Overview

ID MAG01695
Name HFD3_bin.39
Sample SMP0045
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class UBA9217
Order UBA9217
Family UBA9217
Genus DASPSR01
Species
Assembly information
Completeness (%) 86.5
Contamination (%) 3.25
GC content (%) 52.0
N50 (bp) 9,287
Genome size (bp) 3,171,113

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2943

Gene name Description KEGG GOs EC E-value Score Sequence
HFD3_k127_100537_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.000000000000000000000000000000000000000000000000000000000000003713 222.0
HFD3_k127_100537_1 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000008893 204.0
HFD3_k127_100537_2 Binds directly to 16S ribosomal RNA K02968 - - 0.0000002157 54.0
HFD3_k127_1014515_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006198 410.0
HFD3_k127_1014515_1 metal-dependent phosphohydrolase 7TM intracellular region K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 391.0
HFD3_k127_1014515_10 Pfam:DUF461 K09796 - - 0.0002651 49.0
HFD3_k127_1014515_2 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 363.0
HFD3_k127_1014515_3 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.0000000000000000000000000000000000000000000000000001337 194.0
HFD3_k127_1014515_4 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000002494 115.0
HFD3_k127_1014515_5 response regulator, receiver - - - 0.000000000000979 77.0
HFD3_k127_1014515_6 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain K02488 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 0.000000000726 69.0
HFD3_k127_1014515_7 Roadblock/LC7 domain - - - 0.00000001025 61.0
HFD3_k127_1014515_8 phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.00000004907 63.0
HFD3_k127_1014515_9 phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.0000003236 61.0
HFD3_k127_1020036_0 DnaJ molecular chaperone homology domain K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000001469 237.0
HFD3_k127_1020036_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.0000000000000000000000000000000000000000000000000000301 192.0
HFD3_k127_1020036_2 PIN domain K19686 - - 0.00000000000000000000000000000000000000000000000005239 181.0
HFD3_k127_1020036_3 toxin-antitoxin pair type II binding - - - 0.0000000000000000000000000001699 116.0
HFD3_k127_1020036_4 Periplasmic binding protein domain K10439 - - 0.00000000001647 65.0
HFD3_k127_103042_0 DEAD DEAH box K03724 - - 1.981e-235 739.0
HFD3_k127_103042_1 Transposase K07496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003602 282.0
HFD3_k127_103042_2 Transposase K07496 - - 0.000000000000000000000004691 104.0
HFD3_k127_103042_3 Transposase IS200 like K07491 - - 0.000000001212 59.0
HFD3_k127_1037548_0 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 367.0
HFD3_k127_1037548_1 response regulator K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005335 275.0
HFD3_k127_1037548_2 Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA. It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base. The complementary strand guanine functions in substrate recognition. Required for DNA damage lesion repair in stationary-phase cells K03649 - 3.2.2.28 0.000000000000000000000000000000000000000000000000000000000000000002761 233.0
HFD3_k127_1037548_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000008011 178.0
HFD3_k127_1037548_4 Integrase core domain - - - 0.000000000000000000000005707 102.0
HFD3_k127_1039723_0 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 297.0
HFD3_k127_1039723_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001145 265.0
HFD3_k127_1039723_2 lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000002221 259.0
HFD3_k127_1039723_3 Psort location Cytoplasmic, score - - - 0.000008518 51.0
HFD3_k127_1041481_0 4 iron, 4 sulfur cluster binding K07139 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051539,GO:0051540 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003594 396.0
HFD3_k127_1041481_1 Lytic transglycosylase, SLT, LysM and LysM domain-containing K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 356.0
HFD3_k127_1041481_2 DNA polymerase alpha chain like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008898 260.0
HFD3_k127_1041481_3 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.000000000000000000000000000000000000000000000000000000000000000001032 246.0
HFD3_k127_1041481_4 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000001138 184.0
HFD3_k127_1041481_5 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.0000000000000000001819 89.0
HFD3_k127_1041481_6 protein related to C-terminal domain of eukaryotic chaperone SACSIN - - - 0.00001349 52.0
HFD3_k127_1041481_7 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.00009384 47.0
HFD3_k127_1041481_8 Tetratricopeptide repeat protein - - - 0.0001904 52.0
HFD3_k127_1047563_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 372.0
HFD3_k127_1047563_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 315.0
HFD3_k127_1047563_2 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000001222 217.0
HFD3_k127_1047563_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000002127 79.0
HFD3_k127_10527_0 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 380.0
HFD3_k127_10527_1 (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005992 295.0
HFD3_k127_10527_2 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 295.0
HFD3_k127_10527_3 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000001695 218.0
HFD3_k127_10527_4 GIY-YIG catalytic domain K07461 - - 0.000009598 50.0
HFD3_k127_1058348_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007381 406.0
HFD3_k127_1058348_1 Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides K13014 GO:0005575,GO:0008150,GO:0010035,GO:0010038,GO:0010039,GO:0010041,GO:0016020,GO:0042221,GO:0050896 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 374.0
HFD3_k127_1058348_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000008661 71.0
HFD3_k127_1058348_3 3-beta hydroxysteroid dehydrogenase/isomerase family K10011,K12449 - 1.1.1.305,2.1.2.13 0.00008702 45.0
HFD3_k127_1072141_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 488.0
HFD3_k127_1072141_1 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 396.0
HFD3_k127_1072141_2 6 heme-binding sites - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 323.0
HFD3_k127_1072141_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000569 333.0
HFD3_k127_1072141_4 Putative bacterial lipoprotein (DUF799) - - - 0.000000000000000000000000000000000000000000000000000000000000000204 225.0
HFD3_k127_1072141_5 amine dehydrogenase activity - - - 0.00000000000000000000000000003214 119.0
HFD3_k127_1072141_6 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000001901 112.0
HFD3_k127_1076439_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 519.0
HFD3_k127_1076439_1 NADPH-quinone reductase (modulator of drug activity B) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 308.0
HFD3_k127_1076439_10 PFAM FecR protein - - - 0.0002366 51.0
HFD3_k127_1076439_2 peptidase U32 - - - 0.0000000000000000000000000000000000000000000000000000000000001285 215.0
HFD3_k127_1076439_4 binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription this protein is involved in detoxification and protection against antimicrobial K03088 - - 0.0000000000000000000000000000000009289 137.0
HFD3_k127_1076439_5 1,4-alpha-glucan branching enzyme activity K00700 - 2.4.1.18 0.00000000000000000000000007287 115.0
HFD3_k127_1076439_6 1,4-alpha-glucan branching enzyme activity K00700 - 2.4.1.18 0.00000000000000000001993 95.0
HFD3_k127_1076439_7 Outer membrane lipoprotein Slp family K07285 - - 0.000000000000000000361 93.0
HFD3_k127_1076439_9 - - - - 0.000008958 57.0
HFD3_k127_1094645_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299 - 1.17.1.10,1.17.1.9 1.09e-215 684.0
HFD3_k127_1094645_1 Sulfite reductase, subunit A - - - 0.00000000000000000000000000000000000000000000000000000000000000000001248 245.0
HFD3_k127_1096958_0 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 368.0
HFD3_k127_1096958_1 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000003743 158.0
HFD3_k127_1096958_2 amine dehydrogenase activity - - - 0.0000000000000000000001895 103.0
HFD3_k127_1096958_3 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000003203 74.0
HFD3_k127_1096958_4 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000001275 62.0
HFD3_k127_1096958_5 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0001766 51.0
HFD3_k127_1106025_0 Conserved protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001553 240.0
HFD3_k127_1106025_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000002188 218.0
HFD3_k127_1106025_2 Zgc 162297 K06971 - - 0.00000000000000000000000000000000000000000000000000000000005042 214.0
HFD3_k127_1106025_3 Acetyltransferase (GNAT) domain - - - 0.000000633 58.0
HFD3_k127_1106025_4 Protein of unknown function (DUF3887) - - - 0.00002678 52.0
HFD3_k127_118624_0 Cation efflux family - - - 0.00000000000000000000000000000000000000000001015 165.0
HFD3_k127_118624_1 FAD binding domain - - - 0.00000000000000000000000000000000000000003127 162.0
HFD3_k127_118624_2 PFAM PHP domain - - - 0.00000000000000000000000000000000000000005546 159.0
HFD3_k127_118624_3 - - - - 0.000000000000000000002411 100.0
HFD3_k127_1188741_0 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 331.0
HFD3_k127_1188741_1 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 310.0
HFD3_k127_1188741_2 Protein of unknown function DUF116 K09729 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001227 265.0
HFD3_k127_1188741_3 Tetratricopeptide repeats - - - 0.00000000000000000000000000000000000000000000000000000005491 224.0
HFD3_k127_1188741_4 Polypeptide deformylase K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000005013 184.0
HFD3_k127_1189764_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621,K21576,K21577 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.21.4.2,1.21.4.3,1.21.4.4,2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 353.0
HFD3_k127_1189764_1 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 310.0
HFD3_k127_1189764_2 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000000001152 123.0
HFD3_k127_1189764_3 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000005537 81.0
HFD3_k127_1196544_0 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 6.165e-242 764.0
HFD3_k127_1196544_1 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 432.0
HFD3_k127_1196544_2 Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 376.0
HFD3_k127_1196544_3 Methylenetetrahydrofolate reductase K00297 GO:0003674,GO:0003824,GO:0004489,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 329.0
HFD3_k127_1196544_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 - 2.1.1.246,4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 335.0
HFD3_k127_1196544_5 Methionine synthase, cobalamin (vitamin B12)-binding module, cap - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 311.0
HFD3_k127_1196544_6 TIGRFAM iron-sulfur cluster binding protein - - - 0.0000000000000000000000000000000000000000000007762 173.0
HFD3_k127_1196544_7 PFAM Carboxymuconolactone decarboxylase - - - 0.00000000000000000000000000000000000000002192 157.0
HFD3_k127_1196544_8 - - - - 0.000000000000000007392 88.0
HFD3_k127_1196544_9 phosphorelay signal transduction system K07714 - - 0.00004835 51.0
HFD3_k127_1225979_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 2.435e-198 633.0
HFD3_k127_1225979_1 General secretion pathway protein F K02455,K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003956 364.0
HFD3_k127_1225979_2 general secretion pathway protein G K02456 - - 0.0000000000000000000000000000000000000000000000000002929 188.0
HFD3_k127_1225979_3 Type II secretion system (T2SS), protein M K02462 - - 0.00000000000000002591 88.0
HFD3_k127_1225979_4 Type IV pilus assembly protein PilM; K02461 - - 0.000000000008228 78.0
HFD3_k127_1225979_5 protein transport across the cell outer membrane K02246,K02457,K02459,K02672,K08084 - - 0.0000000001148 70.0
HFD3_k127_1225979_6 Type II secretion system (T2SS), protein J K02459 - - 0.0000000002552 70.0
HFD3_k127_1225979_7 Prokaryotic N-terminal methylation motif - - - 0.000000001545 65.0
HFD3_k127_1225979_8 PFAM General secretion pathway protein K K02460 - - 0.000000009025 66.0
HFD3_k127_123520_0 Actin K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004316 259.0
HFD3_k127_123520_1 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000000000000005874 190.0
HFD3_k127_123520_2 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000006277 178.0
HFD3_k127_123520_3 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000003096 132.0
HFD3_k127_123520_4 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000002164 117.0
HFD3_k127_123520_5 phospholipase K01058 - 3.1.1.32,3.1.1.4 0.0000000000000000001688 100.0
HFD3_k127_123520_6 light absorption - - - 0.00000000000009479 77.0
HFD3_k127_123520_7 Protein required for attachment to host cells - - - 0.000000000004938 72.0
HFD3_k127_123520_8 - - - - 0.000001265 51.0
HFD3_k127_1349890_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 5.731e-205 650.0
HFD3_k127_1349890_1 molybdopterin oxidoreductase Fe4S4 region K05299 - 1.17.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 451.0
HFD3_k127_1349890_2 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 407.0
HFD3_k127_1349890_3 cyclic nucleotide-binding - - - 0.0000000000000000000000000002308 119.0
HFD3_k127_1387974_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000681 488.0
HFD3_k127_1387974_1 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 367.0
HFD3_k127_1387974_10 Domain of unknown function (DUF296) - - - 0.000000000000000000000000000000000000001092 151.0
HFD3_k127_1387974_11 Transcriptional regulator, MerR family - - - 0.000000000000000000000001353 117.0
HFD3_k127_1387974_2 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 334.0
HFD3_k127_1387974_3 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.0000000000000000000000000000000000000000000000000000000002869 211.0
HFD3_k127_1387974_4 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000008239 203.0
HFD3_k127_1387974_5 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.000000000000000000000000000000000000000000000000000001599 199.0
HFD3_k127_1387974_6 MoaE protein K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000624 188.0
HFD3_k127_1387974_7 Poly A polymerase head domain K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000002213 169.0
HFD3_k127_1387974_8 metalloendopeptidase activity K03799 - - 0.0000000000000000000000000000000000000000002442 178.0
HFD3_k127_1387974_9 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000000000000000000000000008018 159.0
HFD3_k127_14156_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 3.771e-199 629.0
HFD3_k127_14156_1 Transcriptional regulator K11921,K19338 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 331.0
HFD3_k127_14156_2 Poly A polymerase, head domain K00970 - 2.7.7.19 0.000000000000000000000000000001931 130.0
HFD3_k127_14156_3 YbbR-like protein - - - 0.00000009992 56.0
HFD3_k127_146452_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07644 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 423.0
HFD3_k127_146452_1 Transcriptional regulatory protein, C terminal K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005845 322.0
HFD3_k127_1475056_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 541.0
HFD3_k127_1475056_1 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 460.0
HFD3_k127_1475056_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 401.0
HFD3_k127_1475056_3 PFAM peptidase M48 Ste24p K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000001337 236.0
HFD3_k127_1475056_4 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000000000000000006771 176.0
HFD3_k127_1475056_5 Stage II sporulation protein E (SpoIIE) - - - 0.0000000000000000000706 96.0
HFD3_k127_152038_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 2.965e-256 802.0
HFD3_k127_152038_1 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003991 268.0
HFD3_k127_152038_2 COG1192 ATPases involved in chromosome partitioning K03496 GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007 - 0.000000000000000000000000000000000000000000000000000000000002488 211.0
HFD3_k127_152038_3 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000001823 119.0
HFD3_k127_1555451_0 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K15738 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010528,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031323,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0070894,GO:0071944,GO:0080090,GO:0097159,GO:1901363 - 4.561e-239 754.0
HFD3_k127_1555451_2 SMART Rhodanese domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003912 263.0
HFD3_k127_1555451_3 chain release factor K15034 - - 0.000000000000000000000000000000000000000000000000009866 183.0
HFD3_k127_1555451_4 SMART Rhodanese domain protein - - - 0.0000000000000000002361 96.0
HFD3_k127_155645_0 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007595 477.0
HFD3_k127_155645_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003442 280.0
HFD3_k127_155645_2 Protein of unknown function (DUF721) - - - 0.000000000000000000008431 97.0
HFD3_k127_1558514_0 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 479.0
HFD3_k127_1558514_1 GTP-binding protein TypA K06207 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 425.0
HFD3_k127_1558514_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 391.0
HFD3_k127_1558514_3 PFAM Class II aldolase K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 389.0
HFD3_k127_1558514_4 COG0210 Superfamily I DNA and RNA helicases K16898 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 328.0
HFD3_k127_1558514_5 - - - - 0.000000000000000000000000000000000000000000000000311 186.0
HFD3_k127_1558514_7 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.000000002666 59.0
HFD3_k127_1558514_8 UvrD REP helicase K16899 - 3.6.4.12 0.000001603 56.0
HFD3_k127_1577219_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006365 391.0
HFD3_k127_1577219_1 NapC/NirT cytochrome c family, N-terminal region K15876 - - 0.0000000000000000000000000000000000000000000000000000000000002215 214.0
HFD3_k127_1577219_2 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000003172 212.0
HFD3_k127_1604313_0 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000972 528.0
HFD3_k127_1604313_1 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006263 289.0
HFD3_k127_1604313_2 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001273 281.0
HFD3_k127_1604313_3 methyltransferase - - - 0.0000000000000000000000000000000002435 134.0
HFD3_k127_1612302_0 Metalloenzyme superfamily K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 511.0
HFD3_k127_1612302_1 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 341.0
HFD3_k127_1612302_2 ACT domain K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005269 313.0
HFD3_k127_1612302_3 ThiS family K03636 - - 0.0000000000000000000000000000008684 123.0
HFD3_k127_1612302_4 NIL - - - 0.00000000000000000000000002823 110.0
HFD3_k127_1614787_0 PFAM Glycosyl transferase family 2 K03669 - - 1.605e-243 770.0
HFD3_k127_1614787_1 Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) K03670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 515.0
HFD3_k127_1614787_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000006423 199.0
HFD3_k127_1614787_3 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000004042 154.0
HFD3_k127_1614787_4 RibD C-terminal domain - - - 0.00000000000000000000000000000004606 138.0
HFD3_k127_1614787_5 Domain of unknown function (DUF4384) - - - 0.00000006091 59.0
HFD3_k127_1618621_0 glycolate transport K14393 - - 1.826e-232 733.0
HFD3_k127_1618621_1 Protein of unknown function, DUF485 - - - 0.000000000000000000000000000004225 121.0
HFD3_k127_1618621_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000009973 51.0
HFD3_k127_1618621_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0002688 47.0
HFD3_k127_1620277_0 Alpha amylase, catalytic domain K06044 - 5.4.99.15 0.0 1161.0
HFD3_k127_1620277_1 TRAP transporter solute receptor TAXI family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007573 488.0
HFD3_k127_1620277_2 transmembrane signaling receptor activity - - - 0.0000000000000000008479 89.0
HFD3_k127_1648562_0 phosphorelay signal transduction system K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 443.0
HFD3_k127_1648562_1 drug transmembrane transporter activity K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007534 405.0
HFD3_k127_1648562_2 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 343.0
HFD3_k127_1648562_3 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000008044 230.0
HFD3_k127_1648562_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000003389 231.0
HFD3_k127_1648562_5 Methyltransferase domain - - - 0.000000121 62.0
HFD3_k127_1658742_0 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 329.0
HFD3_k127_1658742_1 lactoylglutathione lyase activity - - - 0.0000002968 53.0
HFD3_k127_1667732_0 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 3.144e-194 614.0
HFD3_k127_1667732_1 cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000002333 233.0
HFD3_k127_1667732_2 Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria - - - 0.000000000000000003509 87.0
HFD3_k127_1667847_0 Proton-conducting membrane transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 611.0
HFD3_k127_1667847_1 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 338.0
HFD3_k127_1667847_2 hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000217 239.0
HFD3_k127_1667847_3 PFAM Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 0.00000000000000002493 87.0
HFD3_k127_1667847_4 Proton-conducting membrane transporter - - - 0.000000000002993 67.0
HFD3_k127_1667927_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298 - 1.10.3.10,1.9.3.1 6.943e-245 765.0
HFD3_k127_1667927_1 Glycosyl hydrolase family 57 - - - 2.411e-208 671.0
HFD3_k127_1667927_10 Bacterial Ig-like domain 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 322.0
HFD3_k127_1667927_11 PFAM ATP adenylyltransferase K00988 - 2.7.7.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009009 310.0
HFD3_k127_1667927_12 NOG31153 non supervised orthologous group - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007247 247.0
HFD3_k127_1667927_13 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001588 248.0
HFD3_k127_1667927_14 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000001636 235.0
HFD3_k127_1667927_15 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000001764 177.0
HFD3_k127_1667927_16 nucleotidyltransferase activity K07075 - - 0.000000000000000000000000000000000000000000000002041 180.0
HFD3_k127_1667927_17 - - - - 0.0000000000000000000000000000000000000000000009283 169.0
HFD3_k127_1667927_18 TIGRFAM Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.00000000000000000000000000000001618 134.0
HFD3_k127_1667927_19 GDP-mannose mannosyl hydrolase activity - - - 0.0000000000000000000000003239 107.0
HFD3_k127_1667927_2 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 1.292e-196 629.0
HFD3_k127_1667927_20 Protein of unknown function, DUF393 - - - 0.00000000000000000000002714 104.0
HFD3_k127_1667927_21 radical SAM domain protein - - - 0.0000000000000000000005847 97.0
HFD3_k127_1667927_22 Phosphopantetheine attachment site K02078 - - 0.0000000000000001358 83.0
HFD3_k127_1667927_24 Protein of unknown function (DUF1614) - - - 0.00000003414 64.0
HFD3_k127_1667927_25 cell cycle K05589,K12065,K13052 - - 0.00000003851 60.0
HFD3_k127_1667927_26 Psort location Cytoplasmic, score - - - 0.0000001308 59.0
HFD3_k127_1667927_27 PFAM Tetratricopeptide repeat - - - 0.0000004715 59.0
HFD3_k127_1667927_28 Flavodoxin-like fold - - - 0.000003356 51.0
HFD3_k127_1667927_29 COG1246 N-acetylglutamate synthase and related acetyltransferases - - - 0.0005154 49.0
HFD3_k127_1667927_3 Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities K01782 GO:0003674,GO:0003824,GO:0003857,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0008692,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016856,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 1.1.1.35,4.2.1.17,5.1.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008466 577.0
HFD3_k127_1667927_4 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 504.0
HFD3_k127_1667927_5 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 499.0
HFD3_k127_1667927_6 Beta-ketoacyl synthase, C-terminal domain K09458,K14660 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006912 481.0
HFD3_k127_1667927_7 radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 454.0
HFD3_k127_1667927_8 chalcone and stilbene synthase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 451.0
HFD3_k127_1667927_9 Thiolase, C-terminal domain K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005785 451.0
HFD3_k127_1700585_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1808.0
HFD3_k127_1700585_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1059.0
HFD3_k127_1700585_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000007862 228.0
HFD3_k127_1700585_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000004367 214.0
HFD3_k127_1700585_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000001989 132.0
HFD3_k127_1706281_0 Large family of predicted nucleotide-binding domains K07175 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006357 556.0
HFD3_k127_1706281_1 Family 5 K02035,K15580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 372.0
HFD3_k127_1706281_2 PFAM ResB family protein K07399 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008996 296.0
HFD3_k127_1706281_3 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001388 286.0
HFD3_k127_1706281_4 Peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000000000002129 184.0
HFD3_k127_1706281_5 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000009469 113.0
HFD3_k127_1706281_6 LTXXQ motif family protein - - - 0.00000000000000000000004717 106.0
HFD3_k127_1706281_7 Copper resistance protein CopZ K07213 - - 0.000003205 51.0
HFD3_k127_1708257_0 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000003415 249.0
HFD3_k127_1708257_1 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000004904 202.0
HFD3_k127_1708257_2 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000001059 147.0
HFD3_k127_1726213_0 Orn/Lys/Arg decarboxylase, C-terminal domain K01582,K01585 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008923,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564 4.1.1.18,4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 589.0
HFD3_k127_1726213_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0010487,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0043919,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009191 356.0
HFD3_k127_1726213_2 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.000000000000000000000000000000000000000000000000003656 184.0
HFD3_k127_1726213_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0010487,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0043919,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.00000000000002322 74.0
HFD3_k127_17290_0 phosphate acetyltransferase K00625,K13788 - 2.3.1.8 1.669e-274 860.0
HFD3_k127_17290_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 9.491e-253 788.0
HFD3_k127_17290_2 Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP- dependent clade X sub-subfamily K00850 - 2.7.1.11 1.736e-215 675.0
HFD3_k127_17290_3 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 572.0
HFD3_k127_17290_4 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K14086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 585.0
HFD3_k127_17290_5 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 519.0
HFD3_k127_17290_6 Transcriptional regulator sugar kinase K00886 - 2.7.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000011 281.0
HFD3_k127_17290_7 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K09181,K15520 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0030551,GO:0030552,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.3.1.189 0.0000000000000000000000000000000000000009025 155.0
HFD3_k127_1739566_0 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 3.071e-264 827.0
HFD3_k127_1739566_1 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 609.0
HFD3_k127_1739566_2 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 425.0
HFD3_k127_1739566_3 Pyridoxal-phosphate dependent enzyme K12339,K21148 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113,2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004893 343.0
HFD3_k127_1739566_4 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005201 280.0
HFD3_k127_1739566_5 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000001091 197.0
HFD3_k127_1739566_6 PFAM 4Fe-4S K00196 - - 0.00000000000000000000000000000000000000000000001583 175.0
HFD3_k127_1746368_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.384e-229 720.0
HFD3_k127_1746368_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 535.0
HFD3_k127_1746368_2 ACT domain K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000003746 237.0
HFD3_k127_1746368_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000003418 229.0
HFD3_k127_1746368_4 phosphatidylethanolamine metabolic process K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000004346 220.0
HFD3_k127_1746368_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000006461 70.0
HFD3_k127_1757051_0 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 302.0
HFD3_k127_1757051_1 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000001532 139.0
HFD3_k127_1757051_2 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000006224 112.0
HFD3_k127_1757051_3 signal transduction histidine kinase K02482 - 2.7.13.3 0.000000000000000000000000001525 117.0
HFD3_k127_1757051_5 Belongs to the TPP enzyme family K01637 - 4.1.3.1 0.0000000000003335 81.0
HFD3_k127_1757051_6 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000003688 78.0
HFD3_k127_1757051_7 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.000000628 56.0
HFD3_k127_1757051_8 TM2 domain - - - 0.0003851 45.0
HFD3_k127_180096_0 TonB dependent receptor K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007592 460.0
HFD3_k127_180096_1 radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007053 410.0
HFD3_k127_180096_2 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000004379 200.0
HFD3_k127_180096_3 Diguanylate cyclase K21084 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000005139 209.0
HFD3_k127_180096_4 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000001585 183.0
HFD3_k127_180096_5 GGDEF domain K03413,K07814 - - 0.0000000000000001194 85.0
HFD3_k127_180096_6 peptidase inhibitor activity K01406 - 3.4.24.40 0.0000000000000003033 82.0
HFD3_k127_180096_7 Transcription termination factor nusG - - - 0.0000000103 60.0
HFD3_k127_1805303_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 612.0
HFD3_k127_1805303_1 PFAM IstB domain protein ATP-binding protein K02315 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003895 400.0
HFD3_k127_1805303_2 TIGRFAM primosome, DnaD subunit - - - 0.00000000000000000000000000000003338 134.0
HFD3_k127_1805303_3 Iron permease FTR1 family K07243 - - 0.00000002794 56.0
HFD3_k127_181034_0 tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 303.0
HFD3_k127_181034_1 General secretory system II protein E domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000005869 244.0
HFD3_k127_181034_2 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000000000000000000000000000000000000000000007481 223.0
HFD3_k127_181034_3 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.00000000000000000000000000000000000000000000000000000000002396 211.0
HFD3_k127_181034_4 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000009659 159.0
HFD3_k127_181034_5 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000449 143.0
HFD3_k127_181034_6 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000001141 121.0
HFD3_k127_181034_7 phosphohistidine phosphatase, SixA K03574,K08296 - 3.6.1.55 0.00000000000000000000000009327 113.0
HFD3_k127_181034_8 Ferredoxin K05337 - - 0.00000000000000000002021 93.0
HFD3_k127_1817589_0 aspartate-tRNA(Asn) ligase activity K01876 - 6.1.1.12 1.72e-249 782.0
HFD3_k127_1817589_1 response to heat K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008492 398.0
HFD3_k127_1817589_2 acyl-CoA dehydrogenase activity K06446 - - 0.0000000000000000000000000000000001008 155.0
HFD3_k127_1817589_3 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.0000000000000003678 94.0
HFD3_k127_1817589_4 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000002578 66.0
HFD3_k127_1840708_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008926 604.0
HFD3_k127_1840708_1 AIR synthase related protein domain protein K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 465.0
HFD3_k127_1840708_10 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000001872 257.0
HFD3_k127_1840708_11 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000004751 275.0
HFD3_k127_1840708_12 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000002598 218.0
HFD3_k127_1840708_13 Peptidase family M50 - - - 0.0000000000000000000000000000000000001372 148.0
HFD3_k127_1840708_14 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000006016 118.0
HFD3_k127_1840708_15 - - - - 0.00000000000000000000000001158 116.0
HFD3_k127_1840708_16 - - - - 0.00000000001457 71.0
HFD3_k127_1840708_2 electron transfer flavoprotein, alpha subunit K03522,K22432 - 1.3.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 464.0
HFD3_k127_1840708_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K14986 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 462.0
HFD3_k127_1840708_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 357.0
HFD3_k127_1840708_5 malonyl coa-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 347.0
HFD3_k127_1840708_6 electron transfer activity K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000075 334.0
HFD3_k127_1840708_7 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 315.0
HFD3_k127_1840708_8 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004682 311.0
HFD3_k127_1840708_9 Periplasmic binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009347 289.0
HFD3_k127_1851193_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007132 306.0
HFD3_k127_1851193_1 Cysteine-rich domain K08264 - 1.8.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003216 308.0
HFD3_k127_1851193_2 - - - - 0.000000000000000007957 85.0
HFD3_k127_1851193_3 Nitrate reductase gamma subunit - - - 0.000000002043 68.0
HFD3_k127_1851193_4 Universal stress protein - - - 0.00000001503 63.0
HFD3_k127_1854390_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K13378 - 1.6.5.3 1.378e-299 927.0
HFD3_k127_1854390_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 340.0
HFD3_k127_1854390_2 Acyl-transferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 313.0
HFD3_k127_1854390_3 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007797 276.0
HFD3_k127_1854390_4 NADH ubiquinone oxidoreductase 24 kD subunit K00334 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0050136,GO:0051536,GO:0051537,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000002093 206.0
HFD3_k127_1854390_5 PFAM glycoside hydrolase, family 3 domain protein K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000001912 193.0
HFD3_k127_1854390_6 NADH dehydrogenase (ubiquinone) activity K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.00000000000000000000000000000000000000000025 161.0
HFD3_k127_1854390_7 Aminoacyl-tRNA editing domain K19055 - - 0.0000000000000000000000000000000000000008819 153.0
HFD3_k127_1854390_8 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 0.000000000000009124 75.0
HFD3_k127_1878572_0 phosphorelay sensor kinase activity K03320,K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000609 407.0
HFD3_k127_1878572_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000293 271.0
HFD3_k127_1878572_2 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000000000000000001894 140.0
HFD3_k127_1878572_3 TIGRFAM competence damage-inducible protein CinA K03742,K03743 - 3.5.1.42 0.0000000001249 63.0
HFD3_k127_1889114_0 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 525.0
HFD3_k127_1889114_1 3-beta hydroxysteroid dehydrogenase/isomerase family K10011,K12449 - 1.1.1.305,2.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 477.0
HFD3_k127_1889114_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 461.0
HFD3_k127_1889114_3 Glycosyl transferase family 2 K10012,K20534 - 2.4.2.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 401.0
HFD3_k127_1889114_4 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005527 393.0
HFD3_k127_1889114_5 Small Multidrug Resistance protein - - - 0.0000000000000000000000000000000000002542 145.0
HFD3_k127_1903877_0 PFAM Type II secretion system protein E K02283,K03609 - - 2.162e-199 630.0
HFD3_k127_1903877_1 Belongs to the GSP D family K02280 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 482.0
HFD3_k127_1903877_10 protocatechuate 3,4-dioxygenase - - - 0.000000000000000000000000000000000000000000000001994 181.0
HFD3_k127_1903877_11 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000000000000000000000000001044 140.0
HFD3_k127_1903877_12 PFAM TadE family protein - - - 0.00000000000000000000000000000007025 129.0
HFD3_k127_1903877_13 ribonucleoside-diphosphate reductase activity K07735 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000001119 134.0
HFD3_k127_1903877_14 PFAM Cold-shock K03704 - - 0.0000000000000000000000003277 105.0
HFD3_k127_1903877_15 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000002741 96.0
HFD3_k127_1903877_16 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000001408 90.0
HFD3_k127_1903877_17 Cytochrome c7 and related cytochrome c - - - 0.000000000000000009357 86.0
HFD3_k127_1903877_19 Pentapeptide repeats (9 copies) - - - 0.0000000003381 69.0
HFD3_k127_1903877_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 370.0
HFD3_k127_1903877_20 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000001187 57.0
HFD3_k127_1903877_3 type II secretion system protein K12510 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005445 283.0
HFD3_k127_1903877_4 Flp pilus assembly protein, ATPase CpaE K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001394 271.0
HFD3_k127_1903877_5 PFAM type II secretion system K12511 - - 0.000000000000000000000000000000000000000000000000000000000000000000005415 249.0
HFD3_k127_1903877_6 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000007948 247.0
HFD3_k127_1903877_7 PFAM flavin reductase domain protein FMN-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000001543 226.0
HFD3_k127_1903877_8 Flp pilus assembly protein CpaB K02279 - - 0.000000000000000000000000000000000000000000000000000000000000001043 229.0
HFD3_k127_1903877_9 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.00000000000000000000000000000000000000000000000000001815 197.0
HFD3_k127_1977675_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009012 368.0
HFD3_k127_1977675_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 356.0
HFD3_k127_1977675_2 transglycosylase K08309 - - 0.000000000000000000000000000000000000003168 154.0
HFD3_k127_1977675_3 Transport permease protein K09694 - - 0.000000000000006484 77.0
HFD3_k127_1994681_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 3.602e-253 802.0
HFD3_k127_1994681_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 595.0
HFD3_k127_1994681_10 Belongs to the 'phage' integrase family - - - 0.000006727 48.0
HFD3_k127_1994681_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 457.0
HFD3_k127_1994681_3 Serine Threonine protein kinase K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 411.0
HFD3_k127_1994681_4 TIGRFAM MazG family protein K02428,K02499 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 296.0
HFD3_k127_1994681_5 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000000000000000000000000003155 216.0
HFD3_k127_1994681_6 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000001999 165.0
HFD3_k127_1994681_7 - - - - 0.000000001763 64.0
HFD3_k127_1994681_8 TIGRFAM electron transport complex, RnfABCDGE type, B subunit K03616 - - 0.00000003595 56.0
HFD3_k127_1994681_9 Phage integrase family - - - 0.0000003306 54.0
HFD3_k127_1997304_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 426.0
HFD3_k127_1997304_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000577 388.0
HFD3_k127_1997304_2 PFAM NIF3 (NGG1p interacting factor 3) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 322.0
HFD3_k127_1997304_3 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000006385 196.0
HFD3_k127_1997304_4 Ribosomal protein S9/S16 K02996 - - 0.0000000000000000000000000000000000000000000000002121 179.0
HFD3_k127_1997304_5 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000003488 148.0
HFD3_k127_1997304_6 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000003361 83.0
HFD3_k127_203318_0 DnaJ central domain K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003392 466.0
HFD3_k127_203318_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 337.0
HFD3_k127_203318_2 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001777 235.0
HFD3_k127_2074_0 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005197 553.0
HFD3_k127_2074_1 Ecdysteroid kinase K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 463.0
HFD3_k127_2074_2 Glutamine amidotransferase class-I - - - 0.0000000000000000000000000000000000000000000000813 172.0
HFD3_k127_2074_3 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000006819 134.0
HFD3_k127_2074_4 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.0000000000000000000000000001187 134.0
HFD3_k127_2074_5 - - - - 0.000000000000159 74.0
HFD3_k127_2074_6 PFAM Fibronectin, type III domain - - - 0.000003554 61.0
HFD3_k127_2135807_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1293.0
HFD3_k127_2135807_1 Aldo/keto reductase family K00002 - 1.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 342.0
HFD3_k127_2135807_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001616 261.0
HFD3_k127_2151792_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007285 439.0
HFD3_k127_2151792_1 lipopolysaccharide transport protein B ATP-binding component of ABC superfamily K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 320.0
HFD3_k127_2151792_2 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000000000000000000000429 157.0
HFD3_k127_2151792_3 OstA-like protein K09774 - - 0.000000000000000000000003781 108.0
HFD3_k127_2151792_4 ATP-binding region, ATPase domain protein - - - 0.00000000000000005619 92.0
HFD3_k127_2151792_5 Histidine Phosphotransfer domain - - - 0.000000005429 67.0
HFD3_k127_2151792_6 Lipopolysaccharide-assembly, LptC-related - - - 0.0000004134 59.0
HFD3_k127_2151792_7 Transposase IS200 like K07491 - - 0.00001077 47.0
HFD3_k127_215307_0 GTP-binding protein TypA K06207 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 344.0
HFD3_k127_215307_1 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 344.0
HFD3_k127_215307_2 DUF218 domain - - - 0.00000000000000004175 84.0
HFD3_k127_222604_0 Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate K15527 - 2.5.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000077 349.0
HFD3_k127_222604_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K13039 - 4.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 339.0
HFD3_k127_222604_2 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008825 318.0
HFD3_k127_222604_3 peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000281 190.0
HFD3_k127_222604_4 PFAM Nitrate reductase gamma subunit - - - 0.000000000000000000001424 104.0
HFD3_k127_2302007_0 Mo-co oxidoreductase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003867 434.0
HFD3_k127_2302007_1 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009343 397.0
HFD3_k127_2302007_2 Cytochrome C oxidase, cbb3-type, subunit III K08906 - - 0.000000000000000000000000005588 113.0
HFD3_k127_2302007_3 Cytochrome c - - - 0.0000000000001209 78.0
HFD3_k127_2302007_4 EamA-like transporter family - - - 0.0000000000007279 76.0
HFD3_k127_23029_1 helix_turn_helix, Lux Regulon K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000000001003 237.0
HFD3_k127_23029_2 Histidine kinase K07675 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000001616 234.0
HFD3_k127_23029_3 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.000000000000000000000000000000000002822 144.0
HFD3_k127_23029_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000001301 137.0
HFD3_k127_23029_5 PFAM YeeE YedE family (DUF395) K07112 - - 0.000000001796 62.0
HFD3_k127_23029_6 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.00002938 53.0
HFD3_k127_23029_7 - - - - 0.00006777 50.0
HFD3_k127_2340467_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 515.0
HFD3_k127_2340467_1 Domain of unknown function DUF11 - - - 0.0000000000000000000000205 114.0
HFD3_k127_2340467_2 COG0330 Membrane protease subunits, stomatin prohibitin homologs - - - 0.0004509 46.0
HFD3_k127_2376108_0 4Fe-4S dicluster domain - - - 2.536e-302 932.0
HFD3_k127_2376108_1 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 520.0
HFD3_k127_2376108_10 DsrE/DsrF-like family K07236 - - 0.00003641 51.0
HFD3_k127_2376108_2 PFAM Nitrate reductase gamma subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003949 456.0
HFD3_k127_2376108_3 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004064 339.0
HFD3_k127_2376108_4 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 330.0
HFD3_k127_2376108_5 TIGRFAM Tat (twin-arginine translocation) pathway signal sequence K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005714 327.0
HFD3_k127_2376108_6 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.000000000000000000000000000000000000000000000001893 179.0
HFD3_k127_2376108_7 - - - - 0.0000000000000000000000000000000000000000000007734 169.0
HFD3_k127_2376108_8 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000077 87.0
HFD3_k127_2376108_9 DsrE/DsrF-like family K07235 - - 0.00000000000306 72.0
HFD3_k127_2379772_0 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 419.0
HFD3_k127_2379772_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000004752 157.0
HFD3_k127_2379772_2 Protein of unknown function, DUF485 - - - 0.0008282 42.0
HFD3_k127_2381677_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 1.409e-253 795.0
HFD3_k127_2381677_1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 2.179e-247 778.0
HFD3_k127_2381677_2 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 1.917e-196 624.0
HFD3_k127_2381677_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 471.0
HFD3_k127_2381677_4 Belongs to the complex I subunit 6 family K00339 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000002161 217.0
HFD3_k127_2381677_5 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000118 166.0
HFD3_k127_2381677_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000000000000000001284 152.0
HFD3_k127_2381677_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000001679 117.0
HFD3_k127_2382856_0 Multicopper oxidase K06324 - 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 521.0
HFD3_k127_2382856_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 416.0
HFD3_k127_2382856_2 MarC family integral membrane protein K05595 - - 0.0005692 43.0
HFD3_k127_238604_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 8.292e-236 742.0
HFD3_k127_238604_1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 2.231e-211 675.0
HFD3_k127_238604_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008748 576.0
HFD3_k127_238604_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 451.0
HFD3_k127_238604_4 PDZ domain (Also known as DHR or GLGF) K08372 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 420.0
HFD3_k127_238604_5 FMN binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007107 402.0
HFD3_k127_238604_6 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002969 403.0
HFD3_k127_238604_7 Lytic transglycosylase, SLT, LysM and LysM domain-containing K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003391 268.0
HFD3_k127_238604_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000004582 85.0
HFD3_k127_238604_9 YwiC-like protein - - - 0.00001431 55.0
HFD3_k127_2409834_0 phosphorelay signal transduction system K02535,K13599,K16363 - 3.5.1.108,4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007575 327.0
HFD3_k127_2409834_1 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000002829 219.0
HFD3_k127_2409834_2 PFAM NHL repeat containing protein - - - 0.00000002235 66.0
HFD3_k127_2415542_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004852 509.0
HFD3_k127_2415542_1 Bacterial extracellular solute-binding protein K02027,K10236 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 432.0
HFD3_k127_2415542_10 - - - - 0.000000000000008256 79.0
HFD3_k127_2415542_12 - - - - 0.0000008969 51.0
HFD3_k127_2415542_2 PFAM ABC transporter related K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 341.0
HFD3_k127_2415542_3 Binding-protein-dependent transport system inner membrane component K02025,K10237,K15771 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 336.0
HFD3_k127_2415542_4 Binding-protein-dependent transport system inner membrane component K02026,K10238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000054 330.0
HFD3_k127_2415542_5 HflC protein - - - 0.00000000000000000000000000000000000000000000000000000000000001227 226.0
HFD3_k127_2415542_6 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000001297 154.0
HFD3_k127_2415542_7 - - - - 0.0000000000000000000000000000000000001531 147.0
HFD3_k127_2415542_8 Glutaredoxin - - - 0.00000000000000000000000000001548 121.0
HFD3_k127_2415542_9 PFAM Rhodanese domain protein - - - 0.0000000000000000000004263 100.0
HFD3_k127_241637_0 Bacterial regulatory protein, Fis family K07715 - - 3.283e-208 655.0
HFD3_k127_241637_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000995 452.0
HFD3_k127_2447911_0 Surface antigen K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006607 572.0
HFD3_k127_2447911_1 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 493.0
HFD3_k127_2447911_2 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes K06132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 437.0
HFD3_k127_2447911_3 Domain of unknown function (DUF374) K09778 - - 0.00000000000000000000000000000000000705 145.0
HFD3_k127_2447911_4 Domain of unknown function (DUF4136) - - - 0.00000000000000000003256 97.0
HFD3_k127_2447911_5 response to heat K03668 - - 0.00000000000000009911 87.0
HFD3_k127_2450478_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000001875 261.0
HFD3_k127_2450478_1 domain protein - - - 0.000000000000000000000000000000000001835 160.0
HFD3_k127_2450478_2 PFAM Fibronectin type III domain - - - 0.0001351 55.0
HFD3_k127_245372_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1010.0
HFD3_k127_245372_1 Endopeptidase La K04076 - 3.4.21.53 2.371e-234 750.0
HFD3_k127_245372_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009793 314.0
HFD3_k127_245372_11 Cytidine and deoxycytidylate deaminase zinc-binding region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002713 254.0
HFD3_k127_245372_12 - - - - 0.000000000000000000000006148 103.0
HFD3_k127_245372_2 Bacterial protein of unknown function (DUF853) K06915 - - 2.487e-219 690.0
HFD3_k127_245372_3 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 4.495e-209 659.0
HFD3_k127_245372_4 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 629.0
HFD3_k127_245372_5 Transketolase K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007972 520.0
HFD3_k127_245372_6 Belongs to the RuBisCO large chain family K01601 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007967 499.0
HFD3_k127_245372_7 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 440.0
HFD3_k127_245372_8 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441 377.0
HFD3_k127_245372_9 PFAM MltA K08304 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 351.0
HFD3_k127_2465962_0 Protein of unknown function, DUF255 K06888 - - 2.356e-245 775.0
HFD3_k127_2465962_1 DJ-1/PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000000004073 253.0
HFD3_k127_2465962_3 Involved in the TonB-independent uptake of proteins K03641 - - 0.0000000000002344 70.0
HFD3_k127_2485417_0 carbon starvation protein CstA K06200 - - 1.067e-319 987.0
HFD3_k127_2485417_1 Molybdopterin oxidoreductase Fe4S4 domain - - - 6.313e-286 887.0
HFD3_k127_2485417_10 - - - - 0.0000000000000000000000000103 113.0
HFD3_k127_2485417_11 Protein of unknown function (DUF3187) - - - 0.00000000000000000000008451 110.0
HFD3_k127_2485417_12 Predicted RNA-binding protein - - - 0.00001643 49.0
HFD3_k127_2485417_2 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007314 471.0
HFD3_k127_2485417_3 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005279 367.0
HFD3_k127_2485417_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 354.0
HFD3_k127_2485417_5 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 338.0
HFD3_k127_2485417_6 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 288.0
HFD3_k127_2485417_7 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000000000003701 193.0
HFD3_k127_2485417_8 GYD domain - - - 0.000000000000000000000000000000000000006386 148.0
HFD3_k127_2485417_9 Outer membrane lipoprotein Slp family K07285 - - 0.0000000000000000000000000009526 121.0
HFD3_k127_2489072_0 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 348.0
HFD3_k127_2489072_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005974 346.0
HFD3_k127_2489072_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 294.0
HFD3_k127_2489072_3 HEAT repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008456 294.0
HFD3_k127_2489072_4 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000274 300.0
HFD3_k127_2489072_5 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004333 282.0
HFD3_k127_2489072_6 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000792 139.0
HFD3_k127_2489072_7 TIGRFAM phosphonate ABC transporter, periplasmic phosphonate-binding protein K02044 - - 0.0000000000000000000000000000000001826 154.0
HFD3_k127_2547148_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1379.0
HFD3_k127_2547148_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005841 347.0
HFD3_k127_2547148_2 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000002516 236.0
HFD3_k127_2547148_3 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000008204 154.0
HFD3_k127_2547148_4 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000004447 130.0
HFD3_k127_2547148_5 Outer membrane lipoprotein - - - 0.000000000000000000000000001281 123.0
HFD3_k127_2547148_6 - - - - 0.000000000000000000008563 94.0
HFD3_k127_2547148_7 Histidine Phosphotransfer domain - - - 0.0000000001675 64.0
HFD3_k127_25734_0 Seven times multi-haem cytochrome CxxCH - - - 2.789e-195 617.0
HFD3_k127_25734_1 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000006306 224.0
HFD3_k127_25734_2 Putative methyltransferase - - - 0.000000000000000000000003972 114.0
HFD3_k127_2585187_0 NADP-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 483.0
HFD3_k127_2585187_1 Methyltransferase domain - - - 0.0000000000000000000000004654 113.0
HFD3_k127_2620901_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006321 502.0
HFD3_k127_2620901_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 349.0
HFD3_k127_2620901_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000007572 224.0
HFD3_k127_2620901_3 Preprotein translocase subunit K03210 - - 0.00000000000000000000000000002944 120.0
HFD3_k127_2620901_4 Transglycosylase SLT domain K07114,K08309 - - 0.0000000000000000000000001023 123.0
HFD3_k127_2620901_5 metal cluster binding K06940 - - 0.000000000005194 74.0
HFD3_k127_269587_0 SMART Elongator protein 3 MiaB NifB - - - 1.167e-207 657.0
HFD3_k127_269587_1 Sulphur transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 451.0
HFD3_k127_269587_10 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008478 248.0
HFD3_k127_269587_11 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000001198 192.0
HFD3_k127_269587_12 PFAM YeeE YedE family (DUF395) K07112 - - 0.000000000000000000000000000000000000000000000000002088 198.0
HFD3_k127_269587_13 signal transduction histidine kinase K10125 - 2.7.13.3 0.0000000000000000000000000000000000000000000003473 186.0
HFD3_k127_269587_14 Predicted membrane protein (DUF2318) - - - 0.000000000000000000000000000689 121.0
HFD3_k127_269587_15 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000000000003212 109.0
HFD3_k127_269587_16 regulation of response to stimulus K13730 - - 0.000000000000001844 90.0
HFD3_k127_269587_17 Universal stress protein - - - 0.000000000001207 75.0
HFD3_k127_269587_19 PFAM UspA domain protein - - - 0.00000000005471 70.0
HFD3_k127_269587_2 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 420.0
HFD3_k127_269587_21 sulfur carrier activity - GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.000000004152 61.0
HFD3_k127_269587_22 Universal stress protein family - - - 0.000000006148 63.0
HFD3_k127_269587_23 - - - - 0.00000001284 57.0
HFD3_k127_269587_25 hydrolase family 81 - - - 0.00004528 56.0
HFD3_k127_269587_26 peptidylprolyl isomerase K03771 - 5.2.1.8 0.0001151 53.0
HFD3_k127_269587_27 Universal stress protein - - - 0.0002382 50.0
HFD3_k127_269587_28 - - - - 0.0004742 44.0
HFD3_k127_269587_3 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005549 421.0
HFD3_k127_269587_4 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003981 379.0
HFD3_k127_269587_5 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 364.0
HFD3_k127_269587_6 Protoporphyrinogen oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 350.0
HFD3_k127_269587_8 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 338.0
HFD3_k127_269587_9 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002136 247.0
HFD3_k127_2706598_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 4.838e-278 877.0
HFD3_k127_2706598_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003454 293.0
HFD3_k127_2706598_2 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000004868 126.0
HFD3_k127_2706598_3 Tetratricopeptide repeat - - - 0.000000000000000000003856 103.0
HFD3_k127_2706598_4 Domain of unknown function (DUF4115) - - - 0.000000000000000000004706 104.0
HFD3_k127_2724134_0 Bacterial regulatory helix-turn-helix proteins, AraC family K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 308.0
HFD3_k127_2724134_1 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001163 276.0
HFD3_k127_2730097_0 Belongs to the glutamate synthase family K00265 - 1.4.1.13,1.4.1.14 2.898e-297 917.0
HFD3_k127_2730097_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 1.226e-267 837.0
HFD3_k127_2730097_2 glutamate synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 394.0
HFD3_k127_2730097_3 FMN binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 345.0
HFD3_k127_2814282_0 PFAM Acetyl-CoA hydrolase transferase K18122 - - 1.33e-288 896.0
HFD3_k127_2814282_1 ATP-grasp domain K01905,K22224 - 6.2.1.13 1.631e-254 802.0
HFD3_k127_2814282_2 belongs to the CobB CobQ family K06873 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006126 266.0
HFD3_k127_2814282_3 23S rRNA-intervening sequence protein - - - 0.0002127 46.0
HFD3_k127_2843234_0 Phosphoglycerate kinase K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007421 564.0
HFD3_k127_2843234_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000946 488.0
HFD3_k127_2843234_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000005026 147.0
HFD3_k127_2843234_3 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000007799 134.0
HFD3_k127_2862782_0 Putative MetA-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003196 272.0
HFD3_k127_2862782_1 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000001296 154.0
HFD3_k127_2862782_2 PFAM FeoA family protein K04758 - - 0.00000000000000000000000000000004523 126.0
HFD3_k127_2862782_3 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.0000000000000000000000001195 108.0
HFD3_k127_2862782_4 iron ion homeostasis K04758 - - 0.000000000000000009738 87.0
HFD3_k127_2875035_0 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006543 284.0
HFD3_k127_2875035_1 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001468 265.0
HFD3_k127_2875035_10 Membrane - - - 0.000000000001294 68.0
HFD3_k127_2875035_11 AAA ATPase, central domain protein - - - 0.000000000004231 69.0
HFD3_k127_2875035_2 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000007759 207.0
HFD3_k127_2875035_3 PLD-like domain K06131 - - 0.00000000000000000000000000000000000000000000002053 175.0
HFD3_k127_2875035_4 Membrane - - - 0.000000000000000000000000000000000000000000008376 168.0
HFD3_k127_2875035_5 - - - - 0.000000000000000000000000000000000003391 148.0
HFD3_k127_2875035_6 Transposase - - - 0.0000000000000000000000000000005565 125.0
HFD3_k127_2875035_7 PLD-like domain K06131 - - 0.00000000000002172 72.0
HFD3_k127_2875035_8 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000006437 78.0
HFD3_k127_2875035_9 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000001547 70.0
HFD3_k127_2906977_0 Neisseria PilC beta-propeller domain K02674 - - 1.203e-205 700.0
HFD3_k127_2906977_1 Prokaryotic N-terminal methylation motif - - - 0.00000000000000000000000000000000000000000000000000000000000002134 227.0
HFD3_k127_2906977_2 PKD domain containing protein K01337,K20276,K21449 - 3.4.21.50 0.0000000000000000000000000000004011 144.0
HFD3_k127_2906977_3 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000001784 91.0
HFD3_k127_2906977_4 Prokaryotic N-terminal methylation motif - - - 0.000001276 57.0
HFD3_k127_3017_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000004086 231.0
HFD3_k127_3017_1 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000004655 241.0
HFD3_k127_3017_2 protein phosphatase 2C domain protein K01090,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000001656 211.0
HFD3_k127_3017_3 YtxH-like protein - - - 0.000000000001018 71.0
HFD3_k127_3017_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000004334 75.0
HFD3_k127_3017_5 Transposase K07496 - - 0.000000005044 58.0
HFD3_k127_3061604_0 Phosphoenolpyruvate carboxykinase K01610 - 4.1.1.49 1.56e-254 794.0
HFD3_k127_3061604_1 DNA polymerase K02347 - - 3.661e-217 692.0
HFD3_k127_3061604_10 Zinc dependent phospholipase C - - - 0.00000000000000000000000000000000000000000001783 167.0
HFD3_k127_3061604_11 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240,K00245 - 1.3.5.1,1.3.5.4 0.0000000000000000001217 89.0
HFD3_k127_3061604_12 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000749 93.0
HFD3_k127_3061604_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009705 538.0
HFD3_k127_3061604_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007127 482.0
HFD3_k127_3061604_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008999 423.0
HFD3_k127_3061604_5 pfam abc K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 361.0
HFD3_k127_3061604_6 ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006297 313.0
HFD3_k127_3061604_7 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001047 259.0
HFD3_k127_3061604_8 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002217 256.0
HFD3_k127_3061604_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004179 253.0
HFD3_k127_309902_0 Sigma-54 interaction domain K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006852 447.0
HFD3_k127_309902_1 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 439.0
HFD3_k127_309902_2 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006287 406.0
HFD3_k127_309902_3 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005507 386.0
HFD3_k127_309902_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000001006 207.0
HFD3_k127_309902_5 Mitochondrial small ribosomal subunit Rsm22 - - - 0.000000000000000000000000000000000000000000000000000001159 205.0
HFD3_k127_309902_6 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.0000000000000000000000000000000000000000000000000000016 196.0
HFD3_k127_309902_7 Domain of unknown function (DUF3786) - - - 0.0000000000000000000000000000000000000000002892 165.0
HFD3_k127_3108409_0 Putative ATP-binding cassette K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 410.0
HFD3_k127_3108409_1 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005028 252.0
HFD3_k127_3108409_2 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002648 251.0
HFD3_k127_311667_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 6.156e-267 852.0
HFD3_k127_311667_1 PFAM Alcohol dehydrogenase K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 491.0
HFD3_k127_311667_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 405.0
HFD3_k127_311667_3 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 390.0
HFD3_k127_311667_4 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000006897 269.0
HFD3_k127_311667_5 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070041,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000063 269.0
HFD3_k127_311667_6 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000006448 138.0
HFD3_k127_311732_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 1.945e-274 873.0
HFD3_k127_311732_1 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.00000000000000000000000000005728 121.0
HFD3_k127_311732_2 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00009527 48.0
HFD3_k127_3130743_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003497 252.0
HFD3_k127_3130743_1 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000002119 187.0
HFD3_k127_3130743_2 Thioredoxin-like - - - 0.000000000000000000000000000000000000000002087 161.0
HFD3_k127_3136106_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 5.515e-253 806.0
HFD3_k127_3136106_1 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 617.0
HFD3_k127_3136106_2 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005573 478.0
HFD3_k127_3136106_3 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000002296 240.0
HFD3_k127_3136106_4 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000011 228.0
HFD3_k127_3136106_5 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.0000000000000000000000000000000000000000000000001156 183.0
HFD3_k127_3136106_6 - - - - 0.00000000000000002848 87.0
HFD3_k127_3139387_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 493.0
HFD3_k127_3139387_1 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 370.0
HFD3_k127_3139387_2 ferredoxin-thioredoxin reductase activity - - - 0.000000000000000000000000000000000000000004061 157.0
HFD3_k127_3139387_3 Outer membrane lipoprotein Slp family K07285 - - 0.000000000000000000000000000000000000009872 151.0
HFD3_k127_3139387_4 PFAM Glutaredoxin K06191 - - 0.0000000000000000000001213 99.0
HFD3_k127_3140973_0 PFAM FAD linked oxidase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009019 475.0
HFD3_k127_3140973_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 359.0
HFD3_k127_3140973_2 - - - - 0.000001265 51.0
HFD3_k127_3149839_0 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000005169 235.0
HFD3_k127_3149839_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000004774 178.0
HFD3_k127_3149839_2 PAS fold - - - 0.00000000004577 64.0
HFD3_k127_3157770_0 FAD binding domain K00394 - 1.8.99.2 0.0 1073.0
HFD3_k127_3157770_1 Methyl-viologen-reducing hydrogenase, delta subunit K03388,K16885,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1e-323 1006.0
HFD3_k127_3157770_10 COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006994 411.0
HFD3_k127_3157770_11 Cys Met metabolism K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 382.0
HFD3_k127_3157770_12 nitrate reductase activity K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 370.0
HFD3_k127_3157770_13 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 328.0
HFD3_k127_3157770_14 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 294.0
HFD3_k127_3157770_15 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000811 247.0
HFD3_k127_3157770_16 LysM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001524 240.0
HFD3_k127_3157770_17 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000004427 237.0
HFD3_k127_3157770_18 mRNA catabolic process - - - 0.0000000000000000000000000000000000000000000000001008 186.0
HFD3_k127_3157770_19 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.000000000000000000000000000000000000000001003 162.0
HFD3_k127_3157770_2 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 7.66e-322 997.0
HFD3_k127_3157770_20 CAAX protease self-immunity - - - 0.00000000000000000000000000000000000009978 153.0
HFD3_k127_3157770_21 Transcriptional regulator - - - 0.000000000000000000000000000000000002766 145.0
HFD3_k127_3157770_22 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000001101 111.0
HFD3_k127_3157770_24 Tetratricopeptide repeat - - - 0.00000000000000005517 88.0
HFD3_k127_3157770_25 Thioredoxin K03672 - 1.8.1.8 0.000000000000002595 83.0
HFD3_k127_3157770_26 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000000004331 72.0
HFD3_k127_3157770_27 Metallo-peptidase family M12B Reprolysin-like - - - 0.000001142 56.0
HFD3_k127_3157770_3 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 3.899e-311 981.0
HFD3_k127_3157770_4 TIGRFAM ATP-dependent helicase HrpB K03579 - 3.6.4.13 4.039e-274 867.0
HFD3_k127_3157770_5 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 1.31e-201 636.0
HFD3_k127_3157770_6 Phosphoglycerate kinase K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005639 602.0
HFD3_k127_3157770_7 Belongs to the sulfate adenylyltransferase family K00958,K13811 - 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 588.0
HFD3_k127_3157770_8 FAD dependent oxidoreductase K16885 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008641 554.0
HFD3_k127_3157770_9 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000858 492.0
HFD3_k127_3171643_0 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992,K19341 - - 0.0000000000000000000000000000000000000000000000000000002 205.0
HFD3_k127_3171643_1 NosL K19342 - - 0.00000000000000000000000000000000000001523 151.0
HFD3_k127_3171643_2 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000008684 152.0
HFD3_k127_3171643_3 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000001353 134.0
HFD3_k127_3171643_4 NosL - - - 0.0000000000000000000000005648 111.0
HFD3_k127_3171643_5 Transglutaminase/protease-like homologues - - - 0.0000000000000000000001196 112.0
HFD3_k127_3171643_6 Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c - GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - 0.00000001039 63.0
HFD3_k127_3171643_7 Protein of unknown function (DUF1573) - - - 0.00000113 52.0
HFD3_k127_3181679_0 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 367.0
HFD3_k127_3181679_1 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000001068 89.0
HFD3_k127_3181679_2 Integral membrane protein TerC family - - - 0.000000000000001986 78.0
HFD3_k127_3181679_3 membrane K05794 - - 0.00000000000002 76.0
HFD3_k127_3181679_4 PFAM Transmembrane proteins 14C - - - 0.00000001246 60.0
HFD3_k127_3181679_5 Transcription factor zinc-finger K09981 - - 0.0002575 49.0
HFD3_k127_3181694_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 7.462e-261 812.0
HFD3_k127_3181694_1 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 417.0
HFD3_k127_3181694_10 ABC transporter K17076 - - 0.00000000007741 65.0
HFD3_k127_3181694_2 ABC transporter K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004352 253.0
HFD3_k127_3181694_3 PFAM Transketolase, C-terminal domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000001553 222.0
HFD3_k127_3181694_4 Peptidase family M23 K21471 GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000003614 220.0
HFD3_k127_3181694_5 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000000000000000000002001 194.0
HFD3_k127_3181694_6 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.00000000000000000000000000000000001015 137.0
HFD3_k127_3181694_7 ABC-type polar amino acid transport system ATPase component K02028 - 3.6.3.21 0.000000000000000000000000000000001007 134.0
HFD3_k127_3181694_8 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K01083,K06131,K06915 - 3.1.3.8 0.00000000000000000000000006524 118.0
HFD3_k127_3181694_9 abc transporter atp-binding protein K09972 - - 0.0000000000005176 70.0
HFD3_k127_3197741_0 Uncharacterised protein family (UPF0182) K09118 - - 2.378e-299 943.0
HFD3_k127_3197741_1 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000001323 125.0
HFD3_k127_3197741_2 - - - - 0.0000000000005132 73.0
HFD3_k127_3197741_3 anaerobic respiration - - - 0.000000308 53.0
HFD3_k127_3199403_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 7.19e-236 742.0
HFD3_k127_3199403_1 Domain of unknown function (DUF4139) - - - 7.006e-202 638.0
HFD3_k127_3199403_10 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000005918 226.0
HFD3_k127_3199403_11 nucleotidyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000001112 203.0
HFD3_k127_3199403_12 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000000000001563 196.0
HFD3_k127_3199403_13 TPM domain - - - 0.000000000000000000000000000000000000000003278 166.0
HFD3_k127_3199403_14 - - - - 0.000000000000000000000000002128 119.0
HFD3_k127_3199403_15 part of a sulfur-relay system K11179 - - 0.000000000000000000000000007012 113.0
HFD3_k127_3199403_16 Glutaredoxin K03676 - - 0.0000000000000004046 78.0
HFD3_k127_3199403_17 radical SAM domain protein - - - 0.0000001027 58.0
HFD3_k127_3199403_19 Putative zinc-finger - - - 0.0006531 51.0
HFD3_k127_3199403_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003723 519.0
HFD3_k127_3199403_3 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 458.0
HFD3_k127_3199403_4 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 358.0
HFD3_k127_3199403_5 TIGRFAM 2-oxoacid acceptor oxidoreductase, beta subunit, pyruvate 2-ketoisovalerate family K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 344.0
HFD3_k127_3199403_6 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005696 306.0
HFD3_k127_3199403_7 PFAM Isochorismatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003112 277.0
HFD3_k127_3199403_8 Appr-1'-p processing enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000001355 232.0
HFD3_k127_3199403_9 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000002432 225.0
HFD3_k127_3199849_0 Aminotransferase class I and II K14261 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 601.0
HFD3_k127_3199849_1 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008069 591.0
HFD3_k127_3199849_2 Homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 552.0
HFD3_k127_3199849_3 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 484.0
HFD3_k127_3199849_4 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 378.0
HFD3_k127_3199849_5 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065,K13252 - 2.1.3.3,2.1.3.6,2.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 341.0
HFD3_k127_3199849_6 proteolysis K21140 - 3.13.1.6 0.0000000000000000000000002719 110.0
HFD3_k127_3199849_7 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000000001277 100.0
HFD3_k127_3199849_8 TIGRFAM MoaD family protein K03636 - - 0.0000001712 53.0
HFD3_k127_320491_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 610.0
HFD3_k127_320491_1 ATPase, AAA K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 466.0
HFD3_k127_320491_2 YmdB-like protein K02029,K02030,K09769 GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000016 260.0
HFD3_k127_3222357_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 5.986e-219 692.0
HFD3_k127_3222357_1 CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.0000000000000000000000000000000000000000000000000000000005907 205.0
HFD3_k127_3222357_2 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000006109 153.0
HFD3_k127_3222357_3 polynucleotide 5'-hydroxyl-kinase activity K06947 - - 0.0000000000000000000000000000000000003833 153.0
HFD3_k127_3246938_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004214 355.0
HFD3_k127_3246938_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 346.0
HFD3_k127_3246938_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 317.0
HFD3_k127_3246938_3 CO dehydrogenase K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008172 265.0
HFD3_k127_3246938_4 Response regulator receiver domain K03413 - - 0.00000000000000000000000000000000000000000000000005898 180.0
HFD3_k127_3250218_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1439.0
HFD3_k127_3250218_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005021 280.0
HFD3_k127_3257983_0 Domains HisKA, HATPase_c - - - 0.00000000000000000000000000000000000000000000000000000000000007949 222.0
HFD3_k127_3257983_1 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000002939 180.0
HFD3_k127_3257983_2 Domain of unknown function (DUF4253) - - - 0.000000000000000000000000000000000005204 146.0
HFD3_k127_3257983_3 Rhodanese Homology Domain - - - 0.0000000000000000000000000000004556 127.0
HFD3_k127_3257983_4 Cysteine-rich small domain K07162 - - 0.0000000000000000000003692 97.0
HFD3_k127_3257983_5 Rhodanese Homology Domain - - - 0.0000000000001915 70.0
HFD3_k127_3257983_6 YtkA-like - - - 0.00000002066 61.0
HFD3_k127_3257983_7 signal transduction protein with EFhand domain - - - 0.00001355 48.0
HFD3_k127_3292114_0 - - - - 0.000000000000000000000000000000000000000000000007444 175.0
HFD3_k127_3292114_1 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000001131 164.0
HFD3_k127_3292114_2 Formiminotransferase-cyclodeaminase - - - 0.000000000000000000000000000000000000000006614 162.0
HFD3_k127_3292114_3 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000008716 100.0
HFD3_k127_3292114_4 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000001691 51.0
HFD3_k127_3293061_0 - - - - 4.033e-195 616.0
HFD3_k127_3293061_1 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006332 531.0
HFD3_k127_3293061_10 Methyltransferase domain - - - 0.000000000000002445 77.0
HFD3_k127_3293061_11 RibD C-terminal domain - - - 0.00000000000001438 79.0
HFD3_k127_3293061_12 SnoaL-like domain - - - 0.000005069 48.0
HFD3_k127_3293061_2 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007555 525.0
HFD3_k127_3293061_3 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005062 326.0
HFD3_k127_3293061_4 3-demethylubiquinone-9 3-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002544 249.0
HFD3_k127_3293061_5 RibD C-terminal domain K00287 - 1.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000005044 237.0
HFD3_k127_3293061_6 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000002215 216.0
HFD3_k127_3293061_7 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000195 186.0
HFD3_k127_3293061_8 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000009483 189.0
HFD3_k127_3293061_9 RibD C-terminal domain - - - 0.0000000000000003463 79.0
HFD3_k127_329990_0 TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 436.0
HFD3_k127_329990_1 Glyoxalase-like domain K06996 - - 0.0000000000000000000000000000000000000004083 152.0
HFD3_k127_329990_2 RNA recognition motif - - - 0.0000000000000000000000000008334 116.0
HFD3_k127_329990_3 integral membrane protein - - - 0.00000000001482 66.0
HFD3_k127_329990_4 structural constituent of ribosome K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000005596 66.0
HFD3_k127_329990_5 - - - - 0.00000001008 62.0
HFD3_k127_3305151_0 PFAM Bile acid sodium symporter K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 509.0
HFD3_k127_3305151_1 Uncharacterized protein family (UPF0051) K07033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 333.0
HFD3_k127_3305151_2 RecF/RecN/SMC N terminal domain K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001075 252.0
HFD3_k127_3305151_3 Protein of unknown function (DUF3795) - - - 0.0000000000000000000009341 99.0
HFD3_k127_3305151_4 - - - - 0.000000000000000000003398 94.0
HFD3_k127_3305151_6 Belongs to the HesB IscA family K15724 - - 0.00000002041 57.0
HFD3_k127_3315404_0 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 537.0
HFD3_k127_3315404_1 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006585 430.0
HFD3_k127_3315404_2 Pfam:Arch_ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007562 263.0
HFD3_k127_3315404_3 regulator, PATAN and FRGAF domain-containing - - - 0.00000000000000000000000000000000000000000000000000000000000000000003067 246.0
HFD3_k127_3315404_4 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000000000000000005796 223.0
HFD3_k127_3315404_5 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000000000969 140.0
HFD3_k127_3315404_6 PFAM CheW domain protein K03408 - - 0.0000000000000000000000005951 112.0
HFD3_k127_3315404_7 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000001798 84.0
HFD3_k127_3315404_8 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000006539 57.0
HFD3_k127_3315404_9 regulator, PATAN and FRGAF domain-containing - - - 0.00002196 47.0
HFD3_k127_3319693_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 5.4e-323 1000.0
HFD3_k127_3319693_1 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 3.585e-314 986.0
HFD3_k127_3319693_10 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000003355 162.0
HFD3_k127_3319693_11 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.000000000000000000000000000000000000004796 147.0
HFD3_k127_3319693_12 Protein of unknown function (DUF1638) - - - 0.00000000000000000000000000134 121.0
HFD3_k127_3319693_13 - - - - 0.00000000000001438 79.0
HFD3_k127_3319693_15 DsrE/DsrF-like family - - - 0.00003329 51.0
HFD3_k127_3319693_16 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00007437 47.0
HFD3_k127_3319693_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 1.474e-258 810.0
HFD3_k127_3319693_3 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 329.0
HFD3_k127_3319693_4 nadp oxidoreductase, coenzyme f420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007814 326.0
HFD3_k127_3319693_5 protein involved in outer membrane biogenesis K07290 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0032386,GO:0032879,GO:0032880,GO:0033157,GO:0044464,GO:0050789,GO:0051049,GO:0051223,GO:0060341,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:0090313,GO:1903533,GO:1903827,GO:1905475 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 305.0
HFD3_k127_3319693_6 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007079 302.0
HFD3_k127_3319693_7 Methylcobalamin coenzyme M methyltransferase K01599,K14080 - 2.1.1.246,4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001525 277.0
HFD3_k127_3319693_8 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031004,GO:0031224,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000007961 239.0
HFD3_k127_3319693_9 PFAM B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000004521 223.0
HFD3_k127_3322502_0 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008414 436.0
HFD3_k127_3322502_1 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007683 297.0
HFD3_k127_3322502_2 ferrous iron binding K06990,K09141 - - 0.00000000000000000000000000000000000000000000000002715 185.0
HFD3_k127_3322502_3 Peptidase family M50 - - - 0.00000000000000000000000000000007171 129.0
HFD3_k127_3332728_0 ATP synthase alpha/beta family, nucleotide-binding domain K02118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 426.0
HFD3_k127_3332728_1 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 400.0
HFD3_k127_3332728_2 ATP synthase subunit D K02120 - - 0.000000000000000000000000000000000000000000000000000000000000000000003193 241.0
HFD3_k127_3332728_3 deoxyhypusine monooxygenase activity K05386 - - 0.0000000000000000001092 94.0
HFD3_k127_3332728_4 OsmC-like protein K07397 - - 0.00000000000002671 77.0
HFD3_k127_3339348_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009485 384.0
HFD3_k127_3339348_1 PFAM Cold-shock protein, DNA-binding K03704 - - 0.00000000000000000000000000263 112.0
HFD3_k127_3339348_2 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.00000000000000000000000126 106.0
HFD3_k127_3339348_3 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000000009222 65.0
HFD3_k127_3355152_0 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 604.0
HFD3_k127_3355152_1 Belongs to the peptidase M50B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006816 463.0
HFD3_k127_3355152_11 Cytochrome c - - - 0.0000000000000000241 83.0
HFD3_k127_3355152_13 - - - - 0.0000008334 55.0
HFD3_k127_3355152_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 397.0
HFD3_k127_3355152_3 galactose-1-phosphate uridylyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 357.0
HFD3_k127_3355152_4 Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons K01563 GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.8.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 290.0
HFD3_k127_3355152_5 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000006166 211.0
HFD3_k127_3355152_6 - - - - 0.0000000000000000000000000000000000000000000000000000002305 211.0
HFD3_k127_3355152_7 pfam nudix - - - 0.000000000000000000000000000000000000000000000000000003944 195.0
HFD3_k127_3355152_8 NADH dehydrogenase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000004906 188.0
HFD3_k127_3355152_9 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000001443 115.0
HFD3_k127_3357432_0 Sugar (and other) transporter K03446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 598.0
HFD3_k127_3357432_1 HlyD membrane-fusion protein of T1SS K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 329.0
HFD3_k127_3360305_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199 591.0
HFD3_k127_3360305_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007958 314.0
HFD3_k127_3360305_2 PFAM Cysteine-rich domain K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000184 259.0
HFD3_k127_3360305_3 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000003248 136.0
HFD3_k127_3360305_4 regulatory protein, FmdB family - - - 0.000000000001874 71.0
HFD3_k127_3360305_5 monooxygenase activity K00688,K15760,K16157,K16242,K18223,K22353,K22357 GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0008150,GO:0008152,GO:0009987,GO:0015049,GO:0015050,GO:0015947,GO:0016491,GO:0016705,GO:0016709,GO:0032991,GO:0043446,GO:0044237,GO:0055114,GO:0071704,GO:1902494 1.14.13.227,1.14.13.236,1.14.13.25,1.14.13.69,2.4.1.1 0.0000006938 56.0
HFD3_k127_3400079_0 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000003337 220.0
HFD3_k127_3400079_1 Transcriptional regulator K07722 - - 0.00000000000000000000000000000000000000000000000000001786 191.0
HFD3_k127_3400079_2 - - - - 0.00000000000000000000000000000002356 135.0
HFD3_k127_3400079_3 Protein involved in meta-pathway of phenol degradation - - - 0.00000000001468 75.0
HFD3_k127_3400079_4 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.000000004258 59.0
HFD3_k127_3407252_0 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006025 313.0
HFD3_k127_3407252_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009548 261.0
HFD3_k127_3407252_2 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000243 214.0
HFD3_k127_3407252_3 YGGT family K02221 - - 0.00000000000000000000000000006643 118.0
HFD3_k127_3407252_4 DivIVA protein K04074 - - 0.000000000000000000000000224 111.0
HFD3_k127_3407252_5 Belongs to the UPF0235 family K09131 - - 0.000000000000000000000004776 106.0
HFD3_k127_3407252_6 Radical SAM domain protein - - - 0.0000000000000008557 78.0
HFD3_k127_3408104_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.23e-218 684.0
HFD3_k127_3408104_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 399.0
HFD3_k127_3408104_2 Protein of unknown function (DUF1385) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 336.0
HFD3_k127_3408104_3 Binds the 23S rRNA K02909 GO:0008150,GO:0040007 - 0.0000000000000000000000001641 108.0
HFD3_k127_3431379_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 512.0
HFD3_k127_3431379_1 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008058 292.0
HFD3_k127_3431379_3 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000009576 83.0
HFD3_k127_3431379_6 methyltransferase activity - - - 0.0007259 45.0
HFD3_k127_344659_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1045.0
HFD3_k127_344659_1 Lipopolysaccharide-assembly - - - 0.0000002482 55.0
HFD3_k127_3457742_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006582 574.0
HFD3_k127_3457742_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008328 281.0
HFD3_k127_3457742_2 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000008045 255.0
HFD3_k127_3457742_3 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000000005327 213.0
HFD3_k127_3457742_4 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.00000000000000001443 82.0
HFD3_k127_34784_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652,K01906 - 2.3.1.29,2.3.1.47,6.2.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005241 403.0
HFD3_k127_34784_1 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001173 257.0
HFD3_k127_34784_2 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000004822 239.0
HFD3_k127_34784_3 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000495 235.0
HFD3_k127_34784_4 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000009781 225.0
HFD3_k127_34784_5 6-carboxyhexanoate--CoA ligase K01906 - 6.2.1.14 0.00000000000000000000000000000006671 127.0
HFD3_k127_34784_6 electron transfer activity K00428 - 1.11.1.5 0.00000000000000005084 85.0
HFD3_k127_3486707_0 Major Facilitator Superfamily K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 545.0
HFD3_k127_3486707_1 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782 393.0
HFD3_k127_3486707_2 auxin-activated signaling pathway K07088 - - 0.00000000000000000000000000000000000000000000000000000000001331 217.0
HFD3_k127_3486707_3 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000002622 63.0
HFD3_k127_3486707_4 - - - - 0.0001146 49.0
HFD3_k127_3497045_0 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11779,K11784 - 1.21.98.1,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003928 469.0
HFD3_k127_3497045_1 MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 387.0
HFD3_k127_3497045_2 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007534 355.0
HFD3_k127_3497045_3 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001886 275.0
HFD3_k127_3527833_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 6.301e-270 841.0
HFD3_k127_3527833_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007821 493.0
HFD3_k127_3527833_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007088 340.0
HFD3_k127_3527833_3 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334,K18330,K22340 - 1.12.1.3,1.17.1.11,1.6.5.3 0.0000000000000000000000000000000000000000000000001794 181.0
HFD3_k127_3527833_4 Ferredoxin K17992 - 1.12.1.3 0.0000000000000000000000000000000000000011 150.0
HFD3_k127_3527833_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000001526 142.0
HFD3_k127_3527833_6 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000003875 126.0
HFD3_k127_3527833_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000007737 96.0
HFD3_k127_356573_0 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006096 437.0
HFD3_k127_356573_1 PFAM ABC transporter related K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000841 402.0
HFD3_k127_356573_2 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001789 281.0
HFD3_k127_356573_3 PFAM Radical SAM domain protein K22227 - - 0.0000000000000000000000000000000000000000000000000000009415 194.0
HFD3_k127_356573_4 Universal stress protein family - - - 0.0000000000000000000000000000000000003777 146.0
HFD3_k127_356573_5 Iron-sulfur cluster-binding domain - - - 0.00000000115 60.0
HFD3_k127_356573_6 Transposase, IS605 OrfB family - - - 0.0000639 48.0
HFD3_k127_35787_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1131.0
HFD3_k127_35787_1 cysteine protease - - - 2.315e-227 721.0
HFD3_k127_35787_10 - - - - 0.0000000000000000000000000003881 117.0
HFD3_k127_35787_11 CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000001893 114.0
HFD3_k127_35787_12 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000001779 107.0
HFD3_k127_35787_13 - - - - 0.00000000000000000000003358 108.0
HFD3_k127_35787_14 HsdM N-terminal domain K03427 - 2.1.1.72 0.00000000000000000000007953 98.0
HFD3_k127_35787_15 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000002821 97.0
HFD3_k127_35787_16 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000002172 69.0
HFD3_k127_35787_2 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 542.0
HFD3_k127_35787_3 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 403.0
HFD3_k127_35787_4 PFAM peptidase C14, caspase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005051 391.0
HFD3_k127_35787_5 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000004517 222.0
HFD3_k127_35787_6 - - - - 0.000000000000000000000000000000000000000000000002961 192.0
HFD3_k127_35787_7 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000005917 183.0
HFD3_k127_35787_8 cysteine-type peptidase activity K21471 - - 0.000000000000000000000000000000000000000000008468 176.0
HFD3_k127_35787_9 - - - - 0.00000000000000000000000000000000000006006 149.0
HFD3_k127_3586571_0 NnrU protein K21310 - 2.1.1.334 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 314.0
HFD3_k127_3586571_1 PFAM glycoside hydrolase, family 10 K01181 - 3.2.1.8 0.000000000000000000000000000000000000000000001344 172.0
HFD3_k127_3586571_2 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K00657,K07023 - 2.3.1.57 0.0000000000000000000000001296 108.0
HFD3_k127_3586571_3 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.0000008227 55.0
HFD3_k127_3610731_0 Mn2 dependent serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004389 404.0
HFD3_k127_3610731_1 adenylylsulfate kinase activity K00860,K00955 - 2.7.1.25,2.7.7.4 0.000000000000000000000000000000000000000000000009319 177.0
HFD3_k127_3610731_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.0000000000000000000000000000002828 126.0
HFD3_k127_3656532_0 PFAM extracellular solute-binding protein, family 5 K02035,K13893 - - 3.523e-204 647.0
HFD3_k127_3656532_1 ATPases associated with a variety of cellular activities K01990,K11050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 321.0
HFD3_k127_3656532_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000002658 214.0
HFD3_k127_3656532_3 PFAM Preprotein translocase SecG subunit K03075 - - 0.000000000000000000001565 98.0
HFD3_k127_3682116_0 aconitate hydratase K01681 - 4.2.1.3 1.072e-281 878.0
HFD3_k127_3682116_1 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 407.0
HFD3_k127_3682116_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007694 325.0
HFD3_k127_3682116_3 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000305 138.0
HFD3_k127_371005_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1085.0
HFD3_k127_371005_1 Uncharacterized protein conserved in bacteria (DUF2344) - - - 2.109e-224 723.0
HFD3_k127_371005_10 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 518.0
HFD3_k127_371005_11 Actin K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 488.0
HFD3_k127_371005_12 Putative RNA methylase family UPF0020 K07444,K12297 - 2.1.1.173,2.1.1.264 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 488.0
HFD3_k127_371005_13 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 416.0
HFD3_k127_371005_14 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000755 404.0
HFD3_k127_371005_15 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 340.0
HFD3_k127_371005_16 fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 324.0
HFD3_k127_371005_17 Belongs to the SEDS family K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007315 320.0
HFD3_k127_371005_18 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005337 310.0
HFD3_k127_371005_19 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002162 285.0
HFD3_k127_371005_2 transporter antisigma-factor antagonist STAS K03321 - - 2.464e-214 681.0
HFD3_k127_371005_20 PFAM Integral membrane protein TerC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001559 279.0
HFD3_k127_371005_21 Cytidylate kinase-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001941 267.0
HFD3_k127_371005_22 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007074 264.0
HFD3_k127_371005_23 3-beta hydroxysteroid dehydrogenase K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000002809 265.0
HFD3_k127_371005_24 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000000000001005 210.0
HFD3_k127_371005_25 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K00950,K13940 - 2.7.6.3,4.1.2.25 0.000000000000000000000000000000000000000000011 168.0
HFD3_k127_371005_26 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000003022 168.0
HFD3_k127_371005_27 Diguanylate cyclase with GAF sensor - - - 0.0000000000000000000000000000000000006896 155.0
HFD3_k127_371005_28 PA14 domain - - - 0.00000000000000000000000000000581 133.0
HFD3_k127_371005_29 RDD family - - - 0.0000000000000000003036 94.0
HFD3_k127_371005_3 Conserved hypothetical protein 698 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 617.0
HFD3_k127_371005_30 - - - - 0.0000000000000000004801 87.0
HFD3_k127_371005_31 - - - - 0.000000000000000002977 89.0
HFD3_k127_371005_32 rod shape-determining protein MreD K03571 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.0000000000382 71.0
HFD3_k127_371005_33 Cache domain - - - 0.00000001312 58.0
HFD3_k127_371005_34 diguanylate cyclase K13069 - 2.7.7.65 0.0001146 49.0
HFD3_k127_371005_35 Uncharacterized protein family, UPF0114 - - - 0.0003865 49.0
HFD3_k127_371005_4 PFAM aminotransferase, class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008235 599.0
HFD3_k127_371005_5 Ribonuclease E/G family K08301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 588.0
HFD3_k127_371005_6 PFAM aminotransferase, class I and II K10206 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0010285,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0033362,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006456 580.0
HFD3_k127_371005_7 Argininosuccinate lyase C-terminal K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 570.0
HFD3_k127_371005_8 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009458 578.0
HFD3_k127_371005_9 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 530.0
HFD3_k127_3770092_0 Ftsk_gamma K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 394.0
HFD3_k127_3770092_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000813 302.0
HFD3_k127_3770092_2 - - - - 0.0000000000000000001971 93.0
HFD3_k127_3796_0 Glycosyltransferase family 9 (heptosyltransferase) K02843,K02849 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 383.0
HFD3_k127_3796_1 electron transfer activity K05337,K17247 - - 0.0000000000000000000003138 98.0
HFD3_k127_3806251_0 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 439.0
HFD3_k127_3806251_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 445.0
HFD3_k127_3806251_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 380.0
HFD3_k127_3806251_3 Cytochrome C assembly protein - - - 0.000005792 49.0
HFD3_k127_382285_0 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000933 551.0
HFD3_k127_382285_1 Beta Propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 534.0
HFD3_k127_382285_2 PFAM ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 387.0
HFD3_k127_382285_3 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 344.0
HFD3_k127_382285_4 - - - - 0.0000000000000000000000000000000000004122 147.0
HFD3_k127_3854275_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1060.0
HFD3_k127_3854275_1 isocitrate dehydrogenase activity K00031 GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007229 570.0
HFD3_k127_3854275_10 Chemotaxis signal transduction protein K03408 - - 0.0000000000000000007235 93.0
HFD3_k127_3854275_11 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000002926 64.0
HFD3_k127_3854275_2 two-component system, chemotaxis family, sensor kinase CheA with response regulator domain K02487,K06596 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 477.0
HFD3_k127_3854275_3 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660,K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 362.0
HFD3_k127_3854275_4 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 313.0
HFD3_k127_3854275_5 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005387 286.0
HFD3_k127_3854275_6 response regulator K02658 - - 0.00000000000000000000000000000000000000000000000000000000000228 225.0
HFD3_k127_3854275_7 Twitching motility two-component system response regulator PilH K02658 - - 0.0000000000000000000000000000000000000002068 152.0
HFD3_k127_3854275_8 Smr domain - - - 0.00000000000000000000000000000003296 127.0
HFD3_k127_3854275_9 response regulator - - - 0.000000000000000000000000002076 126.0
HFD3_k127_3896110_0 response regulator K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 538.0
HFD3_k127_3896110_1 May be involved in recombinational repair of damaged DNA K03631,K13582 GO:0000724,GO:0000725,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009295,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 467.0
HFD3_k127_3896110_10 Diguanylate cyclase - - - 0.0000000000000000000008949 111.0
HFD3_k127_3896110_11 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.0000000000000002405 82.0
HFD3_k127_3896110_12 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.0000000000000003401 80.0
HFD3_k127_3896110_13 Yip1 domain - - - 0.00000000002333 70.0
HFD3_k127_3896110_14 peptidyl-prolyl cis-trans isomerase K03771 - 5.2.1.8 0.00000000004341 72.0
HFD3_k127_3896110_15 Histidine kinase K02482 - 2.7.13.3 0.0000002762 64.0
HFD3_k127_3896110_16 Transglycosylase K08309 - - 0.00008037 53.0
HFD3_k127_3896110_17 Thioesterase domain - - - 0.000703 42.0
HFD3_k127_3896110_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 454.0
HFD3_k127_3896110_3 Cys/Met metabolism PLP-dependent enzyme K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 415.0
HFD3_k127_3896110_4 Cysteine synthase A K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 377.0
HFD3_k127_3896110_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 308.0
HFD3_k127_3896110_6 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005927 295.0
HFD3_k127_3896110_7 Surface antigen K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 299.0
HFD3_k127_3896110_8 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000002227 237.0
HFD3_k127_3896110_9 Alpha beta hydrolase - - - 0.00000000000000000000000004825 115.0
HFD3_k127_3899126_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 2.615e-255 800.0
HFD3_k127_3899126_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005227 424.0
HFD3_k127_3899126_2 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 329.0
HFD3_k127_3899126_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000003719 203.0
HFD3_k127_3899126_4 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000489 132.0
HFD3_k127_3899126_5 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000006251 62.0
HFD3_k127_3913510_0 Nitrogenase component 1 type Oxidoreductase K02587 - - 2.375e-280 884.0
HFD3_k127_3913510_1 Nitrogenase component 1 type Oxidoreductase K02586 - 1.18.6.1 7.164e-233 728.0
HFD3_k127_3913510_10 reductase, alpha subunit K00394 - 1.8.99.2 0.0000000001433 61.0
HFD3_k127_3913510_11 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000001942 56.0
HFD3_k127_3913510_12 PFAM CBS domain containing protein - - - 0.00000005622 61.0
HFD3_k127_3913510_13 - - - - 0.0009749 51.0
HFD3_k127_3913510_2 This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation K02591 - 1.18.6.1 4.251e-223 701.0
HFD3_k127_3913510_3 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588,K04037,K11333 - 1.18.6.1,1.3.7.14,1.3.7.15,1.3.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003863 475.0
HFD3_k127_3913510_4 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 290.0
HFD3_k127_3913510_5 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000006048 210.0
HFD3_k127_3913510_6 Uncharacterised protein family (UPF0158) - - - 0.0000000000000000000000000000000000000002719 153.0
HFD3_k127_3913510_8 Sulphur transport K07112 - - 0.0000000000000005708 81.0
HFD3_k127_3913510_9 Protein of unknown function (DUF2892) - - - 0.0000000000000167 75.0
HFD3_k127_3913933_0 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 462.0
HFD3_k127_3913933_1 Sigma-54 interaction domain K02481 - - 0.000000000002375 75.0
HFD3_k127_3933640_0 COGs COG3677 Transposase and inactivated derivatives K07480 - - 0.0000000000000000000000000000000000000000000000000000004542 201.0
HFD3_k127_3933640_1 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000002031 187.0
HFD3_k127_3933640_2 recombinase XerD K04763 - - 0.000000000000000000000004098 110.0
HFD3_k127_3933640_3 Protein of unknown function (DUF3761) - - - 0.0000000000000000007202 92.0
HFD3_k127_3933640_4 PFAM IS1 transposase K07480 - - 0.000000000004365 66.0
HFD3_k127_3933640_5 Patatin-like phospholipase K07001 - - 0.0000003795 54.0
HFD3_k127_3935442_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 384.0
HFD3_k127_3935442_1 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 330.0
HFD3_k127_3935442_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000002309 239.0
HFD3_k127_3935684_0 Anthranilate synthase component I K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 452.0
HFD3_k127_3935684_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 325.0
HFD3_k127_3935684_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000007669 231.0
HFD3_k127_3935684_3 DNA polymerase III, delta subunit, C terminal K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000001154 235.0
HFD3_k127_3935684_4 PSP1 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000006455 220.0
HFD3_k127_3935684_5 AAA domain - - - 0.0000000001064 75.0
HFD3_k127_3936498_0 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 3.62e-265 836.0
HFD3_k127_3936498_1 acetyl-CoA catabolic process K00197 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008175 463.0
HFD3_k127_3936498_2 one-carbon metabolic process K00194,K00198 - 1.2.7.4,2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006828 353.0
HFD3_k127_3936498_3 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006605 332.0
HFD3_k127_3936498_4 thymidylate synthase (FAD) activity K03465 - 2.1.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 312.0
HFD3_k127_3936498_5 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002588 272.0
HFD3_k127_3936498_6 Domain of unknown function (DUF2520) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000319 262.0
HFD3_k127_3936498_7 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000007587 190.0
HFD3_k127_3936498_8 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K18331 - 1.12.1.3,1.6.5.3 0.00000000000000000000000000000000000009171 145.0
HFD3_k127_3936498_9 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000001016 86.0
HFD3_k127_3939432_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.083e-213 677.0
HFD3_k127_3939432_1 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006384 269.0
HFD3_k127_3969337_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 5.128e-249 779.0
HFD3_k127_3969337_1 UDP-N-acetylmuramate-L-alanine ligase activity K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 600.0
HFD3_k127_3969337_10 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 352.0
HFD3_k127_3969337_11 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 318.0
HFD3_k127_3969337_12 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003381 320.0
HFD3_k127_3969337_13 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004408 285.0
HFD3_k127_3969337_14 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008261 282.0
HFD3_k127_3969337_15 Cell wall formation K00075 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000002064 254.0
HFD3_k127_3969337_16 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.0000000000000000000000000000000000000000000000000000001885 201.0
HFD3_k127_3969337_17 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000002567 197.0
HFD3_k127_3969337_18 Acyl-transferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000005141 183.0
HFD3_k127_3969337_19 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000000000001649 163.0
HFD3_k127_3969337_2 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 488.0
HFD3_k127_3969337_20 ribosomal large subunit export from nucleus - - - 0.000000000000000000000000000000000000000006324 160.0
HFD3_k127_3969337_21 Cupin domain K11312 - - 0.00000000000000000000000000000000000006997 145.0
HFD3_k127_3969337_22 SMART HNH nuclease K07451 - - 0.0000000000000000000000000000000000003235 143.0
HFD3_k127_3969337_23 Thiamine-binding protein - - - 0.00000000000000000000000000000006349 127.0
HFD3_k127_3969337_24 STAS domain K04749 - - 0.000000003614 63.0
HFD3_k127_3969337_25 Essential cell division protein - - - 0.000001025 55.0
HFD3_k127_3969337_3 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009343 469.0
HFD3_k127_3969337_4 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 467.0
HFD3_k127_3969337_5 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 406.0
HFD3_k127_3969337_6 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 395.0
HFD3_k127_3969337_7 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 375.0
HFD3_k127_3969337_8 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 369.0
HFD3_k127_3969337_9 Cell wall formation K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 359.0
HFD3_k127_3971675_0 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 9.985e-204 645.0
HFD3_k127_3971675_1 phosphorelay signal transduction system K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 408.0
HFD3_k127_3971675_2 CBS domain containing protein K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 352.0
HFD3_k127_3971675_3 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000032 115.0
HFD3_k127_3978584_0 Iron-sulfur cluster-binding domain K06871 - - 7.852e-218 683.0
HFD3_k127_3978584_1 Protein of unknown function (DUF3313) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001189 245.0
HFD3_k127_3978584_2 Putative MetA-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003325 241.0
HFD3_k127_3978584_3 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000005972 173.0
HFD3_k127_3984123_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00850,K00895,K21071 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 471.0
HFD3_k127_3984123_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004698 347.0
HFD3_k127_3984123_2 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004871 319.0
HFD3_k127_3984123_3 HrcA protein C terminal domain K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 312.0
HFD3_k127_3984123_4 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000006766 205.0
HFD3_k127_3984123_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000001511 127.0
HFD3_k127_3984123_7 - - - - 0.000000000002345 70.0
HFD3_k127_3996868_0 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides - - - 0.0000000000000000000000000000000000000000000000000000000000000000001816 238.0
HFD3_k127_3996868_1 Cysteine-rich domain K08264 - 1.8.98.1 0.000000000000000000000000000000000000000000108 168.0
HFD3_k127_3996868_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000944 111.0
HFD3_k127_3996868_3 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.00000000004286 63.0
HFD3_k127_3996868_4 Nitrate reductase gamma subunit - - - 0.000000223 61.0
HFD3_k127_4008223_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 2.394e-218 696.0
HFD3_k127_4008223_1 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003509 381.0
HFD3_k127_4008223_2 PFAM iron dependent repressor K03709 - - 0.00000000000000000000000000000000000000000000000000000001496 205.0
HFD3_k127_4008223_3 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000002983 168.0
HFD3_k127_4008223_4 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000002492 144.0
HFD3_k127_4008223_5 Domain of unknown function (DUF4416) - - - 0.00000000000000000000000000000000001467 142.0
HFD3_k127_4008223_6 transcriptional regulator, Rrf2 family - - - 0.000000000000000001437 89.0
HFD3_k127_4021553_0 domain, Protein K12373 - 3.2.1.52 9.012e-316 974.0
HFD3_k127_4021553_1 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 422.0
HFD3_k127_4021553_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005798 254.0
HFD3_k127_4021553_3 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000000000000000002735 203.0
HFD3_k127_4021553_4 Eco57I restriction-modification methylase - - - 0.00000000000000000000000000000000000000878 148.0
HFD3_k127_4021553_5 Belongs to the sulfur carrier protein TusA family - - - 0.00000000001628 65.0
HFD3_k127_4021553_6 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000001408 56.0
HFD3_k127_4021553_8 TniQ - - - 0.00004516 53.0
HFD3_k127_4028274_0 - - - - 0.0 1697.0
HFD3_k127_4028274_1 - - - - 0.0 1288.0
HFD3_k127_4028274_10 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000000007372 182.0
HFD3_k127_4028274_11 dihydrofolate reductase activity - - - 0.0000000000000000000000000000000006399 131.0
HFD3_k127_4028274_12 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000000000000000000000758 132.0
HFD3_k127_4028274_13 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000004142 136.0
HFD3_k127_4028274_14 Involved in the tonB-independent uptake of proteins K01406,K01771,K03641 - 3.4.24.40,4.6.1.13 0.00000000000000000000000000001775 137.0
HFD3_k127_4028274_15 OmpA family K03640 - - 0.000000000000000000000000001573 114.0
HFD3_k127_4028274_16 DSBA-like thioredoxin domain - - - 0.00000000000000000000000004317 111.0
HFD3_k127_4028274_17 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.0000000000000000000002579 106.0
HFD3_k127_4028274_18 Transposase IS200 like K07491 - - 0.000000000009485 69.0
HFD3_k127_4028274_19 PFAM transposase IS4 family protein - - - 0.00000000002734 65.0
HFD3_k127_4028274_2 photosystem II stabilization - - - 9.567e-289 908.0
HFD3_k127_4028274_20 Protein of unknown function (DUF1360) - - - 0.00000000006684 71.0
HFD3_k127_4028274_21 homolog of phage Mu protein gp47 - - - 0.00000000017 71.0
HFD3_k127_4028274_22 Glycosyl hydrolases family 16 - - - 0.000000199 64.0
HFD3_k127_4028274_23 amine dehydrogenase activity - - - 0.0000007086 59.0
HFD3_k127_4028274_24 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000001533 53.0
HFD3_k127_4028274_25 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000001582 49.0
HFD3_k127_4028274_3 S-adenosylhomocysteine deaminase activity - - - 9.666e-248 778.0
HFD3_k127_4028274_4 Zinc metalloprotease (Elastase) K01400,K01417,K20274 - 3.4.24.28 7.354e-240 773.0
HFD3_k127_4028274_5 Alpha-amylase C-terminal beta-sheet domain K01176 - 3.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006617 552.0
HFD3_k127_4028274_6 Esterase of the alpha-beta hydrolase superfamily K07001 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005897 508.0
HFD3_k127_4028274_7 Thermolysin metallopeptidase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008164 429.0
HFD3_k127_4028274_8 Uracil DNA glycosylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 360.0
HFD3_k127_4028274_9 Papain family cysteine protease - - - 0.00000000000000000000000000000000000000000000000002485 184.0
HFD3_k127_4031962_0 PFAM FAD dependent oxidoreductase K07137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 569.0
HFD3_k127_4031962_1 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 564.0
HFD3_k127_4031962_2 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008374 415.0
HFD3_k127_4031962_3 cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000001422 218.0
HFD3_k127_4031962_4 protein deglycation K03152,K05520,K12132 - 2.7.11.1,3.5.1.124 0.00000000000000000000000000000000000000000000001402 177.0
HFD3_k127_4031962_5 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000004063 176.0
HFD3_k127_4031962_6 - - - - 0.00000000000000000000000000000000000009067 159.0
HFD3_k127_4031962_7 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000021 124.0
HFD3_k127_4031962_8 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000005371 88.0
HFD3_k127_4031962_9 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0008944 51.0
HFD3_k127_4032892_0 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 338.0
HFD3_k127_4034901_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.666e-262 819.0
HFD3_k127_4034901_1 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000004494 221.0
HFD3_k127_4041468_0 Domains REC, sigma54 interaction, HTH8 K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 613.0
HFD3_k127_4041468_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006473 486.0
HFD3_k127_4041468_2 eight transmembrane protein EpsH - - - 0.0000000000000000000000000000000000000000000006147 177.0
HFD3_k127_4041468_3 transferase activity, transferring amino-acyl groups K15760,K18223 - 1.14.13.227,1.14.13.236 0.0000000000000000000000000000000000204 149.0
HFD3_k127_4041468_4 Domain of unknown function (DUF362) - - - 0.000000000000000000002144 101.0
HFD3_k127_4042326_0 Protein of unknown function (DUF401) K09133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 323.0
HFD3_k127_4042326_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 292.0
HFD3_k127_4042326_2 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000006706 191.0
HFD3_k127_4042326_3 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0000000000000000000000000000000000000000000000000009718 189.0
HFD3_k127_4042326_4 Single-strand binding protein family K03111 - - 0.00000000000000000000000000000000000000000000000001127 183.0
HFD3_k127_4042326_5 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000001352 117.0
HFD3_k127_4042326_6 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000001583 111.0
HFD3_k127_4042326_7 energy transducer activity K03832 - - 0.00000000000000001462 93.0
HFD3_k127_4046676_0 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000992 249.0
HFD3_k127_4046676_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000001759 240.0
HFD3_k127_4046676_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000002619 219.0
HFD3_k127_4046676_3 phosphorelay signal transduction system - - - 0.00000000000001381 81.0
HFD3_k127_4046676_4 Domain of unknown function (DUF3786) - - - 0.0000000005357 67.0
HFD3_k127_4046676_5 40-residue YVTN family beta-propeller repeat - - - 0.0000002343 58.0
HFD3_k127_4052405_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004455 356.0
HFD3_k127_4052405_2 - - - - 0.00000000000000000000000000000000000000000000005196 179.0
HFD3_k127_4052405_3 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000007 65.0
HFD3_k127_4052405_4 TIGRFAM decaheme c-type cytochrome, OmcA MtrC family - - - 0.0000002628 55.0
HFD3_k127_4071214_0 Belongs to the heme-copper respiratory oxidase family K00404,K15862 - 1.9.3.1 1.263e-253 788.0
HFD3_k127_4071214_1 PFAM cytochrome C oxidase mono-heme subunit FixO K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007928 346.0
HFD3_k127_4071214_2 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001154 264.0
HFD3_k127_4071214_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000001521 211.0
HFD3_k127_4071214_4 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.0000000000000000000000000000001864 127.0
HFD3_k127_4071214_5 N-terminal domain of cytochrome oxidase-cbb3, FixP - - - 0.00000000000000003649 82.0
HFD3_k127_4071214_6 AhpC/TSA family K03386 - 1.11.1.15 0.00000000000000004671 82.0
HFD3_k127_4077334_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 613.0
HFD3_k127_4077334_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 479.0
HFD3_k127_4077334_10 Vacuole effluxer Atg22 like K06902 - - 0.000000000000007323 76.0
HFD3_k127_4077334_11 Peroxisomal biogenesis factor 5 K13342,K20915 GO:0000038,GO:0000268,GO:0001764,GO:0002119,GO:0002164,GO:0003008,GO:0003674,GO:0005048,GO:0005052,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005778,GO:0005782,GO:0005794,GO:0005829,GO:0006082,GO:0006464,GO:0006605,GO:0006612,GO:0006625,GO:0006629,GO:0006631,GO:0006635,GO:0006807,GO:0006810,GO:0006886,GO:0006928,GO:0006996,GO:0007005,GO:0007006,GO:0007029,GO:0007031,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0008022,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009791,GO:0009987,GO:0010256,GO:0012505,GO:0015031,GO:0015833,GO:0015919,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016477,GO:0016558,GO:0016560,GO:0016561,GO:0016567,GO:0017038,GO:0019395,GO:0019538,GO:0019752,GO:0019899,GO:0021537,GO:0021543,GO:0021795,GO:0021885,GO:0021895,GO:0021953,GO:0021987,GO:0022008,GO:0022029,GO:0022607,GO:0030154,GO:0030182,GO:0030258,GO:0030900,GO:0031090,GO:0031267,GO:0031333,GO:0031903,GO:0031907,GO:0031974,GO:0032446,GO:0032459,GO:0032460,GO:0032462,GO:0032463,GO:0032501,GO:0032502,GO:0032787,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034440,GO:0034613,GO:0036211,GO:0040008,GO:0040011,GO:0040014,GO:0040018,GO:0042221,GO:0042277,GO:0042493,GO:0042579,GO:0042886,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043254,GO:0043412,GO:0043436,GO:0043574,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0044743,GO:0045046,GO:0045184,GO:0045927,GO:0046395,GO:0046907,GO:0047485,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048523,GO:0048638,GO:0048639,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0048870,GO:0050789,GO:0050793,GO:0050794,GO:0050877,GO:0050896,GO:0050905,GO:0051020,GO:0051094,GO:0051128,GO:0051129,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051259,GO:0051262,GO:0051641,GO:0051649,GO:0051674,GO:0055085,GO:0055114,GO:0060322,GO:0061024,GO:0065002,GO:0065003,GO:0065007,GO:0070013,GO:0070647,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071806,GO:0071840,GO:0072329,GO:0072347,GO:0072594,GO:0072657,GO:0072662,GO:0072663,GO:0090150,GO:0098588,GO:0098805,GO:1901090,GO:1901091,GO:1901093,GO:1901094,GO:1901564,GO:1901575 - 0.000003333 58.0
HFD3_k127_4077334_2 Trypsin K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007294 439.0
HFD3_k127_4077334_3 regulation of RNA biosynthetic process - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 341.0
HFD3_k127_4077334_4 Large family of predicted nucleotide-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 331.0
HFD3_k127_4077334_5 PFAM Stage II sporulation K06381 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009235 250.0
HFD3_k127_4077334_6 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000003515 228.0
HFD3_k127_4077334_7 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000002494 183.0
HFD3_k127_4077334_8 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000000000000000000000000000001036 177.0
HFD3_k127_4077334_9 PFAM aminotransferase, class I and II K00812 - 2.6.1.1 0.00000000000000001581 83.0
HFD3_k127_4092505_0 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001166 236.0
HFD3_k127_4092505_1 Protein of unknown function (DUF3175) - - - 0.000000000000000000000000000002472 123.0
HFD3_k127_4092505_2 protein histidine kinase activity K02484,K07636,K07651,K07769 - 2.7.13.3 0.0000000000000184 76.0
HFD3_k127_4092505_3 PFAM YHS domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.000001328 51.0
HFD3_k127_4092713_0 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004656 360.0
HFD3_k127_4092713_1 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005045 335.0
HFD3_k127_4092713_2 Histidine kinase K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 321.0
HFD3_k127_4092713_3 SMART Signal transduction response regulator, receiver region - - - 0.000000000000000000000000000000000000000000000000000000000001932 212.0
HFD3_k127_4092713_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000005625 169.0
HFD3_k127_4092713_5 response regulator, receiver - - - 0.00000000000000000000000000000000003146 142.0
HFD3_k127_4092713_6 PAS fold - - - 0.00000000000000006057 80.0
HFD3_k127_4092713_7 Response regulator, receiver - - - 0.000000004009 65.0
HFD3_k127_4092713_8 extracellular alpha-helical protein K06894 - - 0.0002582 46.0
HFD3_k127_4092713_9 penicillin-binding protein K05367 - 2.4.1.129 0.0003328 44.0
HFD3_k127_4093017_0 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007684 484.0
HFD3_k127_4093017_1 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000008102 237.0
HFD3_k127_4093017_2 Belongs to the HesB IscA family K13628 - - 0.00000000000000001009 87.0
HFD3_k127_4115120_0 COG1104 Cysteine sulfinate desulfinase cysteine desulfurase K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 497.0
HFD3_k127_4115120_1 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002922 270.0
HFD3_k127_4115120_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000000000000000000000000000000000000000000000002151 206.0
HFD3_k127_4115120_3 Fe-S iron-sulfur cluster assembly protein, NifU family K04488 - - 0.0000000000000000000000000000000000000000000000000000002477 197.0
HFD3_k127_4115120_4 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.000000000000000000000000000000000000000003987 159.0
HFD3_k127_4115120_5 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000001301 126.0
HFD3_k127_4115120_6 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000000000001288 104.0
HFD3_k127_4115120_7 Mechanosensitive ion channel K03442 - - 0.00000000000000000006785 94.0
HFD3_k127_4125212_1 Protein of unknown function (DUF1499) - - - 0.00000000000000000000000000000000003023 136.0
HFD3_k127_4125212_2 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000764 121.0
HFD3_k127_4125212_3 Integrase core domain - - - 0.0000000001082 65.0
HFD3_k127_4125212_4 - - - - 0.000005096 55.0
HFD3_k127_4125212_5 Winged helix-turn helix - - - 0.000006093 48.0
HFD3_k127_4129804_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 4.755e-245 770.0
HFD3_k127_4129804_1 ATP-dependent DNA helicase K03657 - 3.6.4.12 2.095e-213 685.0
HFD3_k127_4129804_10 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000000000003893 163.0
HFD3_k127_4129804_11 glucosamine-1-phosphate N-acetyltransferase activity K04042,K11528,K16203 GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030203,GO:0030260,GO:0033692,GO:0034637,GO:0034645,GO:0035635,GO:0040007,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000002458 157.0
HFD3_k127_4129804_12 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000004392 115.0
HFD3_k127_4129804_13 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.0000000000000000000007582 104.0
HFD3_k127_4129804_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 2.051e-209 661.0
HFD3_k127_4129804_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 2.502e-197 625.0
HFD3_k127_4129804_4 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 508.0
HFD3_k127_4129804_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 505.0
HFD3_k127_4129804_6 mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 335.0
HFD3_k127_4129804_7 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002146 276.0
HFD3_k127_4129804_8 PFAM Phosphatidic acid phosphatase type 2 haloperoxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002571 269.0
HFD3_k127_4129804_9 PFAM Glycosyl transferases group 1 K13057 - 2.4.1.245 0.000000000000000000000000000000000000000000000000000001722 195.0
HFD3_k127_413032_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1013.0
HFD3_k127_413032_1 Probable molybdopterin binding domain K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000753 257.0
HFD3_k127_413032_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000002186 214.0
HFD3_k127_413032_3 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000001183 185.0
HFD3_k127_413032_4 Mo-molybdopterin cofactor biosynthetic process - - - 0.000000000001482 68.0
HFD3_k127_4142369_0 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000273 289.0
HFD3_k127_4142369_1 - - - - 0.0000000000000002858 83.0
HFD3_k127_4142369_2 Late embryogenesis abundant protein - - - 0.000000000157 69.0
HFD3_k127_4154318_0 PFAM Type II secretion system protein E K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 332.0
HFD3_k127_4154318_1 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001212 260.0
HFD3_k127_4154318_2 Male sterility protein K01897 - 6.2.1.3 0.00000000000001158 77.0
HFD3_k127_4180624_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 3.116e-211 677.0
HFD3_k127_4180624_1 Elongation factor SelB winged helix 3 K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 572.0
HFD3_k127_4180624_2 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 471.0
HFD3_k127_4180624_3 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 437.0
HFD3_k127_4180624_4 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004205 277.0
HFD3_k127_4180624_5 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000002642 190.0
HFD3_k127_4180624_6 Uncharacterized protein conserved in archaea (DUF2180) - - - 0.000000000000000002806 87.0
HFD3_k127_4180624_7 Calcineurin-like phosphoesterase superfamily domain K03651 - 3.1.4.53 0.000000000000006841 86.0
HFD3_k127_4203848_0 PEP-utilising enzyme, N-terminal K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 589.0
HFD3_k127_4203848_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 361.0
HFD3_k127_4203848_2 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001374 279.0
HFD3_k127_4203848_3 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004693 283.0
HFD3_k127_4203848_4 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000001793 145.0
HFD3_k127_4203848_5 Phosphocarrier protein HPr K08485,K11189 - - 0.0000000000000000000001307 104.0
HFD3_k127_4203848_6 PTS system mannose/fructose/sorbose family IID component K02796 - - 0.000000000000002753 82.0
HFD3_k127_4203848_7 - - - - 0.000000008293 61.0
HFD3_k127_4203976_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 6.821e-231 741.0
HFD3_k127_4203976_1 ABC-type antimicrobial peptide transport system, permease component K02004 - - 2.243e-194 612.0
HFD3_k127_4203976_2 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007067 487.0
HFD3_k127_4203976_3 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 411.0
HFD3_k127_4203976_4 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 344.0
HFD3_k127_4203976_5 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000009054 251.0
HFD3_k127_4203976_6 Signal transduction histidine kinase, nitrogen specific, NtrB K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000005135 238.0
HFD3_k127_4203976_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000002067 100.0
HFD3_k127_4238861_0 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 389.0
HFD3_k127_4238861_1 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008165 382.0
HFD3_k127_4238861_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002038 281.0
HFD3_k127_4238861_3 Universal stress protein family K07090 - - 0.000000000000000000003545 98.0
HFD3_k127_4238861_4 YtxH-like protein - - - 0.00000001116 63.0
HFD3_k127_4238861_5 Evidence 4 Homologs of previously reported genes of - - - 0.0000001736 60.0
HFD3_k127_4284255_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 6.657e-217 676.0
HFD3_k127_4284255_1 NAD(P)H-binding K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 470.0
HFD3_k127_4284255_2 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001584 256.0
HFD3_k127_4284255_3 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000000000000000000000000000000000003922 200.0
HFD3_k127_4284255_4 peptidyl-tyrosine sulfation - - - 0.00000009556 58.0
HFD3_k127_4325401_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 2.425e-211 666.0
HFD3_k127_4325401_1 NUBPL iron-transfer P-loop NTPase K04562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007167 427.0
HFD3_k127_4325401_2 serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009038 321.0
HFD3_k127_4325401_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000005435 240.0
HFD3_k127_4325401_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000007007 193.0
HFD3_k127_4325401_5 Universal stress protein family - - - 0.00000000000000000001939 97.0
HFD3_k127_4325401_6 PBS lyase HEAT-like repeat - - - 0.00000000000006968 82.0
HFD3_k127_4337605_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009025 514.0
HFD3_k127_4337605_1 RNA pseudouridylate synthase K06177,K06180 - 5.4.99.23,5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000001304 267.0
HFD3_k127_4337605_3 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain - - - 0.00000000000000000002993 91.0
HFD3_k127_4427421_0 PBP superfamily domain K03750,K07219 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 512.0
HFD3_k127_4427421_1 TolB amino-terminal domain K03641 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019534,GO:0019904,GO:0022857,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 359.0
HFD3_k127_4427421_2 MotA/TolQ/ExbB proton channel family K03561,K03562 - - 0.00000000000000000000000000000000000000000000002255 179.0
HFD3_k127_4427421_3 Biopolymer transport protein ExbD/TolR K03560 - - 0.0000000000000000000000000000000000002728 145.0
HFD3_k127_4427421_4 TonB C terminal K03832 - - 0.000001285 59.0
HFD3_k127_4435929_0 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000003767 242.0
HFD3_k127_4435929_1 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000001496 194.0
HFD3_k127_4435929_2 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000000000000001717 195.0
HFD3_k127_4435929_3 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000000000001901 91.0
HFD3_k127_4435929_4 - - - - 0.0000000000000002747 84.0
HFD3_k127_4472383_0 Elongator protein 3, MiaB family, Radical SAM - - - 5.636e-208 658.0
HFD3_k127_4472383_1 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 282.0
HFD3_k127_4472383_2 DNA-3-methyladenine glycosylase I K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001677 271.0
HFD3_k127_4472383_3 Shikimate kinase K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000000000000002294 210.0
HFD3_k127_4473261_0 trisaccharide binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 484.0
HFD3_k127_4473261_1 PFAM ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000001445 136.0
HFD3_k127_4473261_2 helix_turn_helix, Lux Regulon K14979 - - 0.000000001012 70.0
HFD3_k127_448047_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 434.0
HFD3_k127_448047_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002551 255.0
HFD3_k127_448047_2 Histidine kinase-like ATPases - - - 0.000000000000006868 78.0
HFD3_k127_448047_3 NlpC/P60 family K20742 - 3.4.14.13 0.000000000000007523 88.0
HFD3_k127_4500161_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1238.0
HFD3_k127_4500161_1 Alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004462 448.0
HFD3_k127_4500161_2 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000571 400.0
HFD3_k127_4546340_0 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007925 522.0
HFD3_k127_4546340_1 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 445.0
HFD3_k127_4546340_3 Protein of unknown function (DUF3568) - - - 0.000000009773 62.0
HFD3_k127_4600295_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 579.0
HFD3_k127_4600295_1 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000408 287.0
HFD3_k127_4600295_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001213 276.0
HFD3_k127_4600295_3 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005561 252.0
HFD3_k127_4600295_4 Methylpurine-DNA glycosylase (MPG) K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000002314 238.0
HFD3_k127_4600295_5 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000002033 224.0
HFD3_k127_4600295_7 Evidence 5 No homology to any previously reported sequences K07156,K07245,K14166 - - 0.00000000000000000000000000000000002677 138.0
HFD3_k127_4600295_8 copper resistance K07245,K14166 - - 0.00000000000000000000000000000002228 145.0
HFD3_k127_4600295_9 Membrane - - - 0.00000000000000000000000008144 124.0
HFD3_k127_4675356_0 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 527.0
HFD3_k127_4675356_1 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 347.0
HFD3_k127_4675356_2 Transposase IS116/IS110/IS902 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 321.0
HFD3_k127_4675356_3 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000105 275.0
HFD3_k127_4675356_4 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000001662 240.0
HFD3_k127_4675356_5 Pyruvate phosphate dikinase - - - 0.000000000000000000000000000000000000000000000000000000000000000397 227.0
HFD3_k127_4675356_6 AMP binding - - - 0.0000000000000000000000000000000000000000000000006402 185.0
HFD3_k127_4675356_7 - - - - 0.0000000000000000000000000000000000002147 150.0
HFD3_k127_4675356_8 response regulator K07685,K07688 - - 0.00002071 57.0
HFD3_k127_4689395_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006151 554.0
HFD3_k127_4689395_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 390.0
HFD3_k127_4689395_2 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004046 253.0
HFD3_k127_4689395_3 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001373 256.0
HFD3_k127_4689395_4 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.000000000000000000000000000000000000000000000001706 183.0
HFD3_k127_4689395_5 cyclic nucleotide binding K00384,K01420 - 1.8.1.9 0.0000000000000000000000000002157 119.0
HFD3_k127_4689395_6 Essential cell division protein K03589 - - 0.0000000000000000000004796 106.0
HFD3_k127_4689395_7 TIGRFAM cysteine K12339 - 2.5.1.47 0.00000000000000008147 81.0
HFD3_k127_4689395_8 Cell wall formation K01921 - 6.3.2.4 0.000000001158 59.0
HFD3_k127_4712493_0 Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008724 466.0
HFD3_k127_4712493_1 Pyridoxal-phosphate dependent enzyme K01738,K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 417.0
HFD3_k127_4712493_2 Nitrous oxide-stimulated promoter - - - 0.0000000000000000000000000000000001227 137.0
HFD3_k127_4717375_0 Proton-conducting membrane transporter - - - 2.38e-232 736.0
HFD3_k127_4717375_1 Proton-conducting membrane transporter K12141 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004074 510.0
HFD3_k127_4717375_2 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 410.0
HFD3_k127_4717375_3 Hydrogenase 4 membrane K12140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005635 255.0
HFD3_k127_4717375_4 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000002767 177.0
HFD3_k127_4717375_5 Membrane - - - 0.000000000000002503 78.0
HFD3_k127_4721991_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008267 448.0
HFD3_k127_4721991_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000004169 219.0
HFD3_k127_4721991_2 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000007324 207.0
HFD3_k127_4731281_0 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 287.0
HFD3_k127_4731281_1 COG3547 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000001349 166.0
HFD3_k127_4731281_2 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000003602 142.0
HFD3_k127_4731281_3 - - - - 0.000000000000000000000000000000000001803 141.0
HFD3_k127_4731281_4 short-chain dehydrogenase - - - 0.000000000003194 73.0
HFD3_k127_4748386_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1138.0
HFD3_k127_4748386_1 polyribonucleotide nucleotidyltransferase activity K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 8.902e-257 809.0
HFD3_k127_4748386_10 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K16363 - 3.5.1.108,4.2.1.59 0.0000000000000000000000000000000000000000000000000000008375 196.0
HFD3_k127_4748386_11 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000001374 195.0
HFD3_k127_4748386_12 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000002245 127.0
HFD3_k127_4748386_13 domain, Protein K02674 - - 0.00000000000000000000000000009969 124.0
HFD3_k127_4748386_14 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K06142 - - 0.00000000007852 70.0
HFD3_k127_4748386_15 phytoene K01854 - 5.4.99.9 0.00004533 55.0
HFD3_k127_4748386_2 Surface antigen K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000957 557.0
HFD3_k127_4748386_3 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 413.0
HFD3_k127_4748386_4 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006091 333.0
HFD3_k127_4748386_5 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 324.0
HFD3_k127_4748386_6 Protein of unknown function (DUF1009) K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 317.0
HFD3_k127_4748386_7 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 315.0
HFD3_k127_4748386_8 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 308.0
HFD3_k127_4748386_9 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 293.0
HFD3_k127_4748605_0 HlyD family secretion protein K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009495 473.0
HFD3_k127_4748605_1 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 351.0
HFD3_k127_4748605_2 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564 - 0.00000000000000000000000000000000000000000000000000002575 191.0
HFD3_k127_4748605_4 Unextendable partial coding region - - - 0.00000000000000005817 81.0
HFD3_k127_4748605_5 - - - - 0.000000004842 61.0
HFD3_k127_4755607_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 570.0
HFD3_k127_4755607_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006548 430.0
HFD3_k127_4755607_12 - - - - 0.0005003 45.0
HFD3_k127_4755607_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002718 244.0
HFD3_k127_4755607_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000006635 212.0
HFD3_k127_4755607_4 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) - - - 0.00000000000000000000000000000000000000000000000001994 185.0
HFD3_k127_4755607_5 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000005046 128.0
HFD3_k127_4755607_6 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.00000000000000000000000002855 115.0
HFD3_k127_4755607_7 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.00000000000000000002319 93.0
HFD3_k127_4755607_8 peptidyl-tyrosine sulfation - - - 0.00000000000001448 84.0
HFD3_k127_4758922_0 Cache domain - - - 1.597e-249 782.0
HFD3_k127_4758922_1 Na dependent nucleoside transporter K03317 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 511.0
HFD3_k127_4758922_10 Protein tyrosine kinase - - - 0.00008953 53.0
HFD3_k127_4758922_2 Unusual protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 321.0
HFD3_k127_4758922_3 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000003862 261.0
HFD3_k127_4758922_4 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000002556 126.0
HFD3_k127_4758922_5 regulation of translation K03530 - - 0.00000000000000000000000000004852 119.0
HFD3_k127_4758922_6 SMART Cold shock protein K03704 - - 0.00000000000000000000000045 105.0
HFD3_k127_4758922_7 PFAM glycoside hydrolase, family 13 domain protein - - - 0.00000000000000000006758 93.0
HFD3_k127_4758922_9 reverse transcriptase K00986 - 2.7.7.49 0.00003017 46.0
HFD3_k127_4759753_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007696 447.0
HFD3_k127_4759753_1 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 398.0
HFD3_k127_4759753_10 CBS domain - - - 0.00000000000006224 78.0
HFD3_k127_4759753_11 formate dehydrogenase K03620 - - 0.0000001259 62.0
HFD3_k127_4759753_2 Cytochrome b subunit of the bc complex K15879 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 369.0
HFD3_k127_4759753_3 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 345.0
HFD3_k127_4759753_4 PFAM Roadblock LC7 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000114 222.0
HFD3_k127_4759753_5 PFAM Sodium hydrogen exchanger family K03455 - - 0.00000000000000000000000000000000000000001218 158.0
HFD3_k127_4759753_6 part of a sulfur-relay system K11179 - - 0.0000000000000000000000000000000005088 134.0
HFD3_k127_4759753_7 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000001515 129.0
HFD3_k127_4759753_8 Transposase IS200 like K07491 - - 0.000000000000000000000002013 107.0
HFD3_k127_4759753_9 formate dehydrogenase K03620 - - 0.0000000000000000000002992 107.0
HFD3_k127_4762723_0 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008268 404.0
HFD3_k127_4762723_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009613 319.0
HFD3_k127_4762723_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 308.0
HFD3_k127_4762723_3 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000001879 132.0
HFD3_k127_4762723_4 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000000000001306 93.0
HFD3_k127_4762723_5 general secretion pathway protein - - - 0.0000005554 51.0
HFD3_k127_4762723_9 - - - - 0.0000229 48.0
HFD3_k127_4768145_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 507.0
HFD3_k127_4768145_1 TIGRFAM riboflavin biosynthesis protein RibF K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 302.0
HFD3_k127_4768145_2 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000005568 149.0
HFD3_k127_4768145_3 CbiX - - - 0.0000000000000000001225 94.0
HFD3_k127_4768145_4 - - - - 0.0000004239 52.0
HFD3_k127_4781611_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 536.0
HFD3_k127_4781611_1 carbonate dehydratase activity K01674 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001882 278.0
HFD3_k127_4781611_2 Cysteine rich repeat - - - 0.0000000000000000000000000000000000000000000000003762 180.0
HFD3_k127_4781611_3 Cysteine rich repeat - - - 0.00000000000000000000000000000000000000000000002524 173.0
HFD3_k127_4781611_4 PFAM OmpA MotB domain protein K02557 - - 0.00000000000000000000000000000000000000001521 165.0
HFD3_k127_4781611_5 Outer membrane protein beta-barrel domain - - - 0.00000000000000000000000000000000000000005668 162.0
HFD3_k127_4781611_6 Outer membrane protein beta-barrel domain - - - 0.0000000000000000000000000000000007914 139.0
HFD3_k127_4781611_7 - - - - 0.00000000000000000000000006594 114.0
HFD3_k127_4781611_8 Antibiotic biosynthesis monooxygenase K01056 GO:0003674,GO:0003824 3.1.1.29 0.0000000000000000000005622 100.0
HFD3_k127_4781611_9 Protein of unknown function K09800 - - 0.0000000005948 70.0
HFD3_k127_4786067_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 361.0
HFD3_k127_4786067_1 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 304.0
HFD3_k127_4786067_2 ribonuclease BN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003397 271.0
HFD3_k127_4786067_3 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000688 241.0
HFD3_k127_4786067_4 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000001541 217.0
HFD3_k127_4786067_5 PFAM HNH endonuclease - - - 0.000000000000000000000000000000000000000000000001339 178.0
HFD3_k127_4794950_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 528.0
HFD3_k127_4794950_1 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 520.0
HFD3_k127_4794950_2 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 413.0
HFD3_k127_4794950_3 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000245 263.0
HFD3_k127_4794950_4 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000005522 245.0
HFD3_k127_4794950_5 component of anaerobic - - - 0.00000000000000000000000000000000000000001407 160.0
HFD3_k127_4794950_6 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.000000000000000000000005142 115.0
HFD3_k127_4810105_0 proteolysis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 306.0
HFD3_k127_4810105_1 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059,K07124 - 1.1.1.100 0.00000000000000000000003951 105.0
HFD3_k127_4849462_0 PFAM Cytochrome b b6 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 558.0
HFD3_k127_4849462_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 497.0
HFD3_k127_4849462_2 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 301.0
HFD3_k127_4849462_3 Cytochrome c K00373,K00405,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.00000000000000000000000000000000000000000001275 171.0
HFD3_k127_4849462_4 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000000000002842 137.0
HFD3_k127_4849462_5 Two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.00000000000000000000000002141 112.0
HFD3_k127_4883395_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 1.539e-271 849.0
HFD3_k127_4903568_0 L,D-transpeptidase catalytic domain K16291 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006096 336.0
HFD3_k127_4903568_1 CsbD-like - - - 0.000000000000000000000006778 102.0
HFD3_k127_4903568_2 - - - - 0.0000000000000008546 77.0
HFD3_k127_4925746_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 5.201e-250 782.0
HFD3_k127_4925746_1 PFAM NAD-dependent epimerase dehydratase K08678 - 4.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 512.0
HFD3_k127_4925746_2 SIS domain K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 406.0
HFD3_k127_4925746_3 PFAM DAHP synthetase I KDSA K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 369.0
HFD3_k127_4925746_4 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 294.0
HFD3_k127_4925746_5 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000002175 200.0
HFD3_k127_4925746_6 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000007589 195.0
HFD3_k127_4925746_7 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000001963 182.0
HFD3_k127_4925746_8 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000008324 169.0
HFD3_k127_4936924_0 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 1.964e-214 678.0
HFD3_k127_4936924_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002949 446.0
HFD3_k127_4936924_2 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782 452.0
HFD3_k127_4936924_3 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 319.0
HFD3_k127_4957430_0 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K05568 - - 3.95e-196 631.0
HFD3_k127_4957430_1 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000002808 64.0
HFD3_k127_4970936_0 TIGRFAM type IV-A pilus assembly ATPase PilB K02652 - - 4.231e-196 629.0
HFD3_k127_4970936_1 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 548.0
HFD3_k127_4970936_2 Type II secretion system (T2SS), protein F K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 373.0
HFD3_k127_4970936_3 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 307.0
HFD3_k127_4970936_4 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000149 233.0
HFD3_k127_4970936_5 Protein of unknown function (DUF512) - - - 0.00000000000000000000000000000000000000000007596 166.0
HFD3_k127_4972902_0 Conserved carboxylase domain K01958 - 6.4.1.1 0.0 1086.0
HFD3_k127_4972902_1 acetyl-CoA carboxylase, biotin carboxylase K01965 - 6.4.1.3 4.047e-243 758.0
HFD3_k127_4972902_2 membrane transporter protein K07090 - - 4.39e-204 642.0
HFD3_k127_4972902_3 phosphorelay signal transduction system K02584,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 472.0
HFD3_k127_4972902_4 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007813 401.0
HFD3_k127_4972902_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000515 276.0
HFD3_k127_4972902_6 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000002904 233.0
HFD3_k127_4972902_7 Universal stress protein family K07090 - - 0.00000000000000000000000000000000000000000000000000000000003095 216.0
HFD3_k127_4972902_8 DNA-binding transcription factor activity K03710 - - 0.00000000000000000000000000000001082 136.0
HFD3_k127_4974055_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 4.024e-265 827.0
HFD3_k127_4974055_1 Dehydratase family K01687 - 4.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 398.0
HFD3_k127_4987954_0 PFAM Metal-dependent phosphohydrolase, HD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 434.0
HFD3_k127_4987954_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 424.0
HFD3_k127_4987954_2 AcrB/AcrD/AcrF family - - - 0.0000000000000000000000000000000000000000000000000007836 188.0
HFD3_k127_4987954_3 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000008973 176.0
HFD3_k127_5001069_0 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 306.0
HFD3_k127_5001069_1 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000003795 196.0
HFD3_k127_5001069_2 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.000000000000000000000000000000000000003922 151.0
HFD3_k127_5001069_3 PTS system fructose IIA component K02793,K02794,K02821 - 2.7.1.191,2.7.1.194 0.00000000000000000000000000004459 121.0
HFD3_k127_5001069_4 PTS system mannose/fructose/sorbose family IID component K02796 - - 0.0000000000000000000000000004315 117.0
HFD3_k127_5001069_5 PTS system sorbose subfamily IIB component K02794 - 2.7.1.191 0.000000000000000000000000001468 117.0
HFD3_k127_5001069_6 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000008266 86.0
HFD3_k127_5001069_7 PTS system sorbose-specific iic component K02795 - - 0.000000000000000005836 93.0
HFD3_k127_5003227_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 333.0
HFD3_k127_5003227_1 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007128 250.0
HFD3_k127_5003227_2 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000000000000000000000009163 196.0
HFD3_k127_5003227_3 cyclic nucleotide binding K10914 - - 0.0000000000000000000000268 105.0
HFD3_k127_5003227_4 COG0675 Transposase and inactivated derivatives K07496 - - 0.000003592 52.0
HFD3_k127_5026556_0 PFAM Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 499.0
HFD3_k127_5026556_1 PFAM 4Fe-4S K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005534 427.0
HFD3_k127_5026556_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006951 346.0
HFD3_k127_5026556_3 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000004627 217.0
HFD3_k127_5026556_4 Cytochrome c - - - 0.0000000000000000000000000000000000000000000001872 169.0
HFD3_k127_5026556_5 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000000000000000001174 152.0
HFD3_k127_5026556_6 PFAM Rieske 2Fe-2S K02636 - 1.10.9.1 0.000000000000000000000000196 110.0
HFD3_k127_5026556_7 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000004108 104.0
HFD3_k127_5026556_8 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000001109 98.0
HFD3_k127_5026556_9 PFAM Beta-propeller repeat - - - 0.000001809 59.0
HFD3_k127_5045664_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 9e-323 1009.0
HFD3_k127_5045664_1 ABC1 family K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005527 468.0
HFD3_k127_5045664_2 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005382 286.0
HFD3_k127_5045664_3 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002572 255.0
HFD3_k127_5045664_4 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000001444 213.0
HFD3_k127_5045664_5 - - - - 0.000000000008116 70.0
HFD3_k127_5065488_0 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 0.0 1036.0
HFD3_k127_5065488_1 Molecular chaperone. Has ATPase activity K04079 - - 1.282e-283 883.0
HFD3_k127_5065488_10 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000003674 179.0
HFD3_k127_5065488_11 EVE domain - - - 0.0000000000000000000000000000000000001684 146.0
HFD3_k127_5065488_12 peptidyl-prolyl cis-trans isomerase activity K03769,K07533 - 5.2.1.8 0.0000000000000000000000000000005452 134.0
HFD3_k127_5065488_13 - - - - 0.0000000000000000000000000000006629 124.0
HFD3_k127_5065488_14 - - - - 0.0000000000000000000000006203 113.0
HFD3_k127_5065488_15 UV-endonuclease UvdE - - - 0.00000000000000000000001911 102.0
HFD3_k127_5065488_16 Uncharacterized conserved protein (DUF2196) - - - 0.0000000000000000000001428 98.0
HFD3_k127_5065488_17 amine dehydrogenase activity - - - 0.0000000000000000001054 104.0
HFD3_k127_5065488_18 PFAM PKD domain - - - 0.000000000000000005211 99.0
HFD3_k127_5065488_19 - - - - 0.000000000000001207 79.0
HFD3_k127_5065488_2 TRCF K03723 - - 2.558e-279 899.0
HFD3_k127_5065488_20 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.000000001609 68.0
HFD3_k127_5065488_21 PFAM response regulator receiver - - - 0.000007923 49.0
HFD3_k127_5065488_3 Histone deacetylase domain K04768 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 400.0
HFD3_k127_5065488_4 Methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 392.0
HFD3_k127_5065488_5 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 346.0
HFD3_k127_5065488_6 beta-keto acid cleavage enzyme K18013 - 2.3.1.247 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 325.0
HFD3_k127_5065488_7 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000593 216.0
HFD3_k127_5065488_8 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.000000000000000000000000000000000000000000000000000000005126 203.0
HFD3_k127_5065488_9 SurA N-terminal domain K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000004049 190.0
HFD3_k127_5109808_0 Domain of unknown function (DUF3416) K16147 - 2.4.99.16 2.702e-258 813.0
HFD3_k127_5109808_1 Alkaline and neutral invertase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 553.0
HFD3_k127_5109808_2 PFAM Glycosyl transferases group 1 K13057 - 2.4.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 463.0
HFD3_k127_5109808_3 SMART alpha amylase, catalytic sub domain K01187,K05343 - 3.2.1.1,3.2.1.20,5.4.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 297.0
HFD3_k127_5121725_0 CoA enzyme activase uncharacterised domain (DUF2229) - - - 3.427e-287 897.0
HFD3_k127_5121725_1 Glyoxalase-like domain K06996 - - 0.000000000000000000000000000000000000003725 149.0
HFD3_k127_5206331_0 TPR repeat - - - 1.591e-300 943.0
HFD3_k127_5206331_1 polysaccharide deacetylase K11931,K21478 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016787,GO:0016810,GO:0043170,GO:0043412,GO:0071704,GO:0098732 - 0.000000000000000000000000000000000000000000000000000000000000446 220.0
HFD3_k127_5206331_2 Glycosyl transferase family 21 - - - 0.00000000000000000000000000009019 117.0
HFD3_k127_5208907_0 LysM domain K16291 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 307.0
HFD3_k127_5208907_1 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000003435 249.0
HFD3_k127_5208907_2 PFAM MgtC SapB transporter K07507 - - 0.00000000000000000000000000000000000000000000000000000000000000001203 232.0
HFD3_k127_5208907_3 part of a sulfur-relay system K11179 - - 0.000000000000000000000000000000003389 131.0
HFD3_k127_5208907_4 Geranylgeranyltransferase II beta subunit Ptb1 K05956 GO:0003674,GO:0003824,GO:0004659,GO:0004661,GO:0004663,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005968,GO:0006464,GO:0006605,GO:0006612,GO:0006807,GO:0006810,GO:0006886,GO:0006888,GO:0008104,GO:0008150,GO:0008152,GO:0008270,GO:0008318,GO:0009987,GO:0015031,GO:0015833,GO:0016192,GO:0016740,GO:0016765,GO:0017016,GO:0017137,GO:0018342,GO:0018344,GO:0019538,GO:0019899,GO:0031267,GO:0032991,GO:0033036,GO:0034613,GO:0036211,GO:0042886,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046872,GO:0046907,GO:0046914,GO:0048193,GO:0051020,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0072657,GO:0072659,GO:0090150,GO:0097354,GO:0140096,GO:1901564,GO:1902494,GO:1990234,GO:1990778 2.5.1.60 0.0000000000000002079 90.0
HFD3_k127_5208907_5 Domain of unknown function (DUF4382) - - - 0.0000000004938 63.0
HFD3_k127_5227496_0 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008475 279.0
HFD3_k127_5227496_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000001649 258.0
HFD3_k127_5227496_2 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000000000000000012 136.0
HFD3_k127_5227496_3 acr, cog1993 K09137 - - 0.00000000000000000000001723 103.0
HFD3_k127_5227496_4 phosphatidate phosphatase activity K01096,K19302 - 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.000000000000000000002768 101.0
HFD3_k127_5231244_0 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005477 464.0
HFD3_k127_5231244_1 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001183 269.0
HFD3_k127_5231244_2 PFAM NADH Ubiquinone - - - 0.000000000000000000000000000000000000000000000000000000000000000000001844 239.0
HFD3_k127_5231244_3 - - - - 0.0000000000000000000000000000000000000000000000000000000001203 208.0
HFD3_k127_5231244_4 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.00000000005894 65.0
HFD3_k127_52441_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 1.13e-205 653.0
HFD3_k127_52441_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601,K03797 - 3.1.11.6,3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006775 403.0
HFD3_k127_52441_2 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000002626 220.0
HFD3_k127_52441_3 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000004542 159.0
HFD3_k127_52441_4 TIGRFAM metallophosphoesterase, MG_246 BB_0505 family K09769 - - 0.000000000000000000000000000000000001927 139.0
HFD3_k127_52441_6 PBS lyase HEAT-like repeat - - - 0.000000000000000005354 99.0
HFD3_k127_5333912_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1106.0
HFD3_k127_5333912_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008947 420.0
HFD3_k127_5333912_2 4Fe-4S ferredoxin K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 296.0
HFD3_k127_5333912_3 Polysulfide reductase - - - 0.000000000000000000000000000000000000000000000000000001762 202.0
HFD3_k127_5333912_4 Protein involved in formate dehydrogenase formation K02380 - - 0.00000000000000000000000000000000001829 147.0
HFD3_k127_5333912_5 Cupredoxin-like domain - - - 0.00000000000000000000000008463 111.0
HFD3_k127_5333912_6 PFAM Hemerythrin HHE cation binding domain - - - 0.0000000000000008905 78.0
HFD3_k127_5336908_0 Alginate export - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 308.0
HFD3_k127_5336908_1 PFAM Amino acid-binding ACT - - - 0.00000000000000000000000000000000000000000000000000004221 190.0
HFD3_k127_5336908_2 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000001234 128.0
HFD3_k127_5336908_3 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000001269 56.0
HFD3_k127_5442070_0 Protein of unknown function (DUF1254) - - - 4.704e-268 831.0
HFD3_k127_5442070_1 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 341.0
HFD3_k127_5442070_2 Protein involved in outer membrane biogenesis - - - 0.00000000000000000000000000000000000000000003263 169.0
HFD3_k127_5442070_3 PFAM Methyltransferase type 11 - - - 0.00000000000000000000107 97.0
HFD3_k127_5442070_4 START domain - - - 0.0000000000006678 78.0
HFD3_k127_5442070_5 cellulase activity - - - 0.00000000003015 77.0
HFD3_k127_5445541_0 Carbamoyl-phosphate synthetase large chain domain protein K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 1.478e-195 618.0
HFD3_k127_5445541_1 PFAM natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006839 571.0
HFD3_k127_5445541_10 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000001089 232.0
HFD3_k127_5445541_11 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000001801 195.0
HFD3_k127_5445541_12 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000001224 184.0
HFD3_k127_5445541_13 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000003043 181.0
HFD3_k127_5445541_14 Acetyl-CoA carboxylase, biotin carboxyl carrier protein K01571,K01960 - 4.1.1.3,6.4.1.1 0.0000000000000000000000000000000000000001211 156.0
HFD3_k127_5445541_15 Belongs to the UPF0296 family K09777 - - 0.0000000000000000000000000151 111.0
HFD3_k127_5445541_16 Roadblock/LC7 domain - - - 0.000000000000000000000000271 108.0
HFD3_k127_5445541_17 Domain of unknown function (DUF1858) - - - 0.0000000000000000006473 88.0
HFD3_k127_5445541_18 tigr00255 - - - 0.00000000000000002089 82.0
HFD3_k127_5445541_19 sodium-dependent phosphate transmembrane transporter activity - - - 0.0000000000000003354 86.0
HFD3_k127_5445541_2 MgtE intracellular N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 427.0
HFD3_k127_5445541_20 belongs to the thioredoxin family K14949,K20543 - 2.7.11.1 0.0000000000000129 87.0
HFD3_k127_5445541_21 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000009795 59.0
HFD3_k127_5445541_22 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000002377 54.0
HFD3_k127_5445541_3 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 415.0
HFD3_k127_5445541_4 Receptor family ligand binding region K01999 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0070728,GO:0071702,GO:0071705 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 377.0
HFD3_k127_5445541_5 Branched-chain amino acid transport system / permease component K01997 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 357.0
HFD3_k127_5445541_6 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 316.0
HFD3_k127_5445541_7 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 300.0
HFD3_k127_5445541_8 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005522 270.0
HFD3_k127_5445541_9 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000005939 253.0
HFD3_k127_5447419_0 Alcohol dehydrogenase GroES-like domain K00008,K00148,K18369 - 1.1.1.14,1.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 578.0
HFD3_k127_5447419_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 501.0
HFD3_k127_5447419_10 - - - - 0.000000000000000000000000000000000000000000009934 169.0
HFD3_k127_5447419_11 SnoaL-like domain - - - 0.00000000000000000000000000000000000000004076 155.0
HFD3_k127_5447419_13 - - - - 0.000000000000000003099 89.0
HFD3_k127_5447419_14 heme oxygenase (decyclizing) activity - - - 0.0000000000000001724 83.0
HFD3_k127_5447419_15 Integral membrane protein TerC family K05794 - - 0.00000000000001752 76.0
HFD3_k127_5447419_16 domain, Protein - - - 0.0000000000001436 76.0
HFD3_k127_5447419_17 response regulator - - - 0.00001208 48.0
HFD3_k127_5447419_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 446.0
HFD3_k127_5447419_3 Histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 430.0
HFD3_k127_5447419_4 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008393 398.0
HFD3_k127_5447419_5 Transcriptional regulator sugar kinase K00886 - 2.7.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 284.0
HFD3_k127_5447419_6 SOS response associated peptidase (SRAP) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006219 254.0
HFD3_k127_5447419_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008801 244.0
HFD3_k127_5447419_8 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000006319 216.0
HFD3_k127_5447419_9 Peptidase S24-like K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000003608 203.0
HFD3_k127_5461793_0 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 498.0
HFD3_k127_5461793_1 NADPH:quinone reductase activity K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007076 415.0
HFD3_k127_5461793_2 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 296.0
HFD3_k127_5461793_3 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000002564 234.0
HFD3_k127_5461793_4 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000005952 222.0
HFD3_k127_5461793_5 Probable transposase - - - 0.0000000000000001468 83.0
HFD3_k127_5476705_0 PFAM S-adenosylmethionine synthetase (MAT) K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 593.0
HFD3_k127_5476705_1 Transcriptional regulatory protein, C terminal K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008556 295.0
HFD3_k127_5476705_2 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000006182 144.0
HFD3_k127_5480636_0 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001036 286.0
HFD3_k127_5480636_1 Iron-sulfur cluster-binding domain K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001642 281.0
HFD3_k127_5480636_2 HAD-superfamily hydrolase, subfamily IA, variant 3 K01091 - 3.1.3.18 0.000000000000000000000000000000000000000002037 164.0
HFD3_k127_5482691_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 2.549e-203 639.0
HFD3_k127_5482691_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003947 591.0
HFD3_k127_5482691_2 3-isopropylmalate dehydrogenase activity K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 549.0
HFD3_k127_5482691_3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 484.0
HFD3_k127_5482691_4 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004948 362.0
HFD3_k127_5482691_5 PFAM inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 287.0
HFD3_k127_5482691_6 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000001405 263.0
HFD3_k127_5482691_7 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000000000000000045 165.0
HFD3_k127_5482691_8 - - - - 0.00000004619 60.0
HFD3_k127_5482691_9 Fic/DOC family - - - 0.0001601 48.0
HFD3_k127_5493834_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 8.128e-258 810.0
HFD3_k127_5493834_1 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 490.0
HFD3_k127_5493834_10 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000008932 132.0
HFD3_k127_5493834_11 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0000000000000000000000003117 105.0
HFD3_k127_5493834_12 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.00000000000000000000009264 111.0
HFD3_k127_5493834_13 - - - - 0.0000000000000000000008614 99.0
HFD3_k127_5493834_14 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.000000000000001629 81.0
HFD3_k127_5493834_15 GTP-binding protein TypA K06207 - - 0.00000008585 54.0
HFD3_k127_5493834_16 - - - - 0.0001799 49.0
HFD3_k127_5493834_2 PHB de-polymerase C-terminus K03821 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008679 440.0
HFD3_k127_5493834_3 spermidine synthase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 442.0
HFD3_k127_5493834_4 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 327.0
HFD3_k127_5493834_5 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K02297 - 1.10.3.10,1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 325.0
HFD3_k127_5493834_6 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002521 283.0
HFD3_k127_5493834_7 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000004056 224.0
HFD3_k127_5493834_8 molybdopterin cofactor binding K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000007702 211.0
HFD3_k127_5493834_9 Nodulation protein S (NodS) - - - 0.0000000000000000000000000000000000000000000004276 175.0
HFD3_k127_55022_0 Belongs to the PstS family K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 463.0
HFD3_k127_55022_1 His Kinase A (phosphoacceptor) domain K02484,K07636,K07768 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 364.0
HFD3_k127_55022_2 DsrC like protein K11179 - - 0.000000000000000000000000000000002672 132.0
HFD3_k127_55022_3 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000005864 80.0
HFD3_k127_55022_4 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000008014 57.0
HFD3_k127_5509353_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 7.844e-239 773.0
HFD3_k127_5509353_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 575.0
HFD3_k127_5509353_10 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000004817 145.0
HFD3_k127_5509353_11 Peptidase_C39 like family - - - 0.00000000000000000000000000006163 123.0
HFD3_k127_5509353_12 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000001166 102.0
HFD3_k127_5509353_13 Tetratricopeptide repeat - - - 0.000000000000000000006562 101.0
HFD3_k127_5509353_14 S4 domain protein - - - 0.0000000000000000004385 89.0
HFD3_k127_5509353_15 - - - - 0.00000000000000009703 86.0
HFD3_k127_5509353_16 - - - - 0.00000000000003973 78.0
HFD3_k127_5509353_17 sigma factor antagonist activity K04757 - 2.7.11.1 0.000000000005115 79.0
HFD3_k127_5509353_18 Belongs to the glycosyl hydrolase 26 family - - - 0.000000002789 64.0
HFD3_k127_5509353_19 CpXC protein - - - 0.000001296 59.0
HFD3_k127_5509353_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 353.0
HFD3_k127_5509353_3 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 341.0
HFD3_k127_5509353_4 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 334.0
HFD3_k127_5509353_5 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006492 297.0
HFD3_k127_5509353_6 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003519 299.0
HFD3_k127_5509353_7 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000000001601 233.0
HFD3_k127_5509353_8 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000001593 226.0
HFD3_k127_5509353_9 permease - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000002459 207.0
HFD3_k127_5520122_0 Dehydratase family K01687 - 4.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002953 275.0
HFD3_k127_5520122_1 Belongs to the pseudouridine synthase RsuA family K06178,K06181,K06182 - 5.4.99.20,5.4.99.21,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000002351 251.0
HFD3_k127_5520122_2 Glycoprotease family K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.00000000000000000000000000000000000000000000000000000002114 204.0
HFD3_k127_5520122_3 Alpha beta - - - 0.0000000000000000000000000000000000002036 152.0
HFD3_k127_5520122_4 PFAM acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.0000000000000000000000000000002788 124.0
HFD3_k127_5520122_5 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000000000000000000003588 126.0
HFD3_k127_5520122_6 Domain of unknown function (DUF4253) - - - 0.0000000000000000000104 101.0
HFD3_k127_5522082_0 Domain of unknown function DUF11 - - - 0.0 2505.0
HFD3_k127_5522082_1 OmpA family - - - 0.0 2010.0
HFD3_k127_5522082_10 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000000004944 158.0
HFD3_k127_5522082_11 - - - - 0.000000000000000000000000002823 114.0
HFD3_k127_5522082_12 TIR domain - - - 0.00001215 56.0
HFD3_k127_5522082_2 Tetratricopeptide repeat - - - 0.0 1294.0
HFD3_k127_5522082_3 Tetratricopeptide repeat - - - 8.047e-282 877.0
HFD3_k127_5522082_4 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 486.0
HFD3_k127_5522082_5 MotA/TolQ/ExbB proton channel family K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 306.0
HFD3_k127_5522082_6 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001824 254.0
HFD3_k127_5522082_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000002323 215.0
HFD3_k127_5522082_8 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000000000000000000000000000000000004826 213.0
HFD3_k127_5522082_9 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000000000000000000000000000975 188.0
HFD3_k127_5529528_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 605.0
HFD3_k127_5529528_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 417.0
HFD3_k127_5529528_10 Ribosomal protein L6 K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000006252 221.0
HFD3_k127_5529528_11 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000001478 216.0
HFD3_k127_5529528_12 Forms part of the polypeptide exit tunnel K02926 - - 0.0000000000000000000000000000000000000000000000000000000000006229 216.0
HFD3_k127_5529528_13 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000001531 199.0
HFD3_k127_5529528_14 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000435 220.0
HFD3_k127_5529528_15 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000006148 197.0
HFD3_k127_5529528_16 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000000000000001646 194.0
HFD3_k127_5529528_17 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000009533 181.0
HFD3_k127_5529528_18 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000004314 175.0
HFD3_k127_5529528_19 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000003148 172.0
HFD3_k127_5529528_2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007673 392.0
HFD3_k127_5529528_20 histidine kinase HAMP region domain protein K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000108 186.0
HFD3_k127_5529528_21 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000001364 152.0
HFD3_k127_5529528_22 ribosomal protein l17 K02879 - - 0.000000000000000000000000000000000000005326 149.0
HFD3_k127_5529528_23 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000008374 145.0
HFD3_k127_5529528_24 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000000002024 141.0
HFD3_k127_5529528_25 Ribosomal proteins 50S L24/mitochondrial 39S L24 K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000009118 132.0
HFD3_k127_5529528_26 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000001306 129.0
HFD3_k127_5529528_27 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000007182 114.0
HFD3_k127_5529528_28 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000002361 111.0
HFD3_k127_5529528_29 protein-disulfide reductase activity - - - 0.00000000000000000000000002473 115.0
HFD3_k127_5529528_3 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 323.0
HFD3_k127_5529528_30 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000002328 107.0
HFD3_k127_5529528_31 Ribosomal protein L30 K02907 - - 0.00000000000000287 78.0
HFD3_k127_5529528_32 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000008823 74.0
HFD3_k127_5529528_33 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000000004605 73.0
HFD3_k127_5529528_34 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000009922 68.0
HFD3_k127_5529528_4 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007749 316.0
HFD3_k127_5529528_5 metal-dependent phosphohydrolase HD region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008975 320.0
HFD3_k127_5529528_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005587 297.0
HFD3_k127_5529528_7 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002079 264.0
HFD3_k127_5529528_8 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000184 257.0
HFD3_k127_5529528_9 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000000000007771 226.0
HFD3_k127_5541834_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009411 610.0
HFD3_k127_5541834_1 Bacterial sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002523 531.0
HFD3_k127_5541834_10 Autotransporter beta-domain - - - 0.0000000000000000154 97.0
HFD3_k127_5541834_11 Protein of unknown function (DUF3494) - - - 0.000000000004178 79.0
HFD3_k127_5541834_2 Secretion ATPase, PEP-CTERM locus subfamily K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008272 363.0
HFD3_k127_5541834_3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006248 343.0
HFD3_k127_5541834_4 Chain length determinant protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 299.0
HFD3_k127_5541834_5 Putative beta-barrel porin 2 - - - 0.000000000000000000000000000000000000000000000000000000000000002816 233.0
HFD3_k127_5541834_6 AAA domain K08252 - 2.7.10.1 0.0000000000000000000000000000000000000000000000000000000000002962 222.0
HFD3_k127_5541834_7 Polysaccharide biosynthesis/export protein K01991 - - 0.0000000000000000000000000000000000000000000000000000000000008287 220.0
HFD3_k127_5541834_8 Transcription termination factor nusG - - - 0.0000000000000000000000000000000000000000000000000009914 191.0
HFD3_k127_5541834_9 - - - - 0.00000000000000000000005627 102.0
HFD3_k127_5580785_0 Apoptosis-inducing factor, mitochondrion-associated, C-term - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 357.0
HFD3_k127_5580785_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000002256 235.0
HFD3_k127_5580785_2 Methyltransferase small domain - - - 0.000000000000000000000000000000000000000000000000005391 190.0
HFD3_k127_5580785_3 Dihydroneopterin aldolase - - - 0.000000000000000000000000000000000000000007834 161.0
HFD3_k127_5580785_4 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633,K07589 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008719,GO:0009987,GO:0016853,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0071704,GO:1901360,GO:1901564 1.13.11.81,4.1.2.25,5.1.99.7,5.1.99.8 0.000000000000000000000000000000000006077 140.0
HFD3_k127_5580785_5 gtp cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000000000000000000000000003342 127.0
HFD3_k127_5580785_6 diol metabolic process K01724 - 4.2.1.96 0.0000000000000000000000001425 109.0
HFD3_k127_5580785_7 Thioesterase-like superfamily K07107 - - 0.0000000000000005123 80.0
HFD3_k127_5586137_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1302.0
HFD3_k127_5586137_1 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1274.0
HFD3_k127_5586137_10 Hsp20/alpha crystallin family - - - 0.00000000000002162 78.0
HFD3_k127_5586137_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 8.883e-299 936.0
HFD3_k127_5586137_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 332.0
HFD3_k127_5586137_4 4Fe-4S dicluster domain K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008104 314.0
HFD3_k127_5586137_5 N-terminal domain of galactosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006576 300.0
HFD3_k127_5586137_6 4Fe-4S dicluster domain K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008368 280.0
HFD3_k127_5586137_7 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000001175 267.0
HFD3_k127_5586137_8 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000003075 261.0
HFD3_k127_5586137_9 Prokaryotic cytochrome b561 K00127 - - 0.00000000000000000000000000000000000008229 149.0
HFD3_k127_5595837_0 PFAM Rubrerythrin - GO:0003674,GO:0003824,GO:0004601,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0016692,GO:0022900,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001165 284.0
HFD3_k127_5595837_1 Phospholipase D. Active site motifs. K06131 - - 0.00000000000000000000000000000000000000000000000000000000000001863 229.0
HFD3_k127_5595837_2 Oxidoreductase NAD-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000002193 221.0
HFD3_k127_5595837_3 lyase activity - - - 0.00000000000003521 77.0
HFD3_k127_5595837_4 OsmC-like protein K07397 - - 0.00000000006405 64.0
HFD3_k127_5601175_0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase - - - 0.0 1397.0
HFD3_k127_5601175_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 427.0
HFD3_k127_5601175_2 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009721 406.0
HFD3_k127_5601175_3 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 384.0
HFD3_k127_5601175_4 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 374.0
HFD3_k127_5601175_5 Surface antigen K07277 - - 0.00000000000000000002014 106.0
HFD3_k127_5603246_0 PFAM Carbamoyl-phosphate synthase L chain ATP-binding K01955 - 6.3.5.5 0.0 1520.0
HFD3_k127_5603246_1 CBS domain containing protein K00974 - 2.7.7.72 1.003e-264 841.0
HFD3_k127_5603246_10 integrase domain protein SAM domain protein K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 316.0
HFD3_k127_5603246_11 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000007043 232.0
HFD3_k127_5603246_12 Peptidase MA superfamily - - - 0.000000000000000000000000000000000000000000000000000000000006321 222.0
HFD3_k127_5603246_13 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.00000000000000000000000000000000000000000000000000000000005522 214.0
HFD3_k127_5603246_14 PFAM Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000007846 183.0
HFD3_k127_5603246_15 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000002589 182.0
HFD3_k127_5603246_16 acid phosphatase activity - - - 0.00000000000000000000000000000000000000000004408 172.0
HFD3_k127_5603246_17 PFAM NADPH-dependent FMN reductase - - - 0.0000000000002127 70.0
HFD3_k127_5603246_18 - - - - 0.00000000004025 69.0
HFD3_k127_5603246_19 Sporulation related domain - - - 0.00000002017 64.0
HFD3_k127_5603246_2 TIGRFAM carbamoyl-phosphate synthase, small subunit K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 558.0
HFD3_k127_5603246_20 PD-(D/E)XK nuclease superfamily - - - 0.0002688 44.0
HFD3_k127_5603246_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008566 539.0
HFD3_k127_5603246_4 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004151 425.0
HFD3_k127_5603246_5 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005161 400.0
HFD3_k127_5603246_6 PFAM Na Picotransporter K03324 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006691 404.0
HFD3_k127_5603246_7 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 396.0
HFD3_k127_5603246_8 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 370.0
HFD3_k127_5603246_9 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004037 357.0
HFD3_k127_5631403_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 3.207e-264 828.0
HFD3_k127_5631403_1 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 580.0
HFD3_k127_5631403_2 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 367.0
HFD3_k127_5631403_3 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 348.0
HFD3_k127_5631403_4 PPIC-type PPIASE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 341.0
HFD3_k127_5631403_5 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003056 274.0
HFD3_k127_5631403_6 - - - - 0.0000000000000000000000000000000000002992 155.0
HFD3_k127_5631403_7 amine dehydrogenase activity - - - 0.00000000000000000000000000000005356 139.0
HFD3_k127_5631403_8 O-linked N-acetylglucosamine transferase SPINDLY family - - - 0.0000000000000000000000003616 114.0
HFD3_k127_5631403_9 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000006285 100.0
HFD3_k127_567891_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005682 505.0
HFD3_k127_567891_1 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005379 350.0
HFD3_k127_5681460_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 9.426e-313 989.0
HFD3_k127_5681460_1 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000001556 256.0
HFD3_k127_5681460_2 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000003935 198.0
HFD3_k127_5681460_3 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715,K15866,K20036 - 4.2.1.155,4.2.1.17,5.3.3.18 0.0000000000000000000000000000000000000000000000005871 184.0
HFD3_k127_5681460_4 Outer membrane efflux protein - - - 0.00000000003329 65.0
HFD3_k127_5681460_5 Regulatory protein, FmdB family - - - 0.000000002025 60.0
HFD3_k127_5701875_0 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000006931 246.0
HFD3_k127_5701875_1 Transcription termination factor nusG - - - 0.000000000000000000000000000000000000000007489 158.0
HFD3_k127_5701875_3 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.00000000000002002 74.0
HFD3_k127_5701875_4 PFAM sugar transferase - - - 0.0005809 42.0
HFD3_k127_5723179_0 Metallo-beta-lactamase superfamily K22405 - 1.6.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005076 602.0
HFD3_k127_5723179_1 Belongs to the Fur family K09825 - - 0.0000000000000000000000000000000000000001718 154.0
HFD3_k127_5723179_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000007551 122.0
HFD3_k127_5723179_3 PFAM Thiamine pyrophosphate enzyme, C-terminal TPP-binding K00158 - 1.2.3.3 0.0000000000000002657 79.0
HFD3_k127_5723179_4 Belongs to the UPF0758 family K03630 GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.00000007399 59.0
HFD3_k127_5738510_0 Transposase, Mutator family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 493.0
HFD3_k127_5738510_1 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 493.0
HFD3_k127_5738510_2 phosphorelay signal transduction system - - - 0.0000000000000000000000001845 111.0
HFD3_k127_5738510_3 - - - - 0.0000122 48.0
HFD3_k127_5760712_0 COG0457 FOG TPR repeat - - - 5.584e-265 826.0
HFD3_k127_5760712_1 Phage integrase family - - - 0.00000003469 55.0
HFD3_k127_5760712_2 HTH-like domain K07497 - - 0.000003682 48.0
HFD3_k127_5760712_3 Polysaccharide lyase family 4, domain II K02014 - - 0.0006689 46.0
HFD3_k127_5763641_0 Curli production assembly/transport component CsgG - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005843 367.0
HFD3_k127_5763641_1 Lipoprotein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005214 362.0
HFD3_k127_5763641_2 - - - - 0.00000000000000000000000000212 119.0
HFD3_k127_5793752_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.953e-306 950.0
HFD3_k127_5793752_1 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 457.0
HFD3_k127_5793752_2 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000001609 174.0
HFD3_k127_5793752_3 Protein involved in formate dehydrogenase formation K02380 - - 0.00000000000000000000000000000008255 136.0
HFD3_k127_5797773_0 Transglycosylase SLT domain K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006133 489.0
HFD3_k127_5797773_1 PFAM Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006531 449.0
HFD3_k127_5797773_10 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.00000089 51.0
HFD3_k127_5797773_2 Belongs to the RtcB family K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000007593 222.0
HFD3_k127_5797773_3 protein with SCP PR1 domains - - - 0.000000000000000000000000000000000000000000000000006544 187.0
HFD3_k127_5797773_4 Endoribonuclease L-PSP K09022 GO:0003674,GO:0003824,GO:0016787,GO:0019239 3.5.99.10 0.0000000000000000000000000000000000000000000392 163.0
HFD3_k127_5797773_5 Archease protein family (MTH1598/TM1083) - - - 0.00000000000000000000000000000000009997 138.0
HFD3_k127_5797773_6 PFAM Smr protein MutS2 - - - 0.0000000000000000000000000000001437 126.0
HFD3_k127_5797773_7 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000004638 131.0
HFD3_k127_5797773_8 Cytochrome c7 and related cytochrome c - - - 0.000000000000000006004 87.0
HFD3_k127_5797773_9 TIGRFAM Glutaredoxin-like domain protein - - - 0.0000001037 62.0
HFD3_k127_5825539_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 531.0
HFD3_k127_5825539_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004172 261.0
HFD3_k127_5825539_2 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000000000000000000000000000000007285 211.0
HFD3_k127_5825539_3 FixH - - - 0.000000000000000001347 91.0
HFD3_k127_5825539_4 PFAM FixH family protein - - - 0.000000049 60.0
HFD3_k127_5869218_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 520.0
HFD3_k127_5869218_1 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000006391 243.0
HFD3_k127_5869218_2 DGC domain - - - 0.000000000000000000000000000000000000000000000000000069 193.0
HFD3_k127_5869218_3 - - - - 0.00000000000000001761 89.0
HFD3_k127_5869218_4 Bacterial Ig-like domain 2 - - - 0.000000000002903 73.0
HFD3_k127_5869218_5 peptidyl-tyrosine sulfation - - - 0.0000000002117 69.0
HFD3_k127_5869218_6 Protein of unknown function (DUF3494) - - - 0.00000005267 64.0
HFD3_k127_5869218_7 Short C-terminal domain K08982 - - 0.00001132 51.0
HFD3_k127_58940_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 1.301e-258 806.0
HFD3_k127_58940_1 PFAM Cys Met metabolism K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 517.0
HFD3_k127_58940_10 - - - - 0.00000000000000000000000001808 115.0
HFD3_k127_58940_11 Outer membrane protein beta-barrel domain - - - 0.0000000000000000000000004149 113.0
HFD3_k127_58940_12 Glycogen debranching enzyme - - - 0.00000000000000002864 83.0
HFD3_k127_58940_13 Domain of unknown function (DUF4136) - - - 0.00000000000001721 80.0
HFD3_k127_58940_15 PFAM PRC-barrel domain - - - 0.0000000002376 66.0
HFD3_k127_58940_16 Belongs to the 'phage' integrase family - - - 0.00000001658 59.0
HFD3_k127_58940_17 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0004734 47.0
HFD3_k127_58940_2 regulation of DNA-templated transcription, elongation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 474.0
HFD3_k127_58940_3 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 426.0
HFD3_k127_58940_4 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009865 416.0
HFD3_k127_58940_5 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 334.0
HFD3_k127_58940_6 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 298.0
HFD3_k127_58940_7 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001132 286.0
HFD3_k127_58940_8 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000002503 167.0
HFD3_k127_58940_9 Ion channel - - - 0.0000000000000000000000000000009245 130.0
HFD3_k127_5942907_0 DNA topoisomerase II activity K02469,K02621 GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008150,GO:0008152,GO:0009330,GO:0009987,GO:0016020,GO:0016043,GO:0019897,GO:0019898,GO:0022402,GO:0030541,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0098813,GO:1901360,GO:1901363 5.99.1.3 1.02e-231 741.0
HFD3_k127_5942907_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 508.0
HFD3_k127_5982876_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 5.708e-314 979.0
HFD3_k127_5982876_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.935e-301 944.0
HFD3_k127_5982876_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007392 387.0
HFD3_k127_6024359_0 ABC transporter K06158 - - 2.644e-238 751.0
HFD3_k127_6024359_1 GtrA-like protein K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 390.0
HFD3_k127_6191_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.335e-287 902.0
HFD3_k127_6191_1 Response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 537.0
HFD3_k127_6191_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005961 304.0
HFD3_k127_6191_3 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 293.0
HFD3_k127_6191_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000003208 258.0
HFD3_k127_6191_5 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000004113 252.0
HFD3_k127_6191_6 protein conserved in bacteria (DUF2064) K09931 - - 0.000000000000000000000000003361 114.0
HFD3_k127_6191_7 Belongs to the Smg family K03747 - - 0.0000004035 58.0
HFD3_k127_6206942_0 PFAM Cytochrome b5 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008149 291.0
HFD3_k127_6206942_1 denitrification pathway - - - 0.000000000000000000000000000000000000000004939 164.0
HFD3_k127_6206942_4 COG2010 Cytochrome c, mono- and diheme variants K02305 - - 0.00000000000000004417 84.0
HFD3_k127_6206942_5 Cytochrome c K02305 - - 0.000000000007884 68.0
HFD3_k127_6206942_6 Cupin 2, conserved barrel domain protein - - - 0.00000000002863 68.0
HFD3_k127_6224289_0 glutamate synthase alpha subunit domain protein K00265 - 1.4.1.13,1.4.1.14 0.0 1809.0
HFD3_k127_6224289_1 PFAM Radical SAM - - - 2.662e-217 684.0
HFD3_k127_6224289_10 NTPase - - - 0.00000000000000000000000000000000000000000000000000000009493 199.0
HFD3_k127_6224289_11 Response regulator containing a CheY-like receiver domain and an HD-GYP domain - - - 0.00000000000000000000000000000000000000000000000000002909 196.0
HFD3_k127_6224289_12 HAD-superfamily hydrolase subfamily IA, variant 3 K07025 - - 0.000000000000000000000000000000000000000000000000001702 191.0
HFD3_k127_6224289_13 Peptidase family M54 K06974 - - 0.000000000000000000000000000000000000000000000078 184.0
HFD3_k127_6224289_14 COGs COG4446 conserved - - - 0.000000000000000000000000000000000000000000002156 169.0
HFD3_k127_6224289_15 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000002072 150.0
HFD3_k127_6224289_16 protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000000000000002424 148.0
HFD3_k127_6224289_17 Transposase IS116/IS110/IS902 family - - - 0.0000000000000000000000000000000000002706 143.0
HFD3_k127_6224289_18 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000002534 109.0
HFD3_k127_6224289_19 Domain of unknown function (DUF1956) - - - 0.000000001712 68.0
HFD3_k127_6224289_2 Fructose-1,6-bisphosphatase K01622 - 3.1.3.11,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006152 572.0
HFD3_k127_6224289_20 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000003593 61.0
HFD3_k127_6224289_21 Belongs to the anti-sigma-factor antagonist family K06378 - - 0.0000004229 57.0
HFD3_k127_6224289_3 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 464.0
HFD3_k127_6224289_4 Phospholipase, patatin family K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 352.0
HFD3_k127_6224289_5 PFAM MscS Mechanosensitive ion channel K03442 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000013 273.0
HFD3_k127_6224289_6 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000002882 271.0
HFD3_k127_6224289_7 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000001055 259.0
HFD3_k127_6224289_8 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000007131 243.0
HFD3_k127_6224289_9 tRNA modification K06968 - 2.1.1.186 0.0000000000000000000000000000000000000000000000000000000000000001626 226.0
HFD3_k127_6229274_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006395 591.0
HFD3_k127_6229274_1 Evidence 2b Function of strongly homologous gene - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 565.0
HFD3_k127_6229274_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007417 535.0
HFD3_k127_6229274_3 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000002542 65.0
HFD3_k127_6229274_4 COG NOG19146 non supervised orthologous group - - - 0.000003462 50.0
HFD3_k127_6229274_6 Protein of unknown function (DUF1573) - - - 0.0001674 47.0
HFD3_k127_6229876_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 364.0
HFD3_k127_6229876_1 nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006341 329.0
HFD3_k127_6229876_2 Mechanosensitive ion channel K03442 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007934 316.0
HFD3_k127_6229876_3 MgsA AAA+ ATPase C terminal K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000003294 235.0
HFD3_k127_6229876_4 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000001411 69.0
HFD3_k127_6231499_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1307.0
HFD3_k127_6231499_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.71e-243 760.0
HFD3_k127_6231499_2 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006965 595.0
HFD3_k127_6231499_3 FAD binding domain K00278 - 1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003776 571.0
HFD3_k127_6231499_4 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 340.0
HFD3_k127_6231499_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000001759 107.0
HFD3_k127_6231499_6 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000001348 92.0
HFD3_k127_6231499_7 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000001452 67.0
HFD3_k127_6231499_8 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000004006 61.0
HFD3_k127_6239848_0 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007561 497.0
HFD3_k127_6239848_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007578 456.0
HFD3_k127_6239848_2 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000002507 144.0
HFD3_k127_6239848_3 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.0005155 46.0
HFD3_k127_6239848_4 PFAM Cyclic nucleotide-binding - - - 0.0006591 45.0
HFD3_k127_6248040_0 Part of a membrane complex involved in electron transport K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 524.0
HFD3_k127_6248040_1 Part of a membrane complex involved in electron transport K03614 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 358.0
HFD3_k127_6248040_2 electron transport complex, RnfABCDGE type, B subunit K03616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000938 343.0
HFD3_k127_6248040_3 Part of a membrane complex involved in electron transport K03617 - - 0.000000000000000000000000000000000000000000000000000000000000000000181 234.0
HFD3_k127_6248040_4 Part of a membrane complex involved in electron transport K03613 - - 0.00000000000000000000000000000000000000000000000000000000000000007302 230.0
HFD3_k127_6248040_5 PFAM nitrogen-fixing NifU domain protein - - - 0.000000000000000000000000004723 111.0
HFD3_k127_6248040_6 Part of a membrane complex involved in electron transport K03612 - - 0.00000000000000000000009076 106.0
HFD3_k127_6248040_7 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000004453 61.0
HFD3_k127_6248181_0 Catalyzes the formation of citrate from acetyl-CoA and oxaloacetate K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000001182 225.0
HFD3_k127_6248181_1 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000002531 157.0
HFD3_k127_6248181_2 Response receiver-modulated nucleotide cyclase, GGDEF-related domain-containing - - - 0.00001448 49.0
HFD3_k127_6249121_0 Protein involved in outer membrane biogenesis - - - 1.321e-251 807.0
HFD3_k127_6249121_1 Thioredoxin-like domain K03671 - - 0.0000000000000000000000000000000000000000004396 159.0
HFD3_k127_6249121_2 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.000000000000000000000000000000000000004184 169.0
HFD3_k127_6249121_3 cell redox homeostasis K02199 - - 0.00000000000000000000000000000266 127.0
HFD3_k127_6249121_4 4Fe-4S binding domain - - - 0.000000000001163 69.0
HFD3_k127_6257227_0 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000002064 221.0
HFD3_k127_6257227_1 Predicted membrane protein (DUF2232) - - - 0.0000000000000000003255 98.0
HFD3_k127_6257227_2 Protein of unknown function (DUF507) - - - 0.000000000000003558 78.0
HFD3_k127_6257227_3 Protein of unknown function (DUF507) - - - 0.000000000000006514 80.0
HFD3_k127_6257227_4 Sigma-70 region 2 K03088 - - 0.00000009584 54.0
HFD3_k127_6264005_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0 1100.0
HFD3_k127_6264005_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000167 262.0
HFD3_k127_6264005_2 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000002402 155.0
HFD3_k127_6265583_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 607.0
HFD3_k127_6265583_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007396 570.0
HFD3_k127_6265583_2 Transposase, IS605 OrfB family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 446.0
HFD3_k127_6265583_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 392.0
HFD3_k127_6265583_4 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 297.0
HFD3_k127_6265583_5 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000153 276.0
HFD3_k127_6265583_6 recombinase activity K07450 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003109 254.0
HFD3_k127_6265583_7 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000002227 237.0
HFD3_k127_6265583_8 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000003597 228.0
HFD3_k127_6265583_9 O-methyltransferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000005708 218.0
HFD3_k127_6266048_0 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 292.0
HFD3_k127_6266048_1 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000002363 173.0
HFD3_k127_6266048_2 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000006594 158.0
HFD3_k127_6266048_3 Sulphur transport - - - 0.00000000000000000000000000000000005128 139.0
HFD3_k127_6266048_4 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000002995 73.0
HFD3_k127_6266048_5 integral membrane protein - - - 0.00000001906 63.0
HFD3_k127_6271659_0 Histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007143 381.0
HFD3_k127_6271659_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006128 317.0
HFD3_k127_6274434_0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008473 307.0
HFD3_k127_6274434_1 PFAM PP-loop domain protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008322 304.0
HFD3_k127_6274434_2 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 299.0
HFD3_k127_6274434_3 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 294.0
HFD3_k127_6274434_4 regulatory protein IclR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005635 271.0
HFD3_k127_6274434_5 PFAM Rhodanese domain protein - - - 0.000000000001839 70.0
HFD3_k127_6274434_6 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K01760 - 4.4.1.8 0.000001612 50.0
HFD3_k127_6279723_0 ISXO2-like transposase domain - - - 0.00000000000002527 78.0
HFD3_k127_6279723_1 light absorption - - - 0.0000000005405 62.0
HFD3_k127_6279723_2 IS116 IS110 IS902 family K07486 - - 0.00000002078 62.0
HFD3_k127_6279723_3 - - - - 0.000001413 59.0
HFD3_k127_6279723_4 - - - - 0.00003175 51.0
HFD3_k127_6279723_5 SEFIR domain - - - 0.0000872 50.0
HFD3_k127_6279723_6 Pkd domain containing protein - - - 0.0006268 50.0
HFD3_k127_6286304_0 NosL - - - 0.00000000000000000000000000000000000003004 148.0
HFD3_k127_6286304_1 (ABC) transporter - - - 0.0000000000000000000000000000001617 131.0
HFD3_k127_6286304_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000005246 126.0
HFD3_k127_6286304_3 (ABC) transporter - - - 0.000000000000000332 86.0
HFD3_k127_6286304_5 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000005275 62.0
HFD3_k127_6286304_6 - - - - 0.0000005152 61.0
HFD3_k127_6298991_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007874 469.0
HFD3_k127_6298991_1 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006263 441.0
HFD3_k127_6298991_2 COG0058 Glucan phosphorylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 404.0
HFD3_k127_6298991_3 Catalyzes the phosphorylation of D-glycero-D-manno- heptose 7-phosphate at the C-1 position to selectively form D- glycero-beta-D-manno-heptose-1,7-bisphosphate K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000611 186.0
HFD3_k127_6298991_4 Zincin-like metallopeptidase K00930 - 2.7.2.8 0.000000000000000000000001953 108.0
HFD3_k127_6298991_5 General secretory system II protein E domain protein K02652 - - 0.0000004751 54.0
HFD3_k127_6307215_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.663e-266 837.0
HFD3_k127_6307215_1 DHH family K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 355.0
HFD3_k127_6307872_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 2.875e-236 741.0
HFD3_k127_6307872_1 Adenylate kinase, active site lid K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000593 324.0
HFD3_k127_6307872_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.0000000000000000000000000000000000000000000000000000006367 194.0
HFD3_k127_6307872_3 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000000002448 189.0
HFD3_k127_6307872_4 - - - - 0.00000000000002858 81.0
HFD3_k127_6307872_5 Tetratricopeptide repeats - - - 0.00000000002629 70.0
HFD3_k127_6313346_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009583 486.0
HFD3_k127_6313346_1 binding domain protein K07138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 426.0
HFD3_k127_6313346_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299 - 1.17.1.10,1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000001774 218.0
HFD3_k127_6313346_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000001759 120.0
HFD3_k127_6320659_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1454.0
HFD3_k127_6320659_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 3.303e-320 989.0
HFD3_k127_6320659_3 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005219 338.0
HFD3_k127_6320659_4 Uncharacterised conserved protein (DUF2156) K01163 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000866 327.0
HFD3_k127_6320659_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K14986 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 305.0
HFD3_k127_6320659_6 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 289.0
HFD3_k127_6320659_7 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002662 290.0
HFD3_k127_6320659_8 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000007452 224.0
HFD3_k127_6320659_9 response regulator - - - 0.00000004086 57.0
HFD3_k127_6325154_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009573 469.0
HFD3_k127_6325154_1 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000004796 219.0
HFD3_k127_6350017_0 Winged helix-turn helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004708 310.0
HFD3_k127_6350017_1 Cytochrome b/b6/petB K03887 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000573 275.0
HFD3_k127_6350017_2 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000000000001629 128.0
HFD3_k127_6350017_4 Glycosyltransferase like family 2 - - - 0.000000000000006748 76.0
HFD3_k127_6352594_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K00558,K03572 GO:0000018,GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 2.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 451.0
HFD3_k127_6352594_1 PFAM PfkB domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 424.0
HFD3_k127_6352594_2 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 383.0
HFD3_k127_6352594_3 PFAM Integral membrane protein TerC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009984 322.0
HFD3_k127_6352594_4 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006966 297.0
HFD3_k127_6352594_5 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000009247 96.0
HFD3_k127_6352594_6 Peptidase M16 domain protein K07263 - - 0.00000000000000001377 83.0
HFD3_k127_6352594_7 - - - - 0.0005693 43.0
HFD3_k127_6354574_0 phosphorelay signal transduction system K07712,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 428.0
HFD3_k127_6354574_1 Nitrogen fixation master sensor histidine kinase, PAS domain-containing K02668,K07708,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009801 282.0
HFD3_k127_6354574_2 - - - - 0.00000000000000002031 83.0
HFD3_k127_6365409_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008481 544.0
HFD3_k127_6365409_1 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 509.0
HFD3_k127_6365409_10 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000007514 235.0
HFD3_k127_6365409_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000002742 232.0
HFD3_k127_6365409_12 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000000000212 185.0
HFD3_k127_6365409_13 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000002195 185.0
HFD3_k127_6365409_14 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000006163 164.0
HFD3_k127_6365409_15 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000005153 140.0
HFD3_k127_6365409_16 Could be involved in septation K06412 - - 0.000000000000000000000000000000006869 129.0
HFD3_k127_6365409_17 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000003799 127.0
HFD3_k127_6365409_18 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000002632 102.0
HFD3_k127_6365409_19 Regulatory protein, FmdB family - - - 0.00000000000000000002316 93.0
HFD3_k127_6365409_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 417.0
HFD3_k127_6365409_20 Uncharacterized ACR, COG1430 K09005 - - 0.000000002321 70.0
HFD3_k127_6365409_21 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000003286 67.0
HFD3_k127_6365409_22 cyclic nucleotide binding K07001,K10914 - - 0.0001211 45.0
HFD3_k127_6365409_23 Cyclic nucleotide-monophosphate binding domain - - - 0.000842 46.0
HFD3_k127_6365409_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007353 407.0
HFD3_k127_6365409_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004432 359.0
HFD3_k127_6365409_5 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 303.0
HFD3_k127_6365409_6 COG1055 Na H antiporter NhaD and related arsenite permeases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009011 316.0
HFD3_k127_6365409_7 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009854 274.0
HFD3_k127_6365409_8 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000002552 268.0
HFD3_k127_6365409_9 Belongs to the UPF0282 family K07022 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003994 269.0
HFD3_k127_6366171_0 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 338.0
HFD3_k127_6366171_1 methyltransferase - - - 0.000000000000000000000000000000000000000000000000007885 188.0
HFD3_k127_6366171_2 4Fe-4S binding domain - - - 0.00000000000006932 77.0
HFD3_k127_6366171_3 - - - - 0.0000209 51.0
HFD3_k127_6366171_4 PFAM Transposase, IS605 OrfB K07496 - - 0.00002705 47.0
HFD3_k127_6379599_0 Domain of unknown function (DUF4382) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 334.0
HFD3_k127_6379599_1 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000386 251.0
HFD3_k127_6379599_2 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.000000007267 59.0
HFD3_k127_6390400_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 8.884e-257 806.0
HFD3_k127_6390400_1 Polyprenyl synthetase K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 346.0
HFD3_k127_6390400_2 Protein of unknown function (DUF1622) - - - 0.00000000000000000000000000000008123 128.0
HFD3_k127_6390400_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000001265 57.0
HFD3_k127_6398068_0 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 475.0
HFD3_k127_6398068_1 UbiE COQ5 methyltransferase K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 368.0
HFD3_k127_6398068_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000003268 252.0
HFD3_k127_6398068_3 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000000000000000000000001249 231.0
HFD3_k127_6398068_4 Putative Fe-S cluster - - - 0.00000000000000000000000000000000000000000000000000000000000000006381 226.0
HFD3_k127_6398068_5 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000000000000000000001977 149.0
HFD3_k127_6398068_6 PFAM Thioredoxin K03671 - - 0.00000000000000000000005742 103.0
HFD3_k127_6398068_7 Thioredoxin domain - - - 0.0000000000000000000001271 99.0
HFD3_k127_6398068_8 - - - - 0.0005913 44.0
HFD3_k127_6414309_0 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005688 555.0
HFD3_k127_6414309_1 DNA polymerase LigD polymerase domain K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 301.0
HFD3_k127_6414309_2 AsmA-like C-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007612 300.0
HFD3_k127_6414309_3 PFAM Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000001625 266.0
HFD3_k127_6414309_4 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000001165 202.0
HFD3_k127_6414309_5 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000001002 172.0
HFD3_k127_6414309_6 Protein of unknown function DUF72 - - - 0.00000000000000000000000005158 108.0
HFD3_k127_6414309_7 PFAM Mo-co oxidoreductase dimerisation domain - - - 0.00007975 52.0
HFD3_k127_6418767_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004827 498.0
HFD3_k127_6418767_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000003221 226.0
HFD3_k127_6418767_2 Domain in cystathionine beta-synthase and other proteins. K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000001406 229.0
HFD3_k127_6418767_3 PHP-associated K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000001042 198.0
HFD3_k127_6418767_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000006324 180.0
HFD3_k127_6418767_5 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000000000003224 168.0
HFD3_k127_6418767_6 DRTGG domain - - - 0.0000000000000000000000000000002145 126.0
HFD3_k127_6418767_7 DRTGG domain - - - 0.00000000000000000000000006946 110.0
HFD3_k127_6437433_0 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006188 558.0
HFD3_k127_6437433_1 Ammonium Transporter K03320 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 479.0
HFD3_k127_6437433_10 Hemerythrin HHE cation binding domain K07216 - - 0.00000000000000000000001291 104.0
HFD3_k127_6437433_11 - - - - 0.00000000000000000000005862 100.0
HFD3_k127_6437433_12 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.000000001287 59.0
HFD3_k127_6437433_13 histidine kinase A domain protein - - - 0.0000001147 57.0
HFD3_k127_6437433_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 438.0
HFD3_k127_6437433_3 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.00000000000000000000000000000000000000000000000000000000001271 223.0
HFD3_k127_6437433_4 DIM6 NTAB family - - - 0.00000000000000000000000000000000000000000000000000005373 193.0
HFD3_k127_6437433_5 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000001995 181.0
HFD3_k127_6437433_6 at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA) K04751,K04752 - - 0.00000000000000000000000000000000000000000000009612 170.0
HFD3_k127_6437433_7 at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA) K04751,K04752 - - 0.00000000000000000000000000000000000000000004036 162.0
HFD3_k127_6437433_8 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000002421 140.0
HFD3_k127_6437433_9 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000246 143.0
HFD3_k127_6449411_0 Asparagine synthase K01953 - 6.3.5.4 1.556e-228 725.0
HFD3_k127_6449411_1 PFAM AMP-dependent synthetase and ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 565.0
HFD3_k127_6449411_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K09251 - 2.6.1.82 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 361.0
HFD3_k127_6449411_3 Domain of unknown function (DUF3473) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 346.0
HFD3_k127_6449411_4 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007386 304.0
HFD3_k127_6449411_5 RmlD substrate binding domain K01784,K02473,K03274,K08678 - 4.1.1.35,5.1.3.2,5.1.3.20,5.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008148 300.0
HFD3_k127_6449411_6 TIGRFAM N-acetyl sugar amidotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001364 276.0
HFD3_k127_6449411_7 Protein of unknown function (DUF3485) - - - 0.000000000000000000000000000000000000000236 168.0
HFD3_k127_6449411_8 acyl carrier protein - - - 0.00000000000000000007857 92.0
HFD3_k127_6449411_9 domain, Protein K02014,K12287,K16087 - - 0.000000000000001885 81.0
HFD3_k127_6456518_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 457.0
HFD3_k127_6456518_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 301.0
HFD3_k127_6456518_10 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0031123,GO:0031404,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 0.00000000001041 71.0
HFD3_k127_6456518_11 DsrE/DsrF-like family - - - 0.00000002291 60.0
HFD3_k127_6456518_12 Belongs to the bacterial ribosomal protein bL34 family K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000001229 52.0
HFD3_k127_6456518_2 HD domain K07023 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001044 273.0
HFD3_k127_6456518_3 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000000000000000003441 205.0
HFD3_k127_6456518_4 Adenylate kinase - - - 0.000000000000000000000000000000000000000000000287 175.0
HFD3_k127_6456518_5 Histidine biosynthesis bifunctional protein HisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000001735 161.0
HFD3_k127_6456518_6 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.0000000000000000000000000000000000000000008044 159.0
HFD3_k127_6456518_7 Belongs to the Nudix hydrolase family - - - 0.0000000000000000000000000000693 120.0
HFD3_k127_6456518_8 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000000000000000000001047 105.0
HFD3_k127_6456518_9 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000004033 103.0
HFD3_k127_6463341_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 5.377e-202 658.0
HFD3_k127_6463341_1 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 443.0
HFD3_k127_6463341_2 histidine kinase HAMP region domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 382.0
HFD3_k127_6463341_3 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000004928 166.0
HFD3_k127_6463341_4 Beta-lactamase K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000000958 173.0
HFD3_k127_6463341_5 Beta-lactamase K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000005495 170.0
HFD3_k127_6471095_0 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005007 402.0
HFD3_k127_6471095_1 Pfam:Pyridox_oxidase - - - 0.000000000000000000000005111 106.0
HFD3_k127_6471095_2 Protein conserved in bacteria K01153 - 3.1.21.3 0.00000000000000000003226 95.0
HFD3_k127_6471095_3 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000003796 75.0
HFD3_k127_6478285_0 glucose sorbosone K00117 - 1.1.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 486.0
HFD3_k127_6478285_1 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000001429 222.0
HFD3_k127_6478285_2 Fe-S cluster domain protein - - - 0.000000000000000000000000000000002268 139.0
HFD3_k127_6503590_0 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 1.99e-218 690.0
HFD3_k127_6503590_1 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000001017 236.0
HFD3_k127_6507183_0 PFAM peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.0 1211.0
HFD3_k127_6507183_1 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003295 415.0
HFD3_k127_6507183_10 alpha/beta hydrolase fold - - - 0.000001395 51.0
HFD3_k127_6507183_11 PilZ domain - - - 0.0001466 52.0
HFD3_k127_6507183_2 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 404.0
HFD3_k127_6507183_3 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 358.0
HFD3_k127_6507183_4 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 346.0
HFD3_k127_6507183_5 histidine kinase, HAMP K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000004218 273.0
HFD3_k127_6507183_6 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006552 251.0
HFD3_k127_6507183_7 PFAM Cold-shock protein, DNA-binding - - - 0.0000000000000000000000000000000000000000000000000000000001001 209.0
HFD3_k127_6507183_8 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.00000000000000000000000000000000000000000000000000000002131 205.0
HFD3_k127_6507183_9 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide - - - 0.0000000002117 61.0
HFD3_k127_6521340_0 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 563.0
HFD3_k127_6521340_1 alpha-glucan phosphorylase K00688 - 2.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 346.0
HFD3_k127_6521340_2 phosphonoacetaldehyde hydrolase activity K00817,K07025,K20866 - 2.6.1.9,3.1.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 315.0
HFD3_k127_6521340_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000005445 204.0
HFD3_k127_6521340_4 - - - - 0.000000000000000000000000000000000000000000000000000001503 194.0
HFD3_k127_6521340_5 Evidence 4 Homologs of previously reported genes of - - - 0.00000001183 63.0
HFD3_k127_6521340_6 Protein of unknown function (DUF2934) - - - 0.000000049 57.0
HFD3_k127_6521340_7 DNA integration K14059 - - 0.0000003267 55.0
HFD3_k127_6521340_8 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0001502 50.0
HFD3_k127_6545060_0 ABC transporter K06020 - 3.6.3.25 1.4e-305 943.0
HFD3_k127_6545060_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 516.0
HFD3_k127_6545060_2 Protein of unknown function (DUF1255) K09913 - 2.4.2.1,2.4.2.2 0.00000000000000000000000000000000000000000000001665 171.0
HFD3_k127_6545060_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000365 132.0
HFD3_k127_6545060_4 SMART Tetratricopeptide - - - 0.00000000000000000000000000007101 123.0
HFD3_k127_6580172_0 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006404 584.0
HFD3_k127_6580172_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001489 269.0
HFD3_k127_6580172_2 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000002503 260.0
HFD3_k127_6580172_3 Molybdopterin-guanine dinucleotide biosynthesis K03753 - - 0.000000000000000000000000000000000001918 146.0
HFD3_k127_6580172_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117 - - 0.000000000000005975 79.0
HFD3_k127_6580172_5 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.000000002251 59.0
HFD3_k127_6607593_0 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 336.0
HFD3_k127_6607593_1 ATPases associated with a variety of cellular activities K02003,K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002525 254.0
HFD3_k127_6607593_2 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003743 251.0
HFD3_k127_6607593_3 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000004696 192.0
HFD3_k127_6607593_4 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000009895 190.0
HFD3_k127_6607593_5 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000001689 145.0
HFD3_k127_6607593_7 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.0000000003312 67.0
HFD3_k127_6607593_8 COG2801 Transposase and inactivated derivatives - - - 0.000009161 49.0
HFD3_k127_6631750_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 574.0
HFD3_k127_6631750_1 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004119 430.0
HFD3_k127_6631750_10 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000004718 115.0
HFD3_k127_6631750_11 thiamine biosynthesis protein ThiS K03154 - - 0.00000000001104 68.0
HFD3_k127_6631750_2 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 422.0
HFD3_k127_6631750_3 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006276 368.0
HFD3_k127_6631750_4 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000000000000000000005089 200.0
HFD3_k127_6631750_5 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.00000000000000000000000000000000000000000000000000001033 196.0
HFD3_k127_6631750_6 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.000000000000000000000000000000000000000000000006132 177.0
HFD3_k127_6631750_7 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000004123 174.0
HFD3_k127_6631750_8 Protein of unknown function (DUF3047) - - - 0.00000000000000000000000000000000000000000002607 169.0
HFD3_k127_6631750_9 Cobalamin-5-phosphate synthase K02233 - 2.7.8.26 0.000000000000000000000000000000000000004749 155.0
HFD3_k127_6650076_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 538.0
HFD3_k127_6650076_1 YtkA-like - - - 0.000008413 53.0
HFD3_k127_6650076_2 Isoprenylcysteine carboxyl methyltransferase - - - 0.0004131 46.0
HFD3_k127_6668535_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.256e-319 996.0
HFD3_k127_6668535_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 477.0
HFD3_k127_6668535_10 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000003554 269.0
HFD3_k127_6668535_11 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000002965 263.0
HFD3_k127_6668535_12 glycosyl transferase family 2 K00721,K00786 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000002419 259.0
HFD3_k127_6668535_13 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002918 252.0
HFD3_k127_6668535_14 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000021 236.0
HFD3_k127_6668535_15 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000004856 211.0
HFD3_k127_6668535_16 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000000000000000000003643 162.0
HFD3_k127_6668535_17 PFAM CBS domain - - - 0.0000000000000000000000000000000000000000006084 161.0
HFD3_k127_6668535_18 - - - - 0.000000000000000000000000000000004646 133.0
HFD3_k127_6668535_19 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.0000000000000000000000000000006507 126.0
HFD3_k127_6668535_2 Utp--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 389.0
HFD3_k127_6668535_20 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000003598 125.0
HFD3_k127_6668535_21 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000003956 119.0
HFD3_k127_6668535_22 Uncharacterized conserved protein (DUF2304) K09153 - - 0.00000000000000000008186 93.0
HFD3_k127_6668535_23 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000001881 57.0
HFD3_k127_6668535_3 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005444 395.0
HFD3_k127_6668535_4 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 322.0
HFD3_k127_6668535_5 Glycosyl transferase family group 2 K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 311.0
HFD3_k127_6668535_6 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006059 302.0
HFD3_k127_6668535_7 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 295.0
HFD3_k127_6668535_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005574 287.0
HFD3_k127_6668535_9 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000195 273.0
HFD3_k127_6691870_0 BadF BadG BcrA BcrD - - - 0.0 1455.0
HFD3_k127_6691870_1 Domain of unknown function (DUF4105) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006168 621.0
HFD3_k127_6691870_2 TIGRFAM siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000000000000000000008222 198.0
HFD3_k127_6691870_3 Protein of unknown function (DUF3015) - - - 0.0000000000000000000000000000000000000000000000001338 181.0
HFD3_k127_6691870_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000002956 146.0
HFD3_k127_6691870_5 Domain of unknown function (DUF4388) - - - 0.0000000000000000000006258 111.0
HFD3_k127_6691870_6 unfolded protein binding - - - 0.0000000001069 74.0
HFD3_k127_6725398_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 593.0
HFD3_k127_6725398_1 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 578.0
HFD3_k127_6725398_2 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 420.0
HFD3_k127_6725398_3 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000434 361.0
HFD3_k127_6725398_4 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 305.0
HFD3_k127_6725398_5 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000003188 214.0
HFD3_k127_6725398_6 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000004531 150.0
HFD3_k127_6731589_0 Belongs to the PEP-utilizing enzyme family K01006,K22424 - 2.7.3.13,2.7.9.1 0.0 1157.0
HFD3_k127_6731589_1 Sigma factor PP2C-like phosphatases K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 436.0
HFD3_k127_6731589_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 407.0
HFD3_k127_6731589_3 phosphatase activity K20881 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000001183 263.0
HFD3_k127_6731589_4 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000003785 202.0
HFD3_k127_6731589_5 Domain of unknown function (DUF202) K00389 - - 0.000000000000000000000000000000000000000000002708 168.0
HFD3_k127_6731589_6 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00000000000001833 75.0
HFD3_k127_6746817_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 5.844e-216 678.0
HFD3_k127_6746817_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006277 582.0
HFD3_k127_6746817_10 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000002603 222.0
HFD3_k127_6746817_11 Pyruvate ferredoxin/flavodoxin oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000003529 207.0
HFD3_k127_6746817_12 OmpA family K02557 - - 0.000000000000000000000000000000000000000000000000000003839 200.0
HFD3_k127_6746817_13 Formylmethanofuran dehydrogenase, subunit e K11261 - 1.2.7.12 0.000000000000000000000000000000000000000000000000001198 189.0
HFD3_k127_6746817_14 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000003975 135.0
HFD3_k127_6746817_15 cobalt ion transport K02009 - - 0.000000000000000000000001101 108.0
HFD3_k127_6746817_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006098 574.0
HFD3_k127_6746817_3 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 365.0
HFD3_k127_6746817_4 AAA domain, putative AbiEii toxin, Type IV TA system K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005677 294.0
HFD3_k127_6746817_5 cobalt ion transport K02007 GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015675,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000000000000000000000000000000000000002341 258.0
HFD3_k127_6746817_6 TIGRFAM riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000002602 243.0
HFD3_k127_6746817_7 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000002065 234.0
HFD3_k127_6746817_8 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000103 234.0
HFD3_k127_6746817_9 Cobalt transport protein K02008 - - 0.00000000000000000000000000000000000000000000000000000000000007814 223.0
HFD3_k127_6796_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 8.684e-302 949.0
HFD3_k127_6796_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 488.0
HFD3_k127_6796_2 Protein of unknown function (DUF3365) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 349.0
HFD3_k127_6796_3 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002022 268.0
HFD3_k127_6796_4 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000004279 161.0
HFD3_k127_6826819_0 Acyl transferase domain - - - 0.0 3771.0
HFD3_k127_6826819_1 SMART Elongator protein 3 MiaB NifB - - - 2.84e-239 745.0
HFD3_k127_6826819_10 PFAM Integrase catalytic region K07497 - - 0.00000000000002618 74.0
HFD3_k127_6826819_2 acetyltransferase - - - 3.234e-200 628.0
HFD3_k127_6826819_3 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005829 584.0
HFD3_k127_6826819_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006009 523.0
HFD3_k127_6826819_5 ABC transporter K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008924 481.0
HFD3_k127_6826819_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 419.0
HFD3_k127_6826819_7 lysine biosynthetic process via aminoadipic acid K00997,K06133 - 2.7.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003921 274.0
HFD3_k127_6826819_8 membrane organization K20543 - - 0.00000000000000000000000000000000000000000000000000000000000000000001026 250.0
HFD3_k127_6826819_9 Virulence factor BrkB K07058 - - 0.000000000000000000000000000003694 126.0
HFD3_k127_69376_0 Type IV pilus assembly protein PilM; K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 350.0
HFD3_k127_69376_1 PFAM Hly-III family protein K11068 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008385 275.0
HFD3_k127_69376_2 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.00000000000000000000000000000000000000000000000000000000000000114 222.0
HFD3_k127_69376_3 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000000457 112.0
HFD3_k127_69376_4 Pilus assembly protein, PilP K02665 - - 0.00000000000000000000007557 105.0
HFD3_k127_69376_5 Fimbrial assembly protein (PilN) K02663 - - 0.000000000000001029 85.0
HFD3_k127_69376_6 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K11686,K13640,K18997 - - 0.0000000000008957 71.0
HFD3_k127_6939662_0 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 378.0
HFD3_k127_6939662_1 peptidyl-lysine modification to peptidyl-hypusine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006983 369.0
HFD3_k127_6939662_10 Transcriptional regulator K11921,K19338 - - 0.000000000000000000000000000000000000000000000001292 185.0
HFD3_k127_6939662_11 TIGRFAM 2-methylcitrate synthase citrate synthase II K01647,K01659 - 2.3.3.1,2.3.3.5 0.0000000000000000000000000000000000000000001127 166.0
HFD3_k127_6939662_12 cytochrome c biogenesis protein - - - 0.0000000000000000000000000000000039 137.0
HFD3_k127_6939662_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 343.0
HFD3_k127_6939662_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 313.0
HFD3_k127_6939662_4 Binding-protein-dependent transport system inner membrane component K05773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 293.0
HFD3_k127_6939662_5 ABC-type tungstate transport system permease component-like protein K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001187 277.0
HFD3_k127_6939662_6 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004515 270.0
HFD3_k127_6939662_7 ATPase activity K02010,K02049,K02068,K02071,K06857,K10112 - 3.6.3.30,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000001822 264.0
HFD3_k127_6939662_8 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000001236 246.0
HFD3_k127_6939662_9 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000001723 236.0
HFD3_k127_6966040_0 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 596.0
HFD3_k127_6966040_1 Psort location CytoplasmicMembrane, score K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003442 304.0
HFD3_k127_6966040_10 Predicted membrane protein (DUF2318) - - - 0.00000001183 63.0
HFD3_k127_6966040_11 carbon monoxide dehydrogenase - - - 0.00001614 53.0
HFD3_k127_6966040_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006752 307.0
HFD3_k127_6966040_3 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 296.0
HFD3_k127_6966040_4 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002986 265.0
HFD3_k127_6966040_5 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000009754 237.0
HFD3_k127_6966040_6 Biotin-lipoyl like K02005 - - 0.00000000000000000000000000000000001405 149.0
HFD3_k127_6966040_7 - - - - 0.000000000000000000001534 97.0
HFD3_k127_6966040_8 Cytochrome c554 and c-prime - - - 0.000000000000000008443 84.0
HFD3_k127_6966040_9 phytol kinase activity - - - 0.0000000000000002121 87.0
HFD3_k127_6975034_0 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 496.0
HFD3_k127_6975034_1 PFAM 4Fe-4S K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 426.0
HFD3_k127_6975034_2 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 293.0
HFD3_k127_6975034_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K14986 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000003215 209.0
HFD3_k127_6975034_4 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000001251 209.0
HFD3_k127_6975034_5 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000002003 202.0
HFD3_k127_6975034_6 - - - - 0.00000000000000000000000000000000000000000001196 175.0
HFD3_k127_6975034_7 HEAT-like repeat - - - 0.000000000002576 74.0
HFD3_k127_6975034_9 Domain of unknown function (DUF4115) K15539 - - 0.00000223 53.0
HFD3_k127_6986975_0 Metal-dependent phosphohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 301.0
HFD3_k127_6986975_1 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002157 283.0
HFD3_k127_6986975_10 SMART Cold shock protein K03704 - - 0.0000000000000000000000000002768 114.0
HFD3_k127_6986975_11 Psort location Cytoplasmic, score - - - 0.0000000000000000000000025 105.0
HFD3_k127_6986975_12 - - - - 0.0000002518 54.0
HFD3_k127_6986975_13 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0004035 45.0
HFD3_k127_6986975_2 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000008576 240.0
HFD3_k127_6986975_3 oligoendopeptidase F K08602 - - 0.00000000000000000000000000000000000000000000000000000000000000000007791 253.0
HFD3_k127_6986975_4 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000047 206.0
HFD3_k127_6986975_5 - - - - 0.000000000000000000000000000000000000000000000000000000003624 210.0
HFD3_k127_6986975_6 Cupin - - - 0.0000000000000000000000000000000000000000000003163 172.0
HFD3_k127_6986975_7 - - - - 0.0000000000000000000000000000000000003242 149.0
HFD3_k127_6986975_8 4Fe-4S binding domain - - - 0.00000000000000000000000000000000113 132.0
HFD3_k127_6986975_9 IMG reference gene - - - 0.00000000000000000000000000004748 135.0
HFD3_k127_6987152_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004875 582.0
HFD3_k127_6987152_1 long-chain fatty acid transport protein K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007884 456.0
HFD3_k127_6987152_2 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004248 366.0
HFD3_k127_6987152_3 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 353.0
HFD3_k127_6987152_4 Glycosyltransferase family 9 (heptosyltransferase) K02841 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 319.0
HFD3_k127_6987152_5 6 heme-binding sites - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000442 318.0
HFD3_k127_6987152_6 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 304.0
HFD3_k127_6987152_7 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000003907 211.0
HFD3_k127_6987152_8 amine dehydrogenase activity - - - 0.000000000000000000000000003707 113.0
HFD3_k127_6987152_9 peptidase U32 - - - 0.000000000000003023 83.0
HFD3_k127_6991349_0 Alpha/beta hydrolase family K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 314.0
HFD3_k127_6991349_1 Radical SAM superfamily K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 306.0
HFD3_k127_6991349_2 Protein of unknown function (DUF3015) - - - 0.0000000000000000000000000000000000000000000000002515 180.0
HFD3_k127_6991349_3 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000000133 172.0
HFD3_k127_7000379_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.733e-257 806.0
HFD3_k127_7000379_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004321 341.0
HFD3_k127_7000379_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 336.0
HFD3_k127_7000379_3 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003604 295.0
HFD3_k127_7000379_4 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000008247 200.0
HFD3_k127_7000379_5 response regulator K02485 - - 0.000000000000000004791 88.0
HFD3_k127_7000379_6 PFAM YbbR family protein - - - 0.000000000000002389 79.0
HFD3_k127_7003102_0 Domain of unknown function (DUF1957) K16149 - 2.4.1.18 2.949e-259 808.0
HFD3_k127_7003102_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 561.0
HFD3_k127_7003102_2 FAD linked oxidase domain protein K00102,K00104 - 1.1.2.4,1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 494.0
HFD3_k127_7003102_3 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 468.0
HFD3_k127_7003102_4 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000000000000000000000000000000000000000003998 221.0
HFD3_k127_7003102_5 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000001172 158.0
HFD3_k127_7003102_6 Lysin motif - - - 0.0000000000000000000000000000000000001592 156.0
HFD3_k127_7003102_7 Domain of unknown function (DUF4912) K09942 - - 0.000000000000000000000000000000000001081 150.0
HFD3_k127_7003102_8 histidine kinase HAMP region domain protein K13598 - 2.7.13.3 0.00000000000000000003156 101.0
HFD3_k127_7003102_9 - - - - 0.0000000001375 63.0
HFD3_k127_7004654_0 SelR domain K07305,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008361 499.0
HFD3_k127_7004654_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006166 478.0
HFD3_k127_7004654_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008476 465.0
HFD3_k127_7004654_3 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 303.0
HFD3_k127_7004654_4 PFAM Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000001175 159.0
HFD3_k127_7004838_0 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335 - 1.6.5.3 4.961e-214 677.0
HFD3_k127_7004838_1 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 583.0
HFD3_k127_7004838_10 ubiE/COQ5 methyltransferase family - - - 0.0000000000179 68.0
HFD3_k127_7004838_11 - - - - 0.00002464 52.0
HFD3_k127_7004838_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 557.0
HFD3_k127_7004838_3 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006293 475.0
HFD3_k127_7004838_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 356.0
HFD3_k127_7004838_5 Belongs to the ompA family K12216 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001773 248.0
HFD3_k127_7004838_6 Divergent polysaccharide deacetylase K09798 - - 0.00000000000000000000000000000000000000000000000000006933 199.0
HFD3_k127_7004838_7 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000004257 174.0
HFD3_k127_7004838_8 Nitroreductase family - - - 0.00000000000000000000000000000000000009528 150.0
HFD3_k127_7004838_9 proteolysis K21140,K21147 - 2.7.7.80,2.8.1.11,3.13.1.6 0.00000000000000000000000001176 114.0
HFD3_k127_7010125_0 amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000008759 201.0
HFD3_k127_7010125_1 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000002598 157.0
HFD3_k127_7010125_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000004582 85.0
HFD3_k127_7010125_3 response regulator - - - 0.00000000007384 72.0
HFD3_k127_7013957_0 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 426.0
HFD3_k127_7013957_1 Protein of unknown function (DUF3641) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 346.0
HFD3_k127_7013957_2 Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001113 274.0
HFD3_k127_7013957_3 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000319 182.0
HFD3_k127_7013957_4 Membrane - - - 0.0000000000000000000006319 107.0
HFD3_k127_7013957_5 Flavin containing amine oxidoreductase K09516 - 1.3.99.23 0.00000002945 55.0
HFD3_k127_7014254_0 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008351 589.0
HFD3_k127_7014254_1 PAS domain K09155 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 470.0
HFD3_k127_7014254_2 Pfam SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002314 274.0
HFD3_k127_7014254_3 dUTP biosynthetic process K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000874 254.0
HFD3_k127_7014254_4 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000001586 201.0
HFD3_k127_7014254_5 - - - - 0.00000000000000000008232 91.0
HFD3_k127_7014254_6 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000000142 78.0
HFD3_k127_7014254_7 Tetratricopeptide repeat - - - 0.0005037 51.0
HFD3_k127_7025307_0 helicase K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005633 497.0
HFD3_k127_7025307_1 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004566 353.0
HFD3_k127_7025307_2 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 314.0
HFD3_k127_7025307_3 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000622 242.0
HFD3_k127_7025307_4 Sporulation and spore germination - - - 0.000000000000002723 84.0
HFD3_k127_7025307_5 cell wall hydrolase K01448 - 3.5.1.28 0.0000000000002783 81.0
HFD3_k127_7030511_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005406 452.0
HFD3_k127_7030511_1 methyltransferase - - - 0.0000000000000000000000000000000000002105 149.0
HFD3_k127_7030511_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000003539 113.0
HFD3_k127_7030511_3 Protein of unknown function DUF116 - - - 0.0000000000000000009158 96.0
HFD3_k127_7030511_4 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.00003126 50.0
HFD3_k127_7030511_5 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.0001134 46.0
HFD3_k127_7030511_6 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.0002177 44.0
HFD3_k127_7036061_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 8.173e-228 713.0
HFD3_k127_7036061_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001023 258.0
HFD3_k127_7036061_2 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.000000000000000000001285 99.0
HFD3_k127_7036061_3 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000008112 78.0
HFD3_k127_7036061_4 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.0002177 44.0
HFD3_k127_7036061_5 COG0350 Methylated DNA-protein cysteine methyltransferase K00567 - 2.1.1.63 0.0002798 43.0
HFD3_k127_7052523_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 4.081e-289 898.0
HFD3_k127_7052523_1 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005841 554.0
HFD3_k127_7052523_2 - - - - 0.000000000000000000000000000000000000000000004786 165.0
HFD3_k127_7079055_0 General secretory system II, protein E domain protein K02652 - - 1.364e-207 661.0
HFD3_k127_7079055_1 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 590.0
HFD3_k127_7079055_2 PFAM Histone deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 370.0
HFD3_k127_7079055_3 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000009831 194.0
HFD3_k127_7079055_4 - - - - 0.00000000000000000000001206 110.0
HFD3_k127_7079055_5 methyltransferase activity - - - 0.00000000000000000001084 100.0
HFD3_k127_7079055_7 Type II secretion system (T2SS), protein F K02653 - - 0.000001145 51.0
HFD3_k127_7079055_8 Glycosyl hydrolase family 3 N terminal domain - - - 0.0002279 49.0
HFD3_k127_7079055_9 Type II secretory pathway, pseudopilin - - - 0.000952 47.0
HFD3_k127_7082266_0 PLD-like domain K06131 - - 6.683e-203 640.0
HFD3_k127_7082266_1 Dehydrogenase K00004,K00008 - 1.1.1.14,1.1.1.303,1.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 543.0
HFD3_k127_7082266_10 1,4-alpha-glucan branching enzyme activity - - - 0.0000000000000000004803 91.0
HFD3_k127_7082266_11 Psort location Cytoplasmic, score - - - 0.00000000001631 66.0
HFD3_k127_7082266_12 Psort location Cytoplasmic, score - - - 0.00000002709 57.0
HFD3_k127_7082266_13 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000009475 49.0
HFD3_k127_7082266_2 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 527.0
HFD3_k127_7082266_3 short-chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 444.0
HFD3_k127_7082266_4 helix-turn-helix- domain containing protein, AraC type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004546 446.0
HFD3_k127_7082266_5 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 368.0
HFD3_k127_7082266_6 Activator of Hsp90 ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 338.0
HFD3_k127_7082266_7 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 325.0
HFD3_k127_7082266_8 Flavodoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001097 252.0
HFD3_k127_7082266_9 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000004266 207.0
HFD3_k127_7085973_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000733 562.0
HFD3_k127_7085973_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 413.0
HFD3_k127_7085973_2 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 351.0
HFD3_k127_7085973_3 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000001331 241.0
HFD3_k127_7085973_4 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000001526 216.0
HFD3_k127_7085973_5 D,d-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000000002548 205.0
HFD3_k127_7085973_6 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.000000000000000000000000000000000000000000000001028 177.0
HFD3_k127_7085973_7 Domain of unknown function (DUF374) K09778 - - 0.0000000000000000000000000000000000000043 153.0
HFD3_k127_7085973_8 Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c - GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - 0.00000000000000000003402 96.0
HFD3_k127_7102383_0 Glycogen debranching enzyme - - - 0.0 1559.0
HFD3_k127_7102383_1 Glucose dehydrogenase C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 577.0
HFD3_k127_7102383_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001998 259.0
HFD3_k127_7102383_3 PFAM Bile acid sodium symporter K03453 - - 0.00000000000000000000000000000000000000006432 162.0
HFD3_k127_7102383_4 - - - - 0.0000000000000000000000000000000009607 139.0
HFD3_k127_7102383_6 - - - - 0.00000001231 59.0
HFD3_k127_7102383_7 - - - - 0.0000003193 56.0
HFD3_k127_7126018_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 287.0
HFD3_k127_7126018_1 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000001888 269.0
HFD3_k127_7126018_2 tRNA pseudouridylate synthase B C-terminal domain K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000002482 196.0
HFD3_k127_7126018_3 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000017 130.0
HFD3_k127_7126018_4 Protein of unknown function (DUF503) K09764 - - 0.000000000000000000000000001487 113.0
HFD3_k127_7126018_5 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.000001412 49.0
HFD3_k127_7134446_0 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 598.0
HFD3_k127_7134446_1 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007508 406.0
HFD3_k127_7134446_2 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000006676 222.0
HFD3_k127_7134446_3 Protein of unknown function (DUF2905) - - - 0.00000000000000415 76.0
HFD3_k127_7164365_0 PFAM V-type ATPase 116 kDa K02123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 572.0
HFD3_k127_7164365_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044464,GO:0044769,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1902600 3.6.3.14,3.6.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004761 558.0
HFD3_k127_7164365_10 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.0000000000000000000000000000000000002722 148.0
HFD3_k127_7164365_12 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0000000000000000000000000000004436 129.0
HFD3_k127_7164365_13 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.000000000000000000000000002716 114.0
HFD3_k127_7164365_14 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.00000000000000000000000002297 112.0
HFD3_k127_7164365_15 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.000000000000000000005552 94.0
HFD3_k127_7164365_16 Rhodanese Homology Domain - - - 0.000000000000000001345 89.0
HFD3_k127_7164365_17 Integrase core domain - - - 0.000000713 53.0
HFD3_k127_7164365_2 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000874 506.0
HFD3_k127_7164365_3 PAS domain K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006202 374.0
HFD3_k127_7164365_4 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006038 286.0
HFD3_k127_7164365_5 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000966 279.0
HFD3_k127_7164365_6 ATP synthase alpha/beta family, nucleotide-binding domain K02118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005922 242.0
HFD3_k127_7164365_7 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002633 241.0
HFD3_k127_7164365_8 alpha beta - - - 0.00000000000000000000000000000000000000000000000222 188.0
HFD3_k127_7164365_9 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000005938 177.0
HFD3_k127_7166842_0 Ompa motb domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005015 275.0
HFD3_k127_7166842_1 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000007219 209.0
HFD3_k127_7166842_2 Ompa motb domain protein - - - 0.0000000000000000000000000000000000000000000000001024 205.0
HFD3_k127_7166842_3 Conserved repeat domain - - - 0.00000000000000000000000000000000001865 158.0
HFD3_k127_7166842_4 Ompa motb domain protein - - - 0.0000000000000004237 87.0
HFD3_k127_7166842_5 Transposase - - - 0.00000000001261 65.0
HFD3_k127_7176839_0 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 409.0
HFD3_k127_7176839_1 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 305.0
HFD3_k127_7176839_2 - - - - 0.0000000000000000000000000000000000000000000000000000000004672 206.0
HFD3_k127_7176839_3 Ferritin-like domain K03594 - 1.16.3.1 0.00000000000000000000000000000000001304 139.0
HFD3_k127_7176839_4 cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000002517 99.0
HFD3_k127_7176839_5 electron transfer activity K05337,K17247 - - 0.000000000000000000008002 93.0
HFD3_k127_7176839_6 Protein of unknown function, DUF488 - - - 0.0000000000000000003705 88.0
HFD3_k127_7176839_7 Polysaccharide biosynthesis/export protein - - - 0.0000000000000000696 82.0
HFD3_k127_7176839_8 part of a sulfur-relay system K11179 - - 0.000000001637 60.0
HFD3_k127_7177087_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 5.737e-233 733.0
HFD3_k127_7177087_1 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 9.116e-199 642.0
HFD3_k127_7177087_10 Cell surface protein - - - 0.000000000000000000000168 113.0
HFD3_k127_7177087_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008737 499.0
HFD3_k127_7177087_3 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404 452.0
HFD3_k127_7177087_4 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 347.0
HFD3_k127_7177087_5 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005848 274.0
HFD3_k127_7177087_6 CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001536 269.0
HFD3_k127_7177087_7 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000001313 203.0
HFD3_k127_7177087_8 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.000000000000000000000000000000000000000000000007155 181.0
HFD3_k127_7177087_9 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.0000000000000000000000000000000000988 137.0
HFD3_k127_71896_0 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009077 490.0
HFD3_k127_71896_1 TPR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 409.0
HFD3_k127_71896_2 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000001531 220.0
HFD3_k127_71896_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000006322 217.0
HFD3_k127_71896_4 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000002367 181.0
HFD3_k127_71896_5 cheY-homologous receiver domain - - - 0.0000000000001523 74.0
HFD3_k127_7199467_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 523.0
HFD3_k127_7199467_1 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005482 277.0
HFD3_k127_7201711_0 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000001763 222.0
HFD3_k127_7201711_1 phosphorelay signal transduction system - - - 0.0005655 50.0
HFD3_k127_7201808_0 trisaccharide binding K03556 - - 0.000000000000000000000000000001226 133.0
HFD3_k127_7201808_1 Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria - - - 0.000000000000000001863 88.0
HFD3_k127_7201808_2 Protein of unknown function, DUF255 K04084 - 1.8.1.8 0.000000001061 64.0
HFD3_k127_7201808_3 Bacterial extracellular solute-binding proteins, family 3 K02030 - - 0.000006658 50.0
HFD3_k127_7208627_0 Belongs to the peptidase M16 family K07263 - - 0.0 1069.0
HFD3_k127_7208627_1 Aconitase C-terminal domain K01681 - 4.2.1.3 0.0 1051.0
HFD3_k127_7208627_10 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.0000000000000000000000000000000000000000000000000000000003453 210.0
HFD3_k127_7208627_11 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000000000000000002764 177.0
HFD3_k127_7208627_12 Protein of unknown function (DUF4239) - - - 0.0000000000000001533 84.0
HFD3_k127_7208627_2 Belongs to the TPP enzyme family K01652 - 2.2.1.6 1.149e-246 771.0
HFD3_k127_7208627_3 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 6.683e-213 670.0
HFD3_k127_7208627_4 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009304 566.0
HFD3_k127_7208627_5 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004155 534.0
HFD3_k127_7208627_6 PFAM Aldehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 539.0
HFD3_k127_7208627_7 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261 - 1.4.1.2,1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 383.0
HFD3_k127_7208627_8 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000002281 213.0
HFD3_k127_7208627_9 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000003171 209.0
HFD3_k127_7216962_0 all-trans-retinol 13,14-reductase activity K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 567.0
HFD3_k127_7216962_1 glyoxalase III activity K13653 - - 0.0000000000000000000000000000000000000000000000000000000000004303 213.0
HFD3_k127_7216962_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000008261 169.0
HFD3_k127_7216962_3 methyltransferase - - - 0.00000000000000000000000000000000000005834 143.0
HFD3_k127_7216962_4 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000007635 139.0
HFD3_k127_7216962_5 Uncharacterized conserved protein (DUF2277) - - - 0.0000000000000000000000000000001169 125.0
HFD3_k127_7216962_6 Spermine/spermidine synthase domain - - - 0.00000000000000000000000001242 113.0
HFD3_k127_7216962_7 Acetyltransferase (GNAT) family - - - 0.00000462 48.0
HFD3_k127_7224785_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 562.0
HFD3_k127_7224785_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 449.0
HFD3_k127_7224785_2 UPF0126 domain - - - 0.0000000000000000000000000000000000000000000000000000008985 198.0
HFD3_k127_7224785_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000005242 173.0
HFD3_k127_7224785_4 TIGRFAM 4-oxalocrotonate tautomerase family enzyme K01821 - 5.3.2.6 0.0000000000000000000000000001956 116.0
HFD3_k127_7224785_5 NeuB family K03856,K04516 - 2.5.1.54,5.4.99.5 0.00000000000000000004177 94.0
HFD3_k127_7230361_0 DEAD_2 K10844 - 3.6.4.12 0.0 1058.0
HFD3_k127_7230361_1 Lipocalin-like domain K03098 - - 0.000000000000000000000000000000000000000000000000000005468 194.0
HFD3_k127_7230361_10 endonuclease distantly related to archaeal Holliday junction resolvase and Mrr-like restriction enzymes K07448 - - 0.0009065 44.0
HFD3_k127_7230361_2 AMP binding - - - 0.00000000000000000000000000000000000000000000006379 181.0
HFD3_k127_7230361_3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.00000000000000000000000000000000000000000003338 168.0
HFD3_k127_7230361_4 - - - - 0.000000000000000000000000000000000000001783 151.0
HFD3_k127_7230361_5 - - - - 0.0000000000000002659 85.0
HFD3_k127_7230361_6 Phospholipase_D-nuclease N-terminal - - - 0.0000000005059 63.0
HFD3_k127_7230361_7 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000001318 55.0
HFD3_k127_7230361_9 Topoisomerase DNA binding C4 zinc finger K07448 - - 0.00003666 47.0
HFD3_k127_7240970_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 1.56e-267 837.0
HFD3_k127_7240970_1 Biotin-lipoyl like K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009303 380.0
HFD3_k127_7240970_2 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 368.0
HFD3_k127_7240970_3 transcriptional regulator - GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000001591 194.0
HFD3_k127_7240970_4 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.0000001454 56.0
HFD3_k127_7287416_0 domain, Protein K12373 - 3.2.1.52 0.0 1243.0
HFD3_k127_7287416_1 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 499.0
HFD3_k127_7287416_10 PFAM CBS domain - - - 0.0000000000000000000000000000000005881 138.0
HFD3_k127_7287416_11 Rubredoxin - - - 0.00000000000000000000002324 99.0
HFD3_k127_7287416_12 TIGRFAM cytochrome oxidase maturation protein, cbb3-type - - - 0.0000000001891 63.0
HFD3_k127_7287416_2 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 466.0
HFD3_k127_7287416_3 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005849 466.0
HFD3_k127_7287416_4 PFAM ABC transporter K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 454.0
HFD3_k127_7287416_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 317.0
HFD3_k127_7287416_6 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000036 250.0
HFD3_k127_7287416_7 HPP family K07168 - - 0.00000000000000000000000000000000000000000000000000000000000000000009155 235.0
HFD3_k127_7287416_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000141 219.0
HFD3_k127_7287416_9 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000005834 156.0
HFD3_k127_7289233_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 381.0
HFD3_k127_7289233_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 344.0
HFD3_k127_7297943_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 368.0
HFD3_k127_7297943_1 Protein of unknown function (DUF3494) - - - 0.0000000000000000000000000000000000000001019 169.0
HFD3_k127_7297943_2 Transcriptional regulator, MerR family K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000008739 133.0
HFD3_k127_7297943_3 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0000000000000000000000000000000226 130.0
HFD3_k127_7297943_4 lyase activity - - - 0.000000000000000000000000008838 118.0
HFD3_k127_7306939_0 Bacterial DNA polymerase III alpha subunit K02337 - 2.7.7.7 2.46e-282 888.0
HFD3_k127_7306939_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 325.0
HFD3_k127_7306939_2 Nitroreductase family K04719 - 1.13.11.79 0.0000000000000000000000000000000000000000000000000000000000001288 216.0
HFD3_k127_7306939_3 - - - - 0.000000000000000000000000000000000007099 147.0
HFD3_k127_7306939_4 - - - - 0.000004945 53.0
HFD3_k127_7328923_0 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 331.0
HFD3_k127_7328923_1 Protein of unknown function DUF89 K09116 - - 0.0000000000000000000000000000000000000000000000000000000002799 214.0
HFD3_k127_7328923_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000009727 201.0
HFD3_k127_7328923_3 Telomere recombination K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000004629 173.0
HFD3_k127_7358822_0 Efflux ABC transporter, permease protein K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000001202 248.0
HFD3_k127_7358822_1 Part of the ABC transporter complex LolCDE involved in the translocation of K02003,K09810 - - 0.0000000000000000000000000000000000000000000000008931 183.0
HFD3_k127_7358822_2 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.000000000004329 67.0
HFD3_k127_7358822_3 NosL K19342 - - 0.0000000002473 66.0
HFD3_k127_7358822_4 protein N-acetylglucosaminyltransferase activity - - - 0.000000003705 65.0
HFD3_k127_7358822_5 Domain of unknown function (DUF4418) - - - 0.0000002443 58.0
HFD3_k127_7358822_6 TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - 0.00000811 58.0
HFD3_k127_7362004_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004064 573.0
HFD3_k127_7362004_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 404.0
HFD3_k127_7362004_2 Serine acetyltransferase, N-terminal K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005819 284.0
HFD3_k127_7362004_3 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001147 267.0
HFD3_k127_7362004_4 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000000000000000000000006915 235.0
HFD3_k127_7362004_5 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000344 213.0
HFD3_k127_7362004_6 inositol monophosphate 1-phosphatase activity K01082,K01092 - 3.1.3.25,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000004036 214.0
HFD3_k127_7362004_7 OsmC-like protein K07397 - - 0.00000000000000000000000000000000000000000001519 166.0
HFD3_k127_7379220_0 COGs COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 400.0
HFD3_k127_7379220_1 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005714 308.0
HFD3_k127_7379220_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 306.0
HFD3_k127_7379220_3 imidazoleglycerol-phosphate dehydratase activity K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000003274 263.0
HFD3_k127_7379220_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000002089 102.0
HFD3_k127_7461708_0 Elongation factor Tu domain 2 K02355 - - 2.442e-227 724.0
HFD3_k127_7461708_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.617e-208 662.0
HFD3_k127_7461708_2 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000552 526.0
HFD3_k127_7461708_3 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 417.0
HFD3_k127_7461708_4 Peptidase M16 domain protein K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005802 380.0
HFD3_k127_7461708_5 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.0000000000000000000000000000000000000000000000000004823 187.0
HFD3_k127_7461708_6 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000002381 117.0
HFD3_k127_7461708_7 - - - - 0.0000000000000000000001099 101.0
HFD3_k127_7461708_8 Positive regulator of sigma(E), RseC/MucC K03803 - - 0.00000000000000005855 86.0
HFD3_k127_7476003_0 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 542.0
HFD3_k127_7476003_1 serine-type endopeptidase activity K04772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007023 483.0
HFD3_k127_7476003_10 Psort location Periplasmic, score 9.44 - - - 0.0000005909 63.0
HFD3_k127_7476003_11 - - - - 0.000001606 50.0
HFD3_k127_7476003_2 Protein of unknown function (DUF3443) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 426.0
HFD3_k127_7476003_3 lysozyme activity K07273 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002831 262.0
HFD3_k127_7476003_4 Membrane K08984 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000002138 238.0
HFD3_k127_7476003_5 PFAM Isochorismatase K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000000000000007235 202.0
HFD3_k127_7476003_6 monooxygenase activity - - - 0.000000000000000000000000000000000000000000000000000006085 193.0
HFD3_k127_7476003_7 Protein of unknown function (DUF2844) - - - 0.000000000000000000000000000000000000000000000007006 176.0
HFD3_k127_7476003_8 Protein of unknown function (DUF2845) - - - 0.000000000000000216 83.0
HFD3_k127_7476003_9 PEGA domain - - - 0.00000000003206 72.0
HFD3_k127_7480650_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 5.249e-194 617.0
HFD3_k127_7480650_1 S-layer homology domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006877 344.0
HFD3_k127_7480650_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 346.0
HFD3_k127_7480650_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008858 261.0
HFD3_k127_7480650_4 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000009449 245.0
HFD3_k127_7480650_5 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000000004281 200.0
HFD3_k127_7480650_6 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000000001959 138.0
HFD3_k127_7480650_7 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000008316 128.0
HFD3_k127_7480650_8 Transglutaminase-like superfamily - - - 0.000000000000000000002075 109.0
HFD3_k127_7480650_9 - - - - 0.0000000001202 65.0
HFD3_k127_7610526_0 Domain of unknown function (DUF892) - - - 0.00000000000000000000000000000000004305 139.0
HFD3_k127_7610526_1 Psort location Cytoplasmic, score - - - 0.0000000001016 70.0
HFD3_k127_7660362_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 356.0
HFD3_k127_7660362_1 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 339.0
HFD3_k127_7660362_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009315 337.0
HFD3_k127_7660362_3 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000002853 275.0
HFD3_k127_7660362_5 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000001015 122.0
HFD3_k127_7660362_6 NmrA-like family - - - 0.0000002493 54.0
HFD3_k127_7716709_0 Putative zinc- or iron-chelating domain - - - 0.00000000000000000000000000000000000000000000000000003532 196.0
HFD3_k127_7716709_1 anaerobic respiration - - - 0.000000000000000000000000000175 125.0
HFD3_k127_7736183_0 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 351.0
HFD3_k127_7736183_1 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 327.0
HFD3_k127_7736183_2 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005736 306.0
HFD3_k127_7736183_3 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004043 255.0
HFD3_k127_7736183_4 transcriptional regulator - - - 0.00000000000000000000000000000000000000001651 160.0
HFD3_k127_7736183_5 - - - - 0.000000000000000000000000002824 120.0
HFD3_k127_7736183_6 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000001451 58.0
HFD3_k127_7740578_0 Nitronate monooxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 537.0
HFD3_k127_7740578_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 459.0
HFD3_k127_7740578_2 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005049 285.0
HFD3_k127_7740578_3 Putative TM nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000004472 199.0
HFD3_k127_7740578_4 Zinc dependent phospholipase C - - - 0.000000000000000000001064 96.0
HFD3_k127_7747263_0 POT family K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 509.0
HFD3_k127_7747263_1 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000001301 168.0
HFD3_k127_7747263_3 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000006427 133.0
HFD3_k127_778424_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 445.0
HFD3_k127_778424_1 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 291.0
HFD3_k127_778424_2 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007719 254.0
HFD3_k127_778424_3 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000001503 193.0
HFD3_k127_778424_4 Protein of unknown function (DUF1329) - - - 0.00000000000000000000000000000004449 138.0
HFD3_k127_778424_5 Sh3 type 3 domain protein - - - 0.00000000000000002525 95.0
HFD3_k127_780126_0 HlyD family secretion protein K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009744 310.0
HFD3_k127_780126_1 Belongs to the RtcB family K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000002103 214.0
HFD3_k127_780126_2 nuclease K01174 GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 3.1.31.1 0.0000000000000000000000000000000000000000006265 163.0
HFD3_k127_784603_0 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000355 526.0
HFD3_k127_784682_0 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005153 313.0
HFD3_k127_784682_1 Domain of unknown function (DUF1848) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003972 268.0
HFD3_k127_784682_2 HlyD membrane-fusion protein of T1SS K03543 - - 0.0000002405 54.0
HFD3_k127_786705_0 Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 420.0
HFD3_k127_786705_1 4Fe-4S dicluster domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 360.0
HFD3_k127_786705_2 Cytochrome c3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 321.0
HFD3_k127_786705_3 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008369 284.0
HFD3_k127_786705_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001244 280.0
HFD3_k127_786705_5 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000005422 240.0
HFD3_k127_786705_6 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000001083 209.0
HFD3_k127_786705_7 regulation of translation K05788 - - 0.0000000000000000000000000001564 117.0
HFD3_k127_786705_8 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.000000000000001155 79.0
HFD3_k127_786705_9 PFAM Cytochrome c, bacterial - - - 0.0000000000533 70.0
HFD3_k127_786849_0 Putative diguanylate phosphodiesterase - - - 1.832e-200 657.0
HFD3_k127_786849_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 612.0
HFD3_k127_786849_10 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000476 295.0
HFD3_k127_786849_11 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005866 276.0
HFD3_k127_786849_12 Flavodoxin-like fold K19784 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009588 259.0
HFD3_k127_786849_13 cytidylate kinase activity K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000002806 235.0
HFD3_k127_786849_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000002545 233.0
HFD3_k127_786849_15 Uncharacterized conserved protein (DUF2249) - - - 0.00000000000000000000000000785 111.0
HFD3_k127_786849_16 PFAM VanZ - - - 0.00000000000000000000000003488 112.0
HFD3_k127_786849_17 - - - - 0.000000000000000000007711 100.0
HFD3_k127_786849_18 PFAM CBS domain containing protein - - - 0.00000000000004896 78.0
HFD3_k127_786849_19 Evidence 4 Homologs of previously reported genes of - - - 0.0000000001189 67.0
HFD3_k127_786849_2 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 566.0
HFD3_k127_786849_20 electron transfer activity K05337,K17247 - - 0.0000000009147 65.0
HFD3_k127_786849_3 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 464.0
HFD3_k127_786849_4 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 468.0
HFD3_k127_786849_5 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 455.0
HFD3_k127_786849_6 Ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 450.0
HFD3_k127_786849_7 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006609 435.0
HFD3_k127_786849_8 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 387.0
HFD3_k127_786849_9 Belongs to the SfsA family K06206 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 389.0
HFD3_k127_787729_0 AefR-like transcriptional repressor, C-terminal region - - - 0.000000000000000000000000000001221 128.0
HFD3_k127_787729_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000003467 115.0
HFD3_k127_787729_2 COG3278 Cbb3-type cytochrome oxidase, subunit 1 - - - 0.000000000000000000003294 98.0
HFD3_k127_787729_3 - - - - 0.0000008969 51.0
HFD3_k127_795020_0 glycosyl transferase family 2 K21349 - 2.4.1.268 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005747 566.0
HFD3_k127_795020_1 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 GO:0003674,GO:0005215,GO:0005451,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035725,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005101 544.0
HFD3_k127_795020_2 COG0463 Glycosyltransferases involved in cell wall biogenesis K13693 - 2.4.1.266 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006595 521.0
HFD3_k127_795020_3 hydroxypyruvate reductase K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005083 456.0
HFD3_k127_795020_4 response to heat K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 430.0
HFD3_k127_795020_5 haloacid dehalogenase-like hydrolase K07026 - 3.1.3.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001892 273.0
HFD3_k127_795020_6 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000000000000006742 245.0
HFD3_k127_795020_7 - - - - 0.0000000000000000000000000000000000000000008407 160.0
HFD3_k127_795020_8 transmembrane transport - - - 0.00000000000000000000000000004626 125.0
HFD3_k127_795020_9 translation initiation factor activity K03646 - - 0.000000000000000000000003345 106.0
HFD3_k127_795063_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 3.013e-307 958.0
HFD3_k127_795063_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 327.0
HFD3_k127_795063_2 Lytic transglycolase K03642 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008035 271.0
HFD3_k127_795063_3 ACT domain protein - - - 0.000000008854 62.0
HFD3_k127_795063_4 Rhodanese domain protein - - - 0.0000003262 52.0
HFD3_k127_797527_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 526.0
HFD3_k127_797527_1 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004529 275.0
HFD3_k127_797527_2 PFAM glucosamine galactosamine-6-phosphate isomerase K01057 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000001534 241.0
HFD3_k127_797527_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000004899 204.0
HFD3_k127_800065_0 SMART Diguanylate phosphodiesterase - - - 2.1e-322 1001.0
HFD3_k127_800065_1 protein-glutamate methylesterase activity K03412,K03413,K13924 - 2.1.1.80,3.1.1.61,3.5.1.44 1.741e-313 990.0
HFD3_k127_800065_10 - - - - 0.00000000000000002437 82.0
HFD3_k127_800065_11 CsbD-like - - - 0.00000000000000005979 84.0
HFD3_k127_800065_12 BON domain - - - 0.0000001453 53.0
HFD3_k127_800065_13 - - - - 0.0002964 44.0
HFD3_k127_800065_14 Winged helix-turn helix - - - 0.0003381 48.0
HFD3_k127_800065_2 PFAM sigma-54 factor interaction domain-containing protein K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 507.0
HFD3_k127_800065_3 bacterial OsmY and nodulation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006825 289.0
HFD3_k127_800065_4 Histidine kinase - - - 0.0000000000000000000000000000000000000344 154.0
HFD3_k127_800065_5 - - - - 0.0000000000000000000000000000003534 126.0
HFD3_k127_800065_6 - - - - 0.00000000000000000000000000034 115.0
HFD3_k127_800065_7 Protein of unknown function (DUF3309) - - - 0.00000000000000000007383 90.0
HFD3_k127_800065_8 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000868 86.0
HFD3_k127_800065_9 ATP-binding region ATPase domain protein - - - 0.00000000000000002198 92.0
HFD3_k127_805895_0 Pfam Anion-transporting ATPase K01551,K19171 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004689 276.0
HFD3_k127_805895_1 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000006381 226.0
HFD3_k127_805895_2 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000001579 220.0
HFD3_k127_811013_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 521.0
HFD3_k127_811013_1 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 333.0
HFD3_k127_811013_2 Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 294.0
HFD3_k127_811013_3 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000006211 261.0
HFD3_k127_811013_4 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000002225 183.0
HFD3_k127_811013_5 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000001737 147.0
HFD3_k127_821431_0 Molybdopterin oxidoreductase Fe4S4 domain K00336 - 1.6.5.3 0.0 1189.0
HFD3_k127_821431_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 480.0
HFD3_k127_821431_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 291.0
HFD3_k127_821431_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000006873 262.0
HFD3_k127_823354_0 Domain of unknown function (DUF3943) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 530.0
HFD3_k127_823354_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004085 274.0
HFD3_k127_823354_2 - - - - 0.00000000000000000000003492 113.0
HFD3_k127_823354_3 - - - - 0.000000000000000000002878 94.0
HFD3_k127_823354_4 CsbD-like - - - 0.0000001332 55.0
HFD3_k127_823354_5 - - - - 0.0000003243 53.0
HFD3_k127_834214_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007998 528.0
HFD3_k127_834214_1 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 371.0
HFD3_k127_834214_2 ABC 3 transport family K09816 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 341.0
HFD3_k127_834214_3 PFAM ABC transporter related K09817 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 302.0
HFD3_k127_834214_4 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000000000000000004171 115.0
HFD3_k127_834214_5 Putative transposase DNA-binding domain - - - 0.000000000000001003 80.0
HFD3_k127_83707_0 Transglycosylase K05366 GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009997 582.0
HFD3_k127_83707_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 316.0
HFD3_k127_83707_2 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000001448 201.0
HFD3_k127_83707_3 PFAM GGDEF domain containing protein - - - 0.000000000000000009943 92.0
HFD3_k127_83707_4 Phosphate starvation-inducible protein PhoH K06217 - - 0.000002063 53.0
HFD3_k127_845405_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960,K20810 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31,3.5.4.40 0.000000000000000000000000000000000000000000000000000000000000000001259 243.0
HFD3_k127_845405_1 Glycosyl transferase family 41 K09667 - 2.4.1.255 0.000000000000000000000000001211 123.0
HFD3_k127_845405_2 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.000000000000000000000000005113 113.0
HFD3_k127_845405_3 Pfam:N_methyl_2 K02650 - - 0.0000000000000000000000006731 111.0
HFD3_k127_845405_4 Pfam:N_methyl_2 K02650 - - 0.000000000000000000008984 100.0
HFD3_k127_847495_0 PFAM Radical SAM domain protein K02585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 320.0
HFD3_k127_847495_1 Dinucleotide-utilizing enzyme possibly involved in molybdopterin or thiamin biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004444 256.0
HFD3_k127_847495_10 Predicted permease K07089 - - 0.000000000000641 69.0
HFD3_k127_847495_2 Nitrogen regulatory protein P-II K02590 - - 0.00000000000000000000000000000000000000000000000000000000006658 206.0
HFD3_k127_847495_3 Nitrogen regulatory protein P-II K02589 - - 0.00000000000000000000000000000000000000000000000000002076 188.0
HFD3_k127_847495_4 Dinitrogenase iron-molybdenum cofactor K02596 - - 0.000000000000000000000000000000000000000000006733 167.0
HFD3_k127_847495_6 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000005123 141.0
HFD3_k127_847495_7 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000008731 130.0
HFD3_k127_847495_8 3'-5' exonuclease - - - 0.00000000000000000000000000000002365 134.0
HFD3_k127_847495_9 Nitrogenase component 1 type Oxidoreductase K02587 - - 0.0000000000000000000004061 97.0
HFD3_k127_851398_0 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004489 392.0
HFD3_k127_851398_1 - - - - 0.00000000000009832 73.0
HFD3_k127_851398_2 - - - - 0.0000000000341 73.0
HFD3_k127_865570_0 Pyridoxal-phosphate dependent enzyme K06001 - 4.2.1.20 2.458e-219 687.0
HFD3_k127_865570_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 565.0
HFD3_k127_865570_10 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.00000000000000000000000000000000009748 134.0
HFD3_k127_865570_11 Smr domain - - - 0.00000000000000000000001548 108.0
HFD3_k127_865570_12 - - - - 0.0000000000001501 78.0
HFD3_k127_865570_2 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 489.0
HFD3_k127_865570_3 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 416.0
HFD3_k127_865570_4 COG1194 A G-specific DNA glycosylase K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 334.0
HFD3_k127_865570_5 radical SAM K06871 - - 0.00000000000000000000000000000000000000000000000000000000002915 217.0
HFD3_k127_865570_6 belongs to the CobB CobQ family K06873 - - 0.000000000000000000000000000000000000000000000005449 175.0
HFD3_k127_865570_7 Transcriptional - - - 0.000000000000000000000000000000000025 136.0
HFD3_k127_865570_8 C4-type zinc ribbon domain K07164 - - 0.00000000000000000000000000000000003153 143.0
HFD3_k127_865570_9 PFAM ribonuclease H K03469,K06864 - 3.1.26.4 0.00000000000000000000000000000000008183 139.0
HFD3_k127_874219_0 cytochrome complex assembly - - - 0.00000000000000000000000000000000000000000000000000000007223 204.0
HFD3_k127_874219_1 regulation of translation K03530 - - 0.00000000000000000000000000000000000001675 145.0
HFD3_k127_874219_2 Outer membrane lipoprotein Slp family K07285 - - 0.0000000000000000000000000004542 120.0
HFD3_k127_874219_4 identical protein binding K07285 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0016020,GO:0019867,GO:0042802 - 0.00000002527 58.0
HFD3_k127_88523_0 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 610.0
HFD3_k127_88523_1 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000929 168.0
HFD3_k127_88523_2 Methyltransferase domain - - - 0.00000000000000000000000000000000007499 142.0
HFD3_k127_88523_3 DNA-binding transcription factor activity K03655,K03892,K21903 - 3.6.4.12 0.0000000000000000000002249 101.0
HFD3_k127_88523_4 Sulfur reduction protein DsrE - - - 0.000000003289 63.0
HFD3_k127_88735_0 Protein of unknown function (DUF3604) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005873 465.0
HFD3_k127_88735_1 COG3335 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000000001253 197.0
HFD3_k127_88735_2 Transposase - - - 0.000000000000000000000000000000000000000000000000000000805 198.0
HFD3_k127_88735_3 phosphorelay signal transduction system - - - 0.00000000000000000000000007433 113.0
HFD3_k127_88735_4 Transposase - - - 0.000000000000000000000002261 108.0
HFD3_k127_907046_0 Bacterial Ig-like domain 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 577.0
HFD3_k127_907046_1 NADPH-quinone reductase (modulator of drug activity B) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009277 304.0
HFD3_k127_907046_2 PFAM aldo keto reductase K07079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001418 277.0
HFD3_k127_907046_3 peptidase U32 - - - 0.00000000000000000000000000000000000000000000000000000000000003022 216.0
HFD3_k127_907046_4 - - - - 0.0000000000000000000000000000026 133.0
HFD3_k127_907046_5 - - - - 0.0000000000000000000000000003354 115.0
HFD3_k127_907046_6 - - - - 0.00000000000000000003285 96.0
HFD3_k127_907046_8 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07285 - - 0.00000006439 56.0
HFD3_k127_907046_9 CGGC - - - 0.000001216 50.0
HFD3_k127_913230_0 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 439.0
HFD3_k127_913230_1 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 406.0
HFD3_k127_93951_0 Heat shock 70 kDa protein K04043 - - 4.381e-301 934.0
HFD3_k127_93951_1 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000005678 128.0
HFD3_k127_93951_2 DnaJ C terminal domain K09510 - - 0.0000000003413 61.0
HFD3_k127_958818_0 Domain of unknown function (DUF4445) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 602.0
HFD3_k127_958818_2 PFAM NLP P60 protein - - - 0.000000000000000000000000001779 117.0
HFD3_k127_97379_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 8.969e-209 657.0
HFD3_k127_97379_1 Histidine kinase - - - 0.000000000002266 74.0
HFD3_k127_97379_2 Diguanylate cyclase - - - 0.0009216 50.0