Overview

ID MAG01696
Name HFD3_bin.4
Sample SMP0045
Taxonomy
Kingdom Bacteria
Phylum Chloroflexota
Class Limnocylindria
Order P2-11E
Family P2-11E
Genus CF-39
Species
Assembly information
Completeness (%) 75.48
Contamination (%) 1.91
GC content (%) 70.0
N50 (bp) 6,245
Genome size (bp) 2,167,505

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2208

Gene name Description KEGG GOs EC E-value Score Sequence
HFD3_k127_1034606_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000000000000000000000000000000000000000000000000001103 214.0
HFD3_k127_1034606_1 DHHA1 domain K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000001918 185.0
HFD3_k127_1034606_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000007349 131.0
HFD3_k127_1034606_3 Ribosome-binding factor A K02834 - - 0.000000000000000000001785 105.0
HFD3_k127_1042076_0 PFAM NMT1 THI5 like domain protein K02051,K15598 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008806 299.0
HFD3_k127_1042076_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000007533 230.0
HFD3_k127_1042076_2 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000001469 213.0
HFD3_k127_1042076_3 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000002186 203.0
HFD3_k127_1042076_4 DEAD DEAH box K03724 - - 0.00000000000000000000000000000000000001051 147.0
HFD3_k127_1042076_5 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000009441 61.0
HFD3_k127_1081621_0 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000001047 251.0
HFD3_k127_1081621_1 inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000002538 166.0
HFD3_k127_1081621_2 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.000000000000000000000000000000000001276 144.0
HFD3_k127_1088323_0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001554 283.0
HFD3_k127_1088323_1 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000002326 210.0
HFD3_k127_1088323_2 Tetrapyrrole (Corrin/Porphyrin) Methylases K02428,K02499 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 0.000000000000000000000000000000000000000000000000000001775 203.0
HFD3_k127_1088323_3 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000000000000001433 102.0
HFD3_k127_1104739_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000901 396.0
HFD3_k127_1104739_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K14091 - 1.6.5.3 0.0000000000000000000322 103.0
HFD3_k127_1132455_0 DNA primase, small subunit K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 302.0
HFD3_k127_1132455_1 ATP dependent DNA ligase C terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003599 293.0
HFD3_k127_1132455_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000006766 239.0
HFD3_k127_1132455_3 Domain of unknown function (DUF4173) - - - 0.0000000008937 66.0
HFD3_k127_1154393_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 6.142e-227 715.0
HFD3_k127_1154393_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000003355 102.0
HFD3_k127_1188598_0 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000002734 195.0
HFD3_k127_1188598_1 COG0491 Zn-dependent hydrolases, including glyoxylases K01069 - 3.1.2.6 0.0000000000000000000000000000000000461 138.0
HFD3_k127_1205352_0 Response regulator receiver K02483 - - 0.000000000000000000000000000000000000000000000000001367 194.0
HFD3_k127_1205352_1 protein histidine kinase activity - - - 0.00000000000000000000000000000005755 132.0
HFD3_k127_1205352_2 PFAM Type II secretion system protein E K02652 - - 0.00007211 49.0
HFD3_k127_1215957_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 5.884e-244 781.0
HFD3_k127_1215957_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 553.0
HFD3_k127_1215957_10 - - - - 0.00001374 57.0
HFD3_k127_1215957_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 513.0
HFD3_k127_1215957_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002776 260.0
HFD3_k127_1215957_4 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000009521 222.0
HFD3_k127_1215957_5 Belongs to the phosphoglycerate mutase family K02226,K22305 - 3.1.3.3,3.1.3.73 0.000000000000000000000001347 112.0
HFD3_k127_1215957_6 phosphatase activity K05967 - - 0.0000000000000000005476 100.0
HFD3_k127_1215957_7 CAAX protease self-immunity K07052 - - 0.000000000000001028 89.0
HFD3_k127_1215957_8 acetyltransferase - - - 0.000000000000006342 85.0
HFD3_k127_1215957_9 - - - - 0.0000001702 64.0
HFD3_k127_122077_0 - - - - 5.07e-296 951.0
HFD3_k127_122077_1 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008006 491.0
HFD3_k127_122077_10 COG0520 Selenocysteine lyase - - - 0.0000000000000000000000000000002621 140.0
HFD3_k127_122077_11 membrane transporter protein K07090 - - 0.000000000000000000000000000002189 130.0
HFD3_k127_122077_12 transmembrane signaling receptor activity - - - 0.00000000001028 74.0
HFD3_k127_122077_13 homoserine transmembrane transporter activity K03329,K16327 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - 0.00000000444 68.0
HFD3_k127_122077_14 - - - - 0.00009699 54.0
HFD3_k127_122077_2 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000001015 243.0
HFD3_k127_122077_3 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000001028 239.0
HFD3_k127_122077_4 Prephenate dehydratase K04518,K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000003051 229.0
HFD3_k127_122077_5 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000007524 201.0
HFD3_k127_122077_6 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000343 211.0
HFD3_k127_122077_7 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000003205 181.0
HFD3_k127_122077_8 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000003383 177.0
HFD3_k127_122077_9 PAS PAC domain-containing protein - - - 0.000000000000000000000000000000000000000000004509 182.0
HFD3_k127_1223768_0 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF K07402 - - 0.0000000000000000000000000000000000000000000000000001249 199.0
HFD3_k127_1232307_0 Helix-hairpin-helix domain K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 531.0
HFD3_k127_1232307_1 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007038 335.0
HFD3_k127_1232307_2 transcriptional K20342,K20391 - - 0.0000000000002351 83.0
HFD3_k127_1232307_3 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000007888 75.0
HFD3_k127_1234063_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 444.0
HFD3_k127_1234063_1 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 340.0
HFD3_k127_1234063_2 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007973 337.0
HFD3_k127_1234063_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001337 280.0
HFD3_k127_1234063_4 GCN5 family acetyltransferase - - - 0.00000002172 62.0
HFD3_k127_1248024_0 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000009755 211.0
HFD3_k127_1248024_1 - - - - 0.00000003788 63.0
HFD3_k127_12598_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 381.0
HFD3_k127_12598_1 Penicillin amidase K01434 - 3.5.1.11 0.00000000000000000000000000000000000000004502 170.0
HFD3_k127_12598_2 Biotin-requiring enzyme - - - 0.0000000001644 74.0
HFD3_k127_1291420_0 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000001179 203.0
HFD3_k127_1291420_1 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000002485 167.0
HFD3_k127_1291420_2 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000158 96.0
HFD3_k127_1291420_3 DUF218 domain - - - 0.00002606 52.0
HFD3_k127_1330651_0 Pyruvate phosphate dikinase, PEP K01006,K01007 - 2.7.9.1,2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000001134 273.0
HFD3_k127_1330651_1 Probable zinc-ribbon domain K03704 - - 0.000000000000000000000000000000000006029 140.0
HFD3_k127_1330651_2 type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis - - - 0.000000000222 69.0
HFD3_k127_1330651_3 flavin adenine dinucleotide binding - - - 0.00001433 52.0
HFD3_k127_1353170_0 chromosome segregation K03497 - - 0.00000000000000000000000000000000000000000000000000000000000001919 223.0
HFD3_k127_1353170_1 GAF domain - - - 0.0000000000000000000000000000000000000000000000000004281 203.0
HFD3_k127_1353170_2 PFAM response regulator receiver - - - 0.000000000000000000000000001104 117.0
HFD3_k127_1357823_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000765 595.0
HFD3_k127_1357823_1 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 546.0
HFD3_k127_1357823_10 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000003648 101.0
HFD3_k127_1357823_11 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 - 0.0000000000000000001994 104.0
HFD3_k127_1357823_12 amidohydrolase - - - 0.0002163 53.0
HFD3_k127_1357823_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 477.0
HFD3_k127_1357823_3 Arginase family K01476 GO:0003674,GO:0003824,GO:0004053,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 3.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006478 309.0
HFD3_k127_1357823_4 Natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 317.0
HFD3_k127_1357823_5 Acts as a magnesium transporter K03886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003449 274.0
HFD3_k127_1357823_6 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000002057 242.0
HFD3_k127_1357823_7 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000002461 153.0
HFD3_k127_1357823_8 response to abiotic stimulus - - - 0.000000000000000000000000000000000003774 145.0
HFD3_k127_1357823_9 Peptidase family S51 - - - 0.00000000000000000000000000000000235 147.0
HFD3_k127_1427404_0 CoA-binding protein K06929 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000001114 128.0
HFD3_k127_1427404_1 PFAM glycosyl transferase family 39 - - - 0.000000000000000000001882 101.0
HFD3_k127_1427404_2 LAGLIDADG-like domain - - - 0.00001468 56.0
HFD3_k127_145194_0 Elongation factor G, domain IV K02355 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005731 621.0
HFD3_k127_145194_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 504.0
HFD3_k127_145194_2 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 370.0
HFD3_k127_145194_3 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002879 272.0
HFD3_k127_145194_4 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885,K15977 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000466 242.0
HFD3_k127_145194_5 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000003608 132.0
HFD3_k127_145194_6 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000001353 124.0
HFD3_k127_145194_7 Protein of unknown function (DUF448) K07742 - - 0.0000000000000006303 87.0
HFD3_k127_145194_8 Flp/Fap pilin component K02651 - - 0.00007066 46.0
HFD3_k127_1477663_0 TIGRFAM Na Pi-cotransporter II-related protein K03324 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 375.0
HFD3_k127_1477663_1 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001704 265.0
HFD3_k127_1477663_2 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000001499 194.0
HFD3_k127_1477663_3 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.0000000000000000000000000000000000000000002434 174.0
HFD3_k127_1477663_4 Protein of unknown function (DUF3048) C-terminal domain - - - 0.000000000000000000000000000000000000003607 168.0
HFD3_k127_1477663_5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000000000000000000000007791 160.0
HFD3_k127_1477663_6 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.0000000000000000000007524 106.0
HFD3_k127_1477663_7 PFAM Prenyltransferase squalene oxidase - - - 0.000003499 59.0
HFD3_k127_1477663_8 Flavin containing amine oxidoreductase - - - 0.00003383 49.0
HFD3_k127_1490508_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 306.0
HFD3_k127_1490508_1 Putative 2OG-Fe(II) oxygenase - - - 0.0005571 52.0
HFD3_k127_1521953_0 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002982 259.0
HFD3_k127_1521953_1 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.0000000000000000000000000000000000000000000000000000000000514 217.0
HFD3_k127_1521953_2 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000001652 218.0
HFD3_k127_1521953_3 PFAM zinc finger, SWIM domain protein - - - 0.00000000000000000000021 99.0
HFD3_k127_1521953_4 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.00000000000003146 85.0
HFD3_k127_1521953_5 Nudix N-terminal - - - 0.0007204 44.0
HFD3_k127_1535897_0 acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 357.0
HFD3_k127_1535897_1 Thioesterase-like superfamily K07107 - - 0.00000000000000001155 91.0
HFD3_k127_1535897_2 integral membrane protein - - - 0.0000004459 59.0
HFD3_k127_1539643_0 Belongs to the aldehyde dehydrogenase family K22187 - - 0.000000000000000000000000000000000000000003119 158.0
HFD3_k127_1539643_1 YGGT family - - - 0.0000001337 59.0
HFD3_k127_1539643_2 Sortase family K07284 - 3.4.22.70 0.0001307 48.0
HFD3_k127_1542937_0 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 364.0
HFD3_k127_1542937_1 Predicted membrane protein (DUF2207) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001889 275.0
HFD3_k127_1542937_2 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K01992 - - 0.0000002273 58.0
HFD3_k127_1550542_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 569.0
HFD3_k127_1550542_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 381.0
HFD3_k127_1550542_2 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008693 385.0
HFD3_k127_1550542_3 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 334.0
HFD3_k127_1550542_4 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006526 307.0
HFD3_k127_1550542_5 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000123 248.0
HFD3_k127_1550542_6 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0040007,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.0000000000000000000000000000002869 127.0
HFD3_k127_1550542_7 - - - - 0.00000002671 64.0
HFD3_k127_1550542_8 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000004831 64.0
HFD3_k127_1554749_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.032e-261 825.0
HFD3_k127_1554749_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 483.0
HFD3_k127_1554749_10 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000008814 116.0
HFD3_k127_1554749_11 acetyltransferase - - - 0.000000000000000000001826 111.0
HFD3_k127_1554749_12 - - - - 0.0000000000003166 80.0
HFD3_k127_1554749_13 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.00001726 57.0
HFD3_k127_1554749_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 459.0
HFD3_k127_1554749_3 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 343.0
HFD3_k127_1554749_4 Riboflavin biosynthesis protein RibD K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005129 340.0
HFD3_k127_1554749_5 Belongs to the UPF0271 (lamB) family K07160 - - 0.00000000000000000000000000000000000000000000000000000000000000000004901 239.0
HFD3_k127_1554749_6 RNA polymerase sigma-54 factor K03092 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000007613 210.0
HFD3_k127_1554749_7 Riboflavin synthase K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.000000000000000000000000000000000000000000000000000000002982 205.0
HFD3_k127_1554749_8 Allophanate hydrolase subunit 2 K06350 - - 0.00000000000000000000000000000000000000000000002934 188.0
HFD3_k127_1554749_9 Allophanate hydrolase subunit 1 K06351 - - 0.0000000000000000000000000000000000000000003112 169.0
HFD3_k127_1566853_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 339.0
HFD3_k127_1580103_0 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 481.0
HFD3_k127_1580103_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0030312,GO:0032259,GO:0034641,GO:0035999,GO:0036211,GO:0040007,GO:0042084,GO:0042085,GO:0042558,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0050667,GO:0051186,GO:0071704,GO:0071944,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 383.0
HFD3_k127_1580103_2 Major facilitator superfamily K18215 - - 0.0000000000000000000000000000000000000000000000000000003006 209.0
HFD3_k127_1580103_3 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.00000000000000000000000000000000002921 138.0
HFD3_k127_1580103_4 Belongs to the DEAD box helicase family - GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 - 0.00000000000000000000000000000000003834 138.0
HFD3_k127_1580103_5 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.0000000000002135 74.0
HFD3_k127_1580103_6 Copper binding proteins, plastocyanin/azurin family - - - 0.000000000001349 81.0
HFD3_k127_1582348_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 477.0
HFD3_k127_1582348_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 494.0
HFD3_k127_1582348_10 Ribosomal L28 family K02902 - - 0.00000009556 58.0
HFD3_k127_1582348_11 metal-dependent membrane protease K07052 - - 0.0006031 53.0
HFD3_k127_1582348_2 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 297.0
HFD3_k127_1582348_3 Dak1_2 K07030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009558 287.0
HFD3_k127_1582348_4 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003733 260.0
HFD3_k127_1582348_5 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000009532 250.0
HFD3_k127_1582348_6 N2,N2-dimethylguanosine tRNA methyltransferase K08316 - 2.1.1.171 0.000000000000000000000000000001255 134.0
HFD3_k127_1582348_7 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.000000000000000000000000002128 119.0
HFD3_k127_1582348_8 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.00000000000000000001261 105.0
HFD3_k127_1582348_9 Uncharacterized ACR, COG1399 K07040 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000004156 94.0
HFD3_k127_1598662_0 Cell division protein FtsA K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 460.0
HFD3_k127_1598662_1 Subtilase family K08651 - 3.4.21.66 0.0000000000000000000000000000000000000000000001572 181.0
HFD3_k127_1598662_2 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000312 154.0
HFD3_k127_1610726_0 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007906 601.0
HFD3_k127_1610726_1 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000004313 143.0
HFD3_k127_1610726_2 cheY-homologous receiver domain - - - 0.00000000000000000002665 98.0
HFD3_k127_1611241_0 MMPL family K06994 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 553.0
HFD3_k127_1611241_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 366.0
HFD3_k127_1611241_10 binding. It is involved in the biological process described with metal ion transport K17686 GO:0000041,GO:0000139,GO:0000166,GO:0000302,GO:0000303,GO:0000305,GO:0000902,GO:0000904,GO:0001101,GO:0001501,GO:0001505,GO:0001568,GO:0001666,GO:0001701,GO:0001775,GO:0001836,GO:0001889,GO:0001942,GO:0001944,GO:0001974,GO:0002009,GO:0002082,GO:0002164,GO:0002252,GO:0002263,GO:0002285,GO:0002286,GO:0002287,GO:0002292,GO:0002293,GO:0002294,GO:0002366,GO:0002376,GO:0002520,GO:0002521,GO:0003674,GO:0003824,GO:0004008,GO:0005215,GO:0005375,GO:0005488,GO:0005507,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005768,GO:0005770,GO:0005773,GO:0005774,GO:0005783,GO:0005794,GO:0005798,GO:0005802,GO:0005829,GO:0005886,GO:0005887,GO:0005902,GO:0005903,GO:0005911,GO:0005923,GO:0006082,GO:0006139,GO:0006140,GO:0006163,GO:0006464,GO:0006520,GO:0006568,GO:0006570,GO:0006576,GO:0006584,GO:0006586,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006801,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0006873,GO:0006874,GO:0006875,GO:0006878,GO:0006882,GO:0006915,GO:0006950,GO:0006955,GO:0006979,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007589,GO:0007591,GO:0007593,GO:0007595,GO:0007610,GO:0007623,GO:0007626,GO:0008047,GO:0008144,GO:0008150,GO:0008152,GO:0008219,GO:0008270,GO:0008284,GO:0008324,GO:0008361,GO:0008544,GO:0008637,GO:0009058,GO:0009059,GO:0009072,GO:0009100,GO:0009101,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009308,GO:0009628,GO:0009636,GO:0009653,GO:0009712,GO:0009713,GO:0009719,GO:0009725,GO:0009790,GO:0009791,GO:0009792,GO:0009888,GO:0009893,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010039,GO:0010041,GO:0010042,GO:0010043,GO:0010155,GO:0010243,GO:0010273,GO:0010288,GO:0010468,GO:0010591,GO:0010592,GO:0010941,GO:0010959,GO:0012501,GO:0012505,GO:0012506,GO:0014070,GO:0014074,GO:0014910,GO:0014911,GO:0015075,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015677,GO:0015679,GO:0015680,GO:0016020,GO:0016021,GO:0016043,GO:0016323,GO:0016324,GO:0016358,GO:0016462,GO:0016530,GO:0016531,GO:0016532,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017016,GO:0017048,GO:0017076,GO:0017111,GO:0017144,GO:0018193,GO:0018205,GO:0018958,GO:0019219,GO:0019220,GO:0019222,GO:0019430,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019725,GO:0019752,GO:0019829,GO:0019899,GO:0021533,GO:0021549,GO:0021575,GO:0021587,GO:0021680,GO:0021692,GO:0021694,GO:0021695,GO:0021696,GO:0021697,GO:0021700,GO:0021702,GO:0021859,GO:0021860,GO:0021872,GO:0021879,GO:0021884,GO:0021953,GO:0021954,GO:0022008,GO:0022037,GO:0022404,GO:0022405,GO:0022607,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0022898,GO:0023052,GO:0030001,GO:0030003,GO:0030030,GO:0030054,GO:0030097,GO:0030098,GO:0030133,GO:0030135,GO:0030136,GO:0030139,GO:0030140,GO:0030141,GO:0030154,GO:0030182,GO:0030198,GO:0030199,GO:0030217,GO:0030234,GO:0030323,GO:0030324,GO:0030334,GO:0030335,GO:0030554,GO:0030659,GO:0030666,GO:0030670,GO:0030879,GO:0030900,GO:0030902,GO:0031069,GO:0031090,GO:0031175,GO:0031224,GO:0031226,GO:0031252,GO:0031253,GO:0031267,GO:0031323,GO:0031344,GO:0031346,GO:0031410,GO:0031526,GO:0031982,GO:0031984,GO:0032025,GO:0032409,GO:0032412,GO:0032501,GO:0032502,GO:0032535,GO:0032553,GO:0032555,GO:0032559,GO:0032588,GO:0032767,GO:0032879,GO:0032989,GO:0032990,GO:0033554,GO:0034220,GO:0034599,GO:0034614,GO:0034641,GO:0034645,GO:0034756,GO:0034757,GO:0034759,GO:0034760,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0035295,GO:0035434,GO:0035639,GO:0035710,GO:0036094,GO:0036119,GO:0036120,GO:0036211,GO:0036293,GO:0036294,GO:0036477,GO:0040012,GO:0040017,GO:0042093,GO:0042110,GO:0042127,GO:0042133,GO:0042221,GO:0042303,GO:0042325,GO:0042335,GO:0042414,GO:0042415,GO:0042417,GO:0042421,GO:0042423,GO:0042428,GO:0042430,GO:0042592,GO:0042623,GO:0042625,GO:0042626,GO:0042633,GO:0042981,GO:0042995,GO:0043005,GO:0043009,GO:0043025,GO:0043062,GO:0043066,GO:0043067,GO:0043069,GO:0043085,GO:0043086,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043200,GO:0043204,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043269,GO:0043271,GO:0043296,GO:0043367,GO:0043412,GO:0043434,GO:0043436,GO:0043467,GO:0043473,GO:0043492,GO:0043523,GO:0043524,GO:0043588,GO:0043682,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044092,GO:0044093,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044297,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0045121,GO:0045177,GO:0045321,GO:0045335,GO:0045793,GO:0046034,GO:0046189,GO:0046483,GO:0046631,GO:0046632,GO:0046649,GO:0046677,GO:0046683,GO:0046686,GO:0046688,GO:0046872,GO:0046873,GO:0046903,GO:0046907,GO:0046914,GO:0046915,GO:0046916,GO:0048066,GO:0048067,GO:0048085,GO:0048251,GO:0048286,GO:0048365,GO:0048468,GO:0048471,GO:0048511,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048583,GO:0048584,GO:0048646,GO:0048666,GO:0048667,GO:0048699,GO:0048729,GO:0048730,GO:0048731,GO:0048732,GO:0048771,GO:0048812,GO:0048813,GO:0048856,GO:0048858,GO:0048869,GO:0048878,GO:0050678,GO:0050679,GO:0050789,GO:0050790,GO:0050794,GO:0050801,GO:0050878,GO:0050896,GO:0051020,GO:0051049,GO:0051051,GO:0051087,GO:0051128,GO:0051130,GO:0051171,GO:0051174,GO:0051179,GO:0051208,GO:0051216,GO:0051234,GO:0051235,GO:0051270,GO:0051272,GO:0051341,GO:0051353,GO:0051541,GO:0051542,GO:0051591,GO:0051641,GO:0051649,GO:0051716,GO:0055065,GO:0055069,GO:0055070,GO:0055074,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0055086,GO:0060003,GO:0060255,GO:0060322,GO:0060429,GO:0060491,GO:0060541,GO:0060548,GO:0061008,GO:0061448,GO:0061687,GO:0062012,GO:0065007,GO:0065008,GO:0065009,GO:0070160,GO:0070482,GO:0070848,GO:0070887,GO:0071229,GO:0071230,GO:0071236,GO:0071241,GO:0071248,GO:0071276,GO:0071279,GO:0071280,GO:0071281,GO:0071284,GO:0071287,GO:0071310,GO:0071363,GO:0071417,GO:0071450,GO:0071451,GO:0071453,GO:0071456,GO:0071495,GO:0071704,GO:0071840,GO:0071944,GO:0072358,GO:0072359,GO:0072503,GO:0072507,GO:0072521,GO:0072593,GO:0080090,GO:0080134,GO:0085029,GO:0090066,GO:0090662,GO:0097159,GO:0097164,GO:0097190,GO:0097237,GO:0097367,GO:0097435,GO:0097458,GO:0097501,GO:0097708,GO:0098588,GO:0098589,GO:0098590,GO:0098655,GO:0098660,GO:0098662,GO:0098754,GO:0098771,GO:0098772,GO:0098773,GO:0098791,GO:0098805,GO:0098857,GO:0098858,GO:0098862,GO:0098869,GO:0099131,GO:0099132,GO:0099503,GO:0120025,GO:0120032,GO:0120034,GO:0120035,GO:0120036,GO:0120038,GO:0120039,GO:0140104,GO:1900542,GO:1901135,GO:1901137,GO:1901160,GO:1901214,GO:1901215,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901615,GO:1901617,GO:1901652,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902743,GO:1902745,GO:1903034,GO:1903036,GO:1903136,GO:1903578,GO:1904062,GO:1904063,GO:1904732,GO:1904752,GO:1904754,GO:1904959,GO:1990169,GO:1990637,GO:1990748,GO:2000145,GO:2000147 3.6.3.54 0.0006993 48.0
HFD3_k127_1611241_2 ATPase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 295.0
HFD3_k127_1611241_3 DoxX K16937 - 1.8.5.2 0.0000000000000000000000000000000000000000000000000000002249 202.0
HFD3_k127_1611241_4 transmembrane transport K01992 - - 0.000000000000000000000000000000008504 139.0
HFD3_k127_1611241_5 - - - - 0.0000000000000000000000000000006127 127.0
HFD3_k127_1611241_6 Acetyltransferase (GNAT) family - - - 0.000000000000000000005158 105.0
HFD3_k127_1611241_7 MFS/sugar transport protein - - - 0.00000000000003565 85.0
HFD3_k127_1611241_8 CsbD-like - - - 0.0000000001254 65.0
HFD3_k127_1611241_9 - - - - 0.0002372 48.0
HFD3_k127_1616344_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000007649 89.0
HFD3_k127_1631775_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 594.0
HFD3_k127_1631775_1 Kdo2-lipid A biosynthetic process K02517,K22311 - 2.3.1.241,2.3.1.265 0.000000000000000000000000000000000000000002562 173.0
HFD3_k127_1631775_2 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000002308 160.0
HFD3_k127_1631775_3 PHP domain protein - - - 0.0000000000000000000000000000000000004255 151.0
HFD3_k127_1631775_4 Glycosyl transferases group 1 K08256 GO:0000026,GO:0000030,GO:0000287,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0043167,GO:0043169,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046486,GO:0046488,GO:0046872,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.345 0.00000000000001214 79.0
HFD3_k127_1634576_0 COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K04108 - 1.3.7.9 1.193e-311 979.0
HFD3_k127_1634576_1 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000653 167.0
HFD3_k127_1634576_2 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.0000000000000000000008913 107.0
HFD3_k127_1640734_0 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000001458 139.0
HFD3_k127_1654219_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 454.0
HFD3_k127_1681248_0 COGs COG1132 ABC-type multidrug transport system ATPase and permease components K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 512.0
HFD3_k127_1681248_1 PFAM ABC transporter related K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 336.0
HFD3_k127_1681248_2 endonuclease III K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000003673 199.0
HFD3_k127_1681248_3 Beta-eliminating lyase K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000001004 162.0
HFD3_k127_1681248_4 Protein of unknown function DUF84 - - - 0.00000000000000000000000000000000001712 141.0
HFD3_k127_1681248_5 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.0000000000000000000000000000000003931 147.0
HFD3_k127_1681248_6 Multicopper - - - 0.0000000000000001246 85.0
HFD3_k127_1692566_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00124 - - 0.000000000000000000000000000000000000000000000000000000007836 213.0
HFD3_k127_1692566_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K14091 - 1.6.5.3 0.00000000000000000000000000008513 125.0
HFD3_k127_1692566_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.0000000000000000005584 87.0
HFD3_k127_1707717_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K03737 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 539.0
HFD3_k127_1707717_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009258 464.0
HFD3_k127_1707717_2 Cbs domain - - - 0.0000000000001568 81.0
HFD3_k127_1718075_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005058 368.0
HFD3_k127_1718075_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000005215 271.0
HFD3_k127_1718075_2 Protein of unknown function (DUF1290) - - - 0.0000000000000000000000000000000004027 133.0
HFD3_k127_1718075_3 Cell division protein FtsQ K03589 - - 0.0000000004056 73.0
HFD3_k127_1720727_0 - - - - 0.000000000000000000005608 104.0
HFD3_k127_1720727_1 PFAM AzlC family protein - - - 0.0000000000000000006644 100.0
HFD3_k127_1720727_2 - - - - 0.0000000000000007758 83.0
HFD3_k127_1720727_3 Phospholipid methyltransferase - - - 0.00000000000001511 83.0
HFD3_k127_1720727_4 Branched-chain amino acid transport protein (AzlD) - - - 0.000005741 58.0
HFD3_k127_1723894_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004908 571.0
HFD3_k127_1723894_1 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 310.0
HFD3_k127_1723894_2 PFAM band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 304.0
HFD3_k127_1723894_3 HELICc2 K03722 - 3.6.4.12 0.000000000000000000000000001125 121.0
HFD3_k127_1723894_4 positive regulation of growth rate K21687 GO:0003674,GO:0005488,GO:0008150,GO:0010035,GO:0010038,GO:0030955,GO:0031420,GO:0035864,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896 - 0.000000000000002719 80.0
HFD3_k127_1723894_5 PFAM alpha beta hydrolase fold - - - 0.00000000003292 73.0
HFD3_k127_1723894_6 PFAM ATP dependent DNA ligase K01971,K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000000109 61.0
HFD3_k127_1723894_7 F420H(2)-dependent quinone reductase - - - 0.0000003927 62.0
HFD3_k127_1749836_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008261 585.0
HFD3_k127_1749836_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000003877 166.0
HFD3_k127_1787697_0 N-terminal domain of (some) glycogen debranching enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 533.0
HFD3_k127_1787697_1 glycosyl transferase family 2 K21349 - 2.4.1.268 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 365.0
HFD3_k127_1787697_2 transferase activity, transferring glycosyl groups K21369 - 2.4.1.270 0.000000000000000000000000000000000000000000000000000000000004589 225.0
HFD3_k127_1787697_3 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000739 218.0
HFD3_k127_1789963_0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000008857 203.0
HFD3_k127_1789963_1 methyltransferase - - - 0.000000000000000000000000000002951 134.0
HFD3_k127_1789963_2 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.00000000000000000000000001873 110.0
HFD3_k127_1789963_3 protein histidine kinase activity K05962 - 2.7.13.1 0.00000000000000000000000201 112.0
HFD3_k127_1789963_4 Protein of unknown function (DUF3105) - - - 0.0000000000000000000004925 102.0
HFD3_k127_1789963_5 - - - - 0.00000000000000000003149 97.0
HFD3_k127_1799215_0 ATPases associated with a variety of cellular activities K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001613 274.0
HFD3_k127_1799215_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001689 262.0
HFD3_k127_1799215_2 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation K09811 - - 0.000000000000000000000000000000000002264 156.0
HFD3_k127_1799215_3 Peptidase M23 K21471 - - 0.00000000000000000000000000002214 134.0
HFD3_k127_1810117_0 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 299.0
HFD3_k127_1810117_1 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001097 269.0
HFD3_k127_1810117_2 Transmembrane secretion effector K08225 - - 0.0000000000000000000000000000000000000000000000000002793 195.0
HFD3_k127_1810117_3 NUDIX domain K03574 - 3.6.1.55 0.0000000000000007195 81.0
HFD3_k127_1812588_0 Tripartite tricarboxylate transporter TctA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007464 441.0
HFD3_k127_1812588_1 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000001062 208.0
HFD3_k127_1812588_2 Transcriptional regulator K05799 - - 0.000000000000000000000000000000003706 136.0
HFD3_k127_1830821_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 7.13e-213 675.0
HFD3_k127_1830821_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 576.0
HFD3_k127_1830821_2 DnaJ-class molecular chaperone with C-terminal Zn finger domain K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008769 279.0
HFD3_k127_1863068_0 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006826 283.0
HFD3_k127_1863068_1 Phosphotransferase enzyme family K02204 - 2.7.1.39 0.00000000000000000000000000000000002143 148.0
HFD3_k127_1863068_2 Sigma-54 interaction domain K03696 - - 0.000000000000000000000000000001862 122.0
HFD3_k127_1863068_3 Sigma-70 region 3 K02405 - - 0.0000000000000000000000000004763 123.0
HFD3_k127_1863068_4 response regulator - - - 0.000000000000000000000002546 121.0
HFD3_k127_1863068_5 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.0000001878 61.0
HFD3_k127_1863068_6 Gaf domain - - - 0.00003825 57.0
HFD3_k127_1863068_7 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 - 0.0001465 50.0
HFD3_k127_1877447_0 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 314.0
HFD3_k127_1877447_1 Two component transcriptional regulator, winged helix family K07669,K07672 GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009268,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010446,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0023052,GO:0030312,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0035556,GO:0043254,GO:0044087,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000001828 235.0
HFD3_k127_1877447_2 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000003997 211.0
HFD3_k127_1877447_3 Histidine kinase - - - 0.0000005292 59.0
HFD3_k127_1879279_0 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 3.743e-197 648.0
HFD3_k127_1879279_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000001051 72.0
HFD3_k127_1882101_0 heavy metal translocating P-type ATPase K01533 - 3.6.3.4 2.626e-213 687.0
HFD3_k127_1882101_1 - - - - 0.0000000000000000000008003 100.0
HFD3_k127_1887157_0 LysE type translocator - - - 0.000000000000000000000000000000000001287 145.0
HFD3_k127_1887157_1 Major Facilitator Superfamily - - - 0.00000000000000000000007499 112.0
HFD3_k127_1887157_2 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000001366 71.0
HFD3_k127_1887157_3 Endoribonuclease that initiates mRNA decay K18682 - - 0.0002967 48.0
HFD3_k127_190126_0 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 492.0
HFD3_k127_190126_1 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 356.0
HFD3_k127_190126_10 Belongs to the universal stress protein A family - - - 0.00000000000000352 85.0
HFD3_k127_190126_11 Prokaryotic dksA/traR C4-type zinc finger - - - 0.0000000000002909 70.0
HFD3_k127_190126_12 Member of the two-component regulatory system devR devS (dosR dosS) involved in onset of the dormancy response. When phosphorylated binds the promoter of at least its own and Acr (hspX) gene in response to hypoxia. Activates its own transcription under hypoxic but not aerobic conditions, probably binds as a dimer to tandem binding sites within the devR and hspX promoters. Accepts a phosphate group from devS (dosS) and from dosT - - - 0.00003266 51.0
HFD3_k127_190126_13 Lysin motif - - - 0.00069 52.0
HFD3_k127_190126_2 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007178 283.0
HFD3_k127_190126_3 DoxX K16937 - 1.8.5.2 0.0000000000000000000000000000000000000000000000000000000002849 208.0
HFD3_k127_190126_4 response regulator - - - 0.0000000000000000000000000000000000000000000000000004794 188.0
HFD3_k127_190126_5 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000001868 198.0
HFD3_k127_190126_6 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000000000000000000000000000000000000000001339 172.0
HFD3_k127_190126_7 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000003965 137.0
HFD3_k127_190126_8 von Willebrand factor, type A K07114 - - 0.000000000000000000000002171 106.0
HFD3_k127_190126_9 Universal stress protein - - - 0.0000000000000001303 90.0
HFD3_k127_1915913_0 Type ii secretion system protein e K02283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 505.0
HFD3_k127_1915913_1 Type II secretion system (T2SS), protein F K12510 - - 0.000000000000000000000000000000000000000000003669 178.0
HFD3_k127_1915913_2 AAA domain K02282 - - 0.00000000000000000000000000000000000000000004322 176.0
HFD3_k127_1915913_3 von Willebrand factor type A domain K07114 - - 0.000000000000000002362 98.0
HFD3_k127_1915913_4 Flp pilus assembly protein CpaB K02279 - - 0.0000000001596 70.0
HFD3_k127_1915913_5 TadE-like protein - - - 0.0000000002994 67.0
HFD3_k127_1915913_6 response regulator - - - 0.000000002477 67.0
HFD3_k127_1915913_7 cheY-homologous receiver domain - - - 0.00000000627 65.0
HFD3_k127_1934960_0 Dehydrogenase E1 component K00615 - 2.2.1.1 4.28e-262 830.0
HFD3_k127_1934960_1 HAD-hyrolase-like - - - 0.0000000000000000000000000000000000000002973 153.0
HFD3_k127_1934960_2 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000001895 153.0
HFD3_k127_1934960_3 - - - - 0.00000000003459 75.0
HFD3_k127_1940332_0 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000004657 244.0
HFD3_k127_1940332_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01751,K01754,K17989 - 4.3.1.15,4.3.1.17,4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000408 231.0
HFD3_k127_1940332_2 Peptidase family M23 - - - 0.000000000000000000001252 109.0
HFD3_k127_1940332_3 Multicopper oxidase K00368 - 1.7.2.1 0.00000000000000001503 83.0
HFD3_k127_1940332_4 Diguanylate cyclase - - - 0.000000000001521 77.0
HFD3_k127_1944005_0 R3H domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 595.0
HFD3_k127_1944005_1 Methyltransferase small domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000004012 256.0
HFD3_k127_1944005_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000001174 205.0
HFD3_k127_1944005_3 - - - - 0.00000000000000000000000000000000000005598 157.0
HFD3_k127_1944005_4 Cyclic-di-AMP receptor - - - 0.00000000000000000000000000000000006365 136.0
HFD3_k127_1944005_5 AAA ATPase domain - - - 0.0000000002404 72.0
HFD3_k127_1950778_0 protein tyrosine kinase activity K03593 - - 0.0000000000000000000000000000000000000000002482 171.0
HFD3_k127_1950778_1 Proto-chlorophyllide reductase 57 kD subunit - - - 0.0000000000000000000000000000000002012 139.0
HFD3_k127_1952746_0 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 521.0
HFD3_k127_1952746_1 Polysaccharide biosynthesis protein K01711,K15856 - 1.1.1.281,4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 405.0
HFD3_k127_1952746_2 Double zinc ribbon - - - 0.0000000000000000000000000000000002116 138.0
HFD3_k127_1952746_3 Activator of Hsp90 ATPase - - - 0.00000000000000000002083 96.0
HFD3_k127_1952746_4 Belongs to the UPF0758 family K03630 - - 0.00000000000004677 75.0
HFD3_k127_1952746_5 alpha-ribazole phosphatase activity K02226,K07814 - 3.1.3.73 0.0000000005923 67.0
HFD3_k127_1954808_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 454.0
HFD3_k127_1954808_1 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000001406 218.0
HFD3_k127_1954808_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000127 179.0
HFD3_k127_1954808_3 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000003321 136.0
HFD3_k127_1954808_4 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000006027 116.0
HFD3_k127_1954808_5 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000003979 75.0
HFD3_k127_1954808_6 ribosomal protein L30 K02907 - - 0.000000007223 59.0
HFD3_k127_1956057_0 Beta-eliminating lyase K01667 - 4.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 589.0
HFD3_k127_1956057_1 Berberine and berberine like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 538.0
HFD3_k127_1956057_2 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003795 259.0
HFD3_k127_1956057_3 CAAX protease self-immunity - - - 0.00000000000000000000000000000000000000000000000000000002636 207.0
HFD3_k127_1956057_4 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000001361 171.0
HFD3_k127_1956057_5 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000001397 150.0
HFD3_k127_1956057_6 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000002125 128.0
HFD3_k127_1956057_7 F420H(2)-dependent quinone reductase - - - 0.000000000000000000000000000008137 125.0
HFD3_k127_1956057_8 PFAM Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000143 79.0
HFD3_k127_1993112_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 609.0
HFD3_k127_1993112_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000249 227.0
HFD3_k127_1993112_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000001672 183.0
HFD3_k127_1993112_3 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000002823 86.0
HFD3_k127_1993112_4 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000001303 85.0
HFD3_k127_1993112_5 Baseplate J-like protein K01218 - 3.2.1.78 0.000006502 59.0
HFD3_k127_1994017_0 PFAM TPR repeat-containing protein - - - 0.0000000000000000000000000000000005909 143.0
HFD3_k127_1994017_1 MgtE intracellular N domain - - - 0.0000000000000000000022 99.0
HFD3_k127_1995195_0 Belongs to the RimK family K05827,K05844,K14940,K18310 - 6.3.1.17,6.3.2.32,6.3.2.41,6.3.2.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003802 300.0
HFD3_k127_1995195_1 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.000000000000000000000000000000000000004816 153.0
HFD3_k127_1995195_2 lysine biosynthesis protein LysW K05826 - - 0.000000000000001539 78.0
HFD3_k127_1999870_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000001648 214.0
HFD3_k127_1999870_1 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000005839 82.0
HFD3_k127_2010041_0 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000001112 136.0
HFD3_k127_2011056_0 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000003283 207.0
HFD3_k127_2011056_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000009166 184.0
HFD3_k127_2011056_2 protein serine/threonine phosphatase activity - - - 0.00005243 57.0
HFD3_k127_2030394_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 319.0
HFD3_k127_2030394_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000302 287.0
HFD3_k127_2030394_2 DegV family - - - 0.000000000000000000000000004589 116.0
HFD3_k127_2030394_3 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000001205 60.0
HFD3_k127_2037120_0 Domain of unknown function (DUF1998) K06877 - - 6.512e-280 882.0
HFD3_k127_2037120_1 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 306.0
HFD3_k127_2037120_2 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000001979 218.0
HFD3_k127_2037120_3 Winged helix DNA-binding domain K09927 - - 0.0000000000000000000000000000000000000000000000000002821 203.0
HFD3_k127_2037120_4 Exonuclease K07502 - - 0.0000000000000000000000000000000000000000001789 179.0
HFD3_k127_2037120_5 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.0000000000000000000000000000000003577 139.0
HFD3_k127_2037120_6 GCN5 family acetyltransferase - - - 0.00000000000000000000000000002185 130.0
HFD3_k127_2037120_7 With GsiABD is involved in the transport of glutathione into the cell K02033 - - 0.00000000000000007214 91.0
HFD3_k127_2041177_0 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000311 434.0
HFD3_k127_2041177_1 Cysteine-rich domain K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 374.0
HFD3_k127_2041177_2 Transporter associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 302.0
HFD3_k127_2041177_3 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.000000000000000000000000000000000000000000000000005315 188.0
HFD3_k127_2041177_4 PFAM FAD linked oxidase domain protein K11472 - - 0.000000000000000000000000000000000000000000358 173.0
HFD3_k127_2041177_5 EVE domain - - - 0.0000000000000000000000000000004673 134.0
HFD3_k127_2044792_0 ornithine cyclodeaminase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 372.0
HFD3_k127_2044792_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 286.0
HFD3_k127_2044792_2 Protein of unknown function DUF58 - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006249 287.0
HFD3_k127_2044792_3 von Willebrand factor (vWF) type A domain K07114,K12511 - - 0.00000000000000000000000000000000000000000000000000000003857 215.0
HFD3_k127_2044792_4 von Willebrand factor (vWF) type A domain K07114 - - 0.00000000000000000000000000000000000000000000000001783 202.0
HFD3_k127_2044792_5 cheY-homologous receiver domain K11443 - - 0.0000000000000000006484 95.0
HFD3_k127_2044792_7 signal transduction histidine kinase K07642 - 2.7.13.3 0.00000008844 64.0
HFD3_k127_2068599_0 PFAM glycosyl transferase family 3 K00756 - 2.4.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 446.0
HFD3_k127_2068599_1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006058 312.0
HFD3_k127_2068599_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000003236 169.0
HFD3_k127_2093518_0 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 428.0
HFD3_k127_2093518_1 PFAM Cytochrome c oxidase caa3-type, assembly factor CtaG-related - - - 0.00000000000000000000000000000000003464 145.0
HFD3_k127_2093518_2 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0040007,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 0.000000000000000000002643 96.0
HFD3_k127_2093903_0 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001309 288.0
HFD3_k127_2093903_1 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000549 230.0
HFD3_k127_2093903_2 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000000007544 190.0
HFD3_k127_2093903_3 MOSC domain containing protein K07140 - - 0.0000000000000000000000000000000000000000052 168.0
HFD3_k127_2093903_4 Belongs to the acetyltransferase family. ArgA subfamily K03830 - - 0.0000000000000000000000000000003637 133.0
HFD3_k127_2130420_0 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 427.0
HFD3_k127_2130420_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 298.0
HFD3_k127_2139128_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 6.2.1.1 1.076e-317 983.0
HFD3_k127_2139128_1 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 374.0
HFD3_k127_2139128_2 May be involved in recombinational repair of damaged DNA K03631 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000001593 146.0
HFD3_k127_2139128_3 regulation of translation K03530 - - 0.000000000000000000000000000006302 121.0
HFD3_k127_2139128_4 DinB family - - - 0.0001195 53.0
HFD3_k127_2182797_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005407 344.0
HFD3_k127_2182797_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005916 254.0
HFD3_k127_2182797_2 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000004817 99.0
HFD3_k127_2182797_3 - - - - 0.000000000000000001086 88.0
HFD3_k127_2182797_4 - - - - 0.0000000000003655 72.0
HFD3_k127_2186740_0 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 409.0
HFD3_k127_2186740_1 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000000000000003699 201.0
HFD3_k127_2186740_2 - - - - 0.0003507 45.0
HFD3_k127_2200875_0 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 2.497e-233 731.0
HFD3_k127_2200875_1 Catalyzes the transfer of the amino group of L-glutamate to LysW -aminoadipate 6-semialdehyde, generating LysW -gamma-L- lysine K05830 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 431.0
HFD3_k127_2200875_10 membrane - - - 0.0000000000000000000000000000000000000000000941 174.0
HFD3_k127_2200875_2 Catalyzes the NADPH-dependent reduction of LysW - aminoadipate 6-phosphate to yield LysW -aminoadipate 6- semialdehyde K05829 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008529 406.0
HFD3_k127_2200875_3 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 376.0
HFD3_k127_2200875_4 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 315.0
HFD3_k127_2200875_5 Catalyzes the release of L-lysine from LysW -gamma-L- lysine K05831 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006212 306.0
HFD3_k127_2200875_6 Aldehyde dehydrogenase family K00128 - 1.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009051 308.0
HFD3_k127_2200875_7 Belongs to the acetylglutamate kinase family. LysZ subfamily K05828 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003108 247.0
HFD3_k127_2200875_8 PFAM ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp K05827 - 6.3.2.43 0.00000000000000000000000000000000000000000000000000000001328 199.0
HFD3_k127_2200875_9 CHASE2 K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000008797 185.0
HFD3_k127_226698_0 PFAM UBA THIF-type NAD FAD binding protein K21029,K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007472 493.0
HFD3_k127_226698_1 Amidohydrolase family - - - 0.00000000000000000000003797 115.0
HFD3_k127_2300147_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004327 281.0
HFD3_k127_2300147_1 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001133 282.0
HFD3_k127_2300147_2 NhaP-type Na H and K H K03316 - - 0.000000000000000000000000000000000000000000000000000000000000000002629 242.0
HFD3_k127_2300147_3 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000000000000000000000000000000000000001526 194.0
HFD3_k127_2300147_4 phosphorelay signal transduction system - - - 0.000000000000003857 81.0
HFD3_k127_2300147_5 Predicted integral membrane protein (DUF2269) - - - 0.0000000001029 67.0
HFD3_k127_2300147_6 OST-HTH/LOTUS domain - - - 0.0004039 53.0
HFD3_k127_2332339_0 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000005721 224.0
HFD3_k127_2332339_1 cheY-homologous receiver domain - - - 0.00000000000000000042 96.0
HFD3_k127_2332339_2 phosphonoacetaldehyde hydrolase activity K07025 - - 0.00000000000009831 74.0
HFD3_k127_2335689_0 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00000000000000000000000000000000000000000003952 166.0
HFD3_k127_2335689_1 SMART Peptidoglycan-binding LysM - - - 0.0000000000000000000000009236 114.0
HFD3_k127_2335689_2 (GGDEF) domain - - - 0.00000000000102 81.0
HFD3_k127_2345470_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000001162 241.0
HFD3_k127_2345470_1 Flotillin K07192 - - 0.000000000000000000000000000000000000000000000000000000000000000000002714 262.0
HFD3_k127_2345470_2 nucleotide catabolic process K11751 - 3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000000000000000000000007141 242.0
HFD3_k127_2345470_3 Inositol monophosphatase K01092 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043167,GO:0043169,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 0.000000000000000000000000000000000000000000000000001094 204.0
HFD3_k127_2345470_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.000000000000000000000000000000000000000000000000001139 190.0
HFD3_k127_2345470_5 - - - - 0.00000000000007636 78.0
HFD3_k127_2350523_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006705 404.0
HFD3_k127_2350523_1 exonuclease of the beta-lactamase fold involved in RNA K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 379.0
HFD3_k127_2350523_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001549 304.0
HFD3_k127_2350523_3 dihydrofolate reductase activity K00287,K18589 - 1.5.1.3 0.00000000000000000000000000000000000000000000000000000001861 202.0
HFD3_k127_2350523_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000003555 176.0
HFD3_k127_2350523_5 FecR protein - - - 0.00007395 55.0
HFD3_k127_2350523_6 DinB superfamily - - - 0.0001062 51.0
HFD3_k127_2350523_7 acetoin utilization protein K04768 - - 0.0005579 50.0
HFD3_k127_2362632_0 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000004081 209.0
HFD3_k127_2362632_1 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000124 110.0
HFD3_k127_2365269_0 ATPase associated with various cellular K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 427.0
HFD3_k127_2365269_1 Belongs to the SEDS family K03588 GO:0002682,GO:0002684,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 309.0
HFD3_k127_2365269_2 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006485 295.0
HFD3_k127_2365269_3 Cell division protein FtsI penicillin-binding protein K05364 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002809 272.0
HFD3_k127_2365269_4 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000002217 224.0
HFD3_k127_2365269_5 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000005314 194.0
HFD3_k127_2365269_6 YbaK prolyl-tRNA synthetase associated region - - - 0.00000000000000000000000000000000002661 139.0
HFD3_k127_2365726_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K01848 - 5.4.99.2 1.065e-214 682.0
HFD3_k127_2365726_1 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005788 308.0
HFD3_k127_2365726_2 TIGRFAM methylmalonyl-CoA mutase C-terminal domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000009071 192.0
HFD3_k127_2365726_3 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 - 0.0000000000000000000000000000000000000000000000001045 179.0
HFD3_k127_2365726_4 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000001383 158.0
HFD3_k127_2365726_5 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000001512 61.0
HFD3_k127_2378564_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 2.666e-206 653.0
HFD3_k127_2378564_1 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000144 88.0
HFD3_k127_2378564_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000004199 79.0
HFD3_k127_2378564_3 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000002221 66.0
HFD3_k127_2396054_0 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003283 257.0
HFD3_k127_2396054_1 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000004552 236.0
HFD3_k127_2396054_2 Periplasmic binding protein-like domain K02529 - - 0.000000000000000000000000000000000000000009483 161.0
HFD3_k127_2408986_0 beta' subunit K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 364.0
HFD3_k127_2408986_1 COGs COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 340.0
HFD3_k127_2408986_2 - - - - 0.0000000000000000000000000000000000000000000000000000002732 205.0
HFD3_k127_2408986_3 pyridoxamine 5-phosphate - - - 0.000000000000000000000000000000000000000000000106 172.0
HFD3_k127_2408986_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K00982,K03564 - 1.11.1.15,2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000002142 163.0
HFD3_k127_2408986_5 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000003587 168.0
HFD3_k127_2408986_6 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000001069 139.0
HFD3_k127_2408986_7 ATPase associated with various cellular K03924 - - 0.00000000000000000000000000002857 124.0
HFD3_k127_2408986_8 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.000000000000000000114 93.0
HFD3_k127_2408986_9 phospholipase Carboxylesterase K07011,K18286 - 3.5.4.40 0.00000005847 62.0
HFD3_k127_2443883_0 Conserved repeat domain - - - 0.00000000000001849 77.0
HFD3_k127_2443883_1 O-Antigen ligase - - - 0.000000003584 70.0
HFD3_k127_2443883_2 Tetratricopeptide TPR_2 repeat protein - - - 0.000001582 61.0
HFD3_k127_2449534_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 602.0
HFD3_k127_2449534_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008862 275.0
HFD3_k127_2449534_2 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000003569 190.0
HFD3_k127_2449534_3 PucR C-terminal helix-turn-helix domain - - - 0.000004292 59.0
HFD3_k127_2449534_4 Cupin domain - - - 0.00006695 54.0
HFD3_k127_2449534_5 PFAM GGDEF domain containing protein - - - 0.0008529 50.0
HFD3_k127_2461958_0 Belongs to the class-I aminoacyl-tRNA synthetase family K15526 - 6.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007512 356.0
HFD3_k127_2461958_1 aminopeptidase activity - - - 0.000000000000000000000000003556 125.0
HFD3_k127_247297_0 Transmembrane secretion effector - - - 0.000000000000000000000000000000001723 145.0
HFD3_k127_247297_1 Bacterial protein of unknown function (DUF951) - - - 0.000000000000000000000005495 108.0
HFD3_k127_247297_2 Bacterial protein of unknown function (DUF881) - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000003364 81.0
HFD3_k127_2474703_0 Drug exporters of the RND superfamily K06994 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 505.0
HFD3_k127_2474703_1 PFAM EamA-like transporter family - - - 0.00000000000000000000000000000000000000001581 156.0
HFD3_k127_2480206_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.494e-249 777.0
HFD3_k127_2499262_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 539.0
HFD3_k127_2499262_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 411.0
HFD3_k127_2499262_2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000007894 266.0
HFD3_k127_2499262_3 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000002271 224.0
HFD3_k127_2499262_4 permease - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000000000000000000000000004444 155.0
HFD3_k127_2499262_5 Abc transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000001485 138.0
HFD3_k127_2499262_6 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000001333 138.0
HFD3_k127_2499262_7 Uncharacterised protein, DegV family COG1307 - - - 0.000000000000009833 81.0
HFD3_k127_250797_0 Amidohydrolase family K06015 - 3.5.1.81 2.806e-209 674.0
HFD3_k127_250797_1 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 451.0
HFD3_k127_250797_2 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009156,GO:0009161,GO:0009163,GO:0009164,GO:0009165,GO:0009167,GO:0009168,GO:0009987,GO:0015949,GO:0015950,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0032261,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0043173,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 334.0
HFD3_k127_250797_3 Glycolate oxidase K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008443 321.0
HFD3_k127_250797_4 AAA domain - - - 0.000000000000000001006 93.0
HFD3_k127_250797_5 - - - - 0.0001486 54.0
HFD3_k127_250819_0 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008454 305.0
HFD3_k127_250819_1 Efflux ABC transporter permease protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 300.0
HFD3_k127_250819_10 Psort location CytoplasmicMembrane, score 10.00 - - - 0.00000000000000000003853 104.0
HFD3_k127_250819_2 thymidine kinase K00857 - 2.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000001269 258.0
HFD3_k127_250819_3 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000005254 217.0
HFD3_k127_250819_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000001312 135.0
HFD3_k127_250819_6 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.000000000000000000000000000004404 139.0
HFD3_k127_250819_7 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000009909 117.0
HFD3_k127_250819_8 Binds the 23S rRNA K02909 - - 0.000000000000000000000000002349 113.0
HFD3_k127_250819_9 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000003853 104.0
HFD3_k127_2513068_0 Protein conserved in bacteria - - - 6.738e-206 651.0
HFD3_k127_2513068_1 Berberine and berberine like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 557.0
HFD3_k127_2513068_2 cyclic nucleotide binding K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001183 258.0
HFD3_k127_2513068_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000002022 218.0
HFD3_k127_2513068_4 Alpha/beta hydrolase family - - - 0.0001591 47.0
HFD3_k127_2513536_0 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003957 325.0
HFD3_k127_2513536_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.00000000000000000000000000000000004559 136.0
HFD3_k127_2513536_2 Helix-turn-helix domain - - - 0.000000000000000000000001328 111.0
HFD3_k127_2513536_3 MFS_1 like family - - - 0.000000000000006013 88.0
HFD3_k127_2513536_4 PFAM IS1 transposase K07480 - - 0.0000007159 52.0
HFD3_k127_2516944_0 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 3.373e-220 718.0
HFD3_k127_2516944_1 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 382.0
HFD3_k127_2516944_2 Metal-sensitive transcriptional repressor K21600 - - 0.0000000000000000003189 102.0
HFD3_k127_2516944_3 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0040007,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 0.000000000000000003556 88.0
HFD3_k127_2540068_0 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 483.0
HFD3_k127_2540068_1 PFAM Phenylalanine and histidine ammonia-lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 453.0
HFD3_k127_2540068_2 PFAM response regulator receiver K02483,K07658,K07668 - - 0.000000000000000000000000000000000000000000000000000003182 200.0
HFD3_k127_2540068_3 Bacterial transferase hexapeptide (six repeats) K02617 GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008270,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043168,GO:0043169,GO:0043199,GO:0046872,GO:0046914,GO:0050897,GO:0071890,GO:1901681 - 0.00000000000000000000000000000000000000000003785 169.0
HFD3_k127_2540068_4 PFAM Haloacid dehalogenase domain protein hydrolase K07025 - - 0.00000000000000000000000000000001255 133.0
HFD3_k127_2572262_0 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 417.0
HFD3_k127_2572262_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01652,K12673 - 2.2.1.6,2.5.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 342.0
HFD3_k127_2572262_2 Glycine D-amino acid oxidase (deaminating) K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008925 291.0
HFD3_k127_2572262_3 ABC transporter permease K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003381 283.0
HFD3_k127_2572262_4 amidase activity K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000001004 244.0
HFD3_k127_2572262_5 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000002194 209.0
HFD3_k127_2572262_6 TIGRFAM acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.000000000000000000000000000000008074 142.0
HFD3_k127_2572262_7 PFAM pyridoxamine 5'-phosphate oxidase-related - - - 0.000000000000000000000000000005513 137.0
HFD3_k127_2572262_8 regulatory protein GntR HTH - - - 0.000000000000000000000000004576 116.0
HFD3_k127_2579844_0 SERine Proteinase INhibitors K13963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004909 301.0
HFD3_k127_2579844_1 Peptidase family M13 K07386 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002016 262.0
HFD3_k127_2607826_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 379.0
HFD3_k127_2607826_1 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008092 315.0
HFD3_k127_2607826_10 COGs COG1733 transcriptional regulator protein - - - 0.00000000000000000000000002297 112.0
HFD3_k127_2607826_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000002761 113.0
HFD3_k127_2607826_12 SnoaL-like domain - - - 0.000000004088 63.0
HFD3_k127_2607826_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 314.0
HFD3_k127_2607826_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000002899 213.0
HFD3_k127_2607826_4 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000207 164.0
HFD3_k127_2607826_5 Lysin motif - - - 0.000000000000000000000000000000000001564 153.0
HFD3_k127_2607826_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000006967 134.0
HFD3_k127_2607826_7 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000001126 139.0
HFD3_k127_2607826_8 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 - 0.0000000000000000000000000000001947 127.0
HFD3_k127_2607826_9 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000001046 120.0
HFD3_k127_2666948_0 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 322.0
HFD3_k127_2666948_1 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 316.0
HFD3_k127_2666948_2 - - - - 0.000000000001802 79.0
HFD3_k127_2675426_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 311.0
HFD3_k127_2675426_1 SMART Nucleotide binding protein, PINc - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006571 282.0
HFD3_k127_2675426_2 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000001276 188.0
HFD3_k127_2675426_3 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000003743 136.0
HFD3_k127_2698147_0 PFAM Type II IV secretion system protein K02283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006232 370.0
HFD3_k127_2698147_1 Major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000023 226.0
HFD3_k127_2698147_2 type II secretion K12511 - - 0.0005956 51.0
HFD3_k127_2698147_3 bacterial-type flagellum organization - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.0008318 51.0
HFD3_k127_2698492_0 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006126 320.0
HFD3_k127_2698492_1 Prokaryotic glutathione synthetase, ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000008608 205.0
HFD3_k127_2698492_2 Aminoacyl-tRNA editing domain K19055 - - 0.000000000000000000000000000000000003817 141.0
HFD3_k127_2700143_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006981 462.0
HFD3_k127_2700143_1 DNA polymerase Ligase (LigD) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001716 248.0
HFD3_k127_2700143_10 PFAM Chromate transporter K07240 - - 0.000000000000009541 81.0
HFD3_k127_2700143_11 - - - - 0.000000000003337 76.0
HFD3_k127_2700143_12 negative regulation of growth - - - 0.00000001038 62.0
HFD3_k127_2700143_2 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000004894 248.0
HFD3_k127_2700143_3 Radical SAM superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000003426 237.0
HFD3_k127_2700143_4 Trypsin-like peptidase domain - - - 0.0000000000000000000000000000000000000000000000000000000002176 213.0
HFD3_k127_2700143_5 DNA ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000002194 203.0
HFD3_k127_2700143_6 PFAM diacylglycerol kinase catalytic region - - - 0.000000000000000000000000000000000000000198 161.0
HFD3_k127_2700143_7 Small integral membrane protein - - - 0.00000000000000000000000000000001876 134.0
HFD3_k127_2700143_8 cheY-homologous receiver domain - - - 0.00000000000000000002238 97.0
HFD3_k127_2700143_9 chromate transport K07240 - - 0.000000000000003142 87.0
HFD3_k127_2750874_0 NTF2-like N-terminal transpeptidase domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 355.0
HFD3_k127_2750874_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000745 296.0
HFD3_k127_277653_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.000000000000000000000000000000000000000000000000000000000001744 215.0
HFD3_k127_277653_1 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000629 184.0
HFD3_k127_277653_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000006108 168.0
HFD3_k127_277653_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000001248 110.0
HFD3_k127_2791132_0 Type ii secretion system protein e K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 394.0
HFD3_k127_2791132_1 PFAM type II secretion system protein K12510 - - 0.000000000000000000000000000000000000000000000000000000000000000000006019 245.0
HFD3_k127_2791132_2 Type II secretion system (T2SS), protein F K12511 - - 0.000000000000000000000000000000000000000000000000000003288 201.0
HFD3_k127_2791132_3 GTP binding - - - 0.000000000000000000000000000000000000000000000003358 194.0
HFD3_k127_2791132_4 competence protein - - - 0.00000000000000000000000000000000001019 143.0
HFD3_k127_2791132_5 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000005395 109.0
HFD3_k127_2791132_6 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000003263 115.0
HFD3_k127_2791132_7 YceI-like domain - - - 0.00000000000000004951 84.0
HFD3_k127_2862093_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006959 473.0
HFD3_k127_2862093_1 TIGRFAM gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000003117 168.0
HFD3_k127_2862093_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000003765 155.0
HFD3_k127_2904204_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 2.7e-251 788.0
HFD3_k127_2904204_1 Involved in the biosynthesis of porphyrin-containing compound - GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000002016 234.0
HFD3_k127_2904204_2 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000144 193.0
HFD3_k127_2955226_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009748 467.0
HFD3_k127_2955226_1 PFAM Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000003011 142.0
HFD3_k127_2955226_2 Modulates RecA activity K03565 - - 0.00000000000000000000001375 108.0
HFD3_k127_3016194_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 7.807e-311 975.0
HFD3_k127_3016194_1 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 346.0
HFD3_k127_3016194_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001894 274.0
HFD3_k127_3016194_3 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000004735 198.0
HFD3_k127_3016194_4 Competence protein ComEA K02237 - - 0.0000000000000000000000000353 115.0
HFD3_k127_3016194_5 - - - - 0.00000005642 63.0
HFD3_k127_3016194_6 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.0000008391 57.0
HFD3_k127_3018870_0 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 310.0
HFD3_k127_3018870_1 Binding-protein-dependent transport system inner membrane component K05773 - - 0.000000000000000000000000000000000000000000000000000000000000004622 231.0
HFD3_k127_3018870_2 TOBE domain K02010,K06857 - 3.6.3.30,3.6.3.55 0.00000000000000000000000000000000000000000000000000000002383 218.0
HFD3_k127_3018870_3 Maf-like protein K06287 - - 0.000000000000000000000000000001013 131.0
HFD3_k127_3018870_4 ATPase activity K02010,K02049,K02068,K02071,K06857,K10112 - 3.6.3.30,3.6.3.55 0.000001356 51.0
HFD3_k127_3021187_0 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 325.0
HFD3_k127_3021187_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004108 251.0
HFD3_k127_3021187_2 PFAM amidohydrolase - - - 0.000000000000000000000000000000006085 138.0
HFD3_k127_3021187_3 luxR family - - - 0.000000003662 60.0
HFD3_k127_3022618_0 PFAM Amidohydrolase 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009915 401.0
HFD3_k127_3022618_1 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006045 337.0
HFD3_k127_3022618_2 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000004458 207.0
HFD3_k127_3022618_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000002071 189.0
HFD3_k127_3024253_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007311 577.0
HFD3_k127_3024253_1 Aminotransferase K00812,K10907 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 475.0
HFD3_k127_3024253_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 350.0
HFD3_k127_3024253_3 Glyoxalase-like domain - - - 0.0000000000000000000000000001747 119.0
HFD3_k127_3024253_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.3.5.6,6.3.5.7 0.0000000000000002883 87.0
HFD3_k127_3024253_5 Diacylglycerol kinase K00887,K00901 - 2.7.1.107,2.7.1.66 0.000000000000009145 76.0
HFD3_k127_3024253_6 Ribbon-helix-helix protein, copG family - - - 0.0000000000005498 69.0
HFD3_k127_3047879_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 567.0
HFD3_k127_3047879_1 amidohydrolase K21613 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001445 261.0
HFD3_k127_3047879_2 peptidase dimerisation domain protein K01436 - - 0.00000000000000000000000000000000000000000000000000000000000003188 229.0
HFD3_k127_3047879_3 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000037 192.0
HFD3_k127_3047879_4 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000001512 181.0
HFD3_k127_3061847_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 345.0
HFD3_k127_3061847_1 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 310.0
HFD3_k127_3061847_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000288 300.0
HFD3_k127_3061847_3 Transcriptional regulatory protein, C terminal K02483,K07669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001127 267.0
HFD3_k127_3061847_4 CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002969 269.0
HFD3_k127_3061847_5 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000957 198.0
HFD3_k127_3061847_6 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.00000000000000000000000000000001987 139.0
HFD3_k127_3061847_7 Cytochrome c - - - 0.0000000000001631 79.0
HFD3_k127_3067663_0 carbohydrate transport K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 430.0
HFD3_k127_3067663_1 Metal-independent alpha-mannosidase (GH125) K09704 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006662 394.0
HFD3_k127_3067663_2 PFAM ABC transporter related K10112 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015169,GO:0015399,GO:0015405,GO:0015430,GO:0015605,GO:0015711,GO:0015748,GO:0015794,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0098656,GO:1901264,GO:1901505 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 385.0
HFD3_k127_3067663_3 transmembrane transport K02025,K15771,K17312 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 298.0
HFD3_k127_3067663_4 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009895 289.0
HFD3_k127_3067663_5 PFAM Methyltransferase type 12 - - - 0.00000000000000000000000000000000000000000002514 174.0
HFD3_k127_3067663_6 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000003049 156.0
HFD3_k127_3067663_7 Peptidase family M28 K19701 - 3.4.11.10,3.4.11.6 0.000002842 56.0
HFD3_k127_3071353_0 PFAM glycosyl transferase, family 51 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 424.0
HFD3_k127_3071353_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000003815 117.0
HFD3_k127_3071353_2 NUDIX domain K03574 - 3.6.1.55 0.0000000000001297 78.0
HFD3_k127_3095286_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 6.038e-235 752.0
HFD3_k127_3119211_0 PFAM PSP1 domain protein - - - 0.0000000000000000000000000000000000000000000000000000002276 208.0
HFD3_k127_3119211_1 Belongs to the FPP GGPP synthase family K00805 - 2.5.1.30 0.000000000000000000000000000000000000000000000000000002513 203.0
HFD3_k127_3163627_0 Belongs to the RtcB family K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 555.0
HFD3_k127_3163627_1 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007607 443.0
HFD3_k127_3163627_10 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000007286 133.0
HFD3_k127_3163627_11 PFAM Archease protein family (DUF101 UPF0211) - - - 0.000000000000000000000000005956 115.0
HFD3_k127_3163627_12 AMP binding - - - 0.000000000000000000001063 107.0
HFD3_k127_3163627_13 PFAM Major Facilitator Superfamily - - - 0.0000000000000000002269 101.0
HFD3_k127_3163627_14 Peptidoglycan-binding domain 1 protein - - - 0.000000000000001637 85.0
HFD3_k127_3163627_15 hyperosmotic response K04065 - - 0.0000000000000351 79.0
HFD3_k127_3163627_16 Methyltransferase type 11 K07755 - 2.1.1.137 0.0000000003144 63.0
HFD3_k127_3163627_17 Domain of unknown function (DU1801) - - - 0.0000000007263 66.0
HFD3_k127_3163627_18 Putative zinc-finger - - - 0.00000001309 63.0
HFD3_k127_3163627_2 Arginyl tRNA synthetase N terminal dom K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 427.0
HFD3_k127_3163627_3 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 409.0
HFD3_k127_3163627_4 COG3911 Predicted ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003515 264.0
HFD3_k127_3163627_5 PFAM peptidase S1 and S6, chymotrypsin Hap K08070 - 1.3.1.74 0.0000000000000000000000000000000000000000000000000000000000000000001281 245.0
HFD3_k127_3163627_6 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000007136 227.0
HFD3_k127_3163627_7 Belongs to the carbohydrate kinase PfkB family. LacC subfamily K00882 - 2.7.1.56 0.00000000000000000000000000000000000000000000000000000000001212 218.0
HFD3_k127_3163627_8 Methyltransferase type 11 K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000002251 186.0
HFD3_k127_3163627_9 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000003248 136.0
HFD3_k127_3167600_0 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003728 263.0
HFD3_k127_3167600_1 PFAM conserved K07027 - - 0.00000000000000000000000000000000000000000000000000000000003347 220.0
HFD3_k127_3167600_2 PHP-associated - - - 0.000000000000000000000000000000000000000000002716 172.0
HFD3_k127_3167600_3 Belongs to the glycosyltransferase 26 family K05946 - 2.4.1.187 0.0000000000000000000000463 100.0
HFD3_k127_3167600_4 phosphatidylinositol metabolic process K13671 - - 0.00000002334 66.0
HFD3_k127_3167600_5 Glycosyltransferase family 87 - - - 0.000002661 61.0
HFD3_k127_3175789_0 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000000000000000000000000000000000000000000000000004105 202.0
HFD3_k127_3175789_1 PFAM ATP-binding region, ATPase domain protein K07636 - 2.7.13.3 0.00000001556 68.0
HFD3_k127_3183579_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 543.0
HFD3_k127_3183579_1 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006779 498.0
HFD3_k127_3183579_2 Putative FMN-binding domain K07734 - - 0.00000000000000000000000000000000000000000000000000000000000000000004703 237.0
HFD3_k127_3183579_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K03737 - 1.2.7.1 0.000000000000000000000000000000000000000000001743 167.0
HFD3_k127_3183579_4 Integral membrane protein TerC family - - - 0.00000000000000000000000000000000000000004723 159.0
HFD3_k127_3183579_5 homoserine transmembrane transporter activity - - - 0.0000000000000000000000000000000000000005738 163.0
HFD3_k127_3183579_7 - - - - 0.00002804 56.0
HFD3_k127_3183579_8 Helix-turn-helix domain - - - 0.0001298 51.0
HFD3_k127_3212685_0 Belongs to the binding-protein-dependent transport system permease family K01997,K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 342.0
HFD3_k127_3212685_1 Iron permease FTR1 family K07243 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 296.0
HFD3_k127_3214853_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 1.307e-257 818.0
HFD3_k127_3214853_1 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 3.021e-239 749.0
HFD3_k127_3214853_10 ferric iron binding K02380 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008199,GO:0009061,GO:0009987,GO:0010467,GO:0015980,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0046914,GO:0051604,GO:0055114,GO:0071704,GO:1901564 - 0.000000000000000000000000000000000000000001125 172.0
HFD3_k127_3214853_11 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000001464 150.0
HFD3_k127_3214853_12 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000001148 83.0
HFD3_k127_3214853_13 - - - - 0.0000000000000001475 89.0
HFD3_k127_3214853_14 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000003198 89.0
HFD3_k127_3214853_2 formate dehydrogenase, beta subunit K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 381.0
HFD3_k127_3214853_3 GTP cyclohydrolase I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000408 291.0
HFD3_k127_3214853_4 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000002816 251.0
HFD3_k127_3214853_5 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004092 247.0
HFD3_k127_3214853_6 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000002898 232.0
HFD3_k127_3214853_7 Metallo-beta-lactamase superfamily K13075 - 3.1.1.81 0.0000000000000000000000000000000000000000000000001071 188.0
HFD3_k127_3214853_8 nitrite reductase [NAD(P)H] activity - - - 0.0000000000000000000000000000000000000000000000002345 188.0
HFD3_k127_3214853_9 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000002447 174.0
HFD3_k127_329081_0 Sodium:sulfate symporter transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000001221 242.0
HFD3_k127_329081_1 Bacterial regulatory proteins, tetR family - - - 0.00000008056 55.0
HFD3_k127_3311822_0 introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX K03404,K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000877 484.0
HFD3_k127_3311822_1 Amidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009051 418.0
HFD3_k127_3311822_2 F420-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000004703 166.0
HFD3_k127_3311822_3 type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis - - - 0.000000000000000000000000000000000000000008795 165.0
HFD3_k127_3318365_0 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 477.0
HFD3_k127_3318365_1 Adenylate K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 396.0
HFD3_k127_3318365_2 Protein of unknown function (DUF2891) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 359.0
HFD3_k127_3318365_3 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000001868 195.0
HFD3_k127_3318365_4 HTTM domain protein - - - 0.000000000000000000000000000000000000000002526 173.0
HFD3_k127_3318365_5 - - - - 0.00000000000004882 80.0
HFD3_k127_3330551_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 352.0
HFD3_k127_3330551_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009766 327.0
HFD3_k127_3330551_3 zinc ion binding K04477,K07053 - 3.1.3.97 0.0000004221 62.0
HFD3_k127_3335364_0 AMP-binding enzyme C-terminal domain K08295 - 6.2.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 565.0
HFD3_k127_3335364_1 Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000652 333.0
HFD3_k127_3335364_2 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009351 254.0
HFD3_k127_3335364_3 Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000003327 138.0
HFD3_k127_3335364_4 Pfam:DUF385 - - - 0.0000000000000000000000001535 121.0
HFD3_k127_3343433_0 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 333.0
HFD3_k127_3343433_1 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000007825 177.0
HFD3_k127_3343433_2 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000002899 160.0
HFD3_k127_3343433_3 ATP synthesis coupled electron transport K05568 - - 0.0000000000000233 87.0
HFD3_k127_3343433_4 - - - - 0.0000000618 63.0
HFD3_k127_3343829_0 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 323.0
HFD3_k127_3343829_1 PFAM peptidase M48 Ste24p K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 311.0
HFD3_k127_3343829_2 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001257 248.0
HFD3_k127_3343829_3 Ndr family - - - 0.0000000000000000000000000000000000000000000000002711 185.0
HFD3_k127_3343829_4 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000000000003017 187.0
HFD3_k127_3343829_5 efflux transmembrane transporter activity K02004,K16918 - - 0.000000000000000000000000000000000000000001728 173.0
HFD3_k127_3343829_6 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000002216 134.0
HFD3_k127_3343829_7 RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000001974 124.0
HFD3_k127_3343829_8 AraC-like ligand binding domain - - - 0.00000000000000001736 89.0
HFD3_k127_3343829_9 AntiSigma factor - - - 0.000000000000006716 87.0
HFD3_k127_3347033_0 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009966 312.0
HFD3_k127_3347033_1 His Kinase A (phosphoacceptor) domain K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000001485 220.0
HFD3_k127_3347033_2 AAA domain K02282 - - 0.0000000000000000000000000000000000000000000000002396 194.0
HFD3_k127_3347033_3 cheY-homologous receiver domain - - - 0.0000000000000000000001364 102.0
HFD3_k127_3375469_0 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009042 274.0
HFD3_k127_3375469_1 CO dehydrogenase flavoprotein C-terminal domain K11178 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000003433 259.0
HFD3_k127_3375469_2 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain K03520,K11177 - 1.17.1.4,1.2.5.3 0.0000000000000000000000000000000000000000000000000001316 191.0
HFD3_k127_3375469_3 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000002344 186.0
HFD3_k127_3375469_4 PFAM ABC transporter related K01990,K16907 - - 0.00000000000000000000000000000000000000000004874 161.0
HFD3_k127_3375469_5 activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation - - - 0.00000000000107 75.0
HFD3_k127_3375469_6 acetyltransferase - - - 0.00000000003263 74.0
HFD3_k127_3375469_7 Belongs to the acetyltransferase family. ArgA subfamily - - - 0.00000001836 67.0
HFD3_k127_3386311_0 TIGRFAM stage V sporulation protein E, cell division protein FtsW K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009848 310.0
HFD3_k127_3386311_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008141 303.0
HFD3_k127_3386311_2 Mur ligase family, catalytic domain K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 298.0
HFD3_k127_3386311_3 Cell wall formation K00075 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000003402 256.0
HFD3_k127_3386311_4 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000285 235.0
HFD3_k127_3386311_5 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000007722 113.0
HFD3_k127_3408932_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006453 377.0
HFD3_k127_3408932_1 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000114 234.0
HFD3_k127_3408932_2 methylated-DNA-[protein]-cysteine S-methyltransferase activity K00567,K07443,K07452 - 2.1.1.63 0.00000000000000000006829 94.0
HFD3_k127_3408932_3 - - - - 0.00000182 59.0
HFD3_k127_3433272_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 329.0
HFD3_k127_3433272_1 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000001601 195.0
HFD3_k127_3443080_0 Belongs to the malate synthase family K01638 - 2.3.3.9 1.631e-233 733.0
HFD3_k127_3443080_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 342.0
HFD3_k127_3443080_2 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001006 234.0
HFD3_k127_3454810_0 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000003154 225.0
HFD3_k127_3454810_1 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000111 162.0
HFD3_k127_3454810_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000002994 162.0
HFD3_k127_3454810_3 PFAM Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.00000000000000000000000000000000000001842 145.0
HFD3_k127_3454810_4 Probable molybdopterin binding domain K07141 - 2.7.7.76 0.000000000000000000000000000008555 126.0
HFD3_k127_3454810_5 Prokaryotic cytochrome b561 - - - 0.00000001208 66.0
HFD3_k127_3454810_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00005102 52.0
HFD3_k127_3462713_0 LUD domain - - - 1.626e-224 719.0
HFD3_k127_3462713_1 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000004294 204.0
HFD3_k127_3462713_2 Cysteine-rich domain K11473 - - 0.00000000001838 64.0
HFD3_k127_3462713_3 Cysteine-rich secretory protein family - - - 0.00000000009536 62.0
HFD3_k127_3466918_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000629 399.0
HFD3_k127_3466918_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 317.0
HFD3_k127_3466918_2 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 293.0
HFD3_k127_3466918_3 Conserved hypothetical protein 698 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004041 268.0
HFD3_k127_3466918_4 F420H(2)-dependent quinone reductase - - - 0.000000000000000000000000021 113.0
HFD3_k127_3466918_5 response regulator K07684,K07693 - - 0.00000000000000256 85.0
HFD3_k127_3466918_6 thiolester hydrolase activity K06889 - - 0.000009092 59.0
HFD3_k127_346801_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 4.279e-213 680.0
HFD3_k127_346801_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001011 270.0
HFD3_k127_346801_2 carboxymethylenebutenolidase activity K01061,K07100 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000002729 240.0
HFD3_k127_346801_3 HemN C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002025 239.0
HFD3_k127_346801_4 phosphoribosyltransferase K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000412 220.0
HFD3_k127_346801_5 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000002657 156.0
HFD3_k127_346801_6 Universal stress protein - - - 0.00000000000000000000005296 105.0
HFD3_k127_346801_7 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000001468 60.0
HFD3_k127_3483175_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1303.0
HFD3_k127_3483175_1 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002392 280.0
HFD3_k127_3483175_2 phenazine biosynthesis protein PhzF family K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000371 205.0
HFD3_k127_3483175_3 lactoylglutathione lyase activity - - - 0.000000000000000000000000000001431 132.0
HFD3_k127_3483175_4 Major facilitator Superfamily - - - 0.00000000000000000003868 103.0
HFD3_k127_3483986_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 2.032e-202 653.0
HFD3_k127_3483986_1 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 424.0
HFD3_k127_3483986_2 Nucleotidyl transferase K00971 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 302.0
HFD3_k127_3483986_3 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000001594 237.0
HFD3_k127_3483986_4 Methicillin resistance protein K05363,K11693 - 2.3.2.10,2.3.2.16 0.0000000000000000000000000000000000000000000002521 182.0
HFD3_k127_3483986_5 PFAM Methicillin resistance protein - - - 0.000000000000000000000000000000000003605 154.0
HFD3_k127_3483986_6 Serine aminopeptidase, S33 K07018 - - 0.00000000000000000009196 104.0
HFD3_k127_3483986_7 Periplasmic copper-binding protein (NosD) - - - 0.0000000000003561 82.0
HFD3_k127_3506586_0 Belongs to the peptidase S8 family - - - 1.117e-263 850.0
HFD3_k127_3506586_1 Peptidase M1 membrane alanine aminopeptidase K01256,K08776 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 604.0
HFD3_k127_3506586_10 - - - - 0.0001065 53.0
HFD3_k127_3506586_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006839 470.0
HFD3_k127_3506586_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 359.0
HFD3_k127_3506586_4 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006982 303.0
HFD3_k127_3506586_5 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000004214 220.0
HFD3_k127_3506586_6 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000000000000000000000000000003407 201.0
HFD3_k127_3506586_7 - - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000003002 190.0
HFD3_k127_3506586_8 ABC transporter K06020 - 3.6.3.25 0.000000000000000000000000000000000000000000000000002124 186.0
HFD3_k127_3506586_9 Rdx family K07401 - - 0.000000000000000000000004776 106.0
HFD3_k127_3527908_0 Cell division protein FtsA K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 428.0
HFD3_k127_3527908_1 Iron permease FTR1 family K07243 - - 0.000000000000000000000000000000000000000000001921 175.0
HFD3_k127_3527908_2 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000001289 169.0
HFD3_k127_3527908_3 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000004319 137.0
HFD3_k127_3527908_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000002557 130.0
HFD3_k127_3527908_5 NUDIX domain - - - 0.000000000000000001596 91.0
HFD3_k127_3527908_6 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid K05946 - 2.4.1.187 0.000000000000094 74.0
HFD3_k127_3527908_7 DinB family - - - 0.000000000002641 75.0
HFD3_k127_3527908_8 Lactonase, 7-bladed beta-propeller - - - 0.00000000005068 74.0
HFD3_k127_3540150_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 7.762e-209 664.0
HFD3_k127_3540150_1 DHH family K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007181 404.0
HFD3_k127_3540150_10 Periplasmic component of the Tol biopolymer transport system - - - 0.00000000000283 78.0
HFD3_k127_3540150_11 mttA/Hcf106 family K03116,K03117 - - 0.0000004448 58.0
HFD3_k127_3540150_12 polysaccharide deacetylase - - - 0.00002182 57.0
HFD3_k127_3540150_2 Peptidase family M41 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003976 400.0
HFD3_k127_3540150_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 332.0
HFD3_k127_3540150_4 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 297.0
HFD3_k127_3540150_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004768 248.0
HFD3_k127_3540150_6 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591,K13421 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10,4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000002409 242.0
HFD3_k127_3540150_7 ABC transporter (Permease) K02042 - - 0.00000000000000000000000000000000000000000000008565 194.0
HFD3_k127_3540150_8 organic phosphonate transport K02044 - - 0.0000000000000000000000000000000000000000467 173.0
HFD3_k127_3540150_9 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.000000000000000000005106 106.0
HFD3_k127_3544278_0 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 405.0
HFD3_k127_3544278_1 Protein of unknown function (DUF983) - - - 0.000000000000000007377 93.0
HFD3_k127_3566946_0 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 536.0
HFD3_k127_3566946_1 Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000001007 209.0
HFD3_k127_3566946_2 Electron transfer flavoprotein K03522 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 - 0.00000000000000000000000000009352 127.0
HFD3_k127_3569671_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 609.0
HFD3_k127_3569671_1 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000002333 135.0
HFD3_k127_357647_0 glycyl-tRNA aminoacylation K01880 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 531.0
HFD3_k127_357647_1 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000007423 248.0
HFD3_k127_357647_2 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000003585 186.0
HFD3_k127_357647_3 Bacterial PH domain - - - 0.0000007266 57.0
HFD3_k127_3578591_0 Prolyl oligopeptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 391.0
HFD3_k127_3578591_1 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000005387 179.0
HFD3_k127_3592328_0 Serine threonine protein kinase involved in cell cycle control K07178 - 2.7.11.1 0.0000000000000000000000000000000000000008659 157.0
HFD3_k127_3592328_1 ParB-like nuclease domain K03497 - - 0.0000000000003546 75.0
HFD3_k127_3592328_2 - - - - 0.000000000000693 77.0
HFD3_k127_3617061_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 512.0
HFD3_k127_3617061_1 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005084 276.0
HFD3_k127_3617061_2 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.0000000000000000000000000000000000000000005226 164.0
HFD3_k127_3617061_3 NUDIX domain K03574 - 3.6.1.55 0.000000000000000002184 91.0
HFD3_k127_3626890_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 306.0
HFD3_k127_3626890_1 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000001787 229.0
HFD3_k127_3626890_2 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000001841 221.0
HFD3_k127_3626890_3 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000001018 169.0
HFD3_k127_3626890_4 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000004645 139.0
HFD3_k127_3626890_5 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000001244 118.0
HFD3_k127_3626890_6 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000002064 58.0
HFD3_k127_3664098_0 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033,K15581 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 347.0
HFD3_k127_3664098_1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005928 289.0
HFD3_k127_3664098_2 ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002609 281.0
HFD3_k127_3664098_3 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000656 278.0
HFD3_k127_3664098_4 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 0.000000000000000000000000000000000000000000000000239 202.0
HFD3_k127_3664098_5 amidase activity K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000002406 161.0
HFD3_k127_3664098_6 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000002878 149.0
HFD3_k127_3753827_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001224 291.0
HFD3_k127_3753827_1 GyrI-like small molecule binding domain K15770 - - 0.0000000000000000000000000000000000000002153 158.0
HFD3_k127_3753827_2 regulation of RNA biosynthetic process - - - 0.000000000000000000005786 99.0
HFD3_k127_3753827_3 Exporter of polyketide K01992 - - 0.0000000624 65.0
HFD3_k127_3763242_0 Glycosyl hydrolases family 15 - - - 1.388e-234 741.0
HFD3_k127_3763242_1 Putative cyclase K07130 - 3.5.1.9 0.000000000000000000000000000000000000000000000000000002349 200.0
HFD3_k127_3763242_2 KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000000000000000000000001365 144.0
HFD3_k127_3763242_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00006705 56.0
HFD3_k127_3767795_0 Predicted Permease Membrane Region - - - 2.007e-247 775.0
HFD3_k127_3767795_1 Aminotransferase class I and II K09758 - 4.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000001035 253.0
HFD3_k127_3777885_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 299.0
HFD3_k127_3777885_1 Mate efflux family protein - - - 0.00000000000000000000000000000000000000000000000000001232 206.0
HFD3_k127_3777885_2 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.00000000000000000000000000000000000000000000000007276 183.0
HFD3_k127_3781257_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 341.0
HFD3_k127_3781257_1 PFAM FAD dependent oxidoreductase K00303 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 321.0
HFD3_k127_3781257_2 D-aminopeptidase K16203 - - 0.000000000000000000000000000000000000000000000000000000000000009789 226.0
HFD3_k127_3781257_3 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.000000000000000000000004708 104.0
HFD3_k127_3781257_4 Preprotein translocase SecG subunit K03075 - - 0.000000001482 61.0
HFD3_k127_379281_0 PFAM transferase hexapeptide repeat containing protein K16881 - 2.7.7.13,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 593.0
HFD3_k127_379281_1 Lrp/AsnC ligand binding domain - - - 0.00000000000000000000000504 108.0
HFD3_k127_3821825_0 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000003368 252.0
HFD3_k127_3821825_1 ECF sigma factor K03088 - - 0.000000000000000000000000000000005078 142.0
HFD3_k127_3821825_2 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.00000000000000000000000000001321 125.0
HFD3_k127_3821825_3 ABC-type transport system involved in cytochrome c biogenesis permease component K02194 - - 0.00000000000000006725 89.0
HFD3_k127_3821825_4 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000008915 79.0
HFD3_k127_3821825_5 response regulator receiver - - - 0.00000000001806 72.0
HFD3_k127_3821825_6 COG2010 Cytochrome c, mono- and diheme variants - - - 0.000000001707 64.0
HFD3_k127_3821825_7 Tfp pilus assembly protein FimV - - - 0.00002895 55.0
HFD3_k127_3843563_0 Amidohydrolase family K01464,K01465,K01466 - 3.5.2.2,3.5.2.3,3.5.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 537.0
HFD3_k127_3843563_1 Aconitase family (aconitate hydratase) K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009601 356.0
HFD3_k127_3843563_2 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000003289 238.0
HFD3_k127_387771_0 COG2513 PEP phosphonomutase and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 308.0
HFD3_k127_387771_1 Aconitase family (aconitate hydratase) K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000001913 187.0
HFD3_k127_387771_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000008615 178.0
HFD3_k127_387771_3 PFAM Major Facilitator Superfamily - - - 0.00000000000008432 80.0
HFD3_k127_3887514_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000483 211.0
HFD3_k127_3887514_1 Histidine biosynthesis bifunctional protein hisIE K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000001366 184.0
HFD3_k127_3887514_2 PFAM Haloacid dehalogenase domain protein hydrolase K07025,K20862 - 3.1.3.102,3.1.3.104 0.000000000000000000000000000000000000000002689 175.0
HFD3_k127_3887514_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000001365 111.0
HFD3_k127_3887514_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000002203 61.0
HFD3_k127_3902202_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 2.858e-227 729.0
HFD3_k127_3902202_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 326.0
HFD3_k127_3902202_10 - - - - 0.00001494 50.0
HFD3_k127_3902202_2 Provides the (R)-glutamate required for cell wall biosynthesis K01776,K02428 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 3.6.1.66,5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000007526 231.0
HFD3_k127_3902202_3 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K00760,K04075 - 2.4.2.8,6.3.4.19 0.0000000000000000000000000000000000000000000000000004554 202.0
HFD3_k127_3902202_4 PFAM PfkB domain protein - - - 0.0000000000000000000000000000000000001108 158.0
HFD3_k127_3902202_5 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.00000000000000000000000000000000001088 146.0
HFD3_k127_3902202_6 PFAM response regulator receiver K02282 - - 0.00000000000000000000000000000001838 140.0
HFD3_k127_3902202_7 Bacterial periplasmic substrate-binding proteins K02030 - - 0.000000000000000000002314 105.0
HFD3_k127_3902202_8 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000002428 100.0
HFD3_k127_3902202_9 SMART HNH nuclease - - - 0.000000001446 66.0
HFD3_k127_392056_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004314 366.0
HFD3_k127_392056_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007554 322.0
HFD3_k127_392056_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000002404 263.0
HFD3_k127_392056_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002342 251.0
HFD3_k127_392056_4 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000002192 229.0
HFD3_k127_392056_5 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000000003827 172.0
HFD3_k127_392056_6 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000001143 154.0
HFD3_k127_392056_7 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000001777 145.0
HFD3_k127_392056_8 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000003405 123.0
HFD3_k127_392056_9 acetyltransferase - - - 0.000000001791 68.0
HFD3_k127_3927329_0 Belongs to the TPP enzyme family K00158,K01652,K21428 GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016744,GO:0016999,GO:0017000,GO:0017144,GO:0019842,GO:0030976,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0048037,GO:0050662,GO:0097159,GO:1901363,GO:1901681 1.2.3.3,2.2.1.12,2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 633.0
HFD3_k127_3927329_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004455,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 447.0
HFD3_k127_3927329_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0000000000000000000000000000001162 128.0
HFD3_k127_3927329_3 Psort location Cytoplasmic, score K09684 - - 0.0000000000000002468 88.0
HFD3_k127_3929328_0 TIGRFAM Na H antiporter, bacterial form K03316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 358.0
HFD3_k127_3929328_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 338.0
HFD3_k127_3929328_2 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.000000000000000000000000000000000000000000003023 170.0
HFD3_k127_3929328_3 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000000000003332 144.0
HFD3_k127_3929328_4 Universal bacterial protein YeaZ K14742 - - 0.000000000000001609 85.0
HFD3_k127_3947215_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 1.979e-208 659.0
HFD3_k127_3947215_1 - - - - 0.000000000000002133 84.0
HFD3_k127_3947215_2 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.00001449 54.0
HFD3_k127_3976084_0 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.00000000000000000000000001349 115.0
HFD3_k127_3976084_1 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000004404 121.0
HFD3_k127_3976084_2 ACT domain protein - - - 0.0001007 50.0
HFD3_k127_4004467_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00003,K00058,K01752,K16843 - 1.1.1.3,1.1.1.310,1.1.1.399,1.1.1.95,4.3.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 466.0
HFD3_k127_4004467_1 ATPase with chaperone activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006065 388.0
HFD3_k127_4004467_2 Aminotransferase class-V K00436 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 332.0
HFD3_k127_4004467_3 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000001079 235.0
HFD3_k127_4004467_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000004646 219.0
HFD3_k127_4004467_5 Zincin-like metallopeptidase - - - 0.000000000000000000000000000001186 124.0
HFD3_k127_4004467_6 NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.000000000000000002264 91.0
HFD3_k127_4004467_7 - - - - 0.000000000003105 79.0
HFD3_k127_4017760_0 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 363.0
HFD3_k127_4017760_1 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000002224 194.0
HFD3_k127_4017760_2 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000005548 167.0
HFD3_k127_4017760_3 PFAM PfkB domain protein K00856 - 2.7.1.20 0.0000000000000000000000000000000000006088 142.0
HFD3_k127_4017760_4 - - - - 0.000000000000000000000000009599 120.0
HFD3_k127_4021495_0 protein kinase activity K06915 - - 1.033e-197 631.0
HFD3_k127_4021495_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 593.0
HFD3_k127_4021495_2 3-isopropylmalate dehydrogenase activity K00030 - 1.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 490.0
HFD3_k127_4021495_3 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 387.0
HFD3_k127_4021495_4 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000201 165.0
HFD3_k127_4021495_5 translation initiation inhibitor, yjgF family - - - 0.00000000000000000000000002666 119.0
HFD3_k127_4021495_6 - - - - 0.0000000003637 73.0
HFD3_k127_4028534_0 Sigma-54 interaction domain K03696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007334 392.0
HFD3_k127_4028534_1 Adenylate K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 392.0
HFD3_k127_4029793_0 belongs to the aldehyde dehydrogenase family K00135,K08324 GO:0001505,GO:0003674,GO:0003824,GO:0004777,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008150,GO:0008152,GO:0009013,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009448,GO:0009450,GO:0009987,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0032787,GO:0034641,GO:0042133,GO:0042135,GO:0042402,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:0072329,GO:0097164,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.2.1.16,1.2.1.20,1.2.1.24,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 596.0
HFD3_k127_4029793_1 PFAM NADH ubiquinone oxidoreductase, 20 K00331,K14088 - 1.6.5.3 0.0000000000000000000000000000000000000000000000003003 184.0
HFD3_k127_4029793_2 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.0000000000000009893 78.0
HFD3_k127_4045111_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 1.341e-234 747.0
HFD3_k127_4045111_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 604.0
HFD3_k127_4045111_10 methyltransferase - - - 0.00000000000000000000000000000000005522 149.0
HFD3_k127_4045111_11 Belongs to the CinA family K03742 - 3.5.1.42 0.000000000000000000000000000001149 126.0
HFD3_k127_4045111_12 Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides K03478 - 3.5.1.105 0.000000000000000000000000005564 129.0
HFD3_k127_4045111_13 Methyltransferase domain K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000005176 116.0
HFD3_k127_4045111_14 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000009633 109.0
HFD3_k127_4045111_15 SMART helix-turn-helix domain protein - - - 0.0000000000000000007676 99.0
HFD3_k127_4045111_17 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000009515 75.0
HFD3_k127_4045111_2 Sugar (and other) transporter K08369 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 483.0
HFD3_k127_4045111_3 DNA segregation ATPase FtsK SpoIIIE K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005113 471.0
HFD3_k127_4045111_4 PFAM aspartate glutamate uridylate kinase K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 405.0
HFD3_k127_4045111_5 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 389.0
HFD3_k127_4045111_6 Homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000002496 241.0
HFD3_k127_4045111_7 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000004329 228.0
HFD3_k127_4045111_8 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000008536 229.0
HFD3_k127_4045111_9 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000007555 180.0
HFD3_k127_4050242_0 Anticodon-binding domain of tRNA K01870 - 6.1.1.5 8.761e-313 996.0
HFD3_k127_4050242_1 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000000000004623 213.0
HFD3_k127_4050242_2 Ribbon-helix-helix domain - - - 0.000000000000000000000000000000000000000000003787 173.0
HFD3_k127_4050242_3 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000002388 129.0
HFD3_k127_4050242_4 ATP-binding region ATPase domain protein K07683 - 2.7.13.3 0.000000001006 71.0
HFD3_k127_4059063_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 356.0
HFD3_k127_4059063_1 Papain-like cysteine protease AvrRpt2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 353.0
HFD3_k127_4059063_2 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004408 246.0
HFD3_k127_4059063_3 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000009729 249.0
HFD3_k127_4059063_4 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.0000008384 62.0
HFD3_k127_4083078_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 438.0
HFD3_k127_4083078_1 Molybdopterin oxidoreductase, Fe4S4 K00336,K05299 - 1.17.1.10,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 448.0
HFD3_k127_4083078_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004511 301.0
HFD3_k127_4083078_3 4Fe-4S binding domain K00338,K12143 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000001613 183.0
HFD3_k127_4083078_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000008752 96.0
HFD3_k127_4083078_5 Belongs to the complex I subunit 6 family K00339 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000003769 92.0
HFD3_k127_410420_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 3.287e-299 943.0
HFD3_k127_410420_1 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000002986 202.0
HFD3_k127_410420_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000001252 192.0
HFD3_k127_4112946_0 COG2801 Transposase and inactivated derivatives K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006021 382.0
HFD3_k127_4112946_1 transposase activity K07483,K07497 - - 0.000000000000000000000001711 109.0
HFD3_k127_4114055_0 DNA ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004381 520.0
HFD3_k127_4114055_1 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008783 470.0
HFD3_k127_4114055_2 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000001013 115.0
HFD3_k127_4122185_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.000000000000000000000000000000000000000000000000000001145 199.0
HFD3_k127_4122185_1 Mov34 MPN PAD-1 family K21140 - 3.13.1.6 0.0000000000000000000000000003134 122.0
HFD3_k127_4122185_2 PFAM thiamineS protein K03636 - - 0.00000000000000000000000001446 111.0
HFD3_k127_4122185_3 aminopeptidase activity - - - 0.0000000009595 64.0
HFD3_k127_4139334_0 Cytochrome C assembly protein K02198,K04016 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 543.0
HFD3_k127_4139334_1 Cytochrome C assembly protein K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000003716 227.0
HFD3_k127_4139334_2 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.00000000000000000000000000000006646 132.0
HFD3_k127_4139334_3 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 GO:0003674,GO:0003824,GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - 0.0000000000000003113 85.0
HFD3_k127_4139334_4 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.00008172 47.0
HFD3_k127_4142527_0 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 332.0
HFD3_k127_4142527_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003373 260.0
HFD3_k127_4142527_2 Transposase proposed to express due to -1 translational frameshift at the sequence 5'-AAAAAC-3' - - - 0.000000000000001868 78.0
HFD3_k127_4145110_0 PFAM NADP oxidoreductase coenzyme F420-dependent K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 292.0
HFD3_k127_4145110_1 metal-dependent phosphohydrolase HD region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 297.0
HFD3_k127_4145110_10 a CheY-like receiver domain and a - - - 0.0000000002249 63.0
HFD3_k127_4145110_12 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.0000001245 60.0
HFD3_k127_4145110_2 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005602 254.0
HFD3_k127_4145110_3 PFAM dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000003923 246.0
HFD3_k127_4145110_4 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001579 233.0
HFD3_k127_4145110_5 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000008041 231.0
HFD3_k127_4145110_6 HD domain - - - 0.000000000000000000000000000000006109 133.0
HFD3_k127_4145110_7 Adenylate guanylate cyclase catalytic domain protein K01768 - 4.6.1.1 0.000000000000000000000000000004868 126.0
HFD3_k127_4145110_8 - - - - 0.0000000000000000000000001425 109.0
HFD3_k127_4145110_9 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000000001657 79.0
HFD3_k127_4169796_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 8.747e-197 625.0
HFD3_k127_4169796_1 Peptidase C26 K07010 - - 0.0000000000000000000000000000000000004117 150.0
HFD3_k127_4169796_2 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.000000000000000000000000002198 125.0
HFD3_k127_4171575_0 metallopeptidase activity - - - 0.0000000000000002536 92.0
HFD3_k127_4193302_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001074 257.0
HFD3_k127_4193302_1 PFAM extracellular solute-binding protein family 1 K02040 - - 0.0000000000000000000000000000000000001093 153.0
HFD3_k127_4193302_2 - - - - 0.0000000000000001758 90.0
HFD3_k127_4193302_3 Uncharacterized conserved protein (DUF2277) - - - 0.00000000000002093 77.0
HFD3_k127_4209281_0 PFAM Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 336.0
HFD3_k127_4209281_1 C-type lectin (CTL) or carbohydrate-recognition domain (CRD) - - - 0.00000000000000000000000000449 119.0
HFD3_k127_4209281_2 Fibronectin type 3 domain - - - 0.000000000000000000007049 104.0
HFD3_k127_4220650_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 4.423e-212 681.0
HFD3_k127_4220650_1 CHASE3 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 309.0
HFD3_k127_4220650_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000003785 199.0
HFD3_k127_4220650_3 Belongs to the peptidase S33 family - - - 0.000002124 57.0
HFD3_k127_4220650_4 Helix-turn-helix XRE-family like proteins - - - 0.00001542 50.0
HFD3_k127_4244979_0 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 345.0
HFD3_k127_4244979_1 PFAM oxidoreductase domain protein K00010 - 1.1.1.18,1.1.1.369 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001407 279.0
HFD3_k127_4244979_2 ABC transporter permease K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001962 251.0
HFD3_k127_4244979_3 COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000001384 199.0
HFD3_k127_4244979_4 Xylose isomerase-like TIM barrel K03335 - 4.2.1.44 0.000000000000000000000000000000000000000000000001577 181.0
HFD3_k127_4256438_0 Amidohydrolase family K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000691 446.0
HFD3_k127_4256438_1 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004503 319.0
HFD3_k127_4256438_2 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000002372 205.0
HFD3_k127_4256438_3 methyltransferase K21459 - 2.1.1.301 0.000000000000000000000000000000000000002556 157.0
HFD3_k127_4256438_4 Major facilitator Superfamily - - - 0.000000000000000004655 99.0
HFD3_k127_4276116_0 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007455 386.0
HFD3_k127_4276116_2 Alpha/beta hydrolase family - - - 0.00000000002096 68.0
HFD3_k127_4282356_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 3.588e-229 732.0
HFD3_k127_4282356_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 488.0
HFD3_k127_4282356_2 CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004324 283.0
HFD3_k127_4282356_3 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000443 233.0
HFD3_k127_4282356_4 - - - - 0.0000000000000000000000000000000000004015 144.0
HFD3_k127_4282356_5 Thioesterase superfamily protein - - - 0.000000000000000000000000007129 118.0
HFD3_k127_4292724_0 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 521.0
HFD3_k127_4292724_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 379.0
HFD3_k127_4292724_2 Ethanolamine utilisation protein EutA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000321 305.0
HFD3_k127_4292724_3 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000002117 221.0
HFD3_k127_4292724_4 Ornithine cyclodeaminase K01750 - 4.3.1.12 0.0000000000000002101 83.0
HFD3_k127_4292724_5 Major Facilitator Superfamily - - - 0.000002855 59.0
HFD3_k127_4292724_6 Regulatory protein GntR HTH - - - 0.0005003 45.0
HFD3_k127_4293392_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008982 469.0
HFD3_k127_4293392_1 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 306.0
HFD3_k127_4293392_2 Negative regulator of - - - 0.0000000000000000000000000000000000000000000000000000000000000051 237.0
HFD3_k127_4293392_3 ribosome binding K02860 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000000000000002489 129.0
HFD3_k127_4293392_4 Diguanylate cyclase - - - 0.0000000000000000000000000003706 121.0
HFD3_k127_4293392_5 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000003458 108.0
HFD3_k127_4293392_6 KH domain K06960 - - 0.00000000000000003357 90.0
HFD3_k127_4317450_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 GO:0000731,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0019985,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042276,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 3.863e-230 752.0
HFD3_k127_4317450_1 Methyltransferase small domain - - - 0.000000000000000000000000000000000000000000000000000000000003228 221.0
HFD3_k127_4317450_2 Type VI secretion system effector, Hcp K11903 - - 0.0000000000000000000000000000000000000000000000000000025 204.0
HFD3_k127_4317450_3 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000009546 188.0
HFD3_k127_4317450_4 Type VI secretion system effector, Hcp K11903 - - 0.000000000000000000000000000000007954 140.0
HFD3_k127_4346543_0 CAAX prenyl protease N-terminal, five membrane helices - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 444.0
HFD3_k127_4346543_1 oxygen carrier activity K07216 - - 0.000000000000385 76.0
HFD3_k127_4346543_2 SMART Transport-associated and nodulation region - - - 0.00000002413 64.0
HFD3_k127_4358960_0 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009144 280.0
HFD3_k127_4358960_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0030312,GO:0032259,GO:0034641,GO:0035999,GO:0036211,GO:0040007,GO:0042084,GO:0042085,GO:0042558,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0050667,GO:0051186,GO:0071704,GO:0071944,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000007792 224.0
HFD3_k127_4358960_2 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000004368 215.0
HFD3_k127_4358960_3 Formiminotransferase-cyclodeaminase - - - 0.000000000000000000000001593 109.0
HFD3_k127_4366006_0 YCII-related domain K09780 - - 0.000000000000000000000000000123 124.0
HFD3_k127_4366006_1 Chromate transporter K07240 - - 0.00000000000000000007677 101.0
HFD3_k127_4366006_2 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000008985 83.0
HFD3_k127_4366006_3 COG2059 Chromate transport protein ChrA K07240 - - 0.00005216 52.0
HFD3_k127_4383186_0 MgsA AAA+ ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 482.0
HFD3_k127_4383186_1 ATPase domain predominantly from Archaea K06921 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004952 284.0
HFD3_k127_4383186_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000000000000000000000002938 207.0
HFD3_k127_4383186_3 Transglycosylase - - - 0.000000000000000000000000000000000000000000000000000183 195.0
HFD3_k127_4383186_4 Transglycosylase associated protein - - - 0.0000000000000000000001334 101.0
HFD3_k127_4383186_5 DNA-binding transcription factor activity K03892 - - 0.000000000000001101 82.0
HFD3_k127_4436012_0 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 301.0
HFD3_k127_4436012_2 CsbD-like - - - 0.00000006157 55.0
HFD3_k127_4436012_3 - - - - 0.000001171 52.0
HFD3_k127_4436012_4 EamA-like transporter family - - - 0.000004929 52.0
HFD3_k127_4452824_0 ABC 3 transport family K09819 - - 0.0000000000000000000000000000000000000000000000000000000009125 212.0
HFD3_k127_4452824_1 Abc transporter K09817,K09820,K11710,K19973 - 3.6.3.35 0.00000000000000000000000000000000000000000000000000004177 203.0
HFD3_k127_4452824_2 Zinc-uptake complex component A periplasmic K02077,K09818 - - 0.00000000000000000000000000000001718 132.0
HFD3_k127_4454403_0 succinate dehydrogenase, flavoprotein subunit K00239 GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363 1.3.5.1,1.3.5.4 2.6e-267 835.0
HFD3_k127_4454403_1 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 396.0
HFD3_k127_4454403_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 293.0
HFD3_k127_4454403_3 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000231 261.0
HFD3_k127_4454403_4 Cytochrome b(C-terminal)/b6/petD - - - 0.000000000000000000000000000000000000000000001149 173.0
HFD3_k127_4454403_5 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000001873 177.0
HFD3_k127_4454403_6 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000004715 148.0
HFD3_k127_4454403_7 cheY-homologous receiver domain - - - 0.0000000000000000000001179 108.0
HFD3_k127_4454403_8 PFAM Rieske 2Fe-2S domain K02636 - 1.10.9.1 0.00000000000000002152 90.0
HFD3_k127_4454403_9 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.00005241 55.0
HFD3_k127_4481494_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 352.0
HFD3_k127_4481494_1 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000005587 249.0
HFD3_k127_4481494_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000001396 73.0
HFD3_k127_4498872_0 Biotin carboxylase C-terminal domain K01968 - 6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008264 469.0
HFD3_k127_4498872_1 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.0000000000003766 71.0
HFD3_k127_4509331_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 374.0
HFD3_k127_4509331_1 phosphate starvation-inducible protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004233 325.0
HFD3_k127_4509331_10 ferrous iron binding K06990,K15755 - - 0.00000003483 63.0
HFD3_k127_4509331_2 Methylates ribosomal protein L11 K02687 - - 0.0000000000000000000000000000000000000000000000000000000005047 212.0
HFD3_k127_4509331_3 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019478,GO:0019752,GO:0043436,GO:0043530,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046144,GO:0046395,GO:0046416,GO:0046436,GO:0055130,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 - 0.0000000000000000000000000000000000002832 143.0
HFD3_k127_4509331_4 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000005372 140.0
HFD3_k127_4509331_5 SMART Metal-dependent phosphohydrolase, HD region K07037 - - 0.000000000000000000000000000002242 137.0
HFD3_k127_4509331_6 Yqey-like protein K09117 - - 0.000000000000000000000000001461 121.0
HFD3_k127_4509331_7 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000001275 88.0
HFD3_k127_4509331_8 Ribosomal protein S21 K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000002944 79.0
HFD3_k127_4509331_9 Urate oxidase N-terminal - - - 0.000000004589 64.0
HFD3_k127_4547211_0 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000001864 215.0
HFD3_k127_4547211_1 - - - - 0.000000000000000000000000000000000000000008373 171.0
HFD3_k127_4547211_2 helix_turn_helix, cAMP Regulatory protein K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.0000000000000000000000000000003174 131.0
HFD3_k127_4547211_3 aldo keto reductase - - - 0.000000000000000000000001351 104.0
HFD3_k127_4552973_0 phosphonoacetaldehyde hydrolase activity K07025 - - 0.0000000000000000000000000000000000000000003506 167.0
HFD3_k127_4552973_1 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000003957 131.0
HFD3_k127_4552973_2 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000001675 113.0
HFD3_k127_4552973_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation - - - 0.0000001012 56.0
HFD3_k127_4552973_4 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00003916 48.0
HFD3_k127_4566364_0 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000515 419.0
HFD3_k127_4566364_1 PFAM Fructose-bisphosphate aldolase, class-I K01623 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000004144 245.0
HFD3_k127_4598292_0 Belongs to the binding-protein-dependent transport system permease family K01997,K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000943 327.0
HFD3_k127_4598292_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007436 313.0
HFD3_k127_4598292_2 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 304.0
HFD3_k127_4598292_3 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000557 291.0
HFD3_k127_4598292_4 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000003943 167.0
HFD3_k127_4598292_5 Dinitrogenase iron-molybdenum cofactor - - - 0.00000000000000000000000000006993 118.0
HFD3_k127_4598292_6 PFAM pyridoxamine 5'-phosphate oxidase-related - - - 0.0000000000000000000002408 102.0
HFD3_k127_4598292_7 Luciferase-like monooxygenase - - - 0.0000931 46.0
HFD3_k127_4606888_0 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000001403 230.0
HFD3_k127_4606888_1 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000001342 168.0
HFD3_k127_4606888_2 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000000003479 109.0
HFD3_k127_4606888_3 Sigma-70, region 4 - - - 0.00000000000000001592 88.0
HFD3_k127_4613760_0 ABC transporter, transmembrane region K06147 - - 3.505e-247 800.0
HFD3_k127_4613760_1 ABC transporter, transmembrane region K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 543.0
HFD3_k127_462208_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 4.849e-216 701.0
HFD3_k127_462208_1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000009113 239.0
HFD3_k127_462208_2 HAMP domain - - - 0.0000000000000000000000000000000000000000000008177 177.0
HFD3_k127_462208_3 ABC transporter K06158 - - 0.00000000000000000000000000000000006294 148.0
HFD3_k127_462208_4 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000237 141.0
HFD3_k127_462208_5 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000001771 134.0
HFD3_k127_462208_6 response regulator, receiver - - - 0.0000000000000003858 86.0
HFD3_k127_462208_7 Domain of unknown function (DUF4349) - - - 0.00005115 53.0
HFD3_k127_4643354_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008606 482.0
HFD3_k127_4643354_1 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 352.0
HFD3_k127_4643354_2 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.000000000000000000000000000000618 134.0
HFD3_k127_4663565_0 transferase activity, transferring glycosyl groups K09118,K13693,K21349 - 2.4.1.266,2.4.1.268 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009929 478.0
HFD3_k127_4663565_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000005139 289.0
HFD3_k127_4663565_2 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000006658 89.0
HFD3_k127_4673801_0 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001199 258.0
HFD3_k127_4673801_1 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000007173 217.0
HFD3_k127_4673801_2 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.000000000000000000000000000000000000000000000000000005656 199.0
HFD3_k127_4685215_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006324 295.0
HFD3_k127_4685215_1 Protein of unknown function (DUF421) - - - 0.0000000000000000000000000000000003531 138.0
HFD3_k127_4685215_2 Universal stress protein - - - 0.0000000002565 67.0
HFD3_k127_4693531_0 aminopeptidase activity - - - 0.000000000000000000000000001316 116.0
HFD3_k127_4693531_1 Conserved repeat domain - - - 0.00000000000000000000001673 115.0
HFD3_k127_4693531_2 Conserved repeat domain - - - 0.0000000007128 71.0
HFD3_k127_4693531_3 polysaccharide deacetylase K22278 - 3.5.1.104 0.000000005087 68.0
HFD3_k127_4696631_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006655 371.0
HFD3_k127_4696631_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009088 345.0
HFD3_k127_4696631_2 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001842 273.0
HFD3_k127_4696631_3 PFAM amine oxidase - - - 0.00000000000000000000000000000003545 143.0
HFD3_k127_4721889_0 PFAM amidohydrolase K01464 - 3.5.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 612.0
HFD3_k127_4721889_1 DinB family - - - 0.0000000000000000000009446 102.0
HFD3_k127_4721889_2 DinB family - - - 0.0000002301 59.0
HFD3_k127_4732381_0 PFAM molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008598 317.0
HFD3_k127_4732381_1 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000001471 133.0
HFD3_k127_4732381_2 - - - - 0.00000000000000009947 81.0
HFD3_k127_4732381_3 adenylate kinase activity - - - 0.00000000001328 65.0
HFD3_k127_4732381_4 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000002014 63.0
HFD3_k127_4736253_0 Two component transcriptional regulator, winged helix family K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003599 287.0
HFD3_k127_4736253_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000002799 162.0
HFD3_k127_4736253_2 DNA polymerase LigD, polymerase domain K01971 - 6.5.1.1 0.00000000000000000000000000000000009778 138.0
HFD3_k127_4736253_3 Hydrolase of the alpha beta-hydrolase K07020 - - 0.0000001747 63.0
HFD3_k127_4748292_0 Proline racemase K01777 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016855,GO:0018112,GO:0019752,GO:0036361,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0047661,GO:0050346,GO:0071704,GO:1901564 5.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 287.0
HFD3_k127_4748292_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000001882 254.0
HFD3_k127_4763320_0 RadC-like JAB domain K03630 - - 0.0000000000000000000000000000000000000000000000008284 183.0
HFD3_k127_4763320_1 belongs to the nudix hydrolase family - - - 0.000000000001307 81.0
HFD3_k127_4781396_0 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005235 259.0
HFD3_k127_4781396_1 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter MnhD K12137 - - 0.000000000000000000000000000000000000001229 157.0
HFD3_k127_4781396_2 subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali K05568 GO:0003674,GO:0005215,GO:0005451,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035725,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600 - 0.00000000000000000000000112 115.0
HFD3_k127_4781396_3 Hydrogenase 4 membrane K12140 - - 0.00000000000000000000003985 115.0
HFD3_k127_4793089_0 TIGRFAM RNA polymerase sigma-54 factor, RpoN K03092 - - 0.0000000000000000000000000000000000000000000000005155 185.0
HFD3_k127_4801290_0 PFAM regulatory protein LuxR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 486.0
HFD3_k127_4801290_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03605 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 332.0
HFD3_k127_4801290_2 Response regulator receiver K02479,K07692 - - 0.000000000000000000000000000000000000000000000000000000001805 207.0
HFD3_k127_4801290_3 helix_turn_helix, Lux Regulon K07684 - - 0.00000000009795 73.0
HFD3_k127_4801290_4 polysaccharide biosynthetic process K01992 GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0008150,GO:0009987,GO:0044764,GO:0046812,GO:0051704 - 0.000000103 65.0
HFD3_k127_4805454_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 479.0
HFD3_k127_4805454_1 Tetratricopeptide repeat - - - 0.00000000000000395 83.0
HFD3_k127_4805454_2 - - - - 0.0000000002398 70.0
HFD3_k127_4805454_3 - - - - 0.00000002753 62.0
HFD3_k127_4823640_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 390.0
HFD3_k127_4823640_1 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007421 316.0
HFD3_k127_4823640_2 Peptidase family M20/M25/M40 K02083,K06016 - 3.5.1.6,3.5.1.87,3.5.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000002253 245.0
HFD3_k127_4823640_3 urate oxidase activity K00365,K16838 - 1.7.3.3,4.1.1.97 0.000000000000000000000000000000000000000000000000000000000000000003239 244.0
HFD3_k127_4823640_4 Protein of unknown function (DUF3830) - - - 0.00000000000000000000000000000000000000000000000003354 192.0
HFD3_k127_4823640_5 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.000000000000000000000000000000000000000000000009647 182.0
HFD3_k127_4823640_6 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily K07127 - 3.5.2.17 0.00000000000000000000000009949 110.0
HFD3_k127_4823640_7 OHCU decarboxylase - - - 0.0000000000000000000002018 102.0
HFD3_k127_4823640_8 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.00000001037 59.0
HFD3_k127_4823640_9 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.0000008643 60.0
HFD3_k127_4840880_0 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000001958 94.0
HFD3_k127_4840880_1 involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein - - - 0.00002006 56.0
HFD3_k127_4848589_0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000002119 258.0
HFD3_k127_4848589_1 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000003857 179.0
HFD3_k127_4848589_2 PFAM CBS domain - - - 0.00000003031 56.0
HFD3_k127_4869331_0 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009623 471.0
HFD3_k127_4869331_1 COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K11618 - - 0.0000000000000000000000000000000000000000000000000000000000386 218.0
HFD3_k127_4869331_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000002336 142.0
HFD3_k127_4869331_3 Bacterial membrane protein, YfhO - - - 0.00000000003479 70.0
HFD3_k127_4875832_0 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005046 428.0
HFD3_k127_4875832_1 Phosphoenolpyruvate phosphomutase K01637 - 4.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 344.0
HFD3_k127_4875832_2 Sodium/calcium exchanger protein K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 329.0
HFD3_k127_4875832_3 Multicopper oxidase K04753 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001464 272.0
HFD3_k127_4876415_0 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 556.0
HFD3_k127_4876415_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000996 348.0
HFD3_k127_4876415_2 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 319.0
HFD3_k127_4876415_3 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 324.0
HFD3_k127_4876415_4 ABC transporter permease K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000001487 246.0
HFD3_k127_4876415_5 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000001719 239.0
HFD3_k127_4876415_6 PFAM Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000007654 153.0
HFD3_k127_4876415_7 Siderophore biosynthesis protein domain K00663 - 2.3.1.82 0.0000000000000000000000000007286 123.0
HFD3_k127_4876415_8 metal-dependent membrane protease K07052 - - 0.0000000000008175 78.0
HFD3_k127_4908548_0 metallopeptidase activity K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004557 351.0
HFD3_k127_4908548_1 Putative modulator of DNA gyrase - - - 0.000000000000000000000000000000000000000000000000000005929 210.0
HFD3_k127_4908548_2 PFAM Conserved TM helix repeat-containing protein - - - 0.00000000000000000000000000000000000000002188 175.0
HFD3_k127_4908548_3 - - - - 0.00000000000000000000000000000005347 135.0
HFD3_k127_4908548_4 CopC domain K14166 - - 0.000000000000000000000000005417 129.0
HFD3_k127_4908548_5 Ferric uptake regulator family K03711,K09825 - - 0.00000000000000000000000005226 113.0
HFD3_k127_4908548_6 PFAM Copper resistance D K07245 - - 0.00000000000000000000004015 105.0
HFD3_k127_4955931_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K00058,K03977 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 467.0
HFD3_k127_4955931_1 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000003333 278.0
HFD3_k127_4955931_10 Nickel-containing superoxide dismutase K00518 - 1.15.1.1 0.0000000000000000000000000000000006199 135.0
HFD3_k127_4955931_11 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000003648 128.0
HFD3_k127_4955931_12 Redoxin - - - 0.0000000000000000000000001324 109.0
HFD3_k127_4955931_13 Cysteine-rich secretory protein family - - - 0.00000000000000000000001201 116.0
HFD3_k127_4955931_14 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000008544 85.0
HFD3_k127_4955931_15 Catalyzes the dephosphorylation of D,L-glyceraldehyde 3- phosphate in vitro K07025 - - 0.0000000000001978 80.0
HFD3_k127_4955931_16 signal peptide processing - - - 0.000000000008247 76.0
HFD3_k127_4955931_17 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0033554,GO:0034599,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887 - 0.00000000001638 71.0
HFD3_k127_4955931_18 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000002772 51.0
HFD3_k127_4955931_19 transferase activity, transferring glycosyl groups K20276 - - 0.000009857 58.0
HFD3_k127_4955931_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000005068 241.0
HFD3_k127_4955931_20 domain protein K01179 - 3.2.1.4 0.00001172 58.0
HFD3_k127_4955931_21 mRNA catabolic process - - - 0.00003431 55.0
HFD3_k127_4955931_22 Sensory domain found in PocR K07315 - 3.1.3.3 0.0003512 47.0
HFD3_k127_4955931_3 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000193 233.0
HFD3_k127_4955931_4 RNA pseudouridylate synthase K06178,K06181 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.20,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000006278 219.0
HFD3_k127_4955931_5 deaminated base DNA N-glycosylase activity K03648,K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000287 190.0
HFD3_k127_4955931_6 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000196 160.0
HFD3_k127_4955931_7 metallopeptidase activity - - - 0.000000000000000000000000000000000000000007987 163.0
HFD3_k127_4955931_8 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000001676 153.0
HFD3_k127_4955931_9 PFAM phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000125 147.0
HFD3_k127_4961133_0 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 399.0
HFD3_k127_4961133_1 Quinolinate phosphoribosyl transferase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 342.0
HFD3_k127_4961133_2 Dehydrogenase reductase sdr K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001916 282.0
HFD3_k127_4961133_3 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000005642 219.0
HFD3_k127_4961133_4 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000849 128.0
HFD3_k127_4961133_5 - - - - 0.000000000000000000007215 96.0
HFD3_k127_4961133_6 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000006313 96.0
HFD3_k127_4961133_7 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000001696 69.0
HFD3_k127_4984321_0 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K15510 - 1.1.98.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005911 304.0
HFD3_k127_4984321_1 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 297.0
HFD3_k127_4984321_2 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009532 250.0
HFD3_k127_4984321_3 Conserved protein containing a Zn-ribbon-like motif - - - 0.00000000003635 64.0
HFD3_k127_4985019_0 Belongs to the aldehyde dehydrogenase family - - - 3.735e-207 654.0
HFD3_k127_4985019_1 Aminotransferase class-III K15372 - 2.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 468.0
HFD3_k127_4985019_2 Carbon-nitrogen hydrolase K01431 - 3.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 426.0
HFD3_k127_4985019_3 F420-dependent oxidoreductase, Rv1855c family - - - 0.00000000000000000000000000000000000000000000000000002429 202.0
HFD3_k127_4985019_4 Putative stress-induced transcription regulator - - - 0.000000000000000000000000000000000758 138.0
HFD3_k127_4985019_5 Glycosylase K05522 - 4.2.99.18 0.000000000000000000000000000003137 126.0
HFD3_k127_4985019_6 Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell - - - 0.00000000001327 70.0
HFD3_k127_4989759_0 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 344.0
HFD3_k127_4989759_1 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000006189 227.0
HFD3_k127_4989759_2 Tfp pilus assembly protein FimV - - - 0.00000000000000000000000000000000000000000000003621 178.0
HFD3_k127_4989759_3 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.0000000000001232 74.0
HFD3_k127_4989759_4 Uncharacterized protein conserved in bacteria (DUF2255) - - - 0.00004449 52.0
HFD3_k127_5006110_0 Beta-lactamase enzyme family - - - 0.00000000002573 76.0
HFD3_k127_5032656_0 tRNA binding K04566 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 410.0
HFD3_k127_5032656_1 C-terminal binding-module, SLH-like, of glucodextranase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 406.0
HFD3_k127_5032656_2 transferase activity, transferring glycosyl groups K02844 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0008653,GO:0008919,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0046527,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001807 294.0
HFD3_k127_5032656_3 FES K03575 - - 0.00000000000000000000000000000000000000000000405 168.0
HFD3_k127_5032656_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000002926 158.0
HFD3_k127_5032656_5 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 GO:0000049,GO:0000166,GO:0000287,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016020,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046983,GO:0070905,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.1.1.11 0.0000000000000000000000000000003277 128.0
HFD3_k127_5032656_6 Methyltransferase domain - - - 0.00000007391 63.0
HFD3_k127_5042610_0 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 350.0
HFD3_k127_5042610_1 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 301.0
HFD3_k127_5042610_2 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000007003 242.0
HFD3_k127_5042610_3 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000001192 234.0
HFD3_k127_5042610_4 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000000000208 211.0
HFD3_k127_5042610_5 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000002634 153.0
HFD3_k127_5052082_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004469 349.0
HFD3_k127_5052082_1 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000132 128.0
HFD3_k127_5052082_2 - - - - 0.00000000000002181 77.0
HFD3_k127_5052082_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000006878 75.0
HFD3_k127_5052082_4 helix_turn_helix, Lux Regulon - - - 0.000001493 58.0
HFD3_k127_5068769_0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005039 423.0
HFD3_k127_5068769_1 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 366.0
HFD3_k127_5068769_2 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000002602 144.0
HFD3_k127_5068769_3 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000002217 121.0
HFD3_k127_5068769_4 Helix-turn-helix domain, rpiR family - - - 0.0000000001983 65.0
HFD3_k127_5075273_0 Ribosomal protein S1 K02945,K03527,K07571 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003954 461.0
HFD3_k127_5083351_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 316.0
HFD3_k127_5083351_1 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases K02083 - 3.5.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000002512 284.0
HFD3_k127_5083351_2 Transcription regulator MerR DNA binding K21902 - - 0.00000000000000000000000000000000000000002476 156.0
HFD3_k127_5083351_3 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.00006771 53.0
HFD3_k127_5083694_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 2.34e-304 972.0
HFD3_k127_5083694_1 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000946 152.0
HFD3_k127_5083694_2 ATP-binding region, ATPase domain protein - - - 0.00009516 52.0
HFD3_k127_5083694_3 HD domain - - - 0.0005554 52.0
HFD3_k127_5094543_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 362.0
HFD3_k127_5094543_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K09699 - 2.3.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006141 327.0
HFD3_k127_5094543_2 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0071944,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.181 0.000000000000000000000000000000000000000000000005131 184.0
HFD3_k127_5094543_3 PFAM Transketolase central region K00167 - 1.2.4.4 0.0000000000000000000000000000000000000000698 153.0
HFD3_k127_5127133_0 GtrA-like protein K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000009161 228.0
HFD3_k127_5127133_1 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000001434 181.0
HFD3_k127_5127133_2 Acetyltransferase (GNAT) family - - - 0.00000000000000005302 95.0
HFD3_k127_5128066_0 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 321.0
HFD3_k127_5128066_1 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000006456 228.0
HFD3_k127_5128066_2 protein secretion K03116 - - 0.00000000001052 66.0
HFD3_k127_5128066_3 Putative zinc- or iron-chelating domain - - - 0.000004518 54.0
HFD3_k127_5128066_4 Type II secretion system (T2SS), protein F K12511 - - 0.0001929 53.0
HFD3_k127_5170487_0 ABC transporter transmembrane region K06147,K18889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008966 523.0
HFD3_k127_5170487_1 PFAM ABC transporter transmembrane region K06147,K18890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005317 387.0
HFD3_k127_5183504_0 5'-3' exonuclease - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001478 267.0
HFD3_k127_5183504_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000215 208.0
HFD3_k127_5193330_0 Dehydrogenase K07077 - - 8.46e-203 641.0
HFD3_k127_5193330_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 450.0
HFD3_k127_5193330_2 PFAM Sodium hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 323.0
HFD3_k127_5193330_3 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000001327 226.0
HFD3_k127_5193330_4 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000000018 183.0
HFD3_k127_5193330_5 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000006442 110.0
HFD3_k127_5193330_6 sulfur carrier activity - - - 0.00000000000000000000000214 104.0
HFD3_k127_5193330_7 Sulfurtransferase TusA - - - 0.00000000000000006242 89.0
HFD3_k127_5193330_8 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000008458 90.0
HFD3_k127_5199101_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004887 430.0
HFD3_k127_5199101_1 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008044 345.0
HFD3_k127_5199101_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000009707 242.0
HFD3_k127_5199101_3 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000002493 155.0
HFD3_k127_5199101_4 aminoglycoside hydroxyurea antibiotic resistance kinase K04343 - 2.7.1.72 0.000000000000000000000000000003612 129.0
HFD3_k127_5199101_5 Pfam:DUF59 - - - 0.000000000001005 72.0
HFD3_k127_5204210_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 314.0
HFD3_k127_5204210_1 EamA-like transporter family - - - 0.000000000000000008023 96.0
HFD3_k127_5204210_2 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000002091 60.0
HFD3_k127_5219580_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 445.0
HFD3_k127_5219580_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000487 341.0
HFD3_k127_5219580_2 Participates in initiation and elongation during chromosome replication K02314 GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 330.0
HFD3_k127_5219580_3 Short-chain dehydrogenase reductase SDR K01784,K12454 - 5.1.3.10,5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000001044 239.0
HFD3_k127_5219580_4 Probable zinc-ribbon domain - - - 0.0000000000000000000000000000001089 130.0
HFD3_k127_5219580_5 DUF218 domain - - - 0.00000000000000000000000000002857 124.0
HFD3_k127_5219580_6 cell adhesion involved in biofilm formation - - - 0.00000000000004932 79.0
HFD3_k127_5219580_7 Peptidase S24-like K13280 GO:0003674,GO:0003824,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:0140096,GO:1901564 3.4.21.89 0.00000000000008045 80.0
HFD3_k127_5219811_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1337.0
HFD3_k127_5219811_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 3.774e-286 894.0
HFD3_k127_5219811_2 Cysteine-rich secretory protein family - - - 0.000000000000000000000000000000000000000000000004528 184.0
HFD3_k127_5219811_3 Protein of unknown function (DUF1684) K09164 - - 0.00000000000000000005499 102.0
HFD3_k127_5219811_4 Pilus assembly protein CpaB K02279 - - 0.000000000072 72.0
HFD3_k127_5219811_5 PFAM TadE family protein - - - 0.000000008938 64.0
HFD3_k127_5223491_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 0.00000000000000000000000000000000000000000000008251 179.0
HFD3_k127_5223491_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) - - - 0.0000000000000000000000000000000000000000519 157.0
HFD3_k127_5223491_2 tryptophan synthase activity K01696 - 4.2.1.20 0.0000000000000006344 90.0
HFD3_k127_5231037_0 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000000000000000000002011 209.0
HFD3_k127_5231037_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000436 162.0
HFD3_k127_5231037_2 Hemerythrin hhe - - - 0.0000000000000000000000003032 113.0
HFD3_k127_5244884_0 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001625 271.0
HFD3_k127_5244884_1 recombinase XerD K04763 GO:0008150,GO:0040007 - 0.0000000000000000000000000000003991 135.0
HFD3_k127_5244884_2 Involved in the TonB-independent uptake of proteins K03641 - - 0.00000000000000006554 87.0
HFD3_k127_5294507_0 PFAM Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007359 258.0
HFD3_k127_5294507_1 Binding-protein-dependent transport system inner membrane component K02026,K05815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007096 266.0
HFD3_k127_5294507_2 regulatory protein, FmdB family - - - 0.000000000000000002383 88.0
HFD3_k127_5294507_3 TIGRFAM YihY family protein (not ribonuclease BN) K07058 - - 0.00000006037 64.0
HFD3_k127_5343473_0 F420-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000379 209.0
HFD3_k127_5343473_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000004689 199.0
HFD3_k127_5343473_2 Putative tRNA binding domain K06878 - - 0.0000000000000000000000000000000000000004474 158.0
HFD3_k127_5343473_3 PFAM Peptidase S24 S26A S26B, conserved region K03100 - 3.4.21.89 0.0000000000000000000000000000000001364 139.0
HFD3_k127_5343473_4 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000002177 128.0
HFD3_k127_5343473_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000001091 121.0
HFD3_k127_5343473_6 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.00000000000000000000000006126 123.0
HFD3_k127_5343473_7 Protein of unknown function (DUF971) - - - 0.00000000000000000004038 101.0
HFD3_k127_5356349_0 Oxidoreductase molybdopterin binding domain K00387,K07147 - 1.8.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 314.0
HFD3_k127_5356349_1 COG1472 Beta-glucosidase-related glycosidases K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000002577 217.0
HFD3_k127_5365885_0 Putative modulator of DNA gyrase K03568 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 362.0
HFD3_k127_5365885_1 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000003565 152.0
HFD3_k127_537762_0 Two component transcriptional regulator, winged helix family K07669,K07672 GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009268,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010446,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0023052,GO:0030312,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0035556,GO:0043254,GO:0044087,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000005012 259.0
HFD3_k127_537762_1 Histidine kinase K07653 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000009258 246.0
HFD3_k127_537762_2 - - - - 0.000000000218 70.0
HFD3_k127_538187_0 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 304.0
HFD3_k127_538187_1 NAD(P)-binding Rossmann-like domain K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000793 247.0
HFD3_k127_538187_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000013 243.0
HFD3_k127_538187_3 Thioesterase - - - 0.00000000000000000000000000000000000000000000000000000101 208.0
HFD3_k127_538187_4 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000007261 190.0
HFD3_k127_538187_5 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000004592 179.0
HFD3_k127_538187_6 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000003844 136.0
HFD3_k127_538187_7 nitrogen compound transport K02033,K02034,K15581 - - 0.0006324 48.0
HFD3_k127_539362_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 526.0
HFD3_k127_539362_1 Belongs to the ABC transporter superfamily K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007698 502.0
HFD3_k127_539362_2 Belongs to the ABC transporter superfamily K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 477.0
HFD3_k127_539362_3 PFAM extracellular solute-binding protein, family 5 K15580 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 461.0
HFD3_k127_539362_4 Binding-protein-dependent transport system inner membrane component K15581 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 292.0
HFD3_k127_539362_5 PFAM binding-protein-dependent transport systems inner membrane component K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004057 298.0
HFD3_k127_539362_6 ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000004613 153.0
HFD3_k127_539362_7 NlpC/P60 family K20742 - 3.4.14.13 0.00000000000000000000000000000003539 138.0
HFD3_k127_539362_8 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000001019 133.0
HFD3_k127_5395649_0 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 338.0
HFD3_k127_5395649_1 B12 binding domain K22491 - - 0.000000000000000000000000000000000000000000000000000006149 195.0
HFD3_k127_5395649_2 Response regulator receiver K02483,K07658,K07668 - - 0.00000000000000000000000000000000000000000008311 171.0
HFD3_k127_5395649_3 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000001622 179.0
HFD3_k127_5395649_4 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000002089 154.0
HFD3_k127_5395649_5 Domain of unknown function (DUF378) - - - 0.0000000000001398 74.0
HFD3_k127_5395649_6 Electron transfer DM13 - - - 0.00001613 51.0
HFD3_k127_5414233_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 515.0
HFD3_k127_5414233_1 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 300.0
HFD3_k127_5414233_10 HNH nucleases - - - 0.0000000000000000009054 97.0
HFD3_k127_5414233_2 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000001261 200.0
HFD3_k127_5414233_3 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000337 188.0
HFD3_k127_5414233_4 MaoC like domain K18290 - 4.2.1.56 0.0000000000000000000000000000000000000000000001644 174.0
HFD3_k127_5414233_5 Thioredoxin - - - 0.0000000000000000000000000000000000000000000003286 176.0
HFD3_k127_5414233_6 PFAM flavin reductase domain protein, FMN-binding K21297,K21727 - 1.5.1.36 0.000000000000000000000000000000000002917 149.0
HFD3_k127_5414233_7 quinone binding - - - 0.0000000000000000000000005393 115.0
HFD3_k127_5414233_8 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000001002 107.0
HFD3_k127_5419610_0 Belongs to the heme-copper respiratory oxidase family - - - 1.753e-216 685.0
HFD3_k127_5419610_1 PFAM Rieske 2Fe-2S domain protein - - - 0.0000000000000000000000000000000000000000000004355 179.0
HFD3_k127_5419610_2 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000001219 130.0
HFD3_k127_5419610_3 COG1290 Cytochrome b subunit of the bc complex - - - 0.00000000000000002589 87.0
HFD3_k127_5419610_4 Cytochrome C oxidase subunit II, periplasmic domain - - - 0.0001315 44.0
HFD3_k127_5428775_0 COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 588.0
HFD3_k127_5428775_1 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004029 248.0
HFD3_k127_5428775_2 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000001343 194.0
HFD3_k127_5428775_3 PFAM ABC transporter related - - - 0.0000000000000000000000000000000000000000000002404 171.0
HFD3_k127_5428775_4 Acetyltransferase (GNAT) family - - - 0.0000000000000000112 94.0
HFD3_k127_5428775_5 N-acetylglucosaminylinositol deacetylase activity K22135 - - 0.000000000000003279 80.0
HFD3_k127_5428775_7 GlcNAc-PI de-N-acetylase K22135 - - 0.0000003963 57.0
HFD3_k127_5438749_0 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 589.0
HFD3_k127_5438749_1 FR47-like protein - - - 0.0000000000000000000000000000000000002163 152.0
HFD3_k127_5438749_2 - - - - 0.000000000000000000002553 106.0
HFD3_k127_5438749_3 Ion transport 2 domain protein K10716 - - 0.0000000002745 73.0
HFD3_k127_5446676_0 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005375 440.0
HFD3_k127_5446676_1 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002784 302.0
HFD3_k127_5446676_2 membrane protein (DUF2078) K08982 - - 0.00000009437 57.0
HFD3_k127_5486797_0 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 344.0
HFD3_k127_5486797_1 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005599 296.0
HFD3_k127_5486797_2 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000002075 242.0
HFD3_k127_5488502_0 PFAM response regulator receiver K02282 - - 0.000000000000000000000000000000000000000000000000000000000000003263 222.0
HFD3_k127_5488502_1 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.00000000000000000000000000000000000000000001065 177.0
HFD3_k127_5488502_2 RIO1 family - - - 0.000000000000000000000000000000000000000642 160.0
HFD3_k127_5488502_3 RDD family - - - 0.0000000000000000000000001448 111.0
HFD3_k127_5488502_4 Peptidase A24A, prepilin type IV K02278 - 3.4.23.43 0.000000000006001 74.0
HFD3_k127_5516497_0 belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000001093 143.0
HFD3_k127_5516497_1 COG2217 Cation transport ATPase K17686 - 3.6.3.54 0.0000166 52.0
HFD3_k127_5532489_0 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000002104 167.0
HFD3_k127_5532489_1 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3 K02276 - 1.9.3.1 0.0000000000000000000000000000000000001093 153.0
HFD3_k127_5532489_2 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000008422 142.0
HFD3_k127_5532489_3 Electron transport protein SCO1 SenC K07152 - - 0.000000000000000000000000000000007577 145.0
HFD3_k127_5532489_4 EamA-like transporter family - - - 0.000000000000000000000683 110.0
HFD3_k127_5532489_5 negative regulation of transcription, DNA-templated - - - 0.000000000000000003878 89.0
HFD3_k127_5532489_6 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00003192 56.0
HFD3_k127_5543108_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 311.0
HFD3_k127_5572787_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 344.0
HFD3_k127_5572787_1 ATPase activity K16922 - - 0.000000000000000000000000000000000000000000000000801 199.0
HFD3_k127_5586717_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005617 549.0
HFD3_k127_5586717_1 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001616 285.0
HFD3_k127_5586717_2 phosphorelay signal transduction system K12132 - 2.7.11.1 0.000000000000000000000000000000000000000007388 173.0
HFD3_k127_5586717_3 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000001969 140.0
HFD3_k127_5586717_4 - - - - 0.000000000000000000000000000000002198 139.0
HFD3_k127_5586717_5 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000106 94.0
HFD3_k127_5633973_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007781 303.0
HFD3_k127_5633973_1 P-loop containing region of AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001415 270.0
HFD3_k127_5633973_10 Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides K03478 - 3.5.1.105 0.0000000000000000000000000000000000000000005235 173.0
HFD3_k127_5633973_11 Probable zinc-ribbon domain - - - 0.0000000000000000000000000000000000001353 145.0
HFD3_k127_5633973_12 pyridoxamine 5'-phosphate K07005 - - 0.0000000000000000000000000000000003038 144.0
HFD3_k127_5633973_13 BadF/BadG/BcrA/BcrD ATPase family - - - 0.000000000000000000000000000000000385 146.0
HFD3_k127_5633973_14 PFAM pyridoxamine 5'-phosphate oxidase-related - - - 0.0000000000000000000000000000000221 131.0
HFD3_k127_5633973_15 PFAM LmbE family protein K18455 - 3.5.1.115 0.00000000000000000000000000000003576 136.0
HFD3_k127_5633973_16 amine dehydrogenase activity K00504,K12132 - 1.14.17.3,2.7.11.1 0.0000000000000000000000001689 117.0
HFD3_k127_5633973_17 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.00000003619 64.0
HFD3_k127_5633973_18 Acetyltransferase (GNAT) family - - - 0.00000007314 65.0
HFD3_k127_5633973_19 Helix-turn-helix domain - - - 0.0007534 50.0
HFD3_k127_5633973_2 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000002738 276.0
HFD3_k127_5633973_3 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000006062 259.0
HFD3_k127_5633973_4 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.000000000000000000000000000000000000000000000000000000000000000000005992 252.0
HFD3_k127_5633973_5 SIS domain K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000006093 239.0
HFD3_k127_5633973_6 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000005732 209.0
HFD3_k127_5633973_7 hmm pf00144 - - - 0.00000000000000000000000000000000000000000000000000002287 200.0
HFD3_k127_5633973_8 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000006204 184.0
HFD3_k127_5633973_9 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000000004294 172.0
HFD3_k127_5635884_0 Creatinase/Prolidase N-terminal domain K01271,K01274 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 354.0
HFD3_k127_5635884_1 Proton-conducting membrane transporter K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009991 351.0
HFD3_k127_5647278_0 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000001643 252.0
HFD3_k127_5647278_1 Hydrolase, TatD family K03424 - - 0.000000000000000000000000000000000000000000005491 170.0
HFD3_k127_5647278_2 extracellular polysaccharide biosynthetic process K13582 - - 0.00000000000000000000002699 110.0
HFD3_k127_5648588_0 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004017 285.0
HFD3_k127_5648588_1 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000002125 192.0
HFD3_k127_5652772_0 belongs to the sigma-70 factor family K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 459.0
HFD3_k127_5652772_1 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001881 280.0
HFD3_k127_5652772_2 PFAM ABC transporter related K01990,K16907 - - 0.00000000000000000000000000000000000000000000000000000000000001474 220.0
HFD3_k127_5652772_3 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000002403 171.0
HFD3_k127_5652772_4 - - - - 0.0000000000000000000000000000000000000001691 160.0
HFD3_k127_5652772_5 YCII-related domain - - - 0.000000000000000000000006429 113.0
HFD3_k127_5652772_6 YCII-related domain - - - 0.000000000000000000006787 98.0
HFD3_k127_5652772_7 Sigma-70 region 2 K03088 - - 0.00000000000000001115 89.0
HFD3_k127_5652772_8 deoxyhypusine monooxygenase activity - - - 0.0000000000000001654 93.0
HFD3_k127_5652772_9 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.0000000000004666 72.0
HFD3_k127_5669448_0 Tripartite tricarboxylate transporter TctA family K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 472.0
HFD3_k127_5669448_1 PFAM ABC transporter related K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 399.0
HFD3_k127_5669448_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008672 374.0
HFD3_k127_5669448_3 COG0530 Ca2 Na antiporter K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009076 265.0
HFD3_k127_5669448_4 Tripartite tricarboxylate transporter family receptor K07795 - - 0.0000000000000000000000000000000000000000000000000000000000000000001843 244.0
HFD3_k127_5669448_5 PFAM basic membrane lipoprotein K07335 - - 0.000000000000000000000000000000000000000000000000000000000000001423 230.0
HFD3_k127_5669448_6 cell envelope-related transcriptional attenuator - - - 0.000000000000000000000000000000000000000000000000003487 202.0
HFD3_k127_5669448_7 Tripartite tricarboxylate transporter TctB family - - - 0.0000000003249 69.0
HFD3_k127_5676853_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004165 464.0
HFD3_k127_5676853_1 TIGRFAM hydrolase, TatD family K03424 - - 0.00000000000000000000000000000000000000000000000000000001384 207.0
HFD3_k127_5676853_2 Peptidase family M28 - - - 0.00000000000000000000000000000003182 147.0
HFD3_k127_5676853_3 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000352 140.0
HFD3_k127_5676853_4 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000002038 121.0
HFD3_k127_5696007_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000002934 207.0
HFD3_k127_5696007_1 HD domain - - - 0.0000000000000000000000000000000000000000000000000001471 205.0
HFD3_k127_5696007_2 SMART Signal transduction response regulator, receiver region - - - 0.000000000000000000000000000000000000000000089 174.0
HFD3_k127_5696007_3 regulator - - - 0.0000000000000000000000000000003471 132.0
HFD3_k127_5696007_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K19694 - - 0.000000000000000000000000000001501 123.0
HFD3_k127_5696007_5 PFAM response regulator receiver K02483,K07658,K07668 - - 0.000000000000000000000000001787 115.0
HFD3_k127_5696007_6 VTC domain - - - 0.000000000002646 78.0
HFD3_k127_5765021_0 Cys/Met metabolism PLP-dependent enzyme K01739,K01761 - 2.5.1.48,4.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000152 282.0
HFD3_k127_5765021_1 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000001303 227.0
HFD3_k127_5765021_2 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000001927 169.0
HFD3_k127_5765021_3 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000006942 147.0
HFD3_k127_5765021_4 PspC domain - - - 0.0000000000000001005 86.0
HFD3_k127_5765021_5 - - - - 0.0000000007095 70.0
HFD3_k127_5772129_0 Enoyl-CoA hydratase K07539,K18570 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008438 418.0
HFD3_k127_5772129_1 S-(hydroxymethyl)glutathione dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 383.0
HFD3_k127_5772129_10 Predicted integral membrane protein (DUF2269) - - - 0.00000000002721 76.0
HFD3_k127_5772129_2 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 335.0
HFD3_k127_5772129_3 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000001245 267.0
HFD3_k127_5772129_4 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001562 268.0
HFD3_k127_5772129_5 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000248 274.0
HFD3_k127_5772129_6 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000002024 216.0
HFD3_k127_5772129_7 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000009773 206.0
HFD3_k127_5772129_8 Enoyl-CoA hydratase K07537 - 4.2.1.100 0.0000000000000000000000000000000000000009011 168.0
HFD3_k127_5772129_9 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.000000000002927 68.0
HFD3_k127_5790008_0 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000008945 171.0
HFD3_k127_5790008_1 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000001073 149.0
HFD3_k127_5793583_0 - - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000001453 162.0
HFD3_k127_5793583_1 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000331 81.0
HFD3_k127_580563_0 Creatinase/Prolidase N-terminal domain K01271,K01274 - 3.4.13.9 0.00000000000000000000000000185 119.0
HFD3_k127_580563_1 Small hydrophilic plant seed protein - - - 0.000000000000000000000000159 120.0
HFD3_k127_580563_2 Lytic transglycolase K03642 - - 0.000000000000002403 85.0
HFD3_k127_580563_3 Sortase family K07284 - 3.4.22.70 0.00003361 54.0
HFD3_k127_5810669_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 563.0
HFD3_k127_5810669_1 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000005691 229.0
HFD3_k127_5810669_2 Protein of unknown function DUF47 K02039,K07220 - - 0.0000000000000000000000000000000000000000000000003153 183.0
HFD3_k127_5816404_0 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 366.0
HFD3_k127_5816404_1 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 360.0
HFD3_k127_5816404_2 ligase activity - - - 0.00000000000000000000000000000000005301 137.0
HFD3_k127_5831899_0 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 492.0
HFD3_k127_5831899_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000001578 212.0
HFD3_k127_5831899_2 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus K00341 - 1.6.5.3 0.00000000000000000000000000000002512 133.0
HFD3_k127_5842115_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 466.0
HFD3_k127_5842115_1 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000003377 226.0
HFD3_k127_5843873_0 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000001609 87.0
HFD3_k127_5850976_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.148e-221 700.0
HFD3_k127_5850976_1 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000006401 254.0
HFD3_k127_5850976_2 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000000000000001326 106.0
HFD3_k127_5850976_3 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000000415 63.0
HFD3_k127_5850976_4 DinB family - - - 0.0009052 49.0
HFD3_k127_5868823_0 ECF sigma factor K03088 - - 0.00000000000000000000000000000000000000000000001079 179.0
HFD3_k127_5868823_1 Ferric reductase like transmembrane component - - - 0.00000000000000000000000004311 118.0
HFD3_k127_5868823_2 Anti-sigma-K factor rskA - - - 0.0004763 51.0
HFD3_k127_5869802_0 galactose-1-phosphate uridylyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 372.0
HFD3_k127_5869802_1 PFAM aspartate ornithine carbamoyltransferase, Asp Orn-binding region K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 349.0
HFD3_k127_5869802_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 362.0
HFD3_k127_5869802_3 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000003624 214.0
HFD3_k127_5869802_4 Peptidase, M23 - - - 0.0000000000000000000000000000000001962 141.0
HFD3_k127_5869802_5 NUDIX domain K03574 - 3.6.1.55 0.000002302 55.0
HFD3_k127_5882584_0 Peptidase dimerisation domain - - - 2.131e-198 629.0
HFD3_k127_5882584_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000899 403.0
HFD3_k127_5882584_2 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001292 251.0
HFD3_k127_5882584_3 Putative tRNA binding domain K06878 - - 0.00000000000000000000000000000000000000004094 161.0
HFD3_k127_5882584_4 Protein of unknown function (DUF971) - - - 0.0000000000000000000007766 103.0
HFD3_k127_5882584_5 Protein of unknown function (DUF3105) - - - 0.00000000000000005381 93.0
HFD3_k127_5884100_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 321.0
HFD3_k127_5884100_1 beta-1,4-mannooligosaccharide phosphorylase K20885 - 2.4.1.339,2.4.1.340 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009523 314.0
HFD3_k127_5884100_2 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002038 290.0
HFD3_k127_5884100_3 Highly conserved protein containing a thioredoxin domain K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000005908 253.0
HFD3_k127_5884100_4 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0000000000000000000000000000000000004571 153.0
HFD3_k127_5901912_0 pyruvate phosphate dikinase K01007 - 2.7.9.2 1.011e-213 692.0
HFD3_k127_5901912_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009169 550.0
HFD3_k127_5901912_10 ROK family K00845 - 2.7.1.2 0.00000000338 64.0
HFD3_k127_5901912_11 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000007388 68.0
HFD3_k127_5901912_12 Binds directly to 16S ribosomal RNA K02968 - - 0.000001973 53.0
HFD3_k127_5901912_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 452.0
HFD3_k127_5901912_3 Belongs to the phosphoglycerate kinase family K00927 GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 419.0
HFD3_k127_5901912_4 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 309.0
HFD3_k127_5901912_5 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000964 285.0
HFD3_k127_5901912_6 ABC transporter, transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000002057 188.0
HFD3_k127_5901912_7 PFAM ROK family protein K00845 - 2.7.1.2 0.000000000000000000000000000000000212 143.0
HFD3_k127_5901912_8 translation initiation factor activity - - - 0.000000000000003267 84.0
HFD3_k127_5901912_9 - - - - 0.00000000003641 76.0
HFD3_k127_5904917_0 Gas vesicle synthesis protein GvpL/GvpF - - - 0.000000000002542 77.0
HFD3_k127_5904917_1 Gas vesicle protein - - - 0.00001542 50.0
HFD3_k127_5904917_2 Gas vesicle synthesis protein GvpL/GvpF - - - 0.00008558 54.0
HFD3_k127_5905525_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 451.0
HFD3_k127_5905525_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0004048,GO:0004049,GO:0004425,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0016829,GO:0016830,GO:0016831,GO:0016833,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042401,GO:0042430,GO:0042435,GO:0042451,GO:0042455,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046219,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657,GO:1901659,GO:1902494 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 303.0
HFD3_k127_5905525_2 Carbamoyl-phosphate synthase L chain, ATP binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000296 279.0
HFD3_k127_5905525_3 Peptidase C26 K01658,K01664 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000004645 213.0
HFD3_k127_5905525_4 Peptidase M50 - - - 0.000000000000000000000000000000000264 151.0
HFD3_k127_5905525_5 Domain of unknown function (DUF4395) - - - 0.000000000000002731 86.0
HFD3_k127_5905525_6 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000001736 84.0
HFD3_k127_5905525_7 Domain of unknown function (DUF1992) - - - 0.0000004615 59.0
HFD3_k127_5908298_0 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 376.0
HFD3_k127_5908298_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00282 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004939 372.0
HFD3_k127_5908298_2 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000003267 167.0
HFD3_k127_5956002_0 - - - - 0.0000000000000000000000000000000000000000000000000003173 203.0
HFD3_k127_5956002_1 Shikimate kinase - - - 0.000000000000000000000000000000000000000000001214 170.0
HFD3_k127_5976755_0 ABC transporter K06020 - 3.6.3.25 1.813e-201 634.0
HFD3_k127_5976755_1 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 408.0
HFD3_k127_5976755_2 PFAM Integral membrane protein TerC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 292.0
HFD3_k127_5976755_3 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000003929 108.0
HFD3_k127_5980853_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - 2.16e-249 781.0
HFD3_k127_5980853_1 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000002226 76.0
HFD3_k127_5984678_0 glutathione-regulated potassium exporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 392.0
HFD3_k127_5984678_1 COGs COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004485 387.0
HFD3_k127_5984678_2 PFAM amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002927 271.0
HFD3_k127_5984678_3 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000008296 208.0
HFD3_k127_5984678_4 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000000000000000007662 154.0
HFD3_k127_5984678_5 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000007217 164.0
HFD3_k127_5984678_6 transcriptional regulator K13641 - - 0.000000009342 63.0
HFD3_k127_5984678_7 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0005216 51.0
HFD3_k127_5984678_8 Carboxymuconolactone decarboxylase family - - - 0.0006958 50.0
HFD3_k127_6083317_0 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000001784 216.0
HFD3_k127_6083317_1 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000002641 198.0
HFD3_k127_6083317_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K00320 - 1.5.98.2 0.000000000000000000000000000009707 137.0
HFD3_k127_6083317_3 CAAX protease self-immunity K07052 - - 0.0000000000000000000000001026 115.0
HFD3_k127_6083317_4 5'-3' exonuclease - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0001562 45.0
HFD3_k127_6100208_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 552.0
HFD3_k127_6100208_1 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000001663 199.0
HFD3_k127_6119077_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835,K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 411.0
HFD3_k127_6119077_1 PFAM amidohydrolase K01464 - 3.5.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 317.0
HFD3_k127_6119077_2 Protein of unknown function (DUF1385) - - - 0.000000000001239 70.0
HFD3_k127_6143941_0 Tripartite tricarboxylate transporter TctA family K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 556.0
HFD3_k127_6143941_1 Sensor_kinase_SpoOB-type, alpha-helical domain K02476 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009774 467.0
HFD3_k127_6143941_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000097 411.0
HFD3_k127_6143941_3 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 298.0
HFD3_k127_6143941_4 transcriptional regulatory protein K02475 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001778 252.0
HFD3_k127_6143941_5 Tripartite tricarboxylate transporter family receptor K07795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001473 252.0
HFD3_k127_6143941_6 Metallo-beta-lactamase superfamily K13075 - 3.1.1.81 0.00000000000000000000000000000000000001901 159.0
HFD3_k127_6143941_7 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000001303 87.0
HFD3_k127_6147887_0 TIGRFAM fructose-1,6-bisphosphatase, class II K02446 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 389.0
HFD3_k127_6147887_1 Belongs to the glycerate kinase type-1 family K00865 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 296.0
HFD3_k127_6147887_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000001603 234.0
HFD3_k127_6147887_3 cyclohydrolase - - - 0.000007653 50.0
HFD3_k127_6148168_0 Cysteine synthase K01697,K01738,K12339 - 2.5.1.47,4.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 573.0
HFD3_k127_6148168_1 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760,K01761 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 488.0
HFD3_k127_6148168_2 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 433.0
HFD3_k127_6148168_3 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.0000000000002158 74.0
HFD3_k127_6148168_4 - - - - 0.0000001315 59.0
HFD3_k127_6150039_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005167 473.0
HFD3_k127_6150039_1 DivIVA protein K04074 - - 0.000000000000003177 76.0
HFD3_k127_6220628_0 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01995,K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009434 296.0
HFD3_k127_6220628_1 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 300.0
HFD3_k127_6220628_10 Putative zinc-finger - - - 0.000000001226 64.0
HFD3_k127_6220628_2 Belongs to the binding-protein-dependent transport system permease family K01997,K11956 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007987 294.0
HFD3_k127_6220628_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002131 292.0
HFD3_k127_6220628_4 RNA polymerase sigma factor K03088 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000001757 220.0
HFD3_k127_6220628_5 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000008724 203.0
HFD3_k127_6220628_6 FES K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000002022 199.0
HFD3_k127_6220628_7 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000005119 207.0
HFD3_k127_6220628_8 transcriptional regulator - - - 0.00000000000000000000001162 104.0
HFD3_k127_6329840_0 Alpha-2-macroglobulin family K06894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 324.0
HFD3_k127_6336229_0 Telomere recombination K07566 - 2.7.7.87 0.000000000000000000000000000000000006732 147.0
HFD3_k127_6336229_1 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000001003 135.0
HFD3_k127_6336229_2 Methyltransferase small domain K02493 - 2.1.1.297 0.00000000001249 68.0
HFD3_k127_6336229_3 Interconversion of serine and glycine K00600 GO:0000741,GO:0003674,GO:0003824,GO:0004372,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005911,GO:0006730,GO:0006996,GO:0006997,GO:0007275,GO:0007623,GO:0008150,GO:0008152,GO:0009506,GO:0009553,GO:0009555,GO:0009559,GO:0009561,GO:0009987,GO:0010035,GO:0010038,GO:0010197,GO:0016020,GO:0016043,GO:0016740,GO:0016741,GO:0016742,GO:0030054,GO:0030154,GO:0032501,GO:0032502,GO:0042221,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046686,GO:0048229,GO:0048284,GO:0048511,GO:0048856,GO:0048869,GO:0050896,GO:0055044,GO:0071840,GO:0071944 2.1.2.1 0.0000000002542 62.0
HFD3_k127_6348928_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 2.222e-244 767.0
HFD3_k127_6348928_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 411.0
HFD3_k127_6348928_2 enoyl-CoA hydratase isomerase family protein K13766 - 4.2.1.18 0.0000000000000000000000000000000000000000001456 169.0
HFD3_k127_6348928_3 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000006333 158.0
HFD3_k127_6348928_4 Major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000002139 151.0
HFD3_k127_6348928_5 cyclic nucleotide binding K01420,K10914 - - 0.000000000000000000000000000000000002987 146.0
HFD3_k127_6348928_6 MaoC domain protein dehydratase K00634,K17865 - 2.3.1.19,4.2.1.55 0.000000000000000000000000000002572 132.0
HFD3_k127_6348928_7 PFAM regulatory protein, ArsR K21903 - - 0.0000000241 61.0
HFD3_k127_6348928_8 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0001586 53.0
HFD3_k127_6354261_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 433.0
HFD3_k127_6354261_1 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 366.0
HFD3_k127_6354261_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 341.0
HFD3_k127_6354261_3 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000004493 232.0
HFD3_k127_6354261_4 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.000000000000000000000000000001632 127.0
HFD3_k127_6362809_0 Catalyzes the transfer of a methyl group to L- homocysteine resulting in methionine formation. The physiological methyl donor is K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 396.0
HFD3_k127_6362809_1 Putative cell wall binding repeat 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 307.0
HFD3_k127_6362809_2 PFAM magnesium chelatase ChlI subunit K07391 - - 0.000000000000000000000000000000000000000000000000000000000597 214.0
HFD3_k127_6362809_3 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.00000000000000000000000000000000000000000002439 169.0
HFD3_k127_6362809_4 redox protein regulator of disulfide bond formation - - - 0.0000000000000000000000000000000000000000001625 175.0
HFD3_k127_6362809_5 Protein of unknown function (DUF2723) - - - 0.0000000000000000000000000008971 129.0
HFD3_k127_6362809_6 Belongs to the UPF0102 family K07460 - - 0.00000000000404 71.0
HFD3_k127_6375864_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K12952 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 539.0
HFD3_k127_6375864_1 breast cancer carboxy-terminal domain K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000007812 254.0
HFD3_k127_6381327_0 pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000637 452.0
HFD3_k127_6381327_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679,K01744 - 4.2.1.2,4.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000842 445.0
HFD3_k127_6381327_2 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000306 286.0
HFD3_k127_6381327_3 - - - - 0.0000000000000000000000000000001147 139.0
HFD3_k127_6381327_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768,K09565 - 5.2.1.8 0.00000000000000000000000002897 123.0
HFD3_k127_6381327_5 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000002024 100.0
HFD3_k127_6382173_0 Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure - - - 0.00000000000000000000000008308 108.0
HFD3_k127_6382173_1 Gas vesicle protein K - - - 0.0000000000000000000000005479 109.0
HFD3_k127_6382173_2 Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth - - - 0.000000000000000000000004219 105.0
HFD3_k127_6382173_3 protein histidine kinase activity K03407,K07678 - 2.7.13.3 0.00000001338 64.0
HFD3_k127_6382173_4 Gas vesicle synthesis protein GvpL/GvpF - - - 0.0000466 52.0
HFD3_k127_6390888_0 ABC transporter K06147,K18890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 419.0
HFD3_k127_6390888_1 Dodecin K09165 - - 0.0000000000000000009058 88.0
HFD3_k127_6394251_0 Type II/IV secretion system protein K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000007297 247.0
HFD3_k127_6394251_1 bacterial-type flagellum organization - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.0000001434 63.0
HFD3_k127_6394251_2 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.0000008074 57.0
HFD3_k127_639464_0 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000001715 217.0
HFD3_k127_639464_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000002809 207.0
HFD3_k127_639464_2 PFAM glycosyl transferase group 1 K15521 - 2.4.1.250 0.000000000000000000000000000000000000000000002929 171.0
HFD3_k127_6408106_0 Putative neutral zinc metallopeptidase K07054 GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782 316.0
HFD3_k127_6408106_1 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 311.0
HFD3_k127_6408106_10 Two component transcriptional regulator, winged helix family K10697 - - 0.0004054 48.0
HFD3_k127_6408106_2 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005832 279.0
HFD3_k127_6408106_3 Belongs to the Pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000002137 206.0
HFD3_k127_6408106_4 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.0000000000000000000000000000000000000000000000000000002872 199.0
HFD3_k127_6408106_5 AAA domain - - - 0.0000000000000000000000000000000000000000001516 164.0
HFD3_k127_6408106_6 carboxylic acid catabolic process - - - 0.000000000000000000000000000000000000000001478 168.0
HFD3_k127_6408106_7 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000001769 118.0
HFD3_k127_6408106_8 His Kinase A (phosphoacceptor) domain - - - 0.000000000003663 75.0
HFD3_k127_6408106_9 helix_turn_helix, Lux Regulon - - - 0.0001766 51.0
HFD3_k127_6409089_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 473.0
HFD3_k127_6409089_1 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 442.0
HFD3_k127_6409089_2 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 311.0
HFD3_k127_6409089_3 COG0437 Fe-S-cluster-containing hydrogenase components 1 K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003261 246.0
HFD3_k127_6409089_4 - - - - 0.00000000000000000000000000000000000000000002346 170.0
HFD3_k127_6418286_0 PFAM aminotransferase class I and II K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007557 498.0
HFD3_k127_6418286_1 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 347.0
HFD3_k127_6418286_2 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003335 248.0
HFD3_k127_6418286_3 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000001681 228.0
HFD3_k127_6418286_4 Protein of unknown function (DUF554) K07150 - - 0.00000000000000000000000000000000000000000000000000000000005267 226.0
HFD3_k127_6418286_5 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.0000000000000000000000000000000000000002229 162.0
HFD3_k127_6418286_6 Peptidase_C39 like family - - - 0.000000000000000000000003495 116.0
HFD3_k127_6418286_7 PFAM TadE family protein - - - 0.0000038 56.0
HFD3_k127_6424007_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 515.0
HFD3_k127_6424007_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 380.0
HFD3_k127_6424007_2 - - - - 0.000000000000000000004182 102.0
HFD3_k127_6435897_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005717 509.0
HFD3_k127_6435897_1 Belongs to the ABC transporter superfamily K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004881 394.0
HFD3_k127_6435897_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 368.0
HFD3_k127_6435897_3 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006042 308.0
HFD3_k127_6435897_4 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.00000000000000000000000000000000000000000000000000000000001269 214.0
HFD3_k127_6435897_5 Haloacid dehalogenase-like hydrolase - GO:0003674,GO:0003824,GO:0003850,GO:0004346,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0044237,GO:0050308,GO:0050309 - 0.0000000000000000000000000000000000000000000000000000001234 206.0
HFD3_k127_6435897_6 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000002217 128.0
HFD3_k127_6435897_7 DUF218 domain - - - 0.0000006957 60.0
HFD3_k127_6442106_0 - - - - 0.000000000000000001605 100.0
HFD3_k127_6442106_1 - - - - 0.00000000003788 67.0
HFD3_k127_6443289_0 membrane K13277,K15125,K15539 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005894 474.0
HFD3_k127_6443289_1 cell adhesion involved in biofilm formation K13735 - - 0.000000001124 73.0
HFD3_k127_6447623_0 Thiamine pyrophosphate enzyme, central domain K03336 - 3.7.1.22 2.578e-249 799.0
HFD3_k127_6447623_1 pfkB family carbohydrate kinase K03338 - 2.7.1.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003879 377.0
HFD3_k127_6447623_2 Xylose isomerase-like TIM barrel K03335 - 4.2.1.44 0.0000000000000000000000000000000000000000000000006889 180.0
HFD3_k127_6447623_3 KduI/IolB family K03337 - 5.3.1.30 0.000000000000000000000076 108.0
HFD3_k127_6449725_0 Amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000256 251.0
HFD3_k127_6449725_1 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000245 194.0
HFD3_k127_6449725_2 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000001 138.0
HFD3_k127_6462228_0 Transporter associated domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004523 470.0
HFD3_k127_6462228_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002672 244.0
HFD3_k127_6462228_2 Phospholipase D. Active site motifs. K06131 - - 0.00000000000000000000000000000000000000000001706 172.0
HFD3_k127_6479001_0 FeS assembly protein SufB K07033,K09014 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - 6.854e-210 661.0
HFD3_k127_6479001_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009049 374.0
HFD3_k127_6479001_2 Uncharacterized protein family (UPF0051) K09015 - - 0.00000000000000000000000000000000000000000000000000000000000008533 241.0
HFD3_k127_6479001_3 SUF system FeS assembly protein, NifU family K04488 - - 0.0000000000000000000000000000000000000000007456 166.0
HFD3_k127_6479001_4 D-alanyl-D-alanine carboxypeptidase K07260 - 3.4.17.14 0.000000000000000000000000000000000000000003025 171.0
HFD3_k127_6479001_5 Beta-lactamase - - - 0.000000000000000000000000000003437 127.0
HFD3_k127_6479001_6 of nitrite reductase and ring-hydroxylating K05710 - - 0.00000000000000000002078 105.0
HFD3_k127_6518983_0 Binding-protein-dependent transport system inner membrane component K02011,K02063 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 368.0
HFD3_k127_6518983_1 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000003348 130.0
HFD3_k127_6521554_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 529.0
HFD3_k127_6521554_1 aromatic amino acid beta-eliminating lyase threonine aldolase K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 409.0
HFD3_k127_6521554_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 GO:0002097,GO:0002098,GO:0002143,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.8.1.13 0.0000000000000001519 88.0
HFD3_k127_6529292_0 PFAM Short-chain dehydrogenase reductase SDR K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 290.0
HFD3_k127_6529292_1 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000264 253.0
HFD3_k127_6529292_2 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000001774 160.0
HFD3_k127_6529292_3 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000003974 136.0
HFD3_k127_6529292_4 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.4.23.36 0.00000000000000000001736 104.0
HFD3_k127_6529292_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458,K14660 - 2.3.1.179 0.000000000000000002144 85.0
HFD3_k127_6529292_6 - - - - 0.000000007754 62.0
HFD3_k127_6586539_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002407 280.0
HFD3_k127_6586539_1 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000001459 115.0
HFD3_k127_6586539_2 Uncharacterized ACR, COG1399 K07040 GO:0008150,GO:0040007 - 0.0000000000000000004144 92.0
HFD3_k127_6586539_3 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000008412 79.0
HFD3_k127_6586539_4 Immunoglobulin-like domain of bacterial spore germination - - - 0.0000002148 62.0
HFD3_k127_6595327_0 TadE-like protein - - - 0.00000001307 66.0
HFD3_k127_6595327_1 PFAM amino acid-binding ACT domain protein - - - 0.000007312 51.0
HFD3_k127_6601576_0 PFAM glycosyl hydrolase BNR repeat-containing protein - - - 0.0 1384.0
HFD3_k127_6601576_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 329.0
HFD3_k127_6601576_2 Hydroxymethylglutaryl-CoA lyase K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007767 272.0
HFD3_k127_6601576_3 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000004384 217.0
HFD3_k127_6601576_4 3-demethylubiquinone-9 3-O-methyltransferase activity K03428 - 2.1.1.11 0.0000000000000000000000000000000000000000000008094 175.0
HFD3_k127_6606471_0 PFAM glycosyl transferase, family 51 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005057 440.0
HFD3_k127_6606471_1 Protein of unknown function (DUF3494) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003159 261.0
HFD3_k127_6606471_2 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 GO:0005575,GO:0005576 - 0.000000000000000000000000000000000000000000000000000000000001274 216.0
HFD3_k127_6606471_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000003826 139.0
HFD3_k127_6606471_4 PFAM Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000003823 118.0
HFD3_k127_6606471_5 - - - - 0.00000000000000000224 87.0
HFD3_k127_6606471_6 - K07092 - - 0.000119 49.0
HFD3_k127_6616149_0 Phage shock protein A, PspA K03969 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003026 263.0
HFD3_k127_6616149_1 TPM domain - - - 0.000000000000000000000000000000000000000000000000000000000008519 231.0
HFD3_k127_6646798_0 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 311.0
HFD3_k127_6646798_1 Protein of unknown function (DUF2089) - - - 0.000000000000000000000000000000004406 132.0
HFD3_k127_6646798_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0040007,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.000000000003663 67.0
HFD3_k127_6646798_3 - - - - 0.0000007628 57.0
HFD3_k127_6646798_4 Putative adhesin - - - 0.0001338 54.0
HFD3_k127_6672910_0 ATPase associated with various cellular activities, AAA_3 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009739 279.0
HFD3_k127_6672910_1 Drug exporters of the RND superfamily K06994 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001084 259.0
HFD3_k127_6672910_2 Domain of unknown function (DUF4350) - - - 0.0000000000000000000001652 111.0
HFD3_k127_6672910_3 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.00000000000192 78.0
HFD3_k127_6672910_4 Domain of unknown function (DUF4129) - - - 0.00006146 56.0
HFD3_k127_669408_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.49e-253 791.0
HFD3_k127_669408_1 Response regulator containing a CheY-like receiver domain and a GGDEF domain K02488 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 0.000000000000000000000000000000000007515 142.0
HFD3_k127_669408_2 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000003226 135.0
HFD3_k127_6694167_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 596.0
HFD3_k127_6694167_1 Protein kinase domain K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000003893 224.0
HFD3_k127_6694167_2 Glucose-6-phosphate dehydrogenase subunit - - - 0.00000000000000000000000000000000000000000001341 178.0
HFD3_k127_6694167_3 Dolichyl-phosphate-mannose-protein mannosyltransferase K00728 - 2.4.1.109 0.00000000000000000000000000000000000000004331 174.0
HFD3_k127_6694167_4 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000001514 138.0
HFD3_k127_6694167_5 phosphatidylinositol metabolic process K13671 - - 0.000000000000000000000000000001344 139.0
HFD3_k127_6694167_6 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000002671 124.0
HFD3_k127_6694167_7 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000274 96.0
HFD3_k127_672320_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006868 329.0
HFD3_k127_672320_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002556 245.0
HFD3_k127_672320_10 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000002276 97.0
HFD3_k127_672320_11 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000001074 64.0
HFD3_k127_672320_2 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.000000000000000000000000000000000000000000000000000000000001875 219.0
HFD3_k127_672320_3 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000006877 218.0
HFD3_k127_672320_4 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000006157 202.0
HFD3_k127_672320_5 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000001834 197.0
HFD3_k127_672320_6 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000005273 187.0
HFD3_k127_672320_7 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000004504 153.0
HFD3_k127_672320_8 YbbR-like protein - GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 - 0.000000000000000000000000000001173 139.0
HFD3_k127_672320_9 ribosomal protein l17 K02879 - - 0.000000000000000000000000004104 118.0
HFD3_k127_6742981_0 transferase K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008088 404.0
HFD3_k127_6742981_1 Binding-protein-dependent transport system inner membrane component K02033,K15585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 390.0
HFD3_k127_6742981_2 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 332.0
HFD3_k127_6742981_3 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001547 284.0
HFD3_k127_6742981_4 Enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002123 284.0
HFD3_k127_6742981_5 beta-keto acid cleavage enzyme - - - 0.000000000000000000000000000000000000000000000000002268 200.0
HFD3_k127_6742981_6 beta-lactamase domain protein K13075 - 3.1.1.81 0.0000000000000000000000000000000000000000000004776 186.0
HFD3_k127_6742981_7 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000008185 66.0
HFD3_k127_6742981_8 cellulose binding - - - 0.00000004994 65.0
HFD3_k127_6747788_0 Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis K01705 GO:0003674,GO:0003824,GO:0004409,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006536,GO:0006553,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009066,GO:0009067,GO:0009085,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010106,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019725,GO:0019752,GO:0019878,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0071704,GO:0098771,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.36 0.000000000001156 71.0
HFD3_k127_6747788_1 BAAT / Acyl-CoA thioester hydrolase C terminal K06889 - - 0.00000325 59.0
HFD3_k127_6751383_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005883 525.0
HFD3_k127_6751383_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000009591 144.0
HFD3_k127_6751383_2 Belongs to the complex I subunit 6 family K05578 - 1.6.5.3 0.0000000000000000000008137 101.0
HFD3_k127_6751383_3 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K00340 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000004047 104.0
HFD3_k127_6803179_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 296.0
HFD3_k127_6803179_1 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000002044 240.0
HFD3_k127_6803179_2 Threonine dehydratase K01754 - 4.3.1.19 0.000000000000000000000000000000000000000001483 162.0
HFD3_k127_6803179_3 phosphoglycerate mutase K02226,K22316 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.73 0.000000000000000000000000000000000004329 144.0
HFD3_k127_6803179_5 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.00007083 53.0
HFD3_k127_6803179_6 Aminoglycoside phosphotransferase - - - 0.0004452 51.0
HFD3_k127_6813002_0 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000001131 223.0
HFD3_k127_6813002_1 PFAM Rhomboid family - - - 0.00000000000000000000000000000000000000000000000001879 187.0
HFD3_k127_6813002_2 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000003014 128.0
HFD3_k127_6813002_3 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000001211 56.0
HFD3_k127_6822035_0 Nitroreductase family - - - 0.000000000000000000000000000000000000000005661 160.0
HFD3_k127_6822035_1 PFAM Haloacid dehalogenase domain protein hydrolase - - - 0.000000000000000000000000000000000000001787 161.0
HFD3_k127_6822035_2 Domain of unknown function (DUF2088) - - - 0.000000000000000000004852 97.0
HFD3_k127_6851222_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 1.212e-248 779.0
HFD3_k127_6851222_1 PFAM Prolyl oligopeptidase family - - - 3.99e-236 757.0
HFD3_k127_6851222_10 SMART zinc finger CDGSH-type domain protein - - - 0.00000000004099 74.0
HFD3_k127_6851222_11 Glycosyltransferase family 87 - - - 0.00004361 56.0
HFD3_k127_6851222_2 TRAP transporter, 4TM 12TM fusion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 576.0
HFD3_k127_6851222_3 TRAP transporter solute receptor, TAXI family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003413 285.0
HFD3_k127_6851222_4 dUTPase K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000001963 182.0
HFD3_k127_6851222_5 PFAM Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000003567 181.0
HFD3_k127_6851222_6 PFAM thioesterase superfamily protein - - - 0.00000000000000000000000000000000000000000001115 169.0
HFD3_k127_6851222_7 Peptidase A4 family - - - 0.00000000000000000000000004876 117.0
HFD3_k127_6851222_8 Protein of unknown function (DUF2723) - - - 0.00000000000000000000000005275 123.0
HFD3_k127_6851222_9 Serine aminopeptidase, S33 K01055 - 3.1.1.24 0.0000000000000000000002271 106.0
HFD3_k127_694615_0 transcriptional regulator K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.0000000000000000000000000000000000003605 149.0
HFD3_k127_694615_1 cAMP-dependent protein kinase regulatory subunit K04739 GO:0000003,GO:0000166,GO:0000228,GO:0000785,GO:0000790,GO:0001932,GO:0001933,GO:0002831,GO:0002832,GO:0003674,GO:0004857,GO:0004860,GO:0004862,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005886,GO:0005952,GO:0006469,GO:0006950,GO:0006979,GO:0007154,GO:0008104,GO:0008150,GO:0008277,GO:0008603,GO:0009266,GO:0009267,GO:0009405,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009653,GO:0009892,GO:0009966,GO:0009968,GO:0009987,GO:0009991,GO:0010563,GO:0010570,GO:0010605,GO:0010639,GO:0010646,GO:0010648,GO:0016020,GO:0017076,GO:0019207,GO:0019210,GO:0019220,GO:0019222,GO:0019887,GO:0019954,GO:0022603,GO:0023051,GO:0023057,GO:0030154,GO:0030234,GO:0030291,GO:0030435,GO:0030436,GO:0030447,GO:0030448,GO:0030551,GO:0030552,GO:0030554,GO:0031279,GO:0031281,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0031667,GO:0031668,GO:0031669,GO:0031974,GO:0031981,GO:0032101,GO:0032102,GO:0032104,GO:0032105,GO:0032107,GO:0032108,GO:0032268,GO:0032269,GO:0032386,GO:0032388,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032879,GO:0032880,GO:0032991,GO:0033036,GO:0033043,GO:0033157,GO:0033554,GO:0033673,GO:0034305,GO:0034599,GO:0034605,GO:0034613,GO:0036094,GO:0036170,GO:0036180,GO:0040007,GO:0040008,GO:0042173,GO:0042221,GO:0042325,GO:0042326,GO:0042594,GO:0043085,GO:0043086,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043549,GO:0043934,GO:0043936,GO:0043937,GO:0043938,GO:0043943,GO:0043945,GO:0043949,GO:0043951,GO:0044092,GO:0044093,GO:0044182,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0045595,GO:0045597,GO:0045744,GO:0045761,GO:0045762,GO:0045786,GO:0045859,GO:0045881,GO:0045926,GO:0045936,GO:0046578,GO:0046580,GO:0046822,GO:0046824,GO:0046825,GO:0046827,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051049,GO:0051050,GO:0051056,GO:0051058,GO:0051094,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051174,GO:0051179,GO:0051222,GO:0051223,GO:0051246,GO:0051248,GO:0051338,GO:0051339,GO:0051348,GO:0051349,GO:0051445,GO:0051447,GO:0051641,GO:0051704,GO:0051716,GO:0051726,GO:0051783,GO:0051784,GO:0060255,GO:0060258,GO:0060341,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070201,GO:0070727,GO:0070887,GO:0071496,GO:0071900,GO:0071901,GO:0071944,GO:0080090,GO:0080134,GO:0090087,GO:0090316,GO:0097159,GO:0097271,GO:0097367,GO:0098772,GO:0106070,GO:0106072,GO:0110033,GO:0110034,GO:1900428,GO:1900429,GO:1900434,GO:1900435,GO:1900443,GO:1900444,GO:1901265,GO:1901363,GO:1902531,GO:1902532,GO:1902659,GO:1902660,GO:1903664,GO:1903666,GO:1903827,GO:1903829,GO:1904951,GO:2000241,GO:2000242,GO:2000479,GO:2000480 - 0.00000000000000000000000000000001767 136.0
HFD3_k127_694615_2 - - - - 0.00000000000000004556 92.0
HFD3_k127_6967697_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 4.2.1.33,4.2.1.35 3.866e-200 633.0
HFD3_k127_6967697_1 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005824 362.0
HFD3_k127_6967697_2 Alanine-glyoxylate amino-transferase K03710,K05825 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004177 306.0
HFD3_k127_6967697_3 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) - - - 0.000000000000000000000000000000000000000000000000000000000000000000009606 241.0
HFD3_k127_6967697_4 Prephenate dehydratase K04518,K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000003995 112.0
HFD3_k127_6978565_0 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004227 409.0
HFD3_k127_6978565_1 Aminotransferase K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005268 302.0
HFD3_k127_6978565_2 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000002007 173.0
HFD3_k127_6978565_3 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.00000000000000000000000000000000001762 152.0
HFD3_k127_6978565_4 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines K01476,K01480 - 3.5.3.1,3.5.3.11 0.00000000000000000000000166 113.0
HFD3_k127_6994738_0 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000001005 232.0
HFD3_k127_6994738_1 Two component transcriptional regulator, LuxR family - - - 0.000000000000000000000000000000000000000000000000000000000000001043 225.0
HFD3_k127_6994738_2 Stage II sporulation D domain protein K06381 - - 0.0000000000000000000000000000000000000000000003423 186.0
HFD3_k127_6994738_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07777 - 2.7.13.3 0.00000000000000000000000000000000000000008288 166.0
HFD3_k127_6994738_4 histidine kinase, dimerisation and phosphoacceptor region K07777 - 2.7.13.3 0.0000000000000000000000000000000000000001284 166.0
HFD3_k127_6994738_5 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000000005093 84.0
HFD3_k127_6994738_6 DinB superfamily - - - 0.000000000000005819 81.0
HFD3_k127_6994738_7 oligosaccharyl transferase activity - - - 0.00000000000001455 86.0
HFD3_k127_7002735_0 ECF sigma factor K03088 - - 0.0000000000000000000000000000000000005147 151.0
HFD3_k127_7002735_1 ThiF family K03148,K21029,K21147 - 2.7.7.73,2.7.7.80,2.8.1.11 0.000000000000000000000003027 103.0
HFD3_k127_7002735_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000008406 64.0
HFD3_k127_7006459_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 384.0
HFD3_k127_7006459_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008068 311.0
HFD3_k127_7006459_2 zinc metalloprotease K04771,K11749,K16922 GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0040007,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000006185 226.0
HFD3_k127_7006459_3 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000006772 224.0
HFD3_k127_7006459_4 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000002276 162.0
HFD3_k127_7006459_5 transport system, permease component K01992 - - 0.00000000000000000000000000000001221 145.0
HFD3_k127_7006459_6 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.0000000000000000000000000000001607 129.0
HFD3_k127_7006459_7 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000007294 126.0
HFD3_k127_7006459_8 DinB superfamily - - - 0.00009708 55.0
HFD3_k127_7006459_9 serine threonine protein kinase K12132 - 2.7.11.1 0.0005583 51.0
HFD3_k127_7013710_0 Belongs to the thiolase family K00626,K02615 - 2.3.1.174,2.3.1.223,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 488.0
HFD3_k127_7013710_1 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000047 342.0
HFD3_k127_7013710_10 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000002788 164.0
HFD3_k127_7013710_11 HD domain K07814 - - 0.000000000000000000000000000000000000002508 161.0
HFD3_k127_7013710_12 - K01992 - - 0.000000000003738 78.0
HFD3_k127_7013710_13 - - - - 0.000000000008777 75.0
HFD3_k127_7013710_2 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 291.0
HFD3_k127_7013710_3 extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003308 287.0
HFD3_k127_7013710_4 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002331 262.0
HFD3_k127_7013710_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004867 249.0
HFD3_k127_7013710_6 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K11963 - - 0.0000000000000000000000000000000000000000000000000000000000000004852 238.0
HFD3_k127_7013710_7 Branched-chain amino acid ATP-binding cassette transporter - - - 0.00000000000000000000000000000000000000000000000000000000000005806 235.0
HFD3_k127_7013710_8 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000002134 228.0
HFD3_k127_7013710_9 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000005925 224.0
HFD3_k127_70528_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 496.0
HFD3_k127_70528_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000006708 126.0
HFD3_k127_70528_2 Uncharacterized protein family UPF0016 - - - 0.00000000000000000000000000008526 120.0
HFD3_k127_70528_3 Ferric reductase like transmembrane component K17247 - - 0.0000000000000000002312 99.0
HFD3_k127_7061835_0 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007086 612.0
HFD3_k127_7061835_1 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005358 549.0
HFD3_k127_7061835_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000003351 192.0
HFD3_k127_7061835_3 PFAM TrkA-N domain protein K03499 - - 0.00000000000000000000000000000000000000000000001358 178.0
HFD3_k127_7061835_4 TrkA-N domain K03499 - - 0.0000000000000000000000000000000002354 141.0
HFD3_k127_7061835_5 Universal stress protein family - - - 0.00000000000000000000816 97.0
HFD3_k127_7061835_6 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000009366 52.0
HFD3_k127_7096991_0 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 339.0
HFD3_k127_7096991_1 Membrane K06384 - - 0.00000000000000000000000000000000000000000000000000000000000005039 231.0
HFD3_k127_7096991_2 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 GO:0005575,GO:0005576 - 0.0000000000000000000000000000002893 129.0
HFD3_k127_7096991_3 PFAM RDD domain containing protein - - - 0.0000000000000000000000000009721 130.0
HFD3_k127_7096991_4 ATPase associated with various cellular activities, AAA_3 K03924 - - 0.00000000000000002285 82.0
HFD3_k127_7096991_5 - - - - 0.0000000000000002617 92.0
HFD3_k127_7100780_0 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.00000000000005512 79.0
HFD3_k127_7100780_1 Periplasmic sensor domain K20956,K21021 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0032153,GO:0032879,GO:0033554,GO:0036460,GO:0040012,GO:0040013,GO:0042802,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051270,GO:0051271,GO:0051716,GO:0052621,GO:0065007,GO:0071944,GO:1902021,GO:1902201,GO:2000145,GO:2000146 2.7.7.65 0.00000000002457 74.0
HFD3_k127_7121957_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 508.0
HFD3_k127_7121957_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000001799 222.0
HFD3_k127_7121957_10 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0001873 50.0
HFD3_k127_7121957_2 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000000000000000000000001783 207.0
HFD3_k127_7121957_3 PFAM 60 kDa inner membrane insertion protein K03217 - - 0.00000000000000000000000000000000000000000000008401 184.0
HFD3_k127_7121957_4 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000001906 183.0
HFD3_k127_7121957_5 R3H domain protein K06346 - - 0.00000000000000000000000000000000007466 145.0
HFD3_k127_7121957_6 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000006538 136.0
HFD3_k127_7121957_7 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000001034 100.0
HFD3_k127_7121957_8 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000004356 68.0
HFD3_k127_7121957_9 Hemerythrin HHE cation binding domain - - - 0.000000000006848 71.0
HFD3_k127_7137322_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007076 399.0
HFD3_k127_7137322_1 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain K03520,K11177 - 1.17.1.4,1.2.5.3 0.000000000000000000000000002969 114.0
HFD3_k127_7187313_0 Enoyl-(Acyl carrier protein) reductase K00019 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 385.0
HFD3_k127_7187313_1 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000003604 235.0
HFD3_k127_7187458_0 N-acetylmuramoyl-L-alanine amidase - - - 0.000000000000000000000000000000001573 149.0
HFD3_k127_7187458_1 TIGRFAM amino acid adenylation domain - - - 0.000000001181 72.0
HFD3_k127_7222049_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 344.0
HFD3_k127_7222049_1 KR domain - - - 0.000000000000000000000000000000000000000000005816 173.0
HFD3_k127_7222049_2 Predicted integral membrane protein (DUF2269) - - - 0.00000000003233 65.0
HFD3_k127_7263541_0 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000114 258.0
HFD3_k127_7263541_1 ABC-2 type transporter - - - 0.000000000000000000000000000000000000001814 158.0
HFD3_k127_7263541_2 PFAM ABC-2 type transporter K01992 - - 0.00000000000000003621 93.0
HFD3_k127_7263541_3 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.0000000000003384 76.0
HFD3_k127_7264155_0 PFAM Cytochrome C - - - 0.0004547 51.0
HFD3_k127_7306742_0 Protein of unknown function (DUF3048) C-terminal domain - - - 0.0000000000000000000000000000000000000009428 169.0
HFD3_k127_7306742_1 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000437 123.0
HFD3_k127_7306742_2 Histidine kinase - - - 0.0000000000000000000005099 110.0
HFD3_k127_7324812_0 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 380.0
HFD3_k127_7324812_1 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 291.0
HFD3_k127_7324812_2 Hexapeptide repeat of succinyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000002073 231.0
HFD3_k127_7324812_3 Protein of unknown function (DUF421) - - - 0.000000000000000000000000000000000000003811 152.0
HFD3_k127_7345116_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 6.826e-197 627.0
HFD3_k127_7345116_1 Dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000007562 72.0
HFD3_k127_7356425_0 Penicillin-Binding Protein C-terminus Family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000433 497.0
HFD3_k127_7356425_1 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 358.0
HFD3_k127_7356425_2 PFAM luciferase family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 314.0
HFD3_k127_7408846_0 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 329.0
HFD3_k127_7408846_1 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.00000000000000000000000000000000000000000000000000000000007284 213.0
HFD3_k127_7427536_0 Ammonium Transporter Family K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 576.0
HFD3_k127_7427536_1 ATPases associated with a variety of cellular activities K16785,K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 511.0
HFD3_k127_7427536_2 ABC-type cobalt transport system, permease component K16925 - - 0.00000000000000000000000000000000000000000000000006 192.0
HFD3_k127_7427536_3 Cobalt transport protein K16785 - - 0.00000000000000000000000000000000000000000000769 184.0
HFD3_k127_7427536_4 PFAM Thiamin pyrophosphokinase, catalytic region K00949 - 2.7.6.2 0.000000000000000000000000000000000000001488 156.0
HFD3_k127_7454627_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 563.0
HFD3_k127_7454627_1 Zinc-binding dehydrogenase K00060 - 1.1.1.103 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 502.0
HFD3_k127_7454627_2 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008149 394.0
HFD3_k127_7454627_3 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01190 - 3.2.1.23 0.000000000000004601 78.0
HFD3_k127_7454627_4 spore germination - - - 0.00000000444 68.0
HFD3_k127_7454627_5 - - - - 0.0000475 55.0
HFD3_k127_7477939_0 Heat shock 70 kDa protein K04043 - - 1.613e-278 869.0
HFD3_k127_7477939_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001141 273.0
HFD3_k127_7477939_2 helix_turn_helix, cAMP Regulatory protein K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.00000000000000000000000000000000000000000004806 169.0
HFD3_k127_7477939_4 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.0000000000000000000000000000000000001174 148.0
HFD3_k127_7477939_5 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000004939 121.0
HFD3_k127_7477939_6 PFAM response regulator receiver K07657,K07658 - - 0.0000000000000000000001019 105.0
HFD3_k127_7477939_7 TRANSCRIPTIONal - - - 0.000000000000000005814 94.0
HFD3_k127_7526195_0 COG1053 Succinate dehydrogenase fumarate reductase, flavoprotein subunit K13796 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 450.0
HFD3_k127_7526195_1 TIGRFAM CitB domain protein K13795 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003806 281.0
HFD3_k127_7526195_2 'Phosphotransferase - - - 0.000000000000000000000000000000000000000000000000005448 199.0
HFD3_k127_7526195_3 OsmC-like protein K04063 - - 0.00000000000000000000000000000000000000146 152.0
HFD3_k127_7526195_4 Glycosyl hydrolase-like 10 - - - 0.0008709 49.0
HFD3_k127_7560772_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K16792 - 4.2.1.114 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004251 424.0
HFD3_k127_7560772_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01655 - 2.3.3.14 0.000000000000000000000000000000000000000000000000000000000000003364 220.0
HFD3_k127_7560772_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K16793 - 4.2.1.114 0.000000000000000000000000000000000000000000000003928 186.0
HFD3_k127_7560772_3 C-terminus of bacterial fibrinogen-binding adhesin K14194 - - 0.0004736 48.0
HFD3_k127_7579349_0 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001534 280.0
HFD3_k127_7579349_1 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 4.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000003058 258.0
HFD3_k127_7579349_2 Belongs to the DEAD box helicase family K05592 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003725,GO:0003727,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009987,GO:0010468,GO:0010501,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019439,GO:0022607,GO:0022613,GO:0022618,GO:0030312,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0032268,GO:0032270,GO:0032574,GO:0032575,GO:0033554,GO:0033592,GO:0034057,GO:0034248,GO:0034250,GO:0034458,GO:0034459,GO:0034622,GO:0034641,GO:0034655,GO:0042254,GO:0042255,GO:0042273,GO:0042623,GO:0043170,GO:0043487,GO:0043488,GO:0043489,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045934,GO:0046483,GO:0046700,GO:0048255,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070035,GO:0070417,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097617,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902369,GO:1902373,GO:1903311,GO:1903312,GO:2000112 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000002208 245.0
HFD3_k127_7620957_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 305.0
HFD3_k127_7620957_1 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000211 221.0
HFD3_k127_7620957_2 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050 - - 0.0000000000000000000000000000000000000000000000000000003932 203.0
HFD3_k127_7620957_3 Hydrolase - - - 0.0000000000000000000000000000000000000000000000000002316 194.0
HFD3_k127_7620957_4 Succinylglutamate desuccinylase aspartoacylase K06987 - - 0.00000000000000000000000000000000001734 153.0
HFD3_k127_7620957_5 Ethanolamine utilisation protein EutA - - - 0.00000000000000000000000000000000001999 142.0
HFD3_k127_7620957_6 chromate transport K07240 - - 0.000000000000000000000004391 109.0
HFD3_k127_7620957_7 chromate transport K07240 - - 0.00000007102 63.0
HFD3_k127_7620957_8 Abc-type nitrate sulfonate bicarbonate transport K15576 - - 0.000001561 61.0
HFD3_k127_7628527_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007115 400.0
HFD3_k127_7628527_1 PolyA polymerase K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 359.0
HFD3_k127_7628527_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 314.0
HFD3_k127_7628527_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.0000000000000000000000000000006707 139.0
HFD3_k127_7628527_4 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000005315 93.0
HFD3_k127_7642268_0 ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001535 248.0
HFD3_k127_7642268_1 esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003086 250.0
HFD3_k127_7642268_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000005897 217.0
HFD3_k127_7642268_3 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000001347 193.0
HFD3_k127_7642268_4 EamA-like transporter family - - - 0.0000000000003154 74.0
HFD3_k127_7645892_0 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001526 263.0
HFD3_k127_7645892_1 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000007405 171.0
HFD3_k127_7645892_2 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000009215 165.0
HFD3_k127_7645892_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000001909 164.0
HFD3_k127_7645892_4 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000002157 122.0
HFD3_k127_7645892_5 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000001125 103.0
HFD3_k127_7645892_6 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000002319 97.0
HFD3_k127_7707665_0 UvrD/REP helicase N-terminal domain K03657,K07465 - 3.6.4.12 1.6e-217 704.0
HFD3_k127_7707665_1 Elongation factor SelB, winged helix K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 496.0
HFD3_k127_7707665_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 353.0
HFD3_k127_7707665_3 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0090304,GO:0097056,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 327.0
HFD3_k127_7707665_4 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000002264 159.0
HFD3_k127_7721839_0 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564 - 0.00000000000000000000000000000000000000000008262 167.0
HFD3_k127_7721839_1 Fungal trichothecene efflux pump (TRI12) - - - 0.000000000000000000000000001438 120.0
HFD3_k127_7735530_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835,K01840 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 473.0
HFD3_k127_7735530_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003018 278.0
HFD3_k127_7735530_2 Bacterial phospho-glucose isomerase C-terminal SIS domain K15916 - 5.3.1.8,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000006433 263.0
HFD3_k127_7735530_3 PFAM NAD-dependent epimerase dehydratase K15856 - 1.1.1.281 0.000000000000000000000000000000000000000000000000000001494 203.0
HFD3_k127_7735530_4 Belongs to the ComB family K05979 - 3.1.3.71 0.000000000000000000000000000000000000001803 161.0
HFD3_k127_7735530_5 cheY-homologous receiver domain - - - 0.000000000000000000001059 103.0
HFD3_k127_7735530_6 NUDIX domain - - - 0.0009685 48.0
HFD3_k127_777805_0 Belongs to the enoyl-CoA hydratase isomerase family K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005055 478.0
HFD3_k127_777805_1 Thiolase, C-terminal domain K00632 - 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 420.0
HFD3_k127_777805_2 Acyl-CoA dehydrogenase, N-terminal K00248,K18244 - 1.3.8.1 0.00000000000000000000000000000000000000000005127 185.0
HFD3_k127_777805_3 LysE type translocator - - - 0.000000000000000000003945 99.0
HFD3_k127_779067_0 PFAM Endonuclease Exonuclease phosphatase K07004 - - 4.248e-243 788.0
HFD3_k127_779067_1 heat shock protein binding K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 305.0
HFD3_k127_779067_10 gas vesicle protein - - - 0.000000003694 61.0
HFD3_k127_779067_11 cheY-homologous receiver domain - - - 0.0003666 52.0
HFD3_k127_779067_2 carboxylic acid catabolic process K02549 GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.2.1.113 0.000000000000000000000000000000000000000000000000001422 186.0
HFD3_k127_779067_3 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000007332 173.0
HFD3_k127_779067_4 YceI-like domain - - - 0.0000000000000000000000000000000002114 140.0
HFD3_k127_779067_5 FAD binding domain K09471 - - 0.00000000000000000000005619 108.0
HFD3_k127_779067_6 His Kinase A (phosphoacceptor) domain - - - 0.000000000000003503 87.0
HFD3_k127_779067_7 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity K09471 - - 0.00000000000002009 77.0
HFD3_k127_779067_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000002301 69.0
HFD3_k127_779067_9 Cupredoxin-like domain - - - 0.000000000435 66.0
HFD3_k127_779835_0 Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 458.0
HFD3_k127_779835_1 PFAM Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000001338 185.0
HFD3_k127_779835_2 AraC-like ligand binding domain - - - 0.0000000000000000005438 91.0
HFD3_k127_779835_3 - - - - 0.000000000000000002548 98.0
HFD3_k127_779835_4 Bacterial regulatory proteins, tetR family - - - 0.000000000000002731 83.0
HFD3_k127_782145_0 Metal dependent phosphohydrolases with conserved 'HD' motif. K09163 - - 0.00000000000000000000000000000000000000000000000000000000000000000001288 246.0
HFD3_k127_782145_1 NUDIX domain - - - 0.000000000000000000000000000006951 124.0
HFD3_k127_782145_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000001228 61.0
HFD3_k127_782145_3 Sodium/hydrogen exchanger family K03316 - - 0.00007211 49.0
HFD3_k127_81877_0 Asparaginase K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007795 317.0
HFD3_k127_81877_1 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.0000000000000000000000000000000000000000000001387 181.0
HFD3_k127_81877_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000008691 147.0
HFD3_k127_81877_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000002635 111.0
HFD3_k127_81877_4 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0009338 49.0
HFD3_k127_823284_0 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 417.0
HFD3_k127_823284_1 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000002327 254.0
HFD3_k127_823284_2 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000001231 230.0
HFD3_k127_823284_3 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000005663 188.0
HFD3_k127_823284_4 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000004542 190.0
HFD3_k127_823284_5 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000006498 159.0
HFD3_k127_823284_6 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000003896 151.0
HFD3_k127_823284_7 - - - - 0.00000000000000000000000003026 113.0
HFD3_k127_823284_8 transcriptional regulator K03892 - - 0.0000000000000000001673 95.0
HFD3_k127_823284_9 - - - - 0.0000002359 62.0
HFD3_k127_852344_0 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008654 299.0
HFD3_k127_852344_1 4Fe-4S dicluster domain - - - 0.0000000000000000000002393 107.0
HFD3_k127_852344_2 Tricorn protease homolog - - - 0.000000000000000000002148 108.0
HFD3_k127_852344_3 Molybdopterin-guanine dinucleotide biosynthesis protein A K07141 - 2.7.7.76 0.00000000000000000001569 106.0
HFD3_k127_860473_0 ATPases associated with a variety of cellular activities K10041 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004886 276.0
HFD3_k127_860473_1 Amino acid ABC transporter substrate-binding protein K10039 - - 0.0000000000000000000000000000000000000000000000000007858 195.0
HFD3_k127_860473_2 Binding-protein-dependent transport system inner membrane component K10040 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000001896 184.0
HFD3_k127_860473_3 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K09971,K10040 - - 0.000000000000000000000000000000000000000000001272 175.0
HFD3_k127_870015_0 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007193 427.0
HFD3_k127_870015_1 multicopper oxidase type 3 K00368 - 1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005286 282.0
HFD3_k127_870015_2 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000003555 212.0
HFD3_k127_870015_3 Belongs to the HesB IscA family K15724 - - 0.000000000000000004119 87.0
HFD3_k127_870015_4 Hemerythrin HHE cation binding domain - - - 0.00000005966 62.0
HFD3_k127_870015_5 helix_turn_helix, Lux Regulon - - - 0.000001076 56.0
HFD3_k127_875873_0 peptidase dimerisation domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005865 481.0
HFD3_k127_875873_1 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009545 314.0
HFD3_k127_875873_2 benzoyl-CoA reductase K04112 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000005739 274.0
HFD3_k127_875873_3 benzoyl-CoA reductase K04113 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000167 268.0
HFD3_k127_875873_4 Two component transcriptional regulator, winged helix family - - - 0.0000000000000000000000001162 120.0
HFD3_k127_875873_5 LacY proton/sugar symporter - - - 0.0000000000000000000000003193 121.0
HFD3_k127_875873_6 Iron-containing redox enzyme - - - 0.0000001791 62.0
HFD3_k127_875873_7 general stress protein B in uncultured methanogenic archaeon (Q0W564) - - - 0.000006201 51.0
HFD3_k127_900749_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 418.0
HFD3_k127_900749_1 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 407.0
HFD3_k127_900749_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000257 244.0
HFD3_k127_900749_3 PFAM Chorismate mutase of the AroH class K06208 - 5.4.99.5 0.000000000000000000000000000000004706 143.0
HFD3_k127_900749_4 Prephenate dehydrogenase K00210,K04517 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12 0.0000000000000000000000006795 119.0
HFD3_k127_900749_5 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000007944 60.0
HFD3_k127_909433_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006297 302.0
HFD3_k127_909433_1 Ethanolamine utilisation protein EutA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002729 259.0
HFD3_k127_909433_2 FCD - - - 0.0000000000000000000008614 99.0
HFD3_k127_916552_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 399.0
HFD3_k127_916552_1 Carboxylesterase family K01066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007049 267.0
HFD3_k127_916552_2 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000149 79.0
HFD3_k127_916552_3 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.0000000009374 59.0
HFD3_k127_926015_0 TIGRFAM TRAP transporter, DctM subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003422 493.0
HFD3_k127_926015_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000002055 261.0
HFD3_k127_926015_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000002226 242.0
HFD3_k127_926015_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.3 0.0000000000000000000000000000000001939 138.0
HFD3_k127_926015_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000001566 135.0
HFD3_k127_926015_5 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000001197 120.0
HFD3_k127_928193_0 Cytochrome c K00412 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 435.0
HFD3_k127_928193_1 benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.00000000000000000000000000000000000000000000000000000000000000000000007776 257.0
HFD3_k127_928193_2 Acetyltransferase (GNAT) family - - - 0.000000000000000005115 89.0
HFD3_k127_941481_0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 310.0
HFD3_k127_941481_1 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.00000000000000000000000000000004862 133.0
HFD3_k127_941481_2 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000000000000556 100.0
HFD3_k127_941481_3 subunit of a heme lyase - - - 0.0000000000000000002353 100.0
HFD3_k127_941481_4 FecR protein - - - 0.0000000001351 74.0
HFD3_k127_941481_5 PFAM Cytochrome c assembly protein K02198 - - 0.00000002423 58.0
HFD3_k127_941481_6 protein conserved in bacteria - - - 0.0001317 54.0
HFD3_k127_941481_7 cellulose synthase K20543 - - 0.000399 53.0
HFD3_k127_964359_0 Uncharacterized protein family (UPF0051) K09014 - - 0.000000000000000000000000000000000000000000000004382 191.0
HFD3_k127_985577_0 ATPases associated with a variety of cellular activities K01990,K09689,K09691,K09693 - 3.6.3.38,3.6.3.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 343.0
HFD3_k127_985577_1 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000005125 139.0
HFD3_k127_985577_2 PIN domain - - - 0.0000000000000000000000125 108.0
HFD3_k127_985577_3 methyltransferase - - - 0.0000000000000000000007892 109.0
HFD3_k127_985577_4 Glycosyl transferases group 1 - - - 0.0000000000002002 82.0
HFD3_k127_985577_5 Ribbon-helix-helix protein, copG family - - - 0.0000004136 58.0
HFD3_k127_994669_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.612e-205 651.0
HFD3_k127_994669_1 adenylosuccinate lyase K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 454.0
HFD3_k127_994669_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 347.0
HFD3_k127_994669_3 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 353.0
HFD3_k127_994669_4 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 356.0
HFD3_k127_994669_5 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000006015 162.0
HFD3_k127_994669_6 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000001955 79.0