for morphogenesis under gluconeogenic growth conditions - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007549 319.0
HFD3_k127_2249582_8 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 307.0
HFD3_k127_2249582_9 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001405 284.0
HFD3_k127_2255261_0 Heat shock 70 kDa protein K04043 - - 1.551e-292 909.0
HFD3_k127_2255261_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 3.686e-259 812.0
HFD3_k127_2255261_10 MerR HTH family regulatory protein K13640 - - 0.000000000000000000000000000000000009501 142.0
HFD3_k127_2255261_11 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41 0.000000000000000000000000000008475 126.0
HFD3_k127_2255261_12 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.0000000000000000002913 93.0
HFD3_k127_2255261_2 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009568 479.0
HFD3_k127_2255261_3 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 418.0
HFD3_k127_2255261_4 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007308 402.0
HFD3_k127_2255261_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 388.0
HFD3_k127_2255261_6 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005757 357.0
HFD3_k127_2255261_7 Metallophosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000005649 192.0
HFD3_k127_2255261_8 - - - - 0.0000000000000000000000000000000000000000000000001943 183.0
HFD3_k127_2255261_9 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000009107 169.0
HFD3_k127_227288_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 403.0
HFD3_k127_227288_2 ketosteroid isomerase - - - 0.000000000000003219 75.0
HFD3_k127_2306360_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K03737 - 1.2.7.1 0.0 1700.0
HFD3_k127_2306360_1 Carboxypeptidase regulatory-like domain - - - 0.0 1159.0
HFD3_k127_2306360_10 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 447.0
HFD3_k127_2306360_11 Putative glucoamylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 429.0
HFD3_k127_2306360_12 Cytochrome c554 and c-prime K03620 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 413.0
HFD3_k127_2306360_13 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000524 348.0
HFD3_k127_2306360_14 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 306.0
HFD3_k127_2306360_15 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 299.0
HFD3_k127_2306360_16 introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008585 266.0
HFD3_k127_2306360_17 Di-haem oxidoreductase, putative peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001205 267.0
HFD3_k127_2306360_18 Periplasmic protein thiol K02199 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001366 249.0
HFD3_k127_2306360_19 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000000000000000000000000000002097 250.0
HFD3_k127_2306360_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1091.0
HFD3_k127_2306360_20 Belongs to the P-Pant transferase superfamily K06133 - - 0.000000000000000000000000000000000000000000000000000000000000000002574 234.0
HFD3_k127_2306360_21 - - - - 0.000000000000000000000000000000000000000000000000000000002764 224.0
HFD3_k127_2306360_22 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000000000000000000000000000586 199.0
HFD3_k127_2306360_23 Tetratricopeptide repeat K02200 - - 0.0000000000000000000000000000000000000000000000000000002746 208.0
HFD3_k127_2306360_24 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.00000000000000000000000000000000000000000000000002789 182.0
HFD3_k127_2306360_25 subunit of a heme lyase K02200 - - 0.000000000000000000000000000000000000000000001733 169.0
HFD3_k127_2306360_26 Acetyltransferase (GNAT) domain K03825 - - 0.00000000000000000000000000000000000000000002449 168.0
HFD3_k127_2306360_28 PFAM Transcription regulator MerR DNA binding K08365,K13638 GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045893,GO:0045935,GO:0046483,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000000416 119.0
HFD3_k127_2306360_29 12 heme-binding sites - - - 0.00000000000000000004145 102.0
HFD3_k127_2306360_3 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0 1061.0
HFD3_k127_2306360_30 Evidence 4 Homologs of previously reported genes of K03975 - - 0.000000000000121 76.0
HFD3_k127_2306360_31 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.0000004544 54.0
HFD3_k127_2306360_32 Class III cytochrome C family - - - 0.00001672 54.0
HFD3_k127_2306360_33 Tetratricopeptide TPR_2 repeat protein - - - 0.00004881 53.0
HFD3_k127_2306360_34 PQQ-like domain - - - 0.00008221 55.0
HFD3_k127_2306360_35 heat shock protein binding - - - 0.0004274 52.0
HFD3_k127_2306360_4 iron-nicotianamine transmembrane transporter activity - GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.0 1014.0
HFD3_k127_2306360_5 Cytochrome c-type biogenesis protein CcmF K02198 - - 1.45e-304 945.0
HFD3_k127_2306360_6 hydrolase, family 3 K05349 - 3.2.1.21 1.543e-265 836.0
HFD3_k127_2306360_7 CHASE3 domain - - - 3.413e-246 775.0
HFD3_k127_2306360_8 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 589.0
HFD3_k127_2306360_9 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 554.0
HFD3_k127_2339247_0 Tricorn protease C1 domain K08676 - - 0.0 1265.0
HFD3_k127_2339247_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 8.695e-230 730.0
HFD3_k127_2339247_10 aminotransferase class I and II K10907 - - 0.00000000000000000000000000000000000000000000000000000000008291 219.0
HFD3_k127_2339247_11 PFAM phospholipase Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000003955 207.0
HFD3_k127_2339247_12 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000000000000000003095 179.0
HFD3_k127_2339247_13 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000003423 186.0
HFD3_k127_2339247_14 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000926 143.0
HFD3_k127_2339247_15 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000189 126.0
HFD3_k127_2339247_16 Ankyrin repeat - - - 0.00000000000000000000000006342 118.0
HFD3_k127_2339247_17 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000003675 108.0
HFD3_k127_2339247_18 response regulator, receiver - - - 0.000000000000000000000001934 112.0
HFD3_k127_2339247_19 Cupin 2, conserved barrel domain protein K21700 - - 0.000000000000000562 82.0
HFD3_k127_2339247_2 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 583.0
HFD3_k127_2339247_20 Pfam Plasmid stabilisation system protein - - - 0.0000002377 54.0
HFD3_k127_2339247_3 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006359 552.0
HFD3_k127_2339247_4 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000401 410.0
HFD3_k127_2339247_5 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 355.0
HFD3_k127_2339247_6 dna ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008978 353.0
HFD3_k127_2339247_7 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007099 342.0
HFD3_k127_2339247_8 WD40-like Beta Propeller Repeat - GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 306.0
HFD3_k127_2339247_9 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000003478 241.0
HFD3_k127_2440667_0 Tricorn protease homolog - - - 0.0 1341.0
HFD3_k127_2440667_1 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 300.0
HFD3_k127_2440667_2 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000001625 220.0
HFD3_k127_2442136_0 efflux transmembrane transporter activity - - - 6.793e-235 751.0
HFD3_k127_2442136_1 metal ion transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 598.0
HFD3_k127_2442136_2 epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006739 325.0
HFD3_k127_2442136_3 Cupin - - - 0.0000000000000000000000000000000000000000001425 164.0
HFD3_k127_2442136_4 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000005059 140.0
HFD3_k127_2450490_0 Carboxyl transferase domain - - - 6.689e-236 743.0
HFD3_k127_2450490_1 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 537.0
HFD3_k127_2450490_10 Zn peptidase - - - 0.00000000000000000000000000000000000000000000000000000000001768 222.0
HFD3_k127_2450490_11 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000006276 178.0
HFD3_k127_2450490_12 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000004451 145.0
HFD3_k127_2450490_13 PFAM thioesterase superfamily K07107 - - 0.0000000000000000000000000000000000001933 147.0
HFD3_k127_2450490_14 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000001664 139.0
HFD3_k127_2450490_15 Protein of unknown function (DUF3311) - - - 0.000000000000129 73.0
HFD3_k127_2450490_16 - - - - 0.000000000001563 70.0
HFD3_k127_2450490_17 Protein of unknown function (DUF433) - - - 0.000000000001602 72.0
HFD3_k127_2450490_18 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000005418 56.0
HFD3_k127_2450490_2 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 460.0
HFD3_k127_2450490_3 Iron-containing alcohol dehydrogenase K00001,K13954 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 407.0
HFD3_k127_2450490_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 370.0
HFD3_k127_2450490_5 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000744 336.0
HFD3_k127_2450490_6 protein kinase related protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 310.0
HFD3_k127_2450490_7 PFAM Metallophosphoesterase K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 287.0
HFD3_k127_2450490_8 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001577 277.0
HFD3_k127_2450490_9 PFAM regulatory protein LuxR - - - 0.00000000000000000000000000000000000000000000000000000000000437 215.0
HFD3_k127_247328_0 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 619.0
HFD3_k127_247328_1 phosphorelay signal transduction system K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006697 409.0
HFD3_k127_247328_2 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008836 306.0
HFD3_k127_247328_3 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 306.0
HFD3_k127_247328_4 Pyridoxamine 5'-phosphate oxidase like - - - 0.0000000000000000000000000000000000000000000000000000000000003788 215.0
HFD3_k127_247328_5 COG1943 Transposase and inactivated derivatives - - - 0.00006573 53.0
HFD3_k127_2485120_0 Polysulphide reductase, NrfD - - - 1.022e-198 629.0
HFD3_k127_2485120_1 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 575.0
HFD3_k127_2485120_2 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 361.0
HFD3_k127_2485120_3 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 340.0
HFD3_k127_2485120_4 Cytochrome c K00413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 331.0
HFD3_k127_2485120_5 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.0000000000000000000000000000000000000000000000000000000000000000001446 259.0
HFD3_k127_2485120_6 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000006585 121.0
HFD3_k127_2485120_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000001126 72.0
HFD3_k127_2485120_8 two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.0004512 44.0
HFD3_k127_2637802_0 Prolyl oligopeptidase family - - - 1.419e-265 836.0
HFD3_k127_2637802_1 Dienelactone hydrolase family - - - 4.91e-237 751.0
HFD3_k127_2637802_10 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000002461 199.0
HFD3_k127_2637802_11 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000000000000000000000000001369 173.0
HFD3_k127_2637802_12 Putative zinc-finger - - - 0.0000000000000000000000000000000000000000000008948 177.0
HFD3_k127_2637802_13 Lysin motif - - - 0.000000000000000000000000000000000000000004253 160.0
HFD3_k127_2637802_2 IgA Peptidase M64 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008406 613.0
HFD3_k127_2637802_3 cytochrome C peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 609.0
HFD3_k127_2637802_4 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 517.0
HFD3_k127_2637802_5 Glucose Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 435.0
HFD3_k127_2637802_6 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000004458 256.0
HFD3_k127_2637802_7 Calcineurin-like phosphoesterase superfamily domain K07498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000638 240.0
HFD3_k127_2637802_8 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.00000000000000000000000000000000000000000000000000000000000002745 220.0
HFD3_k127_2637802_9 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.00000000000000000000000000000000000000000000000000000000000003915 221.0
HFD3_k127_272198_0 Peptidase M14, carboxypeptidase A - - - 0.0 1390.0
HFD3_k127_272198_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1052.0
HFD3_k127_272198_10 Cys/Met metabolism PLP-dependent enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 392.0
HFD3_k127_272198_11 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K04105,K04110 - 6.2.1.25,6.2.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 388.0
HFD3_k127_272198_12 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008737 357.0
HFD3_k127_272198_13 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 358.0
HFD3_k127_272198_14 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 327.0
HFD3_k127_272198_15 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005555 281.0
HFD3_k127_272198_16 PFAM thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000005851 236.0
HFD3_k127_272198_17 GAF domain K08968 - 1.8.4.14 0.00000000000000000000000000000000000000000000000000000002091 202.0
HFD3_k127_272198_18 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000000000000000000000000187 191.0
HFD3_k127_272198_19 Scaffold protein Nfu/NifU N terminal - - - 0.00000000000000000000000000000000000000000000000000007007 193.0
HFD3_k127_272198_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 669.0
HFD3_k127_272198_20 Belongs to the glycosyl hydrolase 5 (cellulase A) family K19355 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0004567,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010412,GO:0015923,GO:0016052,GO:0016787,GO:0016798,GO:0016985,GO:0016998,GO:0043170,GO:0044036,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0046355,GO:0071554,GO:0071704,GO:1901575 3.2.1.78 0.0000000000000000000000000000000000000000000000000006762 205.0
HFD3_k127_272198_21 GlcNAc-PI de-N-acetylase K01463 - - 0.000000000000000000000000000000000000000001977 163.0
HFD3_k127_272198_22 NlpC/P60 family K19223,K19224 - - 0.0000000000000317 81.0
HFD3_k127_272198_24 glycosyl transferase, family 39 - - - 0.0001613 54.0
HFD3_k127_272198_25 - - - - 0.0008962 48.0
HFD3_k127_272198_3 Elongation factor SelB, winged helix K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005178 540.0
HFD3_k127_272198_4 amino acid transport K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 527.0
HFD3_k127_272198_5 Belongs to the ALAD family K01698 GO:0000287,GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 420.0
HFD3_k127_272198_6 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 408.0
HFD3_k127_272198_7 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 404.0
HFD3_k127_272198_8 glycosyl transferase group 1 K00754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 407.0
HFD3_k127_272198_9 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004809 394.0
HFD3_k127_2732063_0 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000001901 225.0
HFD3_k127_2732063_1 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000004819 216.0
HFD3_k127_2732063_2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K08641,K11206 - 3.4.13.22 0.00000000001837 64.0
HFD3_k127_2732063_3 - - - - 0.000000006179 64.0
HFD3_k127_2732063_5 Baseplate assembly protein - - - 0.00007093 47.0
HFD3_k127_2745060_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 1.027e-219 702.0
HFD3_k127_2745060_1 Acyl-CoA dehydrogenase, C-terminal domain K16173 - 1.3.99.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 526.0
HFD3_k127_2745060_2 glycyl-tRNA aminoacylation K01880 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 499.0
HFD3_k127_2745060_3 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 404.0
HFD3_k127_2745060_4 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 384.0
HFD3_k127_2745060_5 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009508 361.0
HFD3_k127_2745060_6 beta-fructofuranosidase activity - - - 0.00000000000000000000000000000000000000000000000000000295 213.0
HFD3_k127_2745060_7 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.00000000000000000000000000000005312 127.0
HFD3_k127_2745060_8 - - - - 0.00000000000006612 76.0
HFD3_k127_2745060_9 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000002179 59.0
HFD3_k127_276288_0 dna ligase - - - 2.803e-223 698.0
HFD3_k127_276288_1 ATP dependent DNA ligase C terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006834 578.0
HFD3_k127_276288_10 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) K08964 - 4.2.1.109 0.00000000000000000000000000000000000000000000000000000000000005954 219.0
HFD3_k127_276288_11 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000002245 149.0
HFD3_k127_276288_12 peptidyl-tyrosine sulfation K03217,K06872 - - 0.000000000000000000000000000000002116 142.0
HFD3_k127_276288_13 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.000000000002109 74.0
HFD3_k127_276288_14 Protein of unknown function (DUF433) - - - 0.000001669 53.0
HFD3_k127_276288_2 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 411.0
HFD3_k127_276288_3 H( )-stimulated, divalent metal cation uptake system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 395.0
HFD3_k127_276288_4 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007267 387.0
HFD3_k127_276288_5 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008655 383.0
HFD3_k127_276288_6 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 383.0
HFD3_k127_276288_7 Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene) K09880 - 3.1.3.77 0.000000000000000000000000000000000000000000000000000000000000000000000001535 252.0
HFD3_k127_276288_8 Beta-lactamase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003799 255.0
HFD3_k127_276288_9 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway K08967 - 1.13.11.53,1.13.11.54 0.0000000000000000000000000000000000000000000000000000000000000000001071 237.0
HFD3_k127_2783168_0 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 6.508e-258 808.0
HFD3_k127_2783168_1 tetratricopeptide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008795 535.0
HFD3_k127_2783168_10 Domain of unknown function (DUF4132) - - - 0.000009517 58.0
HFD3_k127_2783168_2 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity K03429 - 2.4.1.315 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 501.0
HFD3_k127_2783168_3 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 462.0
HFD3_k127_2783168_4 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003207 296.0
HFD3_k127_2783168_5 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000001538 216.0
HFD3_k127_2783168_6 - - - - 0.0000000000000000000000000000000000000000000001547 176.0
HFD3_k127_2783168_8 cellulase activity - - - 0.0000000000000000004315 102.0
HFD3_k127_2783168_9 Outer membrane protein (OmpH-like) K06142 - - 0.00000001823 63.0
HFD3_k127_2864482_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 5.022e-236 739.0
HFD3_k127_2864482_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 1.357e-214 683.0
HFD3_k127_2864482_10 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000007066 226.0
HFD3_k127_2864482_11 VanZ like family - - - 0.0000000000000000000000000009526 118.0
HFD3_k127_2864482_12 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.000000000000000000000000002504 111.0
HFD3_k127_2864482_13 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000001301 113.0
HFD3_k127_2864482_14 Jag_N K06346 - - 0.000000000000000000000001531 109.0
HFD3_k127_2864482_15 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000001341 68.0
HFD3_k127_2864482_16 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000002598 65.0
HFD3_k127_2864482_17 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000005217 64.0
HFD3_k127_2864482_18 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000001397 56.0
HFD3_k127_2864482_19 Methyltransferase domain - - - 0.00003133 51.0
HFD3_k127_2864482_2 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 495.0
HFD3_k127_2864482_20 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.0002804 50.0
HFD3_k127_2864482_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 446.0
HFD3_k127_2864482_4 virion core protein (lumpy skin disease virus) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 403.0
HFD3_k127_2864482_5 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 385.0
HFD3_k127_2864482_6 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 326.0
HFD3_k127_2864482_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 304.0
HFD3_k127_2864482_8 Sporulation initiation inhibitor protein Soj K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 297.0
HFD3_k127_2864482_9 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002255 259.0
HFD3_k127_2867769_0 Prolyl oligopeptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 566.0
HFD3_k127_2867769_1 Nuclease K07004 - - 0.00000000008211 72.0
HFD3_k127_2867769_2 PFAM Transposase IS200-like K07491 - - 0.0000001173 63.0
HFD3_k127_2867769_3 Transposase K07491 - - 0.00002673 55.0
HFD3_k127_2934392_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 536.0
HFD3_k127_2934392_1 PFAM Cache K08738 - - 0.000000000000000000000000000000000000000000000000000000000000000002552 248.0
HFD3_k127_2934392_2 - - - - 0.0000000000000000000000000000000000000000000009441 173.0
HFD3_k127_2934392_3 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000007594 136.0
HFD3_k127_2934392_4 COG0840 Methyl-accepting chemotaxis protein - - - 0.00000000000000000000005173 115.0
HFD3_k127_2934392_5 SIR2-like domain - - - 0.0000000000006621 79.0
HFD3_k127_2934392_6 - - - - 0.0000000003404 70.0
HFD3_k127_2934392_7 PLD-like domain K17717 - 3.1.4.4 0.00000001402 67.0
HFD3_k127_2936851_0 Protein tyrosine kinase - - - 4.129e-201 656.0
HFD3_k127_2936851_1 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 481.0
HFD3_k127_2936851_2 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 445.0
HFD3_k127_2936851_3 Belongs to the MIP aquaporin (TC 1.A.8) family K02440,K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 352.0
HFD3_k127_2936851_4 Rieske [2Fe-2S] domain K15060 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005865 341.0
HFD3_k127_2936851_5 TIGRFAM thioredoxin K03672 - 1.8.1.8 0.00000000000000000000000000000000000000001026 158.0
HFD3_k127_2936851_6 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000001982 170.0
HFD3_k127_2936851_7 - - - - 0.0000000000001395 80.0
HFD3_k127_3013965_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1287.0
HFD3_k127_3013965_1 Belongs to the aldehyde dehydrogenase family K00128,K00146 - 1.2.1.3,1.2.1.39 5.514e-198 632.0
HFD3_k127_3013965_10 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000000000001305 189.0
HFD3_k127_3013965_11 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.000000000000000000000000000000000000000000000002575 184.0
HFD3_k127_3013965_13 TPR repeat - - - 0.0000000000000000000002137 103.0
HFD3_k127_3013965_14 - - - - 0.000000006329 63.0
HFD3_k127_3013965_15 - - - - 0.000009213 52.0
HFD3_k127_3013965_2 UDP binding domain K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 544.0
HFD3_k127_3013965_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000056 491.0
HFD3_k127_3013965_4 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 430.0
HFD3_k127_3013965_5 TonB-dependent Receptor Plug Domain K02014,K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 400.0
HFD3_k127_3013965_6 NAD(P)H-binding K01784,K02473 - 5.1.3.2,5.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 358.0
HFD3_k127_3013965_7 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005071 250.0
HFD3_k127_3013965_8 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000008103 229.0
HFD3_k127_3013965_9 Abc transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000005562 200.0
HFD3_k127_3044184_0 lipopolysaccharide transport K22110 - - 0.0 1039.0
HFD3_k127_3044184_1 alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 561.0
HFD3_k127_3044184_2 Glycogen debranching enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002969 284.0
HFD3_k127_3044184_3 Mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000418 217.0
HFD3_k127_306963_0 Sulfate permease family K01673,K03321 - 4.2.1.1 5.204e-199 634.0
HFD3_k127_306963_1 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007172 366.0
HFD3_k127_306963_2 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000002238 247.0
HFD3_k127_306963_3 acylphosphatase activity K01512 - 3.6.1.7 0.000000000000004185 79.0
HFD3_k127_3071125_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1341.0
HFD3_k127_3071125_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564 2.7.4.1 6.501e-206 662.0
HFD3_k127_3071125_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 291.0
HFD3_k127_3071125_11 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000178 271.0
HFD3_k127_3071125_12 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000008012 224.0
HFD3_k127_3071125_13 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000264 221.0
HFD3_k127_3071125_14 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.0000000000000000000000000000000000000000000000001292 180.0
HFD3_k127_3071125_15 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000004101 173.0
HFD3_k127_3071125_16 Protein of unknown function (DUF3465) - - - 0.0000000000000000000000000000000000000000001706 167.0
HFD3_k127_3071125_17 YCII-related domain - - - 0.00000000000000000000000000000000000002712 146.0
HFD3_k127_3071125_18 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000004514 144.0
HFD3_k127_3071125_19 Diadenosine tetraphosphatase and related serine threonine protein phosphatases K07313 - 3.1.3.16 0.0000000000000000000000000000000001947 140.0
HFD3_k127_3071125_2 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006746 572.0
HFD3_k127_3071125_20 Methyltransferase domain - - - 0.00000000000000000000000000357 121.0
HFD3_k127_3071125_21 Histidine kinase - - - 0.0000000000000000000000001039 110.0
HFD3_k127_3071125_22 catechol 1,2-dioxygenase - - - 0.0000000000000009592 87.0
HFD3_k127_3071125_24 DinB family - - - 0.000000000001611 74.0
HFD3_k127_3071125_25 Bacterial regulatory protein, Fis family K02481,K02667 - - 0.000000000001748 75.0
HFD3_k127_3071125_26 Domain of unknown function (DUF4956) - - - 0.0000000003739 70.0
HFD3_k127_3071125_27 - - - - 0.000000008761 68.0
HFD3_k127_3071125_28 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.000004197 58.0
HFD3_k127_3071125_29 - - - - 0.000215 44.0
HFD3_k127_3071125_3 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009422 554.0
HFD3_k127_3071125_30 ABC transporter, ATP-binding protein K06147 - - 0.0005221 45.0
HFD3_k127_3071125_31 nuclease - - - 0.0006958 50.0
HFD3_k127_3071125_4 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 514.0
HFD3_k127_3071125_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 430.0
HFD3_k127_3071125_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 389.0
HFD3_k127_3071125_7 PFAM phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 382.0
HFD3_k127_3071125_8 Forkhead associated domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 341.0
HFD3_k127_3071125_9 Protein of unknown function (DUF1211) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004612 296.0
HFD3_k127_3075772_0 Prolyl oligopeptidase family - - - 1.158e-199 642.0
HFD3_k127_3075772_1 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 489.0
HFD3_k127_3075772_10 Protein of unknown function (DUF4242) - - - 0.00000000000000000000000000000000000000005956 152.0
HFD3_k127_3075772_11 periplasmic or secreted lipoprotein - - - 0.000000000000000000000000000000000000004511 160.0
HFD3_k127_3075772_12 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000634 146.0
HFD3_k127_3075772_13 flavoprotein involved in K transport K07222 - - 0.00000000000000000000000008161 120.0
HFD3_k127_3075772_14 Protein of unknown function (DUF4231) - - - 0.00000000000000000002538 102.0
HFD3_k127_3075772_15 radical SAM domain protein - - - 0.000000000005956 71.0
HFD3_k127_3075772_2 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 473.0
HFD3_k127_3075772_3 beta' subunit K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007555 401.0
HFD3_k127_3075772_4 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004807 309.0
HFD3_k127_3075772_5 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 298.0
HFD3_k127_3075772_6 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000006502 262.0
HFD3_k127_3075772_7 PFAM OsmC family protein - - - 0.00000000000000000000000000000000000000000000000000000000000001339 220.0
HFD3_k127_3075772_8 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000006533 232.0
HFD3_k127_3075772_9 TonB-dependent Receptor Plug K02014 - - 0.0000000000000000000000000000000000000000000000000000000001102 216.0
HFD3_k127_3110382_0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0 2123.0
HFD3_k127_3110382_1 Peptidoglycan-binding domain 1 protein - - - 0.0 1848.0
HFD3_k127_3110382_10 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 465.0
HFD3_k127_3110382_11 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 420.0
HFD3_k127_3110382_12 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 410.0
HFD3_k127_3110382_13 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00018,K00058 - 1.1.1.29,1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006843 390.0
HFD3_k127_3110382_14 PFAM TonB-dependent Receptor Plug - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 400.0
HFD3_k127_3110382_15 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000096 368.0
HFD3_k127_3110382_16 Ferritin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 285.0
HFD3_k127_3110382_17 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003445 285.0
HFD3_k127_3110382_18 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001386 269.0
HFD3_k127_3110382_19 Tyrosine recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001773 263.0
HFD3_k127_3110382_2 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 0.0 1244.0
HFD3_k127_3110382_20 [2Fe-2S] binding domain - - - 0.00000000000000000000000000000000000000000000000000000000001281 210.0
HFD3_k127_3110382_21 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000663 203.0
HFD3_k127_3110382_22 Domain of unknown function (DUF1990) - - - 0.000000000000000000000000000000000000000000000000000000271 199.0
HFD3_k127_3110382_23 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000008951 199.0
HFD3_k127_3110382_24 iron ion homeostasis - - - 0.000000000000000000000000000000000000000000000000001258 207.0
HFD3_k127_3110382_25 peroxiredoxin activity - - - 0.0000000000000000000000000000000000000000000001167 175.0
HFD3_k127_3110382_26 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000004854 157.0
HFD3_k127_3110382_27 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000000000002599 152.0
HFD3_k127_3110382_28 acetyltransferase - - - 0.00000000000000000000000000000000000001167 149.0
HFD3_k127_3110382_29 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000001266 135.0
HFD3_k127_3110382_3 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1164.0
HFD3_k127_3110382_30 Amino-transferase class IV K00826 - 2.6.1.42 0.00000000000000000000000000000001189 138.0
HFD3_k127_3110382_31 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.0000000000000000000000000000000481 137.0
HFD3_k127_3110382_32 - - - - 0.00000000000000000000000000007331 121.0
HFD3_k127_3110382_33 Rhomboid family K19225 - 3.4.21.105 0.0000000000000000000000000000966 130.0
HFD3_k127_3110382_34 Phosphoglycerate mutase family - - - 0.0000000000000000000000001356 115.0
HFD3_k127_3110382_35 cell redox homeostasis - - - 0.000000000000000000000003423 109.0
HFD3_k127_3110382_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 6.242e-264 832.0
HFD3_k127_3110382_5 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K00256 - 1.3.99.16 8.978e-251 796.0
HFD3_k127_3110382_6 PFAM NHL repeat - - - 5.065e-201 648.0
HFD3_k127_3110382_7 PFAM Amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004095 599.0
HFD3_k127_3110382_8 Pkd domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 549.0
HFD3_k127_3110382_9 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 507.0
HFD3_k127_3117365_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2033.0
HFD3_k127_3117365_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1402.0
HFD3_k127_3117365_10 with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine K01658,K01664 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001632 271.0
HFD3_k127_3117365_11 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000001299 259.0
HFD3_k127_3117365_12 belongs to the PRA-CH family K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000002554 252.0
HFD3_k127_3117365_13 imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000003485 231.0
HFD3_k127_3117365_14 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000001696 231.0
HFD3_k127_3117365_15 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000007547 214.0
HFD3_k127_3117365_16 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000000000000000000000000000000000000000000000000000001154 207.0
HFD3_k127_3117365_17 HisG, C-terminal domain K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000005376 203.0
HFD3_k127_3117365_18 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000002984 170.0
HFD3_k127_3117365_19 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000002023 145.0
HFD3_k127_3117365_2 Belongs to the PEP-utilizing enzyme family K01006,K01007 - 2.7.9.1,2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 589.0
HFD3_k127_3117365_20 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000132 113.0
HFD3_k127_3117365_3 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 447.0
HFD3_k127_3117365_4 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005229 411.0
HFD3_k127_3117365_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007012 357.0
HFD3_k127_3117365_6 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 310.0
HFD3_k127_3117365_7 Inositol monophosphatase family K01092,K05602 - 3.1.3.15,3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 296.0
HFD3_k127_3117365_8 PFAM Pyridoxal-dependent decarboxylase conserved domain K01580,K01593,K13745 - 4.1.1.105,4.1.1.15,4.1.1.28,4.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 303.0
HFD3_k127_3117365_9 oxidoreductase activity, acting on CH-OH group of donors K13237 - 1.3.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 289.0
HFD3_k127_3142435_0 Glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005741 532.0
HFD3_k127_3142435_1 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005961 356.0
HFD3_k127_3142435_2 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 295.0
HFD3_k127_3142435_3 Domain of unknown function (DUF4136) - - - 0.00000000000000000000000000000000000000000000003962 175.0
HFD3_k127_3142435_4 Belongs to the ompA family - - - 0.000000000000000000003563 105.0
HFD3_k127_3142435_5 - - - - 0.0000000000000000001556 93.0
HFD3_k127_3142435_6 PFAM amidohydrolase - - - 0.000002064 51.0
HFD3_k127_314485_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702,K08999 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 9.312e-269 843.0
HFD3_k127_314485_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 4.626e-267 830.0
HFD3_k127_314485_10 zinc metalloprotease K11749 - - 0.000000000002576 74.0
HFD3_k127_314485_11 Tetratricopeptide repeat - - - 0.000000003282 69.0
HFD3_k127_314485_12 PFAM helix-turn-helix, Fis-type - - - 0.0000004889 54.0
HFD3_k127_314485_13 Domain of unknown function (DUF4388) - - - 0.000001113 59.0
HFD3_k127_314485_14 - - - - 0.000001818 60.0
HFD3_k127_314485_2 PFAM FAD linked oxidase domain protein K00102 - 1.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000573 523.0
HFD3_k127_314485_3 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 444.0
HFD3_k127_314485_4 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 363.0
HFD3_k127_314485_5 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006721 303.0
HFD3_k127_314485_6 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000001791 244.0
HFD3_k127_314485_7 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000003094 201.0
HFD3_k127_314485_8 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000000006055 156.0
HFD3_k127_314485_9 DinB family - - - 0.000000000000000000007376 98.0
HFD3_k127_3242038_0 PrkA AAA domain protein K07180 - - 9.408e-306 948.0
HFD3_k127_3242038_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 9.355e-265 842.0
HFD3_k127_3242038_10 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003551 279.0
HFD3_k127_3242038_11 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004371 274.0
HFD3_k127_3242038_12 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000006861 231.0
HFD3_k127_3242038_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000006378 229.0
HFD3_k127_3242038_14 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000001322 226.0
HFD3_k127_3242038_15 COG1520 FOG WD40-like repeat - - - 0.000000000000000000000000000000000000000000257 173.0
HFD3_k127_3242038_16 PFAM Ubiquitin-conjugating - - - 0.0000000000000000000000000000000000000000007262 170.0
HFD3_k127_3242038_17 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000005133 157.0
HFD3_k127_3242038_18 histone H2A K63-linked ubiquitination - - - 0.00000000000000000000000000000000000000002185 166.0
HFD3_k127_3242038_19 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000003127 162.0
HFD3_k127_3242038_2 SpoVR like protein K06415 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 562.0
HFD3_k127_3242038_20 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000001418 151.0
HFD3_k127_3242038_21 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.000000000000000000000000000000001903 144.0
HFD3_k127_3242038_22 proteolysis - - - 0.00000000000000000000000000000001002 141.0
HFD3_k127_3242038_23 WXG100 protein secretion system (Wss), protein YukD - - - 0.00000000000000000000000000008758 118.0
HFD3_k127_3242038_24 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000001445 115.0
HFD3_k127_3242038_25 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000008564 116.0
HFD3_k127_3242038_26 Trm112p-like protein K09791 - - 0.00000000000000000000006085 99.0
HFD3_k127_3242038_27 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000001482 101.0
HFD3_k127_3242038_28 3D domain - - - 0.000000000000000003955 91.0
HFD3_k127_3242038_3 Belongs to the UPF0229 family K09786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006467 487.0
HFD3_k127_3242038_30 Bacterial PH domain K08981 - - 0.0000000052 65.0
HFD3_k127_3242038_31 Modulates RecA activity K03565 - - 0.0000001087 60.0
HFD3_k127_3242038_32 Putative peptidoglycan binding domain - - - 0.0000001356 58.0
HFD3_k127_3242038_34 Domain of unknown function (DUF4388) K12132 - 2.7.11.1 0.00008808 53.0
HFD3_k127_3242038_4 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 422.0
HFD3_k127_3242038_5 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006347 335.0
HFD3_k127_3242038_6 L-asparaginase II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005141 305.0
HFD3_k127_3242038_7 D-alanyl-d-alanine carboxypeptidase K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 311.0
HFD3_k127_3242038_8 Trypsin-like peptidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005057 293.0
HFD3_k127_3242038_9 Inorganic pyrophosphatase K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002086 281.0
HFD3_k127_3254948_0 arylsulfatase activity K01130 - 3.1.6.1 0.0 1304.0
HFD3_k127_3254948_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.201e-215 682.0
HFD3_k127_3254948_10 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002 251.0
HFD3_k127_3254948_11 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000038 254.0
HFD3_k127_3254948_12 iron-sulfur cluster biosynthesis transcriptional regulator SufR K09012 - - 0.00000000000000000000000000000000000000000000000000000000000000000007124 237.0
HFD3_k127_3254948_13 Belongs to the MlaE permease family K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000396 237.0
HFD3_k127_3254948_14 Cytidylyltransferase K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000007366 230.0
HFD3_k127_3254948_15 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000008852 242.0
HFD3_k127_3254948_16 Bacteriocin-protection protein - - - 0.0000000000000000000000000000000000000000000000000000000000428 212.0
HFD3_k127_3254948_17 -acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000003528 198.0
HFD3_k127_3254948_18 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000933 203.0
HFD3_k127_3254948_19 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000005039 193.0
HFD3_k127_3254948_2 cytochrome p450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 443.0
HFD3_k127_3254948_20 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000006601 180.0
HFD3_k127_3254948_21 Protein of unknown function (DUF2490) - - - 0.00000000000000000000000000000000006508 142.0
HFD3_k127_3254948_22 Helix-turn-helix domain K03088 - - 0.000000000000000000000000000003859 127.0
HFD3_k127_3254948_23 Peptidase M56 - - - 0.000000000000000000000001596 115.0
HFD3_k127_3254948_24 iron assimilation - - - 0.000000784 53.0
HFD3_k127_3254948_25 - - - - 0.000009475 49.0
HFD3_k127_3254948_3 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004492 399.0
HFD3_k127_3254948_4 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 366.0
HFD3_k127_3254948_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441 356.0
HFD3_k127_3254948_6 Belongs to the KdsA family K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007726 338.0
HFD3_k127_3254948_7 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 337.0
HFD3_k127_3254948_8 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 345.0
HFD3_k127_3254948_9 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 302.0
HFD3_k127_3267871_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 5.576e-270 854.0
HFD3_k127_3267871_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 9.475e-195 618.0
HFD3_k127_3267871_10 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000000000000000000000000000005829 250.0
HFD3_k127_3267871_11 Transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000000000000000000000006829 175.0
HFD3_k127_3267871_12 Cation transport regulator - - - 0.00000000000000000000000000000000000000000000003355 175.0
HFD3_k127_3267871_14 DinB superfamily - - - 0.0000000000000000000000000000000000004438 146.0
HFD3_k127_3267871_15 N-acetyl-alpha-D-glucosaminyl L-malate synthase K00754 - - 0.000000000000000000000000000000007362 141.0
HFD3_k127_3267871_16 FR47-like protein - - - 0.0000000000000000000000000000001798 130.0
HFD3_k127_3267871_17 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000006962 131.0
HFD3_k127_3267871_18 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000002377 123.0
HFD3_k127_3267871_19 4Fe-4S single cluster domain of Ferredoxin I - - - 0.00000000000000000000000001282 110.0
HFD3_k127_3267871_2 6-phosphogluconolactonase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 530.0
HFD3_k127_3267871_20 - - - - 0.000000000000000000000003176 103.0
HFD3_k127_3267871_21 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000004846 102.0
HFD3_k127_3267871_22 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00363,K05710 - 1.7.1.15 0.00000000000000000008997 94.0
HFD3_k127_3267871_23 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000001033 93.0
HFD3_k127_3267871_24 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000001366 102.0
HFD3_k127_3267871_25 - - - - 0.000000000003791 76.0
HFD3_k127_3267871_26 - - - - 0.000000000003997 70.0
HFD3_k127_3267871_27 CsbD-like - - - 0.0000000001154 64.0
HFD3_k127_3267871_28 Endonuclease/Exonuclease/phosphatase family K07004 - - 0.00000000145 74.0
HFD3_k127_3267871_3 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 453.0
HFD3_k127_3267871_30 amine dehydrogenase activity K01179,K01406,K07004 - 3.2.1.4,3.4.24.40 0.00001628 60.0
HFD3_k127_3267871_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 367.0
HFD3_k127_3267871_5 Phage Tail Collar Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 297.0
HFD3_k127_3267871_6 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 310.0
HFD3_k127_3267871_7 PFAM Phage Tail Collar - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000439 273.0
HFD3_k127_3267871_8 Phage Tail Collar Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001224 264.0
HFD3_k127_3267871_9 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001916 273.0
HFD3_k127_3270687_0 ABC1 family K03688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005622 573.0
HFD3_k127_3270687_1 ATP dependent DNA ligase C terminal region K10747 GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 563.0
HFD3_k127_3270687_10 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000001334 211.0
HFD3_k127_3270687_11 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.00000000000000000000000000000000000000000000000002469 186.0
HFD3_k127_3270687_12 EVE domain - - - 0.000000000000000000000000000000000000000000000001407 177.0
HFD3_k127_3270687_13 Alpha/beta hydrolase family K06889 - - 0.000000000000000000000000000000000000001075 158.0
HFD3_k127_3270687_14 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000000008883 158.0
HFD3_k127_3270687_15 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000003429 146.0
HFD3_k127_3270687_16 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 0.000000000000000000000000000000002322 135.0
HFD3_k127_3270687_17 mttA/Hcf106 family K03116,K03117 - - 0.00000000000112 73.0
HFD3_k127_3270687_18 Serine Threonine protein kinase K12132 - 2.7.11.1 0.000002168 60.0
HFD3_k127_3270687_2 Peptidase M56 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000856 494.0
HFD3_k127_3270687_3 Sodium:sulfate symporter transmembrane region K03319 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005062 446.0
HFD3_k127_3270687_4 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 419.0
HFD3_k127_3270687_5 Peptidase M56 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 391.0
HFD3_k127_3270687_6 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006085 342.0
HFD3_k127_3270687_7 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000631 318.0
HFD3_k127_3270687_8 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001933 286.0
HFD3_k127_3270687_9 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001615 290.0
HFD3_k127_3297037_0 Cytochrome C oxidase subunit II, periplasmic domain K00376 - 1.7.2.4 2.791e-299 927.0
HFD3_k127_3297037_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 9.179e-243 767.0
HFD3_k127_3297037_10 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 450.0
HFD3_k127_3297037_11 FAD dependent oxidoreductase K00303,K21061 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008083 436.0
HFD3_k127_3297037_12 Proline racemase K12658 - 5.1.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 431.0
HFD3_k127_3297037_13 Dihydrodipicolinate synthetase family K21062 - 3.5.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 416.0
HFD3_k127_3297037_14 Domain of unknown function (DUF4178) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 426.0
HFD3_k127_3297037_15 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005611 421.0
HFD3_k127_3297037_16 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 404.0
HFD3_k127_3297037_17 Major intrinsic protein K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 326.0
HFD3_k127_3297037_18 Glycogen recognition site of AMP-activated protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 324.0
HFD3_k127_3297037_19 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 323.0
HFD3_k127_3297037_2 Spermine/spermidine synthase domain K00797 - 2.5.1.16 9.919e-196 621.0
HFD3_k127_3297037_20 4 iron, 4 sulfur cluster binding K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 308.0
HFD3_k127_3297037_21 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 288.0
HFD3_k127_3297037_22 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000002193 269.0
HFD3_k127_3297037_23 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000003616 228.0
HFD3_k127_3297037_24 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000002132 229.0
HFD3_k127_3297037_25 lipoprotein involved in nitrous oxide reduction - - - 0.0000000000000000000000000000000000000000000000000000000006466 208.0
HFD3_k127_3297037_26 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.00000000000000000000000000000000000000000000000000000006929 204.0
HFD3_k127_3297037_27 - - - - 0.0000000000000000000000000000000000000000000000000000002026 200.0
HFD3_k127_3297037_28 Ndr family - - - 0.0000000000000000000000000000000000000000000000000000002052 217.0
HFD3_k127_3297037_29 methyltransferase K05928 - 2.1.1.95 0.000000000000000000000000000000000000000000000000000002213 201.0
HFD3_k127_3297037_3 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007115 609.0
HFD3_k127_3297037_30 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000000000000000000000000000000007716 189.0
HFD3_k127_3297037_31 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000109 184.0
HFD3_k127_3297037_32 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000004846 178.0
HFD3_k127_3297037_33 YwiC-like protein - - - 0.00000000000000000000000000000000000000000003756 170.0
HFD3_k127_3297037_34 - - - - 0.000000000000000000000000000000000000001399 152.0
HFD3_k127_3297037_35 Peptidase family M54 K06974 - - 0.0000000000000000000000000000000000001482 147.0
HFD3_k127_3297037_36 PFAM glycine cleavage H-protein - - - 0.000000000000000000000000000000003676 138.0
HFD3_k127_3297037_37 S-adenosylmethionine decarboxylase K01611 - 4.1.1.50 0.0000000000000000000000000001141 121.0
HFD3_k127_3297037_38 Cupin domain protein - - - 0.000000000000000000000000001232 117.0
HFD3_k127_3297037_39 2Fe-2S iron-sulfur cluster binding domain K00302 - 1.5.3.1 0.0000000000000000000000566 101.0
HFD3_k127_3297037_4 NAD(P)-binding Rossmann-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005701 569.0
HFD3_k127_3297037_40 Transglycosylase associated protein - - - 0.00000000000000000000007746 100.0
HFD3_k127_3297037_41 domain protein - - - 0.0000000000000000000002651 112.0
HFD3_k127_3297037_42 hydroperoxide reductase activity - - - 0.00000000000000000001286 94.0
HFD3_k127_3297037_43 domain protein - - - 0.000000000000000000126 104.0
HFD3_k127_3297037_44 Domain of unknown function (DUF4178) - - - 0.000000000000000004483 87.0
HFD3_k127_3297037_45 Domain of Unknown Function (DUF350) - - - 0.0000000000000001945 82.0
HFD3_k127_3297037_46 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000404 85.0
HFD3_k127_3297037_48 NAD dependent epimerase dehydratase family protein K01784 - 5.1.3.2 0.00000000097 69.0
HFD3_k127_3297037_49 Transmembrane anti-sigma factor - - - 0.000000005918 61.0
HFD3_k127_3297037_5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007674 558.0
HFD3_k127_3297037_50 Putative zinc-finger - - - 0.0000001698 57.0
HFD3_k127_3297037_51 12 heme-binding sites - - - 0.0002113 54.0
HFD3_k127_3297037_52 3D domain - - - 0.000666 50.0
HFD3_k127_3297037_6 phosphorelay signal transduction system K02481,K07713,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 520.0
HFD3_k127_3297037_7 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 529.0
HFD3_k127_3297037_8 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 470.0
HFD3_k127_3297037_9 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 452.0
HFD3_k127_3341397_0 homoserine dehydrogenase K12524 - 1.1.1.3,2.7.2.4 2.075e-245 782.0
HFD3_k127_3341397_1 Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005793 481.0
HFD3_k127_3341397_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.7.7.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 449.0
HFD3_k127_3341397_3 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 413.0
HFD3_k127_3341397_4 Bacterial protein of unknown function (DUF899) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 338.0
HFD3_k127_3341397_5 at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA) K04751 - - 0.0000000000000000000000000000000000000000000959 162.0
HFD3_k127_3341397_6 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000009152 136.0
HFD3_k127_3341397_8 - - - - 0.00000000000000000000000000002692 121.0
HFD3_k127_3341397_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00002578 47.0
HFD3_k127_335542_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.0 1025.0
HFD3_k127_335542_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372,K02567 - - 1.222e-286 898.0
HFD3_k127_335542_10 Histidine kinase K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009588 333.0
HFD3_k127_335542_11 response regulator, receiver K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 302.0
HFD3_k127_335542_12 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 294.0
HFD3_k127_335542_13 nitrite transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004484 300.0
HFD3_k127_335542_14 Alpha-aspartyl dipeptidase-like K05995 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.13.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005857 291.0
HFD3_k127_335542_15 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002986 270.0
HFD3_k127_335542_16 Domain of Unknown function (DUF542) K07322 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005438 244.0
HFD3_k127_335542_18 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002372 232.0
HFD3_k127_335542_19 phosphorelay signal transduction system K02490 - - 0.000000000000000000000000000000000000000000009145 173.0
HFD3_k127_335542_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 5.017e-277 861.0
HFD3_k127_335542_20 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000000000000000000009305 154.0
HFD3_k127_335542_21 Lysine methyltransferase - - - 0.000000000000000000000000000000000000004379 156.0
HFD3_k127_335542_22 oxidoreductase activity, acting on diphenols and related substances as donors - - - 0.0000000000000000000000000000000001004 141.0
HFD3_k127_335542_23 Protein of unknown function (DUF1440) K08996 - - 0.00000000000000000000009256 100.0
HFD3_k127_335542_3 Amino acid permease - - - 2.599e-200 644.0
HFD3_k127_335542_4 Beta-xylosidase K01198 - 3.2.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006627 578.0
HFD3_k127_335542_5 Putative glucoamylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 565.0
HFD3_k127_335542_6 protein histidine kinase activity K11383 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 455.0
HFD3_k127_335542_7 Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005241 440.0
HFD3_k127_335542_8 nitrite transmembrane transporter activity K02575,K10850 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 396.0
HFD3_k127_335542_9 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 372.0
HFD3_k127_344260_0 Glycosyltransferase 36 associated - - - 0.0 2660.0
HFD3_k127_344260_1 serine threonine protein kinase K12132 - 2.7.11.1 1.362e-208 682.0
HFD3_k127_344260_10 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000622 309.0
HFD3_k127_344260_11 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004223 284.0
HFD3_k127_344260_12 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000001491 245.0
HFD3_k127_344260_13 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000001022 227.0
HFD3_k127_344260_14 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000002474 220.0
HFD3_k127_344260_15 - - - - 0.0000000000000000000000000000000000000000000000000000000005718 211.0
HFD3_k127_344260_16 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000006236 208.0
HFD3_k127_344260_17 - - - - 0.000000000000000000000000000000000000000000005481 184.0
HFD3_k127_344260_18 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000004806 169.0
HFD3_k127_344260_19 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000000000000009191 162.0
HFD3_k127_344260_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 6.966e-204 654.0
HFD3_k127_344260_20 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000005533 150.0
HFD3_k127_344260_22 Transcriptional repressor, CopY family - - - 0.000000000000000000000000000000000003709 140.0
HFD3_k127_344260_23 PFAM Metal-dependent phosphohydrolase, HD - - - 0.0000000000000000000000000000000004518 139.0
HFD3_k127_344260_24 Histidine kinase - - - 0.00000000000000000000000000000005396 136.0
HFD3_k127_344260_26 Probable zinc-ribbon domain - - - 0.000000000000000000001242 98.0
HFD3_k127_344260_27 Belongs to the UPF0235 family K09131 - - 0.00000000000000001635 85.0
HFD3_k127_344260_28 PFAM D12 class N6 adenine-specific DNA methyltransferase K07318 - 2.1.1.72 0.0000000001278 72.0
HFD3_k127_344260_29 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.0000000007284 70.0
HFD3_k127_344260_3 FecR protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007712 483.0
HFD3_k127_344260_30 YGGT family K02221 - - 0.000000001158 67.0
HFD3_k127_344260_31 DnaJ molecular chaperone homology domain K19371 - - 0.000001683 61.0
HFD3_k127_344260_33 Bacterial regulatory protein, Fis family - - - 0.00005575 51.0
HFD3_k127_344260_4 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 430.0
HFD3_k127_344260_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 430.0
HFD3_k127_344260_6 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 423.0
HFD3_k127_344260_7 peptidase M20 K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009251 379.0
HFD3_k127_344260_8 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009516 319.0
HFD3_k127_344260_9 transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004329 317.0
HFD3_k127_344492_0 serine-type exopeptidase activity K01322 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.21.26 5.261e-303 945.0
HFD3_k127_344492_1 Sigma-70 region 2 K03088 - - 4.506e-226 705.0
HFD3_k127_344492_10 Amidohydrolase family K12960,K20810 - 3.5.4.28,3.5.4.31,3.5.4.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 321.0
HFD3_k127_344492_11 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004186 323.0
HFD3_k127_344492_12 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001609 263.0
HFD3_k127_344492_13 domain protein K02674,K07004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009262 289.0
HFD3_k127_344492_14 ABC-type polar amino acid transport system ATPase component K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000001239 232.0
HFD3_k127_344492_15 TonB dependent receptor K16087 - - 0.00000000000000000000000000000000000000000000000000000000000000005577 252.0
HFD3_k127_344492_16 Disulphide isomerase - - - 0.00000000000000000000000000000000000000000000000000000003106 199.0
HFD3_k127_344492_17 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000001689 175.0
HFD3_k127_344492_18 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.0000000000000000000000000000000000004317 148.0
HFD3_k127_344492_19 YCII-related domain - - - 0.00000000000000000000000000000000000385 138.0
HFD3_k127_344492_2 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006506 586.0
HFD3_k127_344492_20 YoeB-like toxin of bacterial type II toxin-antitoxin system K19158 - - 0.00000000000000000000000000000001255 130.0
HFD3_k127_344492_21 - - - - 0.00000000000000000000000000002775 123.0
HFD3_k127_344492_22 Transglycosylase SLT domain K08309 - - 0.00000000000000000000000002318 116.0
HFD3_k127_344492_23 PIN domain - - - 0.000000000000000000000002258 109.0
HFD3_k127_344492_24 Antitoxin component of a toxin-antitoxin (TA) module K19159 - - 0.00000000000000000000005354 102.0
HFD3_k127_344492_25 AraC-like ligand binding domain - - - 0.00000000000000002399 87.0
HFD3_k127_344492_26 Aspartyl protease - - - 0.00000003694 66.0
HFD3_k127_344492_27 PEP-CTERM motif - - - 0.00000003854 63.0
HFD3_k127_344492_3 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004755 578.0
HFD3_k127_344492_4 Glycosyl hydrolase family 47 K01230 - 3.2.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 544.0
HFD3_k127_344492_5 proline dipeptidase activity K01271 - 3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008535 499.0
HFD3_k127_344492_6 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 495.0
HFD3_k127_344492_7 Aminotransferase class-III K00823 - 2.6.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 488.0
HFD3_k127_344492_8 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 442.0
HFD3_k127_344492_9 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029,K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 363.0
HFD3_k127_3470986_0 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008146 452.0
HFD3_k127_3470986_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 399.0
HFD3_k127_3470986_10 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000000000007999 82.0
HFD3_k127_3470986_11 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000001069 89.0
HFD3_k127_3470986_13 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00002482 55.0
HFD3_k127_3470986_2 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000412 266.0
HFD3_k127_3470986_3 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000003743 205.0
HFD3_k127_3470986_4 PFAM Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000005307 200.0
HFD3_k127_3470986_5 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000003161 181.0
HFD3_k127_3470986_6 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000001892 160.0
HFD3_k127_3470986_7 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000000000000004624 134.0
HFD3_k127_3470986_8 - catabolite gene activator and regulatory subunit of cAMP-dependent protein K10914 - - 0.0000000000000000000000154 109.0
HFD3_k127_3470986_9 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000004637 106.0
HFD3_k127_35357_0 PFAM carbohydrate kinase K00854 - 2.7.1.17 1.491e-218 688.0
HFD3_k127_35357_1 PFAM Alcohol dehydrogenase K12957,K13979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 593.0
HFD3_k127_35357_10 - - - - 0.0000000000000000000000000000000000000000000000000000000186 208.0
HFD3_k127_35357_11 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000003191 166.0
HFD3_k127_35357_12 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000000000000000000000000000001358 155.0
HFD3_k127_35357_13 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000002652 165.0
HFD3_k127_35357_14 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.00000000000000000000000000000000000004221 147.0
HFD3_k127_35357_15 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.0000000000000000000000000001605 119.0
HFD3_k127_35357_16 iron ion binding - - - 0.000000000000000000000000493 111.0
HFD3_k127_35357_17 Tetratricopeptide repeat - - - 0.0000000002231 74.0
HFD3_k127_35357_18 Evidence 4 Homologs of previously reported genes of K03975 - - 0.000000005262 59.0
HFD3_k127_35357_19 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000007742 54.0
HFD3_k127_35357_2 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 564.0
HFD3_k127_35357_3 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000088 565.0
HFD3_k127_35357_4 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 476.0
HFD3_k127_35357_5 Glycosyl hydrolases family 43 K06113 - 3.2.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005963 368.0
HFD3_k127_35357_6 Protein of unknown function (DUF4256) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008747 322.0
HFD3_k127_35357_7 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008371 312.0
HFD3_k127_35357_8 DNA-binding transcription factor activity K02081,K02444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001305 284.0
HFD3_k127_35357_9 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000001463 222.0
HFD3_k127_35593_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 1.661e-293 913.0
HFD3_k127_35593_1 outer membrane efflux protein - - - 9.221e-196 622.0
HFD3_k127_35593_10 - - - - 0.0000000000000000003599 89.0
HFD3_k127_35593_11 amine dehydrogenase activity - - - 0.000000000000000231 91.0
HFD3_k127_35593_12 TPM domain K06872 - - 0.00000000000007856 80.0
HFD3_k127_35593_13 Predicted membrane protein (DUF2306) - - - 0.000000000009346 68.0
HFD3_k127_35593_14 Predicted membrane protein (DUF2306) - - - 0.0003134 46.0
HFD3_k127_35593_2 Peptidase inhibitor I9 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 545.0
HFD3_k127_35593_3 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006732 504.0
HFD3_k127_35593_4 PLD-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 512.0
HFD3_k127_35593_5 Transport permease protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009194 482.0
HFD3_k127_35593_6 PFAM secretion protein HlyD family protein K01993,K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 482.0
HFD3_k127_35593_7 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 475.0
HFD3_k127_3589567_0 Belongs to the DegT DnrJ EryC1 family K20429 - 2.6.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004988 558.0
HFD3_k127_3589567_1 ABC-type polysaccharide polyol phosphate transport system ATPase component K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 421.0
HFD3_k127_3589567_10 Methyltransferase type 11 Methyltransferase type 12 - - - 0.0000000000000000000000000000000000000000002509 168.0
HFD3_k127_3589567_11 Domain of unknown function (DUF5011) - - - 0.000000000000000000000000000000000000000001833 169.0
HFD3_k127_3589567_13 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000005348 101.0
HFD3_k127_3589567_14 - - - - 0.000000000000000004276 93.0
HFD3_k127_3589567_15 Fungalysin metallopeptidase (M36) - - - 0.000000000000000008261 95.0
HFD3_k127_3589567_2 ATPases associated with a variety of cellular activities K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 382.0
HFD3_k127_3589567_3 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007323 350.0
HFD3_k127_3589567_4 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 332.0
HFD3_k127_3589567_5 beta-fructofuranosidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004396 333.0
HFD3_k127_3589567_6 COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 304.0
HFD3_k127_3589567_8 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002668 269.0
HFD3_k127_3589567_9 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000000000000000000001413 206.0
HFD3_k127_3621585_0 Methionine synthase K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1118.0
HFD3_k127_3621585_1 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 353.0
HFD3_k127_3621585_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000008586 213.0
HFD3_k127_3621585_3 Gram-negative bacterial TonB protein C-terminal - - - 0.0000000005833 72.0
HFD3_k127_3647666_0 Carboxypeptidase regulatory-like domain - - - 6.165e-222 728.0
HFD3_k127_3647666_1 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 1.462e-218 689.0
HFD3_k127_3647666_10 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 415.0
HFD3_k127_3647666_11 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004186 423.0
HFD3_k127_3647666_12 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 360.0
HFD3_k127_3647666_13 PFAM Alcohol dehydrogenase K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 323.0
HFD3_k127_3647666_14 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007701 318.0
HFD3_k127_3647666_15 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 301.0
HFD3_k127_3647666_16 Formyl transferase K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000007712 245.0
HFD3_k127_3647666_17 Glycosyltransferase like family 2 K16870 - 2.4.1.289 0.00000000000000000000000000000000000000000000000000000000000000000004135 246.0
HFD3_k127_3647666_18 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000007058 209.0
HFD3_k127_3647666_19 methyltransferase K05928 - 2.1.1.95 0.0000000000000000000000000000000000000000000000000000000008849 211.0
HFD3_k127_3647666_2 Dehydrogenase K02030,K03810 - - 1.023e-208 671.0
HFD3_k127_3647666_20 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000001308 188.0
HFD3_k127_3647666_21 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000003612 170.0
HFD3_k127_3647666_22 RDD family - - - 0.000000000000000000000000000000000000000001524 167.0
HFD3_k127_3647666_23 chlorophyll binding - - - 0.000000000000000000000000000000000001698 151.0
HFD3_k127_3647666_24 Aspartyl protease - - - 0.00000000000000000000000000000000028 140.0
HFD3_k127_3647666_25 PFAM von Willebrand factor type A - - - 0.000000000000000000002302 107.0
HFD3_k127_3647666_26 cheY-homologous receiver domain - - - 0.0000000000000000003965 94.0
HFD3_k127_3647666_27 Cytochrome c K00406,K08906 - - 0.000000000002581 72.0
HFD3_k127_3647666_28 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000003719 72.0
HFD3_k127_3647666_29 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000001796 67.0
HFD3_k127_3647666_3 Glutamine amidotransferases class-II K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 562.0
HFD3_k127_3647666_4 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 548.0
HFD3_k127_3647666_5 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005378 489.0
HFD3_k127_3647666_6 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 484.0
HFD3_k127_3647666_7 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006059 475.0
HFD3_k127_3647666_8 Transketolase, pyrimidine binding domain K00167 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 436.0
HFD3_k127_3647666_9 e3 binding domain K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 428.0
HFD3_k127_3763459_0 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 616.0
HFD3_k127_3763459_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006524 589.0
HFD3_k127_3763459_10 Heat shock chaperonin-binding motif. K09553 - - 0.0005338 52.0
HFD3_k127_3763459_2 tRNA processing K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 293.0
HFD3_k127_3763459_3 Protein of unknown function (DUF1003) - - - 0.000000000000000000000000000000000000000000000000000000000002441 219.0
HFD3_k127_3763459_4 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000005634 208.0
HFD3_k127_3763459_5 HAD-superfamily hydrolase subfamily IA, variant 3 K01091,K01838 - 3.1.3.18,5.4.2.6 0.000000000000000000000000000000003634 137.0
HFD3_k127_3763459_6 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000008631 93.0
HFD3_k127_3763459_7 histone H2A K63-linked ubiquitination - - - 0.0000000000002878 77.0
HFD3_k127_3763459_8 PFAM Tetratricopeptide repeat - - - 0.000000000003897 79.0
HFD3_k127_3763459_9 Concanavalin A-like lectin/glucanases superfamily - - - 0.000082 56.0
HFD3_k127_376583_0 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 396.0
HFD3_k127_376583_1 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009728 370.0
HFD3_k127_376583_2 Peptidase family M48 - - - 0.000000000000000000000002735 117.0
HFD3_k127_3770253_0 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002441 282.0
HFD3_k127_3770253_1 Protein of unknown function with PCYCGC motif - - - 0.00000000000000000006483 96.0
HFD3_k127_3770253_3 NnrS protein - - - 0.00000000000000004417 84.0
HFD3_k127_3770253_4 Peptidase M16 inactive domain - - - 0.000000000169 72.0
HFD3_k127_3803318_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 2.992e-310 991.0
HFD3_k127_3803318_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 319.0
HFD3_k127_3803318_2 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000001205 258.0
HFD3_k127_3803318_3 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000000002032 184.0
HFD3_k127_3803318_4 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.000000000000000000000000000000000000854 153.0
HFD3_k127_3803318_5 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000993 134.0
HFD3_k127_3803318_6 ErfK YbiS YcfS YnhG - - - 0.000000000000009319 87.0
HFD3_k127_3886409_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.0 1320.0
HFD3_k127_3886409_1 helicase activity - - - 0.0 1021.0
HFD3_k127_3886409_10 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 285.0
HFD3_k127_3886409_11 transmembrane transport K02025,K15771 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004023 282.0
HFD3_k127_3886409_12 enzyme related to lactoylglutathione lyase K06996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003149 273.0
HFD3_k127_3886409_13 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009382 256.0
HFD3_k127_3886409_14 - - - - 0.000000000000000000000000000000000000000000000000000000000004841 216.0
HFD3_k127_3886409_15 EamA-like transporter family K07790 - - 0.0000000000000000000000000000000000000000000000000008113 194.0
HFD3_k127_3886409_16 recA bacterial DNA recombination protein - - - 0.000000000000000000000000000000000000000000000000002815 191.0
HFD3_k127_3886409_17 PFAM Histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000000000000000000000005495 184.0
HFD3_k127_3886409_18 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000007922 188.0
HFD3_k127_3886409_19 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000003142 169.0
HFD3_k127_3886409_2 PFAM Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 1.707e-195 621.0
HFD3_k127_3886409_20 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000003879 137.0
HFD3_k127_3886409_21 cAMP biosynthetic process - - - 0.00000000000000000000005227 115.0
HFD3_k127_3886409_22 Domain of unknown function (DUF4440) - - - 0.0000000000000000005462 92.0
HFD3_k127_3886409_23 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02667 - - 0.000000000000243 78.0
HFD3_k127_3886409_24 - - - - 0.000008338 49.0
HFD3_k127_3886409_3 DNA polymerase beta thumb K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009846 541.0
HFD3_k127_3886409_4 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 475.0
HFD3_k127_3886409_5 PFAM Beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 463.0
HFD3_k127_3886409_6 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 403.0
HFD3_k127_3886409_7 Belongs to the ABC transporter superfamily K02010,K10112 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007961 383.0
HFD3_k127_3886409_8 glycerophosphodiester transmembrane transport K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008623 306.0
HFD3_k127_3886409_9 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K14161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 308.0
HFD3_k127_3889813_0 Serine aminopeptidase, S33 K00433 - 1.11.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 494.0
HFD3_k127_3889813_1 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 423.0
HFD3_k127_3889813_2 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 366.0
HFD3_k127_3889813_3 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 324.0
HFD3_k127_3889813_4 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 315.0
HFD3_k127_3889813_5 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 314.0
HFD3_k127_3889813_6 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000003962 237.0
HFD3_k127_3889813_7 PFAM Cupin 2 conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000003397 186.0
HFD3_k127_3889813_8 Pfam Zn-finger in ubiquitin-hydrolases and other protein K03455 - - 0.0000000000000000000000000000000000000002689 151.0
HFD3_k127_3889813_9 cheY-homologous receiver domain - - - 0.0000000000000000000000000000003545 127.0
HFD3_k127_3909924_0 choline dehydrogenase activity - - - 1.379e-262 816.0
HFD3_k127_3909924_1 gluconolactonase activity K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006783 597.0
HFD3_k127_3909924_2 Pyridine nucleotide-disulphide oxidoreductase K03885,K10716 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006899 587.0
HFD3_k127_3909924_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 454.0
HFD3_k127_3909924_4 lipopolysaccharide transport K22110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004592 384.0
HFD3_k127_3909924_5 Cupin 2, conserved barrel domain protein K11477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004462 347.0
HFD3_k127_3909924_6 Transglutaminase-like superfamily - - - 0.0000000000647 78.0
HFD3_k127_3926739_0 Succinyl-CoA ligase like flavodoxin domain - - - 1.954e-320 1006.0
HFD3_k127_3926739_1 glutamate--cysteine ligase - - - 1.676e-235 744.0
HFD3_k127_3926739_10 pectinesterase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000004872 243.0
HFD3_k127_3926739_11 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000006065 209.0
HFD3_k127_3926739_12 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000001302 210.0
HFD3_k127_3926739_13 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.00000000000000000000000000000000000000000000000000008336 204.0
HFD3_k127_3926739_15 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000008323 145.0
HFD3_k127_3926739_16 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000006181 151.0
HFD3_k127_3926739_18 Universal stress protein family - - - 0.0000000000000000000000000000000002972 143.0
HFD3_k127_3926739_19 Universal stress protein family - - - 0.0000000000000000000000000000001221 129.0
HFD3_k127_3926739_2 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 1.14e-223 708.0
HFD3_k127_3926739_20 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000007518 118.0
HFD3_k127_3926739_21 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000007884 108.0
HFD3_k127_3926739_22 oxidoreductase activity, acting on diphenols and related substances as donors - - - 0.0000000000000000000000271 105.0
HFD3_k127_3926739_23 AMP binding - - - 0.000000000000000159 90.0
HFD3_k127_3926739_24 Prokaryotic dksA/traR C4-type zinc finger - - - 0.000000005534 65.0
HFD3_k127_3926739_25 - - - - 0.00000002801 60.0
HFD3_k127_3926739_3 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 621.0
HFD3_k127_3926739_4 ABC1 family K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 599.0
HFD3_k127_3926739_5 Zinc-binding dehydrogenase K00008,K00148,K18369 - 1.1.1.14,1.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 575.0
HFD3_k127_3926739_6 Domains REC, sigma54 interaction, HTH8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 449.0
HFD3_k127_3926739_7 Zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 414.0
HFD3_k127_3926739_8 Putative neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 302.0
HFD3_k127_3926739_9 Protein of unknown function (DUF1003) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002938 267.0
HFD3_k127_3964275_0 - - - - 0.0 1959.0
HFD3_k127_3964275_1 - - - - 0.0 1734.0
HFD3_k127_3964275_10 pentaerythritol trinitrate reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 581.0
HFD3_k127_3964275_11 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004547 565.0
HFD3_k127_3964275_12 Major Facilitator Superfamily K08191 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006654 559.0
HFD3_k127_3964275_13 Domain of unknown function (DUF5107) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007686 528.0
HFD3_k127_3964275_14 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009322 492.0
HFD3_k127_3964275_15 Pectate lyase K01728,K21606 - 3.2.1.202,4.2.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 492.0
HFD3_k127_3964275_16 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 442.0
HFD3_k127_3964275_17 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 434.0
HFD3_k127_3964275_18 dihydroorotate dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 424.0
HFD3_k127_3964275_19 activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation K08282,K13419 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 421.0
HFD3_k127_3964275_2 Alpha-L-rhamnosidase N-terminal domain K05989 - 3.2.1.40 0.0 1221.0
HFD3_k127_3964275_20 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 368.0
HFD3_k127_3964275_21 PFAM Sugar isomerase (SIS) K02082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 362.0
HFD3_k127_3964275_22 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 362.0
HFD3_k127_3964275_23 dioxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 335.0
HFD3_k127_3964275_24 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.2.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 320.0
HFD3_k127_3964275_25 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K02564 - 3.5.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 302.0
HFD3_k127_3964275_26 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002777 287.0
HFD3_k127_3964275_27 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001964 284.0
HFD3_k127_3964275_28 DeoR C terminal sensor domain K02081 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001957 279.0
HFD3_k127_3964275_29 Dihydrodipicolinate synthetase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004332 279.0
HFD3_k127_3964275_3 siderophore transport K02014 - - 0.0 1199.0
HFD3_k127_3964275_30 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K02564 - 3.5.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000101 268.0
HFD3_k127_3964275_31 Sodium:solute symporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001638 284.0
HFD3_k127_3964275_32 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000002278 273.0
HFD3_k127_3964275_33 beta-galactosidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000334 278.0
HFD3_k127_3964275_34 Domain of unknown function (DUF4091) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006493 260.0
HFD3_k127_3964275_35 ROK family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002116 250.0
HFD3_k127_3964275_36 PFAM ketose-bisphosphate aldolase, class-II K08302 - 4.1.2.40 0.00000000000000000000000000000000000000000000000000000000000000000005483 241.0
HFD3_k127_3964275_37 Phosphomethylpyrimidine kinase K00882 - 2.7.1.56 0.0000000000000000000000000000000000000000000000000000000000000462 225.0
HFD3_k127_3964275_38 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000004464 211.0
HFD3_k127_3964275_39 Xylose isomerase - - - 0.000000000000000000000000000000000000000000000000000007448 200.0
HFD3_k127_3964275_4 choline dehydrogenase activity - - - 3.823e-237 743.0
HFD3_k127_3964275_40 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000002334 186.0
HFD3_k127_3964275_41 Domain of unknown function (DUF4962) K19051 GO:0003674,GO:0003824,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006082,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008201,GO:0009056,GO:0009057,GO:0009987,GO:0016829,GO:0016835,GO:0016837,GO:0030202,GO:0030203,GO:0030211,GO:0042597,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044248,GO:0044273,GO:0044281,GO:0044464,GO:0047488,GO:0071704,GO:0097367,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1901681,GO:1903510 4.2.2.7,4.2.2.8 0.00000000000000000000000000000000000000000000002064 195.0
HFD3_k127_3964275_42 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000929 166.0
HFD3_k127_3964275_43 Galactokinase 2 K18674 GO:0003674,GO:0003824,GO:0004335,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006012,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019318,GO:0031982,GO:0043226,GO:0043227,GO:0043230,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044421,GO:0044424,GO:0044464,GO:0046835,GO:0070062,GO:0071704,GO:1903561 2.7.1.157 0.000000000000000000000000000000000003841 158.0
HFD3_k127_3964275_44 xylan catabolic process - - - 0.00000000000000000000000000000000005491 143.0
HFD3_k127_3964275_45 Transposase K07497 - - 0.000000000000000000000000000000001241 132.0
HFD3_k127_3964275_46 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000003316 123.0
HFD3_k127_3964275_47 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000005177 102.0
HFD3_k127_3964275_48 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000002151 83.0
HFD3_k127_3964275_49 Oxidoreductase family, C-terminal alpha/beta domain K13020 - 1.1.1.335 0.00000000000005652 83.0
HFD3_k127_3964275_5 Amino acid permease K03294,K19540 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039 - 3.119e-214 674.0
HFD3_k127_3964275_50 Histidine kinase - - - 0.00000000000008181 74.0
HFD3_k127_3964275_51 DNA ligase K01971 - 6.5.1.1 0.0000000000005561 73.0
HFD3_k127_3964275_52 Gluconate 2-dehydrogenase subunit 3 K06152 - 1.1.99.3 0.0000000005318 65.0
HFD3_k127_3964275_53 PFAM Integrase catalytic region K07497 - - 0.000000005175 60.0
HFD3_k127_3964275_54 Integrase core domain K07497 - - 0.00000001257 60.0
HFD3_k127_3964275_55 Phage integrase, N-terminal SAM-like domain K14059 - - 0.0000004685 54.0
HFD3_k127_3964275_56 Iron-containing redox enzyme - - - 0.0000004965 54.0
HFD3_k127_3964275_57 alginic acid biosynthetic process - - - 0.00001143 58.0
HFD3_k127_3964275_58 Cupin 2, conserved barrel - - - 0.00004649 48.0
HFD3_k127_3964275_59 GDSL-like Lipase/Acylhydrolase - - - 0.0003623 53.0
HFD3_k127_3964275_6 Sodium:solute symporter family - - - 7.434e-205 649.0
HFD3_k127_3964275_61 transposition K07497 - - 0.0009153 44.0
HFD3_k127_3964275_7 dipeptidyl-peptidase activity K06978 - - 5.482e-194 625.0
HFD3_k127_3964275_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008047 612.0
HFD3_k127_3964275_9 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 593.0
HFD3_k127_3975177_0 - K17285 - - 0.0 1258.0
HFD3_k127_3975177_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 3.223e-249 797.0
HFD3_k127_3975177_10 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 384.0
HFD3_k127_3975177_11 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 362.0
HFD3_k127_3975177_12 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009006 376.0
HFD3_k127_3975177_13 Haem-degrading - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 370.0
HFD3_k127_3975177_14 ABC-type polysaccharide polyol phosphate transport system ATPase component K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 336.0
HFD3_k127_3975177_15 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 321.0
HFD3_k127_3975177_16 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008217 292.0
HFD3_k127_3975177_17 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001092 277.0
HFD3_k127_3975177_18 Glycosyl transferase family 4 K02851 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000003629 269.0
HFD3_k127_3975177_19 TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008511 257.0
HFD3_k127_3975177_2 Carbamoyltransferase C-terminus K00612 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000748 611.0
HFD3_k127_3975177_20 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001327 249.0
HFD3_k127_3975177_21 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000009809 200.0
HFD3_k127_3975177_22 Tellurite resistance protein TehB K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000008482 191.0
HFD3_k127_3975177_23 O-Antigen ligase K02847 - - 0.00000000000000000000000000000002274 141.0
HFD3_k127_3975177_24 3-demethylubiquinone-9 3-O-methyltransferase activity K15257 - - 0.0000000000000000000000000005849 124.0
HFD3_k127_3975177_25 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000006482 123.0
HFD3_k127_3975177_26 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000001111 95.0
HFD3_k127_3975177_27 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000000000001367 97.0
HFD3_k127_3975177_28 PD-(D/E)XK nuclease superfamily - - - 0.000000000009522 69.0
HFD3_k127_3975177_29 heat shock protein binding - - - 0.0000000004297 70.0
HFD3_k127_3975177_3 ADP-glyceromanno-heptose 6-epimerase activity K01710,K01784,K08678,K08679 - 4.1.1.35,4.2.1.46,5.1.3.2,5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 515.0
HFD3_k127_3975177_30 Glycosyl transferases group 1 - - - 0.0000000008367 70.0
HFD3_k127_3975177_31 Glycosyltransferase like family 2 K07011,K20444 - - 0.00000001786 66.0
HFD3_k127_3975177_32 peptidyl-tyrosine sulfation - - - 0.0000001149 64.0
HFD3_k127_3975177_33 heat shock protein binding - - - 0.0000004561 61.0
HFD3_k127_3975177_34 lipolytic protein G-D-S-L family K19172 GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016020,GO:0016051,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.000008563 57.0
HFD3_k127_3975177_35 Protein of unknown function (DUF465) - - - 0.00004733 48.0
HFD3_k127_3975177_4 ADP-glyceromanno-heptose 6-epimerase activity K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 510.0
HFD3_k127_3975177_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 528.0
HFD3_k127_3975177_6 asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004452 450.0
HFD3_k127_3975177_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 411.0
HFD3_k127_3975177_8 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 406.0
HFD3_k127_3975177_9 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007521 384.0
HFD3_k127_4023402_0 Glycogen debranching enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 558.0
HFD3_k127_4023402_1 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004849 352.0
HFD3_k127_4023402_2 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 298.0
HFD3_k127_4023402_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009425 268.0
HFD3_k127_4023402_4 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000009359 252.0
HFD3_k127_4023402_5 Putative stress-induced transcription regulator - - - 0.0000000000000000000000000000000000000000003074 166.0
HFD3_k127_4023402_6 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000002696 128.0
HFD3_k127_4023402_7 MASE1 - - - 0.0000000000000000000001312 113.0
HFD3_k127_4023402_8 Mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.0000000001283 66.0
HFD3_k127_4048432_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006953 604.0
HFD3_k127_4048432_1 COG3209 Rhs family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 359.0
HFD3_k127_4048432_2 Plasmid stabilization system K19092 - - 0.0000000000000000000000000000000000000000003359 160.0
HFD3_k127_4048432_3 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000000000000000141 110.0
HFD3_k127_4105175_0 MatE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 603.0
HFD3_k127_4105175_1 Bacterial regulatory protein, Fis family K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007231 556.0
HFD3_k127_4105175_10 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K04750 - - 0.00000000000000000000000000000000001798 138.0
HFD3_k127_4105175_11 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000009837 121.0
HFD3_k127_4105175_12 PEP-CTERM motif - - - 0.0000006241 59.0
HFD3_k127_4105175_2 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 477.0
HFD3_k127_4105175_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 479.0
HFD3_k127_4105175_4 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 344.0
HFD3_k127_4105175_5 PAS domain containing protein K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 336.0
HFD3_k127_4105175_6 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003636 276.0
HFD3_k127_4105175_7 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001269 258.0
HFD3_k127_4105175_8 phosphoserine phosphatase activity K07315,K16928 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000001639 215.0
HFD3_k127_4105175_9 mannose-6-phosphate isomerase K01809,K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000003258 152.0
HFD3_k127_4119313_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 3.079e-312 984.0
HFD3_k127_4119313_1 two component, sigma54 specific, transcriptional regulator, Fis family K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000533 329.0
HFD3_k127_4119313_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000412 230.0
HFD3_k127_4119313_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000003773 132.0
HFD3_k127_4119313_4 WD40-like Beta Propeller Repeat - - - 0.00000003183 56.0
HFD3_k127_4119313_5 general stress protein - - - 0.0000004926 57.0
HFD3_k127_4126721_0 radical SAM domain protein - - - 4.498e-288 894.0
HFD3_k127_4126721_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008629 622.0
HFD3_k127_4126721_10 PFAM Endonuclease Exonuclease phosphatase - - - 0.000000000002514 77.0
HFD3_k127_4126721_2 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 461.0
HFD3_k127_4126721_3 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 298.0
HFD3_k127_4126721_4 oxidation-reduction process K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000003135 164.0
HFD3_k127_4126721_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000000000000000000000000000000000001405 169.0
HFD3_k127_4126721_7 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000005837 135.0
HFD3_k127_4126721_8 peptidase inhibitor activity - - - 0.000000000000000000000000007021 123.0
HFD3_k127_4126721_9 - - - - 0.0000000000000000005992 96.0
HFD3_k127_412694_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.0 1717.0
HFD3_k127_412694_1 protein secretion by the type I secretion system K11085 - - 8.258e-264 824.0
HFD3_k127_412694_2 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 336.0
HFD3_k127_412694_3 - - - - 0.000000000000000000000000000000000000000000000000001406 190.0
HFD3_k127_412694_4 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000001088 145.0
HFD3_k127_412694_5 - - - - 0.00000000000000000000000000000001306 132.0
HFD3_k127_412694_6 Beta/gamma crystallins - - - 0.0001465 48.0
HFD3_k127_4130073_0 Carbamoyltransferase C-terminus K00612 - - 4.221e-262 820.0
HFD3_k127_4130073_1 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004661 492.0
HFD3_k127_4130073_10 - - - - 0.0000000000002135 74.0
HFD3_k127_4130073_11 nodulation - - - 0.0000000002941 66.0
HFD3_k127_4130073_2 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 427.0
HFD3_k127_4130073_3 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 359.0
HFD3_k127_4130073_4 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008409 297.0
HFD3_k127_4130073_5 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004261 275.0
HFD3_k127_4130073_6 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000005861 194.0
HFD3_k127_4130073_7 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000002207 181.0
HFD3_k127_4130073_8 PFAM glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000007348 152.0
HFD3_k127_4130073_9 Polysaccharide biosynthesis protein K17947 - 5.1.3.25 0.000000000000000000000000005843 112.0
HFD3_k127_4186782_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 2.012e-290 913.0
HFD3_k127_4186782_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 617.0
HFD3_k127_4186782_10 Oxidoreductase, molybdopterin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009673 287.0
HFD3_k127_4186782_11 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000004366 246.0
HFD3_k127_4186782_12 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001265 241.0
HFD3_k127_4186782_13 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000001247 227.0
HFD3_k127_4186782_14 TIGRFAM geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000000000000006786 205.0
HFD3_k127_4186782_15 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000004265 172.0
HFD3_k127_4186782_16 DSBA-like thioredoxin domain K21990 - - 0.0000000000000000000000000000000000002183 151.0
HFD3_k127_4186782_17 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000001276 100.0
HFD3_k127_4186782_18 Thioesterase superfamily K07107 - - 0.0000000000000000000002188 102.0
HFD3_k127_4186782_19 Domain of unknown function (DUF4870) - - - 0.000000000000000000004166 98.0
HFD3_k127_4186782_2 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 588.0
HFD3_k127_4186782_20 Carboxypeptidase regulatory-like domain - - - 0.0000000000004835 82.0
HFD3_k127_4186782_21 Vitamin k epoxide reductase K00368 - 1.7.2.1 0.000009414 53.0
HFD3_k127_4186782_22 Protein of unknown function (DUF4019) - - - 0.0004918 50.0
HFD3_k127_4186782_3 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 533.0
HFD3_k127_4186782_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004529 477.0
HFD3_k127_4186782_5 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 456.0
HFD3_k127_4186782_6 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 380.0
HFD3_k127_4186782_7 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 359.0
HFD3_k127_4186782_8 AMMECR1 K06990,K09141 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007309 344.0
HFD3_k127_4186782_9 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 326.0
HFD3_k127_4191261_0 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001103 254.0
HFD3_k127_4191261_1 Galactose oxidase, central domain - - - 0.0000000000000000000000000000000000003268 162.0
HFD3_k127_4191261_2 Leucine-rich repeat (LRR) protein - - - 0.00000000000000000000009995 115.0
HFD3_k127_4191261_3 Sigma-54 interaction domain K07714 - - 0.000000000005704 72.0
HFD3_k127_4191261_4 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02396,K02397 - - 0.000000001068 71.0
HFD3_k127_4191261_5 domain protein - - - 0.0000000584 66.0
HFD3_k127_4198475_0 Multicopper oxidase - - - 0.0 1723.0
HFD3_k127_4198475_1 alpha-L-arabinofuranosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 590.0
HFD3_k127_4198475_10 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 402.0
HFD3_k127_4198475_11 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006319 369.0
HFD3_k127_4198475_12 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006806 372.0
HFD3_k127_4198475_13 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 GO:0000166,GO:0003674,GO:0003824,GO:0004152,GO:0004158,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0016020,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0032553,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 332.0
HFD3_k127_4198475_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 312.0
HFD3_k127_4198475_15 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007749 283.0
HFD3_k127_4198475_16 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000002819 228.0
HFD3_k127_4198475_17 SCO1/SenC K07152,K08976 - - 0.000000000000000000000000000000000000000000000000000000000001082 220.0
HFD3_k127_4198475_18 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000001453 207.0
HFD3_k127_4198475_19 SCO1/SenC K07152,K08976 - - 0.00000000000000000000000000000000000000000000000000004678 198.0
HFD3_k127_4198475_2 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 556.0
HFD3_k127_4198475_20 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000005455 182.0
HFD3_k127_4198475_21 Glycosyl transferase, family 2 K07011 - - 0.000000000000000000000000000000000000000000002687 176.0
HFD3_k127_4198475_22 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000001272 166.0
HFD3_k127_4198475_23 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000005308 156.0
HFD3_k127_4198475_24 PFAM Iron permease FTR1 - - - 0.00000000000000000007369 100.0
HFD3_k127_4198475_25 PFAM response regulator receiver - - - 0.000000000000001748 81.0
HFD3_k127_4198475_26 Protein of unknown function (DUF1176) - - - 0.00000000000001019 84.0
HFD3_k127_4198475_27 Protein conserved in bacteria K09914 - - 0.000000000009467 75.0
HFD3_k127_4198475_28 Protein of unknown function (DUF3108) - - - 0.0000004001 63.0
HFD3_k127_4198475_29 translation initiation factor activity K08086,K20541 - - 0.000001221 61.0
HFD3_k127_4198475_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 473.0
HFD3_k127_4198475_30 Trypsin-like peptidase domain K01173 - - 0.00001123 56.0
HFD3_k127_4198475_4 Belongs to the aldehyde dehydrogenase family K22187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005668 461.0
HFD3_k127_4198475_5 dioxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 428.0
HFD3_k127_4198475_6 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 425.0
HFD3_k127_4198475_7 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 415.0
HFD3_k127_4198475_8 AMP-binding enzyme C-terminal domain K00666,K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008541 420.0
HFD3_k127_4198475_9 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 401.0
HFD3_k127_4220518_0 domain protein - - - 0.0 1103.0
HFD3_k127_4220518_1 Dienelactone hydrolase family - - - 1.787e-320 994.0
HFD3_k127_4220518_10 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004747 421.0
HFD3_k127_4220518_11 Lactonase, 7-bladed beta-propeller K07404 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 404.0
HFD3_k127_4220518_12 Putative serine dehydratase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 401.0
HFD3_k127_4220518_13 Heparinase II/III N-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 394.0
HFD3_k127_4220518_14 Aspartyl protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 373.0
HFD3_k127_4220518_15 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 372.0
HFD3_k127_4220518_16 Phosphoenolpyruvate phosphomutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 356.0
HFD3_k127_4220518_17 PFAM Glycosyl transferases group 1 K12995 - 2.4.1.348 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008763 356.0
HFD3_k127_4220518_18 Glycosyltransferase family 28 C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 350.0
HFD3_k127_4220518_19 regulation of single-species biofilm formation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 320.0
HFD3_k127_4220518_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 2.519e-286 896.0
HFD3_k127_4220518_20 YdjC-like protein K03478 - 3.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 293.0
HFD3_k127_4220518_21 Glycosyltransferase family 28 C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007482 297.0
HFD3_k127_4220518_22 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001872 289.0
HFD3_k127_4220518_23 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000002519 214.0
HFD3_k127_4220518_24 TIGRFAM VWFA-related Acidobacterial domain - - - 0.0000000000000000000000000000000000000000000000001057 201.0
HFD3_k127_4220518_25 PFAM OsmC family protein K04063 - - 0.00000000000000000000000000000000000000000000002974 174.0
HFD3_k127_4220518_26 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000001518 182.0
HFD3_k127_4220518_27 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000005164 168.0
HFD3_k127_4220518_28 helix_turn_helix multiple antibiotic resistance protein K15973 - - 0.0000000000000000000000000000000000000001452 155.0
HFD3_k127_4220518_29 - - - - 0.000000000000000000000000000000000000002166 149.0
HFD3_k127_4220518_3 Belongs to the glycosyl hydrolase 30 family K01201 - 3.2.1.45 3.184e-220 692.0
HFD3_k127_4220518_30 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000002295 153.0
HFD3_k127_4220518_31 Capsule assembly protein Wzi - - - 0.0000000000000000000000000000000000000046 158.0
HFD3_k127_4220518_32 - - - - 0.00000000000000000000000000000000000001693 148.0
HFD3_k127_4220518_33 DinB superfamily K07552 - - 0.000000000000000000000000000000000003519 143.0
HFD3_k127_4220518_34 hydroperoxide reductase activity K01607 - 4.1.1.44 0.000000000000000000000000000000000704 132.0
HFD3_k127_4220518_35 - - - - 0.00000000000000000000006199 104.0
HFD3_k127_4220518_36 Pilus assembly protein PilX K02673 - - 0.000000000000000000945 99.0
HFD3_k127_4220518_4 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 606.0
HFD3_k127_4220518_40 Choline/ethanolamine kinase - - - 0.00008421 55.0
HFD3_k127_4220518_41 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.0002916 46.0
HFD3_k127_4220518_42 type IV pilus modification protein PilV K02671 - - 0.0009765 48.0
HFD3_k127_4220518_5 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 568.0
HFD3_k127_4220518_6 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 472.0
HFD3_k127_4220518_7 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006295 451.0
HFD3_k127_4220518_8 Pirin C-terminal cupin domain K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 431.0
HFD3_k127_4220518_9 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 419.0
HFD3_k127_4230520_0 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 0.0 1290.0
HFD3_k127_4230520_1 PFAM Glycoside hydrolase, family 2, TIM barrel K01190 - 3.2.1.23 8.43e-311 969.0
HFD3_k127_4230520_2 Domain of unknown function (DUF4982) K01190 - 3.2.1.23 6.12e-276 871.0
HFD3_k127_4230520_3 Sialate O-acetylesterase K05970 - 3.1.1.53 4.919e-196 623.0
HFD3_k127_4230520_4 PFAM Glycosyl Hydrolase Family 88 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 434.0
HFD3_k127_4230520_5 endo-1,4-beta-xylanase activity K21606 - 3.2.1.202 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009182 367.0
HFD3_k127_4230520_6 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004375 336.0
HFD3_k127_4230520_7 - - - - 0.000000000000000000000000000000000000000000007684 167.0
HFD3_k127_4237469_0 Belongs to the 5'-nucleotidase family K11751 - 3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 529.0
HFD3_k127_4237469_1 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009228 278.0
HFD3_k127_4237469_10 Domain of unknown function (DUF4112) - - - 0.000000000000000000000000001716 117.0
HFD3_k127_4237469_11 Polymer-forming cytoskeletal - - - 0.00000000000000001674 92.0
HFD3_k127_4237469_2 Male sterility protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004991 259.0
HFD3_k127_4237469_3 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000009408 207.0
HFD3_k127_4237469_4 - K07018 - - 0.0000000000000000000000000000000000000000000001758 173.0
HFD3_k127_4237469_5 AhpC/TSA family - - - 0.0000000000000000000000000000000000000000000004495 170.0
HFD3_k127_4237469_6 PFAM peptidase M1, membrane alanine aminopeptidase - - - 0.00000000000000000000000000000000000000000000465 185.0
HFD3_k127_4237469_7 photosynthesis - - - 0.000000000000000000000000000000000000000001905 162.0
HFD3_k127_4237469_8 Belongs to the Fur family K09825 - - 0.0000000000000000000000000000002523 127.0
HFD3_k127_4237469_9 Thioesterase superfamily K10806 - - 0.00000000000000000000000000001461 122.0
HFD3_k127_4238292_0 serine-type peptidase activity - - - 0.0 1094.0
HFD3_k127_4238292_1 hydrolase family 92 - - - 3.686e-302 955.0
HFD3_k127_4238292_10 L-seryl-tRNA selenium transferase K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 391.0
HFD3_k127_4238292_11 Pyridoxal-phosphate dependent enzyme K12339 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006586 370.0
HFD3_k127_4238292_12 Cys Met metabolism K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 362.0
HFD3_k127_4238292_13 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 297.0
HFD3_k127_4238292_14 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004883 286.0
HFD3_k127_4238292_15 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001185 271.0
HFD3_k127_4238292_16 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000006378 267.0
HFD3_k127_4238292_17 LytTr DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003223 252.0
HFD3_k127_4238292_18 Belongs to the BI1 family K06890,K19416 - - 0.000000000000000000000000000000000000000000000000000001123 200.0
HFD3_k127_4238292_19 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000009816 194.0
HFD3_k127_4238292_2 ThiS family K21029,K21147 - 2.7.7.80,2.8.1.11 9.258e-197 624.0
HFD3_k127_4238292_20 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000003152 201.0
HFD3_k127_4238292_21 JAB/MPN domain - - - 0.000000000000000000000000000000000000003264 154.0
HFD3_k127_4238292_22 Peptidase family M23 - - - 0.00000000000000000000000000000000000008522 154.0
HFD3_k127_4238292_23 SET domain K07117 - - 0.0000000000000000000000000000000499 129.0
HFD3_k127_4238292_24 - - - - 0.00000000000000000000000000001018 126.0
HFD3_k127_4238292_25 Predicted membrane protein (DUF2085) - - - 0.000000000000000000000000005064 118.0
HFD3_k127_4238292_26 Cold-Shock Protein K03704 - - 0.000000000000000000000006182 105.0
HFD3_k127_4238292_27 - - - - 0.00000000000000001698 91.0
HFD3_k127_4238292_28 Transcriptional regulator, AraC family K18991 - - 0.00000000000000697 79.0
HFD3_k127_4238292_3 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 580.0
HFD3_k127_4238292_30 protein conserved in cyanobacteria - - - 0.0000000135 62.0
HFD3_k127_4238292_4 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 532.0
HFD3_k127_4238292_5 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008672 505.0
HFD3_k127_4238292_6 Peptidase family M3 K01284 - 3.4.15.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 484.0
HFD3_k127_4238292_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 415.0
HFD3_k127_4238292_8 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004513 415.0
HFD3_k127_4238292_9 peptidase S8 and S53, subtilisin, kexin, sedolisin K20754 - 3.4.21.111 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 411.0
HFD3_k127_4241575_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 612.0
HFD3_k127_4241575_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 576.0
HFD3_k127_4241575_10 lipopolysaccharide heptosyltransferase K02841,K02843 - - 0.0000000000000000000000000000002601 136.0
HFD3_k127_4241575_11 YbbR-like protein - - - 0.00000000000000000003642 102.0
HFD3_k127_4241575_12 domain protein - - - 0.00000000000000005449 95.0
HFD3_k127_4241575_13 domain protein K14194 - - 0.000000000005806 79.0
HFD3_k127_4241575_14 phosphorelay signal transduction system - - - 0.000000001376 64.0
HFD3_k127_4241575_15 self proteolysis - - - 0.00002351 56.0
HFD3_k127_4241575_2 Transporter-associated region K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 442.0
HFD3_k127_4241575_3 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 413.0
HFD3_k127_4241575_4 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001729 295.0
HFD3_k127_4241575_5 Actin K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001381 261.0
HFD3_k127_4241575_6 TIGRFAM cation diffusion facilitator family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000001679 241.0
HFD3_k127_4241575_7 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000008837 214.0
HFD3_k127_4241575_8 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000001436 197.0
HFD3_k127_4241575_9 CarD-like/TRCF domain K07736 - - 0.00000000000000000000000000000000000001708 150.0
HFD3_k127_4297920_0 Tricorn protease homolog K08676 - - 0.0 1499.0
HFD3_k127_4297920_1 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009296 608.0
HFD3_k127_4297920_10 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000005774 239.0
HFD3_k127_4297920_11 Enoyl-CoA hydratase/isomerase K01715,K13767 GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000001827 230.0
HFD3_k127_4297920_12 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000003005 203.0
HFD3_k127_4297920_13 transferase activity, transferring glycosyl groups K07011 - - 0.00000000000000000000000000000000000000000000000000001437 204.0
HFD3_k127_4297920_14 Protein of unknown function (DUF2911) - - - 0.00000000000000000000000000000000000000000000000005964 190.0
HFD3_k127_4297920_15 DinB family - - - 0.0000000000000000000000000000000000000000000002212 172.0
HFD3_k127_4297920_16 PFAM MgtC SapB transporter K07507 - - 0.000000000000000000000000000000000000000000004611 168.0
HFD3_k127_4297920_17 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000009561 165.0
HFD3_k127_4297920_18 Uncharacterized conserved protein (DUF2277) - - - 0.000000000000000000000000000000000001439 141.0
HFD3_k127_4297920_19 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000006213 141.0
HFD3_k127_4297920_2 Peptidase M61 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 503.0
HFD3_k127_4297920_20 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000229 140.0
HFD3_k127_4297920_21 HEAT repeats - - - 0.000000000000000000000000000007322 135.0
HFD3_k127_4297920_22 - - - - 0.00000000000000000000000000003453 121.0
HFD3_k127_4297920_23 PFAM helix-turn-helix- domain containing protein AraC type - - - 0.0000000000000000000000000002593 117.0
HFD3_k127_4297920_24 Glycosyltransferase Family 4 - - - 0.000000000000000000000000107 122.0
HFD3_k127_4297920_25 - - - - 0.000000000000000000000001463 112.0
HFD3_k127_4297920_26 triphosphatase activity - - - 0.00000000000000000000000354 109.0
HFD3_k127_4297920_27 Protein of unknown function (DUF3298) - - - 0.00000000000000000000003095 113.0
HFD3_k127_4297920_28 DoxX K15977 - - 0.000000000000000000003052 98.0
HFD3_k127_4297920_29 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000001381 81.0
HFD3_k127_4297920_3 Peptidase dimerisation domain K01436 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009195 484.0
HFD3_k127_4297920_30 Family of unknown function (DUF5339) - - - 0.000000000004315 72.0
HFD3_k127_4297920_31 Nacht domain - - - 0.000000006673 68.0
HFD3_k127_4297920_32 Polymer-forming cytoskeletal - - - 0.0000002918 57.0
HFD3_k127_4297920_33 hmm pf03415 K08587 - 3.4.22.8 0.00003987 55.0
HFD3_k127_4297920_35 Putative zinc-finger - - - 0.0003753 52.0
HFD3_k127_4297920_4 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 411.0
HFD3_k127_4297920_5 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 299.0
HFD3_k127_4297920_6 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000168 284.0
HFD3_k127_4297920_7 MFS_1 like family K08151,K08153 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002067 287.0
HFD3_k127_4297920_8 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001422 259.0
HFD3_k127_4297920_9 Amidohydrolase K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000009388 263.0
HFD3_k127_4308962_0 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 608.0
HFD3_k127_4308962_1 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005713 341.0
HFD3_k127_4308962_2 PFAM Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 331.0
HFD3_k127_4308962_3 Highly conserved protein containing a thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003949 310.0
HFD3_k127_4308962_4 Hexapeptide repeat of succinyl-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001944 246.0
HFD3_k127_4311356_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 1.071e-197 645.0
HFD3_k127_4311356_10 UDP binding domain K00012 - 1.1.1.22 0.000000000000000000000000000000000000000004357 156.0
HFD3_k127_4311356_11 Radical SAM K22227 - - 0.00000000000000000000000000000000000001611 158.0
HFD3_k127_4311356_12 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000128 149.0
HFD3_k127_4311356_13 2OG-Fe(II) oxygenase superfamily K07336,K07394 - - 0.0000000000000000000000000000000009379 137.0
HFD3_k127_4311356_14 Lipid A 3-O-deacylase (PagL) - - - 0.00000000000000000000000000009824 124.0
HFD3_k127_4311356_15 Membrane - - - 0.0002185 50.0
HFD3_k127_4311356_2 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 531.0
HFD3_k127_4311356_3 Carbamoyltransferase C-terminus K00612 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004942 458.0
HFD3_k127_4311356_4 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 403.0
HFD3_k127_4311356_5 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008749 375.0
HFD3_k127_4311356_6 histidine kinase HAMP region domain protein K13598 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000065 359.0
HFD3_k127_4311356_7 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009025 328.0
HFD3_k127_4311356_8 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000001171 226.0
HFD3_k127_4311356_9 Enoyl-(Acyl carrier protein) reductase K00034,K03366 - 1.1.1.304,1.1.1.47,1.1.1.76 0.000000000000000000000000000000000000000000000000000002995 199.0
HFD3_k127_4329127_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000002266 235.0
HFD3_k127_4329127_1 peptidase M15B and M15C DD-carboxypeptidase VanY - - - 0.0000000000000000000006729 107.0
HFD3_k127_4329127_2 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000003355 74.0
HFD3_k127_4352280_0 Zinc-binding dehydrogenase - - - 1.5e-286 897.0
HFD3_k127_4352280_1 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005069 525.0
HFD3_k127_4352280_10 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.000000000000000000000000000000000000000000002655 181.0
HFD3_k127_4352280_11 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000009073 169.0
HFD3_k127_4352280_12 methyltransferase - - - 0.00000000000000000000000000008428 124.0
HFD3_k127_4352280_13 Cellulose Binding Domain Type IV - - - 0.000000000000009602 89.0
HFD3_k127_4352280_14 PFAM Endonuclease Exonuclease phosphatase - - - 0.00000001236 67.0
HFD3_k127_4352280_15 Endonuclease/Exonuclease/phosphatase family - - - 0.0000002035 64.0
HFD3_k127_4352280_16 O-antigen ligase like membrane protein - - - 0.0000002454 63.0
HFD3_k127_4352280_2 transferase activity, transferring glycosyl groups K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006881 391.0
HFD3_k127_4352280_3 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 383.0
HFD3_k127_4352280_4 transferase activity, transferring glycosyl groups K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 331.0
HFD3_k127_4352280_5 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007988 330.0
HFD3_k127_4352280_6 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 308.0
HFD3_k127_4352280_7 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002099 276.0
HFD3_k127_4352280_8 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001207 264.0
HFD3_k127_4352280_9 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000005653 209.0
HFD3_k127_4380650_0 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 519.0
HFD3_k127_4380650_1 ABC-2 family transporter protein K19341 - - 0.000000000000000000000000000000000000000000000000007681 191.0
HFD3_k127_4380650_10 NosL K19342 - - 0.00000000000000000000003876 104.0
HFD3_k127_4380650_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000007958 57.0
HFD3_k127_4380650_12 - - - - 0.000006704 49.0
HFD3_k127_4380650_2 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000526 181.0
HFD3_k127_4380650_3 COG1131 ABC-type multidrug transport system, ATPase component K01990,K19340 - - 0.0000000000000000000000000000000000000000000002681 175.0
HFD3_k127_4380650_4 esterase - - - 0.00000000000000000000000000000000000000000001075 169.0
HFD3_k127_4380650_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K04750 - - 0.000000000000000000000000000000000000000002585 173.0
HFD3_k127_4380650_6 - - - - 0.00000000000000000000000000000002842 146.0
HFD3_k127_4380650_7 PFAM Formylglycine-generating sulfatase enzyme K18912 - 1.14.99.50 0.0000000000000000000000000548 121.0
HFD3_k127_4380650_8 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000002291 121.0
HFD3_k127_4380650_9 Glyoxalase-like domain - - - 0.00000000000000000000000552 117.0
HFD3_k127_4405731_0 Hydrolase CocE NonD family - - - 1.885e-313 969.0
HFD3_k127_4405731_1 PFAM ABC transporter related K06020 - 3.6.3.25 1.358e-307 948.0
HFD3_k127_4405731_10 PDZ domain (Also known as DHR or GLGF) K08372 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 411.0
HFD3_k127_4405731_11 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 419.0
HFD3_k127_4405731_12 protein with SCP PR1 domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006929 358.0
HFD3_k127_4405731_13 IgA Peptidase M64 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 345.0
HFD3_k127_4405731_14 Domain of unknown function (DUF5122) beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 353.0
HFD3_k127_4405731_15 DUF218 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005239 312.0
HFD3_k127_4405731_16 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 308.0
HFD3_k127_4405731_17 CHAT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002409 265.0
HFD3_k127_4405731_18 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000001407 257.0
HFD3_k127_4405731_19 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000001723 249.0
HFD3_k127_4405731_2 N-acetyldiaminopimelate deacetylase activity K12941 - - 2.35e-244 763.0
HFD3_k127_4405731_20 CHAT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000007592 235.0
HFD3_k127_4405731_21 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000209 185.0
HFD3_k127_4405731_22 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000000003284 175.0
HFD3_k127_4405731_23 SEC-C domain protein K09858 - - 0.000000000000000000000000000000000000000000001425 169.0
HFD3_k127_4405731_24 Extracellular nuclease - - - 0.00000000000000000000000000000000000000000003664 187.0
HFD3_k127_4405731_25 transcriptional regulator - - - 0.000000000000000000000000000000000003216 149.0
HFD3_k127_4405731_26 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000007399 137.0
HFD3_k127_4405731_27 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000008027 114.0
HFD3_k127_4405731_28 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000000000000000001291 119.0
HFD3_k127_4405731_29 - - - - 0.0000000000000000005756 94.0
HFD3_k127_4405731_3 CarboxypepD_reg-like domain - - - 1.186e-235 774.0
HFD3_k127_4405731_30 - - - - 0.00000000000000001447 91.0
HFD3_k127_4405731_31 Putative phosphatase (DUF442) - - - 0.0000000000000002352 94.0
HFD3_k127_4405731_32 - - - - 0.0000000000000005709 85.0
HFD3_k127_4405731_33 - - - - 0.000000000000002711 80.0
HFD3_k127_4405731_34 Protein of unknown function (DUF3761) - - - 0.0000000003584 64.0
HFD3_k127_4405731_35 Bacterial Ig-like domain (group 3) - - - 0.0000026 62.0
HFD3_k127_4405731_36 - - - - 0.000003068 51.0
HFD3_k127_4405731_4 WD domain, G-beta repeat - - - 1.477e-226 747.0
HFD3_k127_4405731_5 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 615.0
HFD3_k127_4405731_6 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 584.0
HFD3_k127_4405731_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 515.0
HFD3_k127_4405731_8 beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 441.0
HFD3_k127_4405731_9 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004406 426.0
HFD3_k127_4414358_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1166.0
HFD3_k127_4414358_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 457.0
HFD3_k127_4414358_10 - - - - 0.000006265 54.0
HFD3_k127_4414358_11 YtkA-like - - - 0.00002136 52.0
HFD3_k127_4414358_2 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000743 355.0
HFD3_k127_4414358_3 SelR domain K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000001058 204.0
HFD3_k127_4414358_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K15727 - - 0.00000000000000000000000000000000000000000000001031 188.0
HFD3_k127_4414358_5 Cytochrome C biogenesis protein transmembrane region - - - 0.000000000000000000000000000000000000000000004032 176.0
HFD3_k127_4414358_6 Smr domain - - - 0.0000000000000000000000000000002788 124.0
HFD3_k127_4414358_7 COG1538 Outer membrane protein K15725 - - 0.000000000000000000000001882 117.0
HFD3_k127_4414358_8 TIGRFAM TonB K03832 - - 0.0000000008562 66.0
HFD3_k127_4414358_9 serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.0000001587 63.0
HFD3_k127_4418674_0 glycoside hydrolase family 38 K01191 - 3.2.1.24 0.0 1424.0
HFD3_k127_4418674_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.089e-281 889.0
HFD3_k127_4418674_10 cluster binding protein K18929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 469.0
HFD3_k127_4418674_11 Amidohydrolase family K05603 - 3.5.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 455.0
HFD3_k127_4418674_12 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 409.0
HFD3_k127_4418674_13 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005435 395.0
HFD3_k127_4418674_14 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 388.0
HFD3_k127_4418674_15 Peptidase dimerisation domain K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 390.0
HFD3_k127_4418674_16 D12 class N6 adenine-specific DNA methyltransferase K06223 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 357.0
HFD3_k127_4418674_17 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 358.0
HFD3_k127_4418674_18 PRMT5 arginine-N-methyltransferase K11434 - 2.1.1.319 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007481 338.0
HFD3_k127_4418674_19 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 341.0
HFD3_k127_4418674_2 Urocanase Rossmann-like domain K01712 - 4.2.1.49 1.951e-271 844.0
HFD3_k127_4418674_20 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01707 - 4.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 326.0
HFD3_k127_4418674_21 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 312.0
HFD3_k127_4418674_22 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007025 299.0
HFD3_k127_4418674_23 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 295.0
HFD3_k127_4418674_24 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004035 293.0
HFD3_k127_4418674_25 metal-dependent hydrolase of the TIM-barrel fold K07046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003506 282.0
HFD3_k127_4418674_26 HPr kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002847 278.0
HFD3_k127_4418674_27 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source K18928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000064 268.0
HFD3_k127_4418674_28 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000007792 260.0
HFD3_k127_4418674_29 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000129 255.0
HFD3_k127_4418674_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.051e-229 718.0
HFD3_k127_4418674_30 Predicted integral membrane protein (DUF2270) - - - 0.000000000000000000000000000000000000000000000000000000000000007038 234.0
HFD3_k127_4418674_31 2Fe-2S -binding K13483 - - 0.000000000000000000000000000000000000000000000000000000002008 206.0
HFD3_k127_4418674_32 MoaE protein K21142 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000003189 201.0
HFD3_k127_4418674_33 Uncharacterised nucleotidyltransferase - - - 0.000000000000000000000000000000000000000000000000000001987 205.0
HFD3_k127_4418674_34 Peptidase of plants and bacteria - - - 0.00000000000000000000000000000000000000000000000000001714 195.0
HFD3_k127_4418674_35 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000001204 164.0
HFD3_k127_4418674_36 ATP-dependent protease La (LON) substrate-binding domain K01338 - 3.4.21.53 0.000000000000000000000000000000000000001408 157.0
HFD3_k127_4418674_37 - - - - 0.000000000000000000000000000000000000001527 158.0
HFD3_k127_4418674_38 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000004138 122.0
HFD3_k127_4418674_39 LUD domain K00782 - - 0.0000000000000000000005898 104.0
HFD3_k127_4418674_4 ATPases associated with a variety of cellular activities K06147 - - 1.066e-204 655.0
HFD3_k127_4418674_40 - - - - 0.000000000000000000006757 105.0
HFD3_k127_4418674_41 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000000000000000007597 86.0
HFD3_k127_4418674_42 Protein of unknown function (DUF1326) - - - 0.00000000000000003005 91.0
HFD3_k127_4418674_43 Transcription factor zinc-finger K09981 - - 0.000000000003026 70.0
HFD3_k127_4418674_44 rhodanese-related sulfurtransferase - - - 0.000000002387 62.0
HFD3_k127_4418674_45 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07669,K07672 - - 0.00000000414 64.0
HFD3_k127_4418674_46 Resolvase, N terminal domain - - - 0.000008758 48.0
HFD3_k127_4418674_5 Aromatic amino acid lyase K01745 - 4.3.1.3 1.065e-200 637.0
HFD3_k127_4418674_6 ABC transporter K10441 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 597.0
HFD3_k127_4418674_7 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 484.0
HFD3_k127_4418674_8 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K11177 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003144 498.0
HFD3_k127_4418674_9 PFAM Alcohol dehydrogenase GroES-like domain K00008,K00060 - 1.1.1.103,1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009945 478.0
HFD3_k127_450894_0 Carboxypeptidase regulatory-like domain - - - 5.296e-213 701.0
HFD3_k127_450894_1 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005686 423.0
HFD3_k127_450894_10 Conserved Protein - - - 0.000000000000001192 80.0
HFD3_k127_450894_11 Response regulator, receiver K11443 - - 0.000000000001826 74.0
HFD3_k127_450894_12 Tetratricopeptide repeat - - - 0.0003875 52.0
HFD3_k127_450894_2 chaperone-mediated protein folding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 425.0
HFD3_k127_450894_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007965 368.0
HFD3_k127_450894_4 M1 (1,4-beta-N-acetylmuramidase) K07273 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005374 300.0
HFD3_k127_450894_5 Enoyl-CoA hydratase K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000159 279.0
HFD3_k127_450894_6 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001162 276.0
HFD3_k127_450894_7 TIR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000133 260.0
HFD3_k127_450894_8 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000003708 125.0
HFD3_k127_450894_9 histone H2A K63-linked ubiquitination K01205,K07004,K12132 - 2.7.11.1,3.2.1.50 0.0000000000000000000003569 108.0
HFD3_k127_4514447_0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 312.0
HFD3_k127_4514447_1 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002003 277.0
HFD3_k127_4514447_10 gluconolactonase K01053 - 3.1.1.17 0.0000003761 55.0
HFD3_k127_4514447_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000003273 161.0
HFD3_k127_4514447_3 methylamine metabolic process K15977 - - 0.0000000000000000000000000000000000000004979 158.0
HFD3_k127_4514447_4 TIR domain - - - 0.00000000000000000000000000000000000000122 160.0
HFD3_k127_4514447_5 oxidoreductase activity - - - 0.000000000000000000000000000000000003643 156.0
HFD3_k127_4514447_6 outer membrane efflux protein - - - 0.000000000000000000000000000000001402 145.0
HFD3_k127_4514447_7 - - - - 0.000000000000000000000000000136 117.0
HFD3_k127_4514447_8 Tyrosine phosphatase family - - - 0.000000000000000000005732 100.0
HFD3_k127_4514447_9 AntiSigma factor - - - 0.0000000000000000001106 99.0
HFD3_k127_452065_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 528.0
HFD3_k127_452065_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000006238 220.0
HFD3_k127_452065_2 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000002838 146.0
HFD3_k127_4521669_0 Carboxypeptidase regulatory-like domain - - - 2.937e-228 753.0
HFD3_k127_4521669_1 Vault protein inter-alpha-trypsin domain K07114 - - 3.017e-194 634.0
HFD3_k127_4521669_10 beta-fructofuranosidase activity - - - 0.00000000000000000000000000000000000000000000000000000000001606 220.0
HFD3_k127_4521669_11 Belongs to the DapB family K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000593 192.0
HFD3_k127_4521669_12 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000004502 169.0
HFD3_k127_4521669_13 Gram-negative bacterial TonB protein C-terminal - - - 0.000000000000000000000007048 115.0
HFD3_k127_4521669_14 - - - - 0.0000000000000000008972 99.0
HFD3_k127_4521669_15 gluconolactonase activity - - - 0.000000000004961 69.0
HFD3_k127_4521669_16 PFAM Pentapeptide repeats (8 copies) - - - 0.00000000001844 76.0
HFD3_k127_4521669_17 zinc metalloprotease K11749 - - 0.0000000008817 66.0
HFD3_k127_4521669_18 Anaphase-promoting complex, cyclosome, subunit 3 K03350 GO:0000003,GO:0000151,GO:0000152,GO:0000209,GO:0000278,GO:0000375,GO:0000377,GO:0000398,GO:0001775,GO:0003002,GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005680,GO:0005737,GO:0005813,GO:0005815,GO:0005819,GO:0005829,GO:0005856,GO:0006139,GO:0006396,GO:0006397,GO:0006464,GO:0006508,GO:0006511,GO:0006725,GO:0006807,GO:0006810,GO:0006887,GO:0007049,GO:0007088,GO:0007091,GO:0007275,GO:0007338,GO:0007343,GO:0007346,GO:0007389,GO:0008150,GO:0008152,GO:0008283,GO:0008356,GO:0008380,GO:0009056,GO:0009057,GO:0009566,GO:0009798,GO:0009948,GO:0009949,GO:0009952,GO:0009987,GO:0010467,GO:0010498,GO:0010564,GO:0010965,GO:0015630,GO:0016070,GO:0016071,GO:0016192,GO:0016567,GO:0016740,GO:0017156,GO:0019538,GO:0019787,GO:0019899,GO:0019902,GO:0019903,GO:0019941,GO:0019953,GO:0022402,GO:0022414,GO:0030163,GO:0031145,GO:0031461,GO:0031974,GO:0031981,GO:0032446,GO:0032501,GO:0032502,GO:0032940,GO:0032991,GO:0033043,GO:0033044,GO:0033045,GO:0033047,GO:0034641,GO:0036211,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043632,GO:0043900,GO:0043901,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044770,GO:0044772,GO:0044784,GO:0045055,GO:0046483,GO:0046903,GO:0048519,GO:0048856,GO:0050789,GO:0050794,GO:0051128,GO:0051179,GO:0051234,GO:0051301,GO:0051603,GO:0051704,GO:0051726,GO:0051783,GO:0051983,GO:0060467,GO:0060468,GO:0060471,GO:0061630,GO:0061659,GO:0065001,GO:0065007,GO:0070013,GO:0070647,GO:0070979,GO:0071704,GO:0080154,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1903047,GO:1905818,GO:1990234,GO:2000241,GO:2000242 - 0.000000004925 68.0
HFD3_k127_4521669_2 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007216 388.0
HFD3_k127_4521669_3 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 378.0
HFD3_k127_4521669_4 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009222 364.0
HFD3_k127_4521669_5 PFAM peptidase K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 324.0
HFD3_k127_4521669_6 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005396 321.0
HFD3_k127_4521669_7 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001063 287.0
HFD3_k127_4521669_8 PFAM Aminotransferase, class I K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000005954 257.0
HFD3_k127_4521669_9 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0000000000000000000000000000000000000000000000000000000000006271 229.0
HFD3_k127_4537521_0 Large family of predicted nucleotide-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 406.0
HFD3_k127_4537521_1 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 336.0
HFD3_k127_4537521_2 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001176 244.0
HFD3_k127_4537521_3 - - - - 0.00000000000000000000000000000000000000000000001122 174.0
HFD3_k127_4537521_4 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.000000000000000000000000000000000002508 144.0
HFD3_k127_4537521_5 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000006809 135.0
HFD3_k127_4537521_6 Protein of unknown function, DUF393 - - - 0.000000000000000000000000000006971 122.0
HFD3_k127_4537521_7 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000729 102.0
HFD3_k127_4537521_8 - - - - 0.00001941 55.0
HFD3_k127_4603916_0 ABC-type antimicrobial peptide transport system, permease component - - - 8.308e-203 659.0
HFD3_k127_4603916_1 Aldo keto reductase K05275 - 1.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 517.0
HFD3_k127_4603916_10 Predicted membrane protein (DUF2306) - - - 0.0000000000000000000000000000000000000000000000000000000000001482 220.0
HFD3_k127_4603916_12 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000976 184.0
HFD3_k127_4603916_13 - - - - 0.000000000000000000000000000000000000000000001727 171.0
HFD3_k127_4603916_14 CBD_II K01179,K01183 - 3.2.1.14,3.2.1.4 0.00000000000000000000000000000000007894 157.0
HFD3_k127_4603916_15 protein trimerization - - - 0.00000000000000000000000000000001083 132.0
HFD3_k127_4603916_16 PFAM BNR Asp-box repeat - - - 0.000000000000000000000005518 121.0
HFD3_k127_4603916_17 transmembrane transporter activity - - - 0.0000003744 57.0
HFD3_k127_4603916_19 Clostripain family - - - 0.0005125 49.0
HFD3_k127_4603916_2 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006358 538.0
HFD3_k127_4603916_3 alpha-L-arabinofuranosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004049 482.0
HFD3_k127_4603916_4 metallopeptidase activity K06212,K06402 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031224,GO:0031226,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004999 404.0
HFD3_k127_4603916_5 SAF K01685 - 4.2.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 396.0
HFD3_k127_4603916_6 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 362.0
HFD3_k127_4603916_7 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 383.0
HFD3_k127_4603916_8 glucosamine-6-phosphate deaminase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005449 344.0
HFD3_k127_4603916_9 phytanoyl-CoA dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000003856 240.0
HFD3_k127_4667331_0 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 1.766e-248 780.0
HFD3_k127_4667331_1 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006801 496.0
HFD3_k127_4667331_10 histone H2A K63-linked ubiquitination K08884,K11894 - 2.7.11.1 0.00000000000002533 87.0
HFD3_k127_4667331_11 - - - - 0.00000000000007322 76.0
HFD3_k127_4667331_2 PFAM Peptidase M16 inactive domain K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006241 475.0
HFD3_k127_4667331_3 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005159 473.0
HFD3_k127_4667331_4 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001623 286.0
HFD3_k127_4667331_5 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000001713 214.0
HFD3_k127_4667331_6 Histidine kinase K02668,K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000001249 218.0
HFD3_k127_4667331_7 Chaperone of endosialidase - - - 0.00000000000000000000000000000000000000000000000000000001845 209.0
HFD3_k127_4667331_8 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000002151 192.0
HFD3_k127_4667331_9 AcrB/AcrD/AcrF family K03296 - - 0.000000000000000000000000000000000000000000002099 179.0
HFD3_k127_4668186_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 511.0
HFD3_k127_4668186_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 358.0
HFD3_k127_4668186_2 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009337 278.0
HFD3_k127_4672723_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007994 576.0
HFD3_k127_4672723_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 335.0
HFD3_k127_4672723_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004552 277.0
HFD3_k127_4672723_3 beta-ketoacyl-acyl-carrier-protein synthase III activity K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000004864 234.0
HFD3_k127_4672723_4 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000000000000005297 209.0
HFD3_k127_4672723_5 PFAM von Willebrand factor type A - - - 0.000000000000000000000000000000000000000001017 172.0
HFD3_k127_4672723_6 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) K02491,K13533 - 2.7.13.3 0.000000000000000000000000000000000000000002677 181.0
HFD3_k127_4672723_7 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K10697 - - 0.00000000000000000003705 108.0
HFD3_k127_4672723_8 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.000000000000001118 76.0
HFD3_k127_4719107_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005705 341.0
HFD3_k127_4719107_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.5 0.0000000000000000000000000000000000004148 149.0
HFD3_k127_4719107_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000004776 72.0
HFD3_k127_4719107_3 Lysin motif - - - 0.0000000005158 71.0
HFD3_k127_472159_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1206.0
HFD3_k127_472159_1 PFAM Amino acid permease K03294 - - 1.115e-224 711.0
HFD3_k127_472159_10 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000005814 142.0
HFD3_k127_472159_11 Iron-sulphur cluster biosynthesis - - - 0.000000000000000000000000000000000001097 142.0
HFD3_k127_472159_12 PFAM Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000004329 144.0
HFD3_k127_472159_13 deaminated base DNA N-glycosylase activity K21929 - 3.2.2.27 0.00000000000000000000000000000000006515 143.0
HFD3_k127_472159_14 Urate oxidase N-terminal - - - 0.00000000000000000000000000000326 130.0
HFD3_k127_472159_15 Universal stress protein - - - 0.00000000000001852 83.0
HFD3_k127_472159_16 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.000000000001086 70.0
HFD3_k127_472159_17 Rhodanese Homology Domain - - - 0.00000000001861 68.0
HFD3_k127_472159_18 outer membrane autotransporter barrel domain protein - - - 0.000001754 57.0
HFD3_k127_472159_2 5TM C-terminal transporter carbon starvation CstA K06200 - - 7.777e-218 692.0
HFD3_k127_472159_3 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 364.0
HFD3_k127_472159_4 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006558 348.0
HFD3_k127_472159_5 cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001949 288.0
HFD3_k127_472159_6 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000008216 236.0
HFD3_k127_472159_7 Acetyltransferase (GNAT) domain - GO:0003674,GO:0003824,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747 - 0.000000000000000000000000000000000000000000001321 170.0
HFD3_k127_472159_8 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.00000000000000000000000000000000000000001082 166.0
HFD3_k127_472159_9 PFAM BioY protein K03523 - - 0.0000000000000000000000000000000000000002285 156.0
HFD3_k127_4737002_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 4.409e-247 773.0
HFD3_k127_4737002_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1.626e-203 643.0
HFD3_k127_4737002_10 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000004851 250.0
HFD3_k127_4737002_11 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000001204 252.0
HFD3_k127_4737002_12 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000004076 233.0
HFD3_k127_4737002_13 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000005336 205.0
HFD3_k127_4737002_14 PFAM Peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000000000001296 187.0
HFD3_k127_4737002_15 - - - - 0.000000000000000000000000000000000000000000005492 171.0
HFD3_k127_4737002_16 Involved in DNA repair and RecF pathway recombination K03474,K03584 GO:0008150,GO:0009314,GO:0009628,GO:0050896 2.6.99.2 0.000000000000000000000000000000000000006925 154.0
HFD3_k127_4737002_17 adenosylhomocysteinase activity K01251 - 3.3.1.1 0.0000000000000000000000000000000000009717 156.0
HFD3_k127_4737002_18 diguanylate cyclase - - - 0.00000000000000000000000000000519 137.0
HFD3_k127_4737002_19 Fibronectin type III domain - - - 0.000000000000000000000000001189 124.0
HFD3_k127_4737002_2 S-adenosyl-L-homocysteine hydrolase, NAD binding domain K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 8.026e-201 632.0
HFD3_k127_4737002_20 - - - - 0.0000000000000000000001418 102.0
HFD3_k127_4737002_21 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000003123 94.0
HFD3_k127_4737002_22 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000001206 89.0
HFD3_k127_4737002_23 Belongs to the UPF0374 family K07586 - - 0.0000000000000006125 83.0
HFD3_k127_4737002_24 Fibronectin type 3 domain - - - 0.000000000000006634 86.0
HFD3_k127_4737002_25 Tetratricopeptide repeat - - - 0.0000002324 62.0
HFD3_k127_4737002_26 Retroviral aspartyl protease - - - 0.0003034 52.0
HFD3_k127_4737002_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 543.0
HFD3_k127_4737002_4 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 543.0
HFD3_k127_4737002_5 Protein of unknown function (DUF1343) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 410.0
HFD3_k127_4737002_6 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 317.0
HFD3_k127_4737002_7 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K13810 GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 297.0
HFD3_k127_4737002_8 Domain of unknown function (DUF2437) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001786 267.0
HFD3_k127_4737002_9 Permease, YjgP YjgQ - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003325 286.0
HFD3_k127_4788497_0 cellulose binding - - - 0.0 1102.0
HFD3_k127_4788497_1 PFAM D-aminoacylase, C-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 538.0
HFD3_k127_4788497_2 esterase - - - 0.00000000000000000000000000000000000000000000000000937 183.0
HFD3_k127_4789980_0 Domain of unknown function (DUF5117) - - - 0.0 1015.0
HFD3_k127_4789980_1 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 3.382e-246 774.0
HFD3_k127_4789980_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000741 501.0
HFD3_k127_4789980_11 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 497.0
HFD3_k127_4789980_12 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 496.0
HFD3_k127_4789980_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 491.0
HFD3_k127_4789980_14 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 477.0
HFD3_k127_4789980_15 amino acid peptide transporter K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 449.0
HFD3_k127_4789980_16 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 429.0
HFD3_k127_4789980_17 phosphoglucomutase phosphomannomutase alpha beta alpha domain II K01840 - 5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 409.0
HFD3_k127_4789980_18 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006878 412.0
HFD3_k127_4789980_19 Dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 392.0
HFD3_k127_4789980_20 ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 384.0
HFD3_k127_4789980_21 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 374.0
HFD3_k127_4789980_22 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 365.0
HFD3_k127_4789980_23 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 361.0
HFD3_k127_4789980_24 thiamine diphosphate biosynthetic process K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 353.0
HFD3_k127_4789980_25 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 351.0
HFD3_k127_4789980_26 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 351.0
HFD3_k127_4789980_27 Domain of unknown function (DUF1731) K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 344.0
HFD3_k127_4789980_28 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003103 336.0
HFD3_k127_4789980_3 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 5.069e-196 622.0
HFD3_k127_4789980_30 PFAM transferase hexapeptide repeat containing protein K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 311.0
HFD3_k127_4789980_31 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000328 273.0
HFD3_k127_4789980_32 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000654 248.0
HFD3_k127_4789980_33 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000002405 215.0
HFD3_k127_4789980_34 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000003227 211.0
HFD3_k127_4789980_35 2 iron, 2 sulfur cluster binding K00334,K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000003951 192.0
HFD3_k127_4789980_36 Lamin Tail Domain K07004 - - 0.000000000000000000000000000000000000000000000000001476 208.0
HFD3_k127_4789980_37 heme binding K21472 - - 0.00000000000000000000000000000000000000000000003786 177.0
HFD3_k127_4789980_38 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000008497 168.0
HFD3_k127_4789980_39 lipoprotein localization to outer membrane K02004 - - 0.0000000000000000000000000000000000000000004327 180.0
HFD3_k127_4789980_4 Zinc carboxypeptidase K01278 - 3.4.14.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004359 594.0
HFD3_k127_4789980_40 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000001112 162.0
HFD3_k127_4789980_41 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000001585 160.0
HFD3_k127_4789980_42 Forkhead associated domain - - - 0.000000000000000000000000000000000000001519 166.0
HFD3_k127_4789980_43 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000000001686 151.0
HFD3_k127_4789980_44 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000001255 146.0
HFD3_k127_4789980_45 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000000000000000000000002244 152.0
HFD3_k127_4789980_46 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000006742 142.0
HFD3_k127_4789980_47 Peptidase family M1 domain - - - 0.00000000000000000000000000000001526 136.0
HFD3_k127_4789980_48 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000002693 126.0
HFD3_k127_4789980_49 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000001125 124.0
HFD3_k127_4789980_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004842 538.0
HFD3_k127_4789980_50 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000000002256 121.0
HFD3_k127_4789980_51 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000141 110.0
HFD3_k127_4789980_52 Ferredoxin - - - 0.0000000000000000000000004708 109.0
HFD3_k127_4789980_53 Involved in the tonB-independent uptake of proteins K03641 - - 0.00000000000000000000005177 116.0
HFD3_k127_4789980_54 Ribosomal L32p protein family K02911 - - 0.000000000000000000005291 94.0
HFD3_k127_4789980_55 Belongs to the peptidase S1C family - - - 0.000000000000000004016 98.0
HFD3_k127_4789980_56 - - - - 0.00000000000004578 83.0
HFD3_k127_4789980_57 thiamine biosynthesis protein ThiS K03154 - - 0.0000000000007383 74.0
HFD3_k127_4789980_58 peptidyl-tyrosine sulfation - - - 0.000000003395 68.0
HFD3_k127_4789980_59 GMP synthase (glutamine-hydrolyzing) activity K01951 - 6.3.5.2 0.00000005316 64.0
HFD3_k127_4789980_6 proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 520.0
HFD3_k127_4789980_60 Tetratricopeptide repeat-like domain - - - 0.00003793 54.0
HFD3_k127_4789980_61 membrane - - - 0.00004587 57.0
HFD3_k127_4789980_62 Putative zinc-finger - - - 0.0006895 50.0
HFD3_k127_4789980_7 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 529.0
HFD3_k127_4789980_8 RQC K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009707 527.0
HFD3_k127_4789980_9 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00282 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006145 501.0
HFD3_k127_4791519_0 Vault protein inter-alpha-trypsin domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005255 507.0
HFD3_k127_4791519_1 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 476.0
HFD3_k127_4791519_10 von Willebrand factor, type A - - - 0.000000000000000006025 96.0
HFD3_k127_4791519_11 PFAM regulatory protein GntR HTH K07979 - - 0.00000000000000001685 87.0
HFD3_k127_4791519_12 Major facilitator superfamily - - - 0.00000000000000001715 84.0
HFD3_k127_4791519_13 Tetratricopeptide repeats - - - 0.0000000000008216 73.0
HFD3_k127_4791519_15 oxidoreductase activity K12511 - - 0.0000000007008 72.0
HFD3_k127_4791519_16 sequence-specific DNA binding - - - 0.00009933 52.0
HFD3_k127_4791519_2 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 336.0
HFD3_k127_4791519_3 Peptidase M16 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006775 338.0
HFD3_k127_4791519_4 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 336.0
HFD3_k127_4791519_5 Peptidase M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001151 299.0
HFD3_k127_4791519_6 protein methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000005253 193.0
HFD3_k127_4791519_7 Photosynthesis system II assembly factor YCF48 - - - 0.00000000000000000000000000000000000000000000000008727 194.0
HFD3_k127_4791519_8 Zn peptidase K21686 - - 0.0000000000000000000000006964 111.0
HFD3_k127_4791519_9 iron ion homeostasis - - - 0.00000000000000000000038 109.0
HFD3_k127_4822147_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 5.721e-285 892.0
HFD3_k127_4822147_1 imidazolonepropionase activity K00466 - 1.13.12.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 540.0
HFD3_k127_4822147_10 Regulatory protein, FmdB - - - 0.00000000000000000005683 93.0
HFD3_k127_4822147_11 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00000001655 66.0
HFD3_k127_4822147_12 Domain of unknown function (DUF4388) K12132 - 2.7.11.1 0.00004975 54.0
HFD3_k127_4822147_2 PFAM aminotransferase, class I K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 540.0
HFD3_k127_4822147_3 tRNA (guanine(37)-N(1))-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000756 406.0
HFD3_k127_4822147_4 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002737 278.0
HFD3_k127_4822147_5 DEAD DEAH box helicase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004953 263.0
HFD3_k127_4822147_6 DSHCT - - - 0.0000000000000000000000000000000000000000000000000000000000000000009835 250.0
HFD3_k127_4822147_7 Transglycosylase SLT domain K08309 - - 0.000000000000000000000000000000000000000000000000000000000001127 236.0
HFD3_k127_4822147_8 nuclear chromosome segregation - - - 0.0000000000000000000000001382 121.0
HFD3_k127_4822147_9 PFAM response regulator receiver K07657 - - 0.0000000000000000000003083 100.0
HFD3_k127_4869641_0 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 582.0
HFD3_k127_4869641_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 474.0
HFD3_k127_4869641_10 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000003168 96.0
HFD3_k127_4869641_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008693 418.0
HFD3_k127_4869641_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008225 250.0
HFD3_k127_4869641_4 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000005676 183.0
HFD3_k127_4869641_5 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000002403 173.0
HFD3_k127_4869641_6 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000001539 167.0
HFD3_k127_4869641_7 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000001129 148.0
HFD3_k127_4869641_8 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000003237 132.0
HFD3_k127_4869641_9 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000001891 116.0
HFD3_k127_4871098_0 COG3209 Rhs family protein - - - 0.000000000000000000000000000000000000000002517 182.0
HFD3_k127_4871098_1 Phage integrase, N-terminal SAM-like domain K14059 - - 0.00000000000000000000000000002112 127.0
HFD3_k127_4871098_2 Sigma-54 interaction domain K19641 - - 0.0000000000000000000000000000904 119.0
HFD3_k127_4871098_3 Psort location Cytoplasmic, score - - - 0.000002014 51.0
HFD3_k127_4872567_0 Amino acid permease K03294 - - 2.351e-207 657.0
HFD3_k127_4872567_1 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005791 595.0
HFD3_k127_4872567_10 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000001952 139.0
HFD3_k127_4872567_11 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.000000000000000002769 98.0
HFD3_k127_4872567_12 Protein of unknown function (DUF664) - - - 0.0000000005164 68.0
HFD3_k127_4872567_13 galactose-1-phosphate K00965 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0008150,GO:0008152,GO:0008270,GO:0010646,GO:0010647,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032101,GO:0032103,GO:0032104,GO:0032106,GO:0032107,GO:0032109,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0044238,GO:0046872,GO:0046914,GO:0047345,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0065007,GO:0070566,GO:0071704,GO:0080040,GO:0080134,GO:0080135,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.7.7.12 0.00000003507 56.0
HFD3_k127_4872567_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 532.0
HFD3_k127_4872567_3 DNA polymerase K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 471.0
HFD3_k127_4872567_4 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791,K13019 - 5.1.3.14,5.1.3.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009317 432.0
HFD3_k127_4872567_5 Major facilitator Superfamily K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009255 376.0
HFD3_k127_4872567_6 Heparinase II/III-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009331 337.0
HFD3_k127_4872567_7 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005895 290.0
HFD3_k127_4872567_8 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000001699 210.0
HFD3_k127_4872567_9 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000005106 191.0
HFD3_k127_4887360_0 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 471.0
HFD3_k127_4887360_1 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000002843 210.0
HFD3_k127_4887360_2 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000003735 192.0
HFD3_k127_4887360_3 Protein of unknown function (DUF1572) - - - 0.000000000000000000000000000000000000000000000000001636 188.0
HFD3_k127_4887360_4 - - - - 0.000000000000000005439 92.0
HFD3_k127_4887360_5 multi-organism process - - - 0.000000000001439 81.0
HFD3_k127_4887409_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.222e-239 760.0
HFD3_k127_4887409_1 Amidase K01426 - 3.5.1.4 7.241e-203 644.0
HFD3_k127_4887409_10 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000000000000000000001457 111.0
HFD3_k127_4887409_11 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000001453 95.0
HFD3_k127_4887409_12 Tetratricopeptide repeat - - - 0.000000000000000008515 93.0
HFD3_k127_4887409_13 TIGRFAM TonB K03832 - - 0.00000000000000003298 91.0
HFD3_k127_4887409_14 Preprotein translocase, YajC subunit K03210 - - 0.00000000000000041 83.0
HFD3_k127_4887409_15 Belongs to the UPF0102 family K07460 - - 0.000000000000003831 81.0
HFD3_k127_4887409_16 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0022607,GO:0030288,GO:0030313,GO:0031647,GO:0031975,GO:0033218,GO:0036211,GO:0042277,GO:0042597,GO:0043163,GO:0043165,GO:0043170,GO:0043412,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0044764,GO:0045229,GO:0050821,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0060274,GO:0061024,GO:0061077,GO:0065007,GO:0065008,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564 5.2.1.8 0.000000000004009 78.0
HFD3_k127_4887409_17 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.00000000001384 72.0
HFD3_k127_4887409_18 Biopolymer transport protein K03559,K03560 - - 0.0000000009068 67.0
HFD3_k127_4887409_2 ABC transporter K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 469.0
HFD3_k127_4887409_3 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007657 440.0
HFD3_k127_4887409_4 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 432.0
HFD3_k127_4887409_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006364 408.0
HFD3_k127_4887409_6 MotA TolQ ExbB proton channel K03561,K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002476 276.0
HFD3_k127_4887409_7 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001999 250.0
HFD3_k127_4887409_8 Domain of unknown function (DUF4287) - - - 0.00000000000000000000000000000000000000000000000004799 183.0
HFD3_k127_4887409_9 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000000004123 172.0
HFD3_k127_4907215_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 627.0
HFD3_k127_4907215_1 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007098 483.0
HFD3_k127_4907215_10 Domain of unknown function (DUF4386) - - - 0.00000000394 67.0
HFD3_k127_4907215_11 TPR repeat - - - 0.00000002171 66.0
HFD3_k127_4907215_12 Tetratricopeptide repeat - - - 0.0000001695 63.0
HFD3_k127_4907215_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007407 494.0
HFD3_k127_4907215_3 hydroperoxide reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005582 434.0
HFD3_k127_4907215_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004085 274.0
HFD3_k127_4907215_5 - K00003,K00058,K01754,K04517,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,1.3.1.12,4.3.1.19 0.0000000000000000000000000000000000000000000000000005016 186.0
HFD3_k127_4907215_6 - - - - 0.000000000000000000002242 100.0
HFD3_k127_4907215_7 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.000000000000000000003853 94.0
HFD3_k127_4907215_8 PFAM Helix-turn-helix K07729 - - 0.0000000000000001375 81.0
HFD3_k127_4925230_0 beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 429.0
HFD3_k127_4925230_1 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007189 423.0
HFD3_k127_4925230_2 MOSC N-terminal beta barrel domain K07140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004462 261.0
HFD3_k127_4925230_3 DinB family - - - 0.0000000000000000000000001595 112.0
HFD3_k127_4925230_4 protein conserved in bacteria - - - 0.000000000000000004231 92.0
HFD3_k127_4925230_5 xylan catabolic process K03932 - - 0.00001489 55.0
HFD3_k127_4925230_6 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.00009233 54.0
HFD3_k127_4925590_0 Sortilin, neurotensin receptor 3, - - - 0.0 1423.0
HFD3_k127_4925590_1 transport - - - 0.0 1358.0
HFD3_k127_4925590_10 Peptidase family S58 K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 498.0
HFD3_k127_4925590_11 Uncharacterized ACR, YdiU/UPF0061 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 497.0
HFD3_k127_4925590_12 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009848 459.0
HFD3_k127_4925590_13 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005308 446.0
HFD3_k127_4925590_14 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 408.0
HFD3_k127_4925590_15 Dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 398.0
HFD3_k127_4925590_16 Belongs to the CinA family K03742 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 396.0
HFD3_k127_4925590_17 ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 396.0
HFD3_k127_4925590_18 symporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 380.0
HFD3_k127_4925590_19 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005819 333.0
HFD3_k127_4925590_2 transport - - - 5e-323 1029.0
HFD3_k127_4925590_20 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 294.0
HFD3_k127_4925590_21 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 300.0
HFD3_k127_4925590_22 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 289.0
HFD3_k127_4925590_23 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003488 284.0
HFD3_k127_4925590_24 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000002292 235.0
HFD3_k127_4925590_25 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000003011 191.0
HFD3_k127_4925590_26 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000955 188.0
HFD3_k127_4925590_27 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000004704 162.0
HFD3_k127_4925590_28 BadF BadG BcrA BcrD - GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006040,GO:0006044,GO:0006082,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0045127,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901071,GO:1901135,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000007294 168.0
HFD3_k127_4925590_29 LysR substrate binding domain K21703 - - 0.00000000000000000000000000000000000000741 157.0
HFD3_k127_4925590_3 beta-lactamase - - - 3.464e-255 810.0
HFD3_k127_4925590_30 Amino-transferase class IV K03342 - 2.6.1.85,4.1.3.38 0.00000000000000000000000000284 114.0
HFD3_k127_4925590_31 Universal stress protein family - - - 0.000000000000006917 81.0
HFD3_k127_4925590_32 TIGRFAM para-aminobenzoate synthase, subunit I K01665,K03342 - 2.6.1.85,4.1.3.38 0.000000002554 60.0
HFD3_k127_4925590_33 Bacterial regulatory proteins, gntR family - - - 0.000001727 54.0
HFD3_k127_4925590_34 SMART Rhodanese domain protein - - - 0.000003583 49.0
HFD3_k127_4925590_35 energy transducer activity K03832 - - 0.00001374 57.0
HFD3_k127_4925590_4 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 2.162e-247 779.0
HFD3_k127_4925590_5 Sodium:solute symporter family - - - 2.094e-244 769.0
HFD3_k127_4925590_6 Alpha/beta hydrolase family - - - 6.293e-208 666.0
HFD3_k127_4925590_7 Male sterility protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 607.0
HFD3_k127_4925590_8 PFAM D-aminoacylase, C-terminal region K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 558.0
HFD3_k127_4925590_9 Domain of unknown function (DUF3536) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008226 516.0
HFD3_k127_4929080_0 Serves to protect cells from the toxic effects of hydrogen peroxide K03781 - 1.11.1.6 2.003e-316 985.0
HFD3_k127_4929080_1 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009191 431.0
HFD3_k127_4929080_10 Cation transport regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000008828 231.0
HFD3_k127_4929080_11 GrpB protein - - - 0.000000000000000000000000000000000000000000000000000000000000000004648 230.0
HFD3_k127_4929080_12 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms K14205 - 2.3.2.3 0.00000000000000000000000000000000000000000000000000000000007339 218.0
HFD3_k127_4929080_13 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000434 195.0
HFD3_k127_4929080_14 Protein of unknown function (DUF1003) - - - 0.00000000000000000000000000000000000000000000002959 175.0
HFD3_k127_4929080_15 Protein of unknown function (DUF3037) - - - 0.0000000000000000000000000000000000000000000004132 170.0
HFD3_k127_4929080_16 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000002323 166.0
HFD3_k127_4929080_17 Bacterial regulatory proteins, tetR family - - - 0.0000000000006277 76.0
HFD3_k127_4929080_18 Uncharacterised conserved protein (DUF2156) - - - 0.0000000001076 72.0
HFD3_k127_4929080_19 membrane-associated protein - - - 0.0000005659 60.0
HFD3_k127_4929080_2 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 425.0
HFD3_k127_4929080_21 Bacterial virulence protein (VirJ) - - - 0.000703 51.0
HFD3_k127_4929080_3 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 395.0
HFD3_k127_4929080_4 Serine threonine protein kinase involved in cell cycle control - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005139 379.0
HFD3_k127_4929080_5 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007372 374.0
HFD3_k127_4929080_6 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 341.0
HFD3_k127_4929080_7 Ami_2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 308.0
HFD3_k127_4929080_8 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000001338 244.0
HFD3_k127_4929080_9 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002895 235.0
HFD3_k127_4943588_0 Glycosyl hydrolase family 1 K00067 - 1.1.1.133 5.955e-298 930.0
HFD3_k127_4943588_1 Belongs to the glycosyl hydrolase 13 family K21575 - 3.2.1.135 6.132e-290 906.0
HFD3_k127_4943588_10 ankyrin repeat K06867 - - 0.000000000001181 79.0
HFD3_k127_4943588_11 COG1596 Periplasmic protein involved in polysaccharide export K20988 - - 0.00005539 55.0
HFD3_k127_4943588_12 PFAM Tetratricopeptide repeat - - - 0.0003901 53.0
HFD3_k127_4943588_13 COG1596 Periplasmic protein involved in polysaccharide export K01991 - - 0.0009002 51.0
HFD3_k127_4943588_2 Belongs to the glycosyl hydrolase 2 family - - - 3.647e-254 796.0
HFD3_k127_4943588_3 PFAM UDP-galactopyranose mutase, C-terminal K01854 - 5.4.99.9 3.743e-206 648.0
HFD3_k127_4943588_4 Aminotransferase class-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 591.0
HFD3_k127_4943588_5 PFAM UDP-galactopyranose mutase K01854 - 5.4.99.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 511.0
HFD3_k127_4943588_6 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 413.0
HFD3_k127_4943588_7 Uncharacterized conserved protein (COG2071) K09166 - - 0.0000000000000000000000000000000000000000000000000000000002552 211.0
HFD3_k127_4943588_8 cell shape determining protein MreB K03569 - - 0.000000000000009732 74.0
HFD3_k127_4943588_9 Flavin containing amine oxidoreductase - - - 0.00000000000006455 73.0
HFD3_k127_4952803_0 Cytochrome c - - - 0.0 1035.0
HFD3_k127_4952803_1 Protein of unknown function, DUF255 K06888 - - 7.712e-237 751.0
HFD3_k127_4952803_10 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 388.0
HFD3_k127_4952803_11 ABC transporter K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 319.0
HFD3_k127_4952803_12 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 300.0
HFD3_k127_4952803_13 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000007357 263.0
HFD3_k127_4952803_14 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000003104 224.0
HFD3_k127_4952803_15 deoxyhypusine monooxygenase activity K00627,K02160,K07402 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000006647 211.0
HFD3_k127_4952803_16 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000002518 209.0
HFD3_k127_4952803_17 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000000000000000000379 204.0
HFD3_k127_4952803_18 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000003642 198.0
HFD3_k127_4952803_19 4Fe-4S binding domain K00395,K02572,K03616 - 1.8.99.2 0.00000000000000000000000000000000000000000000000002286 181.0
HFD3_k127_4952803_2 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K00311 - 1.5.5.1 1.364e-202 644.0
HFD3_k127_4952803_20 heme a metabolic process K02259,K03110 - - 0.00000000000000000000000000000000000000002001 165.0
HFD3_k127_4952803_21 SCO1/SenC K07152,K08976 - - 0.0000000000000000000000000000000000000013 151.0
HFD3_k127_4952803_22 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000000000000000000005223 145.0
HFD3_k127_4952803_23 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000001179 130.0
HFD3_k127_4952803_24 PFAM cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000003711 119.0
HFD3_k127_4952803_27 Cation transport regulator - - - 0.0000000002526 70.0
HFD3_k127_4952803_28 DNA-directed 5'-3' RNA polymerase activity K03060 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.000002895 52.0
HFD3_k127_4952803_3 Belongs to the heme-copper respiratory oxidase family K02274 - 1.9.3.1 3.117e-197 632.0
HFD3_k127_4952803_4 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 580.0
HFD3_k127_4952803_5 metallocarboxypeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009006 571.0
HFD3_k127_4952803_6 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 438.0
HFD3_k127_4952803_7 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008143 433.0
HFD3_k127_4952803_8 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 421.0
HFD3_k127_4952803_9 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 430.0
HFD3_k127_4953887_0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 556.0
HFD3_k127_4953887_1 - K00262 - 1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 462.0
HFD3_k127_4953887_2 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005096 357.0
HFD3_k127_4953887_3 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 319.0
HFD3_k127_4953887_4 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000000000000000000000000000000000005543 239.0
HFD3_k127_5024266_0 MFS/sugar transport protein K16211 - - 2.851e-210 664.0
HFD3_k127_5024266_1 Cyclomaltodextrinase, N-terminal K21575 - 3.2.1.135 6.03e-203 649.0
HFD3_k127_5024266_2 Glucodextranase, domain N K01178 - 3.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000879 578.0
HFD3_k127_5024266_3 Maltogenic Amylase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 314.0
HFD3_k127_5024266_4 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 299.0
HFD3_k127_5025783_0 regulation of DNA-templated transcription, elongation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 514.0
HFD3_k127_5025783_1 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 371.0
HFD3_k127_5025783_2 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 325.0
HFD3_k127_5025783_3 Protein involved in meta-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002107 273.0
HFD3_k127_5025783_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000018 260.0
HFD3_k127_5025783_5 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000002643 172.0
HFD3_k127_5025783_6 Domain of unknown function (DUF4136) - - - 0.00000000000116 76.0
HFD3_k127_5053318_0 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006452 404.0
HFD3_k127_5053318_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 385.0
HFD3_k127_5053318_2 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 361.0
HFD3_k127_5053318_3 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000171 304.0
HFD3_k127_5053318_4 PFAM MbtH domain protein K05375,K09190 - - 0.0000000000000000000000000000000000000000000000000000000000000000001645 235.0
HFD3_k127_5053318_5 - - - - 0.000000000000000000000000008795 112.0
HFD3_k127_5053318_6 Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components K05785 - - 0.000000000000003125 82.0
HFD3_k127_5053318_8 Condensation domain - - - 0.0000002116 58.0
HFD3_k127_5137037_0 cellulose binding - - - 2.27e-205 660.0
HFD3_k127_5137037_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 577.0
HFD3_k127_5137037_10 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 305.0
HFD3_k127_5137037_11 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005598 302.0
HFD3_k127_5137037_12 Domain of unknown function (DUF4162) K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 299.0
HFD3_k127_5137037_13 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006421 302.0
HFD3_k127_5137037_14 PFAM Glutamine cyclotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003994 280.0
HFD3_k127_5137037_15 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001403 277.0
HFD3_k127_5137037_16 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003123 271.0
HFD3_k127_5137037_17 Uracil DNA glycosylase superfamily K03649 - 3.2.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000007068 258.0
HFD3_k127_5137037_18 Domain of unknown function (DUF3488) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000165 280.0
HFD3_k127_5137037_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 524.0
HFD3_k127_5137037_20 carboxylic acid catabolic process - - - 0.00000000000000000000000000000000000000003065 161.0
HFD3_k127_5137037_21 oxidoreductase activity - - - 0.00000000000000000000000000000000001702 156.0
HFD3_k127_5137037_22 heat shock protein DnaJ K05516 - - 0.000000000000000000000000000000001052 137.0
HFD3_k127_5137037_23 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000209 130.0
HFD3_k127_5137037_24 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000001561 106.0
HFD3_k127_5137037_25 cheY-homologous receiver domain - - - 0.00000000000000000000005398 102.0
HFD3_k127_5137037_26 PFAM Adenylate cyclase K05873 - 4.6.1.1 0.00000000000000000000009373 106.0
HFD3_k127_5137037_27 transmembrane transporter activity - - - 0.00000000004353 69.0
HFD3_k127_5137037_28 - - - - 0.00008059 54.0
HFD3_k127_5137037_3 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 467.0
HFD3_k127_5137037_4 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008658 425.0
HFD3_k127_5137037_5 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004565 404.0
HFD3_k127_5137037_6 Belongs to the proline racemase family K01777 - 5.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006974 399.0
HFD3_k127_5137037_7 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005861 397.0
HFD3_k127_5137037_8 Protein of unknown function (DUF1624) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007966 380.0
HFD3_k127_5137037_9 Hydrolase Family 16 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 323.0
HFD3_k127_51571_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 1.08e-264 826.0
HFD3_k127_51571_1 tRNA synthetases class I (E and Q), catalytic domain K01885 - 6.1.1.17 3.131e-204 648.0
HFD3_k127_51571_2 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.0000000000000000000000000003546 116.0
HFD3_k127_51571_3 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 0.000000000000000000000000003097 116.0
HFD3_k127_51571_4 Peptidase family S58 - - - 0.00000000000000000000000001377 115.0
HFD3_k127_51571_5 Protein of unknown function (DUF3995) - - - 0.00000009651 59.0
HFD3_k127_51571_6 PFAM transposase mutator type - - - 0.000002231 52.0
HFD3_k127_5158196_0 Ribosomal protein S1 K02945 - - 1.624e-206 659.0
HFD3_k127_5158196_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 592.0
HFD3_k127_5158196_10 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 305.0
HFD3_k127_5158196_11 ArgK protein K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006725 304.0
HFD3_k127_5158196_12 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002282 283.0
HFD3_k127_5158196_13 pyrroloquinoline quinone binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008434 280.0
HFD3_k127_5158196_14 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001185 253.0
HFD3_k127_5158196_15 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000006666 240.0
HFD3_k127_5158196_16 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000009509 216.0
HFD3_k127_5158196_17 metalloendopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000008591 210.0
HFD3_k127_5158196_18 PFAM histidine triad (HIT) protein K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000000862 197.0
HFD3_k127_5158196_19 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000001606 187.0
HFD3_k127_5158196_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 512.0
HFD3_k127_5158196_20 Peptidase family M50 K06402 - - 0.000000000000000000000000000000000000000001818 164.0
HFD3_k127_5158196_21 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000007564 164.0
HFD3_k127_5158196_22 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.0000000000000000000000000000000000000002095 156.0
HFD3_k127_5158196_23 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.00000000000000000000000000000001971 129.0
HFD3_k127_5158196_24 CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000006367 114.0
HFD3_k127_5158196_25 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.00000000000000000000008751 112.0
HFD3_k127_5158196_26 TIGRFAM VWFA-related Acidobacterial domain K07114 - - 0.0000000004609 71.0
HFD3_k127_5158196_27 M61 glycyl aminopeptidase - - - 0.000000002595 70.0
HFD3_k127_5158196_28 snoRNA binding - - - 0.00000001708 61.0
HFD3_k127_5158196_29 Sh3 type 3 domain protein - - - 0.00000003913 65.0
HFD3_k127_5158196_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006605 486.0
HFD3_k127_5158196_30 - - - - 0.0000002343 60.0
HFD3_k127_5158196_31 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000001858 54.0
HFD3_k127_5158196_32 - - - - 0.000007298 50.0
HFD3_k127_5158196_4 PFAM TonB-dependent Receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 418.0
HFD3_k127_5158196_5 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 395.0
HFD3_k127_5158196_6 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005127 392.0
HFD3_k127_5158196_7 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 357.0
HFD3_k127_5158196_8 7TM receptor with intracellular metal dependent phosphohydrolase K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 357.0
HFD3_k127_5158196_9 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 350.0
HFD3_k127_5219016_0 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 482.0
HFD3_k127_5219016_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007019 340.0
HFD3_k127_5219016_10 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000007305 87.0
HFD3_k127_5219016_11 - - - - 0.00000000001051 67.0
HFD3_k127_5219016_12 Putative zinc-finger - - - 0.0000000548 59.0
HFD3_k127_5219016_13 - - - - 0.00002482 55.0
HFD3_k127_5219016_2 Domain of unknown function (DUF4118) - - - 0.000000000000000000000000000000000000000000000000000000000002291 235.0
HFD3_k127_5219016_3 uridine kinase K00876 - 2.7.1.48 0.00000000000000000000000000000000000000000000000000001452 194.0
HFD3_k127_5219016_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000002803 184.0
HFD3_k127_5219016_5 PFAM Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000001227 173.0
HFD3_k127_5219016_6 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000000000001775 171.0
HFD3_k127_5219016_7 Member of the two-component regulatory system NreB NreC involved in the control of dissimilatory nitrate nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the K07683 - 2.7.13.3 0.0000000000000000000000008715 121.0
HFD3_k127_5219016_8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.000000000000000000006255 102.0
HFD3_k127_5219016_9 Response regulator, receiver K06147 - - 0.0000000000000001474 84.0
HFD3_k127_5256522_0 Fumarate reductase flavoprotein C-term K00239 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000692 580.0
HFD3_k127_5256522_1 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 471.0
HFD3_k127_5256522_10 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000001863 259.0
HFD3_k127_5256522_11 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001586 256.0
HFD3_k127_5256522_12 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000000000000000000000000000000001611 258.0
HFD3_k127_5256522_13 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000000000553 230.0
HFD3_k127_5256522_14 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000001286 241.0
HFD3_k127_5256522_15 Sulfate ABC transporter substrate-binding protein K02048 - - 0.0000000000000000000000000000000000000000000000000000000000000003041 237.0
HFD3_k127_5256522_16 orotate phosphoribosyltransferase activity K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000005098 216.0
HFD3_k127_5256522_17 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000008986 202.0
HFD3_k127_5256522_18 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000002768 199.0
HFD3_k127_5256522_19 TIGRFAM sulfate ABC transporter, inner membrane subunit CysT K02046 - - 0.000000000000000000000000000000000000000000000000001189 194.0
HFD3_k127_5256522_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 430.0
HFD3_k127_5256522_20 PFAM glycosyl transferase family 39 - - - 0.000000000000000000000000000000000000000000000000005516 199.0
HFD3_k127_5256522_21 - - - - 0.00000000000000000000000000000000000000000000000001263 192.0
HFD3_k127_5256522_22 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.00000000000000000000000000000000000000000000004979 177.0
HFD3_k127_5256522_23 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000002142 181.0
HFD3_k127_5256522_24 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02342,K03763 - 2.7.7.7 0.00000000000000000000000000000000000000001622 163.0
HFD3_k127_5256522_25 PFAM phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.000000000000000000000000000000000000057 153.0
HFD3_k127_5256522_26 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000003189 133.0
HFD3_k127_5256522_27 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000006331 136.0
HFD3_k127_5256522_28 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000002932 112.0
HFD3_k127_5256522_29 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000000105 104.0
HFD3_k127_5256522_3 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006283 392.0
HFD3_k127_5256522_30 PFAM SNARE associated Golgi protein - - - 0.000000000000000002235 94.0
HFD3_k127_5256522_31 SNARE associated Golgi protein - - - 0.00000000000000004544 89.0
HFD3_k127_5256522_32 peptidyl-tyrosine sulfation - - - 0.0000000003233 70.0
HFD3_k127_5256522_33 - - - - 0.0000000004471 70.0
HFD3_k127_5256522_34 RDD family - - - 0.000000000857 65.0
HFD3_k127_5256522_35 chlorophyll binding - - - 0.0000003992 61.0
HFD3_k127_5256522_36 Protein of unknown function (DUF2490) - - - 0.000008486 56.0
HFD3_k127_5256522_37 of the alpha beta superfamily K06889 - - 0.0001917 53.0
HFD3_k127_5256522_4 SpoIVB peptidase S55 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 370.0
HFD3_k127_5256522_5 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005786 340.0
HFD3_k127_5256522_6 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008818 307.0
HFD3_k127_5256522_7 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004029 294.0
HFD3_k127_5256522_8 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001058 283.0
HFD3_k127_5256522_9 Oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005994 277.0
HFD3_k127_5457058_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1564.0
HFD3_k127_5457058_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1330.0
HFD3_k127_5457058_10 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 430.0
HFD3_k127_5457058_11 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006175 417.0
HFD3_k127_5457058_12 Arsenical pump-driving ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 413.0
HFD3_k127_5457058_13 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006267 388.0
HFD3_k127_5457058_14 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 391.0
HFD3_k127_5457058_15 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000862 380.0
HFD3_k127_5457058_16 ATPase associated with various cellular K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009574 375.0
HFD3_k127_5457058_17 Class II aldolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 369.0
HFD3_k127_5457058_18 CHASE3 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007119 364.0
HFD3_k127_5457058_19 Cation efflux family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 343.0
HFD3_k127_5457058_2 Phosphate acyltransferases K01897 - 6.2.1.3 7.383e-230 740.0
HFD3_k127_5457058_20 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 347.0
HFD3_k127_5457058_21 heat shock protein binding K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 336.0
HFD3_k127_5457058_22 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 350.0
HFD3_k127_5457058_23 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 325.0
HFD3_k127_5457058_24 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006633 324.0
HFD3_k127_5457058_25 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003725 302.0
HFD3_k127_5457058_26 Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001841 278.0
HFD3_k127_5457058_27 Actin K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006172 269.0
HFD3_k127_5457058_28 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000003198 225.0
HFD3_k127_5457058_29 PFAM Isochorismatase K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000000004838 203.0
HFD3_k127_5457058_3 Subtilase family - - - 6.899e-213 678.0
HFD3_k127_5457058_30 LytTr DNA-binding domain K02477 - - 0.00000000000000000000000000000000000000000000000000000001729 208.0
HFD3_k127_5457058_31 - - - - 0.0000000000000000000000000000000000000000000000000009763 205.0
HFD3_k127_5457058_32 BON domain - - - 0.000000000000000000000000000000000000000002037 164.0
HFD3_k127_5457058_33 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000008003 142.0
HFD3_k127_5457058_34 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.000000000000000000000000000000000001439 155.0
HFD3_k127_5457058_35 - - - - 0.000000000000000000000000000000000003519 143.0
HFD3_k127_5457058_36 Gas vesicle synthesis protein GvpL/GvpF - - - 0.00000000000000000000000000000000003324 147.0
HFD3_k127_5457058_37 Transcriptional regulator - - - 0.00000000000000000000000000000006026 131.0
HFD3_k127_5457058_38 Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure - - - 0.000000000000000000000000000001422 123.0
HFD3_k127_5457058_39 Gas vesicle - - - 0.00000000000000000000000000002343 121.0
HFD3_k127_5457058_4 Glycine D-amino acid oxidase (deaminating) - - - 3.886e-203 644.0
HFD3_k127_5457058_40 Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth - - - 0.00000000000000000000000001823 113.0
HFD3_k127_5457058_41 Plasmid stabilization - - - 0.000000000000000000000003667 103.0
HFD3_k127_5457058_42 Gas vesicle synthesis protein GvpL/GvpF - - - 0.00000000000000000006989 99.0
HFD3_k127_5457058_43 Sigma-70 region 2 K03088 - - 0.0000000000000000007096 93.0
HFD3_k127_5457058_44 - - - - 0.0000000000000003546 79.0
HFD3_k127_5457058_46 - - - - 0.000000000003851 67.0
HFD3_k127_5457058_47 Peptidoglycan-binding domain 1 protein - - - 0.00000000002283 72.0
HFD3_k127_5457058_48 gas vesicle protein - - - 0.00000000003915 67.0
HFD3_k127_5457058_49 Putative adhesin - - - 0.00000003242 65.0
HFD3_k127_5457058_5 Phosphoglucose isomerase K01810,K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 555.0
HFD3_k127_5457058_50 Pfam:N_methyl_2 - - - 0.000003391 56.0
HFD3_k127_5457058_52 Adenylate cyclase K01768 - 4.6.1.1 0.00002315 47.0
HFD3_k127_5457058_53 Fibronectin type iii domain protein - - - 0.0003561 48.0
HFD3_k127_5457058_6 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K01719,K13542 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,4.1.1.37,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 466.0
HFD3_k127_5457058_7 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 475.0
HFD3_k127_5457058_8 protoporphyrinogen oxidase activity K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 463.0
HFD3_k127_5457058_9 competence protein COMEC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000383 443.0
HFD3_k127_5482698_0 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 385.0
HFD3_k127_5482698_1 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000003529 165.0
HFD3_k127_5482698_10 - - - - 0.00002533 48.0
HFD3_k127_5482698_2 Glutamine cyclotransferase - - - 0.000000000000000000000000000000000003821 150.0
HFD3_k127_5482698_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000006065 139.0
HFD3_k127_5482698_4 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00000000000000000000003937 103.0
HFD3_k127_5482698_5 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - 0.00000000000000000001436 92.0
HFD3_k127_5482698_6 - - - - 0.00000000000000000189 89.0
HFD3_k127_5482698_7 transcriptional regulator K07727 - - 0.000000000005518 72.0
HFD3_k127_5482698_8 Ferredoxin K04755 - - 0.000000008705 63.0
HFD3_k127_5482698_9 phosphorelay signal transduction system - - - 0.00001245 54.0
HFD3_k127_5483382_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.0 1066.0
HFD3_k127_5483382_1 PFAM Aldo keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 432.0
HFD3_k127_5483382_2 ABC transporter, transmembrane region K18890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 323.0
HFD3_k127_5483382_3 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000005785 233.0
HFD3_k127_5483382_4 Protein of unknown function (DUF541) K09797 - - 0.00000000000000000000000000000000000000000000000000000000000003489 223.0
HFD3_k127_5483382_5 PHP domain protein - - - 0.000000000000000000000000000000000005741 151.0
HFD3_k127_5483382_6 Carboxypeptidase regulatory-like domain - - - 0.0000000006438 64.0
HFD3_k127_5483382_7 lytic transglycosylase activity K03194 - - 0.00000009662 64.0
HFD3_k127_5511157_0 ThiC-associated domain K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 3.914e-305 947.0
HFD3_k127_5511157_1 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 4.359e-295 922.0
HFD3_k127_5511157_10 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 442.0
HFD3_k127_5511157_12 Associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004807 367.0
HFD3_k127_5511157_13 PFAM Amidohydrolase 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 361.0
HFD3_k127_5511157_14 Gluconolactonase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 357.0
HFD3_k127_5511157_15 peptidase C14 caspase catalytic subunit p20 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004533 376.0
HFD3_k127_5511157_16 Psort location CytoplasmicMembrane, score 10.00 K06901 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 338.0
HFD3_k127_5511157_17 4Fe-4S double cluster binding domain K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007755 327.0
HFD3_k127_5511157_18 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 321.0
HFD3_k127_5511157_19 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 318.0
HFD3_k127_5511157_2 PFAM peptidase S9 prolyl oligopeptidase active site domain protein K01322,K01354 - 3.4.21.26,3.4.21.83 2.245e-261 823.0
HFD3_k127_5511157_20 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006495 307.0
HFD3_k127_5511157_21 oxidoreductase activity K00274 - 1.4.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002994 282.0
HFD3_k127_5511157_22 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001832 254.0
HFD3_k127_5511157_23 xanthine dehydrogenase activity K13479 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000007502 252.0
HFD3_k127_5511157_24 Stage II sporulation protein M - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006339 248.0
HFD3_k127_5511157_25 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002336 246.0
HFD3_k127_5511157_26 2 iron, 2 sulfur cluster binding K03518,K07302 - 1.2.5.3,1.3.99.16 0.000000000000000000000000000000000000000000000000000000000004348 211.0
HFD3_k127_5511157_27 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000000008761 214.0
HFD3_k127_5511157_28 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000225 207.0
HFD3_k127_5511157_29 Thioredoxin reductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000705 183.0
HFD3_k127_5511157_3 PFAM peptidase - - - 6.916e-195 623.0
HFD3_k127_5511157_30 Belongs to the allantoicase family K01477 - 3.5.3.4 0.00000000000000000000000000000000000000000002342 168.0
HFD3_k127_5511157_31 protein, possibly involved in aromatic compounds catabolism - - - 0.0000000000000000000000000000000000000000001158 163.0
HFD3_k127_5511157_32 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000002201 166.0
HFD3_k127_5511157_33 abc-type fe3 -hydroxamate transport system, periplasmic component - - - 0.00000000000000000000000000000000000000002175 156.0
HFD3_k127_5511157_34 phosphoprotein phosphatase activity K07313 - 3.1.3.16 0.000000000000000000000000000000000004197 147.0
HFD3_k127_5511157_35 Transthyretin K07127 - 3.5.2.17 0.00000000000000000000000000000000946 132.0
HFD3_k127_5511157_36 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000002929 129.0
HFD3_k127_5511157_37 - - - - 0.00000000000000000000000000001729 130.0
HFD3_k127_5511157_38 ThiS family K21029,K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000005334 119.0
HFD3_k127_5511157_39 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000001493 108.0
HFD3_k127_5511157_4 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 552.0
HFD3_k127_5511157_40 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10794 - 1.21.4.1 0.00000000000000000000007567 108.0
HFD3_k127_5511157_41 Anti-sigma-K factor rskA - - - 0.0000000000000000000006314 106.0
HFD3_k127_5511157_42 - - - - 0.00000000000003113 84.0
HFD3_k127_5511157_43 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000005245 71.0
HFD3_k127_5511157_45 integral membrane protein - - - 0.0000000000393 74.0
HFD3_k127_5511157_48 - - - - 0.00000003936 61.0
HFD3_k127_5511157_49 Domain of unknown function (DUF309) - - - 0.00000007353 62.0
HFD3_k127_5511157_5 Amidohydrolase family K01466 - 3.5.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 525.0
HFD3_k127_5511157_50 iron ion homeostasis - - - 0.0000004583 63.0
HFD3_k127_5511157_51 iron ion homeostasis - - - 0.0004786 53.0
HFD3_k127_5511157_6 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005328 510.0
HFD3_k127_5511157_7 Radical SAM superfamily K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006478 487.0
HFD3_k127_5511157_8 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005299 514.0
HFD3_k127_5511157_9 Belongs to the allantoicase family K01477 - 3.5.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009244 465.0
HFD3_k127_5525365_0 alginic acid biosynthetic process - - - 6.067e-226 764.0
HFD3_k127_5525365_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 3.379e-224 702.0
HFD3_k127_5525365_10 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000005693 196.0
HFD3_k127_5525365_11 domain protein K02674,K07004 - - 0.000000000000000000000000000000000000000482 174.0
HFD3_k127_5525365_12 oxidoreductase activity - - - 0.0000000000000000000000000000000000004909 161.0
HFD3_k127_5525365_13 serine-type endopeptidase activity K14645,K20276 - - 0.00000000000000000000001139 112.0
HFD3_k127_5525365_14 SMI1 / KNR4 family (SUKH-1) - - - 0.0000000000000000000006255 102.0
HFD3_k127_5525365_15 - - - - 0.00000000000000001522 86.0
HFD3_k127_5525365_16 Protein of unknown function (DUF1176) - - - 0.00000003274 62.0
HFD3_k127_5525365_2 Protein kinase domain K12132 - 2.7.11.1 8.215e-224 726.0
HFD3_k127_5525365_3 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007855 535.0
HFD3_k127_5525365_4 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009106 470.0
HFD3_k127_5525365_5 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004567 404.0
HFD3_k127_5525365_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005659 332.0
HFD3_k127_5525365_7 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000000000001031 223.0
HFD3_k127_5525365_8 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.000000000000000000000000000000000000000000000000000000000000005707 233.0
HFD3_k127_5525365_9 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000004142 218.0
HFD3_k127_5552384_0 cell shape determining protein MreB K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 551.0
HFD3_k127_5552384_1 PFAM Integral membrane protein TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 355.0
HFD3_k127_5552384_2 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000006871 197.0
HFD3_k127_5552384_3 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000002073 183.0
HFD3_k127_5552384_4 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000004545 134.0
HFD3_k127_5552384_5 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.00000000000000000005678 105.0
HFD3_k127_5552384_6 shape-determining protein MreD K03571 - - 0.00005983 53.0
HFD3_k127_5552384_7 FecR protein - - - 0.0009477 51.0
HFD3_k127_5559205_0 TIGRFAM carbamoyl-phosphate synthase, large subunit K01955 - 6.3.5.5 0.0 1397.0
HFD3_k127_5559205_1 Carboxypeptidase regulatory-like domain - - - 6.717e-315 1003.0
HFD3_k127_5559205_10 phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.0000000000000000000000000000000000000000000000000000002238 201.0
HFD3_k127_5559205_11 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000002191 186.0
HFD3_k127_5559205_12 Probable molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000008496 179.0
HFD3_k127_5559205_13 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000002872 179.0
HFD3_k127_5559205_14 CoA binding domain K06929 - - 0.0000000000000000000000000000000000000000000001167 175.0
HFD3_k127_5559205_15 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0050896 4.4.1.5 0.0000000000000000000000000000000000000000000006076 171.0
HFD3_k127_5559205_16 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000005257 174.0
HFD3_k127_5559205_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000946 132.0
HFD3_k127_5559205_18 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000004638 131.0
HFD3_k127_5559205_19 - - - - 0.00000000000000000001072 96.0
HFD3_k127_5559205_2 Belongs to the PstS family K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007908 420.0
HFD3_k127_5559205_20 DoxX K15977 - - 0.00000000000000005732 86.0
HFD3_k127_5559205_21 DnaJ molecular chaperone homology domain - - - 0.000000000000003089 84.0
HFD3_k127_5559205_22 Periplasmic or secreted lipoprotein - - - 0.0000000000001163 79.0
HFD3_k127_5559205_23 Transcriptional regulatory protein, C terminal - - - 0.00000000000392 75.0
HFD3_k127_5559205_24 PASTA K12132 - 2.7.11.1 0.00000001339 65.0
HFD3_k127_5559205_25 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07776 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141 - 0.000007319 55.0
HFD3_k127_5559205_26 Putative porin - - - 0.0003779 53.0
HFD3_k127_5559205_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 346.0
HFD3_k127_5559205_4 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 342.0
HFD3_k127_5559205_5 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 319.0
HFD3_k127_5559205_6 Phosphate transport system permease protein PstA K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009552 289.0
HFD3_k127_5559205_7 Histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000001997 251.0
HFD3_k127_5559205_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000002896 231.0
HFD3_k127_5559205_9 IstB-like ATP binding protein K02315 - - 0.00000000000000000000000000000000000000000000000000000003281 205.0
HFD3_k127_5562273_0 ASPIC and UnbV - - - 7.754e-212 674.0
HFD3_k127_5562273_1 Cyclomaltodextrinase, N-terminal K21575 - 3.2.1.135 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 525.0
HFD3_k127_5562273_10 - - - - 0.0000000000000000000000000001 122.0
HFD3_k127_5562273_2 CarboxypepD_reg-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004796 503.0
HFD3_k127_5562273_3 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00850,K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 306.0
HFD3_k127_5562273_4 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006749 297.0
HFD3_k127_5562273_5 PFAM ROK family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001247 269.0
HFD3_k127_5562273_6 shikimate 3-dehydrogenase (NADP+) activity K00014,K13832 GO:0000166,GO:0003674,GO:0003824,GO:0003855,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25,4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000008856 239.0
HFD3_k127_5562273_7 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000000000001043 225.0
HFD3_k127_5562273_8 TPR repeat - - - 0.00000000000000000000000000000000000000000006028 180.0
HFD3_k127_5562273_9 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.000000000000000000000000000000000000000237 153.0
HFD3_k127_5573292_0 TIGRFAM Polyketide-type polyunsaturated fatty acid synthase, PfaA K15314 - - 0.0 2014.0
HFD3_k127_5573292_1 enterobactin catabolic process - - - 4.493e-287 890.0
HFD3_k127_5573292_10 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004662 526.0
HFD3_k127_5573292_11 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 539.0
HFD3_k127_5573292_12 PFAM DNA mismatch repair protein MutS domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009428 502.0
HFD3_k127_5573292_13 Domain of unknown function (DUF4070) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 495.0
HFD3_k127_5573292_14 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003592 453.0
HFD3_k127_5573292_15 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003952 470.0
HFD3_k127_5573292_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 449.0
HFD3_k127_5573292_17 cAMP biosynthetic process K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000096 455.0
HFD3_k127_5573292_18 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 391.0
HFD3_k127_5573292_19 Transmembrane secretion effector K08225 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005898 374.0
HFD3_k127_5573292_2 amino acid - - - 6.603e-262 821.0
HFD3_k127_5573292_20 electron transport chain K00347,K03614,K21162,K21163 - 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006304 363.0
HFD3_k127_5573292_21 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008348 364.0
HFD3_k127_5573292_22 ThiF family K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 351.0
HFD3_k127_5573292_23 PFAM FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006702 338.0
HFD3_k127_5573292_24 Leucine-rich repeat K13730 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 357.0
HFD3_k127_5573292_25 including yeast histone deacetylase and acetoin utilization protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009545 305.0
HFD3_k127_5573292_26 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009357 310.0
HFD3_k127_5573292_27 Protein of unknown function (DUF1702) K21161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005111 293.0
HFD3_k127_5573292_28 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006448 292.0
HFD3_k127_5573292_29 Protease prsW family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001294 291.0
HFD3_k127_5573292_3 amino acid - - - 2.736e-257 809.0
HFD3_k127_5573292_30 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002657 285.0
HFD3_k127_5573292_31 Oxidoreductase activity. It is involved in the biological process described with metabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000693 285.0
HFD3_k127_5573292_32 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003198 278.0
HFD3_k127_5573292_33 RNA 2'-O ribose methyltransferase substrate binding K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000003076 255.0
HFD3_k127_5573292_34 3-demethylubiquinone-9 3-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005208 240.0
HFD3_k127_5573292_35 ATP dependent DNA ligase domain K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000009255 245.0
HFD3_k127_5573292_36 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000001072 239.0
HFD3_k127_5573292_37 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000000000000000000000000000000000002589 237.0
HFD3_k127_5573292_38 Histidine kinase K08082 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000009411 241.0
HFD3_k127_5573292_39 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000001162 214.0
HFD3_k127_5573292_4 phosphorylase K00688 - 2.4.1.1 6.354e-247 781.0
HFD3_k127_5573292_40 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000002527 214.0
HFD3_k127_5573292_41 Appr-1'-p processing enzyme - - - 0.00000000000000000000000000000000000000000000000000000000009186 210.0
HFD3_k127_5573292_42 - - - - 0.0000000000000000000000000000000000000000000000000000001314 207.0
HFD3_k127_5573292_43 PFAM helix-turn-helix- domain containing protein AraC type - - - 0.0000000000000000000000000000000000000000000000000000009782 203.0
HFD3_k127_5573292_44 Thioesterase-like superfamily K15315 - - 0.000000000000000000000000000000000000000000000000000001098 195.0
HFD3_k127_5573292_45 chaperone-mediated protein folding - - - 0.000000000000000000000000000000000000000000000000000002466 214.0
HFD3_k127_5573292_46 tRNA 3'-trailer cleavage K00784,K01120 - 3.1.26.11,3.1.4.17 0.00000000000000000000000000000000000000000000000000004121 196.0
HFD3_k127_5573292_47 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K07291 - 2.7.8.34 0.0000000000000000000000000000000000000000000000000003931 196.0
HFD3_k127_5573292_48 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000546 207.0
HFD3_k127_5573292_49 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000009029 183.0
HFD3_k127_5573292_5 ASPIC and UnbV K21162 - - 1.794e-241 767.0
HFD3_k127_5573292_50 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000207 187.0
HFD3_k127_5573292_51 actin binding - - - 0.00000000000000000000000000000000000000000003506 178.0
HFD3_k127_5573292_52 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000004424 177.0
HFD3_k127_5573292_53 serine-type endopeptidase activity - - - 0.0000000000000000000000000000000000000000004733 168.0
HFD3_k127_5573292_54 PspA/IM30 family K03969 - - 0.0000000000000000000000000000000000000001589 159.0
HFD3_k127_5573292_55 aminoglycoside hydroxyurea antibiotic resistance kinase K04343 - 2.7.1.72 0.00000000000000000000000000000000000000038 161.0
HFD3_k127_5573292_56 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000000000000006687 145.0
HFD3_k127_5573292_58 Protein of unknown function (DUF1572) - - - 0.000000000000000000000000000000000001499 144.0
HFD3_k127_5573292_59 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07709 - 2.7.13.3 0.000000000000000000000000000000000004059 156.0
HFD3_k127_5573292_6 Elongation factor G, domain IV K02355 - - 4.395e-227 726.0
HFD3_k127_5573292_60 Methyltransferase domain - - - 0.00000000000000000000000000000000007297 144.0
HFD3_k127_5573292_61 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.00000000000000000000000000000002357 130.0
HFD3_k127_5573292_62 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000177 128.0
HFD3_k127_5573292_63 Probable zinc-ribbon domain - - - 0.000000000000000000000000000007962 122.0
HFD3_k127_5573292_64 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.0000000000000000000000000003881 117.0
HFD3_k127_5573292_65 ComF family K02242 - - 0.000000000000000000000000003599 121.0
HFD3_k127_5573292_66 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000004052 115.0
HFD3_k127_5573292_67 - - - - 0.000000000000000000000000004223 112.0
HFD3_k127_5573292_68 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000003393 116.0
HFD3_k127_5573292_69 - - - - 0.0000000000000000000000007894 114.0
HFD3_k127_5573292_7 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 4.31e-197 646.0
HFD3_k127_5573292_70 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000001635 106.0
HFD3_k127_5573292_71 Protein of unknown function (DUF971) - - - 0.000000000000000000000004697 104.0
HFD3_k127_5573292_72 Uncharacterized conserved protein (DUF2203) - - - 0.00000000000000000000003391 103.0
HFD3_k127_5573292_73 NIPSNAP - - - 0.0000000000000000000001081 101.0
HFD3_k127_5573292_74 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000009366 104.0
HFD3_k127_5573292_75 Protein of unknown function (DUF2847) - - - 0.0000000000000000009924 91.0
HFD3_k127_5573292_76 Domain of unknown function (DUF4384) - - - 0.000000000000000008926 94.0
HFD3_k127_5573292_77 - - - - 0.0000000000000008575 88.0
HFD3_k127_5573292_78 Ribosomal RNA adenine dimethylase K05929 - 2.1.1.103 0.0000000000000009831 88.0
HFD3_k127_5573292_8 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006098 574.0
HFD3_k127_5573292_80 - - - - 0.000000005175 60.0
HFD3_k127_5573292_81 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000009819 52.0
HFD3_k127_5573292_82 ArsR family transcriptional regulator - - - 0.000001991 59.0
HFD3_k127_5573292_83 transcriptional regulator - - - 0.0001485 52.0
HFD3_k127_5573292_84 BON domain K04065 - - 0.0004357 50.0
HFD3_k127_5573292_85 RNA polymerase-associated protein CTR9 homolog K15176 GO:0000122,GO:0000428,GO:0000785,GO:0000993,GO:0001098,GO:0001099,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0006325,GO:0006355,GO:0006357,GO:0006464,GO:0006479,GO:0006807,GO:0006996,GO:0008023,GO:0008150,GO:0008152,GO:0008213,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009909,GO:0009910,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010638,GO:0016020,GO:0016043,GO:0016569,GO:0016570,GO:0016571,GO:0016591,GO:0016593,GO:0018022,GO:0018023,GO:0018193,GO:0018205,GO:0019219,GO:0019222,GO:0019538,GO:0019899,GO:0030880,GO:0031056,GO:0031058,GO:0031060,GO:0031062,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031399,GO:0031401,GO:0031974,GO:0031981,GO:0032259,GO:0032268,GO:0032270,GO:0032784,GO:0032786,GO:0032968,GO:0032991,GO:0033043,GO:0033044,GO:0034243,GO:0034968,GO:0035327,GO:0036211,GO:0043170,GO:0043175,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0044877,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045944,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048580,GO:0048581,GO:0048831,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051254,GO:0051276,GO:0051568,GO:0051569,GO:0051571,GO:0055029,GO:0060255,GO:0061695,GO:0065007,GO:0070013,GO:0070063,GO:0071704,GO:0071840,GO:0080090,GO:0080182,GO:1901564,GO:1902275,GO:1902494,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1905269,GO:1990234,GO:2000026,GO:2000112,GO:2000113,GO:2000241,GO:2000242,GO:2001141,GO:2001252 - 0.0006987 52.0
HFD3_k127_5573292_9 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 561.0
HFD3_k127_5574493_0 Multicopper oxidase - - - 0.0 1262.0
HFD3_k127_5574493_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000633 516.0
HFD3_k127_5574493_10 glycosyltransferase involved in LPS biosynthesis K07270 - - 0.00000000000000000000000000000000000000000001158 177.0
HFD3_k127_5574493_11 SCO1 SenC K07152 - - 0.0000000000000000000000000000000000000000000526 169.0
HFD3_k127_5574493_12 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000000000000000000000000000002596 153.0
HFD3_k127_5574493_13 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000003332 144.0
HFD3_k127_5574493_14 Endoribonuclease L-PSP - - - 0.000000000000000000000000000002652 124.0
HFD3_k127_5574493_15 dioxygenase activity - - - 0.0000000000000000000000000007738 123.0
HFD3_k127_5574493_16 Glycosyltransferase like family 2 - - - 0.000000000000000000000000009975 121.0
HFD3_k127_5574493_17 Low molecular weight phosphotyrosine protein phosphatase K01104,K20201 - 3.1.3.48,3.9.1.2 0.0000000000000000000486 104.0
HFD3_k127_5574493_18 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000004262 83.0
HFD3_k127_5574493_19 Uncharacterized ACR, YdiU/UPF0061 family - - - 0.00000000002623 77.0
HFD3_k127_5574493_2 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 446.0
HFD3_k127_5574493_20 - - - - 0.00000000003637 69.0
HFD3_k127_5574493_21 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000109 69.0
HFD3_k127_5574493_22 2OG-Fe(II) oxygenase superfamily K15429 - 2.1.1.228 0.00000003414 64.0
HFD3_k127_5574493_23 Cation transport ATPase K17686 - 3.6.3.54 0.000008002 56.0
HFD3_k127_5574493_24 - - - - 0.0001077 50.0
HFD3_k127_5574493_25 Methyltransferase domain - - - 0.0001613 52.0
HFD3_k127_5574493_26 Glycosyltransferase family 92 - - - 0.0002347 52.0
HFD3_k127_5574493_3 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 334.0
HFD3_k127_5574493_4 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 317.0
HFD3_k127_5574493_5 beta-fructofuranosidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 312.0
HFD3_k127_5574493_7 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate - - - 0.00000000000000000000000000000000000000000000000000000000000000000004139 249.0
HFD3_k127_5574493_8 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000005114 182.0
HFD3_k127_5574493_9 SCO1/SenC K07152,K08976 - - 0.000000000000000000000000000000000000000000004125 167.0
HFD3_k127_5596609_0 Aldehyde oxidase and xanthine dehydrogenase a b hammerhead K03520,K11177 - 1.17.1.4,1.2.5.3 0.0 1318.0
HFD3_k127_5596609_1 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 4.647e-227 719.0
HFD3_k127_5596609_10 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 360.0
HFD3_k127_5596609_11 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009899 345.0
HFD3_k127_5596609_12 VWA domain containing CoxE-like protein K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 346.0
HFD3_k127_5596609_13 Associated with various cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 310.0
HFD3_k127_5596609_14 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 299.0
HFD3_k127_5596609_15 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 287.0
HFD3_k127_5596609_16 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002901 284.0
HFD3_k127_5596609_17 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000508 290.0
HFD3_k127_5596609_18 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001154 262.0
HFD3_k127_5596609_19 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001214 261.0
HFD3_k127_5596609_2 Ftsk_gamma K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 632.0
HFD3_k127_5596609_20 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000001311 265.0
HFD3_k127_5596609_21 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000001443 259.0
HFD3_k127_5596609_22 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001577 258.0
HFD3_k127_5596609_23 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000001561 245.0
HFD3_k127_5596609_24 COGs COG1975 Xanthine and CO dehydrogenase maturation factor XdhC CoxF family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000001823 236.0
HFD3_k127_5596609_25 ABC-type molybdate transport system, permease component K02018 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000003443 223.0
HFD3_k127_5596609_26 XdhC and CoxI family K07402 - - 0.000000000000000000000000000000000000000000000000000000003729 212.0
HFD3_k127_5596609_27 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000005384 207.0
HFD3_k127_5596609_28 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000001387 172.0
HFD3_k127_5596609_29 Carbon monoxide dehydrogenase subunit G (CoxG) - - - 0.000000000000000000000000000000000000000004337 161.0
HFD3_k127_5596609_3 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 559.0
HFD3_k127_5596609_30 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.00000000000000000000000000000000000000001299 160.0
HFD3_k127_5596609_31 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000006226 156.0
HFD3_k127_5596609_32 outer membrane autotransporter barrel domain protein - - - 0.00000000000000000000000000000000001812 146.0
HFD3_k127_5596609_33 SUF system FeS assembly protein, NifU family K04488 - - 0.000000000000000000000000000000001051 134.0
HFD3_k127_5596609_34 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000003282 137.0
HFD3_k127_5596609_35 Cysteine dioxygenase type I K00456 - 1.13.11.20 0.0000000000000000000002271 106.0
HFD3_k127_5596609_36 SPTR ATPase associated with various cellular activities AAA_3 - - - 0.000000000000000001901 86.0
HFD3_k127_5596609_37 - - - - 0.000000000000000005991 84.0
HFD3_k127_5596609_38 - - - - 0.0008399 49.0
HFD3_k127_5596609_4 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007473 493.0
HFD3_k127_5596609_5 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 489.0
HFD3_k127_5596609_6 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009761 479.0
HFD3_k127_5596609_7 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 405.0
HFD3_k127_5596609_8 Type II secretion system (T2SS), protein F K02455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 398.0
HFD3_k127_5596609_9 UDP-glucoronosyl and UDP-glucosyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007306 385.0
HFD3_k127_5606393_0 AlkA N-terminal domain K13529 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 437.0
HFD3_k127_5606393_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001365 263.0
HFD3_k127_5606393_2 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000006799 210.0
HFD3_k127_5606393_3 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000001377 129.0
HFD3_k127_5606393_4 - - - - 0.00000000000000000000000000005663 123.0
HFD3_k127_5606393_5 Copper-transporting ATPase K17686 GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0006950,GO:0008150,GO:0008324,GO:0009636,GO:0010035,GO:0010038,GO:0010273,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046688,GO:0046873,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0061687,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0097501,GO:0098655,GO:0098660,GO:0098662,GO:0098754,GO:0099131,GO:0099132,GO:1990169 3.6.3.54 0.000002943 53.0
HFD3_k127_5606393_6 Transcriptional regulator K07506 - - 0.0004827 44.0
HFD3_k127_562492_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1290.0
HFD3_k127_562492_1 Phosphoglucomutase K01835 - 5.4.2.2 3.539e-285 882.0
HFD3_k127_562492_10 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 362.0
HFD3_k127_562492_11 phosphoglycolate phosphatase activity K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 348.0
HFD3_k127_562492_12 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 355.0
HFD3_k127_562492_13 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 309.0
HFD3_k127_562492_14 CRP FNR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 300.0
HFD3_k127_562492_15 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001042 289.0
HFD3_k127_562492_16 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001967 295.0
HFD3_k127_562492_17 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007373 282.0
HFD3_k127_562492_18 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002362 302.0
HFD3_k127_562492_19 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005639 286.0
HFD3_k127_562492_2 silver ion transport K15726 - - 1.736e-273 874.0
HFD3_k127_562492_20 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006215 277.0
HFD3_k127_562492_21 NADPH-dependent FMN reductase K19784 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001434 259.0
HFD3_k127_562492_22 Crp-like helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000154 253.0
HFD3_k127_562492_23 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000839 252.0
HFD3_k127_562492_24 Barrel-sandwich domain of CusB or HlyD membrane-fusion K18302 - - 0.000000000000000000000000000000000000000000000000000000000000000000001933 251.0
HFD3_k127_562492_25 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000002866 219.0
HFD3_k127_562492_26 Tetratricopeptide repeats - - - 0.00000000000000000000000000000000000000000000000000000000000003389 245.0
HFD3_k127_562492_27 - - - - 0.00000000000000000000000000000000000000000000000000000000003591 209.0
HFD3_k127_562492_28 mannose-ethanolamine phosphotransferase activity - - - 0.000000000000000000000000000000000000000000000000000002425 214.0
HFD3_k127_562492_29 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.00000000000000000000000000000000000000000000000000001613 204.0
HFD3_k127_562492_3 Tetratricopeptide repeat - - - 2.98e-242 790.0
HFD3_k127_562492_30 beta-fructofuranosidase activity - - - 0.0000000000000000000000000000000000000000000000000005711 204.0
HFD3_k127_562492_31 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K15725 - - 0.0000000000000000000000000000000000000000000000002615 194.0
HFD3_k127_562492_32 regulatory, ligand-binding protein related to C-terminal domains of K channels K07228 - - 0.0000000000000000000000000000000000000000000000009479 182.0
HFD3_k127_562492_33 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000005968 179.0
HFD3_k127_562492_34 cytochrome - - - 0.000000000000000000000000000000000000000000006871 169.0
HFD3_k127_562492_35 - - - - 0.0000000000000000000000000000000000000129 149.0
HFD3_k127_562492_36 MerR, DNA binding - - - 0.000000000000000000000000000000000003699 143.0
HFD3_k127_562492_37 - - - - 0.00000000000000000000406 100.0
HFD3_k127_562492_38 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000000000009783 91.0
HFD3_k127_562492_39 Peptidase family M23 - - - 0.00000000000000002556 96.0
HFD3_k127_562492_4 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 601.0
HFD3_k127_562492_40 - - - - 0.00000000000004705 73.0
HFD3_k127_562492_41 Tetratricopeptide repeat - - - 0.0000000000001518 84.0
HFD3_k127_562492_42 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.00000000008382 65.0
HFD3_k127_562492_43 SnoaL-like domain - - - 0.0000000006516 68.0
HFD3_k127_562492_44 - - - - 0.000000008115 68.0
HFD3_k127_562492_45 spectrin binding - - - 0.000003761 59.0
HFD3_k127_562492_47 tetratricopeptide repeat - - - 0.0002302 54.0
HFD3_k127_562492_48 UPF0126 domain - - - 0.0004132 43.0
HFD3_k127_562492_5 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004141 598.0
HFD3_k127_562492_6 Sodium/hydrogen exchanger family K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 478.0
HFD3_k127_562492_7 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 473.0
HFD3_k127_562492_8 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 446.0
HFD3_k127_562492_9 dioxygenase K15777 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0046566,GO:0051213,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 387.0
HFD3_k127_562545_0 PFAM Alcohol dehydrogenase - - - 3.074e-204 642.0
HFD3_k127_562545_1 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 584.0
HFD3_k127_562545_10 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 338.0
HFD3_k127_562545_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005771 303.0
HFD3_k127_562545_12 Protein of unknown function (DUF434) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002445 266.0
HFD3_k127_562545_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007455 267.0
HFD3_k127_562545_14 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005553 278.0
HFD3_k127_562545_15 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000003592 223.0
HFD3_k127_562545_16 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000003629 216.0
HFD3_k127_562545_17 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000008768 198.0
HFD3_k127_562545_18 PFAM ATP-binding region, ATPase domain protein - - - 0.000000000000000000000000000000000286 149.0
HFD3_k127_562545_19 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000123 129.0
HFD3_k127_562545_2 electron transfer activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 562.0
HFD3_k127_562545_20 cellulose binding - - - 0.00000000000000000000003623 117.0
HFD3_k127_562545_21 Two component transcriptional regulator, winged helix family - - - 0.000000000000000001569 91.0
HFD3_k127_562545_22 PEP-CTERM motif - - - 0.00000000000000001884 91.0
HFD3_k127_562545_23 domain protein K01179,K12567,K20276,K21449 - 2.7.11.1,3.2.1.4 0.00000000000001028 90.0
HFD3_k127_562545_24 YcxB-like protein - - - 0.00000000000003513 81.0
HFD3_k127_562545_26 Membrane - - - 0.0000000006746 67.0
HFD3_k127_562545_27 COG3209 Rhs family protein - - - 0.0000001129 64.0
HFD3_k127_562545_28 guanyl-nucleotide exchange factor activity K20276 - - 0.0000001136 66.0
HFD3_k127_562545_29 Clostripain family - - - 0.0000002248 64.0
HFD3_k127_562545_3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 524.0
HFD3_k127_562545_30 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.0003284 55.0
HFD3_k127_562545_31 Dienelactone hydrolase family - - - 0.0004192 48.0
HFD3_k127_562545_4 Xaa-Pro aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 462.0
HFD3_k127_562545_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004051 478.0
HFD3_k127_562545_6 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 426.0
HFD3_k127_562545_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009691 433.0
HFD3_k127_562545_8 response regulator receiver K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005191 395.0
HFD3_k127_562545_9 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K21310 - 2.1.1.334 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 334.0
HFD3_k127_5633449_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 568.0
HFD3_k127_5633449_1 pyrroloquinoline quinone binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 547.0
HFD3_k127_5633449_10 PFAM CHRD domain containing protein - - - 0.0000000000003788 84.0
HFD3_k127_5633449_11 Reeler domain - - - 0.00000000009312 76.0
HFD3_k127_5633449_12 Proprotein convertase P-domain - - - 0.000000005777 70.0
HFD3_k127_5633449_2 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 393.0
HFD3_k127_5633449_3 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006747 337.0
HFD3_k127_5633449_4 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 320.0
HFD3_k127_5633449_5 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 300.0
HFD3_k127_5633449_6 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 310.0
HFD3_k127_5633449_7 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005019 257.0
HFD3_k127_5633449_9 Domain of unknown function (DUF4347) - - - 0.00000000000005515 87.0
HFD3_k127_5649002_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000631 556.0
HFD3_k127_5649002_1 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 434.0
HFD3_k127_5649002_2 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001956 252.0
HFD3_k127_5649002_3 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.0000000000000000000000000000000000000000000000001627 178.0
HFD3_k127_5649002_4 Large extracellular alpha-helical protein K06894 - - 0.0000000000000000000000000000000000000000005835 164.0
HFD3_k127_566746_0 Pyrrolo-quinoline quinone K00114 - 1.1.2.8 5.454e-294 912.0
HFD3_k127_566746_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K17223 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009009 329.0
HFD3_k127_566746_2 PFAM extracellular solute-binding protein, family 3 K16254 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007163 321.0
HFD3_k127_566746_3 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008581 276.0
HFD3_k127_566746_4 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.000000000000000000000000000000000000000003177 162.0
HFD3_k127_5694407_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 505.0
HFD3_k127_5694407_1 Fatty acid desaturase K00508 - 1.14.19.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 452.0
HFD3_k127_5694407_10 - - - - 0.0001075 47.0
HFD3_k127_5694407_11 - - - - 0.0006253 47.0
HFD3_k127_5694407_2 SMART HTH transcriptional regulator, Crp - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 294.0
HFD3_k127_5694407_3 Crp-like helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001641 247.0
HFD3_k127_5694407_4 Domain of unknown function (DUF4440) - - - 0.00000000000000000000000000000000000000325 151.0
HFD3_k127_5694407_5 RNA recognition motif - - - 0.00000000000000000000000000000001295 130.0
HFD3_k127_5694407_6 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000000000001032 107.0
HFD3_k127_5694407_7 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - 0.00000000000000000002278 92.0
HFD3_k127_5694407_8 Cupin 2, conserved barrel - - - 0.0000000003787 61.0
HFD3_k127_5694407_9 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000006682 60.0
HFD3_k127_5696103_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006918 342.0
HFD3_k127_5696103_1 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009567 285.0
HFD3_k127_5696103_2 Conserved repeat domain - - - 0.0000000000000000000000000000000000000000000000000003678 209.0
HFD3_k127_5696103_3 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000000000000000000000000000003876 201.0
HFD3_k127_5696103_4 response regulator K07685 - - 0.0000000000000000000000000000000000000000000001277 175.0
HFD3_k127_5696103_5 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000405 166.0
HFD3_k127_5696103_6 oxidoreductase activity - - - 0.000000000000000008727 99.0
HFD3_k127_5708789_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 648.0
HFD3_k127_5708789_1 Belongs to the glycosyl hydrolase 28 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007925 612.0
HFD3_k127_5708789_2 Pectic acid lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 424.0
HFD3_k127_5708789_3 Pectinesterase K01051 - 3.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000001368 284.0
HFD3_k127_571205_0 Holliday junction DNA helicase ruvB C-terminus K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 431.0
HFD3_k127_571205_1 ZIP Zinc transporter K07238,K11021,K16267 - - 0.000000000000000000000000000000000000000000000000000000000001143 218.0
HFD3_k127_571205_10 TPM domain K06872 - - 0.0000000000000000000000003003 116.0
HFD3_k127_571205_11 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.000000000000000000000003548 104.0
HFD3_k127_571205_12 Ethanolamine utilisation protein EutN/carboxysome K04028 - - 0.000000004682 61.0
HFD3_k127_571205_2 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000001116 213.0
HFD3_k127_571205_3 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000001942 190.0
HFD3_k127_571205_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000001079 184.0
HFD3_k127_571205_5 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000000000000000002868 180.0
HFD3_k127_571205_6 LemA family K03744 - - 0.00000000000000000000000000000000000000000002449 168.0
HFD3_k127_571205_7 nucleotidyltransferase activity - - - 0.00000000000000000000000000000000000757 147.0
HFD3_k127_571205_8 BMC K04027 - - 0.0000000000000000000000000000000001892 133.0
HFD3_k127_571205_9 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.0000000000000000000000000005549 115.0
HFD3_k127_5759197_0 Male sterility protein K01897 - 6.2.1.3 0.0 1305.0
HFD3_k127_5759197_1 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 2.389e-304 952.0
HFD3_k127_5759197_10 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000004163 254.0
HFD3_k127_5759197_11 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001573 248.0
HFD3_k127_5759197_12 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.000000000000000000000000000000000000000000000000000000000000008016 226.0
HFD3_k127_5759197_13 aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000009 208.0
HFD3_k127_5759197_14 Heat shock protein DnaJ domain protein - - - 0.0000000000000000000000000000000000000000000003895 181.0
HFD3_k127_5759197_15 GDP-mannose mannosyl hydrolase activity K01858,K03207,K03574 - 3.6.1.55,5.5.1.4 0.00000000000000000000000000000000000000000001475 168.0
HFD3_k127_5759197_16 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000001894 172.0
HFD3_k127_5759197_17 PFAM carbon monoxide dehydrogenase subunit G K09386 - - 0.0000000000000000000000000000000000004095 146.0
HFD3_k127_5759197_18 Tetratricopeptide repeat - - - 0.000000000000000000000000000000006312 138.0
HFD3_k127_5759197_19 peptidoglycan catabolic process - - - 0.000000000000000000000000000007728 126.0
HFD3_k127_5759197_2 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 3.997e-287 910.0
HFD3_k127_5759197_21 - - - - 0.0000000000000000003604 94.0
HFD3_k127_5759197_22 methyltransferase - - - 0.0000000000000002536 89.0
HFD3_k127_5759197_23 Peptidase family S41 - - - 0.000004628 60.0
HFD3_k127_5759197_3 Domain of unknown function (DUF2088) - - - 7.893e-225 709.0
HFD3_k127_5759197_4 Tetratricopeptide repeat - - - 1.821e-196 629.0
HFD3_k127_5759197_5 peptidase M24B X-Pro dipeptidase aminopeptidase domain protein K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 450.0
HFD3_k127_5759197_6 SMART tyrosine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005553 373.0
HFD3_k127_5759197_7 Methionine synthase K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 307.0
HFD3_k127_5759197_8 epimerase dehydratase K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 307.0
HFD3_k127_5759197_9 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 288.0
HFD3_k127_5770971_0 TIGRFAM amino acid adenylation domain - - - 0.0 1277.0
HFD3_k127_5770971_1 PEP-utilising enzyme, mobile domain - - - 0.0 1052.0
HFD3_k127_5770971_10 C-terminal, D2-small domain, of ClpB protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 458.0
HFD3_k127_5770971_11 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 451.0
HFD3_k127_5770971_12 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 447.0
HFD3_k127_5770971_13 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005515 413.0
HFD3_k127_5770971_14 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000081 403.0
HFD3_k127_5770971_15 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 352.0
HFD3_k127_5770971_16 Ornithine cyclodeaminase/mu-crystallin family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006669 327.0
HFD3_k127_5770971_17 PFAM Phosphoribosyl transferase domain K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001267 271.0
HFD3_k127_5770971_18 DNA-directed DNA polymerase activity K02347,K03581,K04477 - 3.1.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005071 273.0
HFD3_k127_5770971_19 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002598 274.0
HFD3_k127_5770971_2 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 3.684e-312 979.0
HFD3_k127_5770971_20 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003494 265.0
HFD3_k127_5770971_21 phosphoribosyltransferase K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001006 255.0
HFD3_k127_5770971_22 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000002151 250.0
HFD3_k127_5770971_23 D,d-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000000000000001175 223.0
HFD3_k127_5770971_24 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000002477 220.0
HFD3_k127_5770971_25 lipopolysaccharide heptosyltransferase K02841,K02843 - - 0.0000000000000000000000000000000000000000000000000000000165 210.0
HFD3_k127_5770971_26 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000006816 185.0
HFD3_k127_5770971_27 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000000000007681 185.0
HFD3_k127_5770971_28 PFAM Nickel cobalt transporter, high-affinity - - - 0.0000000000000000000000000000000000000000000000008053 183.0
HFD3_k127_5770971_29 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000423 176.0
HFD3_k127_5770971_3 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 1.805e-258 805.0
HFD3_k127_5770971_30 Chloramphenicol acetyltransferase K19271 - 2.3.1.28 0.0000000000000000000000000000000000000000000001135 175.0
HFD3_k127_5770971_31 Ankyrin repeat K06867 - - 0.0000000000000000000000000000000000000000000001277 175.0
HFD3_k127_5770971_32 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000000000000000000000002175 161.0
HFD3_k127_5770971_33 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000002249 165.0
HFD3_k127_5770971_34 Domain of unknown function (DUF4252) - - - 0.00000000000000000000000000000000000000003346 159.0
HFD3_k127_5770971_35 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000000006101 155.0
HFD3_k127_5770971_36 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000002462 144.0
HFD3_k127_5770971_37 Glycosyl hydrolase family 9 K01179 - 3.2.1.4 0.0000000000000000000000000004575 133.0
HFD3_k127_5770971_38 Patatin-like phospholipase K07001 - - 0.00000000000000000000000003917 117.0
HFD3_k127_5770971_39 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K13819 - - 0.000000000000000000000001094 107.0
HFD3_k127_5770971_4 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 3.648e-214 675.0
HFD3_k127_5770971_40 helix_turn_helix, arabinose operon control protein K07506 - - 0.000000000000000000000002449 115.0
HFD3_k127_5770971_41 ribosomal large subunit export from nucleus - - - 0.000000000000000000001393 101.0
HFD3_k127_5770971_42 Polysaccharide biosynthesis protein K12454 - 5.1.3.10 0.000000000000000000008426 104.0
HFD3_k127_5770971_43 multi-organism process K03195 - - 0.00000000000004722 84.0
HFD3_k127_5770971_44 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.000000000000137 81.0
HFD3_k127_5770971_45 Protein of unknown function (DUF3108) - - - 0.000000000001603 78.0
HFD3_k127_5770971_46 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000001523 70.0
HFD3_k127_5770971_47 - - - - 0.000000002709 64.0
HFD3_k127_5770971_48 signal transduction histidine kinase - - - 0.00000000291 66.0
HFD3_k127_5770971_49 HEAT repeat - - - 0.0000001274 62.0
HFD3_k127_5770971_5 Erythromycin esterase - - - 2.101e-199 629.0
HFD3_k127_5770971_50 Family of unknown function (DUF5335) - - - 0.0000006982 56.0
HFD3_k127_5770971_52 - - - - 0.00004455 53.0
HFD3_k127_5770971_53 VWA domain containing CoxE-like protein - - - 0.0001084 54.0
HFD3_k127_5770971_54 Domain of unknown function (DUF374) K02527,K09778 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0002752 52.0
HFD3_k127_5770971_6 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 604.0
HFD3_k127_5770971_7 sequence-specific DNA binding K01697,K01738 GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363 2.5.1.47,4.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 541.0
HFD3_k127_5770971_8 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 526.0
HFD3_k127_5770971_9 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000509 516.0
HFD3_k127_5820914_0 Protein of unknown function (DUF763) K09003 - - 1.981e-195 615.0
HFD3_k127_5820914_1 Vault protein inter-alpha-trypsin domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 592.0
HFD3_k127_5820914_10 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 323.0
HFD3_k127_5820914_11 transporter, permease K02033,K15581 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009179 310.0
HFD3_k127_5820914_12 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004723 264.0
HFD3_k127_5820914_13 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000002701 248.0
HFD3_k127_5820914_14 Methyltransferase domain K00588 - 2.1.1.104 0.0000000000000000000000000000000000000000000000000000000000000004038 226.0
HFD3_k127_5820914_15 response regulator receiver K02483,K07658 - - 0.000000000000000000000000000000000000000000000000000001799 199.0
HFD3_k127_5820914_16 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000001659 198.0
HFD3_k127_5820914_17 DinB family - - - 0.000000000000000000000000000000000000000000000000556 180.0
HFD3_k127_5820914_18 Cupin domain - - - 0.00000000000000000000000000000000000000000000001526 173.0
HFD3_k127_5820914_19 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000005818 187.0
HFD3_k127_5820914_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007275 527.0
HFD3_k127_5820914_20 HD domain - - - 0.000000000000000000000000000000000000000000000634 182.0
HFD3_k127_5820914_21 PFAM penicillin-binding protein transpeptidase K05364 - - 0.000000000000000000000000000000000000000002095 176.0
HFD3_k127_5820914_22 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000001035 169.0
HFD3_k127_5820914_23 Protein tyrosine kinase K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.000000000000000000000000000000000003338 155.0
HFD3_k127_5820914_24 Belongs to the SEDS family K03588 GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136 - 0.0000000000000000000000000000000002238 150.0
HFD3_k127_5820914_25 serine-type endopeptidase activity K14645,K20276 - - 0.0000000000000000000000000000001709 130.0
HFD3_k127_5820914_26 tigr00255 - - - 0.0000000000000000000000009832 110.0
HFD3_k127_5820914_27 Belongs to the ompA family - - - 0.00000000000000000000001598 113.0
HFD3_k127_5820914_28 sigma factor antagonist activity K04757 - 2.7.11.1 0.000000000001767 81.0
HFD3_k127_5820914_29 (FHA) domain - - - 0.00000000002698 74.0
HFD3_k127_5820914_3 ABC transporter K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 479.0
HFD3_k127_5820914_31 Protein of unknown function (DUF2662) - - - 0.000001366 59.0
HFD3_k127_5820914_32 STAS domain K06378 - - 0.000004126 54.0
HFD3_k127_5820914_4 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 463.0
HFD3_k127_5820914_5 ATPases associated with a variety of cellular activities K10823,K10824 - 3.6.3.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 445.0
HFD3_k127_5820914_6 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 443.0
HFD3_k127_5820914_7 Belongs to the ABC transporter superfamily K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 421.0
HFD3_k127_5820914_8 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 392.0
HFD3_k127_5820914_9 'ABC-type dipeptide oligopeptide nickel transport K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 355.0
HFD3_k127_5839603_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 4.486e-241 753.0
HFD3_k127_5839603_1 Protein of unknown function (DUF1254) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 616.0
HFD3_k127_5839603_10 Conserved Protein - - - 0.000000000000001181 90.0
HFD3_k127_5839603_11 Fatty acid desaturase K00508 - 1.14.19.3 0.00000000000002307 75.0
HFD3_k127_5839603_12 - - - - 0.0000000000002228 70.0
HFD3_k127_5839603_13 Subtilase family - - - 0.0000000002167 72.0
HFD3_k127_5839603_16 TonB-dependent receptor - - - 0.0000001793 57.0
HFD3_k127_5839603_18 Phage integrase family - - - 0.00003175 51.0
HFD3_k127_5839603_2 Transcriptional regulator, Crp Fnr family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 300.0
HFD3_k127_5839603_3 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002583 275.0
HFD3_k127_5839603_4 Cyclin-dependent kinase inhibitor 3 (CDKN3) - - - 0.0000000000000000000000000000000000000000005283 162.0
HFD3_k127_5839603_5 light absorption K06893 - - 0.00000000000000000000000000000000000000009552 156.0
HFD3_k127_5839603_6 cheY-homologous receiver domain - - - 0.000000000000000000003563 100.0
HFD3_k127_5839603_7 Nacht domain - - - 0.000000000000000005796 86.0
HFD3_k127_5839603_8 ECF sigma factor K03088 - - 0.000000000000000006992 91.0
HFD3_k127_5839603_9 DEAD-like helicases superfamily - - - 0.0000000000000007169 78.0
HFD3_k127_5842189_0 PFAM Type II secretion system protein E K02652 - - 7.895e-217 686.0
HFD3_k127_5842189_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 3.293e-211 666.0
HFD3_k127_5842189_10 Aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006533 455.0
HFD3_k127_5842189_11 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850,K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 411.0
HFD3_k127_5842189_12 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 398.0
HFD3_k127_5842189_13 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006531 349.0
HFD3_k127_5842189_14 SPFH Band 7 PHB domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006986 346.0
HFD3_k127_5842189_15 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 304.0
HFD3_k127_5842189_16 Bacillithiol biosynthesis BshC K22136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005539 317.0
HFD3_k127_5842189_17 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005615 276.0
HFD3_k127_5842189_18 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003884 276.0
HFD3_k127_5842189_19 PFAM Type II secretion system F domain K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006195 267.0
HFD3_k127_5842189_2 Carboxypeptidase regulatory-like domain - - - 3.687e-206 679.0
HFD3_k127_5842189_20 isomerase activity K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000001016 241.0
HFD3_k127_5842189_21 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000002731 241.0
HFD3_k127_5842189_22 Belongs to the DapA family K01714,K22397 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0019520,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0047440,GO:0071704,GO:0072329,GO:1901575 4.1.2.28,4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000002153 237.0
HFD3_k127_5842189_23 - - - - 0.00000000000000000000000000000000000000000000000000000000000000002263 227.0
HFD3_k127_5842189_24 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000003446 225.0
HFD3_k127_5842189_25 Participates in transcription elongation, termination and antitermination - - - 0.0000000000000000000000000000000000000000000000000000000000005387 226.0
HFD3_k127_5842189_26 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000000007061 201.0
HFD3_k127_5842189_27 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000007714 202.0
HFD3_k127_5842189_28 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000001116 191.0
HFD3_k127_5842189_29 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000001132 183.0
HFD3_k127_5842189_3 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 1.542e-198 628.0
HFD3_k127_5842189_30 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000000396 178.0
HFD3_k127_5842189_31 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000155 183.0
HFD3_k127_5842189_32 Low affinity iron permease - - - 0.0000000000000000000000000000000000000000000005242 173.0
HFD3_k127_5842189_33 Rossmann-like domain - - - 0.00000000000000000000000000000000000000000002074 173.0
HFD3_k127_5842189_34 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000005266 165.0
HFD3_k127_5842189_35 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000004534 167.0
HFD3_k127_5842189_36 BMC - - - 0.0000000000000000000000000000000000002872 146.0
HFD3_k127_5842189_37 - - - - 0.000000000000000000000000000000000001439 141.0
HFD3_k127_5842189_38 ECF sigma factor K03088 - - 0.000000000000000000000000000000000002207 145.0
HFD3_k127_5842189_39 type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000001101 154.0
HFD3_k127_5842189_4 PFAM TonB-dependent Receptor Plug - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009517 625.0
HFD3_k127_5842189_40 - - - - 0.000000000000000000000000000000005402 132.0
HFD3_k127_5842189_41 PFAM Haloacid dehalogenase domain protein hydrolase - - - 0.000000000000000000000000000000009603 136.0
HFD3_k127_5842189_42 amine dehydrogenase activity - - - 0.000000000000000000000000000002434 131.0
HFD3_k127_5842189_43 Carbon dioxide concentrating mechanism carboxysome shell protein - - - 0.00000000000000000000000000002471 119.0
HFD3_k127_5842189_44 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000001503 123.0
HFD3_k127_5842189_45 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000001509 119.0
HFD3_k127_5842189_46 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.0000000000000000000000000464 112.0
HFD3_k127_5842189_47 Biotin-requiring enzyme - - - 0.000000000000000000001289 103.0
HFD3_k127_5842189_48 Belongs to the UPF0237 family K07166 - - 0.0000000000000000005795 92.0
HFD3_k127_5842189_49 WD40 domain protein beta Propeller - - - 0.000000000000001072 92.0
HFD3_k127_5842189_5 UPF0210 protein K09157 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005047 560.0
HFD3_k127_5842189_50 Helix-turn-helix domain K15539 - - 0.0000000000001259 78.0
HFD3_k127_5842189_52 Pilus assembly protein K02662 - - 0.0000005872 61.0
HFD3_k127_5842189_53 Peptidase M16 inactive domain - - - 0.000004737 57.0
HFD3_k127_5842189_54 - - - - 0.0000205 50.0
HFD3_k127_5842189_55 - - - - 0.00005667 50.0
HFD3_k127_5842189_56 Anti-sigma K factor RskA - - - 0.0001334 52.0
HFD3_k127_5842189_6 Esterase of the alpha-beta hydrolase superfamily K07001 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 562.0
HFD3_k127_5842189_7 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006457 533.0
HFD3_k127_5842189_8 AAA ATPase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 524.0
HFD3_k127_5842189_9 COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit K01965 - 6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 502.0
HFD3_k127_5852147_0 serine threonine protein kinase K12132 - 2.7.11.1 1.217e-221 722.0
HFD3_k127_5852147_1 PFAM NAD-dependent epimerase dehydratase - - - 6.482e-219 688.0
HFD3_k127_5852147_10 Lipocalin-like domain K03098 - - 0.0000000000000000000000000000000000000000000000000307 185.0
HFD3_k127_5852147_11 Beta-Ig-H3 fasciclin - - - 0.0000000000000000000000000000000000000000000002294 174.0
HFD3_k127_5852147_12 ketosteroid isomerase - - - 0.0000000000000000000000000000000000000000000003014 170.0
HFD3_k127_5852147_13 - - - - 0.0000000000000000000000000000000000374 143.0
HFD3_k127_5852147_14 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000005834 83.0
HFD3_k127_5852147_15 PFAM pentapeptide repeat protein - - - 0.0000000000000001179 88.0
HFD3_k127_5852147_16 TIGRFAM DNA binding domain protein, excisionase family K22491 - - 0.0000000000000006363 88.0
HFD3_k127_5852147_17 - - - - 0.000000000006284 72.0
HFD3_k127_5852147_18 Phage integrase, N-terminal SAM-like domain - - - 0.0000000001309 65.0
HFD3_k127_5852147_2 Involved in the tonB-independent uptake of proteins K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000079 493.0
HFD3_k127_5852147_20 - - - - 0.0000003101 61.0
HFD3_k127_5852147_21 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000002602 49.0
HFD3_k127_5852147_22 SnoaL-like domain - - - 0.0001209 45.0
HFD3_k127_5852147_23 Domain of unknown function (DUF4440) - - - 0.0005002 48.0
HFD3_k127_5852147_24 - - - - 0.0007442 43.0
HFD3_k127_5852147_3 FG-GAP repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000763 342.0
HFD3_k127_5852147_4 phosphotransferase activity, carboxyl group as acceptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006463 304.0
HFD3_k127_5852147_5 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 304.0
HFD3_k127_5852147_6 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 326.0
HFD3_k127_5852147_7 TIR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000007016 237.0
HFD3_k127_5852147_8 SERine Proteinase INhibitors K13963 - - 0.0000000000000000000000000000000000000000000000000000000000000000002319 241.0
HFD3_k127_5852147_9 Histidine kinase-like ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000005371 218.0
HFD3_k127_5910671_0 Tetratricopeptide repeat - - - 3.68e-221 723.0
HFD3_k127_5910671_1 Bacterial protein of unknown function (DUF885) - - - 2.678e-204 654.0
HFD3_k127_5910671_10 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000000000002325 222.0
HFD3_k127_5910671_11 RNA polymerase, sigma-24 subunit, ECF subfamily K02405 - - 0.00000000000000000000000000000000000000000000000000000000009073 209.0
HFD3_k127_5910671_12 Ferritin-like domain - - - 0.000000000000000000000000000000000000000000000000000000004272 203.0
HFD3_k127_5910671_13 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000005776 200.0
HFD3_k127_5910671_14 von Willebrand factor, type A K07114,K12511 - - 0.00000000000000000000000001189 124.0
HFD3_k127_5910671_15 TIR domain - - - 0.0000000000000000000000025 115.0
HFD3_k127_5910671_2 Aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 512.0
HFD3_k127_5910671_3 amino acid peptide transporter K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 486.0
HFD3_k127_5910671_4 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 467.0
HFD3_k127_5910671_5 cAMP biosynthetic process K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004735 471.0
HFD3_k127_5910671_6 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007404 361.0
HFD3_k127_5910671_7 PFAM Peptidase M1 membrane alanine aminopeptidase K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008155 348.0
HFD3_k127_5910671_8 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000009134 284.0
HFD3_k127_5910671_9 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000318 293.0
HFD3_k127_5947177_0 Cys/Met metabolism PLP-dependent enzyme K01760,K17217 - 4.4.1.1,4.4.1.2,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005579 501.0
HFD3_k127_5947177_1 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 480.0
HFD3_k127_5947177_10 ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009139 314.0
HFD3_k127_5947177_11 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008263 309.0
HFD3_k127_5947177_12 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 302.0
HFD3_k127_5947177_13 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 298.0
HFD3_k127_5947177_14 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007948 274.0
HFD3_k127_5947177_15 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000004113 245.0
HFD3_k127_5947177_16 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000001589 233.0
HFD3_k127_5947177_17 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000001785 229.0
HFD3_k127_5947177_18 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000007821 213.0
HFD3_k127_5947177_19 Domain of unknown function (DUF4162) K01990 - - 0.00000000000000000000000000000000000000000000000000001173 209.0
HFD3_k127_5947177_2 membrane protein, TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 400.0
HFD3_k127_5947177_20 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000006938 177.0
HFD3_k127_5947177_21 Transport permease protein K01992 - - 0.00000000000000000000000000000000000002779 154.0
HFD3_k127_5947177_22 PTS system fructose IIA component K02793,K02794,K02821 - 2.7.1.191,2.7.1.194 0.000000000000000000000000000000005637 132.0
HFD3_k127_5947177_23 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000001497 127.0
HFD3_k127_5947177_24 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000002562 124.0
HFD3_k127_5947177_25 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K09774 - - 0.00000000000000000000004365 116.0
HFD3_k127_5947177_26 PFAM ABC transporter transmembrane region K06147 - - 0.0000000000000000000008993 100.0
HFD3_k127_5947177_27 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00000000000000000001514 105.0
HFD3_k127_5947177_28 NfeD-like C-terminal, partner-binding - - - 0.00000000000000001084 89.0
HFD3_k127_5947177_29 Belongs to the peptidase M16 family - - - 0.00000000000001426 87.0
HFD3_k127_5947177_3 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 389.0
HFD3_k127_5947177_31 - - - - 0.00009953 48.0
HFD3_k127_5947177_32 CAAX protease self-immunity K07052 - - 0.0001088 53.0
HFD3_k127_5947177_4 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 372.0
HFD3_k127_5947177_5 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 374.0
HFD3_k127_5947177_6 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 385.0
HFD3_k127_5947177_7 RNA polymerase sigma-54 factor K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 355.0
HFD3_k127_5947177_8 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 343.0
HFD3_k127_5947177_9 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 318.0
HFD3_k127_6007802_0 MviN-like protein K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 581.0
HFD3_k127_6007802_1 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 460.0
HFD3_k127_6007802_10 - - - - 0.0000000000000000001332 96.0
HFD3_k127_6007802_11 - - - - 0.0000000001058 63.0
HFD3_k127_6007802_13 Aldo/keto reductase family - - - 0.00002358 49.0
HFD3_k127_6007802_2 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 308.0
HFD3_k127_6007802_3 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003733 278.0
HFD3_k127_6007802_4 TIGRFAM Cell shape determining protein MreB Mrl K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004986 263.0
HFD3_k127_6007802_5 Peptidase, M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000005368 229.0
HFD3_k127_6007802_6 Sortase and related acyltransferases K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000000000000003651 218.0
HFD3_k127_6007802_7 SnoaL-like domain K06893 - - 0.0000000000000000000000000000000000000005363 158.0
HFD3_k127_6007802_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000125 136.0
HFD3_k127_6007802_9 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000002095 129.0
HFD3_k127_6100131_0 Aconitase C-terminal domain K01703 - 4.2.1.33,4.2.1.35 3.951e-284 886.0
HFD3_k127_6100131_1 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 357.0
HFD3_k127_6100131_10 Thioredoxin-like - - - 0.00003284 48.0
HFD3_k127_6100131_11 Putative zinc-finger - - - 0.0006586 51.0
HFD3_k127_6100131_12 Bacterial regulatory protein, Fis family K02584 - - 0.0007284 46.0
HFD3_k127_6100131_2 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000000000001523 204.0
HFD3_k127_6100131_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000006538 138.0
HFD3_k127_6100131_4 deoxyhypusine monooxygenase activity K05385 - - 0.0000000000000000000000004408 119.0
HFD3_k127_6100131_5 HEAT repeats - - - 0.00000000000000000000000222 119.0
HFD3_k127_6100131_6 Thioredoxin-like - - - 0.000000000000000000004677 106.0
HFD3_k127_6100131_7 oxidoreductase activity K12511 - - 0.000000000001271 80.0
HFD3_k127_6100131_8 helix_turn_helix, arabinose operon control protein K07506 - - 0.000000000041 67.0
HFD3_k127_6100131_9 Glutathione peroxidase - - - 0.0000007013 59.0
HFD3_k127_6211264_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 7.068e-290 915.0
HFD3_k127_6211264_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 528.0
HFD3_k127_6211264_10 MraW methylase family K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000819 295.0
HFD3_k127_6211264_11 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 299.0
HFD3_k127_6211264_12 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K22024 - 1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 291.0
HFD3_k127_6211264_13 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000202 248.0
HFD3_k127_6211264_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000006884 222.0
HFD3_k127_6211264_15 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000003604 193.0
HFD3_k127_6211264_16 - - - - 0.00000000000000000000000000000000000000000000007894 177.0
HFD3_k127_6211264_17 Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000000000000000000000000000000004141 166.0
HFD3_k127_6211264_18 Domain of unknown function (DUF4440) - - - 0.00000000000000000000000000000000000125 148.0
HFD3_k127_6211264_19 response regulator - - - 0.0000000000000000000000000000000000195 150.0
HFD3_k127_6211264_2 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000585 498.0
HFD3_k127_6211264_20 Xanthine and CO dehydrogenases maturation factor XdhC CoxF K07402 - - 0.00000000000000000000001755 104.0
HFD3_k127_6211264_21 Hfq protein - - - 0.0000000000000000000001932 101.0
HFD3_k127_6211264_22 methyltransferase - - - 0.0000000000000000002248 98.0
HFD3_k127_6211264_23 7TM diverse intracellular signalling - - - 0.0000000000000008844 82.0
HFD3_k127_6211264_24 Cell division protein FtsQ K03589 - - 0.00003067 55.0
HFD3_k127_6211264_25 rhs family - - - 0.0001157 47.0
HFD3_k127_6211264_26 Type II secretion system (T2SS), protein G K02456 - - 0.0007129 51.0
HFD3_k127_6211264_27 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic - - - 0.0009642 46.0
HFD3_k127_6211264_3 Vault protein inter-alpha-trypsin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004669 445.0
HFD3_k127_6211264_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 422.0
HFD3_k127_6211264_5 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 408.0
HFD3_k127_6211264_6 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 394.0
HFD3_k127_6211264_7 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 354.0
HFD3_k127_6211264_8 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 323.0
HFD3_k127_6211264_9 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 321.0
HFD3_k127_6249666_0 Alpha-2-Macroglobulin K06894 - - 1.078e-304 991.0
HFD3_k127_6249666_1 PFAM Prolyl oligopeptidase family - - - 1.135e-275 861.0
HFD3_k127_6249666_10 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000002229 210.0
HFD3_k127_6249666_11 Protein of unknown function (DUF1175) K09934 - - 0.000000000000000000000000000000000000000000000000001011 193.0
HFD3_k127_6249666_12 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000007012 169.0
HFD3_k127_6249666_14 Amidohydrolase family - - - 0.0000000000000000000000000000000000011 145.0
HFD3_k127_6249666_15 bacterial-type flagellum-dependent cell motility - - - 0.00000000000000000000000000001309 124.0
HFD3_k127_6249666_17 Penicillin binding protein transpeptidase domain - - - 0.00000000000000000000000002061 127.0
HFD3_k127_6249666_18 extracellular polysaccharide biosynthetic process K13582 - - 0.00000000000000000000009266 110.0
HFD3_k127_6249666_19 Cytochrome c biogenesis protein transmembrane region K04084 - 1.8.1.8 0.00000000000000000005722 96.0
HFD3_k127_6249666_2 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 561.0
HFD3_k127_6249666_20 - K05826 - - 0.0000000003672 62.0
HFD3_k127_6249666_21 domain protein K14475 - - 0.0000001709 61.0
HFD3_k127_6249666_22 von Willebrand factor, type A - - - 0.0000002148 63.0
HFD3_k127_6249666_3 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007813 464.0
HFD3_k127_6249666_4 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 418.0
HFD3_k127_6249666_5 double-stranded DNA 3'-5' exodeoxyribonuclease activity K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000849 299.0
HFD3_k127_6249666_6 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000001946 252.0
HFD3_k127_6249666_7 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001193 258.0
HFD3_k127_6249666_8 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000001985 238.0
HFD3_k127_6249666_9 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000000000000000000000003484 230.0
HFD3_k127_6266120_0 Two component, sigma54 specific, transcriptional regulator, Fis family K02667,K07713,K07714,K19641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 398.0
HFD3_k127_6266120_1 histidine kinase, HAMP - - - 0.0000000000000000000000000000000000000000000000000001959 198.0
HFD3_k127_6277455_0 Conserved protein K09704 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 574.0
HFD3_k127_6277455_1 ABC transporter K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009322 355.0
HFD3_k127_6277455_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 310.0
HFD3_k127_6277455_3 cellulose binding - - - 0.00000000000000000000000000000000005174 134.0
HFD3_k127_6281054_0 Catalyzes the synthesis of activated sulfate K00958 - 2.7.7.4 3.519e-251 787.0
HFD3_k127_6281054_1 von Willebrand factor, type A K07114 - - 1.704e-214 685.0
HFD3_k127_6281054_11 - - - - 0.000000000000000000000000000000000000000000000000000000005376 202.0
HFD3_k127_6281054_12 WD40-like Beta Propeller Repeat K03641 - - 0.000000000000000000000000000000000000000000000000000000007391 220.0
HFD3_k127_6281054_13 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000001687 202.0
HFD3_k127_6281054_14 RTX toxins and related Ca2 binding proteins - - - 0.00000000000000000000000000000000000000000000001715 197.0
HFD3_k127_6281054_15 YndJ-like protein - - - 0.00000000000000000000000000000000000000004389 166.0
HFD3_k127_6281054_17 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.00000000000000000000000000000000000000211 148.0
HFD3_k127_6281054_18 BtpA family K06971 - - 0.0000000000000000000000000000000000519 138.0
HFD3_k127_6281054_19 DUF based on E. rectale Gene description (DUF3880) K06320 - - 0.000000000000000000000000000000004202 142.0
HFD3_k127_6281054_2 Protein kinase domain K12132 - 2.7.11.1 1.357e-211 691.0
HFD3_k127_6281054_21 RTX toxins and related Ca2 binding proteins - - - 0.000000000000000000000000001485 132.0
HFD3_k127_6281054_22 - - - - 0.0000000000000000000000001328 116.0
HFD3_k127_6281054_23 Protein of unknown function (DUF3455) - - - 0.00000000000000000000001311 110.0
HFD3_k127_6281054_24 Methyltransferase domain - - - 0.0000000000000000000004519 112.0
HFD3_k127_6281054_25 MerR HTH family regulatory protein - - - 0.0000000000000003432 87.0
HFD3_k127_6281054_26 Domain of unknown function (DUF4190) - - - 0.00000000000006001 82.0
HFD3_k127_6281054_27 Cellulase (glycosyl hydrolase family 5) K01179 - 3.2.1.4 0.0000000000001274 84.0
HFD3_k127_6281054_28 Serine aminopeptidase, S33 - - - 0.0000003883 62.0
HFD3_k127_6281054_29 - - - - 0.000341 52.0
HFD3_k127_6281054_3 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004629 489.0
HFD3_k127_6281054_4 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 434.0
HFD3_k127_6281054_5 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 410.0
HFD3_k127_6281054_6 Belongs to the heat shock protein 70 family K04046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003497 396.0
HFD3_k127_6281054_7 methyltransferase activity K21310 - 2.1.1.334 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 331.0
HFD3_k127_6281054_8 von Willebrand factor type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004758 299.0
HFD3_k127_6281054_9 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005822 261.0
HFD3_k127_6341746_0 CHAT domain - - - 5.107e-303 966.0
HFD3_k127_6341746_1 Radical SAM - - - 8.852e-219 696.0
HFD3_k127_6341746_10 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K08641,K11206 - 3.4.13.22 0.00000000000000000000005643 100.0
HFD3_k127_6341746_11 GAF domain K02482 - 2.7.13.3 0.0000143 51.0
HFD3_k127_6341746_12 DNA integration K14059 - - 0.0001746 44.0
HFD3_k127_6341746_2 Sodium Bile acid symporter family K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 546.0
HFD3_k127_6341746_3 Methylase involved in ubiquinone menaquinone K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009637 387.0
HFD3_k127_6341746_4 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000724 306.0
HFD3_k127_6341746_5 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 299.0
HFD3_k127_6341746_6 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 289.0
HFD3_k127_6341746_7 PFAM Organic solvent tolerance protein K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008898 280.0
HFD3_k127_6341746_8 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000008153 256.0
HFD3_k127_6341746_9 Domain of unknown function (DUF4157) K01227,K01448,K03791,K13277,K17733 - 3.2.1.96,3.5.1.28 0.0000000000000000000000000000000000000000000000000000001052 208.0
HFD3_k127_6380722_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 6.972e-311 965.0
HFD3_k127_6380722_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000544 449.0
HFD3_k127_6380722_10 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000000000006717 155.0
HFD3_k127_6380722_11 AI-2E family transporter - - - 0.000000000000000000000000000000000003299 153.0
HFD3_k127_6380722_12 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000002282 88.0
HFD3_k127_6380722_2 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 441.0
HFD3_k127_6380722_3 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 323.0
HFD3_k127_6380722_4 PFAM peptidase M19 renal dipeptidase K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 322.0
HFD3_k127_6380722_5 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 306.0
HFD3_k127_6380722_6 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001133 272.0
HFD3_k127_6380722_7 Lumazine binding domain K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000001627 214.0
HFD3_k127_6380722_8 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000000000000000000000000000000000000001107 196.0
HFD3_k127_6380722_9 Y_Y_Y domain - - - 0.0000000000000000000000000000000000000004191 173.0
HFD3_k127_6390630_0 Carboxypeptidase regulatory-like domain - - - 5.851e-224 739.0
HFD3_k127_6390630_1 4Fe-4S binding domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 338.0
HFD3_k127_6390630_2 PFAM TonB-dependent Receptor Plug - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008165 332.0
HFD3_k127_6390630_3 Amidohydrolase family K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000004444 259.0
HFD3_k127_6390630_4 Glycosyl hydrolase-like 10 - - - 0.0000000000000000000000000000000000000000003077 173.0
HFD3_k127_6390630_5 tail collar domain protein - - - 0.00000000000000000000000000000000000000001927 163.0
HFD3_k127_6390630_6 - - - - 0.0000000006492 69.0
HFD3_k127_640820_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 7.441e-285 885.0
HFD3_k127_640820_1 4Fe-4S single cluster domain of Ferredoxin I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 361.0
HFD3_k127_640820_2 Uncharacterised nucleotidyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000159 232.0
HFD3_k127_640820_3 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000001451 165.0
HFD3_k127_640820_4 Radical SAM superfamily K22226 - - 0.00000000000000000000000000000000000152 151.0
HFD3_k127_640820_5 PFAM Response regulator receiver domain - - - 0.0000000000000000002199 92.0
HFD3_k127_640820_6 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.0000000003132 71.0
HFD3_k127_6438274_0 Ketoacyl-synthetase C-terminal extension - - - 0.0 1446.0
HFD3_k127_6438274_1 Amino acid adenylation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 432.0
HFD3_k127_6438274_2 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.00000000000000000000000000000000000000000000000000000000000000000006775 235.0
HFD3_k127_6468253_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 554.0
HFD3_k127_6468253_1 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004095 456.0
HFD3_k127_6468253_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 432.0
HFD3_k127_6468253_3 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006688 366.0
HFD3_k127_6468253_4 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000008695 190.0
HFD3_k127_6468253_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000554 166.0
HFD3_k127_6468253_6 - - - - 0.0000000001465 68.0
HFD3_k127_6468253_7 Domain of unknown function (DUF4190) - - - 0.0000001956 59.0
HFD3_k127_6468253_8 - - - - 0.000001472 59.0
HFD3_k127_6493928_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 482.0
HFD3_k127_6493928_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000001428 189.0
HFD3_k127_6493928_2 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000007997 188.0
HFD3_k127_6493928_3 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000113 177.0
HFD3_k127_6493928_4 TPR repeat - - - 0.00000000000000000000000008402 114.0
HFD3_k127_6493928_5 - - - - 0.000000006915 62.0
HFD3_k127_6493928_6 Putative zinc-finger - - - 0.00005738 49.0
HFD3_k127_650131_0 transport - - - 0.0 1161.0
HFD3_k127_650131_1 ABC transporter transmembrane region K11085 - - 3.139e-236 744.0
HFD3_k127_650131_10 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006836 312.0
HFD3_k127_650131_11 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001756 288.0
HFD3_k127_650131_12 PFAM KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.000000000000000000000000000000000000000000000000000000000000000000000000002638 259.0
HFD3_k127_650131_13 tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000001812 207.0
HFD3_k127_650131_14 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000000000000000000000000000003374 165.0
HFD3_k127_650131_15 Cupin 2, conserved barrel domain protein - - - 0.000000000000000008642 88.0
HFD3_k127_650131_16 Protein conserved in bacteria - - - 0.000000002103 70.0
HFD3_k127_650131_2 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005378 587.0
HFD3_k127_650131_3 Periplasmic binding proteins and sugar binding domain of LacI family K10439,K10552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 460.0
HFD3_k127_650131_4 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 493.0
HFD3_k127_650131_5 Branched-chain amino acid transport system / permease component K10440,K10553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 436.0
HFD3_k127_650131_6 ROK family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 422.0
HFD3_k127_650131_7 enzyme involved in inositol metabolism K03337 - 5.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 354.0
HFD3_k127_650131_8 PFAM Short-chain dehydrogenase reductase SDR K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 340.0
HFD3_k127_650131_9 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 317.0
HFD3_k127_6574505_0 Alpha-L-arabinofuranosidase K01209 - 3.2.1.55 3.156e-260 817.0
HFD3_k127_6574505_1 protein conserved in bacteria K09955 - - 3.182e-259 821.0
HFD3_k127_6574505_10 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007344 374.0
HFD3_k127_6574505_11 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003973 280.0
HFD3_k127_6574505_12 PFAM transglutaminase domain protein - - - 0.000000000000000000000000000000000002042 147.0
HFD3_k127_6574505_2 carboxylic acid catabolic process K01187 - 3.2.1.20 4.091e-256 806.0
HFD3_k127_6574505_3 alpha-L-arabinofuranosidase K01209 - 3.2.1.55 2.266e-244 774.0
HFD3_k127_6574505_4 Belongs to the xylose isomerase family K01805 - 5.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 611.0
HFD3_k127_6574505_5 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 598.0
HFD3_k127_6574505_6 Cellulase (glycosyl hydrolase family 5) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009313 523.0
HFD3_k127_6574505_7 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 436.0
HFD3_k127_6574505_8 CHAT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 442.0
HFD3_k127_6574505_9 ABC-type sugar transport system periplasmic component K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 409.0
HFD3_k127_6597505_0 alpha-L-arabinofuranosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009956 478.0
HFD3_k127_6597505_1 SCO1/SenC K07152,K08976 - - 0.0000004544 55.0
HFD3_k127_6623657_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 490.0
HFD3_k127_6623657_1 Mur ligase middle domain K02558 - 6.3.2.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 475.0
HFD3_k127_6623657_10 Hexapeptide repeat of succinyl-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007247 247.0
HFD3_k127_6623657_11 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000002855 224.0
HFD3_k127_6623657_12 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000005648 214.0
HFD3_k127_6623657_13 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - - 0.00000000000000000000000000000000000000000000000000000001325 204.0
HFD3_k127_6623657_14 SCO1/SenC - - - 0.0000000000000000000000000000000000000000000000000000001154 203.0
HFD3_k127_6623657_15 - - - - 0.0000000000000000000000000000000000000000000000000009322 197.0
HFD3_k127_6623657_16 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000001824 184.0
HFD3_k127_6623657_17 Domain of unknown function (DUF4114) - - - 0.0000000000000000000000000000000000000000000008324 192.0
HFD3_k127_6623657_18 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000002455 169.0
HFD3_k127_6623657_19 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000004365 166.0
HFD3_k127_6623657_2 Multicopper oxidase K14588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 449.0
HFD3_k127_6623657_20 PFAM von Willebrand factor type A - - - 0.000000000000000000000000000000009552 141.0
HFD3_k127_6623657_21 Parallel beta-helix repeats - - - 0.00000000000000000000000000002598 128.0
HFD3_k127_6623657_22 - - - - 0.0000000000000000000000000001622 132.0
HFD3_k127_6623657_23 Protein of unknown function (DUF1232) - - - 0.00000000000000000000000005274 114.0
HFD3_k127_6623657_24 Protein of unknown function DUF115 - - - 0.00000000000000000000001504 111.0
HFD3_k127_6623657_26 AraC-like ligand binding domain - - - 0.000000000000005063 81.0
HFD3_k127_6623657_27 Sensory domain in DIguanylate Cyclases and Two-component system - - - 0.00000000000003331 80.0
HFD3_k127_6623657_28 von Willebrand factor, type A - - - 0.00000006057 65.0
HFD3_k127_6623657_3 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005957 437.0
HFD3_k127_6623657_4 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006193 444.0
HFD3_k127_6623657_5 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 431.0
HFD3_k127_6623657_6 Phytanoyl-CoA dioxygenase (PhyH) K00477 - 1.14.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 359.0
HFD3_k127_6623657_7 Phosphate acetyl/butaryl transferase K00625,K13788 GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 341.0
HFD3_k127_6623657_8 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 307.0
HFD3_k127_6623657_9 Multicopper oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009782 262.0
HFD3_k127_6648111_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 5.054e-205 645.0
HFD3_k127_6648111_1 phosphoesterase, PA-phosphatase related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749 526.0
HFD3_k127_6648111_10 Cytochrome b(C-terminal)/b6/petD K00412 - - 0.0000000000000000000000000000000000000000003086 175.0
HFD3_k127_6648111_11 - - - - 0.00000000000000000000000000000000000000004149 167.0
HFD3_k127_6648111_12 peptidyl-prolyl cis-trans isomerase K03772,K03773 - 5.2.1.8 0.000000000000000000000000000000001144 136.0
HFD3_k127_6648111_13 Sigma-70, region 4 - - - 0.000000000000000000000000000001499 128.0
HFD3_k127_6648111_14 Rieske [2Fe-2S] domain K03886 - - 0.00000000000000000000000006705 113.0
HFD3_k127_6648111_15 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000001027 103.0
HFD3_k127_6648111_16 Pilus assembly protein PilX K02673 - - 0.0000000000002156 83.0
HFD3_k127_6648111_17 - - - - 0.000003531 54.0
HFD3_k127_6648111_18 ATP-independent chaperone mediated protein folding K06006 - - 0.00002261 55.0
HFD3_k127_6648111_19 Cytochrome c K00406,K08906 - - 0.00005735 51.0
HFD3_k127_6648111_2 AAA ATPase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000674 454.0
HFD3_k127_6648111_20 Beta-galactosidase K12308 - 3.2.1.23 0.00007805 56.0
HFD3_k127_6648111_21 pilus assembly protein PilW K02672 - - 0.0001255 52.0
HFD3_k127_6648111_3 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 417.0
HFD3_k127_6648111_4 TAP-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 361.0
HFD3_k127_6648111_5 Arginase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008566 292.0
HFD3_k127_6648111_6 Chlorite dismutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008517 281.0
HFD3_k127_6648111_7 Serine threonine protein kinase K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000136 239.0
HFD3_k127_6648111_8 Membrane - - - 0.0000000000000000000000000000000000000000000000000154 202.0
HFD3_k127_6648111_9 Peptidase, M16 - - - 0.000000000000000000000000000000000000000000000904 175.0
HFD3_k127_6783175_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 2.612e-309 954.0
HFD3_k127_6783175_1 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 2.022e-300 944.0
HFD3_k127_6783175_10 Peptidase inhibitor I9 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 396.0
HFD3_k127_6783175_11 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 364.0
HFD3_k127_6783175_12 PFAM ABC-1 domain protein K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 349.0
HFD3_k127_6783175_13 PFAM transposase IS116 IS110 IS902 family K07486 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 331.0
HFD3_k127_6783175_14 SMART PBS lyase HEAT domain protein repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005184 304.0
HFD3_k127_6783175_15 Protein of unknown function (DUF1702) K21161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002934 282.0
HFD3_k127_6783175_16 Major Facilitator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002501 285.0
HFD3_k127_6783175_17 AMP-binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000005013 246.0
HFD3_k127_6783175_18 Bacterial protein of unknown function (DUF899) - - - 0.000000000000000000000000000000000000000000000000000000000000000003297 231.0
HFD3_k127_6783175_19 - - - - 0.00000000000000000000000000000000000000000000000000000000000000023 228.0
HFD3_k127_6783175_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 3.768e-244 764.0
HFD3_k127_6783175_20 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000003897 224.0
HFD3_k127_6783175_21 BON domain K04065 - - 0.000000000000000000000000000000000000000000000000000000000000864 218.0
HFD3_k127_6783175_22 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000000000000000000000000000000000002651 211.0
HFD3_k127_6783175_23 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000001355 209.0
HFD3_k127_6783175_24 - - - - 0.0000000000000000000000000000000000000000000000000000000007075 210.0
HFD3_k127_6783175_25 COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase - - - 0.000000000000000000000000000000000000000000000000000000002 210.0
HFD3_k127_6783175_26 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000001489 204.0
HFD3_k127_6783175_27 bacterial OsmY and nodulation domain - - - 0.00000000000000000000000000000000000000000000000000006501 196.0
HFD3_k127_6783175_28 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000007104 199.0
HFD3_k127_6783175_29 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000002843 141.0
HFD3_k127_6783175_3 Elongator protein 3, MiaB family, Radical SAM K18537,K21224 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005801 617.0
HFD3_k127_6783175_30 Universal stress protein family - - - 0.000000000000000000000000000000001093 137.0
HFD3_k127_6783175_32 maltose O-acetyltransferase activity - - - 0.00000000000000000000000000000002498 138.0
HFD3_k127_6783175_33 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000001179 130.0
HFD3_k127_6783175_34 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.00000000000000000000000000201 113.0
HFD3_k127_6783175_35 thioesterase involved in non-ribosomal peptide biosynthesis - - - 0.00000000000000000000000003438 117.0
HFD3_k127_6783175_36 Belongs to the heme-copper respiratory oxidase family - - - 0.000000000000000000000003046 108.0
HFD3_k127_6783175_37 Transmembrane secretion effector - - - 0.000000000000000000002997 107.0
HFD3_k127_6783175_38 - - - - 0.000000000000000226 87.0
HFD3_k127_6783175_39 Phosphopantetheine attachment site K02078 - - 0.00000000000001526 77.0
HFD3_k127_6783175_4 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 597.0
HFD3_k127_6783175_40 Cupin 2, conserved barrel domain protein - - - 0.00000000000007724 79.0
HFD3_k127_6783175_41 Domain of unknown function (DUF4136) - - - 0.00000000000131 75.0
HFD3_k127_6783175_42 Domain of unknown function (DUF4404) - - - 0.000000001154 62.0
HFD3_k127_6783175_43 - - - - 0.00000002555 59.0
HFD3_k127_6783175_44 Activator of Hsp90 ATPase homolog 1-like - - - 0.00001692 55.0
HFD3_k127_6783175_45 SnoaL-like domain - - - 0.00007258 52.0
HFD3_k127_6783175_46 Aspartyl/Asparaginyl beta-hydroxylase - - - 0.0005438 51.0
HFD3_k127_6783175_47 SnoaL-like domain - - - 0.0007788 49.0
HFD3_k127_6783175_5 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007249 538.0
HFD3_k127_6783175_6 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00162,K11381 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 501.0
HFD3_k127_6783175_7 S-acyltransferase activity K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 445.0
HFD3_k127_6783175_8 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00161,K00162,K11381,K21416 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 437.0
HFD3_k127_6783175_9 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004591 431.0
HFD3_k127_6805564_0 Dienelactone hydrolase family - - - 0.0 1161.0
HFD3_k127_6805564_1 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 5.223e-228 714.0
HFD3_k127_6805564_10 DNA polymerase beta domain protein region K07075 - - 0.0000002535 56.0
HFD3_k127_6805564_11 Domain of unknown function (DUF1736) - - - 0.0000003009 57.0
HFD3_k127_6805564_2 Phosphate acyltransferases K00655,K01897 - 2.3.1.51,6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006331 543.0
HFD3_k127_6805564_3 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000007307 198.0
HFD3_k127_6805564_4 Damage-inducible protein DinB - - - 0.000000000000000000000000000000000000000000000000000776 188.0
HFD3_k127_6805564_5 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000000000002153 158.0
HFD3_k127_6805564_6 Protein of unknown function (DUF2834) - - - 0.000000000000000000000000000000009565 130.0
HFD3_k127_6805564_7 hyperosmotic response - - - 0.00000000000000000000000000000001195 132.0
HFD3_k127_6805564_8 Universal stress protein family - - - 0.0000000000000000000000007601 109.0
HFD3_k127_6805564_9 Belongs to the GMC oxidoreductase family K00108 - 1.1.99.1 0.000000000000009124 75.0
HFD3_k127_6855870_0 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006254 250.0
HFD3_k127_6855870_1 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000005862 126.0
HFD3_k127_6859169_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1225.0
HFD3_k127_6859169_1 TonB dependent receptor K16090 - - 2.137e-224 719.0
HFD3_k127_6859169_2 PepSY-associated TM region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 393.0
HFD3_k127_6859169_3 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 326.0
HFD3_k127_6859169_4 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00000000000000491 79.0
HFD3_k127_6859169_5 TonB-dependent receptor - - - 0.00000000000001848 79.0
HFD3_k127_6859169_6 - - - - 0.000001612 50.0
HFD3_k127_68784_0 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009067 324.0
HFD3_k127_68784_1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 323.0
HFD3_k127_68784_2 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009141 332.0
HFD3_k127_68784_3 Serine Threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 318.0
HFD3_k127_68784_4 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000002722 222.0
HFD3_k127_68784_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000001538 233.0
HFD3_k127_68784_6 Phage integrase, N-terminal SAM-like domain K14059 - - 0.00000000000000000000000000000001405 132.0
HFD3_k127_6923386_0 beta-galactosidase activity - - - 4.291e-211 662.0
HFD3_k127_6923386_2 - - - - 0.0000000000000000000000000000000000000000000003654 171.0
HFD3_k127_6923386_3 - - - - 0.00000000000000000000000000002628 117.0
HFD3_k127_6923386_4 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000000001656 98.0
HFD3_k127_6923386_5 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000004781 82.0
HFD3_k127_6993734_0 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 419.0
HFD3_k127_6993734_1 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006326 302.0
HFD3_k127_6993734_2 COG1230 Co Zn Cd efflux system component K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009109 265.0
HFD3_k127_6993734_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000292 193.0
HFD3_k127_6993734_4 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000005448 174.0
HFD3_k127_6993734_5 HD domain K07023 - - 0.00000000000000000000000000000000001447 143.0
HFD3_k127_6993734_6 zinc-ribbon domain - - - 0.0000000000000002251 88.0
HFD3_k127_7022810_0 Alpha-L-arabinofuranosidase C-terminus K01209 - 3.2.1.55 1.497e-214 679.0
HFD3_k127_7022810_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 425.0
HFD3_k127_7022810_2 glycosyl transferase family 2 K20444 - - 0.000000000000000003944 99.0
HFD3_k127_7022810_3 TIGRFAM galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.0000000000003074 74.0
HFD3_k127_7023366_0 WD domain, G-beta repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 580.0
HFD3_k127_7023366_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 321.0
HFD3_k127_7023366_2 protein homooligomerization - - - 0.000000000000000000000000000000000000000000000000000000000000002531 239.0
HFD3_k127_7023366_3 protein serine/threonine phosphatase activity - - - 0.00000000000000004665 87.0
HFD3_k127_7024988_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 404.0
HFD3_k127_7024988_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009201 293.0
HFD3_k127_7024988_2 - - - - 0.000000000000000000000000000000000000000000000000000004565 199.0
HFD3_k127_7024988_3 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000009389 165.0
HFD3_k127_7024988_4 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000001831 138.0
HFD3_k127_7024988_5 cheY-homologous receiver domain - - - 0.000000000000000000000000005856 114.0
HFD3_k127_7024988_6 Pfam:N_methyl_2 - - - 0.00000000000000001674 92.0
HFD3_k127_7024988_7 Methylase involved in ubiquinone menaquinone biosynthesis K03183 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.163,2.1.1.201 0.0000000000004513 79.0
HFD3_k127_7024988_8 PFAM ATP-binding region, ATPase domain protein - - - 0.0003189 51.0
HFD3_k127_7048560_0 TonB-dependent receptor - - - 0.0 1065.0
HFD3_k127_7048560_1 alpha-L-rhamnosidase - - - 1.02e-286 908.0
HFD3_k127_7048560_10 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000004588 218.0
HFD3_k127_7048560_2 Belongs to the binding-protein-dependent transport system permease family K10559,K10561 - - 2.472e-275 865.0
HFD3_k127_7048560_3 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10562 - 3.6.3.17 5.285e-207 657.0
HFD3_k127_7048560_4 Alpha-L-arabinofuranosidase C-terminus K01209 - 3.2.1.55 5.311e-199 634.0
HFD3_k127_7048560_5 Oligogalacturonate lyase K01730 - 4.2.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 488.0
HFD3_k127_7048560_6 carbohydrate kinase FGGY K00848 - 2.7.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 422.0
HFD3_k127_7048560_7 sugar isomerase K01820 - 5.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007211 350.0
HFD3_k127_7048560_8 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 341.0
HFD3_k127_7048560_9 Belongs to the binding-protein-dependent transport system permease family K10560 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 334.0
HFD3_k127_7085378_0 Sulfatase K01130 - 3.1.6.1 0.0 1372.0
HFD3_k127_7085378_1 Amidohydrolase family K06015 - 3.5.1.81 2.911e-214 684.0
HFD3_k127_7085378_10 Protein of unknown function (DUF1622) - - - 0.000000000000000000000000162 112.0
HFD3_k127_7085378_11 Domain of unknown function (DUF202) K00389 - - 0.000000000000000000002009 100.0
HFD3_k127_7085378_2 Iron-sulfur cluster-binding domain K06871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 614.0
HFD3_k127_7085378_3 cAMP biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001016 296.0
HFD3_k127_7085378_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006 269.0
HFD3_k127_7085378_5 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000000000001594 204.0
HFD3_k127_7085378_6 long-chain fatty acid transport protein - - - 0.00000000000000000000000000000000000000000002593 174.0
HFD3_k127_7085378_7 Peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000002395 157.0
HFD3_k127_7085378_9 - - - - 0.000000000000000000000000000000000008137 142.0
HFD3_k127_7094585_0 A-macroglobulin complement component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008716 553.0
HFD3_k127_7094585_1 Protein of unknown function (DUF2891) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 476.0
HFD3_k127_7094585_2 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000001827 172.0
HFD3_k127_7094585_3 signal peptide processing K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000001212 170.0
HFD3_k127_7146948_0 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008691 570.0
HFD3_k127_7146948_1 NeuB family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 397.0
HFD3_k127_7146948_10 WbqC-like protein family - - - 0.0000000000000000000000000000000000000000000001812 177.0
HFD3_k127_7146948_11 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.00000000000000000005305 100.0
HFD3_k127_7146948_2 UDP-N-acetylglucosamine 2-epimerase K08068,K18429 - 3.2.1.183,3.2.1.184 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000723 379.0
HFD3_k127_7146948_3 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000562 322.0
HFD3_k127_7146948_4 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 313.0
HFD3_k127_7146948_5 Cytidylyltransferase K00983 - 2.7.7.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000101 278.0
HFD3_k127_7146948_6 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002182 252.0
HFD3_k127_7146948_7 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000006715 226.0
HFD3_k127_7146948_8 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000003583 206.0
HFD3_k127_7146948_9 TIGRFAM Sialic acid O-acyltransferase, NeuD - - - 0.000000000000000000000000000000000000000000000000001559 189.0
HFD3_k127_715481_0 NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 546.0
HFD3_k127_715481_1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008128 508.0
HFD3_k127_715481_10 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000001284 174.0
HFD3_k127_715481_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000004947 165.0
HFD3_k127_715481_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000001045 160.0
HFD3_k127_715481_13 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000003868 133.0
HFD3_k127_715481_14 Belongs to the phosphoglycerate mutase family K15634 - 5.4.2.12 0.000000000000000000000000000007463 126.0
HFD3_k127_715481_15 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000001312 121.0
HFD3_k127_715481_16 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K00340 - 1.6.5.3 0.0000000000000000000000000001217 120.0
HFD3_k127_715481_17 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000624 102.0
HFD3_k127_715481_18 transposition, DNA-mediated - - - 0.0000000000005001 74.0
HFD3_k127_715481_19 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00002515 51.0
HFD3_k127_715481_2 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007818 500.0
HFD3_k127_715481_3 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005573 484.0
HFD3_k127_715481_4 Belongs to the N(4) N(6)-methyltransferase family K00571 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007135 439.0
HFD3_k127_715481_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007649 329.0
HFD3_k127_715481_6 Protein of unknown function (DUF1385) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004535 258.0
HFD3_k127_715481_7 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000003774 243.0
HFD3_k127_715481_9 DNA-templated transcription, initiation - - - 0.00000000000000000000000000000000000000000000000000004855 204.0
HFD3_k127_7160751_0 Belongs to the glycosyl hydrolase 43 family - - - 3.312e-217 685.0
HFD3_k127_7160751_1 PFAM Major Facilitator Superfamily K08191 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 574.0
HFD3_k127_7160751_2 Glycosyl Hydrolase Family 88 K15532 - 3.2.1.172 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 520.0
HFD3_k127_7160751_3 FCD K05799 - - 0.00000000000000000000000000000000000000000000000000000000000000001131 233.0
HFD3_k127_7160751_4 polygalacturonase activity K01184 - 3.2.1.15 0.0006317 43.0
HFD3_k127_722859_0 PFAM asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 599.0
HFD3_k127_722859_1 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 527.0
HFD3_k127_722859_2 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 412.0
HFD3_k127_722859_3 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007843 383.0
HFD3_k127_722859_4 Glycosyl transferase 4-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003664 272.0
HFD3_k127_722859_5 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000002004 206.0
HFD3_k127_722859_6 O-Antigen ligase K02847 - - 0.000000000000000000000000000000000000000000003625 182.0
HFD3_k127_722859_7 Methyltransferase domain - - - 0.000000000000000000000000005559 122.0
HFD3_k127_722859_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000001211 56.0
HFD3_k127_722859_9 Cytochrome c554 and c-prime - - - 0.0005851 52.0
HFD3_k127_7351145_0 TIGRFAM amino acid adenylation domain - - - 0.0 1521.0
HFD3_k127_7351145_1 Non-ribosomal peptide synthetase modules and related - - - 0.0 1371.0
HFD3_k127_7351145_2 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007867 440.0
HFD3_k127_7351145_3 Putative methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002354 274.0
HFD3_k127_7351145_4 PFAM AMP-dependent synthetase ligase - - - 0.00000000000000000000000000001785 121.0
HFD3_k127_7351145_5 Amino acid adenylation enzyme thioester reductase family protein - - - 0.0000168 47.0
HFD3_k127_7352166_0 Heat shock 70 kDa protein K04043 - - 1.96e-233 736.0
HFD3_k127_7352166_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 417.0
HFD3_k127_7352166_10 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000007586 224.0
HFD3_k127_7352166_11 nucleotide metabolic process - - - 0.000000000000000000000000000000000000000000000000000002535 200.0
HFD3_k127_7352166_12 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000003893 178.0
HFD3_k127_7352166_13 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.00000000000000000000000000006261 129.0
HFD3_k127_7352166_14 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000004752 73.0
HFD3_k127_7352166_15 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.000004433 51.0
HFD3_k127_7352166_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008653 422.0
HFD3_k127_7352166_3 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009976 308.0
HFD3_k127_7352166_5 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001221 261.0
HFD3_k127_7352166_6 HrcA protein C terminal domain K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002487 263.0
HFD3_k127_7352166_7 Radical SAM superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004749 260.0
HFD3_k127_7352166_8 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000006838 265.0
HFD3_k127_7352166_9 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000000000000000000000000000000314 238.0
HFD3_k127_7366955_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 462.0
HFD3_k127_7366955_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 345.0
HFD3_k127_7366955_10 Lytic transglycosylase catalytic K08309 - - 0.00000000000000000000000000000000002089 156.0
HFD3_k127_7366955_11 tRNA threonylcarbamoyladenosine modification K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 - 0.000000000000000000006794 100.0
HFD3_k127_7366955_12 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000006295 59.0
HFD3_k127_7366955_13 12 heme-binding sites - - - 0.000007924 51.0
HFD3_k127_7366955_2 extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008934 297.0
HFD3_k127_7366955_3 Copper binding periplasmic protein CusF K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008559 282.0
HFD3_k127_7366955_4 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000243 265.0
HFD3_k127_7366955_5 L-threonylcarbamoyladenylate synthase K07566 GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000004774 234.0
HFD3_k127_7366955_6 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000004209 229.0
HFD3_k127_7366955_7 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000006948 175.0
HFD3_k127_7366955_8 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000009447 173.0
HFD3_k127_7366955_9 tRNA threonylcarbamoyladenosine modification K06925,K07102 - 2.7.1.221 0.00000000000000000000000000000000000006251 149.0
HFD3_k127_7384523_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009046 492.0
HFD3_k127_7384523_1 PQQ-like domain - - - 0.0000000000000000000000000000000002674 134.0
HFD3_k127_7384924_0 Fibronectin type III-like domain K05349 - 3.2.1.21 0.0 1068.0
HFD3_k127_7384924_1 Ferredoxin - - - 0.0000000000000000000001428 98.0
HFD3_k127_7406591_0 Acetyl-coenzyme A synthetase N-terminus K01908 - 6.2.1.17 5.202e-304 942.0
HFD3_k127_7406591_1 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 514.0
HFD3_k127_7406591_10 Membrane - - - 0.000000000000000000000002226 109.0
HFD3_k127_7406591_12 peroxiredoxin activity K03564 - 1.11.1.15 0.00000000000000000001603 94.0
HFD3_k127_7406591_13 desaturase K00507 - 1.14.19.1 0.00000000002331 74.0
HFD3_k127_7406591_14 Beta-lactamase - - - 0.00000000002754 69.0
HFD3_k127_7406591_15 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000005586 67.0
HFD3_k127_7406591_16 - - - - 0.0000004322 59.0
HFD3_k127_7406591_17 May be involved in the stabilization of the cell envelope or may interact with the sensor protein CseC to modulate its activity, in response to cell envelope stress - - - 0.0002238 52.0
HFD3_k127_7406591_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 413.0
HFD3_k127_7406591_3 PFAM peptidase M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 361.0
HFD3_k127_7406591_4 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009769 286.0
HFD3_k127_7406591_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000006708 215.0
HFD3_k127_7406591_6 YjbR - - - 0.000000000000000000000000000000000000000001387 159.0
HFD3_k127_7406591_7 ErfK ybiS ycfS ynhG family protein - - - 0.000000000000000000000000000000000003944 154.0
HFD3_k127_7406591_8 - - - - 0.000000000000000000000000000000008194 137.0
HFD3_k127_7406591_9 Protein of unknown function (DUF1569) - - - 0.000000000000000000000000004403 116.0
HFD3_k127_7442631_0 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 362.0
HFD3_k127_7442631_1 ADP-ribosylation factor family K06883 - - 0.00000000000000000000000000000000000000000000000000002609 189.0
HFD3_k127_7442631_2 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.00000000000002246 81.0
HFD3_k127_7442631_3 Virulence factor BrkB - - - 0.00000000000004578 83.0
HFD3_k127_7476471_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 3.711e-213 675.0
HFD3_k127_7476471_1 5'-nucleotidase, C-terminal domain K01119 - 3.1.3.6,3.1.4.16 5.553e-208 661.0
HFD3_k127_7476471_2 Acyl-CoA dehydrogenase, C-terminal domain K00248,K09478 - 1.3.8.1,1.3.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000782 552.0
HFD3_k127_7476471_3 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 428.0
HFD3_k127_7476471_4 Parallel beta-helix repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005966 353.0
HFD3_k127_7476471_5 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000001446 184.0
HFD3_k127_7476471_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K07027 - - 0.0000000007859 70.0
HFD3_k127_7499145_0 Sortilin, neurotensin receptor 3, - - - 0.0 1336.0
HFD3_k127_7499145_1 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000725 609.0
HFD3_k127_7499145_10 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 304.0
HFD3_k127_7499145_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002481 272.0
HFD3_k127_7499145_12 PFAM monooxygenase FAD-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000392 263.0
HFD3_k127_7499145_13 Glycosyl hydrolase family 9 K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000001278 227.0
HFD3_k127_7499145_14 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000004606 219.0
HFD3_k127_7499145_15 - - - - 0.0000000000000000000000000000000000000000001091 177.0
HFD3_k127_7499145_16 Transcriptional repressor, CopY family - - - 0.000000000000000000000000000000000000000001451 159.0
HFD3_k127_7499145_17 arogenate dehydratase activity K05359,K20102 GO:0003674,GO:0003824,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009314,GO:0009416,GO:0009507,GO:0009536,GO:0009628,GO:0009637,GO:0009642,GO:0009645,GO:0009987,GO:0010244,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0019438,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0047769,GO:0050896,GO:0071704,GO:0080167,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 4.2.1.51,4.2.1.91 0.0000000000000000000000000000000000000003232 158.0
HFD3_k127_7499145_18 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000000595 150.0
HFD3_k127_7499145_19 Thiol-disulfide oxidoreductase DCC - - - 0.000000000000000000000000000000000003036 141.0
HFD3_k127_7499145_2 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 591.0
HFD3_k127_7499145_20 PFAM Chorismate mutase, type II - - - 0.0000000000008661 71.0
HFD3_k127_7499145_21 - - - - 0.000000000007837 72.0
HFD3_k127_7499145_22 Transcriptional regulator K07979 - - 0.000000002085 61.0
HFD3_k127_7499145_3 Amidohydrolase family K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003759 596.0
HFD3_k127_7499145_4 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004154 544.0
HFD3_k127_7499145_5 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007123 460.0
HFD3_k127_7499145_6 Glycosyl hydrolase family 9 K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 433.0
HFD3_k127_7499145_7 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 404.0
HFD3_k127_7499145_8 COGs COG4299 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 380.0
HFD3_k127_7499145_9 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 371.0
HFD3_k127_7521245_0 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005905 568.0
HFD3_k127_7521245_1 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 506.0
HFD3_k127_7521245_2 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000001194 230.0
HFD3_k127_7521245_3 lactate metabolic process K11473 - - 0.000004425 49.0
HFD3_k127_7532271_0 TIGRFAM magnesium chelatase, H subunit K03403 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 529.0
HFD3_k127_7532271_1 Domain of unknown function (DUF3479) K03403 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006236 528.0
HFD3_k127_7532271_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 471.0
HFD3_k127_7532271_3 oxidoreductase activity, acting on diphenols and related substances as donors K02636,K03886 - 1.10.9.1 0.00000000000000000000000000000000000000000000000000000000000000000006442 237.0
HFD3_k127_7532271_4 AAA domain (dynein-related subfamily) K03404,K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000003643 202.0
HFD3_k127_7532271_5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000000000000000000000000000000003335 184.0
HFD3_k127_7532271_6 cell redox homeostasis K03671 - - 0.00000000009722 66.0
HFD3_k127_7535497_0 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K08641,K11206 - 3.4.13.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005047 316.0
HFD3_k127_7535497_1 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000557 156.0
HFD3_k127_7535497_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000005654 80.0
HFD3_k127_7535497_3 membrane transporter protein - - - 0.000001997 58.0
HFD3_k127_7558995_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 4.602e-286 901.0
HFD3_k127_7558995_1 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 477.0
HFD3_k127_7558995_10 Protein of unknown function with PCYCGC motif - - - 0.00000000000000002335 88.0
HFD3_k127_7558995_11 Tetratricopeptide repeat - - - 0.00000001356 67.0
HFD3_k127_7558995_12 Copper binding periplasmic protein CusF - - - 0.00000001412 60.0
HFD3_k127_7558995_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 467.0
HFD3_k127_7558995_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 399.0
HFD3_k127_7558995_4 copper resistance - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 329.0
HFD3_k127_7558995_5 PFAM Peptidase M19, renal dipeptidase K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 325.0
HFD3_k127_7558995_6 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000009001 231.0
HFD3_k127_7558995_7 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000002695 215.0
HFD3_k127_7558995_8 - - - - 0.00000000000000000000000000000002621 143.0
HFD3_k127_7558995_9 cell redox homeostasis K03671 - - 0.0000000000000000000004027 104.0
HFD3_k127_7593993_0 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006294 486.0
HFD3_k127_7593993_1 surface antigen variable number - - - 0.0000000000000000000000000000000000000000000000000000000000000227 245.0
HFD3_k127_7593993_2 Patatin-like phospholipase K07001 GO:0003674,GO:0003824,GO:0016787 - 0.00000000000000000000000000000000000000000000000324 183.0
HFD3_k127_7593993_3 Belongs to the multicopper oxidase YfiH RL5 family K05810 GO:0003674,GO:0005488,GO:0005507,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.0000000000000000000000000000000000000000002987 170.0
HFD3_k127_7593993_4 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000004098 109.0
HFD3_k127_7593993_5 Cytochrome c biogenesis protein transmembrane region K04084 - 1.8.1.8 0.00000000000004963 77.0
HFD3_k127_7593993_6 protein conserved in bacteria K09800 - - 0.0000000000006847 81.0
HFD3_k127_7593993_7 peptidylprolyl isomerase K03771 - 5.2.1.8 0.000000001022 68.0
HFD3_k127_7658711_0 Domain of unknown function (DUF5110) K01187 - 3.2.1.20 5.219e-201 652.0
HFD3_k127_7658711_1 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000001226 222.0
HFD3_k127_7695694_0 DEAD DEAH box helicase K03724 - - 0.0 1738.0
HFD3_k127_7695694_1 metallocarboxypeptidase activity K14054 - - 8.831e-287 913.0
HFD3_k127_7695694_10 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005285 362.0
HFD3_k127_7695694_11 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006331 305.0
HFD3_k127_7695694_12 Homoserine dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001865 276.0
HFD3_k127_7695694_13 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004623 271.0
HFD3_k127_7695694_14 Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000001528 261.0
HFD3_k127_7695694_15 helix_turn_helix gluconate operon transcriptional repressor K07978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001937 249.0
HFD3_k127_7695694_16 Xylose isomerase-like TIM barrel K06606 - 5.3.99.11 0.000000000000000000000000000000000000000000000000000000000000000001786 235.0
HFD3_k127_7695694_17 Aerotolerance regulator N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000008946 243.0
HFD3_k127_7695694_18 Belongs to the UPF0502 family K09915 - - 0.000000000000000000000000000000000000000000000000000000008006 205.0
HFD3_k127_7695694_19 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000007328 199.0
HFD3_k127_7695694_2 metalloendopeptidase activity K01283 - 3.4.15.1 4.033e-257 805.0
HFD3_k127_7695694_20 oxidoreductase activity K12511 - - 0.00000000000000000000000000000000000004621 156.0
HFD3_k127_7695694_21 metal cluster binding - - - 0.000000000000000000000000000000000002292 145.0
HFD3_k127_7695694_22 PFAM HNH endonuclease - - - 0.00000000000000000000000000000006028 133.0
HFD3_k127_7695694_23 Iron-binding zinc finger CDGSH type - - - 0.000000000000000000000002584 112.0
HFD3_k127_7695694_24 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000008499 87.0
HFD3_k127_7695694_3 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 607.0
HFD3_k127_7695694_4 family UPF0027 K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 530.0
HFD3_k127_7695694_5 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 474.0
HFD3_k127_7695694_6 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008161 502.0
HFD3_k127_7695694_7 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004146 420.0
HFD3_k127_7695694_8 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 422.0
HFD3_k127_7695694_9 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 360.0
HFD3_k127_777845_0 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.0 1128.0
HFD3_k127_777845_1 Phage tail protein (Tail_P2_I) - - - 2.05e-259 832.0
HFD3_k127_777845_10 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003202 299.0
HFD3_k127_777845_11 Macrocin-O-methyltransferase (TylF) K05303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003481 276.0
HFD3_k127_777845_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002392 253.0
HFD3_k127_777845_13 membrane - - - 0.0000000000000000000000000000000000000000000000000000001496 199.0
HFD3_k127_777845_14 GPW gp25 family protein K06903 - - 0.000000000000000000000000000000000000000000001911 167.0
HFD3_k127_777845_15 - - - - 0.0000000000000000000000000000000000000000005508 179.0
HFD3_k127_777845_16 HYR domain - - - 0.00000000000000000000000000000000000000003856 172.0
HFD3_k127_777845_17 - - - - 0.00000000000000000000000000000000004863 145.0
HFD3_k127_777845_18 - - - - 0.0000000000000000000000000000000002153 135.0
HFD3_k127_777845_19 Cephalosporin hydroxylase - - - 0.000000000000000000000000000001967 123.0
HFD3_k127_777845_2 phage tail tape measure protein - - - 8.532e-258 831.0
HFD3_k127_777845_20 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.00000000000000000000000001678 109.0
HFD3_k127_777845_22 Peptidase family M48 - - - 0.00000000000000000007037 101.0
HFD3_k127_777845_23 DinB superfamily - - - 0.0000000000000005996 84.0
HFD3_k127_777845_26 HicA toxin of bacterial toxin-antitoxin, - - - 0.000002935 51.0
HFD3_k127_777845_27 photosystem II stabilization K02237 - - 0.000003547 61.0
HFD3_k127_777845_28 - - - - 0.00002396 52.0
HFD3_k127_777845_29 Clp amino terminal domain, pathogenicity island component - - - 0.00005736 46.0
HFD3_k127_777845_3 Baseplate J-like protein - - - 1.607e-256 812.0
HFD3_k127_777845_30 Glycosyl hydrolase 101 beta sandwich domain - - - 0.0004828 53.0
HFD3_k127_777845_4 ATPase family associated with various cellular activities (AAA) - - - 3.92e-212 680.0
HFD3_k127_777845_5 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 622.0
HFD3_k127_777845_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 415.0
HFD3_k127_777845_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007707 342.0
HFD3_k127_777845_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004469 321.0
HFD3_k127_777845_9 PFAM Phage integrase, N-terminal SAM-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 302.0
HFD3_k127_801165_0 in Yersinia the HmsR protein is an inner membrane protein K11936 - - 0.0 1149.0
HFD3_k127_801165_1 4Fe-4S dicluster domain K00184 - - 0.0 1054.0
HFD3_k127_801165_10 Sodium:dicarboxylate symporter family K03309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005999 398.0
HFD3_k127_801165_11 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 383.0
HFD3_k127_801165_12 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007331 369.0
HFD3_k127_801165_13 signal sequence binding K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 299.0
HFD3_k127_801165_14 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 293.0
HFD3_k127_801165_15 GHMP kinases C terminal K07031 - 2.7.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004202 286.0
HFD3_k127_801165_16 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004515 280.0
HFD3_k127_801165_17 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008205 268.0
HFD3_k127_801165_18 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000005887 268.0
HFD3_k127_801165_19 PFAM cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000004334 259.0
HFD3_k127_801165_2 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 4.667e-277 860.0
HFD3_k127_801165_20 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000000000000000000000000000000007795 222.0
HFD3_k127_801165_21 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000008035 222.0
HFD3_k127_801165_22 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000005685 227.0
HFD3_k127_801165_23 spore germination - - - 0.000000000000000000000000000000000000000000000000000000004857 209.0
HFD3_k127_801165_24 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000001379 198.0
HFD3_k127_801165_25 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000003169 193.0
HFD3_k127_801165_26 - - - - 0.00000000000000000000000000000000000000000000000002377 187.0
HFD3_k127_801165_27 PFAM metallophosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000001984 181.0
HFD3_k127_801165_28 Phosphoribosyl transferase domain K00762 - 2.4.2.10 0.00000000000000000000000000000000000000001304 160.0
HFD3_k127_801165_29 PFAM Histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000000000001005 151.0
HFD3_k127_801165_3 Polysulphide reductase, NrfD K00185 - - 2.44e-219 688.0
HFD3_k127_801165_30 Ferredoxin K00529,K04755,K08952,K08953,K08954,K15765 GO:0005575,GO:0005622,GO:0005623,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0046858 1.18.1.3 0.000000000000000000000000000000003519 141.0
HFD3_k127_801165_31 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000009619 112.0
HFD3_k127_801165_32 palmitoyl-(protein) hydrolase activity K06999 - - 0.00000000000000000000000007413 118.0
HFD3_k127_801165_33 PFAM UspA domain protein K06149 - - 0.00000000000000000000000008331 113.0
HFD3_k127_801165_34 TIGRFAM Caa(3)-type oxidase, subunit IV K02277 - 1.9.3.1 0.0000000000000000000001336 100.0
HFD3_k127_801165_35 Putative restriction endonuclease - - - 0.00000000000000000003365 97.0
HFD3_k127_801165_36 Belongs to the Nudix hydrolase family - - - 0.0000000000000000232 87.0
HFD3_k127_801165_37 Membrane - GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0032505,GO:0043093,GO:0044464,GO:0051301,GO:0071944 - 0.0000000000000004323 87.0
HFD3_k127_801165_38 Domain of unknown function (DUF4440) - - - 0.000005409 56.0
HFD3_k127_801165_4 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 3.86e-217 691.0
HFD3_k127_801165_5 Phosphoenolpyruvate carboxykinase K01610 - 4.1.1.49 2.814e-206 654.0
HFD3_k127_801165_6 Amidohydrolase family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 534.0
HFD3_k127_801165_7 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 484.0
HFD3_k127_801165_8 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 445.0
HFD3_k127_801165_9 PFAM amino acid permease-associated region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009604 400.0
HFD3_k127_802458_0 Amidohydrolase family K01464 - 3.5.2.2 1.422e-201 636.0
HFD3_k127_802458_1 PFAM Permease for cytosine purines, uracil, thiamine, allantoin K03457 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 597.0
HFD3_k127_802458_2 PFAM Peptidase S10, serine carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 553.0
HFD3_k127_802458_3 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 461.0
HFD3_k127_802458_4 4Fe-4S dicluster domain K17723 - 1.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 437.0
HFD3_k127_802458_5 Exodeoxyribonuclease iii K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000002697 224.0
HFD3_k127_802458_7 Belongs to the aldehyde dehydrogenase family K22187 - - 0.00000000000000000000000001626 110.0
HFD3_k127_806875_0 PAS domain K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000007325 99.0
HFD3_k127_806875_2 - K07018 - - 0.00000000000000006049 82.0
HFD3_k127_806875_3 Zinc-binding dehydrogenase - - - 0.00000000000000006739 81.0
HFD3_k127_808272_0 PFAM type II secretion system protein E K02283,K03609 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007522 572.0
HFD3_k127_808272_1 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009939 340.0
HFD3_k127_808272_11 PFAM peptidase A24A, prepilin type IV - - - 0.00000000000000002174 88.0
HFD3_k127_808272_12 TadE-like protein - - - 0.0000000000004797 76.0
HFD3_k127_808272_13 TadE-like protein - - - 0.000000000002234 74.0
HFD3_k127_808272_14 Tetratricopeptide repeat - - - 0.0000009467 60.0
HFD3_k127_808272_2 Belongs to the GSP D family K02280 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001472 289.0
HFD3_k127_808272_3 Type II secretion system K12510 - - 0.00000000000000000000000000000000000000000000000000000001083 211.0
HFD3_k127_808272_4 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.00000000000000000000000000000000000000000000000000009471 197.0
HFD3_k127_808272_5 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000002368 199.0
HFD3_k127_808272_6 Type II secretion system (T2SS), protein F K12511 - - 0.0000000000000000000000000000000000000000000000004168 188.0
HFD3_k127_808272_7 PFAM Lytic transglycosylase catalytic K08309 - - 0.00000000000000000000000000000000002143 147.0
HFD3_k127_808272_8 oxidoreductase activity K07114,K12511 - - 0.0000000000000000000000001162 120.0
HFD3_k127_808272_9 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000000000000003823 104.0
HFD3_k127_83152_0 Dipeptidyl peptidase IV (DPP IV) N-terminal region - - - 5.313e-296 925.0
HFD3_k127_83152_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 563.0
HFD3_k127_83152_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006179 317.0
HFD3_k127_83152_11 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000002052 252.0
HFD3_k127_83152_12 Belongs to the TrpC family K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000138 229.0
HFD3_k127_83152_13 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000007641 207.0
HFD3_k127_83152_14 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000355 203.0
HFD3_k127_83152_15 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000001245 186.0
HFD3_k127_83152_16 diguanylate cyclase - - - 0.0000000000000000000000000000000000003178 153.0
HFD3_k127_83152_2 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004762 574.0
HFD3_k127_83152_3 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007537 517.0
HFD3_k127_83152_4 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 492.0
HFD3_k127_83152_5 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 482.0
HFD3_k127_83152_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004186 375.0
HFD3_k127_83152_7 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009567 380.0
HFD3_k127_83152_8 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000345 352.0
HFD3_k127_83152_9 beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 342.0
HFD3_k127_867484_0 Cytochrome c - - - 0.0 1242.0
HFD3_k127_867484_1 GMC oxidoreductase - - - 1.7e-287 893.0
HFD3_k127_867484_10 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005034 408.0
HFD3_k127_867484_11 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 395.0
HFD3_k127_867484_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000007424 227.0
HFD3_k127_867484_13 - - - - 0.000000000000000000000000000000000000000000000000000000000001917 211.0
HFD3_k127_867484_14 Protein of unknown function (DUF3179) - - - 0.0000000000000000000000000000000000000000000000000000000009603 209.0
HFD3_k127_867484_15 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000003947 194.0
HFD3_k127_867484_16 - - - - 0.000000000000000000000000000000000000000003372 157.0
HFD3_k127_867484_17 PFAM peptidase M15B and M15C DD-carboxypeptidase VanY endolysin - - - 0.0000000000000000000000000001321 126.0
HFD3_k127_867484_18 Protein of unknown function with PCYCGC motif - - - 0.000000000000000000005414 96.0
HFD3_k127_867484_2 iron assimilation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004211 614.0
HFD3_k127_867484_20 YtkA-like - - - 0.0000000000000003155 85.0
HFD3_k127_867484_22 membrane - - - 0.0002886 51.0
HFD3_k127_867484_23 Transglycosylase SLT domain - - - 0.0008485 51.0
HFD3_k127_867484_3 catalase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005008 582.0
HFD3_k127_867484_4 Belongs to the aldehyde dehydrogenase family K00141,K22187 - 1.2.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 584.0
HFD3_k127_867484_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 537.0
HFD3_k127_867484_6 PFAM TonB-dependent Receptor Plug - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 560.0
HFD3_k127_867484_7 Winged helix DNA-binding domain K09927 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 500.0
HFD3_k127_867484_8 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 496.0
HFD3_k127_867484_9 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008949 467.0
HFD3_k127_884814_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 7.82e-302 947.0
HFD3_k127_884814_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.937e-213 685.0
HFD3_k127_884814_10 Peptidase, M28 - - - 0.000000000000000000002524 102.0
HFD3_k127_884814_11 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000007252 89.0
HFD3_k127_884814_12 CS domain K13993 - - 0.000000000002635 73.0
HFD3_k127_884814_13 - - - - 0.0000000004698 64.0
HFD3_k127_884814_14 Domain of unknown function (DUF4956) - - - 0.000000004329 68.0
HFD3_k127_884814_15 Putative adhesin - - - 0.000000009663 65.0
HFD3_k127_884814_16 Tyrosine phosphatase family - - - 0.00001411 55.0
HFD3_k127_884814_17 - - - - 0.00003452 55.0
HFD3_k127_884814_18 Putative zinc-finger K03088 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0001352 52.0
HFD3_k127_884814_19 Putative zinc-finger - - - 0.0001534 52.0
HFD3_k127_884814_2 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 553.0
HFD3_k127_884814_3 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005849 362.0
HFD3_k127_884814_4 Lysin motif K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000038 274.0
HFD3_k127_884814_5 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000000234 220.0
HFD3_k127_884814_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000003227 216.0
HFD3_k127_884814_7 - - - - 0.00000000000000000000000000000000000000000000000000001982 201.0
HFD3_k127_884814_8 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000000000002494 176.0
HFD3_k127_884814_9 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000005082 155.0
HFD3_k127_890502_0 Carboxypeptidase regulatory-like domain - - - 0.0 1480.0
HFD3_k127_890502_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1156.0
HFD3_k127_890502_10 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005903 279.0
HFD3_k127_890502_11 Pyruvate phosphate dikinase - - - 0.0000000000000000000000000000000000000000000000000000000000000008381 224.0
HFD3_k127_890502_12 DNA-templated transcription, initiation K02405 - - 0.000000000000000000000000000000000000000000000000000003005 196.0
HFD3_k127_890502_13 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000001677 190.0
HFD3_k127_890502_14 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000000001538 187.0
HFD3_k127_890502_15 - - - - 0.00000000000000000000000000000000000000001124 164.0
HFD3_k127_890502_16 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.000000000000000000000000000000000000004165 152.0
HFD3_k127_890502_17 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000002381 138.0
HFD3_k127_890502_18 Yqey-like protein K09117 - - 0.000000000000000000000000000000001098 136.0
HFD3_k127_890502_19 Tetratricopeptide repeat - - - 0.000000000000000000000000000000002107 139.0
HFD3_k127_890502_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.093e-222 720.0
HFD3_k127_890502_20 metallopeptidase activity - - - 0.000000000000000000000000000000815 132.0
HFD3_k127_890502_21 von Willebrand factor (vWF) type A domain K07114 - - 0.00000000000000000000008704 111.0
HFD3_k127_890502_22 Penicillinase repressor - - - 0.000000000000000000000115 103.0
HFD3_k127_890502_23 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000001979 81.0
HFD3_k127_890502_24 - - - - 0.00000000000002628 76.0
HFD3_k127_890502_25 C-3'',4'' desaturase CrtD - - - 0.00000000000002862 85.0
HFD3_k127_890502_26 TonB dependent receptor K16087 - - 0.00000000000004856 87.0
HFD3_k127_890502_27 - - - - 0.000000000004366 74.0
HFD3_k127_890502_28 peptidase M48, Ste24p - - - 0.0001692 53.0
HFD3_k127_890502_29 PFAM Abortive infection protein K07052 - - 0.0001936 52.0
HFD3_k127_890502_3 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 554.0
HFD3_k127_890502_4 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 384.0
HFD3_k127_890502_5 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009503 356.0
HFD3_k127_890502_6 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 338.0
HFD3_k127_890502_7 Molybdenum cofactor synthesis domain protein K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 295.0
HFD3_k127_890502_8 PFAM Mur ligase K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000271 280.0
HFD3_k127_890502_9 DHH family K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000001473 274.0
HFD3_k127_902756_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 574.0
HFD3_k127_902756_1 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 577.0
HFD3_k127_902756_10 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003753 326.0
HFD3_k127_902756_11 PFAM polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002325 282.0
HFD3_k127_902756_12 Phosphoesterase family K21302 - 3.1.3.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000002294 296.0
HFD3_k127_902756_13 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001646 286.0
HFD3_k127_902756_14 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001416 282.0
HFD3_k127_902756_15 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000241 252.0
HFD3_k127_902756_16 eight transmembrane protein EpsH - - - 0.0000000000000000000000000000000000000000000000000000000000000001506 233.0
HFD3_k127_902756_17 AAA domain K02450 - - 0.000000000000000000000000000000000000000000000000000000000000002937 228.0
HFD3_k127_902756_18 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000002365 194.0
HFD3_k127_902756_19 Photosynthesis system II assembly factor YCF48 - - - 0.0000000000000000000000000000000000000000000000002232 190.0
HFD3_k127_902756_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009753 537.0
HFD3_k127_902756_20 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000003715 188.0
HFD3_k127_902756_21 Nucleotidyl transferase - - - 0.00000000000000000000000000000000000000000000003414 179.0
HFD3_k127_902756_22 PFAM Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000003293 164.0
HFD3_k127_902756_23 Protein of unknown function (DUF3485) - - - 0.00000000000000000000000000000000000002271 152.0
HFD3_k127_902756_24 Capsular exopolysaccharide family K08252 - 2.7.10.1 0.00000000000000000000000000000000000002853 157.0
HFD3_k127_902756_25 Chain length determinant protein - - - 0.000000000000000000000000000000001361 147.0
HFD3_k127_902756_26 aminoglycoside 3-N-acetyltransferase K00662 - 2.3.1.81 0.000000000000000000000000000002643 131.0
HFD3_k127_902756_27 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000254 127.0
HFD3_k127_902756_28 Belongs to the glycosyl hydrolase family 6 K19668 - 3.2.1.91 0.00000000000000000006955 106.0
HFD3_k127_902756_3 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005329 534.0
HFD3_k127_902756_30 6-phosphogluconolactonase activity - - - 0.000000000000000006169 100.0
HFD3_k127_902756_31 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase - - - 0.00000000000000004834 94.0
HFD3_k127_902756_32 Cellulase (glycosyl hydrolase family 5) K01179 - 3.2.1.4 0.000000000000000661 94.0
HFD3_k127_902756_33 PFAM Polysaccharide export protein K01991 - - 0.00000000000001488 85.0
HFD3_k127_902756_34 Alpha-L-rhamnosidase - - - 0.0000000000002011 85.0
HFD3_k127_902756_35 Methyltransferase type 11 - - - 0.0000000000002637 78.0
HFD3_k127_902756_36 Cadherin-like beta sandwich domain - - - 0.0000000000003684 85.0
HFD3_k127_902756_37 DUF218 domain - - - 0.0000000000008534 76.0
HFD3_k127_902756_38 PFAM MCP methyltransferase CheR-type K00575 - 2.1.1.80 0.000002699 60.0
HFD3_k127_902756_4 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 485.0
HFD3_k127_902756_5 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 382.0
HFD3_k127_902756_6 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 370.0
HFD3_k127_902756_7 transferase activity, transferring glycosyl groups K16150 - 2.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006795 373.0
HFD3_k127_902756_8 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009501 356.0
HFD3_k127_902756_9 Heparinase II/III-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 346.0
HFD3_k127_92631_0 Glycogen debranching enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007748 498.0
HFD3_k127_92631_1 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009145 411.0
HFD3_k127_92631_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000007562 221.0
HFD3_k127_92631_3 Acyl-transferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000004295 185.0
HFD3_k127_92631_4 Transport and Golgi organisation 2 - - - 0.00000000000000000000000000000000002321 145.0
HFD3_k127_92631_5 DinB family - - - 0.000000000000000000000004675 109.0
HFD3_k127_934718_0 PLD-like domain K06131 - - 1.022e-218 689.0
HFD3_k127_934718_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 486.0
HFD3_k127_934718_10 CheC inhibitor of MCP methylation K03410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001597 247.0
HFD3_k127_934718_11 Response regulator receiver domain K03413 - - 0.000000000000000000000000000000000001375 141.0
HFD3_k127_934718_12 hmm pf03415 K08587 - 3.4.22.8 0.00000000000000000004089 104.0
HFD3_k127_934718_14 - - - - 0.00000001288 66.0
HFD3_k127_934718_15 Patatin-like phospholipase K06900 - - 0.00000001548 62.0
HFD3_k127_934718_16 Esterase PHB depolymerase - - - 0.00000375 57.0
HFD3_k127_934718_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004758 468.0
HFD3_k127_934718_3 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 469.0
HFD3_k127_934718_4 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 456.0
HFD3_k127_934718_5 alcohol dehydrogenase K00001,K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 448.0
HFD3_k127_934718_6 Methyltransferase, chemotaxis proteins K00575,K13486 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 325.0
HFD3_k127_934718_7 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006476 273.0
HFD3_k127_934718_8 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004138 263.0
HFD3_k127_934718_9 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006496 272.0
HFD3_k127_935503_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007723 497.0
HFD3_k127_935503_1 RmlD substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 428.0
HFD3_k127_935503_10 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000001265 156.0
HFD3_k127_935503_11 - - - - 0.000000000000000000000000000000001784 144.0
HFD3_k127_935503_12 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000004047 117.0
HFD3_k127_935503_13 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000001536 96.0
HFD3_k127_935503_14 KH domain K06960 - - 0.000000000000002187 78.0
HFD3_k127_935503_15 Pfam Glycosyl transferase family 2 K10012 - 2.4.2.53 0.0003157 46.0
HFD3_k127_935503_2 Domain of unknown function (DUF1972) K12996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 406.0
HFD3_k127_935503_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 355.0
HFD3_k127_935503_4 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 370.0
HFD3_k127_935503_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009085 297.0
HFD3_k127_935503_6 Glycosyl transferases group 1 K12994 - 2.4.1.349 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009752 279.0
HFD3_k127_935503_7 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002593 271.0
HFD3_k127_935503_8 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000004825 228.0
HFD3_k127_935503_9 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000002488 236.0
HFD3_k127_938587_0 cellulose binding - - - 4.222e-294 936.0
HFD3_k127_938587_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 2.872e-231 728.0
HFD3_k127_938587_10 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008175 401.0
HFD3_k127_938587_11 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 371.0
HFD3_k127_938587_12 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 363.0
HFD3_k127_938587_13 SMART PUA domain containing protein K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 362.0
HFD3_k127_938587_14 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 357.0
HFD3_k127_938587_15 COGs COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 346.0
HFD3_k127_938587_16 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 334.0
HFD3_k127_938587_17 Belongs to the ATCase OTCase family K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0043857,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 336.0
HFD3_k127_938587_18 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004014 334.0
HFD3_k127_938587_19 Branched-chain amino acid transport system / permease component K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 329.0
HFD3_k127_938587_2 TIGRFAM methylmalonyl-CoA mutase, large subunit K01847,K01848 - 5.4.99.2 2.814e-229 722.0
HFD3_k127_938587_20 polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006793 325.0
HFD3_k127_938587_21 Branched-chain amino acid ATP-binding cassette transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008466 314.0
HFD3_k127_938587_22 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 322.0
HFD3_k127_938587_23 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 319.0
HFD3_k127_938587_24 ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 295.0
HFD3_k127_938587_25 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 310.0
HFD3_k127_938587_26 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006361 290.0
HFD3_k127_938587_27 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000032 284.0
HFD3_k127_938587_28 Mo-molybdopterin cofactor biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000306 280.0
HFD3_k127_938587_29 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000009707 258.0
HFD3_k127_938587_3 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 584.0
HFD3_k127_938587_30 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000001294 255.0
HFD3_k127_938587_31 Pfam Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003519 240.0
HFD3_k127_938587_32 COG0515 Serine threonine protein K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000002437 238.0
HFD3_k127_938587_33 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000003507 219.0
HFD3_k127_938587_34 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000000001684 218.0
HFD3_k127_938587_35 PQQ-like domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000008241 226.0
HFD3_k127_938587_36 Biotin-lipoyl like K02005 - - 0.0000000000000000000000000000000000000000000000000003402 203.0
HFD3_k127_938587_37 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000004513 166.0
HFD3_k127_938587_38 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000001729 123.0
HFD3_k127_938587_4 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782 567.0
HFD3_k127_938587_40 - - - - 0.00000000000000000000000001469 117.0
HFD3_k127_938587_41 DNA polymerase K02347 - - 0.00000000000000000000000003818 113.0
HFD3_k127_938587_42 PFAM Forkhead-associated protein - - - 0.0000000000000000000008431 102.0
HFD3_k127_938587_43 Transcriptional K07979 - - 0.0000000000000000000009303 98.0
HFD3_k127_938587_44 Yip1 domain - - - 0.0000000000000000001827 98.0
HFD3_k127_938587_45 Regulates arginine biosynthesis genes K03402 - - 0.000000000000000002652 89.0
HFD3_k127_938587_46 Gram-negative bacterial TonB protein C-terminal - - - 0.00000000004259 73.0
HFD3_k127_938587_47 Protein of unknown function (DUF983) - - - 0.0000000002707 67.0
HFD3_k127_938587_48 RDD family - - - 0.000000001167 65.0
HFD3_k127_938587_49 TIGRFAM TonB - - - 0.0000002557 61.0
HFD3_k127_938587_5 argininosuccinate lyase K01755,K14681 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004192 505.0
HFD3_k127_938587_6 Peptidase, S9A B C family, catalytic domain protein K01303 - 3.4.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 501.0
HFD3_k127_938587_7 asparaginase K01424,K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.1,3.5.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 459.0
HFD3_k127_938587_8 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006599 438.0
HFD3_k127_938587_9 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 406.0
HFD3_k127_99698_0 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 364.0
HFD3_k127_99698_1 Copper/zinc superoxide dismutase (SODC) K04565 - 1.15.1.1 0.000000000000000000000000000000000000000000000000003146 187.0
HFD3_k127_998694_0 COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component K09014 - - 7.164e-256 794.0
HFD3_k127_998694_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007505 586.0
HFD3_k127_998694_10 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 328.0
HFD3_k127_998694_11 neuron death in response to oxidative stress K01173,K07004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 358.0
HFD3_k127_998694_12 PFAM Branched-chain amino acid transport system permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009915 302.0
HFD3_k127_998694_13 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002091 287.0
HFD3_k127_998694_14 Peptidase dimerisation domain K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003932 289.0
HFD3_k127_998694_15 DNA/RNA non-specific endonuclease K01173 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002572 290.0
HFD3_k127_998694_16 Phosphoribulokinase / Uridine kinase family K00855,K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.19,2.7.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000001633 256.0
HFD3_k127_998694_17 PFAM Endonuclease Exonuclease phosphatase K07004 - - 0.0000000000000000000000000000000000000000000000000000006331 222.0
HFD3_k127_998694_18 NifU-like N terminal domain K04488 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 - 0.000000000000000000000000000000000000000000000000000001083 196.0
HFD3_k127_998694_19 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000005393 176.0
HFD3_k127_998694_2 ABC transporter K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 533.0
HFD3_k127_998694_20 domain protein - - - 0.00000000000000000000000000000000000000000000002128 198.0
HFD3_k127_998694_21 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.00000000000000000000000000000000000000000005811 164.0
HFD3_k127_998694_22 domain protein - - - 0.0000000000000000000000000000000000000007848 173.0
HFD3_k127_998694_23 Exodeoxyribonuclease iii K01142 - 3.1.11.2 0.0000000000000000000000000000000000002472 144.0
HFD3_k127_998694_24 Lamin Tail Domain - - - 0.00000000000000000000000000000000001208 159.0
HFD3_k127_998694_25 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.00000000000000000000000000000001038 132.0
HFD3_k127_998694_26 transcriptional regulator - - - 0.0000000000000000000000001348 111.0
HFD3_k127_998694_27 Peptidase, M56 - - - 0.000000923 61.0
HFD3_k127_998694_3 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005637 484.0
HFD3_k127_998694_4 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005114 456.0
HFD3_k127_998694_5 PFAM Glycosyl transferase, family K00756 - 2.4.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007306 417.0
HFD3_k127_998694_6 ATPase activity K09013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006501 380.0
HFD3_k127_998694_7 Uncharacterized protein family (UPF0051) K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006313 361.0
HFD3_k127_998694_8 PFAM Endonuclease Exonuclease phosphatase K07004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 368.0
HFD3_k127_998694_9 PFAM Basic membrane lipoprotein K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007905 334.0