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Overview

ID MAG01697
Name HFD3_bin.40
Sample SMP0045
Taxonomy
Kingdom Bacteria
Phylum Zixibacteria
Class MSB-5A5
Order JAUVRN01
Family JAUVRN01
Genus DAIOGN01
Species
Assembly information
Completeness (%) 69.35
Contamination (%) 0.26
GC content (%) 63.0
N50 (bp) 4,843
Genome size (bp) 2,342,025

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2117

Gene name Description KEGG GOs EC E-value Score Sequence
HFD3_k127_1028036_0 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 460.0
HFD3_k127_1028036_1 Oxidoreductase family, NAD-binding Rossmann fold K13018 - 2.3.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 383.0
HFD3_k127_1028036_2 UDP-N-acetylglucosamine 2-epimerase activity K01791,K13019 - 5.1.3.14,5.1.3.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 321.0
HFD3_k127_1028036_3 Hexapeptide repeat of succinyl-transferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000005101 270.0
HFD3_k127_1028036_4 Polysaccharide biosynthesis protein - - - 0.0000000000003129 79.0
HFD3_k127_1033852_0 Protein kinase domain K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000006083 186.0
HFD3_k127_1033852_1 COG1592 Rubrerythrin - - - 0.0000003954 53.0
HFD3_k127_1037049_0 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000006607 188.0
HFD3_k127_1037049_1 Alg9-like mannosyltransferase family K05286 - - 0.0000000000000000000000000000000000000000000004377 182.0
HFD3_k127_1037049_2 Amidohydrolase family - - - 0.000000031 57.0
HFD3_k127_1037783_0 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 0.0 1230.0
HFD3_k127_1037783_1 MreB/Mbl protein K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006159 541.0
HFD3_k127_1037783_2 Permease YjgP YjgQ family protein K07091,K11720 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004468 430.0
HFD3_k127_1037783_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000257 250.0
HFD3_k127_1037783_4 MafB19-like deaminase K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000004377 217.0
HFD3_k127_1037783_5 PFAM HD domain K03698 - - 0.00000000000000000000000000000000000000000000000000000000001037 218.0
HFD3_k127_1037783_6 Predicted permease YjgP/YjgQ family K11720 - - 0.000000000000000000000000000000000155 150.0
HFD3_k127_1051721_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573,K12585 - - 3.19e-207 667.0
HFD3_k127_1051721_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 418.0
HFD3_k127_1051721_2 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006935 303.0
HFD3_k127_1051721_3 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000008095 129.0
HFD3_k127_1079063_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000001233 179.0
HFD3_k127_1096005_0 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 403.0
HFD3_k127_1096005_1 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000004072 158.0
HFD3_k127_1107901_0 Heat shock 70 kDa protein K04043 - - 2.337e-211 665.0
HFD3_k127_1107901_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0000988,GO:0000989,GO:0003674,GO:0003756,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010556,GO:0015035,GO:0015036,GO:0016020,GO:0016032,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0016989,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031326,GO:0032991,GO:0034641,GO:0034645,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0055114,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0140096,GO:0140110,GO:1901360,GO:1901576,GO:1903506,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006502 349.0
HFD3_k127_1117112_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 540.0
HFD3_k127_1117112_1 AAA ATPase, central domain protein K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006439 331.0
HFD3_k127_1117112_2 GlcNAc-PI de-N-acetylase K01463 - - 0.00000000000000000000000000000000000000000000001827 180.0
HFD3_k127_1117112_3 ERCC4 domain K10896 - - 0.000000000000000000005454 103.0
HFD3_k127_111718_0 Belongs to the DEAD box helicase family K05592,K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 508.0
HFD3_k127_111718_1 Evidence 5 No homology to any previously reported sequences K20952 - - 0.000000000000000001681 99.0
HFD3_k127_111718_2 PFAM SMP-30 Gluconolaconase - - - 0.000000000000005221 88.0
HFD3_k127_1120757_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006492 357.0
HFD3_k127_1120757_1 Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 327.0
HFD3_k127_1120757_2 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000311 278.0
HFD3_k127_1120757_3 acetoacetate metabolism regulatory protein AtoC K07714 K02481 - - 0.000000000000000000642 91.0
HFD3_k127_1120757_4 phosphorelay signal transduction system K02437 - - 0.0000000000000000008504 98.0
HFD3_k127_1131619_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 5.444e-218 680.0
HFD3_k127_1131619_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 523.0
HFD3_k127_1131619_2 Ribosomal protein L33 K02913 - - 0.0000000000000000008065 87.0
HFD3_k127_1131619_3 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000005268 55.0
HFD3_k127_1131861_0 PFAM MscS Mechanosensitive ion channel K22044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002215 266.0
HFD3_k127_1131861_1 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000007346 213.0
HFD3_k127_1131861_2 NlpC p60 family K19224,K21471 - - 0.00000000000000000000000000003316 123.0
HFD3_k127_1131861_3 UbiA prenyltransferase family K03179,K04040 - 2.5.1.133,2.5.1.39,2.5.1.62 0.00000000000000000000000000009838 129.0
HFD3_k127_1131861_4 Cytidylyltransferase family K00981 - 2.7.7.41 0.00000000000000000000000005784 113.0
HFD3_k127_1156191_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 437.0
HFD3_k127_1156191_1 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009208 383.0
HFD3_k127_1156191_2 PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000739 320.0
HFD3_k127_1156191_3 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 309.0
HFD3_k127_1156191_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000004486 177.0
HFD3_k127_1156191_5 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.000000000000000000000000003295 120.0
HFD3_k127_1156191_6 Translation initiation factor SUI1 K03113 - - 0.0000000000000000003224 101.0
HFD3_k127_1156191_7 Zinc-binding dehydrogenase - - - 0.000002438 49.0
HFD3_k127_1156191_8 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.00003912 54.0
HFD3_k127_1168275_0 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000000000000000000000000000000000000000000000000000002093 211.0
HFD3_k127_1168275_1 biopolymer transport protein K03559 - - 0.0000000000000000000000000000000000000000205 158.0
HFD3_k127_1168275_2 biopolymer transport protein - - - 0.00000000000000000000000000000001651 132.0
HFD3_k127_1168275_3 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.00000000000000000000000000000005819 143.0
HFD3_k127_1168275_4 Yip1 domain - - - 0.0000000000000000000000002359 115.0
HFD3_k127_1168275_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K15727 - - 0.0000000000000000002923 92.0
HFD3_k127_1168275_6 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000000000002099 81.0
HFD3_k127_1170508_0 PFAM regulatory protein LuxR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 285.0
HFD3_k127_1173132_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006408 574.0
HFD3_k127_1173132_1 Integral membrane sensor signal transduction histidine kinase K07709,K13924 - 2.1.1.80,2.7.13.3,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 383.0
HFD3_k127_1173132_2 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000001535 176.0
HFD3_k127_1173132_3 His Kinase A (phosphoacceptor) domain - - - 0.000001948 51.0
HFD3_k127_120306_0 PFAM SPFH domain Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 381.0
HFD3_k127_120306_1 Protein of unknown function, DUF255 K00943 - 2.7.4.9 0.00000000000001334 76.0
HFD3_k127_120306_2 PFAM Zinc finger TFIIB-type domain protein - - - 0.0002546 52.0
HFD3_k127_1207893_0 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000006085 225.0
HFD3_k127_1207893_1 cell adhesion K02456,K02650,K10924,K10925 - - 0.000000000000000000000000000000000000000000000000004744 188.0
HFD3_k127_1207893_2 cell adhesion K02456,K02650,K10924,K10925 - - 0.000000000000000000000000000000000006039 150.0
HFD3_k127_1207893_3 Protein of unknown function (DUF2723) - - - 0.000000000000000000000006423 118.0
HFD3_k127_1207969_0 PFAM NAD-dependent epimerase dehydratase K01784,K02473 - 5.1.3.2,5.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 297.0
HFD3_k127_1207969_1 PFAM Nucleotidyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000004134 237.0
HFD3_k127_1207969_2 epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000002846 81.0
HFD3_k127_121727_0 Aldehyde dehydrogenase family K00128 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009466 408.0
HFD3_k127_1219444_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004185 413.0
HFD3_k127_1219444_1 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 324.0
HFD3_k127_1219444_2 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000002913 268.0
HFD3_k127_1219444_3 peroxiredoxin activity - - - 0.00000000000000000001939 97.0
HFD3_k127_1238098_0 nucleic acid phosphodiester bond hydrolysis K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 430.0
HFD3_k127_1238098_1 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007304 290.0
HFD3_k127_1238098_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000003975 220.0
HFD3_k127_1238098_3 Diguanylate cyclase - - - 0.000000003588 59.0
HFD3_k127_1249144_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 495.0
HFD3_k127_1249144_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 414.0
HFD3_k127_1249144_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008069 319.0
HFD3_k127_1249144_3 Polysaccharide biosynthesis protein K01711,K15856 - 1.1.1.281,4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 297.0
HFD3_k127_1249144_4 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005402 286.0
HFD3_k127_1249144_5 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003014 270.0
HFD3_k127_1249144_6 - - - - 0.0000000000000000000000000000000000000000000000000000000008929 217.0
HFD3_k127_1260861_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K02887,K03628 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 3.782e-217 678.0
HFD3_k127_1260861_1 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000003331 131.0
HFD3_k127_1260861_2 LytR cell envelope-related transcriptional attenuator - - - 0.0000000000000002236 87.0
HFD3_k127_12828_0 glutamate decarboxylase activity K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 574.0
HFD3_k127_12828_1 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000001267 100.0
HFD3_k127_1290461_0 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006448,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072344,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112,GO:2000113,GO:2001124,GO:2001125 - 0.0000000000000000000000000000000000000000000000000000000000000000000000002246 252.0
HFD3_k127_1290461_1 RNA-DNA hybrid ribonuclease activity K03471 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000002864 181.0
HFD3_k127_132206_0 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005014 548.0
HFD3_k127_132206_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 403.0
HFD3_k127_132206_2 Activator of Hsp90 ATPase 1 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 309.0
HFD3_k127_132206_3 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003366 247.0
HFD3_k127_132206_4 Methyltransferase K00587 - 2.1.1.100 0.000000000000000000000000000000000000000000000000000000001003 207.0
HFD3_k127_132206_5 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000003523 168.0
HFD3_k127_132206_6 Cupin domain - - - 0.00000000000000000000000001732 113.0
HFD3_k127_132206_7 Divergent 4Fe-4S mono-cluster - - - 0.000000000000000001933 87.0
HFD3_k127_1324540_0 extracellular matrix structural constituent - - - 0.00000000000000000000005056 107.0
HFD3_k127_1324540_1 Por secretion system C-terminal sorting domain-containing protein - - - 0.00000000000000007959 93.0
HFD3_k127_1324540_2 Belongs to the 5'-nucleotidase family K01081,K11751 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006213,GO:0006259,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007155,GO:0007159,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009164,GO:0009166,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019362,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0022610,GO:0031974,GO:0031981,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042578,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046135,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0051186,GO:0055086,GO:0070013,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:0072524,GO:0072527,GO:0072529,GO:0090304,GO:0098609,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.1.3.5,3.6.1.45 0.00000000126 70.0
HFD3_k127_1334942_0 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000001903 206.0
HFD3_k127_1334942_1 Bacterial regulatory proteins, tetR family K09017 - - 0.0000000000000000000000000001634 123.0
HFD3_k127_1334942_2 transcriptional regulator K09017 - - 0.00000000000009921 79.0
HFD3_k127_1339510_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004051 541.0
HFD3_k127_1339510_1 EamA-like transporter family - - - 0.00000000000000000000000000057 119.0
HFD3_k127_1339510_2 Protein of unknown function (DUF1569) - - - 0.000000000000007149 81.0
HFD3_k127_1346357_0 methyltransferase - - - 4.813e-273 897.0
HFD3_k127_1346357_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 578.0
HFD3_k127_1346357_2 Cell wall formation K00075 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000003056 252.0
HFD3_k127_1346357_3 cellulase activity - - - 0.000000000000000000000000000000000000000009926 177.0
HFD3_k127_1346357_4 Calcium ion binding. It is involved in the biological process described with cell adhesion K04659 GO:0000902,GO:0001501,GO:0001503,GO:0001932,GO:0001934,GO:0001936,GO:0001938,GO:0001968,GO:0002020,GO:0002682,GO:0002684,GO:0002685,GO:0002687,GO:0002688,GO:0002690,GO:0003416,GO:0003417,GO:0003674,GO:0005102,GO:0005178,GO:0005198,GO:0005201,GO:0005488,GO:0005496,GO:0005499,GO:0005509,GO:0005515,GO:0005518,GO:0005539,GO:0005575,GO:0005576,GO:0005604,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005912,GO:0005924,GO:0005927,GO:0006928,GO:0006950,GO:0007155,GO:0007160,GO:0007275,GO:0007399,GO:0007517,GO:0007610,GO:0008150,GO:0008201,GO:0008284,GO:0008289,GO:0009653,GO:0009790,GO:0009887,GO:0009888,GO:0009893,GO:0009987,GO:0010562,GO:0010604,GO:0010941,GO:0012505,GO:0014812,GO:0016043,GO:0016203,GO:0016477,GO:0016525,GO:0016528,GO:0016529,GO:0019220,GO:0019222,GO:0019842,GO:0019899,GO:0021700,GO:0022008,GO:0022603,GO:0022607,GO:0022610,GO:0030030,GO:0030054,GO:0030055,GO:0030154,GO:0030182,GO:0030198,GO:0030334,GO:0030335,GO:0030855,GO:0031012,GO:0031175,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0031589,GO:0031594,GO:0032101,GO:0032103,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032879,GO:0032989,GO:0032990,GO:0032991,GO:0033554,GO:0033555,GO:0033627,GO:0034103,GO:0034976,GO:0035265,GO:0035989,GO:0036094,GO:0040007,GO:0040011,GO:0040012,GO:0040017,GO:0042127,GO:0042325,GO:0042327,GO:0042981,GO:0043062,GO:0043066,GO:0043067,GO:0043069,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043236,GO:0043237,GO:0043394,GO:0043395,GO:0043931,GO:0043933,GO:0044085,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045202,GO:0045765,GO:0045937,GO:0046872,GO:0048265,GO:0048266,GO:0048468,GO:0048471,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048589,GO:0048646,GO:0048666,GO:0048699,GO:0048705,GO:0048731,GO:0048736,GO:0048799,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0050678,GO:0050679,GO:0050730,GO:0050731,GO:0050789,GO:0050793,GO:0050794,GO:0050839,GO:0050840,GO:0050896,GO:0050920,GO:0050921,GO:0051093,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051216,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051259,GO:0051260,GO:0051270,GO:0051272,GO:0051451,GO:0051674,GO:0051716,GO:0060173,GO:0060231,GO:0060255,GO:0060343,GO:0060346,GO:0060348,GO:0060349,GO:0060350,GO:0060351,GO:0060429,GO:0060538,GO:0060548,GO:0061053,GO:0061061,GO:0061383,GO:0061430,GO:0061448,GO:0062023,GO:0065003,GO:0065007,GO:0070161,GO:0070977,GO:0071603,GO:0071622,GO:0071624,GO:0071695,GO:0071840,GO:0080090,GO:0090022,GO:0090023,GO:0090136,GO:0097159,GO:0097367,GO:0098609,GO:0098868,GO:0120036,GO:0120039,GO:1901342,GO:1901343,GO:1901681,GO:1902622,GO:1902624,GO:2000026,GO:2000145,GO:2000147,GO:2000181 - 0.00000000000000002514 97.0
HFD3_k127_1369303_0 Lamin Tail Domain - - - 0.0000000000000000008049 99.0
HFD3_k127_1369303_1 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000009321 93.0
HFD3_k127_1369303_3 Chaperone - - - 0.0008318 51.0
HFD3_k127_1373340_0 Acetyl-CoA acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 394.0
HFD3_k127_1373340_1 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000004979 63.0
HFD3_k127_1373797_0 Beta-eliminating lyase K01667 - 4.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 500.0
HFD3_k127_1373797_1 Myo-inositol-1-phosphate synthase K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 390.0
HFD3_k127_1373797_2 PFAM Integral membrane protein TerC K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 351.0
HFD3_k127_1373797_3 L-asparaginase II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 328.0
HFD3_k127_1373797_4 PFAM PfkB domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001484 276.0
HFD3_k127_1373797_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000001552 180.0
HFD3_k127_1375091_0 short-chain dehydrogenase reductase SDR K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001919 277.0
HFD3_k127_1375091_1 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000001471 90.0
HFD3_k127_1399824_0 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000004212 188.0
HFD3_k127_1399824_1 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.00000000000000000000004473 106.0
HFD3_k127_1399824_2 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563,K13626 - - 0.00000000000000001178 86.0
HFD3_k127_1405040_0 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 392.0
HFD3_k127_1405040_1 TPR repeat-containing protein - - - 0.00005604 53.0
HFD3_k127_1437092_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 1.528e-234 735.0
HFD3_k127_1437092_1 - - - - 0.000000000000000000000000000000000000313 147.0
HFD3_k127_1447444_0 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000002647 236.0
HFD3_k127_1455336_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008976 496.0
HFD3_k127_1455336_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 340.0
HFD3_k127_1455336_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006143 266.0
HFD3_k127_1455336_3 COG1136 ABC-type antimicrobial peptide transport system ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000007313 203.0
HFD3_k127_1455336_4 Putative metal-binding motif - - - 0.000000000000000000000000000000000000000000000000000003195 202.0
HFD3_k127_1455336_5 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000005416 210.0
HFD3_k127_1455336_6 RNA recognition motif K14789 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0008150,GO:0019843,GO:0022613,GO:0030684,GO:0030686,GO:0032991,GO:0042254,GO:0042274,GO:0044085,GO:0071840,GO:0097159,GO:1901363,GO:1990904 - 0.000000000007779 66.0
HFD3_k127_1455336_7 Lactonase, 7-bladed beta-propeller K07004 - - 0.00000002517 65.0
HFD3_k127_1484900_0 PFAM Peptidase family M20 M25 M40 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 500.0
HFD3_k127_1484900_1 Subtilase family K13276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000605 476.0
HFD3_k127_1484900_2 Belongs to the UPF0145 family - - - 0.00000000000000000000000000000000000000002534 159.0
HFD3_k127_1484900_3 extracellular matrix structural constituent - - - 0.000000000000000000002024 111.0
HFD3_k127_1484900_4 PBS lyase K22221 - - 0.0000000001231 73.0
HFD3_k127_148848_0 PFAM HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003521 250.0
HFD3_k127_148848_1 methyltransferase - - - 0.000000000000000000000000003866 124.0
HFD3_k127_150554_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00282 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008533 297.0
HFD3_k127_150554_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000002224 194.0
HFD3_k127_150554_2 Protein of unknown function, DUF255 - - - 0.000005648 56.0
HFD3_k127_1550966_0 COGs COG1629 Outer membrane receptor protein mostly Fe transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 394.0
HFD3_k127_1550966_1 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation K03800 - 6.3.1.20 0.00000000000000000000000000000000000001608 156.0
HFD3_k127_1563923_0 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02372,K02535,K13599,K16363 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171 3.5.1.108,4.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004596 552.0
HFD3_k127_1563923_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009283 318.0
HFD3_k127_1563923_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000003463 164.0
HFD3_k127_1583722_0 UPF0210 protein K09157 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 499.0
HFD3_k127_1583722_1 - - - - 0.000000000000000000000004943 110.0
HFD3_k127_1583722_2 STAS domain K04749 - - 0.000000000000003178 79.0
HFD3_k127_1605617_0 Peptidase M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003364 276.0
HFD3_k127_1605617_1 Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation K07130 - 3.5.1.9 0.0000000000000000000000000000000000000000000003829 174.0
HFD3_k127_1605617_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000001042 111.0
HFD3_k127_1605617_3 Helix-hairpin-helix motif K02237 - - 0.000000000004189 71.0
HFD3_k127_1605617_4 Conserved hypothetical protein 95 - - - 0.0000001449 55.0
HFD3_k127_1614689_0 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 310.0
HFD3_k127_1614689_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000007607 81.0
HFD3_k127_1618775_0 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009722 244.0
HFD3_k127_1618775_1 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000003056 178.0
HFD3_k127_1618775_2 Belongs to the LarC family K09121 - 4.99.1.12 0.00000007353 62.0
HFD3_k127_1623418_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000536 494.0
HFD3_k127_1623418_1 Carbon-nitrogen hydrolase K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001034 282.0
HFD3_k127_1623418_2 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000005042 188.0
HFD3_k127_1623418_3 Glycosyltransferase like family 2 K07011 - - 0.0000000000000000000000000000000001209 149.0
HFD3_k127_1623418_4 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000005181 147.0
HFD3_k127_1623418_5 Two component regulator propeller - - - 0.00000000000000000000000000000023 143.0
HFD3_k127_1623418_6 Nitrous oxide-stimulated promoter - - - 0.0000000000000000000000000001406 126.0
HFD3_k127_1623418_7 MraZ protein, putative antitoxin-like K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.000000000000001666 79.0
HFD3_k127_162435_0 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 2.165e-230 734.0
HFD3_k127_162435_1 metalloenzyme domain protein K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 392.0
HFD3_k127_162435_2 photosynthesis K02656 - - 0.0000002637 54.0
HFD3_k127_165062_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 540.0
HFD3_k127_165062_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 469.0
HFD3_k127_165062_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000004661 258.0
HFD3_k127_165062_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000001122 179.0
HFD3_k127_165062_4 Thioredoxin-like [2Fe-2S] ferredoxin K00334,K00335 - 1.6.5.3 0.000000000000000000000000000000000000003236 152.0
HFD3_k127_1662020_0 Dehydrogenase K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 475.0
HFD3_k127_1662020_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001036 263.0
HFD3_k127_1662020_2 Cobalamin B12-binding K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000007255 198.0
HFD3_k127_1662020_3 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000002678 190.0
HFD3_k127_1662020_4 ASPIC and UnbV - - - 0.0000000000000000000000000000007437 132.0
HFD3_k127_1662020_5 guanyl-nucleotide exchange factor activity - - - 0.000000000000000000001705 104.0
HFD3_k127_1662020_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000001945 55.0
HFD3_k127_1678760_0 Two component regulator propeller K19693 - - 0.000000000000000000000000000000000000000000000000000000000000000000000918 257.0
HFD3_k127_1678760_1 - - - - 0.00000000000000000000008952 98.0
HFD3_k127_1678760_2 PFAM YbbR family protein - - - 0.0003108 48.0
HFD3_k127_1691698_0 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K01768,K07315 - 3.1.3.3,4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 398.0
HFD3_k127_1704542_0 Pyruvate:ferredoxin oxidoreductase core domain II K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 437.0
HFD3_k127_1704542_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175,K00177,K00187 - 1.2.7.11,1.2.7.3,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002632 283.0
HFD3_k127_1704542_2 4Fe-4S dicluster domain K16950 - - 0.00000000000000000000000007076 113.0
HFD3_k127_1704542_3 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.0000000000000000003806 91.0
HFD3_k127_1725145_0 phosphoserine phosphatase activity K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004928 364.0
HFD3_k127_1725145_1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000000000000000000000000000000002135 195.0
HFD3_k127_1725145_2 EamA-like transporter family K07790 - - 0.000000000000000000000000000000000000000000002326 176.0
HFD3_k127_1725145_3 EamA-like transporter family K07790 - - 0.000005825 50.0
HFD3_k127_1740966_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 5.685e-279 874.0
HFD3_k127_1740966_1 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 6.516e-259 818.0
HFD3_k127_1740966_2 Phosphoribosyl transferase domain K00760 GO:0000287,GO:0003674,GO:0003824,GO:0004422,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006166,GO:0006177,GO:0006188,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032261,GO:0032263,GO:0032264,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043167,GO:0043169,GO:0043173,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.8 0.000000000000000000000000000000000000000000000003864 178.0
HFD3_k127_1740966_3 TIGRFAM addiction module antidote protein, HigA family K21498 - - 0.00000000000000000000000000000000000000002883 158.0
HFD3_k127_1740966_4 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000002659 150.0
HFD3_k127_1740966_5 - - - - 0.000000000000000000000000000000005286 134.0
HFD3_k127_1740966_6 long-chain fatty acid transport protein - - - 0.00000000000000000000004612 108.0
HFD3_k127_1740966_7 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.000000009354 59.0
HFD3_k127_1757001_0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000001483 237.0
HFD3_k127_1757001_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000007708 230.0
HFD3_k127_1757001_2 Protein of unknown function (DUF2723) - - - 0.0000000000000000000000000000000000000000000000000000000007852 222.0
HFD3_k127_1757001_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000001065 197.0
HFD3_k127_1757001_4 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363,GO:1901576 - 0.00000000000000000000000000000000000000000000000001234 184.0
HFD3_k127_1757001_5 PAP2 superfamily - - - 0.000000000000000000000000000000693 138.0
HFD3_k127_1757001_6 Pas domain - - - 0.00000000000000001378 89.0
HFD3_k127_1757001_7 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000005742 55.0
HFD3_k127_1768602_0 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000362 375.0
HFD3_k127_1768602_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008378 294.0
HFD3_k127_1768602_2 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000002135 185.0
HFD3_k127_1768602_3 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000002037 128.0
HFD3_k127_1775432_0 sh3 domain protein K01448 - 3.5.1.28 0.000000000000000000000000000000000001171 147.0
HFD3_k127_1775432_1 sh3 domain protein K01448 - 3.5.1.28 0.0000000000000000000000006964 111.0
HFD3_k127_1775432_2 Belongs to the HesB IscA family K13628,K15724 - - 0.000008596 49.0
HFD3_k127_1776658_0 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009417 283.0
HFD3_k127_1776658_1 UDP binding domain K02474,K13015 - 1.1.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000504 273.0
HFD3_k127_1776658_2 PFAM metallophosphoesterase K03269 - 3.6.1.54 0.00000000000000000000000000000002419 133.0
HFD3_k127_1780531_0 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008478 511.0
HFD3_k127_1780531_1 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 453.0
HFD3_k127_1780531_2 Proline racemase K12658 - 5.1.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 397.0
HFD3_k127_1780531_3 - - - - 0.00000000000000000000000000000000000000000000001059 175.0
HFD3_k127_1780531_4 FAD dependent oxidoreductase K00285 - 1.4.5.1 0.00000000000000000000000000000002401 131.0
HFD3_k127_1780531_5 SnoaL-like domain - - - 0.0004013 49.0
HFD3_k127_1786139_0 - - - - 0.000000000000000000000000000000000000000000000000000000007774 219.0
HFD3_k127_1833733_0 Belongs to the GSP D family K02280 - - 0.000000000000000000000000000000000000000000000000003049 197.0
HFD3_k127_1833733_1 Flp pilus polar localization response receiver ATPase TadZ, FlhG domain-containing K02282 - - 0.00000000000000000000000000000000000000000000000003311 194.0
HFD3_k127_1833733_2 Putative Flp pilus-assembly TadE/G-like - - - 0.0000000000000000000000000000000000000000009164 172.0
HFD3_k127_184315_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02022,K16922,K20345 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 376.0
HFD3_k127_184315_1 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000597 219.0
HFD3_k127_184315_2 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.0000004888 58.0
HFD3_k127_1875959_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 317.0
HFD3_k127_1875959_1 PFAM Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000002755 117.0
HFD3_k127_1875959_2 NifU-like domain - - - 0.0000000000000000003478 89.0
HFD3_k127_1875959_3 CAAX protease self-immunity K07052 - - 0.000000000000004311 85.0
HFD3_k127_1875959_4 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000003878 79.0
HFD3_k127_1886282_0 Propeptide_C25 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 444.0
HFD3_k127_1886482_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 523.0
HFD3_k127_1904206_0 Thiamine biosynthesis protein (ThiI) - - - 0.000000000000000000000000007638 115.0
HFD3_k127_1904206_1 gluconolactonase activity K01406,K14274,K20276,K21449 - 3.4.24.40 0.000000000000022 85.0
HFD3_k127_1904206_2 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) K12116 - - 0.0000007341 62.0
HFD3_k127_1904206_3 Chitinase C K01183,K21606 - 3.2.1.14,3.2.1.202 0.0004432 53.0
HFD3_k127_1916111_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 342.0
HFD3_k127_1916111_1 shikimate 3-dehydrogenase (NADP+) activity K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000004333 172.0
HFD3_k127_1916111_2 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000002343 117.0
HFD3_k127_1916111_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00002308 50.0
HFD3_k127_1962291_0 Trypsin K04771,K04772 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 463.0
HFD3_k127_1962291_1 PFAM peptidase M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 323.0
HFD3_k127_1962291_2 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000004359 141.0
HFD3_k127_1962291_3 long-chain fatty acid transporting porin activity - - - 0.00000000000000007453 94.0
HFD3_k127_1962291_4 Trypsin - - - 0.00000002436 61.0
HFD3_k127_1962291_5 Exopolysaccharide biosynthesis protein YbjH - - - 0.0000009454 51.0
HFD3_k127_1962291_6 Tetratricopeptide TPR_2 repeat protein - - - 0.00008696 53.0
HFD3_k127_1963153_0 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.000000000000000000000000000000000000000000175 174.0
HFD3_k127_1963153_1 TRAP transporter T-component - - - 0.00000000000000000000000000000171 132.0
HFD3_k127_1963153_2 Uncharacterized ACR, COG1430 K09005 - - 0.000000000001827 76.0
HFD3_k127_1963153_3 Efflux ABC transporter, permease protein K02004 - - 0.000003987 58.0
HFD3_k127_196636_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0 1097.0
HFD3_k127_196636_1 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000006399 139.0
HFD3_k127_196636_2 COG2143 Thioredoxin-related protein - - - 0.00000000000000000001928 98.0
HFD3_k127_1973961_0 Bacterial protein of unknown function (DUF885) - - - 4.073e-195 625.0
HFD3_k127_1973961_1 oligoendopeptidase F K08602 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 407.0
HFD3_k127_1973961_2 Thrombospondin type 3 repeat - - - 0.000000000000000000000000000000000000000000000001918 197.0
HFD3_k127_201387_0 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005611 394.0
HFD3_k127_201387_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000001577 238.0
HFD3_k127_2026114_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1108.0
HFD3_k127_2026114_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043,K13797 GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 3.822e-220 691.0
HFD3_k127_2031739_0 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 582.0
HFD3_k127_2031739_1 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000000000000000000000000000000003611 191.0
HFD3_k127_2031739_2 PFAM peptidase - - - 0.000000000000000000000000000000004619 139.0
HFD3_k127_2031739_3 Trypsin K04771 - 3.4.21.107 0.000000002263 64.0
HFD3_k127_205102_0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 311.0
HFD3_k127_2074534_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 437.0
HFD3_k127_2074534_1 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000002524 211.0
HFD3_k127_2074534_2 Domain of Unknown Function (DUF1259) - - - 0.000000000000000000000000000000000000003223 147.0
HFD3_k127_2080331_0 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744,K09774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008954 404.0
HFD3_k127_2081832_0 - - - - 0.000000000000000000000000000000000000001745 148.0
HFD3_k127_2081832_1 - - - - 0.0000000000000000000000005625 107.0
HFD3_k127_2081832_2 Glycosyl transferases group 1 - - - 0.000000000000000000003073 105.0
HFD3_k127_2081832_3 - - - - 0.000000000000000005858 83.0
HFD3_k127_2082704_0 modulates the activities of several proteins which are inactive in their K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003767 268.0
HFD3_k127_2082704_1 - - - - 0.00000000007224 71.0
HFD3_k127_2082704_2 Tetratricopeptide repeat - - - 0.00000002198 61.0
HFD3_k127_2082704_3 Diacylglycerol kinase catalytic domain (presumed) - - - 0.00000003559 65.0
HFD3_k127_2091501_0 Polysaccharide biosynthesis protein CapD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 415.0
HFD3_k127_2091501_1 Tetratricopeptide repeat - - - 0.0000000002371 73.0
HFD3_k127_2099741_0 belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000001409 160.0
HFD3_k127_2099741_1 D,D-heptose 1,7-bisphosphate phosphatase K02841,K02843,K02849,K03271,K03272,K03273 - 2.7.1.167,2.7.7.70,3.1.3.82,3.1.3.83,5.3.1.28 0.00000000000000000000000000000004977 138.0
HFD3_k127_2099741_2 CoA binding domain K06929 - - 0.000000000000000000000000005157 115.0
HFD3_k127_2099741_3 Belongs to the heme-copper respiratory oxidase family - - - 0.00000000000000000000005279 108.0
HFD3_k127_2099741_4 - - - - 0.000000000132 74.0
HFD3_k127_2099741_5 AsmA-like C-terminal region - - - 0.000000001369 70.0
HFD3_k127_2115107_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 341.0
HFD3_k127_2115107_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000001726 260.0
HFD3_k127_2115107_2 Deoxynucleoside kinase K15518 - 2.7.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000002223 246.0
HFD3_k127_2115107_3 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000001611 248.0
HFD3_k127_2115107_4 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000000002347 145.0
HFD3_k127_2115107_5 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000000000000000000000000000007988 139.0
HFD3_k127_2115107_6 Class ii aldolase K01628,K11216 - 2.7.1.189,4.1.2.17 0.000000000000000000000000001082 116.0
HFD3_k127_2115107_7 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000000002229 121.0
HFD3_k127_2115107_8 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000002885 58.0
HFD3_k127_2116055_0 MotA/TolQ/ExbB proton channel family K03561,K03562 - - 0.0000000000000000000000000000000000000000000006724 175.0
HFD3_k127_2116055_1 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.000000000000000000000000000003966 124.0
HFD3_k127_2116055_2 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019904,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701 - 0.0000000001748 70.0
HFD3_k127_2116055_3 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00001071 56.0
HFD3_k127_2134773_0 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806,K12503 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006475 335.0
HFD3_k127_2134773_1 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000002013 218.0
HFD3_k127_2134773_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000007485 111.0
HFD3_k127_2134773_3 Belongs to the CDS family K00981 - 2.7.7.41 0.000144 50.0
HFD3_k127_2145708_0 Protein of unknown function, DUF255 K04084,K06888 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 625.0
HFD3_k127_2145708_1 peroxiredoxin activity - - - 0.0000000000000000000000000000000000000000000006033 171.0
HFD3_k127_2160075_0 PFAM tRNA synthetases class I (E and Q), catalytic domain K01886 - 6.1.1.18 2.668e-274 854.0
HFD3_k127_2160075_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 532.0
HFD3_k127_2167263_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006488 528.0
HFD3_k127_2171907_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 1.207e-215 676.0
HFD3_k127_2171907_1 Cys Met metabolism K01739,K01758 - 2.5.1.48,4.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000001045 226.0
HFD3_k127_2171907_2 - - - - 0.000000000000000000000000000000739 126.0
HFD3_k127_2174769_0 Cys Met metabolism K01739,K01758 - 2.5.1.48,4.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000008053 255.0
HFD3_k127_2174769_1 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000002417 244.0
HFD3_k127_2179453_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 473.0
HFD3_k127_2179453_1 belongs to the aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006479 248.0
HFD3_k127_2179453_2 SMART Integrin alpha beta-propellor repeat protein - - - 0.00000000000000000000000000000000000000000008788 181.0
HFD3_k127_2216093_0 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007239 372.0
HFD3_k127_223688_0 Serine carboxypeptidase - - - 3.453e-196 629.0
HFD3_k127_223688_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006512 425.0
HFD3_k127_223688_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000301 286.0
HFD3_k127_223688_3 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000001543 225.0
HFD3_k127_223688_4 Sigma-54 interaction domain K10126 - - 0.000000000000000000000007441 117.0
HFD3_k127_223688_5 Protein of unknown function, DUF255 K06888 - - 0.000000004605 60.0
HFD3_k127_2240936_0 PFAM polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000007502 153.0
HFD3_k127_2240936_1 PFAM Peptidase M16 inactive domain K07263 - - 0.0000000000000000000000905 108.0
HFD3_k127_2247022_0 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 313.0
HFD3_k127_2247022_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006711 249.0
HFD3_k127_2247022_2 - - - - 0.000000000000000000000000000000000000000000000000000000000003958 220.0
HFD3_k127_2247022_3 - - - - 0.0000000000000000001053 93.0
HFD3_k127_2247022_4 - - - - 0.00000000003078 64.0
HFD3_k127_2249425_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006546,GO:0006563,GO:0006565,GO:0006730,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009070,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019264,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042133,GO:0042135,GO:0042136,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 559.0
HFD3_k127_2249425_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 497.0
HFD3_k127_2249425_10 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000003305 115.0
HFD3_k127_2249425_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 447.0
HFD3_k127_2249425_3 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 420.0
HFD3_k127_2249425_4 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007234 365.0
HFD3_k127_2249425_5 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005796 358.0
HFD3_k127_2249425_6 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007315 320.0
HFD3_k127_2249425_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009314,GO:0009628,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000000000001188 237.0
HFD3_k127_2249425_8 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000001101 186.0
HFD3_k127_2249425_9 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000002316 160.0
HFD3_k127_2250698_0 Ftsk_gamma K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 413.0
HFD3_k127_2272374_0 - - - - 3.033e-264 848.0
HFD3_k127_2272374_1 Predicted Permease Membrane Region K07085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 465.0
HFD3_k127_2272374_2 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D K01424,K05597 GO:0003674,GO:0003824,GO:0004067,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006530,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009066,GO:0009068,GO:0009987,GO:0016043,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0022607,GO:0030288,GO:0030313,GO:0031975,GO:0032787,GO:0034641,GO:0042597,GO:0042802,GO:0043436,GO:0043603,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:0072329,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.1,3.5.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008254 411.0
HFD3_k127_2272374_3 CarboxypepD_reg-like domain K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 407.0
HFD3_k127_2272374_4 anaerobic c4-dicarboxylate K07791,K07792 - - 0.000000000000000000000000000000000002065 141.0
HFD3_k127_2293408_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 554.0
HFD3_k127_2293408_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 471.0
HFD3_k127_2293408_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 383.0
HFD3_k127_2293408_3 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis K06208 - 5.4.99.5 0.000000000000000000000000000000001319 137.0
HFD3_k127_2293408_4 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000004142 136.0
HFD3_k127_2308039_0 Belongs to the short-chain dehydrogenases reductases (SDR) family K05886 - 1.1.1.276 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 296.0
HFD3_k127_2314708_0 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 542.0
HFD3_k127_2314708_1 N-acetylglucosaminylinositol deacetylase activity K22135 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 287.0
HFD3_k127_2314708_2 benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.00000000000000000000000000000000000000000000002551 185.0
HFD3_k127_2314708_4 Methyltransferase domain - - - 0.00000003003 63.0
HFD3_k127_2330228_0 lysine 2,3-aminomutase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 432.0
HFD3_k127_2330228_1 Belongs to the SIS family. GutQ KpsF subfamily K01627,K03281,K06041 - 2.5.1.55,5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 334.0
HFD3_k127_2330228_2 PFAM DAHP synthetase I KDSA K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007179 280.0
HFD3_k127_2330228_3 Enoyl-(Acyl carrier protein) reductase K10780 - 1.3.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000155 250.0
HFD3_k127_2330228_4 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000001014 246.0
HFD3_k127_2330228_5 TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.0000000000000000000000000000004036 130.0
HFD3_k127_2344716_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 505.0
HFD3_k127_2344716_1 4Fe-4S binding domain K08358 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 318.0
HFD3_k127_2344716_2 Amidinotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 302.0
HFD3_k127_2344716_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K04013,K15876 - - 0.0000000000000000000000000000000000000000000000000000000000007115 218.0
HFD3_k127_2344716_4 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000009016 113.0
HFD3_k127_2351689_0 FlgD Ig-like domain K14194,K19668 - 3.2.1.91 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008106 328.0
HFD3_k127_2351689_1 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 295.0
HFD3_k127_2351689_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000005451 186.0
HFD3_k127_2351689_3 Metallo-beta-lactamase superfamily K02238 - - 0.00000000000000000000000000000000000000644 167.0
HFD3_k127_2369400_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 446.0
HFD3_k127_2369400_1 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004547 371.0
HFD3_k127_2369400_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000003263 147.0
HFD3_k127_2369400_3 Polymer-forming cytoskeletal - - - 0.0001351 46.0
HFD3_k127_2378604_0 Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000003058 222.0
HFD3_k127_2378604_1 carbohydrate transport K02027 - - 0.000000000000000000008728 104.0
HFD3_k127_2381339_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 475.0
HFD3_k127_2381339_1 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000007189 237.0
HFD3_k127_2381339_2 PASTA domain protein K01921,K08884,K12132 - 2.7.11.1,6.3.2.4 0.0005285 46.0
HFD3_k127_2383283_1 Transposase DDE domain - - - 0.0000000000685 72.0
HFD3_k127_2383283_2 PFAM Transposase, IS4-like - - - 0.000449 46.0
HFD3_k127_2399900_0 Aldehyde dehydrogenase family K04072,K13922 - 1.1.1.1,1.2.1.10,1.2.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 462.0
HFD3_k127_2399900_1 calcium- and calmodulin-responsive adenylate cyclase activity K01406,K07004 - 3.4.24.40 0.0000000000000000000000000000000000000000000000000000000000000000009902 239.0
HFD3_k127_2399900_2 May be involved in the formation of a specific microcompartment in the cell in which the metabolism of potentially toxic by-products takes place K04027 GO:0003674,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0031469,GO:0031471,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000003854 145.0
HFD3_k127_2433418_0 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 319.0
HFD3_k127_2433418_2 Belongs to the peptidase S8 family - - - 0.0000000001653 75.0
HFD3_k127_2451851_0 Cytochrome C assembly protein K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.000000000000000000000000000000000000000000000000209 185.0
HFD3_k127_2451851_1 CcmB protein K02193,K02194 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.41 0.000000000000000000000000000000000000000000000001403 182.0
HFD3_k127_2451851_2 PFAM ABC transporter related K02193 - 3.6.3.41 0.000000000000000007943 86.0
HFD3_k127_2460354_0 Isocitrate/isopropylmalate dehydrogenase K00031 GO:0003674,GO:0003824,GO:0003862,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022900,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 580.0
HFD3_k127_2460354_1 NYN domain - - - 0.000000000000000000000000000000000000000000000000000009523 196.0
HFD3_k127_2460354_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000004296 163.0
HFD3_k127_2472537_0 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002253 259.0
HFD3_k127_2472537_1 Protein of unknown function, DUF255 K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000873 261.0
HFD3_k127_2472537_2 peptidase S9 prolyl oligopeptidase active site K01303 - 3.4.19.1 0.000000000000000000000000000000000000000000000000000000000000001489 225.0
HFD3_k127_2472537_3 Thioesterase superfamily - - - 0.000000000000000000000000000000000000004636 149.0
HFD3_k127_2472537_4 exo-alpha-(2->6)-sialidase activity - - - 0.00000006405 61.0
HFD3_k127_2486192_0 Bacterial Ig-like domain - - - 0.000000000000000000000000002902 127.0
HFD3_k127_2486192_1 Tetratricopeptide repeat - - - 0.000000000000000002317 98.0
HFD3_k127_2486192_2 Protein conserved in bacteria - - - 0.0006843 54.0
HFD3_k127_2491904_0 Flagellar protein export ATPase FliI K02412 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 470.0
HFD3_k127_2491904_1 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02410 GO:0001539,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006928,GO:0006935,GO:0006996,GO:0008150,GO:0009288,GO:0009425,GO:0009605,GO:0009987,GO:0016020,GO:0016043,GO:0022607,GO:0030030,GO:0030031,GO:0040011,GO:0042221,GO:0042330,GO:0042802,GO:0042803,GO:0042995,GO:0043226,GO:0043228,GO:0044085,GO:0044403,GO:0044419,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0044780,GO:0044781,GO:0046982,GO:0046983,GO:0048870,GO:0050896,GO:0051179,GO:0051674,GO:0051701,GO:0051704,GO:0052116,GO:0052126,GO:0052127,GO:0052143,GO:0052192,GO:0052195,GO:0052216,GO:0052243,GO:0070925,GO:0071840,GO:0071944,GO:0071973,GO:0071978,GO:0097588 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 327.0
HFD3_k127_2491904_2 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02416 - - 0.0000000000000000000000000000000000000000000000000000000000000003329 232.0
HFD3_k127_2491904_3 The M ring may be actively involved in energy transduction K02409 - - 0.0000000000000000005825 93.0
HFD3_k127_2491904_4 PFAM flagellar FlbD family protein K02385 - - 0.0000000000000006063 81.0
HFD3_k127_2491904_5 flagellar assembly protein FliH K02411 - - 0.00001312 55.0
HFD3_k127_249504_0 ERAP1-like C-terminal domain K01256,K01263 - 3.4.11.14,3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005016 352.0
HFD3_k127_249504_1 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000006568 162.0
HFD3_k127_249504_2 DNA-templated transcription, initiation - - - 0.00000000000000000000000000000000000000608 158.0
HFD3_k127_2498801_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009509 281.0
HFD3_k127_2498801_1 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004987 263.0
HFD3_k127_2498801_2 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000005706 219.0
HFD3_k127_2498801_3 - - - - 0.00000000000000000000000000000000000007523 148.0
HFD3_k127_2498801_4 sequence-specific DNA binding K01247,K10778,K13529,K13530,K15051 - 2.1.1.63,3.2.2.21 0.000000000000000000000000000000000001831 144.0
HFD3_k127_2498801_6 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000002382 89.0
HFD3_k127_2498801_7 cellulase activity - - - 0.0000000000000000573 95.0
HFD3_k127_2498801_8 Belongs to the peptidase S8 family - - - 0.00000000000002004 87.0
HFD3_k127_2511673_0 Histidine kinase K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000114 191.0
HFD3_k127_2511673_1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K11384 - - 0.0007844 42.0
HFD3_k127_2514365_0 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 355.0
HFD3_k127_2514365_1 Transporter associated domain K03699,K06189 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000005024 251.0
HFD3_k127_2514365_2 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000281 183.0
HFD3_k127_2514365_3 Psort location Cytoplasmic, score 8.96 K02806 - - 0.0000000000000000000000000000004299 134.0
HFD3_k127_2514365_4 Peptidase family S49 K04773 - - 0.0000000000000003995 91.0
HFD3_k127_2514365_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000001761 74.0
HFD3_k127_2514516_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.369e-199 627.0
HFD3_k127_2514516_1 Belongs to the glycosyl hydrolase 57 family - - - 0.0000000000000000000000000000000000000000000000003471 177.0
HFD3_k127_2520926_0 LemA family K03744 - - 0.00000000000000000000000000000005485 139.0
HFD3_k127_2520926_1 Belongs to the peptidase S8 family - - - 0.0000000009315 62.0
HFD3_k127_2521710_0 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000004739 108.0
HFD3_k127_2521710_1 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000005093 85.0
HFD3_k127_255009_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051258,GO:0051301,GO:0065003,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 438.0
HFD3_k127_255009_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006136 374.0
HFD3_k127_255009_2 Mur ligase family, catalytic domain K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000002548 215.0
HFD3_k127_255009_3 Essential cell division protein K03589,K06438 - - 0.0000001625 62.0
HFD3_k127_256105_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007551 576.0
HFD3_k127_256105_1 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.00000000000000000000000000000000000000000000000001867 181.0
HFD3_k127_256105_2 nucleotide catabolic process K05996 - 3.4.17.18 0.0000000000000000000006065 108.0
HFD3_k127_256105_3 NAD(P)+ transhydrogenase (AB-specific) activity K00324 - 1.6.1.2 0.0000000000000000000006255 102.0
HFD3_k127_2572002_0 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000006632 250.0
HFD3_k127_2572002_1 synthase K12434 - - 0.00004913 47.0
HFD3_k127_2606755_0 alpha amylase, catalytic region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007839 593.0
HFD3_k127_2606755_1 peptide catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 380.0
HFD3_k127_2606755_2 PFAM Glycosyl transferases group 1 K13057 - 2.4.1.245 0.000000000000000000000000000000000001006 140.0
HFD3_k127_2611273_0 PFAM peptidase M6, immune inhibitor A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000655 328.0
HFD3_k127_2611273_2 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000001579 211.0
HFD3_k127_2611273_3 signal transduction HD GYP protein - - - 0.000000000000000000000000000000000000000000002035 177.0
HFD3_k127_2611273_4 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000002444 94.0
HFD3_k127_2611273_5 Capsule assembly protein Wzi - - - 0.000000000000001312 86.0
HFD3_k127_2636133_0 Belongs to the RtcB family K14415 - 6.5.1.3 1.98e-197 627.0
HFD3_k127_2636133_1 Oligopeptidase F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 542.0
HFD3_k127_2636133_2 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000000003342 108.0
HFD3_k127_2636133_3 FlgD Ig-like domain - - - 0.0000000000000000000005892 111.0
HFD3_k127_2636133_4 Protein of unknown function (DUF1573) - - - 0.0000000000000005321 84.0
HFD3_k127_2654312_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 6.185e-198 633.0
HFD3_k127_2654312_1 - - - - 0.000000000000000000000009243 104.0
HFD3_k127_266568_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006217 327.0
HFD3_k127_266568_1 PFAM Glycosyl transferase family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 305.0
HFD3_k127_2675086_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 3.85e-243 762.0
HFD3_k127_2675086_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000001078 91.0
HFD3_k127_2686502_0 Aminotransferase class-III K00823,K03918,K20428 - 2.6.1.19,2.6.1.33,2.6.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 579.0
HFD3_k127_2686502_1 Aspartate ammonia-lyase K01679,K01744 - 4.2.1.2,4.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003812 392.0
HFD3_k127_2686502_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000005308 198.0
HFD3_k127_2686502_3 4'-phosphopantetheinyl transferase superfamily K00997 - 2.7.8.7 0.00000000000000000002499 98.0
HFD3_k127_2686502_4 - - - - 0.0000000003943 71.0
HFD3_k127_2686502_5 protocatechuate 3,4-dioxygenase activity K00449 - 1.13.11.3 0.00000002713 57.0
HFD3_k127_2694887_0 Pilus assembly protein PilX - - - 0.0000000000000000001663 102.0
HFD3_k127_2695788_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 512.0
HFD3_k127_2695788_1 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006793 293.0
HFD3_k127_2695788_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000007073 229.0
HFD3_k127_2695788_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000002556 121.0
HFD3_k127_2719898_0 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009446 539.0
HFD3_k127_2719898_1 Belongs to the UPF0219 family K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 402.0
HFD3_k127_2719898_2 PFAM Thiolase K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 290.0
HFD3_k127_2719898_3 Glyoxalase-like domain K05606 - 5.1.99.1 0.0000000000000000000000000000004192 127.0
HFD3_k127_2722940_1 Hep Hag repeat protein - - - 0.0000000000005166 82.0
HFD3_k127_2722940_2 Polysulphide reductase, NrfD - - - 0.00000343 53.0
HFD3_k127_2727445_0 Secretin and TonB N terminus short domain K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003887 333.0
HFD3_k127_2727445_1 Type IV pilus assembly protein PilM; K02662 - - 0.00000000000000000000000000000000000000000005114 161.0
HFD3_k127_2727445_3 PFAM Fimbrial assembly family protein K02663 - - 0.000000000000000000000000000000001616 140.0
HFD3_k127_2727445_4 Pilus assembly protein PilO K02664 - - 0.000003616 57.0
HFD3_k127_2752081_0 Glycosyl transferase family 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002771 258.0
HFD3_k127_2752081_1 Glycosyl transferases group 1 K13668 - 2.4.1.346 0.00000000000000000000000000001705 132.0
HFD3_k127_2764975_0 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 522.0
HFD3_k127_2764975_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 - 3.1.11.5 0.00000000000000000000000000000000000000000000000000000000006498 222.0
HFD3_k127_2764975_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075,K15780 - 2.4.2.8,6.3.4.19 0.0000000000000000000005025 99.0
HFD3_k127_2769248_0 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000002156 210.0
HFD3_k127_2769248_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000001503 157.0
HFD3_k127_2769248_2 metallopeptidase activity K06889 - - 0.0000000000000000000000000000000000000002178 166.0
HFD3_k127_2769248_3 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000447 78.0
HFD3_k127_2769248_4 intracellular protein transport K05989 - 3.2.1.40 0.00000000003215 76.0
HFD3_k127_2770457_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 359.0
HFD3_k127_2770457_1 peptidase - - - 0.0006192 51.0
HFD3_k127_2795260_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007513 548.0
HFD3_k127_2795260_1 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 462.0
HFD3_k127_2795260_2 Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000271 254.0
HFD3_k127_2795260_3 FlgD Ig-like domain - - - 0.00000000000000000000000000000000000000000000000000000002105 226.0
HFD3_k127_2796371_0 PFAM ATP-binding region, ATPase domain protein K07709 - 2.7.13.3 0.000000000000000000000000000000000003089 155.0
HFD3_k127_2796371_1 Probable zinc-ribbon domain - - - 0.000000003272 62.0
HFD3_k127_2811290_0 Penicillin-Binding Protein C-terminus Family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004619 407.0
HFD3_k127_2821092_0 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007211 341.0
HFD3_k127_2821092_1 PFAM Mandelate racemase muconate lactonizing protein K19802 - 5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000004062 252.0
HFD3_k127_2821092_2 - - - - 0.0000000000000000000000000000001433 141.0
HFD3_k127_2824388_0 OmpA family K03286 - - 0.0000000000000000000000000000000000000000007907 176.0
HFD3_k127_2824388_1 Alpha-L-fucosidase K01206 - 3.2.1.51 0.000000000000000000000000000002628 136.0
HFD3_k127_2824388_2 Glycosyl hydrolase family 38 C-terminal domain protein K01191 - 3.2.1.24 0.0000000000000000001271 103.0
HFD3_k127_283448_0 TIGRFAM polysaccharide deactylase family protein, PEP-CTERM locus subfamily - - - 0.00000000000000000000000000000000000000000000000001038 197.0
HFD3_k127_283448_1 dolichyl monophosphate biosynthetic process K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000402 162.0
HFD3_k127_283448_2 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000005143 124.0
HFD3_k127_283448_3 Succinoglycan biosynthesis protein exoa - - - 0.00000000000000000004985 94.0
HFD3_k127_283448_4 Cold shock protein domain K03704 - - 0.00000000000000000005934 90.0
HFD3_k127_283448_5 isomerase K03770 - 5.2.1.8 0.000001543 59.0
HFD3_k127_2842315_0 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006015 453.0
HFD3_k127_2850626_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 GO:0003674,GO:0003824,GO:0004812,GO:0004815,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006422,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.12 9.825e-225 713.0
HFD3_k127_2850626_1 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006218 398.0
HFD3_k127_2850626_2 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02481,K07714 - - 0.00000000000000000000000000000000000000000000000000003214 194.0
HFD3_k127_2850626_3 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000006027 85.0
HFD3_k127_2850626_4 VanZ like family - - - 0.000000000001931 72.0
HFD3_k127_2854716_0 Ribonuclease E/G family K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007023 450.0
HFD3_k127_2854716_1 Peptidylprolyl isomerase K01802,K03769,K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007777 299.0
HFD3_k127_2854716_2 Band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001448 261.0
HFD3_k127_2854716_3 (Rhomboid) family K07059 - - 0.00000000000000000000000000000000000000000000000000000000000000006212 242.0
HFD3_k127_2854716_4 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000001286 208.0
HFD3_k127_2854716_5 - - - - 0.00000001946 57.0
HFD3_k127_2859202_0 methyltransferase - - - 0.00000000000000000000000000000000000000000000002939 179.0
HFD3_k127_2859202_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000002155 165.0
HFD3_k127_2859202_2 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000008277 157.0
HFD3_k127_2865844_0 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000008245 115.0
HFD3_k127_2866802_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 1.291e-197 632.0
HFD3_k127_2866802_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 303.0
HFD3_k127_2866802_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000001052 227.0
HFD3_k127_2866802_3 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.0000000000000000000000000000000000000001043 158.0
HFD3_k127_2866802_4 Peptidase family M50 K06402 - - 0.0000000000000000000000000000000000001807 148.0
HFD3_k127_2866873_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 439.0
HFD3_k127_2866873_1 C4-type zinc ribbon domain K07164,K22391 - 3.5.4.16 0.0000000000000000000000000000000000000000000007339 171.0
HFD3_k127_2881646_0 PFAM Phenylalanine and histidine ammonia-lyase K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007378 460.0
HFD3_k127_2881646_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000003026 166.0
HFD3_k127_2886894_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 374.0
HFD3_k127_2886894_1 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000077 349.0
HFD3_k127_2886894_2 Belongs to the UPF0173 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006453 267.0
HFD3_k127_2886894_3 extracellular matrix structural constituent - - - 0.000000000000000000003065 111.0
HFD3_k127_2886894_4 AsmA-like C-terminal region K07289,K09800 - - 0.00000009883 64.0
HFD3_k127_2907737_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0040007,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004756 428.0
HFD3_k127_290864_0 Transglycosylase K05366 GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.4.1.129,3.4.16.4 1.324e-203 652.0
HFD3_k127_290864_1 PFAM Ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.00000002093 63.0
HFD3_k127_292157_0 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02481,K07713 GO:0000156,GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0023052,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035556,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 415.0
HFD3_k127_292157_1 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 379.0
HFD3_k127_292157_2 COGs COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 304.0
HFD3_k127_292157_3 TonB-dependent receptor - - - 0.000000000000000000000000000000000000004054 166.0
HFD3_k127_2978427_0 COG NOG10142 non supervised orthologous group - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 370.0
HFD3_k127_2978427_1 MarC family integral membrane protein - - - 0.000000000000000000000000000000000000000003121 158.0
HFD3_k127_2978427_2 - - - - 0.000003249 55.0
HFD3_k127_2982209_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 2.087e-212 689.0
HFD3_k127_2982209_1 domain protein K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000005513 229.0
HFD3_k127_2982209_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000008828 103.0
HFD3_k127_2982209_3 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000001245 97.0
HFD3_k127_2982209_4 Protein of unknown function (DUF503) K09764 - - 0.000000000000000796 81.0
HFD3_k127_2999520_0 HTH-like domain K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001677 281.0
HFD3_k127_2999520_1 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 0.0000000000000000000000000000000000000000000001337 171.0
HFD3_k127_2999520_2 transposase activity K07483 - - 0.0000000000000000009377 89.0
HFD3_k127_3002777_0 Cytochrome c-type biogenesis protein CcmF K02198 - - 1.192e-238 745.0
HFD3_k127_3002777_1 oxidoreductase DsbE K02199 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000396 262.0
HFD3_k127_3005216_0 Glycogen debranching enzyme - - - 0.0 1579.0
HFD3_k127_3005216_1 Predicted permease K07089 - - 1.864e-195 617.0
HFD3_k127_3005216_10 SpoVT / AbrB like domain K07172 - - 0.00000000000000000000002374 101.0
HFD3_k127_3005216_11 Thioredoxin domain - - - 0.0000000000000000000008502 97.0
HFD3_k127_3005216_12 DNA-templated transcription, initiation K03088 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.0000000004876 68.0
HFD3_k127_3005216_2 alpha amylase, catalytic region - - - 0.00000000000000000000000000000000000000000000000000000000000765 209.0
HFD3_k127_3005216_3 PFAM cytochrome c biogenesis protein, transmembrane region - - - 0.00000000000000000000000000000000000000000000000000000000001136 214.0
HFD3_k127_3005216_4 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0000000000000000000000000000000000000001042 153.0
HFD3_k127_3005216_5 Domain of unknown function (DUF1508) K09946 - - 0.0000000000000000000000000000000000000009088 150.0
HFD3_k127_3005216_6 Domain of unknown function (DUF4382) - - - 0.000000000000000000000000000000000000001287 158.0
HFD3_k127_3005216_7 helix_turn_helix, Arsenical Resistance Operon Repressor K03655,K03892 - 3.6.4.12 0.000000000000000000000000000000000005831 139.0
HFD3_k127_3005216_8 AI-2E family transporter K03548 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000000000000000000000007724 127.0
HFD3_k127_3005216_9 - - - - 0.000000000000000000000000008225 117.0
HFD3_k127_3007530_0 Amino acid permease - - - 2.544e-222 707.0
HFD3_k127_3007530_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007666 296.0
HFD3_k127_3007530_2 PFAM Methyltransferase type 11 K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000112 271.0
HFD3_k127_3007530_3 DNA-binding transcription factor activity K21886,K21903 - - 0.0000000000000001073 85.0
HFD3_k127_3007530_4 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000002586 73.0
HFD3_k127_3007530_5 - - - - 0.00000003783 62.0
HFD3_k127_3007630_0 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 381.0
HFD3_k127_3007630_1 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000001219 187.0
HFD3_k127_3007702_0 elongation factor G K02355 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944 - 2.439e-232 737.0
HFD3_k127_3031209_0 peptide catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000005434 232.0
HFD3_k127_3033222_0 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 595.0
HFD3_k127_3033222_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647,K09458,K14660 - 2.3.1.179,2.3.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 547.0
HFD3_k127_3033222_2 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000001692 228.0
HFD3_k127_3033222_3 PFAM DinB family - - - 0.0000000000000000000000000000000000000000000000007619 179.0
HFD3_k127_3033222_4 Protein similar to CwfJ C-terminus 1 K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000000003364 177.0
HFD3_k127_3033222_5 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000004706 163.0
HFD3_k127_3033222_6 Enoyl-(Acyl carrier protein) reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.000000000000000000000000000001276 122.0
HFD3_k127_3033222_7 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000004893 99.0
HFD3_k127_3040_0 Glycosyl hydrolases family 35 K01190,K12308 - 3.2.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000425 403.0
HFD3_k127_3040_1 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000002058 156.0
HFD3_k127_3054325_0 extracellular matrix structural constituent - - - 0.0000000000000000003565 94.0
HFD3_k127_3081764_0 Belongs to the FPP GGPP synthase family K00805,K02523 GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.30,2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 317.0
HFD3_k127_3081764_1 Sigma-54 interaction domain K02584,K07713,K15836,K21009 - - 0.000000000000000000000000000000000000000000000000000000000000000001236 247.0
HFD3_k127_3081764_2 Glycosyl transferase, family 9 K02843 - - 0.000000000000000000000000000000000000000000000000000000008472 224.0
HFD3_k127_3081764_3 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000005182 196.0
HFD3_k127_3081764_4 Polynucleotide kinase 3 phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000008429 162.0
HFD3_k127_3081764_5 membrane - - - 0.0000000000000000000001092 111.0
HFD3_k127_3081764_6 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000274 94.0
HFD3_k127_3081764_8 oxidoreductase activity - - - 0.0000006788 63.0
HFD3_k127_3081764_9 Protein tyrosine kinase K08884 - 2.7.11.1 0.00005215 55.0
HFD3_k127_3123688_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0042759,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005057 390.0
HFD3_k127_3123688_1 PFAM Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000001098 235.0
HFD3_k127_3123688_2 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000000000000003237 107.0
HFD3_k127_3126968_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520,K20447,K20448 - 1.17.1.5,1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000876 603.0
HFD3_k127_3126968_1 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000003679 157.0
HFD3_k127_3126968_2 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000004082 151.0
HFD3_k127_3126968_3 - - - - 0.0000000000006334 76.0
HFD3_k127_3135112_0 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000006545 243.0
HFD3_k127_3135112_1 XanTHIne and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.00000000000000000000000000000000000000008544 161.0
HFD3_k127_3135112_2 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141,K19190 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0019720,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061602,GO:0070567,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902759,GO:1902760 1.1.1.328,2.7.7.76 0.00000000000000000000000000000000005883 142.0
HFD3_k127_3135112_3 response regulator K02667 - - 0.000000000000000000000000059 113.0
HFD3_k127_3135112_4 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000116 103.0
HFD3_k127_3135112_5 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF K07402 - - 0.00000000000008541 77.0
HFD3_k127_3135112_6 ion channel K03442 - - 0.0000000000002545 82.0
HFD3_k127_3135112_7 Tricorn protease PDZ domain - - - 0.00003664 51.0
HFD3_k127_3161965_0 Large-conductance mechanosensitive channel, MscL K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.0000000000000000000000000000000000000000000000000000000006467 205.0
HFD3_k127_3161965_1 Serine phosphatase RsbU regulator of sigma subunit K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000002283 187.0
HFD3_k127_3161965_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000005047 118.0
HFD3_k127_3161965_3 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000002527 73.0
HFD3_k127_3161965_4 DinB superfamily - - - 0.000000000006663 72.0
HFD3_k127_3161965_5 Phosphoserine phosphatase - - - 0.000000000009104 74.0
HFD3_k127_316578_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000002024 238.0
HFD3_k127_3203857_0 aspartate--ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 7.342e-196 617.0
HFD3_k127_3203857_1 hydrolase - - - 0.0000000000000000000000000000000000000000000000000000005665 199.0
HFD3_k127_3203857_2 Domain of unknown function (DUF1998) K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.000000000000000000000000000000000000000000000000455 179.0
HFD3_k127_3203857_3 translation initiation factor activity K06996 - - 0.000000000000000000000000000000000000000283 153.0
HFD3_k127_3203857_4 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000004425 134.0
HFD3_k127_3203857_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.3 0.00000000000000000000000000000008316 128.0
HFD3_k127_3269168_0 Berberine and berberine like - - - 9.068e-229 716.0
HFD3_k127_3269168_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 544.0
HFD3_k127_3269168_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009073 336.0
HFD3_k127_3269168_3 PKD domain K19668,K20850 - 3.2.1.157,3.2.1.91 0.00000000000000000000000000000000000000000000000000002127 205.0
HFD3_k127_3269168_4 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000001077 172.0
HFD3_k127_3269168_5 Peptidase M1 membrane alanine aminopeptidase - - - 0.00000000000000000007075 104.0
HFD3_k127_3269168_6 M6 family metalloprotease domain protein - - - 0.00000000002352 76.0
HFD3_k127_3269168_8 Belongs to the serpin family K13963 - - 0.000000213 53.0
HFD3_k127_3269168_9 blue (type 1) copper K00368 - 1.7.2.1 0.0000003712 57.0
HFD3_k127_3275514_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 426.0
HFD3_k127_3287159_0 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001263 292.0
HFD3_k127_3287159_1 Psort location Cytoplasmic, score 9.97 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001232 280.0
HFD3_k127_3287159_2 type I phosphodiesterase nucleotide pyrophosphatase - GO:0003674,GO:0003824,GO:0004035,GO:0004346,GO:0005488,GO:0005575,GO:0005623,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008877,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046872,GO:0046914,GO:0050308,GO:0050309,GO:0098519 - 0.0000000000000000000000000000000000000000000000000000000000000000000002099 253.0
HFD3_k127_3291069_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 429.0
HFD3_k127_3291069_1 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 315.0
HFD3_k127_3291069_2 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000001267 184.0
HFD3_k127_3291069_3 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000882 169.0
HFD3_k127_3291069_4 peptide deformylase activity K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.000000000000000000000000000000000000000001921 161.0
HFD3_k127_3304363_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 415.0
HFD3_k127_3304363_1 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 412.0
HFD3_k127_3304363_2 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.0000000000000000000000000000006098 124.0
HFD3_k127_3311380_0 Helix-hairpin-helix domain K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 432.0
HFD3_k127_3311380_1 Sn-glycerol-3-phosphate dehydrogenase subunit C K00113 - 1.1.5.3 0.0000000000000000017 93.0
HFD3_k127_3311380_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000001062 57.0
HFD3_k127_3317178_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 7.268e-226 712.0
HFD3_k127_3324752_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 601.0
HFD3_k127_3324752_1 cellulose binding K00505 - 1.14.18.1 0.0000000002886 63.0
HFD3_k127_3331140_0 Belongs to the CarB family K01955 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 567.0
HFD3_k127_3331140_1 UvrD/REP helicase N-terminal domain K03656,K03657 GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.00000000000000000000000006106 112.0
HFD3_k127_3338275_0 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000001489 173.0
HFD3_k127_3338275_1 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.00000000000000000000000000000000005341 148.0
HFD3_k127_3348326_0 Sigma factor PP2C-like phosphatases K04757,K07315 - 2.7.11.1,3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 493.0
HFD3_k127_3348326_1 Tetratricopeptide repeat - - - 0.00000002264 59.0
HFD3_k127_3355969_0 Bacterial DNA polymerase III alpha subunit K02337,K14162 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000004469 252.0
HFD3_k127_3355969_1 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.000000000000001635 90.0
HFD3_k127_3357106_0 von Willebrand factor (vWF) type A domain K07114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 443.0
HFD3_k127_3357106_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000006585 183.0
HFD3_k127_3357106_2 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.0000000000000000006834 89.0
HFD3_k127_3357106_3 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000005248 69.0
HFD3_k127_3357377_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883,K15526 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065 6.1.1.16,6.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 358.0
HFD3_k127_3357377_1 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001292 286.0
HFD3_k127_3357377_2 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009097 257.0
HFD3_k127_3363545_0 Cellulase (glycosyl hydrolase family 5) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 432.0
HFD3_k127_3363545_1 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006881 391.0
HFD3_k127_3372311_0 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001106 277.0
HFD3_k127_3372311_1 ferric iron binding K02217,K02255 GO:0003674,GO:0003824,GO:0004322,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008199,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033554,GO:0042221,GO:0042592,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071241,GO:0071248,GO:0071281,GO:0097577,GO:0098771 1.16.3.2 0.000000000000000000000000000000000000000000000000004923 186.0
HFD3_k127_3372311_2 PFAM Bacterial regulatory protein, arsR family K21903 - - 0.00000000000000000000000003207 114.0
HFD3_k127_3372311_3 Methyltransferase domain - - - 0.00000000002188 73.0
HFD3_k127_3372311_4 His Kinase A (phosphoacceptor) domain - - - 0.000000653 53.0
HFD3_k127_3372311_5 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0005852 48.0
HFD3_k127_3385400_0 protein conserved in bacteria K09927 - - 0.000000000000000000000000000000000000000000000000000001632 204.0
HFD3_k127_3385400_1 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000007442 171.0
HFD3_k127_338765_0 FlgD Ig-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 329.0
HFD3_k127_338765_1 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0070566,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.00000000000000000000000000000000000000000000000002154 184.0
HFD3_k127_338765_3 RNA methyltransferase, RsmD family K08316 - 2.1.1.171 0.0000000000000000724 85.0
HFD3_k127_3393966_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 339.0
HFD3_k127_3393966_1 Belongs to the FPP GGPP synthase family K00795,K02523,K13789 GO:0003674,GO:0003824,GO:0004161,GO:0004311,GO:0004337,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009536,GO:0009842,GO:0009987,GO:0016114,GO:0016740,GO:0016765,GO:0019637,GO:0033383,GO:0033384,GO:0033385,GO:0033386,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045337,GO:0045338,GO:0071704,GO:0090407,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000005692 254.0
HFD3_k127_3393966_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000007154 164.0
HFD3_k127_3393966_3 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.0000000000000000000001835 108.0
HFD3_k127_3393966_4 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000003968 72.0
HFD3_k127_3409639_0 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000001073 191.0
HFD3_k127_3409639_1 Belongs to the UPF0403 family - - - 0.0000000000000000000000000000000000000000005345 162.0
HFD3_k127_3409639_2 Helix-turn-helix diphteria tox regulatory element K03709 - - 0.00000000000000000000000000000006986 130.0
HFD3_k127_3409639_3 OmpA family - - - 0.00000000000004482 83.0
HFD3_k127_3410234_0 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001337 287.0
HFD3_k127_3411353_0 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 2.169e-197 631.0
HFD3_k127_3411353_1 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 427.0
HFD3_k127_3411353_2 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000008668 254.0
HFD3_k127_3411353_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000007044 123.0
HFD3_k127_3452349_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1013.0
HFD3_k127_3452349_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 2.319e-311 966.0
HFD3_k127_3452349_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000001132 214.0
HFD3_k127_3452349_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000007219 209.0
HFD3_k127_3455279_0 PFAM MotA TolQ ExbB proton channel K02556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000118 282.0
HFD3_k127_3455279_1 The M ring may be actively involved in energy transduction K02409 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009428 255.0
HFD3_k127_3455279_2 response regulator K02481,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000001051 232.0
HFD3_k127_3455279_3 PFAM OmpA K02557 - - 0.0000000000000000000000000000000000000000000000002135 186.0
HFD3_k127_3455279_4 Flagellar hook-basal body complex protein FliE K02408 - - 0.0002508 50.0
HFD3_k127_3460913_0 Wd-40 repeat - - - 0.000003437 59.0
HFD3_k127_3469459_0 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 495.0
HFD3_k127_3469459_1 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000007721 244.0
HFD3_k127_3469459_2 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000001431 149.0
HFD3_k127_350520_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1108.0
HFD3_k127_350520_1 Carbon starvation protein K06200 - - 5.138e-220 695.0
HFD3_k127_350520_2 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005285 292.0
HFD3_k127_350520_3 Hep Hag repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000002377 230.0
HFD3_k127_350520_6 exo-alpha-(2->6)-sialidase activity - - - 0.00000000003471 78.0
HFD3_k127_3535137_0 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 555.0
HFD3_k127_3535137_1 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006618 423.0
HFD3_k127_3535137_2 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000000000000000000000000008179 202.0
HFD3_k127_3535137_3 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000003706 105.0
HFD3_k127_3535137_4 permease K06901 - - 0.0000000000003391 70.0
HFD3_k127_353550_0 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - 0.00000000000000000000000000000000000000000000001794 182.0
HFD3_k127_353550_1 amidohydrolase K07045 - - 0.00000000000000000000000000000000000000003818 162.0
HFD3_k127_353550_2 Rdx family K07401 - - 0.00000000009775 63.0
HFD3_k127_353550_3 Thiol-disulfide oxidoreductase - - - 0.00000001249 57.0
HFD3_k127_3554252_0 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008285 319.0
HFD3_k127_3554252_1 ABC-type transport system involved in multi-copper enzyme maturation permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 320.0
HFD3_k127_3565986_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046483,GO:0050896,GO:0051704,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 513.0
HFD3_k127_3565986_1 methyltransferase activity - - - 0.000000000000000000000000000000001143 136.0
HFD3_k127_3565986_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000001618 135.0
HFD3_k127_3565986_3 - - - - 0.00000000000000000000000000002682 125.0
HFD3_k127_3565986_4 - - - - 0.00000000000000000005212 98.0
HFD3_k127_3565986_5 PspC domain - - - 0.0000000000000000006171 88.0
HFD3_k127_3566524_0 Acyl-CoA dehydrogenase, C-terminal domain K16173 - 1.3.99.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 565.0
HFD3_k127_3566524_1 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000003576 158.0
HFD3_k127_3566524_2 Hep Hag repeat protein - - - 0.00000000001721 68.0
HFD3_k127_3571213_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 468.0
HFD3_k127_3571213_1 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000001765 225.0
HFD3_k127_3583781_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002273 289.0
HFD3_k127_3583781_1 cell adhesion involved in biofilm formation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001698 287.0
HFD3_k127_3583781_2 - K01992,K16919 - - 0.000000000000000000000000000000000000000000000000000000000000006506 234.0
HFD3_k127_3583781_3 - K01992,K16919 - - 0.00000000000000000000000000000000000000000000000000000000000009674 239.0
HFD3_k127_3583781_4 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000003928 219.0
HFD3_k127_3583781_5 spore germination - - - 0.00000000000000000000000000000000000000000004244 173.0
HFD3_k127_360761_0 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000001145 109.0
HFD3_k127_360761_1 NHL repeat containing protein - - - 0.0000000000003293 79.0
HFD3_k127_360761_2 Domain of unknown function (DUF4153) - - - 0.0000000001065 72.0
HFD3_k127_362140_0 TIGRFAM The (Largely Gram-negative Bacterial) Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 0.0 1226.0
HFD3_k127_362140_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 309.0
HFD3_k127_362140_2 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001294 268.0
HFD3_k127_362140_3 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000000000000000000000004819 111.0
HFD3_k127_3626471_0 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000002829 185.0
HFD3_k127_3626471_1 peptidyl-tyrosine sulfation K13992 - - 0.0000000000000000000000000000000000000001102 162.0
HFD3_k127_3626471_2 extracellular matrix structural constituent - - - 0.00000000000000000002189 105.0
HFD3_k127_3626471_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000005952 76.0
HFD3_k127_3635359_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 4.203e-214 687.0
HFD3_k127_3635359_1 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000001158 217.0
HFD3_k127_3635359_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000007444 119.0
HFD3_k127_3635359_3 Cupin domain - - - 0.000000000000000000007252 97.0
HFD3_k127_3635577_0 metallocarboxypeptidase activity K14054 - - 8.578e-228 737.0
HFD3_k127_3635577_1 Thrombospondin type 3 repeat - - - 0.000000000000002092 88.0
HFD3_k127_3635577_3 Periplasmic copper-binding protein (NosD) - - - 0.0001385 53.0
HFD3_k127_3640616_0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199 608.0
HFD3_k127_3640616_1 Proton-conducting membrane transporter K12141 - - 0.0000000000007114 70.0
HFD3_k127_3643704_0 - - - - 2.323e-237 748.0
HFD3_k127_3643704_1 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000000000000004192 171.0
HFD3_k127_3643704_2 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000007841 119.0
HFD3_k127_3643704_3 DNA-templated transcription, initiation K03088 - - 0.0000000000000000001367 98.0
HFD3_k127_3643704_4 - K13640 - - 0.0000000000000002121 80.0
HFD3_k127_3643704_5 DNA-templated transcription, initiation K03088 - - 0.0000000000002422 74.0
HFD3_k127_3647931_0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001403 250.0
HFD3_k127_3647931_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000008522 211.0
HFD3_k127_3647931_2 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000004686 177.0
HFD3_k127_3652824_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000003039 202.0
HFD3_k127_3656519_0 Carboxyl transferase domain K01969 - 6.4.1.4 2.728e-229 721.0
HFD3_k127_3656519_1 Acetyl propionyl-CoA carboxylase, alpha subunit K11263 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 6.3.4.14,6.4.1.2,6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006292 287.0
HFD3_k127_3656519_2 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000003748 234.0
HFD3_k127_3656519_3 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000001473 242.0
HFD3_k127_3661544_0 LOR/SDH bifunctional enzyme conserved region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004775 467.0
HFD3_k127_3661544_1 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 365.0
HFD3_k127_3661544_2 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000003836 108.0
HFD3_k127_3669603_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 539.0
HFD3_k127_3669603_1 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006443 438.0
HFD3_k127_3669603_2 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.000000000000000000000000000000000000000000000003385 179.0
HFD3_k127_3677796_0 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000656 599.0
HFD3_k127_3677796_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000003243 235.0
HFD3_k127_3768252_0 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001991 282.0
HFD3_k127_3768252_1 TIGRFAM riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000258 183.0
HFD3_k127_3768252_2 adenosine deaminase K01488,K21053 - 3.5.4.2,3.5.4.4 0.00000000000000000000000000000000000000000000005106 175.0
HFD3_k127_3768252_3 SMART Integrin alpha beta-propellor repeat protein - - - 0.000000000000000000000000000000000006166 158.0
HFD3_k127_3768252_4 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000001664 65.0
HFD3_k127_3768252_5 COG0810 Periplasmic protein TonB, links inner and outer membranes K03832 - - 0.000287 54.0
HFD3_k127_3788922_0 Glycosyltransferase family 9 (heptosyltransferase) K12982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 322.0
HFD3_k127_3788922_1 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000002225 183.0
HFD3_k127_3788922_2 Phosphoglycolate phosphatase K01091,K22292 - 3.1.3.105,3.1.3.18 0.000000000000000000000002311 115.0
HFD3_k127_3796484_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 349.0
HFD3_k127_3796484_1 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis K03816 - 2.4.2.22 0.000000000000000000000000000000000000000000000002091 175.0
HFD3_k127_3796484_2 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family K02503 - - 0.0000000135 62.0
HFD3_k127_3809759_0 ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000002332 233.0
HFD3_k127_3809759_1 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000002664 132.0
HFD3_k127_3826714_0 transcription factor binding K02584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003661 295.0
HFD3_k127_3826714_1 histidine kinase A domain protein - - - 0.00000000003132 74.0
HFD3_k127_3838198_0 domain protein K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004067 368.0
HFD3_k127_3838198_1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07658 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001185 254.0
HFD3_k127_3838198_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000002989 193.0
HFD3_k127_3838198_3 Domain of unknown function (DUF1949) - - - 0.00000000000000000000000000000000000004448 154.0
HFD3_k127_3838198_4 PFAM OsmC family protein K07397 - - 0.0000000000000001327 85.0
HFD3_k127_3838198_5 FR47-like protein - - - 0.000000003289 68.0
HFD3_k127_3838198_6 pfkB family carbohydrate kinase K00847,K00852 - 2.7.1.15,2.7.1.4 0.000001984 53.0
HFD3_k127_3845651_0 histidine kinase HAMP region domain protein K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 305.0
HFD3_k127_3845651_1 - - - - 0.000009105 56.0
HFD3_k127_3850308_0 ABC-type multidrug transport system ATPase and permease K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001292 275.0
HFD3_k127_3850308_1 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000512 136.0
HFD3_k127_3850308_2 Phosphotransferase enzyme family - - - 0.00000000000000000002804 106.0
HFD3_k127_3875456_0 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K07804 - - 0.00000000000000000000000000000000000000000000000000000003543 207.0
HFD3_k127_3875456_1 YceI-like domain - - - 0.000000000000000000000000000000001299 140.0
HFD3_k127_3875456_2 hyperosmotic response - - - 0.000000000000000000009784 102.0
HFD3_k127_3875456_3 COG3209 Rhs family protein - - - 0.000000000002735 73.0
HFD3_k127_3875456_4 Lactonase, 7-bladed beta-propeller - - - 0.00000000007966 74.0
HFD3_k127_3875456_5 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00005664 49.0
HFD3_k127_3890363_0 phosphorelay signal transduction system K02584,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001655 259.0
HFD3_k127_3890363_1 Uncharacterised protein family (UPF0149) K07039 - - 0.0000000000000000000004854 105.0
HFD3_k127_3890363_2 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.000000000000000000004594 106.0
HFD3_k127_3890363_3 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000001867 83.0
HFD3_k127_3891999_0 Belongs to the thiolase family K00626,K07508 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 470.0
HFD3_k127_3891999_1 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 430.0
HFD3_k127_3891999_2 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006448 406.0
HFD3_k127_3891999_3 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 357.0
HFD3_k127_3891999_4 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009082 326.0
HFD3_k127_3891999_5 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000001626 259.0
HFD3_k127_3891999_6 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000001656 216.0
HFD3_k127_3891999_7 Dna alkylation repair - - - 0.00000000000000000000004751 108.0
HFD3_k127_3891999_8 - - - - 0.00000000000003954 77.0
HFD3_k127_390541_0 IgA Peptidase M64 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005063 265.0
HFD3_k127_3907257_0 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000004072 208.0
HFD3_k127_3907257_1 histidine kinase HAMP region domain protein - - - 0.0000000000000000000000000000000000000000002091 179.0
HFD3_k127_3907257_2 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000001789 139.0
HFD3_k127_3907257_3 - - - - 0.000000000000000104 93.0
HFD3_k127_3913302_0 Nickel-dependent hydrogenase K14126 - 1.8.98.5 4.066e-204 647.0
HFD3_k127_3913302_1 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 446.0
HFD3_k127_3913302_2 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 406.0
HFD3_k127_3913302_3 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 385.0
HFD3_k127_3913302_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000005407 235.0
HFD3_k127_3913302_5 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000231 197.0
HFD3_k127_3913302_6 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.0000000000000000009435 88.0
HFD3_k127_3913302_7 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.000000000000001297 90.0
HFD3_k127_3913302_8 Hydrogenase maturation protease K03605 - - 0.00000000000001841 81.0
HFD3_k127_3913302_9 nickel cation binding K04651 - - 0.00001029 52.0
HFD3_k127_3934787_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007241 358.0
HFD3_k127_3934787_1 Protein of unknown function DUF47 K02039,K07220 GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.0000000000000000000000000000000000000000000000000022 198.0
HFD3_k127_3934787_2 TIGRFAM cytochrome C family protein - - - 0.00000000000000000000000000002692 121.0
HFD3_k127_3937763_0 Glycosyltransferase family 20 K16055 - 2.4.1.15,3.1.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 523.0
HFD3_k127_3937763_1 trehalose biosynthetic process K01087 - 3.1.3.12 0.00000000000000000000001287 107.0
HFD3_k127_3984499_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 2.269e-278 865.0
HFD3_k127_3984499_1 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240,K00245 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 353.0
HFD3_k127_3984499_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.0000299 48.0
HFD3_k127_3994026_0 TonB-dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001058 271.0
HFD3_k127_3994026_1 Inositol monophosphatase K01082,K01092 GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000002494 258.0
HFD3_k127_3994026_2 Protein of unknown function (DUF420) - - - 0.000000000000000000000000000000000000000005583 158.0
HFD3_k127_3994026_3 protein SCO1 SenC K07152 - - 0.0000000000000000000000000000000001204 140.0
HFD3_k127_4011529_0 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007477 468.0
HFD3_k127_4011529_1 Predicted membrane protein (DUF2238) K08984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001053 272.0
HFD3_k127_4011529_2 - - - - 0.000000000000000000000000000000000000000000002697 178.0
HFD3_k127_4011529_3 - - - - 0.000000000000000000000000002512 118.0
HFD3_k127_4011529_4 - - - - 0.00000000000000000000000000288 125.0
HFD3_k127_4024007_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 296.0
HFD3_k127_4024007_1 Cytochrome C oxidase, cbb3-type, subunit III K02275 - 1.9.3.1 0.00000000096 67.0
HFD3_k127_4029437_0 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000584 253.0
HFD3_k127_4029437_1 sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000166 201.0
HFD3_k127_407359_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 543.0
HFD3_k127_407359_1 Penicillin-binding protein 2 K05515 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 514.0
HFD3_k127_407359_10 - - - - 0.0000000000000000000000000000007277 129.0
HFD3_k127_407359_11 regulation of cell shape K03570 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0030428,GO:0031224,GO:0031226,GO:0042546,GO:0043621,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944,GO:0071963 - 0.00000000000000000000001336 110.0
HFD3_k127_407359_12 Belongs to the UPF0434 family K09791 - - 0.00000000006584 70.0
HFD3_k127_407359_13 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.00001828 56.0
HFD3_k127_407359_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 380.0
HFD3_k127_407359_3 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 348.0
HFD3_k127_407359_4 Phage integrase, N-terminal SAM-like domain K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000224 267.0
HFD3_k127_407359_5 Diguanylate cyclase, GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009817 269.0
HFD3_k127_407359_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000003741 249.0
HFD3_k127_407359_7 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02768,K02769,K02770,K02806 - 2.7.1.202 0.000000000000000000000000000000000000000000000000000000007696 201.0
HFD3_k127_407359_8 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000001022 203.0
HFD3_k127_407359_9 competence protein - - - 0.0000000000000000000000000000005058 131.0
HFD3_k127_4082521_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 543.0
HFD3_k127_4082521_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000569 92.0
HFD3_k127_4082521_2 Endoribonuclease that initiates mRNA decay K18682 - - 0.0000000000006036 77.0
HFD3_k127_4082521_3 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000001552 62.0
HFD3_k127_4087392_0 DNA-templated transcription, initiation K02405 - - 0.00008968 50.0
HFD3_k127_4133953_0 Domain of unknown function (DUF5117) - - - 4.308e-249 787.0
HFD3_k127_4133953_1 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 504.0
HFD3_k127_4133953_2 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007005 459.0
HFD3_k127_4133953_3 Adenylate cyclase - - - 0.00000000000000000000001233 107.0
HFD3_k127_4161018_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007983 459.0
HFD3_k127_4161018_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 297.0
HFD3_k127_4161018_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000002305 122.0
HFD3_k127_4164045_0 Radical SAM superfamily K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000002345 260.0
HFD3_k127_4164045_1 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000006047 161.0
HFD3_k127_4164045_2 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000008754 125.0
HFD3_k127_4164045_3 PFAM Bacterial regulatory protein, arsR family K22298 - - 0.00000000000000000002118 93.0
HFD3_k127_4164045_4 Cupin domain - - - 0.000000000000000004109 94.0
HFD3_k127_4164913_0 PFAM AbgT K12942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003565 341.0
HFD3_k127_4164913_1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003992 281.0
HFD3_k127_4164913_2 LVIVD repeat K01179 - 3.2.1.4 0.000000000005895 78.0
HFD3_k127_4164913_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.00000004754 65.0
HFD3_k127_4164913_4 YtxH-like protein - - - 0.0000001917 56.0
HFD3_k127_4168306_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K17050 - 1.7.5.1,1.8.5.3 0.0 1388.0
HFD3_k127_4168306_1 PFAM Cytochrome b b6 domain - - - 1.375e-200 637.0
HFD3_k127_4168306_2 nitrate reductase beta subunit K00371,K17051 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007211 533.0
HFD3_k127_4168306_3 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003072 295.0
HFD3_k127_4168306_4 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.00000000000000000000000000000000000000000000000000000000000002863 220.0
HFD3_k127_4168306_5 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000000003342 127.0
HFD3_k127_4168306_6 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.000000007344 64.0
HFD3_k127_4171152_0 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 399.0
HFD3_k127_4171152_1 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000002442 119.0
HFD3_k127_4189417_0 Thermolysin metallopeptidase, catalytic domain K01400 - 3.4.24.28 0.0000000000000000000000000000000000000000000000000000000002388 231.0
HFD3_k127_4196901_0 Metallopeptidase family M24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 375.0
HFD3_k127_4196901_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001297 252.0
HFD3_k127_4196901_2 GDP-mannose mannosyl hydrolase activity K03574 - 3.6.1.55 0.0000000000000000000000000000001745 132.0
HFD3_k127_4196901_3 Methylated dna-protein cysteine methyltransferase K07443 - - 0.000000000000000000000000000354 119.0
HFD3_k127_4197824_0 CHAT domain - - - 0.00000000000000000000000000000000000000000004353 185.0
HFD3_k127_4197824_1 RNA polymerase, sigma-24 subunit, ECF subfamily - - - 0.0000000000000000000000007226 111.0
HFD3_k127_4197824_2 - - - - 0.0000000008367 70.0
HFD3_k127_4214649_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000714 448.0
HFD3_k127_4214649_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 439.0
HFD3_k127_4214649_10 phosphorelay signal transduction system K02584,K07713 - - 0.000001976 58.0
HFD3_k127_4214649_2 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003913 398.0
HFD3_k127_4214649_3 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 320.0
HFD3_k127_4214649_4 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 312.0
HFD3_k127_4214649_5 Protein of unknown function (DUF1385) K09153 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001102 267.0
HFD3_k127_4214649_6 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000002467 249.0
HFD3_k127_4214649_7 DegT DnrJ EryC1 StrS aminotransferase K07806 - 2.6.1.87 0.00000000000000000000000000000002131 134.0
HFD3_k127_4214649_8 Binds the 23S rRNA K02909 - - 0.000000000000000000000000002058 115.0
HFD3_k127_4214649_9 SMART helix-turn-helix - - - 0.0000000411 63.0
HFD3_k127_4218008_0 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000002025 234.0
HFD3_k127_4218008_1 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000002047 216.0
HFD3_k127_4218008_2 cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000004902 192.0
HFD3_k127_4218008_3 membrane K15977 - - 0.0000000000000000000000000000000000002288 147.0
HFD3_k127_4218008_4 divalent heavy-metal cations transporter - - - 0.000000000000000000000000000000000004723 147.0
HFD3_k127_4238315_0 PQQ enzyme repeat - - - 0.0004119 54.0
HFD3_k127_4242539_0 binding-protein-dependent transport systems inner membrane component K02025,K15771 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006048 289.0
HFD3_k127_4242539_1 maltose binding K02027,K17329 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000825 284.0
HFD3_k127_4242539_2 binding-protein-dependent transport systems inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000441 282.0
HFD3_k127_4242539_3 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000000000000003576 102.0
HFD3_k127_4249222_0 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000002848 242.0
HFD3_k127_4249222_1 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01450,K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.31,3.5.1.88 0.000000000000000000000000000000000003977 143.0
HFD3_k127_4249222_2 Preprotein translocase, YajC K03210 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000073 109.0
HFD3_k127_4283839_0 Acetyl-CoA hydrolase/transferase N-terminal domain K01067 - 3.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006296 562.0
HFD3_k127_4283839_1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 432.0
HFD3_k127_4283839_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175,K00177,K00187 - 1.2.7.11,1.2.7.3,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 319.0
HFD3_k127_4283839_3 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000001167 185.0
HFD3_k127_4283839_4 Histidine kinase HAMP K02482 - 2.7.13.3 0.000000000000000000000000000000000000000008984 166.0
HFD3_k127_4290166_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 381.0
HFD3_k127_4290166_1 FlgD Ig-like domain K15924 - 3.2.1.136 0.00000000000000000000000000000002091 141.0
HFD3_k127_4290166_2 Binds directly to 16S ribosomal RNA K02968 - - 0.000000003503 60.0
HFD3_k127_4290166_3 chromosome segregation K03497 - - 0.0000007992 60.0
HFD3_k127_4299646_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 9.353e-307 960.0
HFD3_k127_4299646_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000008305 233.0
HFD3_k127_4306830_0 peptidase S9 prolyl oligopeptidase active site K01303 - 3.4.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 492.0
HFD3_k127_4306830_1 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 394.0
HFD3_k127_430996_0 Peptidase M16 inactive domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 468.0
HFD3_k127_430996_1 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000003107 136.0
HFD3_k127_431435_0 copper resistance - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 361.0
HFD3_k127_431435_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006497 346.0
HFD3_k127_432215_0 SAICAR synthetase K01923,K01945,K03566 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006568 347.0
HFD3_k127_432215_1 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.00000000000000000000000000000000000007984 160.0
HFD3_k127_432215_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 2.1.2.2 0.00000000008849 63.0
HFD3_k127_432878_0 ABC transporter K06158 - - 0.00000000000000000000003668 105.0
HFD3_k127_432878_1 Tetratricopeptide repeat - - - 0.0000000002108 74.0
HFD3_k127_4335450_0 CHAT domain - - - 0.000000000000000000000000000000000000000000000000000000000006441 236.0
HFD3_k127_4335450_1 Belongs to the peptidase S8 family K08651,K14743 - 3.4.21.66 0.000000000000000000000000000000000000000000000000001361 201.0
HFD3_k127_4335450_2 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000006938 115.0
HFD3_k127_4335450_3 Belongs to the sigma-70 factor family - - - 0.000000000000000000000000004993 119.0
HFD3_k127_4335450_4 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.00000000000000002947 84.0
HFD3_k127_4335450_5 Involved in the tonB-independent uptake of proteins K03640 - - 0.000000000452 72.0
HFD3_k127_4373997_0 AcrB/AcrD/AcrF family - - - 3.093e-297 929.0
HFD3_k127_4383421_0 COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003879 494.0
HFD3_k127_4383421_1 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 364.0
HFD3_k127_4383421_2 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.000000000000000000000000000000000000000000000000000002015 199.0
HFD3_k127_4383421_3 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.5.1.129 0.0000000000000000000000000000000000000109 154.0
HFD3_k127_4383421_4 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000000000000165 134.0
HFD3_k127_4397757_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 8.541e-235 752.0
HFD3_k127_4397757_1 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005992 583.0
HFD3_k127_4397757_2 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007616 474.0
HFD3_k127_4397757_3 phosphoserine phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005483 295.0
HFD3_k127_4397757_4 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000001045 123.0
HFD3_k127_4397757_5 YceI-like domain - - - 0.0000000000000000000001324 113.0
HFD3_k127_4397757_6 Cell wall-active antibiotics response 4TMS YvqF K11622 - - 0.000000000001601 78.0
HFD3_k127_4397757_7 Modulates RecA activity K03565 - - 0.000000007917 63.0
HFD3_k127_4406201_0 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000000000000000000000002697 228.0
HFD3_k127_4406201_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.000000003282 57.0
HFD3_k127_4406201_2 HsdM N-terminal domain K03427 - 2.1.1.72 0.000001775 51.0
HFD3_k127_441802_0 ABC-type multidrug transport system ATPase and permease K06147 - - 0.000000000000000000000000000000000000000000000000000000007251 211.0
HFD3_k127_441802_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000007005 172.0
HFD3_k127_4435892_0 TamB, inner membrane protein subunit of TAM complex K07277,K09800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 366.0
HFD3_k127_4435892_1 Surface antigen K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 347.0
HFD3_k127_4435892_2 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000235 176.0
HFD3_k127_446072_0 Dehydrogenase E1 component K11381 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 576.0
HFD3_k127_446072_1 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007174 446.0
HFD3_k127_446072_2 - K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.000000000000000000000000002537 116.0
HFD3_k127_446072_3 O-Antigen ligase K16567 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0007768 49.0
HFD3_k127_4519795_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 3.059e-235 742.0
HFD3_k127_4519795_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016625,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0047553,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005701 464.0
HFD3_k127_4519795_2 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001364 278.0
HFD3_k127_4519795_3 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K07083,K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004888 261.0
HFD3_k127_4519795_4 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000017 98.0
HFD3_k127_4519795_5 CBS domain-containing protein - - - 0.00000000002676 74.0
HFD3_k127_452653_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840,K15778 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 544.0
HFD3_k127_452653_1 Cytochrome bd-type quinol oxidase subunit 1 K00425 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 526.0
HFD3_k127_452653_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006566 343.0
HFD3_k127_452653_3 Belongs to the ABC transporter superfamily K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 338.0
HFD3_k127_452653_4 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001542 287.0
HFD3_k127_452653_5 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000004795 244.0
HFD3_k127_452653_6 Participates in initiation and elongation during chromosome replication K02314 GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 0.0000000000000000000000000000000000000000000000000002144 191.0
HFD3_k127_452653_8 phosphorelay signal transduction system K02490 - - 0.00000000000000000000000000000000000000000000000596 181.0
HFD3_k127_4536593_0 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 345.0
HFD3_k127_4536593_1 response regulator K07782 - - 0.00000000000000000000000000000000000000000000000002546 188.0
HFD3_k127_4536593_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000002247 146.0
HFD3_k127_4536593_3 Bacterial Ig-like domain (group 1) - - - 0.000000000000001962 83.0
HFD3_k127_4536593_5 Sigma-70, region 4 K03088 - - 0.00002499 52.0
HFD3_k127_4543253_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1022.0
HFD3_k127_4543253_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000005774 139.0
HFD3_k127_4543253_2 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.00000000000000000002921 94.0
HFD3_k127_4545057_0 PPIC-type PPIASE domain K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 342.0
HFD3_k127_4545057_1 PPIC-type PPIASE domain K03769,K07533 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 315.0
HFD3_k127_4545057_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004785 297.0
HFD3_k127_4545057_3 phosphorelay signal transduction system - - - 0.00000000000000000000000000001624 122.0
HFD3_k127_4545057_4 - - - - 0.000000000000000000002602 102.0
HFD3_k127_4545057_5 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.00000000000000000003912 96.0
HFD3_k127_4565963_0 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 338.0
HFD3_k127_4565963_1 Elongation factor SelB, winged helix K03833 GO:0000049,GO:0000166,GO:0001514,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006412,GO:0006414,GO:0006417,GO:0006451,GO:0006518,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009069,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016259,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034248,GO:0034641,GO:0034645,GO:0035368,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 321.0
HFD3_k127_4565963_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 334.0
HFD3_k127_4565963_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000001481 248.0
HFD3_k127_4565963_4 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000000000000000000000000000000000001066 230.0
HFD3_k127_4565963_5 YbaB/EbfC DNA-binding family K09747 - - 0.00000000000000000000000001387 113.0
HFD3_k127_4565963_6 Chaperone of endosialidase - - - 0.000000009758 59.0
HFD3_k127_457152_0 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000009976 220.0
HFD3_k127_457152_1 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000000000000000000000000000000000000002307 197.0
HFD3_k127_457152_2 - - - - 0.0000000000000000000000000000000000000001808 157.0
HFD3_k127_457152_3 - - - - 0.0000000000000000000000000000000000001148 154.0
HFD3_k127_457152_4 Belongs to the peptidase S11 family K07262 - - 0.00000000000000000000000000000001382 140.0
HFD3_k127_457152_5 Rhodanese Homology Domain - - - 0.000000000000001557 85.0
HFD3_k127_4575929_0 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 507.0
HFD3_k127_4575929_1 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000223 163.0
HFD3_k127_4575929_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000003904 163.0
HFD3_k127_4575929_3 Tetratricopeptide repeat - - - 0.00000000000001378 84.0
HFD3_k127_458244_0 Aminotransferase K00812,K10907 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007385 475.0
HFD3_k127_458244_1 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 365.0
HFD3_k127_4582730_0 Vitamin B12 dependent methionine synthase, activation K00548 - 2.1.1.13 0.0 1373.0
HFD3_k127_4582730_1 GTP-binding protein TypA K06207 - - 2.566e-236 745.0
HFD3_k127_4582730_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009831 420.0
HFD3_k127_4582730_3 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000009156 258.0
HFD3_k127_4587108_0 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 464.0
HFD3_k127_4587108_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 339.0
HFD3_k127_4587108_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006037 297.0
HFD3_k127_4587108_3 - - - - 0.0000000000000000002031 91.0
HFD3_k127_4592824_0 Regulatory protein K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 376.0
HFD3_k127_4593352_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 5.242e-278 881.0
HFD3_k127_4593352_1 Heat shock 70 kDa protein K04043 - - 1.022e-268 848.0
HFD3_k127_4593352_10 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00002906 54.0
HFD3_k127_4593352_2 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004367 483.0
HFD3_k127_4593352_3 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006444 284.0
HFD3_k127_4593352_4 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000000003175 179.0
HFD3_k127_4593352_5 TIGRFAM maf protein K06287 - - 0.0000000000000000000000000000000003655 142.0
HFD3_k127_4593352_6 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000006826 136.0
HFD3_k127_4593352_8 PQQ-like domain - - - 0.000000000000006248 87.0
HFD3_k127_4593352_9 Helix-turn-helix domain K15539 - - 0.0000003583 61.0
HFD3_k127_4595441_0 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009576 568.0
HFD3_k127_4595441_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 478.0
HFD3_k127_4595441_2 Amidohydrolase family K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008839 332.0
HFD3_k127_4595441_3 Histidine kinase K19661 - 2.7.13.3 0.000000000000000000000005707 102.0
HFD3_k127_4595441_5 peptidyl-tyrosine sulfation - - - 0.0000008332 60.0
HFD3_k127_4625918_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 3.152e-234 734.0
HFD3_k127_4625918_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000002638 128.0
HFD3_k127_4712300_0 protein conserved in bacteria K09800 - - 0.000000000000000000000000000000000000000000000000000000000199 222.0
HFD3_k127_4712300_1 Aldehyde dehydrogenase family K00128 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000002668 195.0
HFD3_k127_4746735_0 Tricorn protease homolog - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 350.0
HFD3_k127_4751012_0 Surface antigen variable number K07278 - - 0.000000000000000000000000000000000000000000000000000005361 200.0
HFD3_k127_4751012_1 cytochrome C peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000005826 181.0
HFD3_k127_4758140_0 PFAM Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000043 488.0
HFD3_k127_4758140_1 Sodium:sulfate symporter transmembrane region K03319,K14445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002137 273.0
HFD3_k127_4758140_2 Lamin Tail Domain - - - 0.00000000000000000001863 106.0
HFD3_k127_4763266_0 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001135 256.0
HFD3_k127_4763266_1 Cys/Met metabolism PLP-dependent enzyme K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000009283 209.0
HFD3_k127_4786260_0 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005563 275.0
HFD3_k127_4786260_1 PFAM Methyltransferase type 12 - - - 0.000000000000000000000000000832 124.0
HFD3_k127_4786260_2 FR47-like protein - - - 0.000000000000001191 83.0
HFD3_k127_4786260_3 PFAM Adenylate cyclase K05873 - 4.6.1.1 0.0000000005937 68.0
HFD3_k127_4786260_4 response to ionizing radiation K03726 - - 0.0000001368 61.0
HFD3_k127_4786260_5 HDOD domain - - - 0.00005705 54.0
HFD3_k127_4805547_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005465 402.0
HFD3_k127_4805547_1 phosphorelay signal transduction system K02481,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006856 344.0
HFD3_k127_4808241_0 Peptidase S9, prolyl oligopeptidase, catalytic domain K01354 - 3.4.21.83 1.786e-263 829.0
HFD3_k127_4808241_1 Aldehyde dehydrogenase family K00294 - 1.2.1.88 2.33e-230 724.0
HFD3_k127_4808241_2 ketoglutarate semialdehyde dehydrogenase K14519 - 1.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006782 419.0
HFD3_k127_4808241_3 Thrombospondin type 3 repeat - - - 0.0000000000000000000000000000000000001019 156.0
HFD3_k127_4813611_0 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000006344 155.0
HFD3_k127_4813611_1 Protein of unknown function DUF72 - - - 0.0000000000000000000002094 104.0
HFD3_k127_4813611_2 Hep Hag repeat protein - - - 0.0000000000000000474 94.0
HFD3_k127_4830443_0 TOBE domain K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000002326 184.0
HFD3_k127_4830443_1 ABC-type molybdate transport system, permease component K02018 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000002093 172.0
HFD3_k127_4830443_2 ABC transporter substrate-binding protein K02020 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0042597,GO:0043167,GO:0043168,GO:0044464 - 0.000000001549 63.0
HFD3_k127_4843315_0 Methylenetetrahydrofolate reductase K00297,K00547,K00548 - 1.5.1.20,2.1.1.10,2.1.1.13 1.782e-214 683.0
HFD3_k127_4843315_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 382.0
HFD3_k127_4843315_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.000000000000000000000000000000000000000000000000000000003209 207.0
HFD3_k127_4843315_3 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000021 196.0
HFD3_k127_4843315_4 PFAM Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000000001579 153.0
HFD3_k127_4843315_5 phosphorelay signal transduction system - - - 0.0000000000000000000000000000007246 142.0
HFD3_k127_4843315_6 PFAM Histidine triad (HIT) protein K02503 - - 0.0000000000000000000000000002161 117.0
HFD3_k127_4856252_0 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000046 359.0
HFD3_k127_4856252_1 ABC transporter K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 324.0
HFD3_k127_4856252_2 Transcriptional regulator - - - 0.000000000000000000000000000000004329 134.0
HFD3_k127_4856252_3 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000004188 89.0
HFD3_k127_4863835_0 COG3119 Arylsulfatase A and related enzymes K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 390.0
HFD3_k127_4863835_1 Peptidase M16 inactive domain K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008362 282.0
HFD3_k127_4863835_2 Protein of unknown function, DUF481 - - - 0.00000000000000000000000000000000001192 149.0
HFD3_k127_4863835_3 Insulinase (Peptidase family M16) - - - 0.000000000000000004608 87.0
HFD3_k127_4871494_0 Glutamine amidotransferase class-I K01937 - 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000001251 246.0
HFD3_k127_4871494_1 Putative member of DMT superfamily (DUF486) K09922 - - 0.000000000000000000000000000000000000000000000000002905 184.0
HFD3_k127_4871494_2 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000001524 176.0
HFD3_k127_4908982_0 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008988 299.0
HFD3_k127_4908982_1 PFAM Three-deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000001406 182.0
HFD3_k127_4908982_2 inositol 2-dehydrogenase activity K09949 - - 0.0000000000000000000000000003708 119.0
HFD3_k127_491334_0 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.00000000000000000000000000000000000000000000000000000000000000000000000000001184 270.0
HFD3_k127_491334_1 protocatechuate 3,4-dioxygenase activity K00449 - 1.13.11.3 0.00000000000000000000000000000000000000000000000000000000009966 213.0
HFD3_k127_491334_2 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000001054 175.0
HFD3_k127_491334_3 Helix-turn-helix XRE-family like proteins K07729 - - 0.0000000000000000002269 95.0
HFD3_k127_491334_6 - - - - 0.00000000001005 70.0
HFD3_k127_4918752_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.3.1.29,2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003323 537.0
HFD3_k127_4918752_1 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 450.0
HFD3_k127_4918752_2 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 380.0
HFD3_k127_492071_0 TIGRFAM flagellar hook-associated protein FlgK K02396 - - 0.000000000000000000000000000000000000000000000000000000000000000002686 243.0
HFD3_k127_493746_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 455.0
HFD3_k127_493746_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00337,K00338 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000001242 245.0
HFD3_k127_493746_2 e3 binding domain K00658,K09699 GO:0003674,GO:0003824,GO:0004149,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008289,GO:0009060,GO:0009987,GO:0015980,GO:0016417,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016751,GO:0016999,GO:0017144,GO:0019752,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:0140096,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 2.3.1.168,2.3.1.61 0.000000000000000000000000000000000000000004321 168.0
HFD3_k127_493746_3 Fe-S iron-sulfur cluster assembly protein, NifU family K04488 - - 0.0000000000000000000000000000000007897 134.0
HFD3_k127_493746_4 NUDIX domain K03575 - - 0.0000000000000000000000000000387 119.0
HFD3_k127_496832_0 Stage II sporulation protein K06381 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001205 269.0
HFD3_k127_496832_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000000003721 240.0
HFD3_k127_496832_2 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000005392 237.0
HFD3_k127_496832_3 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000002967 179.0
HFD3_k127_496832_4 phosphorelay signal transduction system K02481,K07712 - - 0.00000000000000000000000000000000000000000199 159.0
HFD3_k127_499345_0 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 416.0
HFD3_k127_499345_1 NlpE C-terminal OB domain - - - 0.00000000000000000000000000000000000000000000000000000000001278 221.0
HFD3_k127_499345_2 guanyl-nucleotide exchange factor activity - - - 0.0000000000000000000000003862 121.0
HFD3_k127_499345_3 domain, Protein - - - 0.0000000000000000000002593 112.0
HFD3_k127_499345_4 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000002812 86.0
HFD3_k127_5009353_0 ATPase associated with various cellular K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006901 445.0
HFD3_k127_5009353_1 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520,K20447,K20448 - 1.17.1.5,1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008382 361.0
HFD3_k127_5009353_2 von Willebrand factor (vWF) type A domain K07114,K12511 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 312.0
HFD3_k127_5009353_3 protein (some members contain a von Willebrand factor type A (vWA) domain - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000998 291.0
HFD3_k127_5009353_4 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000001141 223.0
HFD3_k127_5009353_5 Oxygen tolerance - - - 0.0000000000000000000003977 109.0
HFD3_k127_5009353_6 - - - - 0.0000000000000001793 91.0
HFD3_k127_5009353_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000001565 72.0
HFD3_k127_5009353_8 peptidyl-tyrosine sulfation K07114 - - 0.0000000009505 70.0
HFD3_k127_5013700_0 Sortilin, neurotensin receptor 3, - - - 4.559e-309 965.0
HFD3_k127_5013700_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 554.0
HFD3_k127_5013700_2 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 380.0
HFD3_k127_5013700_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008075 391.0
HFD3_k127_5013700_4 - - - - 0.00000000000000000000000000000000000000001379 159.0
HFD3_k127_5013700_5 PFAM glucosamine galactosamine-6-phosphate isomerase K01057 - 3.1.1.31 0.000000000000000000000000000000000000003998 155.0
HFD3_k127_5013700_7 RNA recognition motif - - - 0.00000000000000000000000002723 111.0
HFD3_k127_5013700_8 Glucose-6-phosphate dehydrogenase subunit - - - 0.000000000002009 79.0
HFD3_k127_5017486_0 Sodium/calcium exchanger protein K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 392.0
HFD3_k127_5017486_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 391.0
HFD3_k127_5017486_2 membrane - - - 0.00000000000000000000000000000000000000000000000000000000149 209.0
HFD3_k127_5017486_3 - - - - 0.0000000000000000000000000000000009151 138.0
HFD3_k127_5017486_4 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.000001225 51.0
HFD3_k127_5023398_0 long-chain fatty acid transport protein - - - 0.000000000000000000000000000000000000001515 157.0
HFD3_k127_5023398_2 DinB family - - - 0.00000000001515 74.0
HFD3_k127_5023398_3 Recombinase zinc beta ribbon domain - - - 0.0002298 44.0
HFD3_k127_502954_0 Surface antigen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007391 321.0
HFD3_k127_502954_1 - - - - 0.00000000000005185 81.0
HFD3_k127_5050022_0 SIS domain K03271 - 5.3.1.28 0.00000000000000000000000000001721 121.0
HFD3_k127_5050022_2 PFAM O-antigen polymerase - - - 0.000000003523 69.0
HFD3_k127_5054121_0 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 513.0
HFD3_k127_5054121_1 Protein of unknown function DUF72 - - - 0.00000000000000003361 83.0
HFD3_k127_5073250_0 Cytochrome C biogenesis protein transmembrane region K06196,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007371 288.0
HFD3_k127_5073250_1 RNA polymerase sigma factor K03088 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.0000000000000000000000000000000000000000008047 164.0
HFD3_k127_5073250_2 creatininase K01470 - 3.5.2.10 0.000000000000000000000000004964 116.0
HFD3_k127_5073250_3 Putative zinc-finger - - - 0.0001828 53.0
HFD3_k127_5090384_0 FlgD Ig-like domain - - - 0.0000000000000000000000000000000000000000000003816 183.0
HFD3_k127_5090384_1 EVE domain - - - 0.000000000000000000000000000000000001114 144.0
HFD3_k127_5090384_2 COGs COG0491 Zn-dependent hydrolase including glyoxylase - - - 0.000000000000000000000003333 102.0
HFD3_k127_5090384_3 extracellular matrix structural constituent - - - 0.000000000000003834 85.0
HFD3_k127_5091589_0 hydrolase - - - 0.00000000000000000001244 100.0
HFD3_k127_5091589_1 von Willebrand factor type A domain K07114 - - 0.000000003428 66.0
HFD3_k127_5094634_0 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 419.0
HFD3_k127_5094634_1 Thermolysin metallopeptidase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001437 284.0
HFD3_k127_5094634_2 translation initiation factor activity K03699 - - 0.00000000000006698 75.0
HFD3_k127_5094634_3 malic enzyme K00028 GO:0000166,GO:0003674,GO:0003824,GO:0004470,GO:0004471,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006090,GO:0006108,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009507,GO:0009536,GO:0009987,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0017076,GO:0019752,GO:0030554,GO:0031974,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0050897,GO:0055114,GO:0070013,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.1.1.39 0.000000000005743 69.0
HFD3_k127_5094634_4 exo-alpha-(2->6)-sialidase activity - - - 0.000000001165 72.0
HFD3_k127_5094634_5 Lamin Tail Domain - - - 0.000004531 61.0
HFD3_k127_5098938_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 404.0
HFD3_k127_5098938_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000577 271.0
HFD3_k127_5098938_2 C4-type zinc ribbon domain K07164,K22391 - 3.5.4.16 0.0001754 45.0
HFD3_k127_5098968_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 2.638e-224 710.0
HFD3_k127_5127060_0 ABC transporter transmembrane region K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005167 404.0
HFD3_k127_5127060_1 - - - - 0.0000000000000000000000000000000000000000000000002195 183.0
HFD3_k127_5127060_2 Hep Hag repeat protein K01406 - 3.4.24.40 0.00000000000000000000006445 113.0
HFD3_k127_5127060_4 B12 binding domain - - - 0.00002373 52.0
HFD3_k127_5138831_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 4.563e-251 782.0
HFD3_k127_5138831_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 2.995e-202 633.0
HFD3_k127_5138831_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000000000000000007682 259.0
HFD3_k127_5138831_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000787 99.0
HFD3_k127_5166027_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000001025 175.0
HFD3_k127_5166027_1 Cysteine-rich CPXCG - - - 0.00000000000006646 73.0
HFD3_k127_5166027_2 ATPases associated with a variety of cellular activities - - - 0.00000008366 57.0
HFD3_k127_5171650_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000582 245.0
HFD3_k127_5171650_1 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000009195 149.0
HFD3_k127_5174658_0 (ABC) transporter K06147,K18890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000083 616.0
HFD3_k127_5174658_1 (ABC) transporter K06147,K18889 - - 0.0000000000000000000000000000000000000000000000000000000000000000002282 233.0
HFD3_k127_5178944_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 419.0
HFD3_k127_5178944_1 Protein of unknown function (DUF1572) - - - 0.000000000000000000000000000000002821 139.0
HFD3_k127_5178944_2 Hep Hag repeat protein - - - 0.000000000000000000000000001281 123.0
HFD3_k127_5178944_3 domain, Protein - - - 0.000000000000000000000002527 120.0
HFD3_k127_5194598_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 353.0
HFD3_k127_5194598_1 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006105 281.0
HFD3_k127_5194598_2 Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000000000128 153.0
HFD3_k127_5194598_3 Outer membrane lipoprotein K05807,K08309 - - 0.0000000000000000000000000002187 127.0
HFD3_k127_5194598_4 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000007288 128.0
HFD3_k127_5194598_5 gluconolactonase activity K01406,K14274,K20276,K21449 - 3.4.24.40 0.0000000008253 73.0
HFD3_k127_5194598_6 Glycosyl hydrolases family 35 K01190,K12308 - 3.2.1.23 0.00001884 48.0
HFD3_k127_5222876_0 Putative methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009597 500.0
HFD3_k127_5222876_1 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 335.0
HFD3_k127_5222876_2 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 306.0
HFD3_k127_5222876_3 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000001453 262.0
HFD3_k127_5222876_4 Regulates arginine biosynthesis genes K03402 - - 0.00000000000000000000000000000000000000000001629 175.0
HFD3_k127_5222876_5 Protein of unknown function (DUF861) - - - 0.0000000000000000000000000000000000006007 149.0
HFD3_k127_5235840_0 long-chain fatty acid transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000997 224.0
HFD3_k127_5235840_1 Protein of unknown function (DUF3179) - - - 0.0000000000000000000000009535 113.0
HFD3_k127_5235840_2 peptidylprolyl isomerase K03770 - 5.2.1.8 0.00000000009686 72.0
HFD3_k127_5251095_0 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000002207 249.0
HFD3_k127_5251095_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000005218 218.0
HFD3_k127_5251095_2 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000001266 208.0
HFD3_k127_5251095_3 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000006371 104.0
HFD3_k127_5251095_4 cheY-homologous receiver domain - - - 0.0000000000000000008978 89.0
HFD3_k127_5259232_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009117 591.0
HFD3_k127_5259232_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 562.0
HFD3_k127_5259232_10 Bacterial SH3 domain homologues - - - 0.000007993 53.0
HFD3_k127_5259232_2 Glycosyl transferases group 1 K00754 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009352 392.0
HFD3_k127_5259232_3 PFAM pyruvate phosphate dikinase, PEP pyruvate-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 379.0
HFD3_k127_5259232_4 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00973,K04042,K16881 - 2.3.1.157,2.7.7.13,2.7.7.23,2.7.7.24,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 338.0
HFD3_k127_5259232_5 Bacillithiol biosynthesis BshC K22136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000375 260.0
HFD3_k127_5259232_6 GlcNAc-PI de-N-acetylase K01463 - - 0.0000000000000000000000000000000000000000000000000000000000418 217.0
HFD3_k127_5259232_7 lysyltransferase activity K07027 - - 0.0000000000000000000000000000000000000000000000000001611 198.0
HFD3_k127_5259232_8 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000001982 181.0
HFD3_k127_5259232_9 Ami_3 K01448 - 3.5.1.28 0.00000000000000000004595 100.0
HFD3_k127_5264927_0 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 434.0
HFD3_k127_5264927_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 404.0
HFD3_k127_5265042_0 guanyl-nucleotide exchange factor activity - - - 0.000000000000000000000000000000000000000000000000005438 205.0
HFD3_k127_5265042_1 domain, Protein K20276 - - 0.00000000000000000000001586 117.0
HFD3_k127_5273934_0 UvrD REP helicase K03657,K07465 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000797 237.0
HFD3_k127_5277975_0 1-deoxy-D-xylulose-5-phosphate synthase activity K01662 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008654,GO:0008661,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0030976,GO:0032787,GO:0034641,GO:0036094,GO:0040007,GO:0042180,GO:0042181,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1901681 2.2.1.7 2.448e-202 649.0
HFD3_k127_5278410_0 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000901 203.0
HFD3_k127_5278410_1 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.00000000000000000000000001495 112.0
HFD3_k127_5278410_2 BMC - - - 0.00000000000000000000000001563 115.0
HFD3_k127_5278410_3 phosphoserine phosphatase activity K00058,K03567,K07166 - 1.1.1.399,1.1.1.95 0.0000000000000000000000009235 109.0
HFD3_k127_5278410_4 Acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000000000007118 67.0
HFD3_k127_5278410_5 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K00966,K16881 - 2.7.7.13,5.4.2.8 0.000000003503 60.0
HFD3_k127_5295027_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006,K01007 - 2.7.9.1,2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 499.0
HFD3_k127_5295027_1 acetyltransferase - - - 0.000000000000000000000000000004956 137.0
HFD3_k127_5295027_2 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000001112 67.0
HFD3_k127_5332359_0 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001614 250.0
HFD3_k127_5332359_1 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000003846 187.0
HFD3_k127_5332359_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000014 161.0
HFD3_k127_5340472_0 PFAM transposase IS116 IS110 IS902 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 296.0
HFD3_k127_5340472_1 Acetyltransferase (GNAT) domain K03824 - - 0.00000001928 65.0
HFD3_k127_5343799_0 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00004802 47.0
HFD3_k127_5357823_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 374.0
HFD3_k127_5357823_1 Methyltransferase domain - - - 0.00000000000000000000000000002736 122.0
HFD3_k127_5357823_2 Protein of unknown function (DUF1579) - - - 0.00000004357 60.0
HFD3_k127_5358927_0 Peptidase dimerisation domain K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006997 287.0
HFD3_k127_5358927_1 PFAM Peptidase M19, renal dipeptidase K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000001743 190.0
HFD3_k127_5358927_2 PFAM Metallopeptidase family M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000007412 60.0
HFD3_k127_5370414_0 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 337.0
HFD3_k127_5370414_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000005505 230.0
HFD3_k127_5370414_2 chain release factor K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.000000000000000000000000000000000000000000001745 168.0
HFD3_k127_5372963_0 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005696 251.0
HFD3_k127_5372963_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000001603 183.0
HFD3_k127_5372963_2 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000006704 110.0
HFD3_k127_5386468_0 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 423.0
HFD3_k127_5386468_1 Belongs to the carbamoyltransferase HypF family K04656 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007209 250.0
HFD3_k127_5386468_2 Hydrogenase maturation protease - - - 0.0000000000000000000000000009907 120.0
HFD3_k127_5386468_3 Hydrogenase/urease nickel incorporation, metallochaperone, hypA - - - 0.000000000000000002238 87.0
HFD3_k127_5388678_0 COGs COG1629 Outer membrane receptor protein mostly Fe transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008789 580.0
HFD3_k127_5388678_1 long-chain fatty acid transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 291.0
HFD3_k127_5388678_2 aminopeptidase N - - - 0.0000000000000000000000000000000000000000000000001939 200.0
HFD3_k127_5421307_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004773 407.0
HFD3_k127_5421307_1 Sugar isomerase (SIS) K15916 - 5.3.1.8,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 319.0
HFD3_k127_5421307_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 310.0
HFD3_k127_5421307_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002881 263.0
HFD3_k127_5421307_4 TIGRFAM DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000001456 198.0
HFD3_k127_5421307_5 DinB family - - - 0.000000000000000000022 94.0
HFD3_k127_5421307_6 PTS HPr component phosphorylation site K11189 - - 0.0000000000000000008849 89.0
HFD3_k127_5421307_7 DinB family - - - 0.0000000000001029 73.0
HFD3_k127_5431328_0 - Catabolite gene activator and regulatory subunit of cAMP-dependent protein K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 309.0
HFD3_k127_5431328_1 Roadblock/LC7 domain K07131 - - 0.0000000000000000000000000000000008997 134.0
HFD3_k127_5434127_0 amine dehydrogenase activity - - - 4.339e-235 758.0
HFD3_k127_5439752_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 2.553e-202 661.0
HFD3_k127_5439752_1 Plays a role in the flagellum-specific transport system K02419 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002882 278.0
HFD3_k127_5439752_2 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.0000000000000000000000000000000000000000000000000000000000000000001707 249.0
HFD3_k127_5439752_3 flagellar biosynthetic protein FliR K02421 - - 0.00000000000000000000000000000000000000004022 163.0
HFD3_k127_5439752_4 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02417 GO:0003674,GO:0003824,GO:0004721,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006935,GO:0008150,GO:0008152,GO:0009605,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0032879,GO:0036211,GO:0040011,GO:0040012,GO:0042221,GO:0042330,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051270,GO:0065007,GO:0071704,GO:0140096,GO:1901564,GO:1902021,GO:2000145 - 0.000000000000000000000000000000000001722 141.0
HFD3_k127_5439752_5 Role in flagellar biosynthesis K02420 - - 0.0000000000000000000001834 99.0
HFD3_k127_5439752_6 Flagellar biosynthesis K02404 - - 0.000000000000000001871 98.0
HFD3_k127_5439752_7 Belongs to the ParA family K04562 - - 0.00000000000000007174 89.0
HFD3_k127_5439752_8 flagellar K02418 - - 0.00002499 52.0
HFD3_k127_5451755_0 7TM receptor with intracellular HD hydrolase K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 397.0
HFD3_k127_5451755_1 PhoH-like protein K06217 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 362.0
HFD3_k127_5451755_2 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000001674 273.0
HFD3_k127_5451755_3 Transporter associated domain - - - 0.0000000000000000000000000000000000000000000000000000002318 210.0
HFD3_k127_5451755_4 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K07042 - 3.5.4.5 0.00000000000000000002188 102.0
HFD3_k127_5454780_0 beta-1,4-mannooligosaccharide phosphorylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 533.0
HFD3_k127_5454780_1 radical SAM domain protein K22318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 427.0
HFD3_k127_5472882_0 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 380.0
HFD3_k127_5472882_1 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000002424 201.0
HFD3_k127_5472882_2 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00004872 46.0
HFD3_k127_5477355_0 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002509 290.0
HFD3_k127_5477355_1 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000004003 181.0
HFD3_k127_5477355_2 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000000000000000000000001146 181.0
HFD3_k127_5477355_3 AAA domain - - - 0.00000000000000000000000000002172 131.0
HFD3_k127_5477355_4 Protein of unknown function (DUF3485) - - - 0.0000000000000000003278 102.0
HFD3_k127_547940_0 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 466.0
HFD3_k127_547940_1 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000552 263.0
HFD3_k127_547940_2 translation initiation factor activity - - - 0.0000000000000000000000000000000000000000000000000000000001591 211.0
HFD3_k127_547940_3 Mannose-6-phosphate isomerase K00971,K01840,K16011 - 2.7.7.13,5.3.1.8,5.4.2.8 0.000000000000000000000000000004634 121.0
HFD3_k127_547940_4 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104,K01808,K07566,K20201 - 2.7.7.87,3.1.3.48,3.9.1.2,5.3.1.6 0.000000000000000000000000000127 124.0
HFD3_k127_547940_5 Belongs to the SUA5 family K07566 GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.87 0.00000000000000000000000001327 118.0
HFD3_k127_5490326_0 lipopolysaccharide transport protein B ATP-binding component of ABC superfamily K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 330.0
HFD3_k127_5490326_1 PFAM peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009072 255.0
HFD3_k127_5490326_2 PFAM AMMECR1 domain protein K09141 - - 0.0000000000000000000000000000000000000000000000000007399 189.0
HFD3_k127_5490326_3 RNA polymerase sigma-54 factor K03092 - - 0.0000000000000000000000000000000001996 136.0
HFD3_k127_5490326_4 TIGRFAM DNA protecting protein DprA K04096 - - 0.00000000001382 75.0
HFD3_k127_5506687_0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 385.0
HFD3_k127_5506687_1 RNA polymerase sigma-54 factor K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 362.0
HFD3_k127_5506687_2 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000003424 199.0
HFD3_k127_5506687_3 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.0000005418 56.0
HFD3_k127_5508887_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 597.0
HFD3_k127_5508887_1 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000005327 130.0
HFD3_k127_5508887_2 extracellular matrix structural constituent - - - 0.000000000000003048 89.0
HFD3_k127_5516030_0 COG2346, Truncated hemoglobins K06886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006958 253.0
HFD3_k127_5516030_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000006453 239.0
HFD3_k127_5516030_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K03615,K05580 - 1.6.5.3 0.00000000000000000000000000000000000000000001071 169.0
HFD3_k127_5516030_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000001959 166.0
HFD3_k127_5516030_4 Berberine and berberine like - - - 0.00000000000000000000000002366 109.0
HFD3_k127_5539837_0 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008508 447.0
HFD3_k127_5539837_1 Domains in Na-Ca exchangers and integrin-beta4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 401.0
HFD3_k127_5539837_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000007737 96.0
HFD3_k127_5547713_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000008129 221.0
HFD3_k127_5547713_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000003873 154.0
HFD3_k127_5547713_2 amine dehydrogenase activity K21449 - - 0.0000000000000000000000000000000002012 139.0
HFD3_k127_5547713_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0001315 44.0
HFD3_k127_5548820_0 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000005876 153.0
HFD3_k127_5548820_1 Domain of unknown function (DUF4215) - - - 0.000000000000000000451 92.0
HFD3_k127_5548820_3 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000005608 80.0
HFD3_k127_5561239_0 Probable molybdopterin binding domain K03742,K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001798 296.0
HFD3_k127_5561239_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000000000000000000007405 201.0
HFD3_k127_5561239_2 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576 3.1.3.27 0.00000000000000000000000000009018 121.0
HFD3_k127_5561239_4 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000001255 62.0
HFD3_k127_5577355_0 oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor K00283 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019464,GO:0019752,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 367.0
HFD3_k127_5577355_1 - - - - 0.0000000000001393 83.0
HFD3_k127_5588003_0 NAD binding K00333,K13378 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 491.0
HFD3_k127_5588003_1 protein related to plant photosystem II stability assembly factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 479.0
HFD3_k127_5588003_2 PFAM Glyoxalase bleomycin resistance protein dioxygenase K07104 - 1.13.11.2 0.000000000000000000000000000000000000000000000000000000000000000003906 229.0
HFD3_k127_5588003_3 ThiS family K03636 - - 0.0000000000000000000175 94.0
HFD3_k127_5588003_4 ParE toxin of type II toxin-antitoxin system, parDE K19092 - - 0.0001393 44.0
HFD3_k127_5599190_0 Transglycosylase SLT domain K08307,K12204 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 452.0
HFD3_k127_5599190_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007002 361.0
HFD3_k127_5599190_2 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000665 268.0
HFD3_k127_5599190_3 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530,K05788 - - 0.00000000000000000000000000000000000004597 145.0
HFD3_k127_5599190_4 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000001416 138.0
HFD3_k127_5600434_0 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000000004846 205.0
HFD3_k127_5600434_1 Ethanolamine utilisation protein EutN/carboxysome K04028,K08697 - - 0.00000000000000002093 90.0
HFD3_k127_5600434_2 membrane - - - 0.00000000000002649 81.0
HFD3_k127_5600434_3 Ethanolamine utilisation protein EutN/carboxysome - - - 0.0000000004044 64.0
HFD3_k127_5600434_4 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.000000002196 67.0
HFD3_k127_5600434_5 - - - - 0.0000006522 62.0
HFD3_k127_5605147_0 Psort location CytoplasmicMembrane, score 9.49 K02003 - - 0.000000000000000000000000000000000000000000000005293 178.0
HFD3_k127_5605147_1 ERAP1-like C-terminal domain K01256,K01263 - 3.4.11.14,3.4.11.2 0.0000000000000000000000000000000000003276 148.0
HFD3_k127_5630558_0 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005188 544.0
HFD3_k127_56332_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 6.74e-231 729.0
HFD3_k127_56332_1 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 522.0
HFD3_k127_56332_2 ArgK protein K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001249 257.0
HFD3_k127_56332_3 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.0000000000000000000000000000000000000000000000000001657 187.0
HFD3_k127_56332_5 - - - - 0.000000005624 61.0
HFD3_k127_565034_0 Domain of unknown function (DUF4143) K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 400.0
HFD3_k127_565034_1 - - - - 0.000000000000000000000007347 108.0
HFD3_k127_5665614_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.889e-307 956.0
HFD3_k127_5671407_0 ABC-type transport system involved in lipoprotein release permease component K02004,K09808 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0098796,GO:0098797,GO:1990778 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001054 275.0
HFD3_k127_5671407_1 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000943 253.0
HFD3_k127_5671407_2 Catalyzes the specific phosphorylation of arginine residues in proteins K19405 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.000000000000000000000000000000000000000000000000000000000000005963 225.0
HFD3_k127_5671407_3 protein with conserved CXXC pairs K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 - 0.0000000000000000000000000000004061 129.0
HFD3_k127_5671797_0 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 385.0
HFD3_k127_5671797_1 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007412 289.0
HFD3_k127_5671797_2 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000008054 167.0
HFD3_k127_5671797_3 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.00000000000000000000000000000000000002054 157.0
HFD3_k127_567876_0 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009747 507.0
HFD3_k127_567876_1 Predicted Permease Membrane Region K07085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 409.0
HFD3_k127_567876_2 Ion channel - - - 0.0000000000000000000000000000000000000127 150.0
HFD3_k127_569040_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000002665 101.0
HFD3_k127_5707283_0 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000002234 185.0
HFD3_k127_5707283_2 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000003358 89.0
HFD3_k127_5739192_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 556.0
HFD3_k127_5739192_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K07305,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007469 424.0
HFD3_k127_5739192_2 PSP1, C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000005162 233.0
HFD3_k127_5739192_3 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000004607 220.0
HFD3_k127_5739192_4 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000003302 98.0
HFD3_k127_5739192_5 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.000000000000000000728 99.0
HFD3_k127_5739192_6 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.0006339 46.0
HFD3_k127_5777224_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 485.0
HFD3_k127_5777224_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007723 356.0
HFD3_k127_5777224_2 Belongs to the SEDS family K02563,K03588 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008360,GO:0009987,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032153,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051179,GO:0051234,GO:0051301,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000006812 259.0
HFD3_k127_5777224_3 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000318 235.0
HFD3_k127_5788474_0 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005362 278.0
HFD3_k127_5788474_1 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591,K13421 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10,4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000003213 233.0
HFD3_k127_579059_0 Surface antigen K07277 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 458.0
HFD3_k127_579059_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000006429 274.0
HFD3_k127_579059_2 Belongs to the skp family K06142 - - 0.000004882 55.0
HFD3_k127_5804490_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1261.0
HFD3_k127_5804490_1 aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000002952 217.0
HFD3_k127_5811330_0 PFAM Filamentation induced by cAMP death on - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 508.0
HFD3_k127_5811330_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - - 0.0000000000000000000000417 115.0
HFD3_k127_5811330_3 Domain of unknown function (DUF4124) - - - 0.000000006752 67.0
HFD3_k127_5811915_0 Propeptide_C25 - - - 0.00000000000000000000000000000000000000000000000000009463 198.0
HFD3_k127_5811915_1 Two component regulator propeller - - - 0.0000000000000000000000000000002193 141.0
HFD3_k127_5812095_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 612.0
HFD3_k127_5812095_1 Thioredoxin-like [2Fe-2S] ferredoxin K00334,K03388 - 1.6.5.3,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000001888 50.0
HFD3_k127_5813424_0 Histidine kinase K14986 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004493 291.0
HFD3_k127_5813424_1 Serine Threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000007522 146.0
HFD3_k127_5813424_2 membrane organization K07277 - - 0.00001909 53.0
HFD3_k127_5816092_0 PilX N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 581.0
HFD3_k127_5816092_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000102 181.0
HFD3_k127_5816092_2 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000004558 132.0
HFD3_k127_5816092_3 pilus assembly protein PilW K02672 - - 0.000000000000000149 87.0
HFD3_k127_5816092_4 NYN domain - - - 0.00000003027 64.0
HFD3_k127_5816092_5 Hep Hag repeat protein K01406 - 3.4.24.40 0.00001213 58.0
HFD3_k127_5822873_0 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006816 381.0
HFD3_k127_5822873_1 Methane oxygenase PmoA - - - 0.00000000000000000000000000000000000000000000000001338 204.0
HFD3_k127_5827125_0 PFAM Polysaccharide export protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 367.0
HFD3_k127_5827125_1 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000004171 143.0
HFD3_k127_5827125_2 Bacterial sugar transferase K00996 - 2.7.8.6 0.00000000000000000000000000008688 116.0
HFD3_k127_5828718_0 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002284 271.0
HFD3_k127_5828726_0 argininosuccinate lyase K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 507.0
HFD3_k127_5828726_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 377.0
HFD3_k127_5828726_2 Arginosuccinate synthase K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 361.0
HFD3_k127_5828726_3 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000000000000000000000000000000000000000002173 156.0
HFD3_k127_5828726_4 PFAM GCN5-related N-acetyltransferase K00619 - 2.3.1.1 0.00000000000000000000000000000126 131.0
HFD3_k127_5829433_0 COG3209 Rhs family protein - - - 0.00000000000000000000000000000000000000000004651 186.0
HFD3_k127_5830017_0 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 520.0
HFD3_k127_5830017_1 MmgE/PrpD family K01720 - 4.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 492.0
HFD3_k127_5830017_2 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 425.0
HFD3_k127_5830017_3 PFAM peptidase M24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 341.0
HFD3_k127_5830017_4 HEAT repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005477 268.0
HFD3_k127_5830017_5 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.000000000000000000000000000000000000000000000000000000000000000002975 229.0
HFD3_k127_5830017_6 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000001509 145.0
HFD3_k127_5830017_7 - - - - 0.0000000000000000000000000000001177 135.0
HFD3_k127_5830017_8 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000001799 118.0
HFD3_k127_5831980_0 Transcriptional regulator with HTH domain and aminotransferase domain containing protein K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006554 346.0
HFD3_k127_5831980_1 IMS family HHH motif K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 304.0
HFD3_k127_5831980_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000003324 225.0
HFD3_k127_5831980_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000004424 168.0
HFD3_k127_5852946_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005239 279.0
HFD3_k127_5852946_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000007115 214.0
HFD3_k127_5852946_2 phosphatase activity K07025,K20862 - 3.1.3.102,3.1.3.104 0.000000000000000000000000000000000001612 144.0
HFD3_k127_5852946_3 Ribosomal L32p protein family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.00000000000000000000004293 99.0
HFD3_k127_5852946_4 Uncharacterized ACR, COG1399 K07040 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000002893 102.0
HFD3_k127_5902364_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138,K18307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 434.0
HFD3_k127_5902364_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007976 332.0
HFD3_k127_5902364_2 exo-alpha-(2->6)-sialidase activity - - - 0.000000009535 66.0
HFD3_k127_5910096_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 482.0
HFD3_k127_5910096_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000005826 238.0
HFD3_k127_5910096_2 Transposase K07494 - - 0.000000000000001522 79.0
HFD3_k127_5922503_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000001299 160.0
HFD3_k127_5922503_1 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000001245 125.0
HFD3_k127_5922503_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000001369 95.0
HFD3_k127_5922503_3 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000001384 62.0
HFD3_k127_5965946_0 tRNA (Uracil-5-)-methyltransferase K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 362.0
HFD3_k127_5965946_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000005823 139.0
HFD3_k127_5973549_0 protein homotetramerization - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007102 260.0
HFD3_k127_5973549_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000006918 187.0
HFD3_k127_5973549_2 - - - - 0.0000000000000000000000000000000000000000000003036 173.0
HFD3_k127_5973549_4 glyoxalase III activity - - - 0.0000000000000000000000000000000000000004028 157.0
HFD3_k127_5973549_5 Acetyltransferase (GNAT) domain - - - 0.000000000000003831 81.0
HFD3_k127_5981387_0 Protein kinase domain K12132 - 2.7.11.1 1.581e-239 768.0
HFD3_k127_5981387_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009182 515.0
HFD3_k127_5981387_2 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000756 353.0
HFD3_k127_5981387_3 - - - - 0.0001261 49.0
HFD3_k127_5992503_0 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000395 264.0
HFD3_k127_6014116_0 carboxylic acid catabolic process K19802 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000007996 270.0
HFD3_k127_6014116_1 imidazolonepropionase activity - - - 0.0000000000000000000000000006105 114.0
HFD3_k127_6060591_0 Domain of unknown function (DUF1998) K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 1.072e-238 749.0
HFD3_k127_6063723_0 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 454.0
HFD3_k127_6063723_1 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000002183 203.0
HFD3_k127_6063723_2 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000001375 160.0
HFD3_k127_6063723_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000137 137.0
HFD3_k127_6063723_4 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000001255 110.0
HFD3_k127_6063723_5 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000005956 71.0
HFD3_k127_6090631_0 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000006381 181.0
HFD3_k127_6090631_1 NmrA-like family K00091 - 1.1.1.219 0.00000000000000000000000000000000004158 143.0
HFD3_k127_6090631_2 peptidyl-tyrosine sulfation - - - 0.0000000002456 70.0
HFD3_k127_6090631_3 response regulator, receiver - - - 0.0002462 50.0
HFD3_k127_6107968_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723,K05365 - 2.4.1.129,3.4.16.4 1.235e-224 719.0
HFD3_k127_6148669_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 - 1.4.1.2,1.4.1.3,1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009819 604.0
HFD3_k127_6148669_1 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000001489 176.0
HFD3_k127_6148669_2 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000005827 146.0
HFD3_k127_6148669_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 0.000000000000000000000000000000000001086 139.0
HFD3_k127_6148669_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000006175 123.0
HFD3_k127_6148669_5 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000004939 101.0
HFD3_k127_6154817_0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 481.0
HFD3_k127_6154817_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 314.0
HFD3_k127_6154817_2 Protein kinase domain K12132 - 2.7.11.1 0.000000000000009395 75.0
HFD3_k127_6164996_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 344.0
HFD3_k127_6164996_1 protein conserved in bacteria K02029,K02030,K09769 GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 297.0
HFD3_k127_6164996_2 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000005923 188.0
HFD3_k127_6164996_3 phosphatase activity K07025,K20862 - 3.1.3.102,3.1.3.104 0.000002443 50.0
HFD3_k127_6165882_0 Binding-protein-dependent transport system inner membrane component K02037,K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007744 529.0
HFD3_k127_6165882_1 phosphate ABC transporter K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 463.0
HFD3_k127_6165882_2 COG0226 ABC-type phosphate transport system periplasmic K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000919 434.0
HFD3_k127_6167997_0 Protein of unknown function (DUF1573) - - - 0.00000000000000000000000000008013 126.0
HFD3_k127_6167997_1 Protein of unknown function (DUF1573) - - - 0.000000000000000000001257 101.0
HFD3_k127_617547_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 5.804e-196 621.0
HFD3_k127_617547_1 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000008162 197.0
HFD3_k127_617547_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000002354 186.0
HFD3_k127_617547_3 Binds to the 23S rRNA K02876 - - 0.000001232 50.0
HFD3_k127_6192391_0 Two component, sigma54 specific, transcriptional regulator, Fis family K02667,K07713,K07714,K19641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005188 525.0
HFD3_k127_6192391_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000001307 109.0
HFD3_k127_6193664_0 Zn_pept - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 507.0
HFD3_k127_6193664_1 Periplasmic component of the Tol biopolymer transport system K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 416.0
HFD3_k127_6193664_2 - - - - 0.000000000000000000000000000000000000000000000000006728 190.0
HFD3_k127_6193664_3 Family of unknown function (DUF1028) - - - 0.00000000000000000000000000000000001133 153.0
HFD3_k127_6193664_4 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840 - 5.4.2.8 0.000000000000000000000000005161 114.0
HFD3_k127_6193664_5 exo-alpha-(2->6)-sialidase activity - - - 0.000000000009342 78.0
HFD3_k127_6193664_6 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000001642 58.0
HFD3_k127_6198007_0 - - - - 0.0000000001738 67.0
HFD3_k127_622279_0 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008846 587.0
HFD3_k127_622279_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000001352 237.0
HFD3_k127_622279_2 Polysaccharide biosynthesis C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000007201 236.0
HFD3_k127_622279_3 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000007768 169.0
HFD3_k127_622279_4 - - - - 0.00000000000000003465 89.0
HFD3_k127_626519_0 amine dehydrogenase activity K20276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007417 368.0
HFD3_k127_626519_2 alpha-L-arabinofuranosidase - - - 0.0000000004984 74.0
HFD3_k127_626519_3 exo-alpha-(2->6)-sialidase activity - - - 0.0000123 57.0
HFD3_k127_6270361_0 PFAM ABC transporter related K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 301.0
HFD3_k127_6270361_1 TIGRFAM N-terminal double-transmembrane domain - - - 0.0002259 52.0
HFD3_k127_628170_0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065,K13252 - 2.1.3.3,2.1.3.6,2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009766 313.0
HFD3_k127_6291230_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 533.0
HFD3_k127_6291230_1 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000001232 250.0
HFD3_k127_6291230_2 Polysaccharide lyase family 4, domain II - - - 0.0000000000000000000000000000000000000000000000000000000638 206.0
HFD3_k127_6291230_3 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000009297 206.0
HFD3_k127_6291230_4 - - - - 0.0000000000000000000000000000000000000000000000001896 189.0
HFD3_k127_6291230_5 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000371 188.0
HFD3_k127_6291230_6 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000725 149.0
HFD3_k127_6291230_7 TIGRFAM Caa(3)-type oxidase, subunit IV K02277 - 1.9.3.1 0.00002999 51.0
HFD3_k127_6313267_0 WD40 domain protein beta Propeller K12132 - 2.7.11.1 2.686e-230 742.0
HFD3_k127_6313267_1 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006033 279.0
HFD3_k127_6313267_2 coenzyme F390 K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000001205 240.0
HFD3_k127_6313267_3 Domain of unknown function (DUF4412) - - - 0.0000000000000000000000001763 118.0
HFD3_k127_6339511_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000898 358.0
HFD3_k127_634054_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 3.072e-306 949.0
HFD3_k127_634054_1 Sugar-specific transcriptional regulator TrmB - - - 0.000000000000000000000000000000000000000002839 166.0
HFD3_k127_6378973_1 - - - - 0.0000000000000000000000002445 114.0
HFD3_k127_6378973_2 NHL repeat containing protein - - - 0.000000000001216 76.0
HFD3_k127_6378973_3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000004708 74.0
HFD3_k127_6378973_4 Alpha/beta hydrolase family - - - 0.0000002698 61.0
HFD3_k127_6383932_0 metal-dependent phosphohydrolase HD region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008779 292.0
HFD3_k127_6383932_1 PFAM Peptidase family M50 - - - 0.000000000000000000000000000000000000000000796 165.0
HFD3_k127_6397240_0 PFAM ABC transporter K06020 - 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 594.0
HFD3_k127_6397240_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 370.0
HFD3_k127_6397240_2 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001455 288.0
HFD3_k127_6397240_3 Domain of unknown function (DUF4154) - - - 0.00000000000000000000000000007845 123.0
HFD3_k127_6397240_4 protein histidine kinase activity - - - 0.000000000007917 76.0
HFD3_k127_6420798_0 Belongs to the succinate malate CoA ligase beta subunit family K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 491.0
HFD3_k127_6420798_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703,K16792 - 4.2.1.114,4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 458.0
HFD3_k127_6420798_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 413.0
HFD3_k127_6420798_3 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007643 368.0
HFD3_k127_6420798_4 Belongs to the citrate synthase family K01647,K15234 - 2.3.3.1,4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001773 276.0
HFD3_k127_6420798_5 mRNA catabolic process K06950,K09163 - - 0.00000000000000000000000000000000000000000006024 166.0
HFD3_k127_6422123_0 Subtilase family - - - 5.567e-200 647.0
HFD3_k127_6426290_0 PFAM pyruvate carboxyltransferase K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 304.0
HFD3_k127_6426290_1 Biotin carboxylase C-terminal domain K01941,K11263 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 6.3.4.14,6.3.4.6,6.4.1.2,6.4.1.3 0.00000000000000000000000000000000616 134.0
HFD3_k127_6426290_2 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000000000001136 124.0
HFD3_k127_6426290_3 carboxylase K01968 - 6.4.1.4 0.0000000000003409 76.0
HFD3_k127_6441306_0 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001589 299.0
HFD3_k127_6460202_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1209.0
HFD3_k127_6460202_1 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 334.0
HFD3_k127_6460202_2 long-chain fatty acid transport protein - - - 0.00000000000008887 79.0
HFD3_k127_6471539_0 MutL protein K00854 - 2.7.1.17 1.562e-299 928.0
HFD3_k127_6471539_1 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 438.0
HFD3_k127_6471539_2 Phosphohydrolase-associated domain K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000121 295.0
HFD3_k127_6471539_3 Alg9-like mannosyltransferase family K05286 - - 0.00000000000000006177 87.0
HFD3_k127_6476711_0 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 396.0
HFD3_k127_6476711_1 Belongs to the ComB family K05979 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 0.0000000000000000000000000000000000000000000001131 177.0
HFD3_k127_6476711_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000001504 66.0
HFD3_k127_6519815_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 314.0
HFD3_k127_6519815_1 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 311.0
HFD3_k127_6519815_2 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000002325 206.0
HFD3_k127_6519815_3 2 iron, 2 sulfur cluster binding - - - 0.000000000000000000000000000000000005064 141.0
HFD3_k127_6523840_0 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 417.0
HFD3_k127_6523840_1 Immunoglobulin I-set domain protein K01179,K01406 - 3.2.1.4,3.4.24.40 0.0000000000000000000000002702 118.0
HFD3_k127_6525078_0 Belongs to the ABC transporter superfamily K10112 - - 0.00000000000000000000000000000000000000000000002423 177.0
HFD3_k127_6525078_1 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.00000000000000000000000000003514 134.0
HFD3_k127_6553937_0 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009412 339.0
HFD3_k127_6553937_1 Peptidase family M54 K06974 - - 0.00000000000000000000000000000000003892 144.0
HFD3_k127_6553937_2 phosphorelay signal transduction system K02481,K07713,K07714 - - 0.000000000000000000000000000000018 129.0
HFD3_k127_6553937_3 TIGRFAM conserved repeat domain protein - - - 0.0000000000000000000000000003914 134.0
HFD3_k127_6553937_4 YCII-related domain - - - 0.0000000000000000000000000226 111.0
HFD3_k127_6553937_6 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000005043 81.0
HFD3_k127_6553937_7 exo-alpha-(2->6)-sialidase activity - - - 0.000000000001928 79.0
HFD3_k127_6554261_0 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 587.0
HFD3_k127_6554261_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000009249 145.0
HFD3_k127_6554261_2 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000003221 128.0
HFD3_k127_6554261_3 COG NOG10142 non supervised orthologous group - - - 0.00000000000000000000000000003199 117.0
HFD3_k127_6555157_0 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 411.0
HFD3_k127_6555157_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 388.0
HFD3_k127_6555157_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000009322 176.0
HFD3_k127_6555157_3 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000001656 126.0
HFD3_k127_6555157_4 SpoVG K06412 - - 0.0000000000000000000001457 100.0
HFD3_k127_6569787_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006105 551.0
HFD3_k127_6569787_1 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000001822 173.0
HFD3_k127_6569787_2 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.00000000000006438 82.0
HFD3_k127_6574313_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 9.553e-296 917.0
HFD3_k127_6574313_1 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000001244 212.0
HFD3_k127_6574313_2 lipopolysaccharide metabolic process K07502,K08309,K19804,K21572 - - 0.00000000000000000000000000000000000000000000000000000002176 212.0
HFD3_k127_6574313_4 - - - - 0.0000000000000000000000005853 111.0
HFD3_k127_6577002_0 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 347.0
HFD3_k127_6577002_1 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 297.0
HFD3_k127_6577002_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000007029 234.0
HFD3_k127_6577002_3 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000000000000000000000000000000000000004352 230.0
HFD3_k127_6577002_4 - - - - 0.0000000002637 63.0
HFD3_k127_6583222_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 471.0
HFD3_k127_6583222_1 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.0000000000000000536 81.0
HFD3_k127_6591732_0 PFAM Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 317.0
HFD3_k127_6591732_1 PFAM Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000001321 279.0
HFD3_k127_6591732_2 Conserved protein of dim6 ntab family - - - 0.00000000000000000000000000000000000000000002736 173.0
HFD3_k127_6591732_3 amino acid - - - 0.00000000000000000000000000000000000000105 154.0
HFD3_k127_6612686_0 PKD domain K01179,K08651 - 3.2.1.4,3.4.21.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005795 405.0
HFD3_k127_6612686_1 PKD domain K01179,K08651 - 3.2.1.4,3.4.21.66 0.000000000000000000001202 108.0
HFD3_k127_6612686_2 exo-alpha-(2->6)-sialidase activity - - - 0.000000001448 70.0
HFD3_k127_6637499_0 COGs COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 376.0
HFD3_k127_6637499_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09697 - 3.6.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 293.0
HFD3_k127_6637499_2 ABC-2 family transporter protein K01992,K09696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001165 263.0
HFD3_k127_6637499_3 Peptidase M56 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006744 259.0
HFD3_k127_6637499_4 Peptidase M56 - - - 0.00000000000000000000000000000000000000000000000000000001127 218.0
HFD3_k127_6637499_5 Domain of unknown function (DUF4149) - - - 0.0000000002545 68.0
HFD3_k127_6639948_0 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 412.0
HFD3_k127_6639948_1 DNA-3-methyladenine glycosylase I K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000001135 228.0
HFD3_k127_6639948_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000005798 194.0
HFD3_k127_6639948_3 PFAM GCN5-related N-acetyltransferase - - - 0.00000000704 64.0
HFD3_k127_6643983_0 Type II IV secretion system protein K02454,K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003244 502.0
HFD3_k127_6643983_1 Type II secretory pathway component PulF K02505,K12278 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003336 282.0
HFD3_k127_6643983_2 adenosine deaminase K01488,K21053 - 3.5.4.2,3.5.4.4 0.000000000000000000000000000000000000000000004717 171.0
HFD3_k127_6643983_3 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.000000000000005607 89.0
HFD3_k127_6643983_4 Prokaryotic N-terminal methylation motif - - - 0.000000000001888 73.0
HFD3_k127_6643983_5 Type II secretion system (T2SS), protein G K02456 - - 0.000000003481 67.0
HFD3_k127_6643983_6 General secretion pathway protein K02456 - - 0.00001018 56.0
HFD3_k127_6644032_0 lysine 2,3-aminomutase K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 618.0
HFD3_k127_6644032_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007072 403.0
HFD3_k127_6644032_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 314.0
HFD3_k127_6644032_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000001562 170.0
HFD3_k127_6698868_0 Multicopper oxidase - - - 2.654e-220 707.0
HFD3_k127_6698868_1 Peptidase dimerisation domain K13049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 508.0
HFD3_k127_6698868_2 Prolyl oligopeptidase family K00433 - 1.11.1.10 0.000000000000000000000000000000000000000000000000000001503 194.0
HFD3_k127_6698868_3 AAA domain - - - 0.000000000000000000000000000000000000000000000001699 181.0
HFD3_k127_6724517_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0004470,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000001449 230.0
HFD3_k127_6724517_1 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000003914 196.0
HFD3_k127_6724517_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000001617 156.0
HFD3_k127_6724517_3 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000004466 153.0
HFD3_k127_6743270_0 HD domain K07023 - - 0.00000000000000000000000000000000000000004893 161.0
HFD3_k127_6747483_0 UvrD/REP helicase N-terminal domain K03656,K03657 GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 356.0
HFD3_k127_6747483_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007043 326.0
HFD3_k127_6789819_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000249 164.0
HFD3_k127_6789819_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000002249 146.0
HFD3_k127_679575_0 - - - - 0.000000000000000000000000000000000000000000001261 181.0
HFD3_k127_679575_1 membrane organization K21449 - - 0.00000000000000000000000000000000000000005638 172.0
HFD3_k127_679575_2 CarboxypepD_reg-like domain - - - 0.000003047 55.0
HFD3_k127_6797556_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000046 458.0
HFD3_k127_6797556_1 lipid A export permease ATP-binding protein MsbA K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 467.0
HFD3_k127_6797556_2 Glycosyl transferase family 2 K12984 - - 0.00000000000000000000000000000000000000000000000000000000003181 221.0
HFD3_k127_6797556_3 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843,K02849,K12982 - - 0.0000000000000000000000000003691 129.0
HFD3_k127_6797556_4 Peptidase family M50 K06402 - - 0.00000000002466 66.0
HFD3_k127_6802584_0 FeoA - - - 1.678e-300 938.0
HFD3_k127_6802584_1 PFAM Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006049 511.0
HFD3_k127_6802584_2 Beta-eliminating lyase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 436.0
HFD3_k127_6802584_3 Heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 302.0
HFD3_k127_6802584_4 iron ion homeostasis K03322,K03709,K04758 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005451 255.0
HFD3_k127_6802584_5 iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000000000000000000000000000008293 240.0
HFD3_k127_6802584_7 4Fe-4S dicluster domain K03389,K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000006062 203.0
HFD3_k127_6802584_8 protein secretion - - - 0.00000000000000000000000000000000000000001832 175.0
HFD3_k127_6802584_9 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000000000001398 89.0
HFD3_k127_6805833_0 carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 5.687e-252 786.0
HFD3_k127_6805833_1 COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit K01965,K01968 - 6.4.1.3,6.4.1.4 0.000000000000000000000000000000000000000000000000000000006112 207.0
HFD3_k127_6820024_0 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 439.0
HFD3_k127_6820024_1 Aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004755 320.0
HFD3_k127_6820024_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 304.0
HFD3_k127_6820024_3 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000004168 182.0
HFD3_k127_6820024_4 6-pyruvoyl tetrahydropterin synthase K01737 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0070497,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000513 166.0
HFD3_k127_6820024_5 4 iron, 4 sulfur cluster binding K05524 GO:0001666,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0009628,GO:0036293,GO:0043207,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0070482,GO:0075136 - 0.000000000000000000000000001839 115.0
HFD3_k127_6820024_6 transcriptional regulator K16137 - - 0.0000000000000000000000164 107.0
HFD3_k127_6820024_7 Transmembrane and tetratricopeptide repeat containing 4 - - - 0.0002803 54.0
HFD3_k127_6823807_0 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002028 287.0
HFD3_k127_6823807_1 protein serine/threonine phosphatase activity K01090,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000001734 184.0
HFD3_k127_6823807_2 Transglycosylase SLT domain K08307 - - 0.000000000000000000000000000001089 138.0
HFD3_k127_6823807_3 Protein of unknown function (DUF3467) - - - 0.000000000000000000000000000001305 125.0
HFD3_k127_6823807_4 protein containing a von Willebrand factor type A (vWA) domain - - - 0.000002493 59.0
HFD3_k127_6823807_5 PFAM PEGA domain - - - 0.000004466 60.0
HFD3_k127_6872470_0 PFAM transposase, IS4 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005678 305.0
HFD3_k127_6884478_0 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003322 332.0
HFD3_k127_6884478_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005454 306.0
HFD3_k127_6884478_2 ZIP Zinc transporter K07238,K16267 - - 0.00000000000000000000000000000000000000000000000000000002227 205.0
HFD3_k127_6884478_3 response regulator K03413,K07699 - - 0.0000000000000000000000000000000000006883 144.0
HFD3_k127_6884478_4 Regulatory protein, FmdB family - - - 0.000000000000000000000153 100.0
HFD3_k127_6885509_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K21025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 407.0
HFD3_k127_6885509_1 MlaD protein K02067 - - 0.000000000002002 70.0
HFD3_k127_68970_0 oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor K00311 GO:0003674,GO:0003824,GO:0004174,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016645,GO:0016649,GO:0016722,GO:0017133,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031304,GO:0031305,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032592,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043783,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045251,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070013,GO:0098573,GO:0098798,GO:1902494,GO:1990204 1.5.5.1 8.846e-219 694.0
HFD3_k127_68970_1 sister chromatid segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001161 280.0
HFD3_k127_68970_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000003774 243.0
HFD3_k127_68970_3 protein flavinylation K00380,K03734 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016740,GO:0017013,GO:0019538,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0031975,GO:0036094,GO:0036211,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0071944,GO:0071949,GO:0097159,GO:0098552,GO:0098567,GO:1901265,GO:1901363,GO:1901564 1.8.1.2,2.7.1.180 0.00000000000000000000000000000000000000000001658 181.0
HFD3_k127_68970_4 COG1278 Cold shock proteins K03704 - - 0.00000000000000000000000001596 109.0
HFD3_k127_68970_5 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000006085 99.0
HFD3_k127_68970_6 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000003281 97.0
HFD3_k127_68970_7 - - - - 0.00000000000001576 84.0
HFD3_k127_6900585_0 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000002916 168.0
HFD3_k127_6900585_1 Peptidase M56 - - - 0.000000000002653 79.0
HFD3_k127_6905104_0 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 316.0
HFD3_k127_6905104_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006002 269.0
HFD3_k127_6905104_10 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000002204 121.0
HFD3_k127_6905104_11 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000002631 108.0
HFD3_k127_6905104_12 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000001064 111.0
HFD3_k127_6905104_13 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000002582 112.0
HFD3_k127_6905104_14 rRNA binding K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000003706 105.0
HFD3_k127_6905104_15 Ribosomal L29 protein K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000008201 81.0
HFD3_k127_6905104_16 Ribosomal protein L30p/L7e K02907 - - 0.000000000000118 73.0
HFD3_k127_6905104_2 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000007604 249.0
HFD3_k127_6905104_3 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000009874 226.0
HFD3_k127_6905104_4 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000001727 216.0
HFD3_k127_6905104_5 Belongs to the universal ribosomal protein uS5 family K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000013 205.0
HFD3_k127_6905104_6 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000004459 199.0
HFD3_k127_6905104_7 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000000000001804 154.0
HFD3_k127_6905104_8 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000008742 142.0
HFD3_k127_6905104_9 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000001246 121.0
HFD3_k127_6906847_0 - - - - 0.000000000000000000000000000000000002935 154.0
HFD3_k127_6906847_1 Glycoside hydrolase family 24 - - - 0.00000000000000000000000000000000001925 157.0
HFD3_k127_6906847_2 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.0000000000000000227 90.0
HFD3_k127_6906847_3 Surface antigen - - - 0.0000000000000005355 93.0
HFD3_k127_6906847_4 NHL repeat containing protein - - - 0.000000000000005002 86.0
HFD3_k127_6906847_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000001933 80.0
HFD3_k127_6906847_6 - - - - 0.000000011 66.0
HFD3_k127_690924_0 Cytochrome C assembly protein K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003759 357.0
HFD3_k127_690924_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 5.4.99.12 0.0000000000000000000000000000000000000000000000000001836 194.0
HFD3_k127_690924_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000005552 94.0
HFD3_k127_6935072_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 2.232e-255 797.0
HFD3_k127_6935072_1 NHL repeat containing protein - - - 0.000000000005754 71.0
HFD3_k127_6946138_0 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000004373 250.0
HFD3_k127_6946138_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000004544 242.0
HFD3_k127_6946138_2 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000001123 211.0
HFD3_k127_6946138_3 NUDIX domain - - - 0.0000000000000000000000000000000000000007505 157.0
HFD3_k127_6946138_4 STAS domain K04749 - - 0.000000000000000000000000000000000000003372 148.0
HFD3_k127_6946138_5 Anti-sigma regulatory factor (Ser Thr protein kinase) K04757 - 2.7.11.1 0.000000000000000000000000000004871 124.0
HFD3_k127_6946138_6 surface antigen K07277,K07278 - - 0.0002029 53.0
HFD3_k127_6949926_0 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 360.0
HFD3_k127_6949926_1 glycosyl transferase K07011 - - 0.0000000000000000000000000000007707 132.0
HFD3_k127_6949926_2 Bacterial membrane protein YfhO - - - 0.0000000000000000000002696 109.0
HFD3_k127_6949926_3 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000002289 94.0
HFD3_k127_6987262_0 Immune inhibitor A peptidase M6 K09607 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001603 276.0
HFD3_k127_6987262_1 - - - - 0.0000000000000001244 93.0
HFD3_k127_6990717_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010556,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:1990837,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008028 394.0
HFD3_k127_6990717_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338,K03610 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003949 351.0
HFD3_k127_6992012_0 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006981 453.0
HFD3_k127_6992012_1 transport system permease K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 360.0
HFD3_k127_6992012_2 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006865 294.0
HFD3_k127_6992012_3 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008364 250.0
HFD3_k127_6992012_4 glyoxalase III activity - - - 0.0000000000000000000000000000000000000000000007772 178.0
HFD3_k127_6992012_5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000000000000000000000000000005746 181.0
HFD3_k127_6992012_6 maintenance of epithelial cell apical/basal polarity - - - 0.000000000000000000000000000000000001377 152.0
HFD3_k127_7005258_0 Glycosyltransferase Family 4 - - - 4.219e-280 867.0
HFD3_k127_7013884_0 Zn-dependent hydrolase K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008407 527.0
HFD3_k127_7013884_1 Aconitase C-terminal domain K01681 - 4.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 361.0
HFD3_k127_7013884_2 OmpA family - - - 0.000000000000000000000000003485 122.0
HFD3_k127_7013884_3 Transcriptional regulator, BadM Rrf2 family K13643 - - 0.00000000000000000000000002279 113.0
HFD3_k127_7023181_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 GO:0002682,GO:0002684,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006950,GO:0008150,GO:0009314,GO:0009380,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0032991,GO:0035821,GO:0042802,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004167 264.0
HFD3_k127_7025901_0 peptidase activity, acting on L-amino acid peptides K09607 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004998 345.0
HFD3_k127_7025901_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004378 258.0
HFD3_k127_7025901_2 cellulose binding - - - 0.000000000000000001251 91.0
HFD3_k127_7025901_3 PFAM FeoA family protein K04758 - - 0.0000000000001241 75.0
HFD3_k127_7046333_0 COGs COG3278 Cbb3-type cytochrome oxidase subunit 1 K00404,K15862 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 526.0
HFD3_k127_7046333_1 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 382.0
HFD3_k127_7046333_2 heavy metal translocating P-type ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002969 293.0
HFD3_k127_7046333_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000007356 242.0
HFD3_k127_7046333_4 PFAM cytochrome C oxidase mono-heme subunit FixO - - - 0.000000000000000000000000000000000000000000000000000000000000009997 223.0
HFD3_k127_7046333_5 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000001352 136.0
HFD3_k127_7046333_6 Acid phosphatase homologues - - - 0.0000000000000000000004874 104.0
HFD3_k127_7046333_7 - - - - 0.00000002266 63.0
HFD3_k127_7046333_8 PFAM blue (type 1) copper domain protein - - - 0.0000005469 62.0
HFD3_k127_7047437_0 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 293.0
HFD3_k127_7047437_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009233 284.0
HFD3_k127_7047437_2 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000001212 274.0
HFD3_k127_7047437_3 PFAM FAD dependent oxidoreductase K00303 - 1.5.3.1 0.0000000000000821 74.0
HFD3_k127_7047437_4 Winged helix-turn-helix domain (DUF2582) - - - 0.0000001507 59.0
HFD3_k127_7058287_0 Glycosyltransferase family 28 N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 454.0
HFD3_k127_7058287_1 auxin efflux carrier K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000633 346.0
HFD3_k127_7058287_10 Domain of unknown function (DUF1330) - - - 0.000000000000000002551 89.0
HFD3_k127_7058287_11 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000001533 76.0
HFD3_k127_7058287_2 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 312.0
HFD3_k127_7058287_3 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000000000000001703 199.0
HFD3_k127_7058287_4 - - - - 0.0000000000000000000000000000000000000000000000000004794 188.0
HFD3_k127_7058287_5 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000004565 203.0
HFD3_k127_7058287_6 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.000000000000000000000000000000000000000000000006547 183.0
HFD3_k127_7058287_7 Lactonase, 7-bladed beta-propeller K07004 - - 0.000000000000000000000000000000000000000000008428 171.0
HFD3_k127_7058287_8 - - - - 0.000000000000000000000000000000000000001045 151.0
HFD3_k127_7058287_9 PFAM DoxX family protein K15977 - - 0.0000000000000000000000000000001864 132.0
HFD3_k127_7063308_0 Phosphotransferase enzyme family - - - 0.0000000000000001065 93.0
HFD3_k127_7065447_0 Catalyzes the synthesis of GMP from XMP K01951,K03790 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.3.1.128,6.3.5.2 3.081e-197 629.0
HFD3_k127_7065447_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 497.0
HFD3_k127_7065447_2 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000007316 239.0
HFD3_k127_7065447_3 methyltransferase - - - 0.0000000000000000000000000000003471 132.0
HFD3_k127_7065447_4 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000001009 89.0
HFD3_k127_7067571_0 Fructose-bisphosphate aldolase class-I K01623 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007745 446.0
HFD3_k127_7067571_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000003351 127.0
HFD3_k127_7067571_2 Putative zinc-finger - - - 0.00001069 57.0
HFD3_k127_7085311_0 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000169 269.0
HFD3_k127_7085311_1 Electron transfer flavoprotein K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 0.000000000000000000000000000000000000000000000000000000000003027 212.0
HFD3_k127_7085311_2 cellulose binding - - - 0.000000000000000000000000000000000000000000433 181.0
HFD3_k127_7085311_3 PFAM Uncharacterised protein family (UPF0164) - - - 0.00000598 52.0
HFD3_k127_7087023_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 467.0
HFD3_k127_7087023_1 Involved in DNA repair and RecF pathway recombination K03584 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000001556 98.0
HFD3_k127_7111406_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 536.0
HFD3_k127_7111406_1 - - - - 0.00000000000000000000000001473 116.0
HFD3_k127_7111406_2 - - - - 0.0000008514 52.0
HFD3_k127_7120490_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 5.56e-227 715.0
HFD3_k127_7120490_1 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006546 397.0
HFD3_k127_7120490_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001632 271.0
HFD3_k127_7120490_3 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000009672 203.0
HFD3_k127_7120490_4 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) - - - 0.00000000000000000000000000000004628 127.0
HFD3_k127_7120490_5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000002233 80.0
HFD3_k127_7134522_0 Glucose / Sorbosone dehydrogenase - - - 0.00000003823 66.0
HFD3_k127_713724_0 Enoyl-CoA hydratase K07539,K18570 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000621 497.0
HFD3_k127_713724_1 S-(hydroxymethyl)glutathione dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 468.0
HFD3_k127_713724_10 domain containing protein K09553 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005794,GO:0005829,GO:0012505,GO:0031072,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051879,GO:0101031 - 0.0000415 51.0
HFD3_k127_713724_2 Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed K00626 GO:0003674,GO:0003824,GO:0003988,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 407.0
HFD3_k127_713724_3 reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000007833 233.0
HFD3_k127_713724_4 - - - - 0.00000000000000000000000000000000000000000000000000000001508 225.0
HFD3_k127_713724_5 Enoyl-CoA hydratase/isomerase K01715,K13767 GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 4.2.1.17 0.00000000000000000000000000000000000000000000000001647 191.0
HFD3_k127_713724_6 Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000449 181.0
HFD3_k127_713724_7 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000000000000002583 159.0
HFD3_k127_713724_8 Protein tyrosine kinase - - - 0.00000000000000000000000000000001946 134.0
HFD3_k127_7147632_0 4Fe-4S single cluster domain K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002305 287.0
HFD3_k127_7147632_1 Pyrroloquinoline quinone biosynthesis protein E - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001087 269.0
HFD3_k127_7147632_2 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.0000000000000000000000000000000000002818 143.0
HFD3_k127_7147632_3 PIN domain K07063 - - 0.00000000000000000000000000003538 121.0
HFD3_k127_7147632_4 PFAM Radical SAM superfamily - - - 0.00000000000000000009035 104.0
HFD3_k127_7147632_6 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.000000000000000001384 87.0
HFD3_k127_7147632_7 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00005216 52.0
HFD3_k127_7164699_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714,K21062 - 3.5.4.22,4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 371.0
HFD3_k127_7164699_1 ketoglutarate semialdehyde dehydrogenase K14519 - 1.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007733 325.0
HFD3_k127_7166172_0 regulation of RNA biosynthetic process K03705 GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000005822 261.0
HFD3_k127_7166172_1 unfolded protein binding K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0018995,GO:0019219,GO:0019222,GO:0020003,GO:0022607,GO:0030430,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0033643,GO:0033646,GO:0033655,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043531,GO:0043656,GO:0043657,GO:0043933,GO:0044085,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0065010,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000002654 225.0
HFD3_k127_7166172_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.000000000000000000000000000000000000000000000000000208 195.0
HFD3_k127_7166172_3 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000007711 127.0
HFD3_k127_7166172_4 Belongs to the multicopper oxidase YfiH RL5 family K05810 GO:0003674,GO:0005488,GO:0005507,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.000000000000000000000001371 116.0
HFD3_k127_7174037_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009756 459.0
HFD3_k127_7174037_1 Poly A polymerase head domain K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 365.0
HFD3_k127_7174037_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 308.0
HFD3_k127_7187061_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 3.495e-201 640.0
HFD3_k127_7187061_1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 351.0
HFD3_k127_7190078_0 ABC transporter transmembrane region K06147,K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 359.0
HFD3_k127_7194007_0 PFAM ABC transporter related K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 302.0
HFD3_k127_7194007_1 Exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.0000000000000000000000000000000000000000000000000000000001278 217.0
HFD3_k127_7194007_2 ABC-2 type transporter K09694 - - 0.0000000000000000000000000000000000000000000007489 185.0
HFD3_k127_7194007_3 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - - 0.00000000000000000000000000000000000000000001015 173.0
HFD3_k127_7263149_0 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 334.0
HFD3_k127_7263149_1 Oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001205 285.0
HFD3_k127_7266431_0 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 472.0
HFD3_k127_7266431_1 membrane K08988 - - 0.0000000000000000000001366 108.0
HFD3_k127_7266431_2 TPM domain K06872 - - 0.0000000000004374 74.0
HFD3_k127_7274842_0 DinB family - - - 0.0000000000000000000000000000000000000000000000000000000000000003014 228.0
HFD3_k127_7274842_1 - - - - 0.0000000000000000000000000000000000000000000000000002329 191.0
HFD3_k127_7274842_2 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000000000000000000000000000000000000002343 194.0
HFD3_k127_7274842_3 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000000000000000000000000000000176 174.0
HFD3_k127_7274842_4 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000000000000000003742 169.0
HFD3_k127_7294298_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 6.631e-300 944.0
HFD3_k127_7294298_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 350.0
HFD3_k127_7294298_2 TIGRFAM MazG family protein K02428,K02499 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000001184 260.0
HFD3_k127_7294298_3 Thrombospondin type 3 repeat - - - 0.000000000000000000000000000000000000004618 163.0
HFD3_k127_7294298_4 peptidyl-tyrosine sulfation - - - 0.000000009622 67.0
HFD3_k127_7294298_5 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000001308 60.0
HFD3_k127_7307819_0 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 369.0
HFD3_k127_7307819_1 Smr domain - - - 0.000000000000000000000009618 102.0
HFD3_k127_7339524_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 586.0
HFD3_k127_7339524_1 metalloendopeptidase activity K06013 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071586,GO:0071704,GO:0080120,GO:0140096,GO:1901564 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008217 287.0
HFD3_k127_7339524_2 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000001654 221.0
HFD3_k127_7339524_3 - - - - 0.0000000000000000001481 100.0
HFD3_k127_7339524_4 intracellular chloride channel activity - - - 0.000005221 56.0
HFD3_k127_7340370_0 Deoxyhypusine synthase K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 332.0
HFD3_k127_7340370_1 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005251 267.0
HFD3_k127_7340370_2 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000008636 259.0
HFD3_k127_7340370_3 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000009068 111.0
HFD3_k127_7348172_0 AI-2E family transporter - - - 0.000000000000000000000000000000000000002971 149.0
HFD3_k127_7348172_1 Belongs to the UPF0761 family K07058 - - 0.0000000000000000002545 100.0
HFD3_k127_7348172_2 long-chain fatty acid transporting porin activity - - - 0.00000000000002653 85.0
HFD3_k127_7348172_3 long-chain fatty acid transport protein - - - 0.00005216 52.0
HFD3_k127_7354118_0 Sodium:solute symporter family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 353.0
HFD3_k127_7354118_1 TonB-dependent receptor K02014 - - 0.00000000001248 77.0
HFD3_k127_7359494_0 ABC-type uncharacterized transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000093 291.0
HFD3_k127_7359494_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000003274 105.0
HFD3_k127_7359531_0 COGs COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 325.0
HFD3_k127_7359531_1 Phenazine biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 309.0
HFD3_k127_7359531_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000619 306.0
HFD3_k127_7359531_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008188 286.0
HFD3_k127_7359531_4 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009281 247.0
HFD3_k127_7359531_5 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000001218 234.0
HFD3_k127_7359531_6 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000206 171.0
HFD3_k127_7359531_7 - K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.000000000000000000000000000000000000000002684 163.0
HFD3_k127_7392565_0 - - - - 0.000000000000000000000000000000000000000000000000000000000001544 228.0
HFD3_k127_7392565_1 - - - - 0.00000000000009661 76.0
HFD3_k127_7392565_2 IMG reference gene - - - 0.0000001517 58.0
HFD3_k127_7404280_0 long-chain fatty acid transport protein - - - 0.0000000000000000000000000000000008478 147.0
HFD3_k127_7404280_2 protein trimerization K15368 - - 0.0000000000001983 79.0
HFD3_k127_7411907_0 Belongs to the pseudouridine synthase RsuA family K06178,K06181 - 5.4.99.20,5.4.99.22 0.00000000000000000000000000000000000000000000000000000007172 212.0
HFD3_k127_7411907_1 SpoU rRNA Methylase family - - - 0.000000000000000000000000000000000000000000000000003049 197.0
HFD3_k127_7411907_2 Amino acid permease - - - 0.000000000000000000000000000000000000001067 153.0
HFD3_k127_7411907_3 PFAM ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000000006109 153.0
HFD3_k127_7411907_4 Cysteine-rich secretory protein family - - - 0.0000000000000000000002275 109.0
HFD3_k127_7422166_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 488.0
HFD3_k127_7422166_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 334.0
HFD3_k127_7422166_2 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.00000000000000000000000000000000002914 143.0
HFD3_k127_7422166_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00004626 46.0
HFD3_k127_7427178_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 413.0
HFD3_k127_7427178_1 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 379.0
HFD3_k127_7427178_2 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859,K07566 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24,2.7.7.87 0.000000000000000000000000000000007169 134.0
HFD3_k127_7427178_3 Alpha beta K06889 - - 0.0000000000000000000000000002092 127.0
HFD3_k127_7427178_4 B3/4 domain - - - 0.0000000000000000007662 94.0
HFD3_k127_7427178_5 HAD-hyrolase-like K07025 - - 0.0000000000000000009074 94.0
HFD3_k127_7427178_6 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.000000000000000004361 85.0
HFD3_k127_7437671_0 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.00000000000000000000000000000976 127.0
HFD3_k127_7437671_1 molybdopterin K03750 - 2.10.1.1 0.000001283 53.0
HFD3_k127_7438964_0 tRNA processing K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000004452 232.0
HFD3_k127_7438964_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000003551 108.0
HFD3_k127_7442568_0 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000002707 193.0
HFD3_k127_7442568_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000002573 85.0
HFD3_k127_7442568_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000006483 55.0
HFD3_k127_7442568_4 Protein of unknown function, DUF481 K07283 - - 0.00004934 54.0
HFD3_k127_7442568_5 Anti-sigma factor - - - 0.0008796 48.0
HFD3_k127_7447926_0 Evidence 5 No homology to any previously reported sequences K17713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 369.0
HFD3_k127_7447926_1 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004431 327.0
HFD3_k127_7465815_0 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042221,GO:0042364,GO:0042398,GO:0042493,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000007242 250.0
HFD3_k127_7465815_1 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000657 218.0
HFD3_k127_7479672_0 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 529.0
HFD3_k127_7486249_0 Putative esterase - - - 0.00000000000000001659 93.0
HFD3_k127_7486249_1 extracellular matrix structural constituent - - - 0.00000000000000001761 98.0
HFD3_k127_7486249_2 exo-alpha-(2->6)-sialidase activity - - - 0.00000000002366 77.0
HFD3_k127_7486249_4 cellulase activity K18197 - 4.2.2.23 0.0002001 55.0
HFD3_k127_7495964_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 3.005e-198 629.0
HFD3_k127_7497650_0 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009819 383.0
HFD3_k127_7497650_1 Glycine cleavage H-protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006292 287.0
HFD3_k127_7497650_2 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003761 261.0
HFD3_k127_7497650_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.00000004805 58.0
HFD3_k127_751446_0 belongs to the aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007872 267.0
HFD3_k127_751446_1 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.0000000000000000000000000000000000000000000000000000000000000000000003161 273.0
HFD3_k127_7541376_0 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 512.0
HFD3_k127_7541376_1 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 421.0
HFD3_k127_7541376_2 Cytochrome c554 and c-prime K03620 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001567 290.0
HFD3_k127_7541376_3 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.000000000000000000000000000000000000000000001114 169.0
HFD3_k127_7541376_4 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000001591 150.0
HFD3_k127_7552597_0 O-acetylhomoserine K01740 - 2.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000486 460.0
HFD3_k127_7552597_1 Membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.00000000000000000000000000000004866 141.0
HFD3_k127_7552597_2 Helix-turn-helix diphteria tox regulatory element - - - 0.0000000000000000002057 94.0
HFD3_k127_7552597_3 PFAM SMP-30 Gluconolaconase - - - 0.0000000000001428 81.0
HFD3_k127_7552597_4 Putative esterase - - - 0.000004502 56.0
HFD3_k127_7577179_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 GO:0000027,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0022613,GO:0022618,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032794,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0043021,GO:0043022,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 424.0
HFD3_k127_7577179_1 Fe-S oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 333.0
HFD3_k127_7577179_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000004634 141.0
HFD3_k127_7577179_3 Glycerol-3-phosphate dehydrogenase K00057 GO:0003674,GO:0003824,GO:0006072,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.1.1.94 0.00000000000001258 78.0
HFD3_k127_7590890_0 Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate K00812,K14260 - 2.6.1.1,2.6.1.2,2.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 417.0
HFD3_k127_7590890_1 Domain of unknown function (DUF3473) - - - 0.000000000000000000000000000000000000000000000000000000004765 206.0
HFD3_k127_7590890_2 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000001018 205.0
HFD3_k127_7590890_3 metallopeptidase activity K06974 - - 0.0000000000000000000000000000000000000000000004078 172.0
HFD3_k127_7592470_0 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 333.0
HFD3_k127_7592470_1 GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000007059 242.0
HFD3_k127_7592470_2 ABC transporter K09812 - - 0.000000000000000000000000000000000000000002751 164.0
HFD3_k127_7592470_3 Peptidase, M23 K21471 - - 0.000000000000000000000000000000000000006426 165.0
HFD3_k127_7592470_4 MgtC SapB transporter K07507 - - 0.000000000000000000000000000000005045 135.0
HFD3_k127_7592470_5 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811 - - 0.0000000000000000000002646 107.0
HFD3_k127_7592470_6 ATP-dependent protease La (LON) substrate-binding domain K01338,K07157 - 3.4.21.53 0.00000000000000000003213 98.0
HFD3_k127_7614617_0 - - - - 5.394e-197 640.0
HFD3_k127_7619923_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1304.0
HFD3_k127_7619923_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 399.0
HFD3_k127_7658323_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 6.354e-237 766.0
HFD3_k127_7658323_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000002674 164.0
HFD3_k127_7697519_0 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006672 603.0
HFD3_k127_7697519_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000004719 145.0
HFD3_k127_7697519_2 Rhodanese Homology Domain - - - 0.000000000000000000000000000000001439 136.0
HFD3_k127_7697519_3 PFAM Methylamine utilisation protein MauE - - - 0.00000000000000000000000000001309 124.0
HFD3_k127_7697519_4 COG1525 Micrococcal nuclease (thermonuclease) homologs - - - 0.00000000000001303 83.0
HFD3_k127_7701737_1 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003357 244.0
HFD3_k127_7721292_0 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 490.0
HFD3_k127_7721292_1 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000016 281.0
HFD3_k127_7721292_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000008597 155.0
HFD3_k127_7721292_3 Arginosuccinate synthase K01940 - 6.3.4.5 0.00000000000000000000000000000000000000008794 154.0
HFD3_k127_7722789_0 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006974 382.0
HFD3_k127_7722789_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074,K12257 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 327.0
HFD3_k127_7722789_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 299.0
HFD3_k127_7722789_3 Domain of unknown function (DUF4159) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004914 273.0
HFD3_k127_7722789_4 Protein of unknown function (DUF2723) K16928 - - 0.000000000000000000000000000000000000000000000000000000000000001884 234.0
HFD3_k127_7722789_6 chaperone-mediated protein folding K20543 - - 0.000001809 61.0
HFD3_k127_7726860_0 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000001445 261.0
HFD3_k127_7726860_1 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000002658 225.0
HFD3_k127_7736937_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006479 507.0
HFD3_k127_7736937_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002333 233.0
HFD3_k127_778828_0 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000002769 224.0
HFD3_k127_778828_1 Polysaccharide biosynthesis export protein - - - 0.0000000000000000000000002244 122.0
HFD3_k127_778828_2 Thioredoxin-like - - - 0.00000000000000000003053 99.0
HFD3_k127_778828_3 Chain length determinant protein K01153,K05789,K07011,K16554 - 3.1.21.3 0.000000000000001017 84.0
HFD3_k127_784158_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005907 476.0
HFD3_k127_784158_1 Belongs to the ATCase OTCase family K00608,K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 428.0
HFD3_k127_784158_2 Belongs to the purine pyrimidine phosphoribosyltransferase family. PyrR subfamily K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000003089 196.0
HFD3_k127_784158_3 PspC domain - - - 0.000000000000000000008637 99.0
HFD3_k127_784158_4 membrane - - - 0.0000000000004199 80.0
HFD3_k127_784158_5 Scaffold protein Nfu/NifU N terminal - - - 0.0000000000004594 71.0
HFD3_k127_813066_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0040007,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 0.000000000000000000000000000000000000000000000000000003766 210.0
HFD3_k127_813066_1 GAF domain K02482 - 2.7.13.3 0.00003515 55.0
HFD3_k127_829638_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K16881 - 2.7.7.13,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 553.0
HFD3_k127_829638_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000001666 190.0
HFD3_k127_829638_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000002157 139.0
HFD3_k127_829638_3 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000959 139.0
HFD3_k127_835758_0 Domain of unknown function (DUF4153) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003616 253.0
HFD3_k127_835758_1 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006678 246.0
HFD3_k127_835758_2 Conserved protein containing a Zn-ribbon-like motif possibly RNA-binding - - - 0.000000000000000000000000000000000005087 145.0
HFD3_k127_835758_3 Domain of unknown function (DUF4136) - - - 0.000000000000000901 84.0
HFD3_k127_835758_5 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000004106 82.0
HFD3_k127_835758_6 Parallel beta-helix repeats - - - 0.00000000001174 78.0
HFD3_k127_84215_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005161 348.0
HFD3_k127_84215_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000001757 184.0
HFD3_k127_84215_3 integral membrane protein K02221 - - 0.000006732 54.0
HFD3_k127_84215_4 PFAM DivIVA family protein K04074 - - 0.0004688 46.0
HFD3_k127_864657_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850,K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007708 451.0
HFD3_k127_864657_1 extracellular matrix structural constituent - - - 0.000000000002927 68.0
HFD3_k127_882056_0 epimerase K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001284 278.0
HFD3_k127_882056_1 Protein of unknown function (DUF2867) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001026 266.0
HFD3_k127_882056_2 TspO/MBR family K05770 - - 0.0000000000000000000000000000000000000001634 158.0
HFD3_k127_894567_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008604 465.0
HFD3_k127_894567_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008555 305.0
HFD3_k127_894567_2 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000001066 228.0
HFD3_k127_894567_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000001467 209.0
HFD3_k127_894567_4 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000001315 162.0
HFD3_k127_894567_6 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000002585 79.0
HFD3_k127_910479_0 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000002717 200.0
HFD3_k127_910479_1 double-stranded DNA 3'-5' exodeoxyribonuclease activity K01142 - 3.1.11.2 0.0000000000000001002 91.0
HFD3_k127_910479_2 Membrane - - - 0.0009359 48.0
HFD3_k127_912775_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1386.0
HFD3_k127_912775_1 - - - - 0.00000000000000000000000000000000000000000000000000001083 204.0
HFD3_k127_912775_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000001751 190.0
HFD3_k127_915021_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 505.0
HFD3_k127_915021_1 Protein of unknown function (DUF2723) K16928 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 436.0
HFD3_k127_915021_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000001063 173.0
HFD3_k127_915021_3 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000003783 101.0
HFD3_k127_918661_0 phosphoglycerate kinase activity K00927,K01803 GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3,5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 465.0
HFD3_k127_918661_1 Subtilase family K13276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002002 306.0
HFD3_k127_918661_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000003311 266.0
HFD3_k127_918661_3 Preprotein translocase SecG subunit K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000000000000000002526 91.0
HFD3_k127_925082_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 352.0
HFD3_k127_925082_1 LVIVD repeat K01179 - 3.2.1.4 0.00000000000000000003717 105.0
HFD3_k127_947614_0 MafB19-like deaminase K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000002637 191.0
HFD3_k127_947614_3 receptor - - - 0.0007843 43.0
HFD3_k127_977492_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 3.795e-241 760.0
HFD3_k127_977492_1 tRNA synthetases class II (D, K and N) K01893 GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 593.0
HFD3_k127_977492_2 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 386.0
HFD3_k127_977492_3 Nodulation protein S (NodS) - - - 0.00000000000000000000001206 110.0
HFD3_k127_987549_0 COG1363 Cellulase M and related proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006496 383.0
HFD3_k127_987549_1 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 343.0
HFD3_k127_987549_10 aminopeptidase - - - 0.000000000000000000004523 98.0
HFD3_k127_987549_11 Cupin domain - - - 0.0000000000000000001677 93.0
HFD3_k127_987549_12 Tfp pilus assembly protein FimV - - - 0.000000000000000008692 95.0
HFD3_k127_987549_13 - - - - 0.0000000000000001725 86.0
HFD3_k127_987549_14 S-layer homology domain - - - 0.000000009881 68.0
HFD3_k127_987549_2 ABC 3 transport family K02075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007796 266.0
HFD3_k127_987549_3 Zinc-uptake complex component A periplasmic K02077 - - 0.0000000000000000000000000000000000000000000000000000000000005507 221.0
HFD3_k127_987549_4 response to oxidative stress K04063 - - 0.00000000000000000000000000000000000000000000000004667 183.0
HFD3_k127_987549_5 Protein of unknown function (DUF1428) - - - 0.000000000000000000000000000000000000000000000002011 176.0
HFD3_k127_987549_6 FR47-like protein - - - 0.00000000000000000000000000000000000000002104 158.0
HFD3_k127_987549_7 hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000005488 143.0
HFD3_k127_987549_9 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000009947 129.0