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Overview

ID MAG01700
Name HKD1_bin.10
Sample SMP0046
Taxonomy
Kingdom Bacteria
Phylum Myxococcota_A
Class UBA9160
Order UBA9160
Family SMWR01
Genus DASUFZ01
Species
Assembly information
Completeness (%) 72.3
Contamination (%) 1.02
GC content (%) 72.0
N50 (bp) 8,660
Genome size (bp) 3,561,626

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3287

Gene name Description KEGG GOs EC E-value Score Sequence
HKD1_k127_100070_0 transport system involved in gliding motility, auxiliary K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000575 289.0
HKD1_k127_100070_1 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000006822 263.0
HKD1_k127_100070_2 TatD related DNase K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000003818 218.0
HKD1_k127_100070_3 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000003944 154.0
HKD1_k127_100070_4 Domain of unknown function (DUF4340) - - - 0.0000000000000000000001083 113.0
HKD1_k127_1032363_0 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 321.0
HKD1_k127_1032363_1 Histidine-specific methyltransferase, SAM-dependent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004387 268.0
HKD1_k127_1032363_2 Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain - - - 0.00000000000000000000000000000000000000000000000000000000000000267 222.0
HKD1_k127_1032448_0 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 292.0
HKD1_k127_1032448_1 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000001034 240.0
HKD1_k127_1032448_2 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000001542 231.0
HKD1_k127_1032448_3 DNA ligase - - - 0.00000000000004615 84.0
HKD1_k127_1032448_4 DNA ligase K01971 - 6.5.1.1 0.0000000004159 72.0
HKD1_k127_106230_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005452 608.0
HKD1_k127_106230_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004151 503.0
HKD1_k127_106230_2 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 448.0
HKD1_k127_106230_3 ATPase with chaperone activity K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 435.0
HKD1_k127_106230_4 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 423.0
HKD1_k127_106230_5 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000001328 237.0
HKD1_k127_106230_6 - - - - 0.000000000000000000000006308 117.0
HKD1_k127_106230_7 Peptidase family M28 - - - 0.0005173 52.0
HKD1_k127_1063908_0 acetyl-CoA hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007392 503.0
HKD1_k127_1063908_1 Belongs to the TPP enzyme family K01652 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0019752,GO:0030312,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 525.0
HKD1_k127_1063908_10 PFAM Cupin - - - 0.000000000000000000000000000006989 121.0
HKD1_k127_1063908_11 response regulator, receiver - - - 0.0000000000000000000000001059 115.0
HKD1_k127_1063908_12 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000002419 119.0
HKD1_k127_1063908_13 Alanine-zipper, major outer membrane lipoprotein - - - 0.0007567 47.0
HKD1_k127_1063908_2 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 385.0
HKD1_k127_1063908_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 324.0
HKD1_k127_1063908_4 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 291.0
HKD1_k127_1063908_5 Cytochrome P450 K21200 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005593 280.0
HKD1_k127_1063908_6 L,D-transpeptidase catalytic domain K16291 - - 0.00000000000000000000000000000000000000000000000000000000009435 225.0
HKD1_k127_1063908_7 LysR substrate binding domain K03566 - - 0.0000000000000000000000000000000000000000000000000000000002753 214.0
HKD1_k127_1063908_8 PFAM aldo keto reductase K07079 - - 0.000000000000000000000000000000000000000000000000000000002842 224.0
HKD1_k127_1063908_9 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000001981 189.0
HKD1_k127_1067817_0 acetylesterase activity K14731 - 3.1.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000009707 261.0
HKD1_k127_1067817_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000002063 103.0
HKD1_k127_1090436_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 397.0
HKD1_k127_1090436_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003447 291.0
HKD1_k127_1090436_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000001031 248.0
HKD1_k127_1090436_3 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.0000000000000000000000000000000000000007135 153.0
HKD1_k127_1090436_4 hyperosmotic response - - - 0.00000000000000000000009994 106.0
HKD1_k127_1105431_0 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000004983 224.0
HKD1_k127_1105431_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000006907 205.0
HKD1_k127_1105431_2 PAC2 family - - - 0.00000000000000000000000000000000000000000000114 171.0
HKD1_k127_1120678_0 Glucose sorbosone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005809 359.0
HKD1_k127_1120678_1 acyl-CoA transferases carnitine dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 331.0
HKD1_k127_1120678_2 P-aminobenzoate N-oxygenase AurF - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 314.0
HKD1_k127_1120678_3 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 302.0
HKD1_k127_1120678_4 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009247 290.0
HKD1_k127_1120678_5 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000002678 102.0
HKD1_k127_1145297_0 sulfuric ester hydrolase activity K07014 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 553.0
HKD1_k127_1145297_1 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 354.0
HKD1_k127_1145297_2 containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000625 243.0
HKD1_k127_1145297_3 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0000000000000000000000000000000000000000000000000000000001722 210.0
HKD1_k127_1145297_4 hydrolase K07273 - - 0.0000000000000000000000000000000000000000000000000000000002266 211.0
HKD1_k127_1145297_5 Protein of unknown function (DUF1003) - - - 0.000000000000000001608 91.0
HKD1_k127_1145297_6 Protein of unknown function (DUF1003) - - - 0.00000000000008104 78.0
HKD1_k127_1145297_7 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000009856 85.0
HKD1_k127_1161223_0 ATPase components of ABC transporters with duplicated ATPase domains K06158 - - 3.597e-253 791.0
HKD1_k127_1161223_1 Major Facilitator Superfamily - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 524.0
HKD1_k127_1161223_2 Two component, sigma54 specific, transcriptional regulator, Fis family K07714,K19641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008067 462.0
HKD1_k127_1161223_3 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784,K12448 - 5.1.3.2,5.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009646 370.0
HKD1_k127_1161223_4 Enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005145 291.0
HKD1_k127_1161223_5 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.000000000000000000000000000000000000000001609 162.0
HKD1_k127_1161223_6 - - - - 0.0002771 51.0
HKD1_k127_1186366_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01907 - 6.2.1.1,6.2.1.16 9.262e-263 822.0
HKD1_k127_1186366_1 COG0474 Cation transport ATPase K01537 - 3.6.3.8 8.475e-260 829.0
HKD1_k127_1186366_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004153 446.0
HKD1_k127_1186366_3 TrkA-C domain K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008243 312.0
HKD1_k127_1186575_0 TIGRFAM Ammonium transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 431.0
HKD1_k127_1186575_1 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 388.0
HKD1_k127_1186575_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 382.0
HKD1_k127_1186575_3 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006715 299.0
HKD1_k127_1186575_4 glycosyl transferase group 1 K16703 - - 0.000000000000000000000000000000000000000000009944 186.0
HKD1_k127_1186575_5 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000003212 174.0
HKD1_k127_1192689_0 cytochrome p450 K16046 - 1.14.13.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001063 287.0
HKD1_k127_1192689_1 COG0518 GMP synthase - Glutamine amidotransferase domain K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000002628 280.0
HKD1_k127_1192689_2 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000002507 163.0
HKD1_k127_1192689_3 Multicopper oxidase - - - 0.00009946 53.0
HKD1_k127_1216613_0 Alpha beta hydrolase K01563 - 3.8.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005625 409.0
HKD1_k127_1216613_1 cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 401.0
HKD1_k127_1216613_2 Trehalose utilisation K09992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005344 267.0
HKD1_k127_1216613_3 dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003099 246.0
HKD1_k127_1218232_0 P-aminobenzoate N-oxygenase AurF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003386 269.0
HKD1_k127_1218232_1 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000009249 189.0
HKD1_k127_1218232_2 Probably functions as a manganese efflux pump - - - 0.00000000000000000000000000003932 136.0
HKD1_k127_1218232_3 transcriptional regulator K22107 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0042803,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000008068 106.0
HKD1_k127_1218232_4 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000003233 99.0
HKD1_k127_1218232_5 Divergent 4Fe-4S mono-cluster K05337 - - 0.0000000000000000001328 92.0
HKD1_k127_1218232_6 - - - - 0.0000000000000000005449 93.0
HKD1_k127_1218232_7 Tetratricopeptide repeat protein - - - 0.00000000000000000709 91.0
HKD1_k127_121929_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006556 574.0
HKD1_k127_121929_1 AAA domain (Cdc48 subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 383.0
HKD1_k127_121929_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 385.0
HKD1_k127_121929_3 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 357.0
HKD1_k127_121929_4 VWA domain containing CoxE-like protein K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004396 310.0
HKD1_k127_121929_5 TIGRFAM methylmalonyl-CoA mutase N-terminal domain K01847,K01848 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000004328 264.0
HKD1_k127_121929_6 TIGRFAM methylmalonyl-CoA mutase N-terminal domain K01847,K01848 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000007956 222.0
HKD1_k127_121929_7 Small GTP-binding protein K06883 - - 0.000000000000000000000000000000000000000000000000000000000006527 222.0
HKD1_k127_1224307_1 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 396.0
HKD1_k127_122807_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 373.0
HKD1_k127_122807_1 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000001233 227.0
HKD1_k127_122807_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000001771 49.0
HKD1_k127_122807_3 Bacterial regulatory protein, Fis family - - - 0.00003759 52.0
HKD1_k127_122807_4 OmpA-like transmembrane domain K16079 - - 0.00009355 52.0
HKD1_k127_1228448_0 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 404.0
HKD1_k127_1228448_1 SnoaL-like domain - - - 0.0000000000000000000000000000000000003731 145.0
HKD1_k127_1228448_2 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000004915 135.0
HKD1_k127_1228448_3 Haemolysin-III related K11068 - - 0.000000000000000000000003188 111.0
HKD1_k127_1228448_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000008078 97.0
HKD1_k127_1228448_5 COG0076 Glutamate decarboxylase and related PLP-dependent proteins K01634 - 4.1.2.27 0.000000000002534 68.0
HKD1_k127_1228448_6 DNA-binding protein, H-NS K03746 - - 0.000000926 55.0
HKD1_k127_1228448_7 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.00006465 48.0
HKD1_k127_1262428_0 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007924 271.0
HKD1_k127_1262428_1 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000002733 237.0
HKD1_k127_1262428_2 phosphatase K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000004377 180.0
HKD1_k127_1262428_3 pyridoxamine 5'-phosphate - - - 0.0000000000000000000000000000000000000005288 164.0
HKD1_k127_1262428_4 Uncharacterized conserved protein (DUF2277) - - - 0.000000000000000000000000000000000758 132.0
HKD1_k127_1271350_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006579 328.0
HKD1_k127_1271350_1 Receptor K02014 - - 0.00000000000000000000000004879 124.0
HKD1_k127_1271350_2 oligosaccharyl transferase activity - - - 0.000000005298 70.0
HKD1_k127_1271350_3 Domain of unknown function (DUF4136) - - - 0.00000193 57.0
HKD1_k127_1271350_4 - - - - 0.00001681 48.0
HKD1_k127_1284060_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 426.0
HKD1_k127_1284060_1 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 402.0
HKD1_k127_1284060_2 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000000004461 149.0
HKD1_k127_1284060_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000003867 100.0
HKD1_k127_1284060_4 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.00000000000005452 85.0
HKD1_k127_1284060_5 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000001027 65.0
HKD1_k127_1284060_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.00007326 55.0
HKD1_k127_1310735_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 8.485e-281 889.0
HKD1_k127_1310735_1 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009768 581.0
HKD1_k127_1310735_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 391.0
HKD1_k127_1323457_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 547.0
HKD1_k127_1323457_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 486.0
HKD1_k127_1323457_10 Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000000153 83.0
HKD1_k127_1323457_11 peptidyl-tyrosine sulfation - - - 0.000000003226 62.0
HKD1_k127_1323457_12 - - - - 0.00000006267 67.0
HKD1_k127_1323457_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 356.0
HKD1_k127_1323457_3 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000141 195.0
HKD1_k127_1323457_4 repeat protein - - - 0.00000000000000000000000000000000000000000001316 188.0
HKD1_k127_1323457_5 transport system involved in gliding motility, auxiliary K01992 - - 0.00000000000000000000000000002815 133.0
HKD1_k127_1323457_6 PFAM MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000003269 128.0
HKD1_k127_1323457_7 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.00000000000000000001765 107.0
HKD1_k127_1323457_8 peptidyl-tyrosine sulfation - - - 0.00000000000000000005747 99.0
HKD1_k127_1323457_9 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000005639 85.0
HKD1_k127_1343632_0 Aldehyde dehydrogenase family K22445 - 1.2.99.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 515.0
HKD1_k127_1343632_1 Mate efflux family protein K03327 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006857,GO:0006862,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015215,GO:0015230,GO:0015605,GO:0015711,GO:0015748,GO:0015833,GO:0015931,GO:0015932,GO:0016020,GO:0022857,GO:0034220,GO:0035350,GO:0035442,GO:0035672,GO:0035673,GO:0042886,GO:0042887,GO:0042938,GO:0044464,GO:0044610,GO:0051179,GO:0051181,GO:0051182,GO:0051184,GO:0051185,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071916,GO:0071944,GO:0098656,GO:1901264,GO:1901505,GO:1901679,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 330.0
HKD1_k127_1343632_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001068 279.0
HKD1_k127_1343632_3 ABC1 family K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000008856 260.0
HKD1_k127_1343632_4 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.00000000000000000000000000000007278 130.0
HKD1_k127_1343632_5 - - - - 0.0000000000000000009058 88.0
HKD1_k127_1343632_6 PFAM UspA - - - 0.0000000000001376 85.0
HKD1_k127_1343632_7 - - - - 0.000000005757 63.0
HKD1_k127_1343632_8 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.0001531 53.0
HKD1_k127_1353389_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 321.0
HKD1_k127_1353389_1 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.0000000000000000000000000000000000000000003313 166.0
HKD1_k127_1353389_2 PFAM peptidase S49 K04773,K04774 - - 0.000000000000000000000000000000000000000001196 166.0
HKD1_k127_1353389_3 Lysin motif K08307 - - 0.000000000000000000000000000000000000002065 158.0
HKD1_k127_1353389_4 catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.00000000000000000000000003997 123.0
HKD1_k127_1356494_0 Response regulator receiver modulated diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008186 577.0
HKD1_k127_1356494_1 histidine kinase HAMP region domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 490.0
HKD1_k127_1356494_2 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000004818 156.0
HKD1_k127_137962_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 527.0
HKD1_k127_137962_1 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002046 292.0
HKD1_k127_137962_10 thiolester hydrolase activity K06889 - - 0.00000000004172 73.0
HKD1_k127_137962_11 Belongs to the ParA family K04562 - - 0.00000003586 64.0
HKD1_k127_137962_2 2-phosphoglycerate kinase K05715 - - 0.0000000000000000000000000000000000000000000000000000000000000000001954 244.0
HKD1_k127_137962_3 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000000000222 223.0
HKD1_k127_137962_4 translation initiation factor activity K03496,K09000 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000007034 194.0
HKD1_k127_137962_5 Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - - - 0.000000000000000000000000000000000001766 149.0
HKD1_k127_137962_6 signal peptide peptidase SppA, 36K type K04773,K04774 - - 0.00000000000000000000000000002201 137.0
HKD1_k127_137962_7 protein secretion K03116 - - 0.00000000000000007657 83.0
HKD1_k127_137962_8 Tetratricopeptide repeat - - - 0.000000000000004092 81.0
HKD1_k127_137962_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000005704 80.0
HKD1_k127_1385023_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 444.0
HKD1_k127_1385023_1 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 362.0
HKD1_k127_1385023_2 Hydroxymethylglutaryl-CoA lyase K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 321.0
HKD1_k127_1385023_3 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006009 315.0
HKD1_k127_1385023_4 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004923 296.0
HKD1_k127_1385023_5 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000002072 168.0
HKD1_k127_1385023_6 PFAM ribonuclease BN K07058 - - 0.00000000001421 71.0
HKD1_k127_1385023_7 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - - 0.0005324 51.0
HKD1_k127_1410836_0 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002088 254.0
HKD1_k127_1410836_1 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000327 245.0
HKD1_k127_1410836_2 PFAM ABC transporter K09817 - - 0.00000000000000000000000000000000000000000000000003979 193.0
HKD1_k127_1410836_3 ABC-type Mn2 Zn2 transport systems permease components K02075,K09816 - - 0.000000000000000000000000000000000000003494 168.0
HKD1_k127_1410836_4 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases - - - 0.000000000000000000000000000000001319 135.0
HKD1_k127_1410836_5 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000001343 142.0
HKD1_k127_1410836_6 Zinc-uptake complex component A periplasmic K09815 - - 0.00000000000000000000000000000005172 131.0
HKD1_k127_1411091_0 Protein of unknown function (DUF455) K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000003339 206.0
HKD1_k127_1462417_0 RimK-like ATPgrasp N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 559.0
HKD1_k127_1462417_1 PFAM Glutamate-cysteine ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 478.0
HKD1_k127_1462417_2 Glutathione S-transferase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007452 411.0
HKD1_k127_1462417_3 Aminotransferase class I and II K14155 - 4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 353.0
HKD1_k127_1462417_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009281 263.0
HKD1_k127_1462417_5 N-formylglutamate amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000001868 206.0
HKD1_k127_1462417_6 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 0.000001052 51.0
HKD1_k127_1465177_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138,K18307 - - 7.306e-264 876.0
HKD1_k127_1465177_1 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 432.0
HKD1_k127_1465177_10 Belongs to the acetyltransferase family. ArgA subfamily K00537,K00619 - 1.20.4.1,2.3.1.1 0.0000000000000000000000000000000000000002878 164.0
HKD1_k127_1465177_11 Phytanoyl-CoA dioxygenase (PhyH) K10674 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016705,GO:0016706,GO:0019752,GO:0032787,GO:0042399,GO:0042400,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0051213,GO:0055114,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.14.11.55 0.00000000000000000000000000000000105 141.0
HKD1_k127_1465177_12 Cytochrome c K12263 - - 0.00000000000000004322 93.0
HKD1_k127_1465177_13 - - - - 0.0000000000000008214 91.0
HKD1_k127_1465177_14 transcriptional regulator K13770 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000003116 85.0
HKD1_k127_1465177_2 fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 336.0
HKD1_k127_1465177_3 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 316.0
HKD1_k127_1465177_4 haloacid dehalogenase-like hydrolase K02203 - 2.7.1.39,3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000452 285.0
HKD1_k127_1465177_5 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000001458 244.0
HKD1_k127_1465177_6 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000007046 224.0
HKD1_k127_1465177_7 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000005327 224.0
HKD1_k127_1465177_8 Tetratricopeptide repeat protein - - - 0.000000000000000000000000000000000000000000000000000005119 207.0
HKD1_k127_1465177_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000005804 186.0
HKD1_k127_146648_0 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 332.0
HKD1_k127_146648_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 327.0
HKD1_k127_146648_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000001656 229.0
HKD1_k127_146648_3 PFAM FMN-binding domain protein - - - 0.000000000000000000000000000000000000000000000009139 189.0
HKD1_k127_146648_4 dna ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000009131 170.0
HKD1_k127_146648_5 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000005032 156.0
HKD1_k127_146648_6 - - - - 0.000000000000000000000000000000002942 135.0
HKD1_k127_1469177_0 Acyl-CoA dehydrogenase, type 2, C-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 447.0
HKD1_k127_1469177_1 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002315 295.0
HKD1_k127_1469177_2 acyl-CoA dehydrogenase K00249,K07545 - 1.3.8.3,1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000006866 220.0
HKD1_k127_1469177_3 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000001567 163.0
HKD1_k127_1487842_0 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005956 308.0
HKD1_k127_1487842_1 SMART Tetratricopeptide domain protein - - - 0.00000006659 65.0
HKD1_k127_1501730_0 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000473 581.0
HKD1_k127_1501730_1 Ring hydroxylating alpha subunit (catalytic domain) K00499 - 1.14.15.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000003029 271.0
HKD1_k127_1501730_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000004651 216.0
HKD1_k127_1501730_3 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000000000000002413 229.0
HKD1_k127_1501730_4 cytochrome p450 K16046 - 1.14.13.221 0.00000000000000002158 87.0
HKD1_k127_1501730_5 PFAM Colicin V production protein K03558 - - 0.00004764 52.0
HKD1_k127_1502734_0 enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 329.0
HKD1_k127_1502734_1 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000008967 176.0
HKD1_k127_1502734_2 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.000000000000000000000000000002094 127.0
HKD1_k127_1502734_3 ErfK YbiS YcfS YnhG K16291 - - 0.00000005271 65.0
HKD1_k127_1502734_4 Tetratricopeptide repeat - - - 0.0005006 52.0
HKD1_k127_1507524_0 CHAT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 538.0
HKD1_k127_1507524_1 Belongs to the amidase family K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 400.0
HKD1_k127_1510334_0 COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes K00164 - 1.2.4.2 2.349e-291 922.0
HKD1_k127_1510334_1 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 452.0
HKD1_k127_1510334_2 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003835 394.0
HKD1_k127_1510334_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 376.0
HKD1_k127_1510334_4 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 343.0
HKD1_k127_1510334_5 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 345.0
HKD1_k127_1510334_6 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000000000001839 227.0
HKD1_k127_1510334_7 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000007899 194.0
HKD1_k127_1510334_8 Alpha beta hydrolase - - - 0.000000000000000000000004418 115.0
HKD1_k127_1510334_9 TIGRFAM Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily - - - 0.00000000000000001743 91.0
HKD1_k127_152592_0 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 297.0
HKD1_k127_152592_1 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000001536 248.0
HKD1_k127_152592_2 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.0000000000000000000000000000000000000001373 157.0
HKD1_k127_152592_3 methyltransferase activity - - - 0.00000000000000000000000000000000000003266 149.0
HKD1_k127_152592_4 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000002053 144.0
HKD1_k127_152592_5 Glutathione S-transferase, C-terminal domain - - - 0.00000000000000000000000000000000004886 147.0
HKD1_k127_152592_6 YCII-related domain K09780 - - 0.000000000000000000000000004667 113.0
HKD1_k127_152592_7 Sulfotransferase family - - - 0.00000000000000000000006848 114.0
HKD1_k127_152592_8 Alpha/beta hydrolase family K01046 - 3.1.1.3 0.00000000000000000005004 104.0
HKD1_k127_152592_9 Phosphoesterase K07095 - - 0.00000000000000001388 97.0
HKD1_k127_1528693_0 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004647 336.0
HKD1_k127_153670_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 411.0
HKD1_k127_153670_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 376.0
HKD1_k127_153670_2 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000006429 258.0
HKD1_k127_153670_3 TIGRFAM signal peptidase I K03100 - 3.4.21.89 0.00000000000000000000000000000000000000001862 163.0
HKD1_k127_153670_4 elongation factor SelB, winged helix K03833 - - 0.0000000000003462 72.0
HKD1_k127_1587607_0 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000003504 237.0
HKD1_k127_1587607_1 Acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000006176 217.0
HKD1_k127_1587607_2 TraB family K09973 - - 0.00000000000000000000000000000000001423 151.0
HKD1_k127_1587607_3 Patatin-like phospholipase K07001 - - 0.000000000000000000238 94.0
HKD1_k127_1587607_4 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.000000000000008629 89.0
HKD1_k127_1587607_5 Chromosome Partitioning K03496 - - 0.000005492 49.0
HKD1_k127_1589646_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 489.0
HKD1_k127_1589646_1 Domain of unknown function (DUF4131) K02238 - - 0.00000000000000000000002892 114.0
HKD1_k127_1607845_0 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 318.0
HKD1_k127_1607845_1 PFAM Protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000001205 183.0
HKD1_k127_1607845_2 repeat protein - - - 0.0000000000000002289 94.0
HKD1_k127_1607845_3 protein kinase activity - - - 0.0000004324 63.0
HKD1_k127_1607845_4 PilZ domain - - - 0.00003095 57.0
HKD1_k127_1625071_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007865 509.0
HKD1_k127_1625071_1 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009135 467.0
HKD1_k127_1625071_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 400.0
HKD1_k127_1625071_3 SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006395 312.0
HKD1_k127_1625071_4 PFAM Membrane protein of K08972 - - 0.000000000000000000000000000001402 126.0
HKD1_k127_1625071_5 Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000005695 115.0
HKD1_k127_1625071_6 hydrolase (HAD superfamily) - - - 0.00000000000001072 83.0
HKD1_k127_1684215_0 Glycosyl transferase family 21 K03669 - - 3.451e-203 682.0
HKD1_k127_1684215_1 Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) K03670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 543.0
HKD1_k127_1684215_2 META domain - - - 0.00000000000000000000000000000000000000007377 160.0
HKD1_k127_1704865_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 320.0
HKD1_k127_1704865_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000336 263.0
HKD1_k127_1704865_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000001666 261.0
HKD1_k127_1704865_3 Response regulator receiver domain K03413 - - 0.00000000000000000000000000000000000000000001528 178.0
HKD1_k127_1704865_4 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000001546 89.0
HKD1_k127_1704865_5 Lipopolysaccharide-assembly - - - 0.00000002241 62.0
HKD1_k127_174305_0 PFAM Carbamoyl-phosphate synthase L chain ATP-binding K01955 - 6.3.5.5 2.414e-286 896.0
HKD1_k127_174305_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 497.0
HKD1_k127_174305_2 COG0183 Acetyl-CoA acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008317 363.0
HKD1_k127_174305_3 - - - - 0.0000000000000000000000000000000000000000000000000000000007596 212.0
HKD1_k127_1762338_0 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007442 262.0
HKD1_k127_1762338_1 Bacterial protein of unknown function (DUF898) - - - 0.0000000000000000000000000000000000000000000000000000000000001767 225.0
HKD1_k127_1762338_2 PFAM Alpha beta hydrolase fold-3 domain protein K14731 - 3.1.1.83 0.0000000000000000000000000000000000000000000000000000000004827 218.0
HKD1_k127_1762338_3 COG0501 Zn-dependent protease with chaperone function - - - 0.000000000000000000000000000000000000000000000000133 200.0
HKD1_k127_1823669_0 Aldehyde dehydrogenase family - - - 5.215e-202 646.0
HKD1_k127_1823669_1 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 372.0
HKD1_k127_1823669_2 Belongs to the bacterial glucokinase family - - - 0.00000000000000000000000000000000000001649 151.0
HKD1_k127_1823669_3 Polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000000000003226 135.0
HKD1_k127_1823669_4 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000005956 97.0
HKD1_k127_1823669_5 C-type lectin (CTL) or carbohydrate-recognition domain (CRD) - - - 0.000000000000002664 90.0
HKD1_k127_1846008_0 Enoyl-CoA hydratase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 297.0
HKD1_k127_1846008_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000009583 269.0
HKD1_k127_1846008_2 Glutathione S-transferase N-terminal domain K00799 - 2.5.1.18 0.00000000002162 73.0
HKD1_k127_1857485_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.065e-230 746.0
HKD1_k127_1857485_1 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001338 244.0
HKD1_k127_1857485_2 Sterol carrier protein - - - 0.00005419 51.0
HKD1_k127_187925_0 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003209 262.0
HKD1_k127_187925_1 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000176 225.0
HKD1_k127_187925_2 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.0000000000000000000000000000000000000000000988 174.0
HKD1_k127_187925_3 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.0000000000000000000000000000000000007806 156.0
HKD1_k127_187925_4 KR domain - - - 0.0000000000000000000000000000000004636 147.0
HKD1_k127_1886254_0 Flavin-binding monooxygenase-like K07222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005105 343.0
HKD1_k127_1886254_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000003678 209.0
HKD1_k127_1886254_2 Transcriptional regulator - - - 0.00006425 55.0
HKD1_k127_1900416_0 Acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001386 301.0
HKD1_k127_1900416_1 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003222 283.0
HKD1_k127_1900416_2 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006090,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019184,GO:0019752,GO:0031974,GO:0032787,GO:0034641,GO:0042398,GO:0043043,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0051186,GO:0051188,GO:0070013,GO:0071704,GO:1901564,GO:1901566,GO:1901576 3.1.2.6 0.0000000000000000000000000000000000000000000000002691 191.0
HKD1_k127_1900416_3 Alpha/beta hydrolase family K07020 - - 0.0000000000000000000000000000000001135 142.0
HKD1_k127_1900416_4 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000004592 114.0
HKD1_k127_1903013_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K18687 - 6.2.1.41 4.176e-218 688.0
HKD1_k127_1903013_1 belongs to the aldehyde dehydrogenase family K22445 - 1.2.99.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 550.0
HKD1_k127_1903013_2 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005267 544.0
HKD1_k127_1903013_3 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 517.0
HKD1_k127_1903013_4 FAD dependent oxidoreductase K13796 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008652 449.0
HKD1_k127_1903013_5 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003375 451.0
HKD1_k127_1903013_6 KR domain K00059 GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008554 339.0
HKD1_k127_1903013_7 COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase K01082 - 3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 320.0
HKD1_k127_1903013_8 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000004716 228.0
HKD1_k127_1903013_9 Bacterial transcriptional repressor C-terminal - - - 0.000000000000000000000000000000000000000009483 161.0
HKD1_k127_190408_0 Phosphoketolase K01621 - 4.1.2.22,4.1.2.9 9.361e-200 625.0
HKD1_k127_190408_1 F5/8 type C domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006449 570.0
HKD1_k127_1908921_0 lytic transglycosylase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007824 386.0
HKD1_k127_1908921_1 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 337.0
HKD1_k127_1908921_2 cytochrome p450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 326.0
HKD1_k127_1908921_3 Transcriptional regulatory protein, C terminal K07665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 314.0
HKD1_k127_1908921_4 Membrane protein, TerC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005582 287.0
HKD1_k127_1908921_5 Member of a two-component regulatory system K02484 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002289 286.0
HKD1_k127_1908921_6 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000003169 194.0
HKD1_k127_1908921_7 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.000000000000000000000000002242 113.0
HKD1_k127_1922276_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 3.508e-204 666.0
HKD1_k127_1922276_1 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000001066 220.0
HKD1_k127_1922276_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 0.000000000006285 74.0
HKD1_k127_1922276_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000001996 60.0
HKD1_k127_1924058_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004377 392.0
HKD1_k127_1924058_1 Alanine-glyoxylate amino-transferase K00375 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 306.0
HKD1_k127_1924058_2 Belongs to the PdxS SNZ family K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000003817 264.0
HKD1_k127_1924058_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000003852 169.0
HKD1_k127_1924058_4 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000002645 168.0
HKD1_k127_1932112_0 UvrD/REP helicase N-terminal domain - - - 6.684e-194 646.0
HKD1_k127_1932112_1 exonuclease activity K16899 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 575.0
HKD1_k127_19329_0 PFAM aspartate glutamate uridylate kinase K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 485.0
HKD1_k127_19329_1 PFAM ribonuclease BN K07058 - - 0.0000000000000000000000000000000003533 152.0
HKD1_k127_19329_2 Threonylcarbamoyl adenosine biosynthesis protein TsaE K07102 - 2.7.1.221 0.0001958 47.0
HKD1_k127_1937070_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 451.0
HKD1_k127_1937070_1 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000002479 146.0
HKD1_k127_1937070_2 thiolester hydrolase activity - - - 0.0000000000000000000007105 109.0
HKD1_k127_1937070_3 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000005875 96.0
HKD1_k127_1972109_0 PQQ enzyme repeat - - - 4.604e-251 790.0
HKD1_k127_1972109_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 329.0
HKD1_k127_1972109_10 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000000000001692 130.0
HKD1_k127_1972109_11 acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000001163 108.0
HKD1_k127_1972109_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 330.0
HKD1_k127_1972109_3 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 336.0
HKD1_k127_1972109_4 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 309.0
HKD1_k127_1972109_5 KR domain K05296 - 1.1.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000005107 273.0
HKD1_k127_1972109_6 - - - - 0.00000000000000000000000000000000000000000000000000000001055 228.0
HKD1_k127_1972109_7 Crp-like helix-turn-helix domain K10914 - - 0.000000000000000000000000000000000000000000000000005523 190.0
HKD1_k127_1972109_8 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000001664 177.0
HKD1_k127_1972109_9 - - - - 0.0000000000000000000000000000000000000000003081 170.0
HKD1_k127_199409_0 Dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009893 342.0
HKD1_k127_199409_1 repeat protein - - - 0.00000261 58.0
HKD1_k127_199409_2 Domain of unknown function (DUF4388) - - - 0.00000271 59.0
HKD1_k127_199409_3 histone H2A K63-linked ubiquitination - - - 0.00005327 53.0
HKD1_k127_2023486_0 Belongs to the aldehyde dehydrogenase family K00128,K06447 - 1.2.1.3,1.2.1.71 2.484e-239 747.0
HKD1_k127_2023486_1 PFAM tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 1.366e-198 628.0
HKD1_k127_2031703_0 PFAM FAD linked oxidase domain protein K00803 - 2.5.1.26 2.543e-206 671.0
HKD1_k127_2031703_1 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 521.0
HKD1_k127_2031703_2 F420-dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 300.0
HKD1_k127_2031703_3 Transposase zinc-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000729 205.0
HKD1_k127_2031703_4 methionine sulfoxide reductase K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000007234 194.0
HKD1_k127_2031703_5 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0006215 51.0
HKD1_k127_2055568_0 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 323.0
HKD1_k127_2055568_1 Belongs to the pseudouridine synthase RsuA family K06178,K06181 - 5.4.99.20,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000004651 229.0
HKD1_k127_2055568_2 SMART ABC-type transporter, periplasmic subunit family 3, ionotropic glutamate receptor K02030 - - 0.00000000000000000000000000000000000000000000000000000000009373 218.0
HKD1_k127_2055568_3 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000003487 215.0
HKD1_k127_2055568_4 - - - - 0.00000000000000000000000000000000000000000000002429 182.0
HKD1_k127_2060999_0 PFAM Alcohol dehydrogenase zinc-binding domain protein K07119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005029 403.0
HKD1_k127_2060999_1 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009442 340.0
HKD1_k127_2060999_2 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 334.0
HKD1_k127_2060999_3 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001545 280.0
HKD1_k127_2060999_4 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001691 269.0
HKD1_k127_2060999_5 UDP-glucoronosyl and UDP-glucosyl transferase K16444 - 2.4.1.310 0.00000000000000000000000000000000000000002161 164.0
HKD1_k127_2060999_6 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000003648 154.0
HKD1_k127_2060999_7 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000002149 98.0
HKD1_k127_2067718_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000000000000000000007683 222.0
HKD1_k127_2067718_2 aminopeptidase activity - - - 0.0000000000000000000000000000000003674 153.0
HKD1_k127_2067718_3 Transglutaminase-like superfamily - - - 0.000000000000000000001038 107.0
HKD1_k127_2067718_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000009501 83.0
HKD1_k127_2073338_0 PFAM Protein synthesis factor, GTP-binding K06207 - - 1.634e-201 643.0
HKD1_k127_2073338_1 PFAM Di-heme cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000005679 221.0
HKD1_k127_2073338_2 Methyltransferase FkbM domain - - - 0.00000000000000002108 95.0
HKD1_k127_2090502_0 taurine catabolism dioxygenase K03119,K22303 - 1.14.11.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 323.0
HKD1_k127_2090502_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002139 287.0
HKD1_k127_2090502_2 Alpha beta hydrolase K14731 - 3.1.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001632 282.0
HKD1_k127_2090502_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000005331 237.0
HKD1_k127_2092541_0 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 419.0
HKD1_k127_2092541_1 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007911 282.0
HKD1_k127_2092541_2 PFAM ATP-binding region - - - 0.00000000000000000000000000000000000000000000000792 194.0
HKD1_k127_210326_0 PFAM phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 382.0
HKD1_k127_210326_1 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001578 293.0
HKD1_k127_210326_2 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000001234 239.0
HKD1_k127_210326_3 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000003185 180.0
HKD1_k127_210326_4 PFAM Cytochrome C assembly protein K02195 - - 0.00000000000000000000000000000000000000000003307 169.0
HKD1_k127_211330_0 SMART Tetratricopeptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 315.0
HKD1_k127_211330_1 Tetratricopeptide repeat - - - 0.00003751 56.0
HKD1_k127_2113644_0 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000001362 179.0
HKD1_k127_2113644_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000001347 158.0
HKD1_k127_2113644_2 HemY protein K02498 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000398 62.0
HKD1_k127_2161966_0 SMART AAA ATPase K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005533 350.0
HKD1_k127_217154_0 Bacterial regulatory protein, Fis family K02481,K07713,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 418.0
HKD1_k127_217154_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 313.0
HKD1_k127_217154_2 NADH pyrophosphatase-like rudimentary NUDIX domain K03426 - 3.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000007119 270.0
HKD1_k127_217154_3 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000001885 247.0
HKD1_k127_217154_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000001196 207.0
HKD1_k127_217154_5 mttA/Hcf106 family K03116,K03117 - - 0.0000000000007038 72.0
HKD1_k127_217154_6 His Kinase A (phosphoacceptor) domain - - - 0.0000000000009648 82.0
HKD1_k127_217154_7 Sigma-54 interaction domain K19641 - - 0.000000000245 74.0
HKD1_k127_217154_8 repeat-containing protein - - - 0.0000001452 63.0
HKD1_k127_2171726_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409,K03070 GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.0000000000000000000000000000000000000000000000000000004974 199.0
HKD1_k127_2171726_1 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000000000000000000000000000001713 174.0
HKD1_k127_2171726_2 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000001605 119.0
HKD1_k127_2171726_3 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000004591 81.0
HKD1_k127_2244651_0 Uncharacterized protein conserved in bacteria (DUF2332) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000153 293.0
HKD1_k127_2244651_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000001341 185.0
HKD1_k127_2244651_2 Protein of unknown function (DUF3313) - - - 0.000004523 57.0
HKD1_k127_2244651_3 light absorption - - - 0.00013 51.0
HKD1_k127_2244651_4 PDZ domain K01173,K14949 - 2.7.11.1 0.0001795 53.0
HKD1_k127_2244651_5 Peptidase family M23 K21472 - - 0.0005938 52.0
HKD1_k127_224843_0 TIGRFAM ABC exporter ATP-binding subunit, DevA family K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000176 240.0
HKD1_k127_224843_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000005902 192.0
HKD1_k127_224843_2 - - - - 0.000000000000000000000000000000000000009119 163.0
HKD1_k127_2260182_0 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.000000000000000000000000000000000000115 147.0
HKD1_k127_2260182_1 CBS domain K04767,K07168,K07182 - - 0.00000000000000000000000000000007593 138.0
HKD1_k127_2271035_0 Cytochrome P450 K05525,K20497 - 1.14.13.151,1.14.15.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 387.0
HKD1_k127_2271035_1 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 304.0
HKD1_k127_2271035_2 TIGRFAM YihY family protein (not ribonuclease BN) K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008143 265.0
HKD1_k127_2271035_3 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006876 255.0
HKD1_k127_2271035_4 Domain of unknown function (DUF4142) K08995 - - 0.00000000000000000000000008616 117.0
HKD1_k127_2271035_5 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0000004574 60.0
HKD1_k127_2279587_0 Acetyl-CoA acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000001893 253.0
HKD1_k127_2279587_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000000000000002462 201.0
HKD1_k127_2279587_2 Polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000000000000000007886 105.0
HKD1_k127_2287192_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 625.0
HKD1_k127_2287192_1 aminotransferase K14261 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 522.0
HKD1_k127_2287192_2 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 450.0
HKD1_k127_2287192_3 Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 446.0
HKD1_k127_2287192_4 PFAM 2-nitropropane dioxygenase NPD K00459,K02371 - 1.13.12.16,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 379.0
HKD1_k127_2287192_5 glycosyl hydrolase 38 domain protein K01191 - 3.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000792 351.0
HKD1_k127_2287192_6 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000738 295.0
HKD1_k127_2287192_7 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001956 289.0
HKD1_k127_2287192_8 riboflavin synthase alpha K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000004611 203.0
HKD1_k127_2287192_9 oligosaccharyl transferase activity - - - 0.0000000001045 76.0
HKD1_k127_2295204_0 PFAM Alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 588.0
HKD1_k127_2295204_1 - - - - 0.00000000000000000000000000000000000000000000000000000000001016 213.0
HKD1_k127_2295204_2 - - - - 0.000000000000000000000000000000000000000000000195 180.0
HKD1_k127_2295204_3 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000001354 175.0
HKD1_k127_2295204_4 - - - - 0.0000000000000000000000000000000000000000001169 167.0
HKD1_k127_2295204_5 Gram-negative-bacterium-type cell outer membrane assembly K04064,K06186 GO:0006950,GO:0006970,GO:0008150,GO:0009628,GO:0050896 - 0.000000000000000000000000000000000002862 139.0
HKD1_k127_2295204_6 protoporphyrinogen oxidase activity K01854,K07011 - 5.4.99.9 0.00008218 50.0
HKD1_k127_230060_0 metal-dependent hydrolase of the TIM-barrel fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 485.0
HKD1_k127_230060_1 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 308.0
HKD1_k127_230060_2 Acetoacetate decarboxylase (ADC) K01574 - 4.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000001938 258.0
HKD1_k127_230060_3 KR domain - - - 0.0000000000000000000000000000000000006447 145.0
HKD1_k127_230060_4 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000275 122.0
HKD1_k127_230060_5 Universal stress protein family - - - 0.0000000000001194 75.0
HKD1_k127_230060_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000002534 60.0
HKD1_k127_230060_7 repeat-containing protein - - - 0.000127 52.0
HKD1_k127_2308877_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 5.903e-194 627.0
HKD1_k127_2308877_1 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 613.0
HKD1_k127_2308877_2 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008659 585.0
HKD1_k127_2308877_3 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749,K18313 - 2.8.3.16,2.8.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 537.0
HKD1_k127_2308877_4 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 388.0
HKD1_k127_2308877_5 beta-keto acid cleavage enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 303.0
HKD1_k127_2308877_6 - - - - 0.000000000000000000000000007191 126.0
HKD1_k127_2308877_7 Putative MetA-pathway of phenol degradation - - - 0.00000000000000000000000001598 122.0
HKD1_k127_2308877_8 Protein of unknown function (DUF2905) - - - 0.0000000000003425 82.0
HKD1_k127_231466_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008460,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 477.0
HKD1_k127_231466_1 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 467.0
HKD1_k127_231466_2 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000002005 278.0
HKD1_k127_234262_0 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008715 327.0
HKD1_k127_234262_1 Phospholipid N-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000005478 222.0
HKD1_k127_234262_2 transcriptional regulator - - - 0.000000000000000004091 91.0
HKD1_k127_234262_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K14161 - - 0.000000003114 61.0
HKD1_k127_2354629_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 5.581e-219 692.0
HKD1_k127_2354629_1 F5/8 type C domain - - - 0.0000000000000000000000000001012 119.0
HKD1_k127_2358366_0 Aldo Keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 425.0
HKD1_k127_2358366_1 Belongs to the aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008879 417.0
HKD1_k127_2358366_10 - - - - 0.0000000000000000000000000000000000000008464 160.0
HKD1_k127_2358366_11 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000001209 165.0
HKD1_k127_2358366_12 IMP dehydrogenase activity K04767 - - 0.000000000000000000000000000001882 130.0
HKD1_k127_2358366_13 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000004487 107.0
HKD1_k127_2358366_14 Domain of unknown function (DUF4345) - - - 0.00000000005294 68.0
HKD1_k127_2358366_15 - - - - 0.00000003731 65.0
HKD1_k127_2358366_2 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 284.0
HKD1_k127_2358366_3 thiolester hydrolase activity K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000003647 246.0
HKD1_k127_2358366_4 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000001444 204.0
HKD1_k127_2358366_5 LysE type translocator - GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015318,GO:0015711,GO:0015804,GO:0015807,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0042968,GO:0042970,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000001308 183.0
HKD1_k127_2358366_6 PFAM OsmC family protein - - - 0.0000000000000000000000000000000000000000000000004293 194.0
HKD1_k127_2358366_7 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000006235 174.0
HKD1_k127_2358366_8 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000001627 170.0
HKD1_k127_2358366_9 YhhN family - - - 0.00000000000000000000000000000000000000001747 164.0
HKD1_k127_2361546_0 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 644.0
HKD1_k127_2361546_1 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006103 577.0
HKD1_k127_2361546_10 nucleotide catabolic process - - - 0.00000000000000007589 95.0
HKD1_k127_2361546_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 417.0
HKD1_k127_2361546_3 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 314.0
HKD1_k127_2361546_4 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.0000000000000000000000000000000000000000000000006005 188.0
HKD1_k127_2361546_5 TIGRFAM Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.00000000000000000000000000000000000000004059 175.0
HKD1_k127_2361546_6 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000009505 149.0
HKD1_k127_2361546_7 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000001539 149.0
HKD1_k127_2361546_8 heat shock protein binding - - - 0.00000000000000000002022 97.0
HKD1_k127_2361546_9 Cytochrome c554 and c-prime - - - 0.00000000000000000002411 107.0
HKD1_k127_2372873_0 COG2015 Alkyl sulfatase and related hydrolases - - - 6.849e-219 699.0
HKD1_k127_2372873_1 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 559.0
HKD1_k127_2372873_2 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 314.0
HKD1_k127_2372873_3 Glutathione S-transferase, C-terminal domain K00799,K03599 - 2.5.1.18 0.0000000000000000000000000000003765 132.0
HKD1_k127_2396042_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 519.0
HKD1_k127_2396042_1 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005042 318.0
HKD1_k127_2396042_2 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.0000000000000000000000000000000001854 144.0
HKD1_k127_2401277_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 8.4e-322 998.0
HKD1_k127_2401277_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005728 568.0
HKD1_k127_2401277_2 Protein of unknown function (DUF3641) - - - 0.00000000000000000000000000000000000000000000000000000000000000003711 227.0
HKD1_k127_2401277_3 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000001073 201.0
HKD1_k127_2401277_4 AAA domain - - - 0.00000000000000000000000000000000000000000000008516 177.0
HKD1_k127_2401277_5 Tellurite resistance protein TerB - - - 0.0000000000000000000000000000000004886 146.0
HKD1_k127_2401277_6 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.000000000000000000000000000003742 125.0
HKD1_k127_2401277_7 COG1145 Ferredoxin - - - 0.000000000000006414 85.0
HKD1_k127_2412533_0 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008242 350.0
HKD1_k127_2412533_1 Highly conserved protein containing a thioredoxin domain K06888 - - 0.000000000000000000000004092 111.0
HKD1_k127_2413701_0 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003735 436.0
HKD1_k127_2413701_1 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000786 415.0
HKD1_k127_2413701_2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K21310 - 2.1.1.334 0.000000000000000000000000000000000000000000000000000000000000000000000000000006353 269.0
HKD1_k127_2413701_3 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000007041 233.0
HKD1_k127_2413701_4 PFAM Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000002044 222.0
HKD1_k127_2413701_5 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000002056 155.0
HKD1_k127_2413701_6 Transcriptional - - - 0.000000000000000000000000000004853 132.0
HKD1_k127_2413701_7 Serine aminopeptidase, S33 - - - 0.000000000000001779 90.0
HKD1_k127_2413701_8 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.0000000003271 72.0
HKD1_k127_2423159_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 2.24e-229 736.0
HKD1_k127_2423159_1 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009227 371.0
HKD1_k127_2423159_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000001537 239.0
HKD1_k127_2423159_3 domain, Protein - - - 0.0000000000000000000000002534 113.0
HKD1_k127_2423159_4 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000001346 105.0
HKD1_k127_2423159_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02113,K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000128 76.0
HKD1_k127_2423159_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000000002475 65.0
HKD1_k127_2444773_0 response regulator receiver K07714,K10943 - - 0.000000000000348 82.0
HKD1_k127_2444773_1 protein involved in outer membrane biogenesis - - - 0.000002224 61.0
HKD1_k127_2446814_0 CoA-transferase family III K01796 - 5.1.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006882 503.0
HKD1_k127_2446814_1 Sugar (and other) transporter K03446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 486.0
HKD1_k127_2446814_2 PFAM secretion protein HlyD family protein K03543 - - 0.00000000000000000000000000000000000000000000000000000000229 223.0
HKD1_k127_2446814_3 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000002301 175.0
HKD1_k127_2446814_4 Predicted periplasmic protein (DUF2092) - - - 0.000000000000000000000000000000004502 135.0
HKD1_k127_2446814_5 - - - - 0.00000000000000000000000000003721 136.0
HKD1_k127_2446814_6 - - - - 0.00000002121 66.0
HKD1_k127_2454020_0 glutathione transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 331.0
HKD1_k127_2454020_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000518 147.0
HKD1_k127_2454020_2 MAPEG family - - - 0.0000000000000000000000000000000000001437 145.0
HKD1_k127_2454020_3 - - - - 0.000000000000000000000000000000000002905 155.0
HKD1_k127_2454020_4 Glutathione S-transferase, C-terminal domain - - - 0.000000000000000000000000000000000008359 146.0
HKD1_k127_2454020_5 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000001526 98.0
HKD1_k127_2454020_6 Protein of unknown function (DUF1232) - - - 0.00000000000000003442 92.0
HKD1_k127_2454020_7 - - - - 0.0000000000000003185 87.0
HKD1_k127_2454020_8 GDP-mannose mannosyl hydrolase activity K01515,K03574,K13669,K19710 GO:0000026,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.7.53,3.6.1.13,3.6.1.55 0.000000000000001193 88.0
HKD1_k127_2454020_9 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000001213 71.0
HKD1_k127_2478727_0 PFAM Type II secretion system protein E K02652 - - 1.323e-245 790.0
HKD1_k127_2478727_1 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 577.0
HKD1_k127_2478727_10 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000000000000000000000002939 158.0
HKD1_k127_2478727_11 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000004001 138.0
HKD1_k127_2478727_12 PFAM permease YjgP YjgQ family protein K11720 - - 0.00001066 57.0
HKD1_k127_2478727_13 - - - - 0.00005475 52.0
HKD1_k127_2478727_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 389.0
HKD1_k127_2478727_3 PFAM type II secretion system K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007659 334.0
HKD1_k127_2478727_4 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 323.0
HKD1_k127_2478727_5 Membrane-bound serine protease (ClpP class) K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004086 305.0
HKD1_k127_2478727_6 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000002426 256.0
HKD1_k127_2478727_7 HflC and HflK could regulate a protease K04087 - - 0.00000000000000000000000000000000000000000000000000000003877 216.0
HKD1_k127_2478727_8 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000000000000000000000000000000000000000000000000169 206.0
HKD1_k127_2478727_9 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000003278 181.0
HKD1_k127_2489352_0 Cytochrome P450 K05525,K20497 - 1.14.13.151,1.14.15.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 347.0
HKD1_k127_2489352_1 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000437 335.0
HKD1_k127_2489352_2 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 287.0
HKD1_k127_2489352_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000262 208.0
HKD1_k127_2489352_4 guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000001896 175.0
HKD1_k127_2489352_6 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000353 139.0
HKD1_k127_2489352_7 Ceramidase - - - 0.0000000000000001301 91.0
HKD1_k127_2489352_8 Dolichyl-phosphate-mannose-protein mannosyltransferase K14340 - - 0.0000002459 64.0
HKD1_k127_2496085_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1372.0
HKD1_k127_2496085_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 317.0
HKD1_k127_2496085_2 protein conserved in bacteria K09983 - - 0.0000000000000000000000000000000002359 134.0
HKD1_k127_2496085_3 Copper binding periplasmic protein CusF - - - 0.00000002077 68.0
HKD1_k127_2527628_0 - - - - 0.00000000000000000000000007716 125.0
HKD1_k127_2529244_0 Belongs to the alpha-IPM synthase homocitrate synthase family K09011 - 2.3.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008864 507.0
HKD1_k127_2529244_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000009581 196.0
HKD1_k127_2540245_0 MMPL family K07003 - - 0.000000000000000000000000000000000000000003127 178.0
HKD1_k127_2540245_1 PFAM Response regulator receiver domain - - - 0.000000000000000000000000000000000002128 153.0
HKD1_k127_2540245_2 translation initiation factor activity K06996 - - 0.0000000000000000000000008001 111.0
HKD1_k127_2540245_3 Histidine kinase - - - 0.00000000000000161 93.0
HKD1_k127_2540245_4 Outer membrane lipoprotein-sorting protein K07003 - - 0.00000000005086 74.0
HKD1_k127_2540245_5 Acyltransferase - - - 0.000000006705 57.0
HKD1_k127_2548901_0 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000008305 199.0
HKD1_k127_2548901_1 Lipid A biosynthesis K02517 - 2.3.1.241 0.00000000000000000001221 106.0
HKD1_k127_2548901_2 relative of glutathione S-transferase, MAPEG superfamily K07136 - - 0.00000000000000000004773 105.0
HKD1_k127_2548901_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00001349 47.0
HKD1_k127_2565804_0 PFAM SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001218 250.0
HKD1_k127_2565804_1 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000001528 207.0
HKD1_k127_2565804_2 ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000003352 219.0
HKD1_k127_2588967_0 Acyclic terpene utilisation family protein AtuA - - - 6.845e-217 700.0
HKD1_k127_2588967_1 Acetyl propionyl-CoA carboxylase, alpha subunit K01965,K01968 - 6.4.1.3,6.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 505.0
HKD1_k127_2588967_2 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005271 403.0
HKD1_k127_2588967_3 Fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001095 243.0
HKD1_k127_2588967_4 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.0000000000000000000000000000000000000000000001337 179.0
HKD1_k127_2588967_5 B domain of TMEM189, localisation domain K20656 - - 0.0000000000000000000000000000001253 136.0
HKD1_k127_2588967_6 transcriptional regulator - - - 0.00000000000000000000000002215 117.0
HKD1_k127_2588967_7 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000766 100.0
HKD1_k127_2588967_8 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000673 106.0
HKD1_k127_2588967_9 Forkhead associated domain - - - 0.0000000000001388 76.0
HKD1_k127_260305_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 374.0
HKD1_k127_260305_1 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003744 329.0
HKD1_k127_260305_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000003926 220.0
HKD1_k127_260305_3 PFAM Roadblock LC7 family protein - - - 0.0000000000000000000000000000000000000000000000000000000002399 206.0
HKD1_k127_260305_4 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000009004 164.0
HKD1_k127_260305_5 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006276,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010332,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042221,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0046677,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.00000000000001873 82.0
HKD1_k127_260305_6 YbaB/EbfC DNA-binding family K09747 - - 0.00000000000008476 85.0
HKD1_k127_260305_7 GDSL-like Lipase/Acylhydrolase - - - 0.000001098 57.0
HKD1_k127_260305_8 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000003836 57.0
HKD1_k127_2605713_0 PFAM FAD dependent oxidoreductase K00111 - 1.1.5.3 3.73e-199 637.0
HKD1_k127_2605713_1 COG2211 Na melibiose symporter and related transporters K03292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008217 287.0
HKD1_k127_2605713_2 PFAM ATP adenylyltransferase K00988 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000000000000000002194 255.0
HKD1_k127_2605713_3 lipolytic protein G-D-S-L family - - - 0.0000000000003728 84.0
HKD1_k127_2605713_4 PD-(D/E)XK nuclease superfamily - - - 0.00000003754 67.0
HKD1_k127_2608846_0 Carboxyl transferase domain - - - 3.382e-200 636.0
HKD1_k127_2608846_1 penicillin-binding protein - - - 0.00000000000000000000000000000000000000000000000000164 202.0
HKD1_k127_2608846_10 TOBE domain K02017 - 3.6.3.29 0.00000003783 64.0
HKD1_k127_2608846_11 CAAX protease self-immunity K01266,K07052 - 3.4.11.19 0.00000008381 63.0
HKD1_k127_2608846_2 Molybdate ABC transporter K02018 - - 0.000000000000000000000000000000000000000000000000008102 200.0
HKD1_k127_2608846_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000005372 189.0
HKD1_k127_2608846_4 Belongs to the UPF0301 (AlgH) family K07735 - - 0.000000000000000000000000000000000000000000005873 178.0
HKD1_k127_2608846_5 COG0694 Thioredoxin-like proteins and domains - - - 0.000000000000000000000000000000000000000001759 162.0
HKD1_k127_2608846_6 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000002289 143.0
HKD1_k127_2608846_7 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.000000000000000000000000005233 122.0
HKD1_k127_2608846_8 Haloacid dehalogenase-like hydrolase - - - 0.0000000000001165 83.0
HKD1_k127_2608846_9 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000001337 64.0
HKD1_k127_2621042_0 Cytochrome P450 - GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0005623,GO:0005886,GO:0006066,GO:0006629,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008395,GO:0009056,GO:0016020,GO:0016042,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016709,GO:0036199,GO:0044238,GO:0044281,GO:0044282,GO:0044464,GO:0046164,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616,GO:1902652 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 463.0
HKD1_k127_2621042_1 Protein of unknown function (DUF1214) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 400.0
HKD1_k127_2621042_2 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009019 391.0
HKD1_k127_2621042_3 carboxymuconolactone decarboxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 303.0
HKD1_k127_2621042_4 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000003323 209.0
HKD1_k127_2621042_5 transferase activity, transferring glycosyl groups K02844 - - 0.000000000000000000000000000000000007439 155.0
HKD1_k127_2639879_0 Mitochondrial fission ELM1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006713 414.0
HKD1_k127_2639879_1 ABC transporter K06148,K11085,K18217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 297.0
HKD1_k127_2639879_2 2OG-Fe(II) oxygenase superfamily - - - 0.0000000000000000000000000000000000000000000002098 176.0
HKD1_k127_2639879_3 Belongs to the RuBisCO large chain family K01601 - 4.1.1.39 0.000000000000000000000000000000000000009513 149.0
HKD1_k127_2653736_0 MCM2/3/5 family K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 438.0
HKD1_k127_2653736_1 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000981 366.0
HKD1_k127_2653736_2 cytochrome p450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 348.0
HKD1_k127_2653736_3 taurine catabolism dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005932 276.0
HKD1_k127_2653736_5 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000001782 217.0
HKD1_k127_2653736_6 ribosomal large subunit export from nucleus - - - 0.00000000000000000000000000000000000000000000000002279 184.0
HKD1_k127_2653736_7 Acyltransferase family - - - 0.0000000000000000003059 100.0
HKD1_k127_2653736_8 lipolytic protein G-D-S-L family K11751 - 3.1.3.5,3.6.1.45 0.0000000000000002519 93.0
HKD1_k127_2674979_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 545.0
HKD1_k127_2674979_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000006551 239.0
HKD1_k127_2674979_2 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000167 211.0
HKD1_k127_2674979_3 SIS domain K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000001704 183.0
HKD1_k127_2674979_4 Cro/C1-type HTH DNA-binding domain - - - 0.00000000000000000000000000000000000008836 162.0
HKD1_k127_2674979_5 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000000000005025 144.0
HKD1_k127_2674979_6 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.00000000000000001661 97.0
HKD1_k127_2674979_7 Dihydrodipicolinate synthase N-acetylneuraminate lyase K01714 - 4.3.3.7 0.00000003321 65.0
HKD1_k127_2675135_0 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000009343 224.0
HKD1_k127_2675135_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000466 183.0
HKD1_k127_2675135_2 Beta-lactamase - - - 0.0000000000000000000000000000000000000000001009 163.0
HKD1_k127_2675135_3 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000004546 159.0
HKD1_k127_2675135_4 PPIC-type PPIASE domain - - - 0.000000000000000000000000000000005325 141.0
HKD1_k127_2696386_0 Extracellular solute-binding protein, family 5 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008498 514.0
HKD1_k127_2696386_1 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005791 325.0
HKD1_k127_2696386_2 Catalyzes the synthesis of activated sulfate K00860 GO:0000096,GO:0000103,GO:0003674,GO:0003824,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010134,GO:0016740,GO:0016772,GO:0016779,GO:0019379,GO:0019419,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0070566,GO:0071704,GO:1901564 2.7.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 284.0
HKD1_k127_2696386_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000002175 224.0
HKD1_k127_2696386_4 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034,K15582 - - 0.00000000000000000000002274 114.0
HKD1_k127_2696386_5 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000002227 83.0
HKD1_k127_2709892_0 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 474.0
HKD1_k127_2709892_1 Histidine kinase K02668,K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001724 276.0
HKD1_k127_2709892_2 PFAM type II secretion system K02653 - - 0.00000000000000000000000000000000000000000000000000000000000008778 214.0
HKD1_k127_2715607_0 Acetyl-coenzyme A synthetase N-terminus K01907 - 6.2.1.16 4.962e-210 663.0
HKD1_k127_2733361_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006021 551.0
HKD1_k127_2733361_1 Glycosyl transferases group 1 K21001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 405.0
HKD1_k127_2733361_10 - - - - 0.0000000000000000000000000005325 127.0
HKD1_k127_2733361_11 Fkbm family - - - 0.0000000000000000000000000005352 123.0
HKD1_k127_2733361_12 PFAM Glycosyl transferase, group 1 K00754 - - 0.0000000000000000001077 93.0
HKD1_k127_2733361_13 O-Antigen ligase - - - 0.000000000000000003731 100.0
HKD1_k127_2733361_14 GDSL-like Lipase/Acylhydrolase - - - 0.000000006495 69.0
HKD1_k127_2733361_2 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001892 258.0
HKD1_k127_2733361_3 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001659 270.0
HKD1_k127_2733361_4 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000004974 245.0
HKD1_k127_2733361_5 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000004933 233.0
HKD1_k127_2733361_6 ATP-grasp - - - 0.00000000000000000000000000000000000000000000000000153 209.0
HKD1_k127_2733361_7 deacetylase - - - 0.00000000000000000000000000000000000000000000000568 184.0
HKD1_k127_2733361_8 methyltransferase - - - 0.0000000000000000000000000000000000000002111 162.0
HKD1_k127_2733361_9 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000008786 160.0
HKD1_k127_2735662_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.22e-233 753.0
HKD1_k127_2735662_1 TIGRFAM arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 517.0
HKD1_k127_2735662_2 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006811 477.0
HKD1_k127_2735662_3 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008831,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019305,GO:0019438,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901576 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000001359 222.0
HKD1_k127_2735662_4 cell redox homeostasis - - - 0.000000000000000000000000000000001055 136.0
HKD1_k127_2735662_5 Sporulation related domain - - - 0.000005638 57.0
HKD1_k127_274126_0 ABC transporter transmembrane region K18890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005518 475.0
HKD1_k127_274126_1 ABC-type multidrug transport system, ATPase and permease K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 393.0
HKD1_k127_274126_2 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 370.0
HKD1_k127_274126_3 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 381.0
HKD1_k127_274126_4 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000003068 261.0
HKD1_k127_274126_5 Glycosyl transferase family 2 K09931 - - 0.00000000000000000000000000000000000000000000000008641 186.0
HKD1_k127_274126_6 Mo-molybdopterin cofactor biosynthetic process - - - 0.0000000000000000000000000000000000000000004453 170.0
HKD1_k127_274126_7 protein conserved in bacteria K09778 - - 0.000000000000000000000001537 111.0
HKD1_k127_2778489_0 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 352.0
HKD1_k127_2778489_1 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000004292 218.0
HKD1_k127_2778489_2 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000838 156.0
HKD1_k127_2805091_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000004113 241.0
HKD1_k127_2805091_1 Mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000001433 209.0
HKD1_k127_2805091_2 PFAM Bacterial regulatory proteins, crp family K10914 - - 0.0000000000000000000000000000000000001366 151.0
HKD1_k127_2805091_3 protein containing LysM domain - - - 0.000000000000000000000000000000000004087 155.0
HKD1_k127_2816470_0 Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 379.0
HKD1_k127_2816470_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000003663 181.0
HKD1_k127_2816470_2 PFAM pyridoxamine 5'-phosphate - - - 0.00000000000000000000000000000000002473 144.0
HKD1_k127_2816470_3 - - - - 0.000000000003956 80.0
HKD1_k127_2840750_0 Lysylphosphatidylglycerol synthase TM region K07027,K14205 - 2.3.2.3 3.251e-258 829.0
HKD1_k127_2840750_1 AMP-binding enzyme C-terminal domain - - - 5.418e-194 619.0
HKD1_k127_2840750_10 Serine aminopeptidase, S33 - - - 0.00000000000000000001867 104.0
HKD1_k127_2840750_11 light absorption - - - 0.00004152 57.0
HKD1_k127_2840750_2 Pfam Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 501.0
HKD1_k127_2840750_3 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 423.0
HKD1_k127_2840750_4 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 362.0
HKD1_k127_2840750_5 Phytanoyl-CoA dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009332 339.0
HKD1_k127_2840750_6 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005856 343.0
HKD1_k127_2840750_7 PFAM virulence factor family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 316.0
HKD1_k127_2840750_8 Phosphotriesterase family K07048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000177 289.0
HKD1_k127_2840750_9 isochorismatase, hydrolase - - - 0.00000000000000000000000000000000000002321 148.0
HKD1_k127_2919848_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 6.231e-213 683.0
HKD1_k127_2919848_1 Phosphate sensor histidine kinase, HAMP and PAS domain-containing K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000003211 254.0
HKD1_k127_2919848_2 Two component transcriptional regulator, winged helix family K07657 - - 0.00000000000000000000000000000000000000000002413 171.0
HKD1_k127_2919848_3 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000001155 155.0
HKD1_k127_2919848_4 Carboxylate--amine ligase - - - 0.0000000000000009141 79.0
HKD1_k127_2954580_0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 563.0
HKD1_k127_2954580_1 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 385.0
HKD1_k127_2954580_2 transcriptional regulator - - - 0.00000000000000000003327 99.0
HKD1_k127_2954580_3 PFAM Phage derived protein Gp49-like (DUF891) - - - 0.0000000001487 70.0
HKD1_k127_2954580_4 PFAM phosphate acetyl butaryl transferase K00625 - 2.3.1.8 0.000000001158 59.0
HKD1_k127_2954580_5 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.00000004705 55.0
HKD1_k127_296563_0 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008621 334.0
HKD1_k127_296563_1 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 294.0
HKD1_k127_3001437_0 NAD binding K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 476.0
HKD1_k127_3001437_1 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000004056 256.0
HKD1_k127_3001437_2 Biotin/lipoate A/B protein ligase family K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000006086 196.0
HKD1_k127_3001437_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000001253 177.0
HKD1_k127_3001437_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K02573 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000001198 175.0
HKD1_k127_3001437_5 Protein conserved in bacteria K09986 - - 0.0000000000005988 76.0
HKD1_k127_3037730_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 511.0
HKD1_k127_3037730_1 'glutamate synthase K00123,K00317,K00528,K09835 - 1.17.1.9,1.18.1.2,1.19.1.1,1.5.8.1,1.5.8.2,5.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004499 319.0
HKD1_k127_3037730_2 Acyl-CoA synthetase (NDP forming) - - - 0.0000000000000000000000000000000000000000000002294 174.0
HKD1_k127_3037730_3 - - - - 0.000000000000000000000009406 106.0
HKD1_k127_3037730_4 COG2010 Cytochrome c, mono- and diheme variants - - - 0.000000000000000000000558 105.0
HKD1_k127_3037730_5 - - - - 0.0000000000000000003934 101.0
HKD1_k127_3043834_0 O-methyltransferase K00588 - 2.1.1.104 0.0000000000000000000000000000000000000001185 152.0
HKD1_k127_3043834_1 O-Methyltransferase K00588 - 2.1.1.104 0.00000000000000000000000000000000104 132.0
HKD1_k127_3043834_2 NADPH-dependent FMN reductase - - - 0.000000000000000000008197 98.0
HKD1_k127_3043834_3 peptidyl-tyrosine sulfation - - - 0.0000000000001438 76.0
HKD1_k127_3048758_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000961 455.0
HKD1_k127_3048758_1 PFAM phosphoesterase, RecJ domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006868 294.0
HKD1_k127_3048758_2 PFAM aldo keto reductase K07079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003874 276.0
HKD1_k127_3048758_3 Bacterial periplasmic substrate-binding proteins K01713 - 4.2.1.51,4.2.1.91 0.000000000000000000000000000000000000000000000000000000000000000000000005161 256.0
HKD1_k127_3048758_4 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000009702 198.0
HKD1_k127_3048758_5 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.0000000000000000000000000000000000000004443 159.0
HKD1_k127_3048758_6 dehydratase - - - 0.00000000000000000000001333 107.0
HKD1_k127_3048758_7 Cold shock protein K03704 - - 0.000000002898 67.0
HKD1_k127_3057931_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 427.0
HKD1_k127_3057931_1 Integrase core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001622 271.0
HKD1_k127_3057973_0 acyl-CoA dehydrogenase activity K00252 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.3.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000671 477.0
HKD1_k127_3057973_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648,K18003 - 2.3.1.180,2.3.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005651 355.0
HKD1_k127_3057973_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 336.0
HKD1_k127_3057973_3 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.00000000000000000000000000000000000000000000000000000000000000000004007 241.0
HKD1_k127_3072086_0 COG0488 ATPase components of ABC transporters with duplicated ATPase domains - - - 1.029e-257 806.0
HKD1_k127_3072086_1 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000437 490.0
HKD1_k127_3072086_2 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 324.0
HKD1_k127_3072086_3 TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000003664 223.0
HKD1_k127_3072086_4 hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000001464 201.0
HKD1_k127_3072086_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000005274 155.0
HKD1_k127_3072086_6 glutathione transferase activity - - - 0.0000000000000000000000000000001372 126.0
HKD1_k127_3072086_7 lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.000000000000000000000000000008485 139.0
HKD1_k127_3072086_8 guanyl-nucleotide exchange factor activity - - - 0.0000000007959 72.0
HKD1_k127_3078191_0 Dehydrogenase K00114,K17760,K22473 - 1.1.2.8,1.1.5.5,1.1.9.1 1.128e-219 710.0
HKD1_k127_3078191_1 Pfam:Pyridox_oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001269 241.0
HKD1_k127_3078191_2 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000002406 190.0
HKD1_k127_3078191_3 homolog of gamma-carboxymuconolactone decarboxylase subunit K01607 - 4.1.1.44 0.0000000000000000000000000000000006967 134.0
HKD1_k127_3078191_4 Lipid A 3-O-deacylase (PagL) - - - 0.000000000000000000000000002002 122.0
HKD1_k127_3078191_5 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000006195 100.0
HKD1_k127_3078191_6 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00005153 57.0
HKD1_k127_3078191_7 Kazal type serine protease inhibitors - - - 0.00008951 56.0
HKD1_k127_3078191_8 long-chain fatty acid transport protein - - - 0.0009906 45.0
HKD1_k127_3088265_0 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008289,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031406,GO:0031975,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042277,GO:0042546,GO:0042597,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071723,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 472.0
HKD1_k127_3088265_1 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 413.0
HKD1_k127_3088265_10 Polynucleotide adenylyltransferase K00974 - 2.7.7.72 0.00000000000000000000000000000000005734 155.0
HKD1_k127_3088265_2 geranylgeranyl reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 382.0
HKD1_k127_3088265_3 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 317.0
HKD1_k127_3088265_4 TIM-barrel fold metal-dependent hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007715 254.0
HKD1_k127_3088265_5 Spermidine synthase K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000003223 237.0
HKD1_k127_3088265_6 Sigma-70 factor, region 1.2 K03086 - - 0.00000000000000000000000000000000000000000000000000003576 208.0
HKD1_k127_3088265_7 SnoaL-like domain - - - 0.00000000000000000000000000000000000000005088 156.0
HKD1_k127_3088265_8 SnoaL-like domain K01822 - 5.3.3.1 0.000000000000000000000000000000000000001707 151.0
HKD1_k127_3088265_9 cog0421, spermidine synthase - - - 0.000000000000000000000000000000000005464 141.0
HKD1_k127_3092651_0 Aminotransferase class I and II K00375 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 524.0
HKD1_k127_3092651_1 Flavin-nucleotide-binding protein K07005 - - 0.00000000000000000000000000000000000000000000000000000001611 226.0
HKD1_k127_3092651_2 acetyltransferase - - - 0.0000000000000000000000000000001998 134.0
HKD1_k127_3092651_3 other phosphorylase family 1 K01243 - 3.2.2.9 0.000000000000000000000001267 112.0
HKD1_k127_3092651_4 Polymer-forming cytoskeletal - - - 0.00000000000001783 79.0
HKD1_k127_3103920_0 DEAD DEAH box K03724 - - 8.285e-250 797.0
HKD1_k127_3103920_1 PFAM CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004616 507.0
HKD1_k127_3153525_0 Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 448.0
HKD1_k127_3153525_1 Glutamate-cysteine ligase family 2(GCS2) K01919 - 6.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 425.0
HKD1_k127_3153525_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 349.0
HKD1_k127_3153525_3 PFAM Peptidase M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002943 293.0
HKD1_k127_3153525_4 Response regulator receiver domain - - - 0.0000000000000000000000000000008368 137.0
HKD1_k127_3153525_5 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000000002802 127.0
HKD1_k127_3153525_6 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000000000000003759 115.0
HKD1_k127_3153525_8 FR47-like protein - - - 0.000001245 60.0
HKD1_k127_3161414_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 6.195e-215 676.0
HKD1_k127_3161414_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 GO:0000271,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901576 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 430.0
HKD1_k127_3161414_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000005247 110.0
HKD1_k127_3161414_3 PFAM CBS domain containing protein K04767 - - 0.000000000000008557 84.0
HKD1_k127_3161414_4 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.0000000000014 78.0
HKD1_k127_3161414_5 'Cold-shock' DNA-binding domain - - - 0.000000004858 67.0
HKD1_k127_3161414_6 DnaK suppressor protein - - - 0.00000002035 65.0
HKD1_k127_3161414_7 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000005049 61.0
HKD1_k127_3161414_8 DksA TraR C4-type K06204 - - 0.000001546 59.0
HKD1_k127_3170052_0 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 1.747e-305 966.0
HKD1_k127_3170052_1 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009354 435.0
HKD1_k127_3170052_2 Belongs to the phosphatidylserine decarboxylase family K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000001554 223.0
HKD1_k127_3170052_3 ATP-NAD kinase - - - 0.000000000000000000000000000000000000000000000000000002851 214.0
HKD1_k127_3170052_4 Lipase maturation factor - - - 0.0000000000000000000000000000000000000000002273 165.0
HKD1_k127_3177809_0 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 389.0
HKD1_k127_3177809_1 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000002807 264.0
HKD1_k127_3177809_2 Alkyl hydroperoxide reductase K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000001274 216.0
HKD1_k127_3177809_3 May be involved in the transport of PQQ or its precursor to the periplasm K06136 - - 0.0000000000000000000000000000000000000000000000000000003398 204.0
HKD1_k127_3177809_4 response to heat K07090 - - 0.0000000000000000000000000000000000005399 159.0
HKD1_k127_3177809_5 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07714 - - 0.00000000000000000000000000000000002987 150.0
HKD1_k127_3180631_0 L,D-transpeptidase catalytic domain K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 398.0
HKD1_k127_3180631_1 Smr domain - - - 0.0000000000000000000000000003686 119.0
HKD1_k127_3180978_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 3.751e-307 981.0
HKD1_k127_3180978_1 PFAM AMP-dependent synthetase and ligase K01897,K22319 - 6.1.3.1,6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 546.0
HKD1_k127_3180978_10 PFAM Sulfotransferase domain - - - 0.00000000000000000000000000000000000000000000000000838 187.0
HKD1_k127_3180978_11 KR domain K07124 - - 0.000000000000000000000000000000000000000000000001561 189.0
HKD1_k127_3180978_12 - - - - 0.000000000000000000000000000000000000000000000001664 187.0
HKD1_k127_3180978_13 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000002909 199.0
HKD1_k127_3180978_14 Ribosomal RNA adenine dimethylase K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000006489 171.0
HKD1_k127_3180978_15 EVE domain - - - 0.000000000000000000000000000000000000000005366 158.0
HKD1_k127_3180978_16 PEP-CTERM motif - - - 0.000000000000000000000000000000000000000007918 166.0
HKD1_k127_3180978_17 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000171 170.0
HKD1_k127_3180978_18 PFAM OsmC family protein - - - 0.0000000000000000000000000000000000000001849 172.0
HKD1_k127_3180978_19 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000003479 168.0
HKD1_k127_3180978_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 481.0
HKD1_k127_3180978_20 Nitroreductase family - - - 0.000000000000000000000000000000000008433 145.0
HKD1_k127_3180978_21 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000007083 101.0
HKD1_k127_3180978_22 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000003142 111.0
HKD1_k127_3180978_23 Cupin 2, conserved barrel domain protein - - - 0.00000007374 62.0
HKD1_k127_3180978_24 C-terminal domain of CHU protein family - - - 0.0005731 50.0
HKD1_k127_3180978_3 alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004146 443.0
HKD1_k127_3180978_4 SMART Tetratricopeptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 425.0
HKD1_k127_3180978_5 acyl-CoA dehydrogenase K18244 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003179 279.0
HKD1_k127_3180978_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000008893 242.0
HKD1_k127_3180978_7 chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000004101 234.0
HKD1_k127_3180978_8 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000001712 229.0
HKD1_k127_3180978_9 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000285 205.0
HKD1_k127_3181370_0 cytochrome p450 K16046 - 1.14.13.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004318 408.0
HKD1_k127_3181370_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 386.0
HKD1_k127_3181370_2 acyl-CoA dehydrogenase K00257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 359.0
HKD1_k127_3181370_3 Zinc-uptake complex component A periplasmic K09815 - - 0.000000000000000000000000000000000000000000000000000000000143 217.0
HKD1_k127_3181370_4 Tfp pilus assembly protein FimV - - - 0.0000000000000000000000000000000001753 150.0
HKD1_k127_3181370_5 PFAM Major Facilitator Superfamily - - - 0.000002686 59.0
HKD1_k127_3230734_0 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000001435 175.0
HKD1_k127_3230734_1 Histidine kinase - - - 0.000000000000000000001532 98.0
HKD1_k127_3240113_0 Periplasmic copper-binding protein (NosD) K07218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005408 264.0
HKD1_k127_3240113_1 lipoprotein involved in nitrous oxide reduction - - - 0.00000000000000000000000000000000000000000000000000001089 198.0
HKD1_k127_3240113_2 abc transporter atp-binding protein K01990 - - 0.0000000000000000000000000000000000000000005201 179.0
HKD1_k127_3240113_3 NUDIX domain - - - 0.000000000000000000000000002128 119.0
HKD1_k127_3240113_4 ABC-2 family transporter protein K19341 - - 0.000000000000000002885 98.0
HKD1_k127_3240113_5 lipoprotein involved in nitrous oxide reduction K19342 - - 0.00000002231 62.0
HKD1_k127_3240113_6 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 0.0001978 53.0
HKD1_k127_3244325_0 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 3.794e-209 666.0
HKD1_k127_3244325_1 Belongs to the sigma-70 factor family K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 557.0
HKD1_k127_3244325_10 ABC transporter ATPase permease K06147 - - 0.000000000000000001406 85.0
HKD1_k127_3244325_11 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000004665 87.0
HKD1_k127_3244325_12 enzyme related to lactoylglutathione lyase K06996 - - 0.0000000003836 65.0
HKD1_k127_3244325_2 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 490.0
HKD1_k127_3244325_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 334.0
HKD1_k127_3244325_4 dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes K13356 - 1.2.1.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000142 298.0
HKD1_k127_3244325_5 WYL domain - - - 0.000000000000000000000000000000000000000000000000000000000000001459 227.0
HKD1_k127_3244325_6 Belongs to the GST superfamily K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000003687 209.0
HKD1_k127_3244325_7 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000000003581 154.0
HKD1_k127_3244325_8 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000003557 156.0
HKD1_k127_3244325_9 YCII-related domain - - - 0.00000000000000000000000000000000003648 142.0
HKD1_k127_3264581_0 Molydopterin dinucleotide binding domain K00123,K00372 - 1.17.1.9 1.686e-221 734.0
HKD1_k127_3264581_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005591 343.0
HKD1_k127_3264581_2 - - - - 0.00000000000000000000000587 103.0
HKD1_k127_3264581_3 Required for optimal acid stress protection. Exhibits a chaperone-like activity only at low pH by suppressing non- specifically the aggregation of denaturated periplasmic proteins K19777 GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0042802,GO:0050896,GO:0051087,GO:0051716,GO:0071214,GO:0071467,GO:0071468,GO:0104004 - 0.00000005301 63.0
HKD1_k127_3267456_0 cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007758 604.0
HKD1_k127_3267456_1 cytochrome p450 K17474 - 1.14.15.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 452.0
HKD1_k127_3267456_2 Dehydrogenase reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000815 398.0
HKD1_k127_3267456_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005108 331.0
HKD1_k127_3267456_4 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000003073 106.0
HKD1_k127_3267456_5 COG0208 Ribonucleotide reductase, beta subunit - - - 0.000000000000000000001257 108.0
HKD1_k127_3267456_6 Bacterial regulatory proteins, tetR family - - - 0.000000000009533 74.0
HKD1_k127_3293619_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647 - 2.3.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 517.0
HKD1_k127_3293619_1 acyl-CoA transferase carnitine dehydratase K18702 - 2.8.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004726 394.0
HKD1_k127_3293619_10 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000006541 190.0
HKD1_k127_3293619_11 Methylmuconolactone methyl-isomerase - - - 0.00000000000000000000000000000000000000007882 166.0
HKD1_k127_3293619_12 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity K02372 - 4.2.1.59 0.000000000000000000000000000000000000006247 159.0
HKD1_k127_3293619_13 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000004561 87.0
HKD1_k127_3293619_14 oligosaccharyl transferase activity - - - 0.00000000000000003472 96.0
HKD1_k127_3293619_2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 377.0
HKD1_k127_3293619_3 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005973 304.0
HKD1_k127_3293619_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005371 297.0
HKD1_k127_3293619_5 Enoyl-CoA hydratase carnithine racemase K01692,K11264 - 4.1.1.41,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000001747 258.0
HKD1_k127_3293619_6 Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length K01716 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0008693,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016863,GO:0019171,GO:0019752,GO:0032787,GO:0034017,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0047451,GO:0071704,GO:0072330,GO:1901576 4.2.1.59,5.3.3.14 0.0000000000000000000000000000000000000000000000000000000000000000002725 249.0
HKD1_k127_3293619_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000001891 197.0
HKD1_k127_3293619_8 Acetyl propionyl-CoA carboxylase, alpha subunit - - - 0.0000000000000000000000000000000000000000000000000005398 202.0
HKD1_k127_3293619_9 Acyl-transferase - - - 0.0000000000000000000000000000000000000000000000000009719 196.0
HKD1_k127_3332003_0 Bacterial virulence protein (VirJ) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005429 279.0
HKD1_k127_3332003_1 FHA domain - - - 0.00000005642 63.0
HKD1_k127_3354708_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 3.938e-282 881.0
HKD1_k127_3354708_1 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 466.0
HKD1_k127_3354708_10 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000001098 105.0
HKD1_k127_3354708_11 PFAM Smr - - - 0.000001239 59.0
HKD1_k127_3354708_2 A G-specific adenine glycosylase K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008594 332.0
HKD1_k127_3354708_3 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002104 275.0
HKD1_k127_3354708_4 HRDC domain K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000006331 202.0
HKD1_k127_3354708_5 Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000001644 199.0
HKD1_k127_3354708_6 Amino-transferase class IV K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000001211 196.0
HKD1_k127_3354708_7 Transcriptional regulator K02624,K13641 - - 0.0000000000000000000000000000000000000000001177 173.0
HKD1_k127_3354708_8 FIST N domain - - - 0.000000000000000000000000000000002833 143.0
HKD1_k127_3354708_9 alpha-ribazole phosphatase activity K02226,K15634,K15640 - 3.1.3.73,5.4.2.12 0.000000000000000000000000000000007255 136.0
HKD1_k127_3356558_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052,K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000053 374.0
HKD1_k127_3356558_1 Amidase K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000001535 173.0
HKD1_k127_3356558_2 3-demethylubiquinone-9 3-O-methyltransferase activity K15257 - - 0.00000000000000000000000000000000000554 146.0
HKD1_k127_3356558_3 Domain of unknown function (DUF4136) - - - 0.00000000000000000000000000001411 127.0
HKD1_k127_3356558_4 - - - - 0.000000000000000000000000803 108.0
HKD1_k127_3357286_0 FecR protein - - - 1.851e-277 897.0
HKD1_k127_3357286_1 Luciferase-like monooxygenase - - - 2.764e-203 640.0
HKD1_k127_3357286_2 Glutaminase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008709 551.0
HKD1_k127_3357286_3 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 554.0
HKD1_k127_3357286_4 Serine aminopeptidase, S33 K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000001849 265.0
HKD1_k127_3357286_5 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000000000002493 141.0
HKD1_k127_3357286_6 Nuclear transport factor 2 (NTF2) domain K01822 - 5.3.3.1 0.000000000000000000001775 104.0
HKD1_k127_3357286_7 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000001046 78.0
HKD1_k127_3357286_8 - - - - 0.00000004872 62.0
HKD1_k127_336185_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009223 450.0
HKD1_k127_336185_1 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 378.0
HKD1_k127_3363889_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 2.6e-306 960.0
HKD1_k127_3363889_1 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 289.0
HKD1_k127_3363889_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000006271 189.0
HKD1_k127_3363889_3 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000004205 166.0
HKD1_k127_3363889_4 - - - - 0.00000000000000000000009448 112.0
HKD1_k127_3376857_0 Aminotransferase class I and II K14267 - 2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 435.0
HKD1_k127_3376857_1 ADP-glyceromanno-heptose 6-epimerase activity K00311 - 1.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006801 296.0
HKD1_k127_3376857_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000619 268.0
HKD1_k127_3376857_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000004149 255.0
HKD1_k127_3376857_4 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.0000000000000000000000000000000000000000000000000000002442 200.0
HKD1_k127_3376857_5 Peptidase C26 K07010 - - 0.000000000000000000000000000002982 130.0
HKD1_k127_3376857_6 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.0000000000000002551 91.0
HKD1_k127_3376857_7 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00360,K00362,K02192 - 1.7.1.15 0.0001658 50.0
HKD1_k127_3391679_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 507.0
HKD1_k127_3391679_1 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 328.0
HKD1_k127_3391679_2 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000004429 114.0
HKD1_k127_3391679_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000001163 111.0
HKD1_k127_3419681_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 5.696e-274 850.0
HKD1_k127_3419681_1 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01835 - 5.4.2.2 5.187e-255 820.0
HKD1_k127_3419681_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 514.0
HKD1_k127_3419681_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K03286 - - 0.00000000000000000000000000002325 135.0
HKD1_k127_3436691_0 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007238 284.0
HKD1_k127_3436691_1 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000005974 259.0
HKD1_k127_3436691_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000001826 205.0
HKD1_k127_3436691_3 methyltransferase - - - 0.0000000000000000000000000000000000000000000009302 181.0
HKD1_k127_3436691_4 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000001862 188.0
HKD1_k127_3436691_5 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000005699 158.0
HKD1_k127_3456296_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 613.0
HKD1_k127_3456296_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 500.0
HKD1_k127_3456296_10 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000001052 228.0
HKD1_k127_3456296_11 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000002186 181.0
HKD1_k127_3456296_12 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000169 190.0
HKD1_k127_3456296_13 Semialdehyde dehydrogenase, NAD binding domain K00133 - 1.2.1.11 0.0000000000000000000000000000000006854 153.0
HKD1_k127_3456296_14 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000007481 113.0
HKD1_k127_3456296_15 Glycoprotease family K14742 - - 0.00000000000000000000004382 116.0
HKD1_k127_3456296_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 408.0
HKD1_k127_3456296_3 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 400.0
HKD1_k127_3456296_4 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006302 313.0
HKD1_k127_3456296_5 Peptidase family M50 K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002213 303.0
HKD1_k127_3456296_6 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001177 273.0
HKD1_k127_3456296_7 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000009857 267.0
HKD1_k127_3456296_8 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000008383 256.0
HKD1_k127_3456296_9 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000001004 229.0
HKD1_k127_347010_0 GMC oxidoreductase - - - 2.593e-251 785.0
HKD1_k127_347010_1 Protein of unknown function (DUF3604) - - - 8.001e-206 659.0
HKD1_k127_347010_2 Domain of unknown function (DUF4410) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005592 255.0
HKD1_k127_347010_3 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine - - - 0.00000000000000000000000000000000000000000000000000000000000000003131 233.0
HKD1_k127_347010_4 Protein of unknown function (DUF429) - - - 0.00000000000000000000000000000000000000000000000325 187.0
HKD1_k127_347010_5 - - - - 0.00000000000001083 81.0
HKD1_k127_347010_6 Pfam Amidohydrolase - - - 0.000000006356 57.0
HKD1_k127_3470779_0 STAS domain - - - 1.163e-203 659.0
HKD1_k127_3470779_1 citrate synthase K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005181 570.0
HKD1_k127_3470779_2 COG0695 glutaredoxin and related proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009755 316.0
HKD1_k127_3470779_3 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002157 302.0
HKD1_k127_3470779_4 Enoyl-(Acyl carrier protein) reductase K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000002143 238.0
HKD1_k127_3470779_5 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000004026 250.0
HKD1_k127_3470779_6 Translation initiation factor SUI1 K03113 - - 0.00000000000000000000000000000000000004039 155.0
HKD1_k127_3470779_7 CoA-binding protein K06929 - - 0.000000000000000000000000000000001003 135.0
HKD1_k127_3470779_9 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K02619 - 4.1.3.38 0.0006136 53.0
HKD1_k127_3477481_0 DEAD/H associated K03724 - - 0.0 1101.0
HKD1_k127_3477808_0 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 432.0
HKD1_k127_3477808_1 Glucose sorbosone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004051 402.0
HKD1_k127_3477808_2 belongs to the sigma-70 factor family K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 292.0
HKD1_k127_3477808_3 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002982 289.0
HKD1_k127_3477808_4 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000145 282.0
HKD1_k127_3477808_5 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000005968 170.0
HKD1_k127_3477808_6 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000009155 157.0
HKD1_k127_3477808_7 YCII-related domain - - - 0.0000000000000000000000198 108.0
HKD1_k127_3500167_0 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 387.0
HKD1_k127_3500167_1 ATPase associated with various cellular K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007649 329.0
HKD1_k127_3500167_2 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000002053 203.0
HKD1_k127_3500167_3 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000008564 191.0
HKD1_k127_3531066_0 TIGRFAM cytochrome c oxidase accessory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006237 299.0
HKD1_k127_3531066_1 PFAM cytochrome c, class I K00406 - - 0.000000000000000000000001395 113.0
HKD1_k127_3531066_2 COG2217 Cation transport ATPase K01533 - 3.6.3.4 0.000000000000003585 81.0
HKD1_k127_3541591_0 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 302.0
HKD1_k127_3541591_1 Rieske 2Fe-2S - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008073 293.0
HKD1_k127_3541591_2 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000001043 254.0
HKD1_k127_3541591_3 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000002229 179.0
HKD1_k127_3541591_4 transcriptional regulator K22107 - - 0.0000000000000000000001457 113.0
HKD1_k127_3557135_0 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.000000000000000000000001782 106.0
HKD1_k127_3557135_1 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000000000000001213 103.0
HKD1_k127_3557135_2 DinB superfamily - - - 0.0003862 51.0
HKD1_k127_3560480_0 NADPH quinone K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 353.0
HKD1_k127_3560480_1 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008979 302.0
HKD1_k127_3560480_10 Glyoxalase-like domain - - - 0.00000000000000000000000000001412 124.0
HKD1_k127_3560480_11 Ion transport 2 domain protein - - - 0.0000000000000000000000236 109.0
HKD1_k127_3560480_12 ABC-2 type transporter K01992 - - 0.000001012 55.0
HKD1_k127_3560480_2 Belongs to the MIP aquaporin (TC 1.A.8) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000621 288.0
HKD1_k127_3560480_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000007656 263.0
HKD1_k127_3560480_4 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000002766 269.0
HKD1_k127_3560480_5 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741,K03892 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000000000002468 228.0
HKD1_k127_3560480_6 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000003811 234.0
HKD1_k127_3560480_7 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000008736 168.0
HKD1_k127_3560480_8 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.0000000000000000000000000000000000000002965 149.0
HKD1_k127_3560480_9 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000000000000000002459 148.0
HKD1_k127_3582319_0 Aldehyde dehydrogenase family - - - 6.69e-223 700.0
HKD1_k127_3582319_1 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 546.0
HKD1_k127_3582319_10 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000006539 210.0
HKD1_k127_3582319_11 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000518 158.0
HKD1_k127_3582319_12 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000001814 105.0
HKD1_k127_3582319_13 Prokaryotic Cytochrome C oxidase subunit IV - - - 0.00000000000000000001348 94.0
HKD1_k127_3582319_2 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 502.0
HKD1_k127_3582319_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 457.0
HKD1_k127_3582319_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009771 379.0
HKD1_k127_3582319_5 Carboxylesterase family K01066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006488 317.0
HKD1_k127_3582319_6 Oxidoreductase FAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007142 314.0
HKD1_k127_3582319_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001175 289.0
HKD1_k127_3582319_8 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001716 248.0
HKD1_k127_3582319_9 cytochrome c oxidase, subunit III K02164 - - 0.000000000000000000000000000000000000000000000000000000000000000000003806 251.0
HKD1_k127_3584890_0 AMP-binding enzyme C-terminal domain K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 609.0
HKD1_k127_3584890_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00850,K00895,K21071 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 430.0
HKD1_k127_3584890_10 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000004719 105.0
HKD1_k127_3584890_11 COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III K00784 - 3.1.26.11 0.00000000000000009814 94.0
HKD1_k127_3584890_12 Rhomboid family - - - 0.00000000003279 76.0
HKD1_k127_3584890_13 Peptidase family M28 - - - 0.0003952 53.0
HKD1_k127_3584890_2 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791,K13019 - 5.1.3.14,5.1.3.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 441.0
HKD1_k127_3584890_3 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004388 369.0
HKD1_k127_3584890_4 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004906 342.0
HKD1_k127_3584890_5 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 309.0
HKD1_k127_3584890_6 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000001272 231.0
HKD1_k127_3584890_7 NUBPL iron-transfer P-loop NTPase - - - 0.00000000000000000000000000000000000000000000001502 186.0
HKD1_k127_3584890_8 Pfam Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000004132 172.0
HKD1_k127_3584890_9 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000002009 126.0
HKD1_k127_3596265_0 ArgK protein K11942 - 5.4.99.13 0.0 1296.0
HKD1_k127_3596265_1 Carboxyl transferase domain - - - 1.495e-195 617.0
HKD1_k127_3596265_2 TIGRFAM methylmalonyl-CoA mutase N-terminal domain K01847,K01848 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 374.0
HKD1_k127_3596265_4 Transcription regulator MerR DNA binding K21902 - - 0.000000000000000000000000114 117.0
HKD1_k127_3605758_0 Belongs to the folylpolyglutamate synthase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009688 263.0
HKD1_k127_3605758_1 Melibiase K07407 - 3.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000171 279.0
HKD1_k127_3605758_2 Homocysteine S-methyltransferase K00547,K21169 - 2.1.1.10 0.00000000000000000000000000000000000000000000000000005125 216.0
HKD1_k127_3605758_3 Transport and Golgi organisation 2 - - - 0.0000000000000000000000000000000000000000001032 170.0
HKD1_k127_3605758_4 Putative Phosphatase - - - 0.0000000000000000000002287 115.0
HKD1_k127_3605758_5 (mono)amine oxidase K00274 - 1.4.3.4 0.0000005414 61.0
HKD1_k127_3616297_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.298e-251 782.0
HKD1_k127_3616297_1 PDZ domain (Also known as DHR or GLGF) K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 495.0
HKD1_k127_3616297_2 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 309.0
HKD1_k127_3616297_3 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000251 214.0
HKD1_k127_3616297_4 nitroreductase - - - 0.000000000000000000000000000000000003243 138.0
HKD1_k127_3616297_5 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000001728 134.0
HKD1_k127_3616297_6 Belongs to the BolA IbaG family K05527 - - 0.0000000000000000007227 89.0
HKD1_k127_3616297_7 Domain of unknown function (DUF4129) - - - 0.0001579 50.0
HKD1_k127_363483_0 Multicopper oxidase K00368 - 1.7.2.1 3.054e-195 621.0
HKD1_k127_363483_1 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000000000000000006072 218.0
HKD1_k127_363483_2 Helix-turn-helix - - - 0.00000000000000000000000000000005455 130.0
HKD1_k127_363483_3 signal sequence binding K07152 - - 0.000000000000000000000000000216 130.0
HKD1_k127_363483_4 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000004388 106.0
HKD1_k127_363483_5 - - - - 0.0000000000000003318 89.0
HKD1_k127_363483_6 aminopeptidase activity - - - 0.0000000003683 72.0
HKD1_k127_3650392_0 Flavoprotein involved in K transport K03379 - 1.14.13.22 0.000000000000009809 74.0
HKD1_k127_3650392_1 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000001177 61.0
HKD1_k127_3650392_2 - - - - 0.0002274 44.0
HKD1_k127_3650392_3 Recombinase - - - 0.0002425 44.0
HKD1_k127_3650392_4 Helix-turn-helix domain - - - 0.0004438 47.0
HKD1_k127_3734507_0 COG1884 Methylmalonyl-CoA mutase, N-terminal domain subunit K14447 - 5.4.99.63 2.6e-287 896.0
HKD1_k127_3734507_1 ArgK protein K07588 - - 0.000000000000000000000000000000000000000000000000000000000000001624 230.0
HKD1_k127_3734507_2 aminotransferase class I and II - - - 0.0000000000000000000000000225 116.0
HKD1_k127_3745152_0 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 501.0
HKD1_k127_3745152_1 PFAM Binding-protein-dependent transport system inner membrane component K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009945 492.0
HKD1_k127_3745152_2 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003741 449.0
HKD1_k127_3745152_3 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009237 428.0
HKD1_k127_3745152_4 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 424.0
HKD1_k127_3745152_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007307 327.0
HKD1_k127_3745152_6 Phosphate-selective porin O and P K07221 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 314.0
HKD1_k127_3745152_7 - - - - 0.0000000000000000000000000000000000000001656 153.0
HKD1_k127_3745152_8 Methyltransferase domain - - - 0.00000000000000000000000000000000000001407 153.0
HKD1_k127_3745152_9 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000006802 148.0
HKD1_k127_376039_0 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003611 381.0
HKD1_k127_376039_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 291.0
HKD1_k127_376039_2 epimerase K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008408 253.0
HKD1_k127_376039_3 protein required for cytochrome oxidase assembly K02259 - - 0.0000000000000000000000000001141 126.0
HKD1_k127_376039_4 Glycosyl transferase family 2 - - - 0.0000000000000000000000003463 109.0
HKD1_k127_376039_6 - - - - 0.00000000004706 74.0
HKD1_k127_3769956_0 COG0553 Superfamily II DNA RNA helicases, SNF2 family - - - 0.0 1074.0
HKD1_k127_3769956_1 ubiE/COQ5 methyltransferase family - - - 0.000000002953 64.0
HKD1_k127_3796563_0 Glycosyl hydrolases family 8 K00694 - 2.4.1.12 0.0 1135.0
HKD1_k127_3796563_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 402.0
HKD1_k127_3796563_2 PFAM Glutathione S-transferase domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000001203 241.0
HKD1_k127_3796563_3 Protein of unknown function (DUF2855) - - - 0.0000000000000000000000000000000000000000000000000000000000000000005264 235.0
HKD1_k127_383630_0 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 461.0
HKD1_k127_383630_1 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 346.0
HKD1_k127_383630_2 pfam abc K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004083 254.0
HKD1_k127_383630_3 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000005741 261.0
HKD1_k127_383630_4 ABC-2 type transporter K09694 - - 0.000000000000000000000000000000000000000000000000000008364 210.0
HKD1_k127_383630_5 Fis family transcriptional regulator - - - 0.000002835 59.0
HKD1_k127_383630_6 Methyltransferase type 11 - - - 0.00001303 50.0
HKD1_k127_383630_7 protein ubiquitination K01915,K09523,K09527,K10443,K13956 - 6.3.1.2 0.00001933 57.0
HKD1_k127_383630_8 peptidyl-tyrosine sulfation - - - 0.0000446 56.0
HKD1_k127_3844297_0 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008065 503.0
HKD1_k127_3844297_1 Protein of unknown function (DUF692) K09930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 317.0
HKD1_k127_3844297_2 DoxX - - - 0.0000000000000000000000000000000000000002737 164.0
HKD1_k127_3844297_3 DoxX-like family K15977 - - 0.000000000000000000000009013 108.0
HKD1_k127_3844297_4 ligase activity, forming nitrogen-metal bonds K02230 - 6.6.1.2 0.000000000000000000003651 93.0
HKD1_k127_3844297_5 Putative DNA-binding domain - - - 0.00006017 53.0
HKD1_k127_3853133_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 355.0
HKD1_k127_3853133_1 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006735 340.0
HKD1_k127_3853133_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 291.0
HKD1_k127_385795_0 ABC transporter K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008496 353.0
HKD1_k127_385795_1 Glycosyl transferase WecB/TagA/CpsF family K05946 - 2.4.1.187 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006534 308.0
HKD1_k127_385795_10 Methyltransferase FkbM domain - - - 0.000000000000000000000000000000000000000000000001734 183.0
HKD1_k127_385795_11 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000002013 149.0
HKD1_k127_385795_12 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000766 131.0
HKD1_k127_385795_2 Caenorhabditis protein of unknown function, DUF268 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002556 295.0
HKD1_k127_385795_3 PFAM Glycosyl transferase, family 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002741 289.0
HKD1_k127_385795_4 ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007968 289.0
HKD1_k127_385795_5 PFAM sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000121 268.0
HKD1_k127_385795_6 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001871 271.0
HKD1_k127_385795_7 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000003361 263.0
HKD1_k127_385795_8 TIGRFAM methyltransferase FkbM family - - - 0.0000000000000000000000000000000000000000000000000000000000000006729 230.0
HKD1_k127_385795_9 Glycosyl transferase family group 2 - - - 0.000000000000000000000000000000000000000000000000000000000000009326 229.0
HKD1_k127_3860513_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 5.737e-249 780.0
HKD1_k127_3860513_1 Thiol oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009764 452.0
HKD1_k127_3860513_10 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000375 102.0
HKD1_k127_3860513_2 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 420.0
HKD1_k127_3860513_3 cytochrome p450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001877 279.0
HKD1_k127_3860513_4 Steryl acetyl hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002255 283.0
HKD1_k127_3860513_5 Glutathione S-transferase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008618 261.0
HKD1_k127_3860513_6 EthD domain - - - 0.0000000000000000000000000000000000000000000000005546 184.0
HKD1_k127_3860513_7 YcdC-like protein, C-terminal region K09017 - - 0.0000000000000000000000000000000000000000000007175 173.0
HKD1_k127_3860513_8 Rdx family K07401 - - 0.000000000000000000000000000000000007179 153.0
HKD1_k127_3860513_9 SnoaL-like domain - - - 0.0000000000000000000000000000000004921 136.0
HKD1_k127_3862353_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1418.0
HKD1_k127_3862353_1 acyl-CoA dehydrogenase K20035 - - 0.00000000000000000000000000000000000000000000000000000000000000001613 241.0
HKD1_k127_3862353_2 Flavin-binding monooxygenase-like - - - 0.0000000000000000000000000000000000000000000000000000001352 203.0
HKD1_k127_3875851_0 Type II/IV secretion system protein K02454 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 559.0
HKD1_k127_390877_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 414.0
HKD1_k127_390877_1 DNA polymerase A domain K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000009978 263.0
HKD1_k127_390877_2 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.00000000000000000000000000000000000001162 153.0
HKD1_k127_390877_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000002254 95.0
HKD1_k127_390877_4 Bacterial regulatory proteins, tetR family - - - 0.0000000000000001511 94.0
HKD1_k127_3914183_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000003343 146.0
HKD1_k127_3950771_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009943 308.0
HKD1_k127_3950771_1 Belongs to the bacterial solute-binding protein 9 family K09815,K15727 - - 0.000001157 61.0
HKD1_k127_398560_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00819 - 2.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 604.0
HKD1_k127_398560_1 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 449.0
HKD1_k127_398560_2 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000003086 235.0
HKD1_k127_398560_3 proteins of the AP superfamily - - - 0.00000000000000000000000000000000000000000000006493 186.0
HKD1_k127_398560_4 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000669 177.0
HKD1_k127_3990277_0 COG0076 Glutamate decarboxylase and related PLP-dependent proteins K01634 - 4.1.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000451 468.0
HKD1_k127_3990277_1 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000003859 196.0
HKD1_k127_3990277_2 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000007825 200.0
HKD1_k127_3990277_3 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000833 179.0
HKD1_k127_3990277_4 AhpC/TSA family - - - 0.000000000000000000000000007197 113.0
HKD1_k127_3990277_5 - - - - 0.00000000000008175 76.0
HKD1_k127_4007415_0 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 476.0
HKD1_k127_4007415_1 methyltransferase - - - 0.000000000000000000000000000000000000000000000001298 182.0
HKD1_k127_4007415_2 ThiS family K03636 - - 0.00000000136 59.0
HKD1_k127_4016698_0 Aminotransferase class-III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 349.0
HKD1_k127_4016698_1 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006027 282.0
HKD1_k127_4016698_2 TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.0000000000000000000000000000000009686 142.0
HKD1_k127_4016698_3 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000004454 126.0
HKD1_k127_4016698_4 TIGRFAM Protein of - - - 0.000000000000000000000000004619 129.0
HKD1_k127_4024805_0 dna ligase - - - 1.575e-219 687.0
HKD1_k127_4024805_1 - - - - 0.000000000356 65.0
HKD1_k127_4024805_2 belongs to the sigma-70 factor family K03088 - - 0.000000003651 59.0
HKD1_k127_4030063_0 sulfate adenylyltransferase K00958 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 476.0
HKD1_k127_4030063_1 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005103 424.0
HKD1_k127_4030063_2 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00000000000000000000000000000000001504 143.0
HKD1_k127_4030063_3 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000001705 110.0
HKD1_k127_4030063_4 Transcriptional regulator - - - 0.000000000000000000009915 103.0
HKD1_k127_4030063_5 Amidohydrolase family - - - 0.0000001201 64.0
HKD1_k127_4030063_6 JAB/MPN domain - - - 0.00007518 53.0
HKD1_k127_4041754_0 regulation of DNA-templated transcription, elongation - - - 5.146e-252 813.0
HKD1_k127_4041754_1 methyltransferase activity K00213,K00222 - 1.3.1.21,1.3.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 472.0
HKD1_k127_4041754_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 312.0
HKD1_k127_4041754_3 Glycine-zipper domain - - - 0.0000000000000000000000000000000000008473 143.0
HKD1_k127_4041754_4 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 K18586 - - 0.000000000000000000000000000004879 138.0
HKD1_k127_4041754_5 ubiquitin - - - 0.000000000000000002877 98.0
HKD1_k127_4041754_6 Bacterial regulatory proteins, tetR family - - - 0.00000007411 64.0
HKD1_k127_4041754_7 - - - - 0.000004721 57.0
HKD1_k127_4041754_8 short-chain dehydrogenase - - - 0.0002177 44.0
HKD1_k127_4045974_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 4.054e-209 659.0
HKD1_k127_4045974_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199 464.0
HKD1_k127_4045974_10 Flavin reductase like domain - - - 0.0000000000000000000000000000000007966 142.0
HKD1_k127_4045974_11 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.00000000000000000000000000000001699 139.0
HKD1_k127_4045974_12 PFAM Preprotein translocase SecG subunit K03075 - - 0.00000000000003033 87.0
HKD1_k127_4045974_13 Thioredoxin - - - 0.000000000368 69.0
HKD1_k127_4045974_2 Fructose-bisphosphate aldolase class-I K01623 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004598 455.0
HKD1_k127_4045974_3 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 412.0
HKD1_k127_4045974_4 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 337.0
HKD1_k127_4045974_5 penicillin amidase K01434 - 3.5.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 316.0
HKD1_k127_4045974_6 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001815 284.0
HKD1_k127_4045974_7 PFAM OmpA MotB domain protein K02557 - - 0.00000000000000000000000000000000000000000000544 175.0
HKD1_k127_4045974_8 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 - 2.7.7.7 0.000000000000000000000000000000000000000008728 169.0
HKD1_k127_4045974_9 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.00000000000000000000000000000000000000007863 153.0
HKD1_k127_405199_0 oxidoreductase activity K07114 - - 0.0000000000000000000000000000000000000000000000000000005861 211.0
HKD1_k127_405199_1 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000005453 154.0
HKD1_k127_405199_2 PFAM PspA IM30 family K03969 - - 0.00004165 46.0
HKD1_k127_406118_0 DEAD DEAH box K03724 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002905 282.0
HKD1_k127_406118_1 PRC-barrel domain - - - 0.00000000000000000000000000000000000000002851 155.0
HKD1_k127_406118_2 - - - - 0.000000000000000008646 87.0
HKD1_k127_406118_3 Protein involved in biological_process - - - 0.0000005668 61.0
HKD1_k127_406118_4 Dienelactone hydrolase family - - - 0.000002461 60.0
HKD1_k127_4079624_0 PFAM 4-hydroxyphenylacetate 3-hydroxylase K00483,K21726 - 1.14.13.166,1.14.13.29,1.14.14.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000739 600.0
HKD1_k127_4079624_1 taurine catabolism dioxygenase K22303 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016705,GO:0016706,GO:0051213,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007659 334.0
HKD1_k127_4079624_2 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000001047 237.0
HKD1_k127_4079624_3 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000009881 194.0
HKD1_k127_4079624_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000005489 187.0
HKD1_k127_4079624_5 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000009292 173.0
HKD1_k127_4079624_6 COG0845 Membrane-fusion protein K01993 - - 0.00000000000000000005224 102.0
HKD1_k127_4079624_7 Transcriptional regulator TetR - - - 0.00000000000000003943 90.0
HKD1_k127_4079624_8 corticotropin-releasing factor - - - 0.0000000004297 74.0
HKD1_k127_4086244_0 Iron-containing alcohol dehydrogenase K19955 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004155 559.0
HKD1_k127_4086244_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 338.0
HKD1_k127_4086244_2 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K07106,K09001 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 2.7.1.170,4.2.1.126 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 298.0
HKD1_k127_4086244_3 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007373 261.0
HKD1_k127_4086244_4 membrane protein, required for spore maturation in B.subtilis - - - 0.0000000000000000000000000000000000000000000000000003586 189.0
HKD1_k127_4086244_5 Nucleotidyl transferase K00966,K16881 - 2.7.7.13,5.4.2.8 0.00000000000000000000000000000000000000000000000007247 196.0
HKD1_k127_4086244_6 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000001818 184.0
HKD1_k127_4086244_7 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.0000000000000000000004159 111.0
HKD1_k127_4090449_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 3.488e-276 872.0
HKD1_k127_4090449_1 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009014 443.0
HKD1_k127_4090449_2 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000001958 202.0
HKD1_k127_4090449_3 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000000000000000000000007922 158.0
HKD1_k127_4090449_4 protein heterodimerization activity - - - 0.00000000000000000000000000000000000007313 165.0
HKD1_k127_4090449_5 methyltransferase activity - - - 0.000000000000000000000000000000000003928 151.0
HKD1_k127_4090449_6 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000013 149.0
HKD1_k127_411889_0 arylsulfatase activity K01133 - 3.1.6.6 0.0000000000000000000000000000000000000000000000000000000000007249 228.0
HKD1_k127_4125384_0 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 454.0
HKD1_k127_4125384_1 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000001231 143.0
HKD1_k127_4125384_2 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000008267 111.0
HKD1_k127_4125877_0 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 310.0
HKD1_k127_4125877_1 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000002004 132.0
HKD1_k127_4125877_2 oligosaccharyl transferase activity - - - 0.00000001291 61.0
HKD1_k127_4130883_0 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006794 633.0
HKD1_k127_4130883_1 Belongs to the GST superfamily K11209 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 417.0
HKD1_k127_4130883_10 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000001489 86.0
HKD1_k127_4130883_11 - - - - 0.000005354 55.0
HKD1_k127_4130883_12 COG3267 Type II secretory pathway, component ExeA K02450 - - 0.00006118 56.0
HKD1_k127_4130883_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 364.0
HKD1_k127_4130883_3 Belongs to the short-chain dehydrogenases reductases (SDR) family K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006503 298.0
HKD1_k127_4130883_4 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.0000000000000000000000000000000000000000000000000000001302 201.0
HKD1_k127_4130883_5 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 0.000000000000000000000000000000000000002351 157.0
HKD1_k127_4130883_6 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000005575 143.0
HKD1_k127_4130883_7 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000000000000002225 139.0
HKD1_k127_4130883_8 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000403 104.0
HKD1_k127_4130883_9 - - - - 0.000000000000000000000172 104.0
HKD1_k127_4139075_0 converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA - - - 3.73e-224 708.0
HKD1_k127_4139075_1 CoA-transferase family III K07544 - 2.8.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 395.0
HKD1_k127_4139075_2 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 320.0
HKD1_k127_4139075_3 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000004039 277.0
HKD1_k127_4139075_4 COG3663 G T U mismatch-specific DNA glycosylase K03649 - 3.2.2.28 0.0000000000000000000000000000000000000000000000000002912 189.0
HKD1_k127_4139075_5 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000001739 153.0
HKD1_k127_4139075_6 - - - - 0.0000000000001008 83.0
HKD1_k127_4139075_8 Methyltransferase - - - 0.0008175 45.0
HKD1_k127_4143655_0 ABC-type multidrug transport system, ATPase component K13926 - - 0.0 1142.0
HKD1_k127_4143655_1 COG0367 Asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008869 619.0
HKD1_k127_4143655_10 COG2010 Cytochrome c, mono- and diheme variants - - - 0.000000000000000000000008652 106.0
HKD1_k127_4143655_11 synthetase K18688 - 6.2.1.42 0.0000000000001162 72.0
HKD1_k127_4143655_12 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000002613 56.0
HKD1_k127_4143655_2 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008817 571.0
HKD1_k127_4143655_3 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007107 556.0
HKD1_k127_4143655_4 alcohol dehydrogenase K18369 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 546.0
HKD1_k127_4143655_5 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 457.0
HKD1_k127_4143655_6 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006304 328.0
HKD1_k127_4143655_7 secretion protein K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003061 302.0
HKD1_k127_4143655_8 Male sterility protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002125 266.0
HKD1_k127_4143655_9 Domain of unknown function (DUF4142) K08995 - - 0.00000000000000000000000000000000000000000000000000000000001914 209.0
HKD1_k127_4160621_0 ribonucleoside-diphosphate reductase activity K00525 - 1.17.4.1 0.0 1191.0
HKD1_k127_4160621_1 M18 family aminopeptidase K01267 - 3.4.11.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 486.0
HKD1_k127_4160621_2 acyl-CoA dehydrogenase K14448 - 1.3.8.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 400.0
HKD1_k127_4160621_3 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 297.0
HKD1_k127_4160621_4 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000007804 177.0
HKD1_k127_4160621_5 inositol monophosphate 1-phosphatase activity K01092,K05602,K18649 - 3.1.3.15,3.1.3.25,3.1.3.93 0.000000000000000000000000000000000000000000004353 178.0
HKD1_k127_4160621_6 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP - - - 0.0000000000000000000000003558 108.0
HKD1_k127_4160621_7 eight transmembrane protein EpsH - - - 0.0000000000000000003787 102.0
HKD1_k127_4160621_8 Large extracellular alpha-helical protein - - - 0.00000000000001351 79.0
HKD1_k127_4160621_9 - - - - 0.0000006745 57.0
HKD1_k127_4169206_0 heme-copper terminal oxidase activity K02274 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 611.0
HKD1_k127_4169206_1 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 325.0
HKD1_k127_4169206_10 electron transport protein SCO1 SenC K07152 - - 0.000000000002872 81.0
HKD1_k127_4169206_11 - - - - 0.000000001181 72.0
HKD1_k127_4169206_2 Male sterility protein K00091,K19997 - 1.1.1.219,5.1.3.26 0.000000000000000000000000000000000000000000000000000000000000000000000001652 257.0
HKD1_k127_4169206_3 Methyl-viologen-reducing hydrogenase, delta subunit K02572,K02573,K03522 - - 0.0000000000000000000000000000000000000000000000000000000000008844 237.0
HKD1_k127_4169206_4 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000007966 209.0
HKD1_k127_4169206_5 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000000000008471 162.0
HKD1_k127_4169206_6 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000001734 120.0
HKD1_k127_4169206_7 Domain of unknown function (DUF374) K09778 - - 0.0000000000000000000000006867 115.0
HKD1_k127_4169206_8 inorganic diphosphatase activity K05521 - 3.2.2.24 0.000000000000000000000006347 114.0
HKD1_k127_4169206_9 Protein of unknown function (DUF4242) - - - 0.000000000001221 72.0
HKD1_k127_4180667_0 6-phosphogluconolactonase activity - - - 0.0 1061.0
HKD1_k127_4180667_1 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 531.0
HKD1_k127_4180667_10 tetR family - - - 0.000000000000002123 86.0
HKD1_k127_4180667_11 cellulose binding - - - 0.0000000000006422 78.0
HKD1_k127_4180667_12 CoA-transferase family III - - - 0.00000000002528 64.0
HKD1_k127_4180667_13 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00004913 56.0
HKD1_k127_4180667_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 361.0
HKD1_k127_4180667_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 353.0
HKD1_k127_4180667_4 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006052 313.0
HKD1_k127_4180667_5 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002482 285.0
HKD1_k127_4180667_6 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001261 261.0
HKD1_k127_4180667_7 PFAM transcriptional regulator domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000001991 229.0
HKD1_k127_4180667_8 Peptidyl-prolyl cis-trans K03772,K03773 - 5.2.1.8 0.00000000000000000000000000000000000000000000006755 178.0
HKD1_k127_4180667_9 YMGG-like Gly-zipper - - - 0.00000000000000000000000008187 116.0
HKD1_k127_4198589_0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain K00261,K00262 - 1.4.1.3,1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 515.0
HKD1_k127_4198589_1 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 375.0
HKD1_k127_4198589_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 324.0
HKD1_k127_4198589_3 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007521 302.0
HKD1_k127_4198589_4 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935,K02169 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197,6.3.3.3 0.0000000000000000000001394 100.0
HKD1_k127_4215747_0 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007124 359.0
HKD1_k127_4215747_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 296.0
HKD1_k127_4215747_10 peptidase M48, Ste24p - - - 0.000000000000000000000000000000000275 149.0
HKD1_k127_4215747_11 Tetratricopeptide repeat - - - 0.000000000000000000000000000000001425 140.0
HKD1_k127_4215747_12 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000001982 143.0
HKD1_k127_4215747_13 DivIVA protein K04074 - - 0.000000000000000000002287 101.0
HKD1_k127_4215747_14 Uncharacterized conserved protein (DUF2203) - - - 0.00000000000000001695 95.0
HKD1_k127_4215747_15 Putative regulatory protein - - - 0.0000000000000002752 85.0
HKD1_k127_4215747_16 Belongs to the P-Pant transferase superfamily - - - 0.00000000000005779 75.0
HKD1_k127_4215747_2 Glutathione-dependent formaldehyde-activating enzyme K03396 - 4.4.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002145 274.0
HKD1_k127_4215747_3 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002787 258.0
HKD1_k127_4215747_4 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000008968 241.0
HKD1_k127_4215747_5 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000002161 234.0
HKD1_k127_4215747_6 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000001685 216.0
HKD1_k127_4215747_7 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.000000000000000000000000000000000000000000000000002761 196.0
HKD1_k127_4215747_8 YCII-related domain - - - 0.00000000000000000000000000000000000000000000001115 175.0
HKD1_k127_4215747_9 PFAM Maf family protein K06287 - - 0.000000000000000000000000000000000000000000001237 172.0
HKD1_k127_4225482_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 462.0
HKD1_k127_4225482_1 Belongs to the CarA family K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 452.0
HKD1_k127_4225482_2 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 378.0
HKD1_k127_4225482_3 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000002509 192.0
HKD1_k127_4225482_4 Belongs to the CarB family K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000002871 167.0
HKD1_k127_4225482_5 HAF family - - - 0.00001215 56.0
HKD1_k127_424179_0 6-phosphogluconolactonase activity - - - 3.053e-267 854.0
HKD1_k127_424179_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 399.0
HKD1_k127_4291439_0 Sir2 family K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 301.0
HKD1_k127_4291439_1 COG2365 Protein tyrosine serine phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000003686 227.0
HKD1_k127_4291439_2 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.000000000000000000000000000000000000000000005085 177.0
HKD1_k127_4291439_3 COG0760 Parvulin-like peptidyl-prolyl isomerase - - - 0.000000000000000000000000000000000000011 159.0
HKD1_k127_4291439_4 - - - - 0.000000000000000000000000000001295 127.0
HKD1_k127_4291439_5 Bacterial transcriptional repressor C-terminal - - - 0.0000000001698 70.0
HKD1_k127_4291439_6 lipolytic protein G-D-S-L family - - - 0.000002644 60.0
HKD1_k127_4298316_0 oligoendopeptidase F K08602 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 506.0
HKD1_k127_4298316_1 protoporphyrinogen oxidase activity K00231 - 1.3.3.15,1.3.3.4 0.00000000000000001569 96.0
HKD1_k127_4298316_2 Bacterial DNA polymerase III alpha subunit K02337,K14162 - 2.7.7.7 0.000000000000007829 88.0
HKD1_k127_4298316_3 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000004114 58.0
HKD1_k127_42986_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 413.0
HKD1_k127_42986_1 Belongs to the TPP enzyme family K01568,K04103 - 4.1.1.1,4.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 343.0
HKD1_k127_42986_2 Predicted membrane protein (DUF2238) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 310.0
HKD1_k127_42986_3 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.00000000000000000000000000000000000000000000000001874 188.0
HKD1_k127_42986_4 sirohydrochlorin ferrochelatase K03794 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009058,GO:0009507,GO:0009536,GO:0009987,GO:0016829,GO:0018130,GO:0019354,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046156,GO:0046483,GO:0048037,GO:0050896,GO:0051186,GO:0051188,GO:0051266,GO:0051536,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.4 0.000000000000000000000007162 105.0
HKD1_k127_42986_5 Domain of unknown function (DUF4445) - - - 0.0000001286 64.0
HKD1_k127_42986_6 COG4235 Cytochrome c biogenesis factor K02200 - - 0.0000001404 63.0
HKD1_k127_4317592_0 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 435.0
HKD1_k127_4317592_1 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 400.0
HKD1_k127_4317592_10 phage shock protein A, PspA K03969 - - 0.000000000000000000000000151 119.0
HKD1_k127_4317592_11 Protein of unknown function (DUF3309) - - - 0.0000000000000000001282 90.0
HKD1_k127_4317592_2 phosphoserine phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 383.0
HKD1_k127_4317592_3 pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 298.0
HKD1_k127_4317592_4 - - - - 0.00000000000000000000000000000000000000000000000000000001592 212.0
HKD1_k127_4317592_5 acetyltransferase - - - 0.0000000000000000000000000000000000000000006412 168.0
HKD1_k127_4317592_6 Belongs to the UPF0178 family K09768 - - 0.000000000000000000000000000000000000000006781 175.0
HKD1_k127_4317592_7 Histidine kinase K07709,K10942 - 2.7.13.3 0.00000000000000000000000000000000003798 151.0
HKD1_k127_4317592_8 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000006615 146.0
HKD1_k127_4317592_9 Histidine kinase HAMP K02482 - 2.7.13.3 0.000000000000000000000000000005596 138.0
HKD1_k127_4326991_0 Pfam Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 608.0
HKD1_k127_4326991_1 PFAM Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 482.0
HKD1_k127_4326991_2 PFAM amidohydrolase 2 K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 458.0
HKD1_k127_4326991_3 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005645 355.0
HKD1_k127_4326991_4 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 327.0
HKD1_k127_4326991_5 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 342.0
HKD1_k127_4326991_6 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000005526 251.0
HKD1_k127_4326991_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K19595 - - 0.000000000000000000000000000000002704 150.0
HKD1_k127_4326991_8 - - - - 0.00000000000000000000000005517 124.0
HKD1_k127_4329409_0 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 312.0
HKD1_k127_4329409_1 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002897 280.0
HKD1_k127_4329409_2 NAD dependent epimerase/dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000007805 231.0
HKD1_k127_4329409_3 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000008871 198.0
HKD1_k127_4329409_4 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.0000000000000000000000000000000055 136.0
HKD1_k127_4331502_0 dihydrodipicolinate reductase K21672 - 1.4.1.12,1.4.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 494.0
HKD1_k127_4331502_1 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 312.0
HKD1_k127_4331502_2 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.0000000000000000000000000007444 119.0
HKD1_k127_4331502_3 Sodium hydrogen exchanger - - - 0.000000004008 63.0
HKD1_k127_4345572_0 Two component transcriptional regulator, winged helix family K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004039 264.0
HKD1_k127_4345572_1 COG3209 Rhs family protein - - - 0.0000000000000000000000000002319 134.0
HKD1_k127_4345572_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07636 - 2.7.13.3 0.000000000000000000000002109 114.0
HKD1_k127_4349405_0 Belongs to the DEAD box helicase family K03732,K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000668 390.0
HKD1_k127_4349405_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000002232 118.0
HKD1_k127_4349405_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000001633 87.0
HKD1_k127_4349405_3 ABC transporter transmembrane region K06147 - - 0.0003277 52.0
HKD1_k127_4349711_0 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 519.0
HKD1_k127_4349711_1 Protein of unknown function (DUF2961) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 395.0
HKD1_k127_4349711_2 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000007169 239.0
HKD1_k127_4349711_4 Divergent 4Fe-4S mono-cluster - - - 0.000000000001819 81.0
HKD1_k127_4349711_5 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain K02488 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 0.00002599 49.0
HKD1_k127_4368885_0 TIGRFAM TraB family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007826 420.0
HKD1_k127_4368885_1 Putative cyclase K07130 GO:0003674,GO:0003824,GO:0004061,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006208 294.0
HKD1_k127_4368885_2 Cytochrome P450 K05917 GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0008150,GO:0008152,GO:0008202,GO:0008398,GO:0016125,GO:0016491,GO:0016705,GO:0016709,GO:0020037,GO:0032451,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046906,GO:0048037,GO:0055114,GO:0070988,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901615 1.14.13.70 0.000000000000000000000000000000000000000000000000000000000000000000000000009612 256.0
HKD1_k127_4368885_3 Hsp33 protein K04083 - - 0.00000000000000000000000000000000000000000000000000002773 215.0
HKD1_k127_4368885_4 Glycosyl transferase 4-like - - - 0.00000000008253 75.0
HKD1_k127_4371497_0 Squalene-hopene cyclase N-terminal domain K06045 - 4.2.1.129,5.4.99.17 3.287e-257 832.0
HKD1_k127_4371497_1 Lipase maturation factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 651.0
HKD1_k127_4371497_2 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 511.0
HKD1_k127_4371497_3 TIGRFAM squalene-associated FAD-dependent desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 401.0
HKD1_k127_4371497_4 polysaccharide catabolic process K05991 - 3.2.1.123 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000635 284.0
HKD1_k127_4371497_5 PFAM Squalene phytoene synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001156 260.0
HKD1_k127_4371497_6 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000001409 234.0
HKD1_k127_4371497_7 Bacterial regulatory proteins, tetR family - - - 0.00000000007223 74.0
HKD1_k127_4372690_0 cytochrome p450 K16046 - 1.14.13.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002998 283.0
HKD1_k127_4372690_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000000000000000000001111 175.0
HKD1_k127_4372690_2 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000002473 141.0
HKD1_k127_4372690_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000001456 137.0
HKD1_k127_4372690_4 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000003021 121.0
HKD1_k127_4372690_5 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006015,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042301,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046391,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 0.00000000000000001129 87.0
HKD1_k127_4372690_6 Domain of unknown function (DUF1844) - - - 0.000000000000000344 89.0
HKD1_k127_4379_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 638.0
HKD1_k127_4379_1 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 542.0
HKD1_k127_4379_10 ThiS family K03636 - - 0.0000000000000000000001193 113.0
HKD1_k127_4379_11 SnoaL-like domain - - - 0.000000000000000005404 98.0
HKD1_k127_4379_12 Kdo2-lipid A biosynthetic process K02517,K20543,K22311 - 2.3.1.241,2.3.1.265 0.000000000000009426 89.0
HKD1_k127_4379_13 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000001525 71.0
HKD1_k127_4379_14 Periplasmic or secreted lipoprotein - - - 0.000003982 53.0
HKD1_k127_4379_2 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005243 406.0
HKD1_k127_4379_3 Alcohol dehydrogenase GroES-like domain K00004 - 1.1.1.303,1.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 328.0
HKD1_k127_4379_4 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003735 304.0
HKD1_k127_4379_5 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009441 275.0
HKD1_k127_4379_6 alpha/beta hydrolase fold K01066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001756 267.0
HKD1_k127_4379_7 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000378 171.0
HKD1_k127_4379_8 Acyl-CoA thioesterase K10805 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016042,GO:0016054,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042802,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072329,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901575 - 0.0000000000000000000000001121 120.0
HKD1_k127_4379_9 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000006003 121.0
HKD1_k127_4400629_0 dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 544.0
HKD1_k127_4400629_1 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005875 327.0
HKD1_k127_4400629_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000002119 182.0
HKD1_k127_4400629_3 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000005349 173.0
HKD1_k127_4400629_4 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.0000000000000000000000000000000000000002483 152.0
HKD1_k127_4400629_5 Protein of unknown function (DUF4242) - - - 0.00000000000000000000000000001546 126.0
HKD1_k127_4400629_6 dihydrodipicolinate reductase K21672 - 1.4.1.12,1.4.1.26 0.0000000000000000000000000003087 116.0
HKD1_k127_4406149_0 Belongs to the glycosyl hydrolase 13 family K01200,K01214 - 3.2.1.41,3.2.1.68 2.254e-209 684.0
HKD1_k127_4406149_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000005564 262.0
HKD1_k127_4406149_2 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000001832 263.0
HKD1_k127_4433291_0 PFAM phosphate acetyl butaryl transferase K00625,K00634 - 2.3.1.19,2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008119 441.0
HKD1_k127_4433291_1 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 331.0
HKD1_k127_4433291_2 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000002207 244.0
HKD1_k127_4433291_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000002862 250.0
HKD1_k127_4433291_4 B12 binding domain - - - 0.00000000000000000000000000000000000000233 165.0
HKD1_k127_4433291_6 - - - - 0.000000000000000000000003722 110.0
HKD1_k127_4434981_0 glycosyl transferase family 8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 407.0
HKD1_k127_4434981_1 glycosyl transferase family 8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005027 420.0
HKD1_k127_4434981_2 Sulfotransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006066 381.0
HKD1_k127_4434981_3 Nucleoside-diphosphate-sugar epimerase K07276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 353.0
HKD1_k127_4434981_4 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 310.0
HKD1_k127_4434981_5 ABC transporter transmembrane region K06148 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006123 256.0
HKD1_k127_4434981_6 Permease YjgP YjgQ family protein K07091,K11720 - - 0.000000000000000000000000000001047 141.0
HKD1_k127_4434981_7 Sulfotransferase family - - - 0.000003715 59.0
HKD1_k127_4448622_0 transcription factor binding K15836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006729 570.0
HKD1_k127_4448622_1 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000958 306.0
HKD1_k127_4459504_0 Ferrous iron transport protein B C terminus K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 603.0
HKD1_k127_4459504_1 Cystathionine gamma-synthase K01739 GO:0000096,GO:0000097,GO:0001887,GO:0003674,GO:0003824,GO:0003962,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003509 445.0
HKD1_k127_4459504_10 ASPIC and UnbV - - - 0.000006315 55.0
HKD1_k127_4459504_2 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 323.0
HKD1_k127_4459504_3 lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.0000000000000000000000000000000000000000005072 167.0
HKD1_k127_4459504_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335,K18331 - 1.12.1.3,1.6.5.3 0.0000000000000000000000000000000000000004083 152.0
HKD1_k127_4459504_5 NADH dehydrogenase (ubiquinone) activity K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.3 0.0000000000000000000000000000000001519 137.0
HKD1_k127_4459504_6 2 iron, 2 sulfur cluster binding K00334,K00335 - 1.6.5.3 0.0000000000000000000000000001499 133.0
HKD1_k127_4459504_7 6-phosphogluconolactonase activity - - - 0.000000000000000009377 91.0
HKD1_k127_4459504_8 COG1918 Fe2 transport system protein A K04758 - - 0.0000000000000092 77.0
HKD1_k127_4459504_9 - - - - 0.000000204 62.0
HKD1_k127_4500603_0 PQQ enzyme repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 548.0
HKD1_k127_4500603_1 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 416.0
HKD1_k127_4500603_2 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000001393 245.0
HKD1_k127_4500603_3 SWIM zinc finger - - - 0.000000000000000000000000000000000000000000000000000000000001638 225.0
HKD1_k127_4500603_4 - - - - 0.0000000000000000000000000000000000000000002635 175.0
HKD1_k127_4500603_5 - - - - 0.0000000000000000000000000000000000000005837 162.0
HKD1_k127_4500603_6 Transcription elongation factor, GreA/GreB, C-term K04760 - - 0.00000000000000000000000000000000001536 143.0
HKD1_k127_4500603_7 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000000000000000000000000000000001313 132.0
HKD1_k127_4500603_8 PFAM GCN5-related N-acetyltransferase - - - 0.000000008558 64.0
HKD1_k127_4500603_9 - - - - 0.0000002486 63.0
HKD1_k127_4502069_0 Molybdopterin oxidoreductase Fe4S4 domain K08357 - - 0.0000000000000000000000000000000000000000000000000000003727 207.0
HKD1_k127_4502069_1 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000001217 147.0
HKD1_k127_4502069_2 PFAM acyl-CoA dehydrogenase domain protein - - - 0.00000000000000000000000000002328 124.0
HKD1_k127_4517083_0 AMP-binding enzyme K02182 - 6.2.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 583.0
HKD1_k127_4517083_1 Belongs to the GST superfamily K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 295.0
HKD1_k127_4517083_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000000000000000000000000000000000000000000000002796 218.0
HKD1_k127_4517083_3 NfeD-like C-terminal, partner-binding - - - 0.0000000000000009831 88.0
HKD1_k127_4517083_4 Glycosyltransferase family 28 N-terminal domain K16444 - 2.4.1.310 0.0000000000006607 71.0
HKD1_k127_45223_0 Zinc-binding dehydrogenase K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 427.0
HKD1_k127_45223_1 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004516 242.0
HKD1_k127_4525556_0 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 331.0
HKD1_k127_4525556_1 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 324.0
HKD1_k127_4525556_2 Alanine-glyoxylate amino-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000001592 226.0
HKD1_k127_4525556_3 AraC family - - - 0.000000000000000000000000000000002659 141.0
HKD1_k127_4525556_4 - - - - 0.0000000000000000000000004828 119.0
HKD1_k127_4525556_5 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000001161 97.0
HKD1_k127_4528808_0 aconitate hydratase - - - 8.208e-310 967.0
HKD1_k127_4528808_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 372.0
HKD1_k127_4531475_0 Luciferase-like monooxygenase - - - 5.088e-210 659.0
HKD1_k127_4531475_1 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 506.0
HKD1_k127_4531475_10 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain - - - 0.00000000000000000000000000001106 131.0
HKD1_k127_4531475_11 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000004278 122.0
HKD1_k127_4531475_2 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 494.0
HKD1_k127_4531475_3 Ferric reductase NAD binding domain K02613,K15983 - 1.14.13.142 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 346.0
HKD1_k127_4531475_4 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 325.0
HKD1_k127_4531475_5 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 303.0
HKD1_k127_4531475_6 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000000000000000000000000000000000000000000000000000002718 256.0
HKD1_k127_4531475_7 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000008551 242.0
HKD1_k127_4531475_8 PFAM Phosphoglycerate mutase - - - 0.00000000000000000000000000000000000001207 162.0
HKD1_k127_4531475_9 Limonene-1,2-epoxide hydrolase catalytic domain K10533 - 3.3.2.8 0.00000000000000000000000000000001501 130.0
HKD1_k127_4537459_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004957 542.0
HKD1_k127_4537459_1 PFAM ABC transporter K02471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 544.0
HKD1_k127_4537459_11 pfam abc1 - - - 0.0000000815 54.0
HKD1_k127_4537459_2 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000791 466.0
HKD1_k127_4537459_3 Serine aminopeptidase, S33 K00433 - 1.11.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 441.0
HKD1_k127_4537459_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006807 358.0
HKD1_k127_4537459_5 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 330.0
HKD1_k127_4537459_6 Ferritin-like domain K04047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001423 264.0
HKD1_k127_4537459_7 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K00851,K00852,K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 2.7.1.12,2.7.1.15,5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000003379 233.0
HKD1_k127_4537459_8 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.00000000000000000000000000000000000000000000000002706 207.0
HKD1_k127_4537459_9 - - - - 0.000000000000000000211 95.0
HKD1_k127_4538094_0 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007158 421.0
HKD1_k127_4538094_1 PFAM ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 378.0
HKD1_k127_4538094_2 multidrug resistance efflux pump K01993 - - 0.000000000000000000000000000000000000000000000000000000000001403 229.0
HKD1_k127_4538094_3 transcriptional regulator - - - 0.000000000000000000000000000005052 126.0
HKD1_k127_4538094_4 Heavy metal translocating P-type atpase K17686 - 3.6.3.54 0.000000003542 58.0
HKD1_k127_4538094_5 Hemerythrin HHE - - - 0.0001137 51.0
HKD1_k127_454731_0 Flavoprotein involved in K transport K03379 - 1.14.13.22 4.09e-293 910.0
HKD1_k127_454731_1 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 427.0
HKD1_k127_454731_2 oligopeptide transporter, OPT family - - - 0.00000000000000000000000000000000000000004763 158.0
HKD1_k127_4556618_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006113 454.0
HKD1_k127_4556618_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 376.0
HKD1_k127_4556618_2 coenzyme F390 K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000179 238.0
HKD1_k127_4556618_3 Protein of unknown function (DUF3485) - - - 0.00000000000000000000000000000002358 134.0
HKD1_k127_4557471_0 COG0439 Biotin carboxylase - - - 1.61e-273 869.0
HKD1_k127_4557471_1 CoA carboxylase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000003705 230.0
HKD1_k127_4557471_2 Sulfatase K01133 - 3.1.6.6 0.0000000000000000000000000000000000000000000002034 184.0
HKD1_k127_4557471_3 COG0457 FOG TPR repeat - - - 0.0000000002885 72.0
HKD1_k127_4570904_0 MMPL family K06994,K20470 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 365.0
HKD1_k127_463366_0 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 387.0
HKD1_k127_463366_1 PFAM Glycosyl transferase family 2 K10012,K20534 - 2.4.2.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000007278 284.0
HKD1_k127_463366_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000001098 81.0
HKD1_k127_4652494_0 Belongs to the GPAT DAPAT family K00631 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 542.0
HKD1_k127_4652494_1 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 344.0
HKD1_k127_4652494_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000273 181.0
HKD1_k127_4652494_3 - - - - 0.00000000000000000000000000003563 133.0
HKD1_k127_4652494_4 Alpha/beta hydrolase family - - - 0.0000000006061 59.0
HKD1_k127_4657409_0 PA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 541.0
HKD1_k127_4657409_1 Polynucleotide adenylyltransferase K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 357.0
HKD1_k127_4657409_2 - - - - 0.000000000000000000000000000000000000004964 162.0
HKD1_k127_4657409_3 FR47-like protein - - - 0.000000000000000000000000000000000000007632 163.0
HKD1_k127_4657409_4 negative regulation of translational initiation - - - 0.0000000000000005396 86.0
HKD1_k127_4657409_5 Belongs to the ompA family - - - 0.000000000000001249 88.0
HKD1_k127_4657409_6 HlyD family secretion protein K02005 - - 0.0002596 53.0
HKD1_k127_4661485_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008129 491.0
HKD1_k127_4661485_1 COGs COG4299 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007216 411.0
HKD1_k127_4661485_2 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009616 396.0
HKD1_k127_4661485_3 Acyl-CoA dehydrogenase, C-terminal domain K16047 GO:0000166,GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006066,GO:0006629,GO:0006694,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008610,GO:0009056,GO:0009058,GO:0016020,GO:0016042,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016712,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044110,GO:0044116,GO:0044117,GO:0044238,GO:0044281,GO:0044282,GO:0044403,GO:0044419,GO:0044464,GO:0046164,GO:0048037,GO:0050660,GO:0050662,GO:0051704,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:1901265,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1902652 1.14.14.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 401.0
HKD1_k127_4661485_4 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005221 327.0
HKD1_k127_4661485_5 Amidohydrolase K22213 - 4.1.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007736 306.0
HKD1_k127_4661485_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001276 285.0
HKD1_k127_4661485_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003578 266.0
HKD1_k127_4661485_8 COG3000 Sterol desaturase - - - 0.000000000000000000000000000000000000000000000000000009656 199.0
HKD1_k127_4661485_9 tetR family - - - 0.0000000000000000000000005201 119.0
HKD1_k127_4687797_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008822 563.0
HKD1_k127_4687797_1 MutS domain I K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 328.0
HKD1_k127_4687797_2 TIGRFAM Tyrosine recombinase XerD K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001562 268.0
HKD1_k127_4687797_3 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000003375 260.0
HKD1_k127_4687797_4 Belongs to the tRNA nucleotidyltransferase poly(A) polymerase family K00974 - 2.7.7.72 0.00000000000000000000000000000000003703 153.0
HKD1_k127_4697397_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000000000000000000003727 220.0
HKD1_k127_4697397_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.00000000000000000000000000000004606 138.0
HKD1_k127_4700892_0 Aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006499 617.0
HKD1_k127_4700892_1 MotA/TolQ/ExbB proton channel family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 430.0
HKD1_k127_4700892_2 MotA/TolQ/ExbB proton channel family - - - 0.000000000000000000000000000000000000000000000000000000000003639 214.0
HKD1_k127_4700892_3 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000000000000000000000006229 175.0
HKD1_k127_4700892_4 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000005669 169.0
HKD1_k127_4700892_5 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000666 172.0
HKD1_k127_4700892_6 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000000000000000000000000000000006252 138.0
HKD1_k127_4700892_7 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000000000001245 151.0
HKD1_k127_4700892_8 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000000000000001108 109.0
HKD1_k127_4700892_9 Ferredoxin oxidoreductase K00175 - 1.2.7.11,1.2.7.3 0.0000000000004479 70.0
HKD1_k127_4708459_0 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000002297 208.0
HKD1_k127_4708459_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000001742 148.0
HKD1_k127_4708459_2 PilZ domain - - - 0.0000000000000000000000000000000000165 146.0
HKD1_k127_4708459_3 - - - - 0.0000002563 53.0
HKD1_k127_4708459_4 - - - - 0.00001654 53.0
HKD1_k127_4717703_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 1.044e-231 730.0
HKD1_k127_4717703_1 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005088 391.0
HKD1_k127_4717703_2 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 324.0
HKD1_k127_4717703_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009964 261.0
HKD1_k127_4717703_4 Acyltransferase - - - 0.0000000000000000000000000000000001336 148.0
HKD1_k127_4717703_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000007373 140.0
HKD1_k127_4719432_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.635e-239 762.0
HKD1_k127_4719432_1 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833,K03851,K12256,K15372 - 2.6.1.113,2.6.1.55,2.6.1.62,2.6.1.77 0.0000000000000000000000000000000000000000000000000000004911 203.0
HKD1_k127_4719432_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000006356 182.0
HKD1_k127_4719432_3 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000005658 122.0
HKD1_k127_4720904_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 7.845e-242 754.0
HKD1_k127_4720904_1 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007717 545.0
HKD1_k127_472910_0 COG1055 Na H antiporter NhaD and related arsenite - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 587.0
HKD1_k127_472910_1 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 390.0
HKD1_k127_472910_2 - - - - 0.0000000000000000000000000000000000001191 152.0
HKD1_k127_472910_3 META domain - - - 0.00000002718 67.0
HKD1_k127_4781576_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 544.0
HKD1_k127_4781576_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 407.0
HKD1_k127_4781576_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 394.0
HKD1_k127_4781576_3 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 323.0
HKD1_k127_4781576_4 Carbon-nitrogen hydrolase K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002829 280.0
HKD1_k127_4781576_5 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003083 262.0
HKD1_k127_4782691_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 7.613e-215 696.0
HKD1_k127_4782691_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 611.0
HKD1_k127_4782691_10 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000507 260.0
HKD1_k127_4782691_11 Cytochrome C biogenesis protein K06196,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000007123 206.0
HKD1_k127_4782691_12 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000009448 201.0
HKD1_k127_4782691_13 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0000000000000000000000000000000000000000000000000636 203.0
HKD1_k127_4782691_14 dUTPase K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000003786 177.0
HKD1_k127_4782691_15 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000001622 191.0
HKD1_k127_4782691_16 MaoC like domain - - - 0.00000000000000000000000000000000000000000004495 164.0
HKD1_k127_4782691_17 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000001205 160.0
HKD1_k127_4782691_18 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000005596 153.0
HKD1_k127_4782691_19 Diguanylate cyclase - - - 0.00000000000000000000000000000000000001469 164.0
HKD1_k127_4782691_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009462 544.0
HKD1_k127_4782691_20 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859,K07566 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24,2.7.7.87 0.0000000000000000000000000000000000007287 161.0
HKD1_k127_4782691_21 dehydratase - - - 0.000000000000000000000000000007225 137.0
HKD1_k127_4782691_22 bacterial (prokaryotic) histone like domain K05788 - - 0.0000000000000000000000000015 115.0
HKD1_k127_4782691_23 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.00000000000000000000005749 113.0
HKD1_k127_4782691_24 helix_turn_helix, cAMP Regulatory protein K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.0000000000000000000001325 107.0
HKD1_k127_4782691_25 Thioredoxin-like - - - 0.000000000000007254 88.0
HKD1_k127_4782691_3 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 537.0
HKD1_k127_4782691_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006542 358.0
HKD1_k127_4782691_5 MutS domain I K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 351.0
HKD1_k127_4782691_6 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005321 338.0
HKD1_k127_4782691_7 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009434 289.0
HKD1_k127_4782691_8 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000003255 257.0
HKD1_k127_4782691_9 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000004894 269.0
HKD1_k127_4794206_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 7.024e-245 790.0
HKD1_k127_4794206_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 3.729e-242 781.0
HKD1_k127_4794206_10 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000000000000912 201.0
HKD1_k127_4794206_11 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000013 158.0
HKD1_k127_4794206_12 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000006935 109.0
HKD1_k127_4794206_13 Domain of Unknown Function (DUF928) - - - 0.000000000000000001127 102.0
HKD1_k127_4794206_14 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.000000000000000005663 93.0
HKD1_k127_4794206_15 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000001091 97.0
HKD1_k127_4794206_16 Protein of unknown function (DUF503) K09764 - - 0.000000000000004253 90.0
HKD1_k127_4794206_17 Protein of unknown function (DUF3349) - - - 0.000000000001819 74.0
HKD1_k127_4794206_18 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000008322 52.0
HKD1_k127_4794206_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 614.0
HKD1_k127_4794206_3 glutamine synthetase K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 556.0
HKD1_k127_4794206_4 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 541.0
HKD1_k127_4794206_5 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007186 495.0
HKD1_k127_4794206_6 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005091 430.0
HKD1_k127_4794206_7 Belongs to the SAICAR synthetase family K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005751 402.0
HKD1_k127_4794206_8 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000004475 266.0
HKD1_k127_4794206_9 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000002455 239.0
HKD1_k127_4798903_0 Enoyl-(Acyl carrier protein) reductase K19548 - 1.1.1.385 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007972 292.0
HKD1_k127_4798903_1 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000000000000002057 218.0
HKD1_k127_4865046_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.107e-221 704.0
HKD1_k127_489595_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 512.0
HKD1_k127_4898585_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0 1947.0
HKD1_k127_4898585_1 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009698 579.0
HKD1_k127_4898585_2 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 393.0
HKD1_k127_4898585_3 Belongs to the Dps family K04047 - - 0.0000000000000000000000000000000000000000407 159.0
HKD1_k127_4956745_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 2.313e-318 1034.0
HKD1_k127_4956745_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 4.548e-213 673.0
HKD1_k127_4956745_2 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 1.729e-209 668.0
HKD1_k127_4956745_3 Bacterial protein of unknown function (DUF937) - - - 0.00000005386 58.0
HKD1_k127_4962392_0 Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate K06447 - 1.2.1.71 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 333.0
HKD1_k127_4962392_1 Oxygen tolerance - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009956 283.0
HKD1_k127_4962392_2 methyltransferase - - - 0.000000000000000000002467 105.0
HKD1_k127_4962392_3 - - - - 0.000000000000000008201 98.0
HKD1_k127_4962392_4 Amidinotransferase - GO:0003674,GO:0003824,GO:0016403,GO:0016787,GO:0016810,GO:0016813 - 0.000000000000001094 92.0
HKD1_k127_4962392_5 von willebrand factor, type A K07114 - - 0.00001963 47.0
HKD1_k127_4962392_6 GDSL-like Lipase/Acylhydrolase K12686 - - 0.0001659 47.0
HKD1_k127_4989943_0 PFAM Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - 2.223e-221 725.0
HKD1_k127_4989943_1 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 402.0
HKD1_k127_4989943_2 transporter antisigma-factor antagonist STAS K17763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004171 328.0
HKD1_k127_4989943_3 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005945 324.0
HKD1_k127_4989943_4 Stage II sporulation protein E - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001545 291.0
HKD1_k127_4989943_5 - - - - 0.0000000000000000000000000000000000000000000000000000001886 205.0
HKD1_k127_4989943_6 Histidine kinase-like ATPases K17752 - 2.7.11.1 0.000000000000000000000000000000000000000000002814 171.0
HKD1_k127_4989943_7 STAS domain K17762 - - 0.00000000000000000000000000000000000000000003162 175.0
HKD1_k127_4989943_8 ATP dependent DNA ligase C terminal region - - - 0.0000000000000000000000000000005583 122.0
HKD1_k127_4989943_9 Histidine kinase A domain protein - - - 0.0000000000000000000000000000006366 130.0
HKD1_k127_5001855_0 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 471.0
HKD1_k127_5001855_2 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000000000000000000000000000000003891 160.0
HKD1_k127_5015569_0 Circularly permuted ATP-grasp type 2 - - - 4.463e-259 822.0
HKD1_k127_5015569_1 transglutaminase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004584 534.0
HKD1_k127_5015569_2 transglutaminase-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 319.0
HKD1_k127_5015569_3 Belongs to the GPI family K01810 - 5.3.1.9 0.0000000000000000000000000000000001599 133.0
HKD1_k127_5019264_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03694,K03695 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0010033,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030312,GO:0030554,GO:0031249,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035966,GO:0036094,GO:0040007,GO:0042221,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - 3.891e-279 872.0
HKD1_k127_5019264_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 414.0
HKD1_k127_5019264_2 PDZ DHR GLGF domain protein K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 380.0
HKD1_k127_5019264_3 Galactokinase galactose-binding signature K00849 - 2.7.1.6 0.000000000000000000000000000000000000000000000000000431 198.0
HKD1_k127_5020527_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.072e-219 690.0
HKD1_k127_5020527_1 synthetase K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 562.0
HKD1_k127_5020527_10 Bacterial regulatory proteins, tetR family - - - 0.00000000000001005 82.0
HKD1_k127_5020527_11 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000009004 78.0
HKD1_k127_5020527_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007737 361.0
HKD1_k127_5020527_3 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 308.0
HKD1_k127_5020527_4 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004564 271.0
HKD1_k127_5020527_5 Protein of unknown function (DUF1679) - - - 0.000000000000000000000000000000000000000000000000000000000000001041 240.0
HKD1_k127_5020527_6 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000199 231.0
HKD1_k127_5020527_7 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000000002622 148.0
HKD1_k127_5020527_8 PFAM phospholipase Carboxylesterase K06999 - - 0.000000000000000000000000000004151 138.0
HKD1_k127_5020527_9 Protein of unknown function (DUF1499) - - - 0.0000000000000000000000004782 114.0
HKD1_k127_50243_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1072.0
HKD1_k127_50243_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 5.46e-231 734.0
HKD1_k127_50243_10 Pfam:N_methyl_2 K02650 - - 0.0000000000000001241 92.0
HKD1_k127_50243_11 TPR repeat - - - 0.0000000000000003371 91.0
HKD1_k127_50243_12 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000001217 85.0
HKD1_k127_50243_13 Type IV pilin PilA K02650 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.000000000000002405 84.0
HKD1_k127_50243_14 Tetratricopeptide repeat - - - 0.00000000001873 75.0
HKD1_k127_50243_15 Helix-turn-helix domain - - - 0.00000004398 64.0
HKD1_k127_50243_2 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 523.0
HKD1_k127_50243_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016625,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0047553,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000987 367.0
HKD1_k127_50243_4 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002009 300.0
HKD1_k127_50243_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000002073 268.0
HKD1_k127_50243_6 ABC-type transport system involved in multi-copper enzyme maturation, permease component - - - 0.00000000000000000000000000000000000000005035 172.0
HKD1_k127_50243_7 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000001244 132.0
HKD1_k127_50243_8 Sigma-70 region 2 K03088 - - 0.000000000000000001628 93.0
HKD1_k127_50243_9 PFAM Exonuclease RNase T and DNA polymerase III K02342 - 2.7.7.7 0.00000000000000000168 94.0
HKD1_k127_5041295_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821,K07250 - 2.6.1.11,2.6.1.17,2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008082 343.0
HKD1_k127_5041295_1 N-succinyltransferase beta subunit K00673 - 2.3.1.109 0.00000000000000000000000000000000000000000000000000000000000005554 241.0
HKD1_k127_5041295_2 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000002986 151.0
HKD1_k127_5041295_3 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000003887 142.0
HKD1_k127_5041295_4 - - - - 0.0000006275 54.0
HKD1_k127_5050946_0 Enoyl-CoA hydratase/isomerase K08299 - 4.2.1.149 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 372.0
HKD1_k127_5050946_1 Amidohydrolase - - - 0.0000000000000000000000000000000000000000008936 177.0
HKD1_k127_5050946_2 Phytanoyl-CoA dioxygenase - - - 0.00000000000000000000000000000000000000001057 156.0
HKD1_k127_5050946_3 cog0421, spermidine synthase - - - 0.000000000000000000002753 95.0
HKD1_k127_5059896_0 PFAM amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000005287 233.0
HKD1_k127_5059896_1 Bacterial regulatory proteins, tetR family K09017 - - 0.00000000000000000000000001677 117.0
HKD1_k127_5059896_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000006669 115.0
HKD1_k127_5059896_3 Iron-containing redox enzyme K06137 - 1.3.3.11 0.00000000000000000000754 101.0
HKD1_k127_5059896_4 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000004303 92.0
HKD1_k127_5059896_5 acyl-CoA dehydrogenase - - - 0.0000000000000004539 78.0
HKD1_k127_5063547_0 3-beta hydroxysteroid dehydrogenase/isomerase family K10011,K12449 - 1.1.1.305,2.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 448.0
HKD1_k127_5063547_1 PFAM AMP-dependent synthetase and ligase K18661 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 314.0
HKD1_k127_5063547_2 Belongs to the MenA family. Type 1 subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 328.0
HKD1_k127_5063547_3 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000005773 229.0
HKD1_k127_5063547_4 glycosyl transferase, family 39 - - - 0.000000000000000000000000000000003651 147.0
HKD1_k127_5069605_0 Penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 603.0
HKD1_k127_5069605_1 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006901 295.0
HKD1_k127_5069605_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000221 174.0
HKD1_k127_5069605_3 - K07018 - - 0.00002496 49.0
HKD1_k127_5069605_4 - - - - 0.0004153 49.0
HKD1_k127_5072286_0 PFAM Cytochrome C assembly protein K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005636 509.0
HKD1_k127_5072286_1 PFAM Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 386.0
HKD1_k127_5072286_2 ABC transporter K02193 - 3.6.3.41 0.0000000000000000000000000000000000004588 162.0
HKD1_k127_5072286_3 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.000000000000000000000000000000000001648 158.0
HKD1_k127_5072286_4 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000002739 98.0
HKD1_k127_5072286_5 NUDIX domain - - - 0.0000000000002632 78.0
HKD1_k127_5072286_6 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000001272 72.0
HKD1_k127_5072286_7 Cytochrome c - - - 0.0003656 55.0
HKD1_k127_5104110_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 1.085e-317 999.0
HKD1_k127_5104110_1 MgsA AAA+ ATPase C terminal K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003899 426.0
HKD1_k127_5104110_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 387.0
HKD1_k127_5104110_3 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 325.0
HKD1_k127_5104110_4 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003147 267.0
HKD1_k127_5104110_5 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000007976 266.0
HKD1_k127_5104110_6 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000000000003339 204.0
HKD1_k127_5104110_7 2-hydroxychromene-2-carboxylate isomerase K14584 - 5.99.1.4 0.00000000000000000000000000000000003547 137.0
HKD1_k127_5104110_8 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000001273 115.0
HKD1_k127_5104110_9 Inner membrane component of T3SS, cytoplasmic domain - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006110,GO:0006140,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010563,GO:0010675,GO:0010677,GO:0016020,GO:0016310,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0030312,GO:0030808,GO:0030809,GO:0030811,GO:0030812,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031330,GO:0036211,GO:0042325,GO:0042326,GO:0042802,GO:0043170,GO:0043412,GO:0043457,GO:0043467,GO:0043470,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045820,GO:0045912,GO:0045934,GO:0045936,GO:0045980,GO:0046777,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051174,GO:0051193,GO:0051195,GO:0051196,GO:0051198,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1900371,GO:1900372,GO:1900542,GO:1900543,GO:1901564,GO:1903578,GO:1903579,GO:2001169,GO:2001170 - 0.00000000000007176 77.0
HKD1_k127_5115320_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000002895 279.0
HKD1_k127_5115320_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000006043 144.0
HKD1_k127_5115320_2 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.000000000001193 78.0
HKD1_k127_511744_0 Belongs to the glycosyl hydrolase 31 family K01187 - 3.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 580.0
HKD1_k127_511744_1 PFAM glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 344.0
HKD1_k127_511744_10 Peptidase S15 K06978 - - 0.00000000000000000000000000000000000000000000000000004045 212.0
HKD1_k127_511744_11 MAPEG family - - - 0.0000000000000000000000000000000000000000000002332 178.0
HKD1_k127_511744_12 NUDIX domain - - - 0.0000000000000000000000000000000000000001369 162.0
HKD1_k127_511744_13 - - - - 0.0000000000000000000000000001946 128.0
HKD1_k127_511744_14 - - - - 0.000000011 68.0
HKD1_k127_511744_15 - - - - 0.0000006233 61.0
HKD1_k127_511744_2 Threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006244 359.0
HKD1_k127_511744_3 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 315.0
HKD1_k127_511744_4 Glutathione S-transferase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008574 302.0
HKD1_k127_511744_5 Protein of unknown function (DUF815) K06923 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007533 276.0
HKD1_k127_511744_6 CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008989 290.0
HKD1_k127_511744_7 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003536 261.0
HKD1_k127_511744_8 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000105 218.0
HKD1_k127_511744_9 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000006109 196.0
HKD1_k127_5134461_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007297 576.0
HKD1_k127_5134461_1 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.000000000000000000000000000000000000000000000000000002833 209.0
HKD1_k127_5134461_2 phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000132 176.0
HKD1_k127_5134461_3 CHAT domain - - - 0.000000000000003202 77.0
HKD1_k127_5149598_0 Malic enzyme, NAD binding domain K00027,K00029,K00625,K04020,K13788 GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.38,1.1.1.40,2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 567.0
HKD1_k127_5149598_1 Carboxyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 550.0
HKD1_k127_5149598_2 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 546.0
HKD1_k127_5149598_3 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 471.0
HKD1_k127_5149598_4 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004251 473.0
HKD1_k127_5149598_5 regulatory protein IclR - - - 0.000000000000000000000000000000000000000000000000000006826 201.0
HKD1_k127_5149598_6 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000002403 178.0
HKD1_k127_5149598_7 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000008066 128.0
HKD1_k127_5152107_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 483.0
HKD1_k127_5152107_1 2-nitropropane dioxygenase K02371 - 1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006777 424.0
HKD1_k127_5152107_2 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 313.0
HKD1_k127_5152107_3 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.000000000000000000000000000000007197 141.0
HKD1_k127_5157850_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 496.0
HKD1_k127_5157850_1 Radical_SAM C-terminal domain K07739 - 2.3.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 452.0
HKD1_k127_5157850_10 Domain of unknown function (DUF4328) - - - 0.0000000000000000292 95.0
HKD1_k127_5157850_11 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000001619 71.0
HKD1_k127_5157850_12 Domain of unknown function (DUF4142) K08995 - - 0.000000003902 68.0
HKD1_k127_5157850_2 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 367.0
HKD1_k127_5157850_3 glycosyl transferase family 8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002329 238.0
HKD1_k127_5157850_4 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000285 235.0
HKD1_k127_5157850_5 Thioesterase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000005605 216.0
HKD1_k127_5157850_6 Serine/Threonine protein kinases, catalytic domain K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.0000000000000000000000000000000000000000000000000003661 211.0
HKD1_k127_5157850_7 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000007111 206.0
HKD1_k127_5157850_8 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000003364 185.0
HKD1_k127_5157850_9 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000000948 135.0
HKD1_k127_5160091_0 Protein of unknown function (DUF1254) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 511.0
HKD1_k127_5160091_1 Leucine carboxyl methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000004661 266.0
HKD1_k127_5160091_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K00320 - 1.5.98.2 0.00000000000000000000000000000000000000000000000000000001521 223.0
HKD1_k127_5160091_3 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000005082 210.0
HKD1_k127_5160091_4 Chalcone isomerase-like - - - 0.0000000000000000000000000000004354 139.0
HKD1_k127_5160091_5 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000001676 102.0
HKD1_k127_5178838_0 DNA helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 524.0
HKD1_k127_5178838_1 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 393.0
HKD1_k127_5178838_10 protein tyrosine phosphatase activity K01104 - 3.1.3.48 0.0000000000000000000000000000005046 142.0
HKD1_k127_5178838_11 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.0000000000000000000000000000007541 129.0
HKD1_k127_5178838_12 Protein of unknown function (DUF4056) - - - 0.0000000000000000000000000004138 122.0
HKD1_k127_5178838_2 NAD dependent epimerase dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 361.0
HKD1_k127_5178838_3 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 310.0
HKD1_k127_5178838_4 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001316 265.0
HKD1_k127_5178838_5 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000034 220.0
HKD1_k127_5178838_6 - - - - 0.0000000000000000000000000000000000000000000182 167.0
HKD1_k127_5178838_7 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000004397 166.0
HKD1_k127_5178838_8 Peptidase, M16 - - - 0.00000000000000000000000000000000000000000005592 186.0
HKD1_k127_5178838_9 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000000000000001678 130.0
HKD1_k127_5185738_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 465.0
HKD1_k127_5185738_1 - - - - 0.000000000000000000000000000006713 120.0
HKD1_k127_5207736_0 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001187 277.0
HKD1_k127_5207736_1 serine O-acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000002588 257.0
HKD1_k127_5207736_2 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 GO:0003674,GO:0003824,GO:0004416,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000001134 235.0
HKD1_k127_5207736_3 PD-(D/E)XK nuclease superfamily K03657,K07465 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000014 202.0
HKD1_k127_5207736_4 F420H(2)-dependent quinone reductase - - - 0.00000000000000000000000000000000000000000000000003987 182.0
HKD1_k127_5207736_5 PFAM Integrase catalytic - - - 0.000000000000000000000000000004044 125.0
HKD1_k127_5207736_6 Thioesterase-like superfamily K07107 - - 0.0000000000001614 84.0
HKD1_k127_5209941_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - - 5.143e-213 723.0
HKD1_k127_5209941_1 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 432.0
HKD1_k127_5209941_2 PFAM acyl-CoA dehydrogenase domain protein K00255,K11731 - 1.3.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008955 385.0
HKD1_k127_5209941_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000001228 192.0
HKD1_k127_5209941_4 carboxylase K11263 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 6.3.4.14,6.4.1.2,6.4.1.3 0.000000000000000000000000000000000000009071 158.0
HKD1_k127_5209941_5 Protoglobin K06595 - - 0.0000000000000000000000007071 119.0
HKD1_k127_5209941_6 IMP dehydrogenase activity K04767,K07182 - - 0.000000000003381 73.0
HKD1_k127_5209941_7 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.0000003824 52.0
HKD1_k127_5215031_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002099 285.0
HKD1_k127_5215031_1 Glycosyl transferase, family 2 K00721,K01912,K08301 - 2.4.1.83,6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000001046 271.0
HKD1_k127_5215031_10 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000001329 71.0
HKD1_k127_5215031_11 Lysylphosphatidylglycerol synthase TM region - - - 0.000002389 61.0
HKD1_k127_5215031_12 Acyltransferase family - - - 0.0000265 57.0
HKD1_k127_5215031_2 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000001331 268.0
HKD1_k127_5215031_3 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000002867 254.0
HKD1_k127_5215031_4 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000543 156.0
HKD1_k127_5215031_5 - - - - 0.000000000000000000000000002813 117.0
HKD1_k127_5215031_6 Methyltransferase domain - - - 0.000000000000000000000000003442 129.0
HKD1_k127_5215031_7 Methionine biosynthesis protein MetW - - - 0.00000000000000000000005862 115.0
HKD1_k127_5215031_9 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.000000000000000002214 99.0
HKD1_k127_5241748_0 UvrD/REP helicase N-terminal domain K03656,K03657 GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 625.0
HKD1_k127_5241748_1 Nuclear transport factor 2 (NTF2) domain K01822 - 5.3.3.1 0.000000000001702 73.0
HKD1_k127_5241748_2 SnoaL-like domain - - - 0.0004016 49.0
HKD1_k127_5255728_0 Putative amidoligase enzyme (DUF2126) - - - 3.885e-319 995.0
HKD1_k127_5265924_0 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000002107 273.0
HKD1_k127_5265924_1 DNA uptake protein and related DNA-binding proteins K02237 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000001164 89.0
HKD1_k127_5299668_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.078e-230 734.0
HKD1_k127_5299668_1 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000005739 180.0
HKD1_k127_5306152_0 metal-dependent hydrolase with the TIM-barrel fold - - - 9.277e-228 721.0
HKD1_k127_5306152_1 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009587 569.0
HKD1_k127_5306152_10 oxidoreductase activity, acting on CH-OH group of donors K16260 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045926,GO:0048519,GO:0050789,GO:0065007,GO:0071944 - 0.00000000000000000000002693 108.0
HKD1_k127_5306152_2 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 554.0
HKD1_k127_5306152_3 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 494.0
HKD1_k127_5306152_4 Bacterial regulatory helix-turn-helix protein, lysR family K04761 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 419.0
HKD1_k127_5306152_5 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005814 376.0
HKD1_k127_5306152_6 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 347.0
HKD1_k127_5306152_7 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002819 295.0
HKD1_k127_5306152_8 Pfam Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000002659 236.0
HKD1_k127_5306152_9 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000006911 219.0
HKD1_k127_532403_0 Fumarase C-terminus K01676 GO:0003674,GO:0003824,GO:0004333,GO:0005488,GO:0005515,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016862,GO:0016999,GO:0017144,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0048037,GO:0050163,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007929 472.0
HKD1_k127_532403_1 GDSL-like Lipase/Acylhydrolase family - - - 0.0000001108 61.0
HKD1_k127_5338046_0 response regulator K10943 - - 0.00000000000000000000000000000000000000000000000000000005461 223.0
HKD1_k127_5338046_1 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000005105 200.0
HKD1_k127_5338046_2 Tetratricopeptide repeat - - - 0.00006445 51.0
HKD1_k127_5339094_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 9.471e-317 982.0
HKD1_k127_5339094_1 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 1.296e-195 646.0
HKD1_k127_5339094_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000008618 246.0
HKD1_k127_5339094_3 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000000001351 226.0
HKD1_k127_5407388_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 372.0
HKD1_k127_5407388_1 acetyltransferase component of pyruvate dehydrogenase complex K00627,K00658 - 2.3.1.12,2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000003873 254.0
HKD1_k127_5407388_2 CBS domain - - - 0.00000000000000000000002836 107.0
HKD1_k127_5407388_3 Phosphopantetheine attachment site - - - 0.0000000000000000001815 98.0
HKD1_k127_5415530_0 FAD binding domain K16051 - 1.3.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008968 433.0
HKD1_k127_5415530_1 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001738 263.0
HKD1_k127_5415530_2 belongs to the aldehyde dehydrogenase family K22445 - 1.2.99.10 0.0000000000000000000000000000000000000000000000001731 178.0
HKD1_k127_5415530_3 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000003041 183.0
HKD1_k127_5415530_4 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00058,K11216 - 1.1.1.399,1.1.1.95,2.7.1.189 0.00000000000000000000000000000000000682 144.0
HKD1_k127_5415530_5 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000002284 102.0
HKD1_k127_5415530_6 - - - - 0.00000000000008147 82.0
HKD1_k127_543411_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 1.226e-204 648.0
HKD1_k127_543411_1 Cytochrome C oxidase, mono-heme subunit/FixO K00405 - - 0.000000000000000000000000000000000000000000000000000000000007854 213.0
HKD1_k127_543411_2 AAA domain K07028 - - 0.0000000000000000000000000000000000004834 158.0
HKD1_k127_543411_3 Universal stress protein family - - - 0.00000000000000000000007866 103.0
HKD1_k127_543411_4 AAA domain K07028 GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009987,GO:0030312,GO:0044464,GO:0044764,GO:0046812,GO:0051704,GO:0071944 - 0.0000000001405 67.0
HKD1_k127_5442352_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 2.92e-198 635.0
HKD1_k127_5442352_1 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 604.0
HKD1_k127_5442352_10 AMP-binding enzyme C-terminal domain K01895,K08295 - 6.2.1.1,6.2.1.32 0.000000002387 62.0
HKD1_k127_5442352_2 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 580.0
HKD1_k127_5442352_3 Domain of unknown function (DUF4915) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 547.0
HKD1_k127_5442352_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 482.0
HKD1_k127_5442352_5 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 407.0
HKD1_k127_5442352_6 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 392.0
HKD1_k127_5442352_7 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003005 267.0
HKD1_k127_5442352_8 Domain of unknown function (DUF4915) - - - 0.00000000000000000000000000000000000000000000000000000000000005048 220.0
HKD1_k127_5442352_9 Phosphoglycerate mutase - - - 0.0000000000000000000000000000000000000016 156.0
HKD1_k127_5458762_0 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 6.373e-269 851.0
HKD1_k127_5458762_1 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 535.0
HKD1_k127_5458762_10 - - - - 0.000000000000000000000000001198 118.0
HKD1_k127_5458762_11 Tetratricopeptide repeat - - - 0.00000000000000000003827 100.0
HKD1_k127_5458762_12 CRS1_YhbY K07574 - - 0.000000000000002132 85.0
HKD1_k127_5458762_13 SNARE-like domain protein - - - 0.000000009395 66.0
HKD1_k127_5458762_2 carnitine dehydratase K01796 - 5.1.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 497.0
HKD1_k127_5458762_3 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 442.0
HKD1_k127_5458762_4 Carboxylesterase family K03929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009212 362.0
HKD1_k127_5458762_5 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005486 301.0
HKD1_k127_5458762_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002319 265.0
HKD1_k127_5458762_7 ACT domain - - - 0.0000000000000000000000000000000000000000000001888 175.0
HKD1_k127_5458762_8 SMART Transcription regulator LuxR, C-terminal - - - 0.00000000000000000000000000000000000000006114 166.0
HKD1_k127_5458762_9 RES - - - 0.000000000000000000000000000004573 130.0
HKD1_k127_546595_0 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 514.0
HKD1_k127_546595_1 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006963 297.0
HKD1_k127_546595_2 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004671 271.0
HKD1_k127_546595_3 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000007731 228.0
HKD1_k127_546595_4 AIR carboxylase K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000005427 186.0
HKD1_k127_546595_5 COG NOG14600 non supervised orthologous group - - - 0.0000000000000000000000000000000000009384 139.0
HKD1_k127_546595_6 4 iron, 4 sulfur cluster binding K05524 GO:0001666,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0009628,GO:0036293,GO:0043207,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0070482,GO:0075136 - 0.00000000000000000000000000000000007753 138.0
HKD1_k127_546595_7 Belongs to the bacterial ribosomal protein bL33 family K02913 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000002561 93.0
HKD1_k127_546595_8 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000009142 90.0
HKD1_k127_546595_9 TIGRFAM Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.0000000000002491 70.0
HKD1_k127_5479074_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 454.0
HKD1_k127_5479074_1 Histidine-specific methyltransferase, SAM-dependent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 321.0
HKD1_k127_5479074_2 acetyl-coa acetyltransferase K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000162 201.0
HKD1_k127_5479074_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000007847 168.0
HKD1_k127_5527939_0 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 349.0
HKD1_k127_5527939_1 Protein of unknown function (DUF3570) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002013 277.0
HKD1_k127_5527939_2 PFAM type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000002498 208.0
HKD1_k127_5527939_3 Thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000002428 147.0
HKD1_k127_5527939_4 - - - - 0.000000000000004898 81.0
HKD1_k127_5527939_5 Domain of unknown function (DUF4266) - - - 0.0000000003943 71.0
HKD1_k127_5527939_6 Outer membrane protein beta-barrel domain - - - 0.0003379 51.0
HKD1_k127_5557105_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008729 573.0
HKD1_k127_5557105_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 407.0
HKD1_k127_5557105_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 403.0
HKD1_k127_5557105_3 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 346.0
HKD1_k127_5557105_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008095 323.0
HKD1_k127_5557105_5 Transcriptional regulator - - - 0.000000000000000000000000000000000000001138 153.0
HKD1_k127_5557105_6 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.0000000000000000000000000000000002058 154.0
HKD1_k127_5557105_8 Selenide, water dikinase K01008 - 2.7.9.3 0.00006045 46.0
HKD1_k127_5562726_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000056 628.0
HKD1_k127_5562726_1 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002597 289.0
HKD1_k127_5562726_2 Histidine kinase K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000007689 160.0
HKD1_k127_5562726_3 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000004088 158.0
HKD1_k127_556983_0 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001381 282.0
HKD1_k127_556983_1 MotA/TolQ/ExbB proton channel family - - - 0.00000000000000000000000000000000000000000000000000000000000000000008939 245.0
HKD1_k127_556983_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000002532 168.0
HKD1_k127_556983_3 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000000000000000000000232 170.0
HKD1_k127_556983_4 Biopolymer transport protein ExbD/TolR - - - 0.0000000000000000000000000000000000000118 162.0
HKD1_k127_556983_5 Tetratricopeptide repeat - - - 0.00000000000000000002468 94.0
HKD1_k127_556983_6 - - - - 0.0000000000001179 81.0
HKD1_k127_5588500_0 ABC-type multidrug transport system ATPase and permease K06147,K06148 - - 4.82e-275 857.0
HKD1_k127_5588500_1 ABC-type multidrug transport system ATPase and permease K06147 - - 2.258e-209 660.0
HKD1_k127_5588500_2 Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003012 544.0
HKD1_k127_5588500_3 Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003014 270.0
HKD1_k127_5588500_4 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000155 250.0
HKD1_k127_5588500_5 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000004964 190.0
HKD1_k127_5596971_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 453.0
HKD1_k127_5596971_1 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 414.0
HKD1_k127_5596971_2 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004707 384.0
HKD1_k127_5596971_3 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 357.0
HKD1_k127_5596971_4 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007779 334.0
HKD1_k127_5596971_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009856 356.0
HKD1_k127_5596971_6 protoporphyrinogen oxidase activity K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000007605 170.0
HKD1_k127_5608110_0 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 2.667e-203 647.0
HKD1_k127_5608110_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 551.0
HKD1_k127_5608110_2 Chalcone and stilbene synthases, C-terminal domain K16167,K19580 - 2.3.1.233 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006994 409.0
HKD1_k127_5608110_3 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000362 387.0
HKD1_k127_5608110_4 Cytochrome P450 K17474 - 1.14.15.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 342.0
HKD1_k127_5608110_5 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001482 278.0
HKD1_k127_5608110_6 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001732 265.0
HKD1_k127_5608110_7 Alpha beta hydrolase K14731 - 3.1.1.83 0.000000000000000000000000000000000000000000000000000000000000000000002003 246.0
HKD1_k127_5608110_8 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K16168 - - 0.000000000000000000000000000000000000000000000000001354 199.0
HKD1_k127_5608110_9 Belongs to the cytochrome P450 family - - - 0.000000000000000000000000000000000005736 152.0
HKD1_k127_5652688_0 COG0625 Glutathione S-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 391.0
HKD1_k127_5652688_1 Sulfotransferase domain K01014 - 2.8.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000789 250.0
HKD1_k127_5652688_2 - - - - 0.0000000000000000000000000000000000000000000000000000000002259 225.0
HKD1_k127_5652688_3 Protein of unknown function (DUF2855) - - - 0.00000000000000000000000000004441 119.0
HKD1_k127_5688116_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 574.0
HKD1_k127_5688116_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 336.0
HKD1_k127_5688116_10 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000001441 125.0
HKD1_k127_5688116_11 peptidyl-tyrosine sulfation - - - 0.000000000000001473 91.0
HKD1_k127_5688116_12 Roadblock/LC7 domain - - - 0.00000000000002248 85.0
HKD1_k127_5688116_13 Putative zinc-finger - - - 0.0005355 52.0
HKD1_k127_5688116_2 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008654 314.0
HKD1_k127_5688116_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001948 243.0
HKD1_k127_5688116_4 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000006112 207.0
HKD1_k127_5688116_5 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000000000000000004942 218.0
HKD1_k127_5688116_6 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000003254 186.0
HKD1_k127_5688116_7 COG3420 Nitrous oxidase accessory protein - - - 0.0000000000000000000000000000000000003416 154.0
HKD1_k127_5688116_8 Pfam:Arch_ATPase - - - 0.00000000000000000000000000000000002459 148.0
HKD1_k127_5688116_9 belongs to the sigma-70 factor family, ECF subfamily K03088 GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000004277 128.0
HKD1_k127_5688155_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007912 484.0
HKD1_k127_5688155_1 4Fe-4S dicluster domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000001794 228.0
HKD1_k127_5688155_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000002328 164.0
HKD1_k127_5688155_3 PFAM FAD linked oxidase domain protein K00104,K11472 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.3.15 0.000000000000000000000000000000000001811 160.0
HKD1_k127_5688155_4 C4-type zinc ribbon domain K07164 - - 0.0000000001596 70.0
HKD1_k127_5688155_5 Tetratricopeptide repeat - - - 0.0000001016 63.0
HKD1_k127_5688155_6 cellulase activity - - - 0.00001292 57.0
HKD1_k127_5715869_0 lipid-transfer protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 582.0
HKD1_k127_5715869_1 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 488.0
HKD1_k127_5715869_2 short-chain dehydrogenase K07124 - - 0.000000000000000000000000000000000000000000000000000000000001097 219.0
HKD1_k127_5715869_3 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.000000000000000000000000000000000000006922 168.0
HKD1_k127_5719382_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.933e-198 634.0
HKD1_k127_5719382_1 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006147 541.0
HKD1_k127_5719382_10 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002673 305.0
HKD1_k127_5719382_11 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000423 296.0
HKD1_k127_5719382_12 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000001701 270.0
HKD1_k127_5719382_13 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000007347 256.0
HKD1_k127_5719382_14 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000001645 235.0
HKD1_k127_5719382_15 NUBPL iron-transfer P-loop NTPase K04562 - - 0.000000000000000000000000000000000000000000000000000000000000000008407 245.0
HKD1_k127_5719382_16 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000001348 234.0
HKD1_k127_5719382_17 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.0000000000000000000000000000000000000000000000000000000002624 209.0
HKD1_k127_5719382_18 Cytidylyltransferase-like K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.00000000000000000000000000000000000259 158.0
HKD1_k127_5719382_19 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000001884 123.0
HKD1_k127_5719382_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 472.0
HKD1_k127_5719382_20 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000002923 137.0
HKD1_k127_5719382_21 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000015 115.0
HKD1_k127_5719382_22 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000001867 115.0
HKD1_k127_5719382_23 YMGG-like Gly-zipper - - - 0.000000000000000000000001142 119.0
HKD1_k127_5719382_24 Helix-turn-helix domain - - - 0.0000000000000000000003523 112.0
HKD1_k127_5719382_25 Competence protein - - - 0.000000000000000000002251 101.0
HKD1_k127_5719382_26 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000004486 91.0
HKD1_k127_5719382_27 - - - - 0.00000000000001721 79.0
HKD1_k127_5719382_28 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.000000007029 68.0
HKD1_k127_5719382_29 - - - - 0.000000007207 69.0
HKD1_k127_5719382_3 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 456.0
HKD1_k127_5719382_4 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008072 400.0
HKD1_k127_5719382_5 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004231 395.0
HKD1_k127_5719382_6 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 367.0
HKD1_k127_5719382_7 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005426 350.0
HKD1_k127_5719382_8 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 340.0
HKD1_k127_5719382_9 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 338.0
HKD1_k127_5729825_0 ATP dependent DNA ligase C terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006533 514.0
HKD1_k127_5729825_1 dna ligase - - - 0.00000000000000002725 81.0
HKD1_k127_5729825_2 - - - - 0.00000000000000009813 85.0
HKD1_k127_5729825_3 - - - - 0.00000000086 66.0
HKD1_k127_5729825_4 negative regulation of transcription, DNA-templated K02171 - - 0.0000002722 58.0
HKD1_k127_5733760_0 Putative serine dehydratase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 453.0
HKD1_k127_5733760_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008094 406.0
HKD1_k127_5733760_2 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 350.0
HKD1_k127_5733760_3 PFAM type II secretion system protein E K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009183 336.0
HKD1_k127_5733760_5 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.0000005811 60.0
HKD1_k127_5748698_0 AMP-binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 447.0
HKD1_k127_5748698_1 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000298 364.0
HKD1_k127_5748698_10 Tetratricopeptide repeat - - - 0.00000000000005355 86.0
HKD1_k127_5748698_11 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000007158 74.0
HKD1_k127_5748698_12 Belongs to the phosphoglycerate mutase family K02226,K15640,K22305 - 3.1.3.3,3.1.3.73 0.000000001211 60.0
HKD1_k127_5748698_14 Periplasmic protein - - - 0.000001386 58.0
HKD1_k127_5748698_2 PFAM Major Facilitator Superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000303 267.0
HKD1_k127_5748698_3 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000009884 269.0
HKD1_k127_5748698_4 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000002252 191.0
HKD1_k127_5748698_5 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.0000000000000000000000000000000000000000000007813 176.0
HKD1_k127_5748698_6 glycosyl hydrolase 38 domain protein K01191 - 3.2.1.24 0.0000000000000000000000000000000000000000001482 178.0
HKD1_k127_5748698_7 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.00000000000000000000000000000000000000008518 162.0
HKD1_k127_5748698_8 GGDEF domain K03413 - - 0.0000000000000000000000000000000000000002144 165.0
HKD1_k127_5748698_9 Belongs to the UPF0109 family K06960 - - 0.000000000000000000001757 96.0
HKD1_k127_575899_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004662 564.0
HKD1_k127_575899_1 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007178 493.0
HKD1_k127_575899_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 465.0
HKD1_k127_575899_3 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009027 357.0
HKD1_k127_575899_4 PFAM ABC transporter related K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001368 295.0
HKD1_k127_575899_5 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000000000000000000000000000769 237.0
HKD1_k127_575899_6 PFAM DSBA oxidoreductase - - - 0.000000000000000000000000000000000000000000001998 190.0
HKD1_k127_575899_7 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.000000000000000000000000000003775 126.0
HKD1_k127_575899_8 lipopolysaccharide binding K09774 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0010876,GO:0015920,GO:0016020,GO:0017089,GO:0019867,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044462,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264 - 0.000002398 60.0
HKD1_k127_5762498_0 PFAM Radical SAM K11779 - 2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006649 400.0
HKD1_k127_5762498_1 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005842 346.0
HKD1_k127_5762498_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 301.0
HKD1_k127_5762498_3 - - - - 0.00000000000000000000000000000002858 131.0
HKD1_k127_5762498_4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000006756 78.0
HKD1_k127_5762498_5 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000002023 83.0
HKD1_k127_5803691_0 Peptidase dimerisation domain K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 445.0
HKD1_k127_5803691_1 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003667 300.0
HKD1_k127_5808011_0 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006411 435.0
HKD1_k127_5808011_1 Belongs to the peptidase M48B family K03799 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044425,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 323.0
HKD1_k127_5808011_2 Aldo Keto reductase K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000005908 253.0
HKD1_k127_5808011_3 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.00000000000000000000000000000000000000000000000000004409 196.0
HKD1_k127_5808011_4 P-aminobenzoate N-oxygenase AurF - - - 0.0000000000000000000000000000000000000000000000000005205 205.0
HKD1_k127_5808011_5 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000913 145.0
HKD1_k127_5808011_6 Belongs to the peptidase M48B family K03799 - - 0.00000003307 55.0
HKD1_k127_5808011_7 - - - - 0.00005092 53.0
HKD1_k127_5827403_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 591.0
HKD1_k127_5827403_1 AlkA N-terminal domain K13529,K13530 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 533.0
HKD1_k127_5827403_10 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000000000000267 88.0
HKD1_k127_5827403_11 Outer membrane lipoprotein-sorting protein - - - 0.000000000004912 77.0
HKD1_k127_5827403_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006945 308.0
HKD1_k127_5827403_3 PFAM phospholipase Carboxylesterase K06999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001346 285.0
HKD1_k127_5827403_4 Type II secretory pathway, component ExeA K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000002118 233.0
HKD1_k127_5827403_5 dCMP deaminase activity K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000004153 200.0
HKD1_k127_5827403_6 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.0000000000000000000000000000000000000000000000002424 201.0
HKD1_k127_5827403_7 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000003546 171.0
HKD1_k127_5827403_8 Belongs to the phosphoglycerate mutase family K02226,K15634,K22305 - 3.1.3.3,3.1.3.73,5.4.2.12 0.000000000000000000000000000000000000001227 155.0
HKD1_k127_5827403_9 AAA domain - - - 0.00000000000000000000000001043 122.0
HKD1_k127_5854_0 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005359 303.0
HKD1_k127_5854_1 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000001296 119.0
HKD1_k127_5854_2 Serine aminopeptidase, S33 K01055 - 3.1.1.24 0.00002261 58.0
HKD1_k127_5861230_0 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 394.0
HKD1_k127_5861230_1 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000152 282.0
HKD1_k127_5892335_0 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009172 505.0
HKD1_k127_5892335_1 Predicted membrane protein (DUF2339) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001706 304.0
HKD1_k127_5892335_2 Protein of unknown function (DUF3999) - - - 0.000001733 63.0
HKD1_k127_5915862_0 ABC-type multidrug transport system ATPase and permease K06147,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 391.0
HKD1_k127_5917219_0 Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007554 600.0
HKD1_k127_5917219_1 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001947 305.0
HKD1_k127_5917219_2 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001836 259.0
HKD1_k127_5917219_3 MOSC domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001462 240.0
HKD1_k127_5917219_4 Aspartyl/Asparaginyl beta-hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000000005579 222.0
HKD1_k127_5917219_5 Tail Collar - - - 0.0000000000000000000000000000000000000000000000000000000003379 207.0
HKD1_k127_5917219_6 Tail Collar - - - 0.000000000000000000000000000000000000000000000000000000003405 203.0
HKD1_k127_5917219_7 Phage Tail Collar Domain - - - 0.00000000000000000006958 105.0
HKD1_k127_5954871_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003625 548.0
HKD1_k127_5954871_1 Biotin-lipoyl like K15727 - - 0.000000000000000000000000000000000000000000000000000004565 199.0
HKD1_k127_5954871_2 Outer membrane efflux protein K15725 - - 0.0000000000000000000000000000000000000000000001335 186.0
HKD1_k127_5954871_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion K15727 - - 0.00000000000009076 84.0
HKD1_k127_5954871_4 acyl-CoA dehydrogenase - - - 0.000005238 51.0
HKD1_k127_596999_0 Belongs to the glycosyl hydrolase 1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 525.0
HKD1_k127_596999_1 beta-glucosidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008151 503.0
HKD1_k127_596999_2 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000001187 152.0
HKD1_k127_596999_3 Mechanosensitive ion channel K16052 - - 0.0000000000000000000001171 109.0
HKD1_k127_5985469_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005787 444.0
HKD1_k127_5985469_1 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008951 351.0
HKD1_k127_5985469_2 MOSC domain containing protein K07140 - - 0.0000000000000000000000000000000000000000000000000000000002729 212.0
HKD1_k127_5985469_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000007949 207.0
HKD1_k127_5985469_4 Pyridoxal-phosphate dependent enzyme K01738 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.0000000000000000000000000000000000000000000000001316 177.0
HKD1_k127_6001179_0 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005883 352.0
HKD1_k127_6001179_1 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 316.0
HKD1_k127_6001179_2 PFAM cytochrome P450 - - - 0.000000000000000000000000000000002615 135.0
HKD1_k127_600336_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005657 362.0
HKD1_k127_600336_1 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 307.0
HKD1_k127_600336_2 tRNA processing K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002923 286.0
HKD1_k127_600336_3 Sulfatase K01133 - 3.1.6.6 0.0000000000000000000000000000000000000000000007117 188.0
HKD1_k127_600336_4 COG0457 FOG TPR repeat - - - 0.00000000001475 78.0
HKD1_k127_600336_6 COG0457 FOG TPR repeat - - - 0.0000001335 65.0
HKD1_k127_600336_7 TPR repeat-containing protein - - - 0.0000004185 61.0
HKD1_k127_600336_8 repeat protein - - - 0.0000005216 64.0
HKD1_k127_6003573_0 Protein of unknown function (DUF3179) - - - 0.000000000000000000000000000000000000000000000000000000000000000000004237 248.0
HKD1_k127_6003573_1 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000002457 245.0
HKD1_k127_6003573_2 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000002051 201.0
HKD1_k127_6003573_3 PFAM FAD dependent oxidoreductase K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000007469 185.0
HKD1_k127_6003573_4 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000001028 112.0
HKD1_k127_6003573_6 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0001699 51.0
HKD1_k127_6019544_0 AMP-binding enzyme C-terminal domain K00666,K01897 - 6.2.1.3 1.039e-203 649.0
HKD1_k127_6019544_1 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 361.0
HKD1_k127_6019544_2 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000001245 216.0
HKD1_k127_6019544_3 - - - - 0.00000000004642 76.0
HKD1_k127_6029226_0 Molydopterin dinucleotide binding domain - - - 6.882e-284 904.0
HKD1_k127_6029226_1 Protein of unknown function (DUF3604) - - - 3.056e-221 707.0
HKD1_k127_6029226_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 320.0
HKD1_k127_6029226_3 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005377 276.0
HKD1_k127_6029226_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002453 260.0
HKD1_k127_6029226_5 PFAM Ribulose bisphosphate carboxylase large chain K01601 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000001566 206.0
HKD1_k127_6029226_6 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000000000000000001855 177.0
HKD1_k127_6029226_7 Limonene-1,2-epoxide hydrolase catalytic domain K06893 - - 0.00000000000000003914 94.0
HKD1_k127_6037764_0 TIGRFAM polysaccharide deactylase family protein, PEP-CTERM locus subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 301.0
HKD1_k127_6037764_1 TIGRFAM exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005365 275.0
HKD1_k127_6037764_2 TIGRFAM FemAB-related protein, PEP-CTERM - - - 0.0000000000000000000000000000000000000000000000000000000000000009519 232.0
HKD1_k127_6037764_3 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000005438 224.0
HKD1_k127_6037764_4 Lipopolysaccharide biosynthesis protein - - - 0.000000000000000000000000000000004637 148.0
HKD1_k127_6037764_5 Low molecular weight phosphotyrosine protein phosphatase K01104 - 3.1.3.48 0.0000000000000000000004236 103.0
HKD1_k127_6037764_6 Chain length determinant protein K08253 - 2.7.10.2 0.0000000000000000002503 98.0
HKD1_k127_6037764_7 Cyclic nucleotide-monophosphate binding domain K00384 - 1.8.1.9 0.0000000009741 60.0
HKD1_k127_6037764_8 Glycosyl transferase - - - 0.00000002498 66.0
HKD1_k127_6068334_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835,K01840 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 430.0
HKD1_k127_6068334_1 Uncharacterised protein family UPF0052 - - - 0.000000000000000000000000000000000000000000000000000000000000000002724 257.0
HKD1_k127_6068334_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000125 223.0
HKD1_k127_6068334_3 arylsulfatase A - - - 0.000000000000000000000000000000000000000002399 172.0
HKD1_k127_6088308_0 Required for the activity of the bacterial periplasmic transport system of putrescine K11069 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 426.0
HKD1_k127_6088308_1 Aminotransferase class-III K12256 - 2.6.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004171 425.0
HKD1_k127_6088308_2 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 383.0
HKD1_k127_6088308_3 Binding-protein-dependent transport system inner membrane component K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008214 361.0
HKD1_k127_6088308_4 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 323.0
HKD1_k127_6088308_5 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000943 325.0
HKD1_k127_6088308_6 Binding-protein-dependent transport system inner membrane component K11070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000734 311.0
HKD1_k127_6088308_7 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002899 245.0
HKD1_k127_6088308_8 - - - - 0.0000000000000000000000000000000000000000001558 171.0
HKD1_k127_6088308_9 PFAM Glutathione-dependent formaldehyde-activating, GFA - - - 0.000000000002366 72.0
HKD1_k127_6105874_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 413.0
HKD1_k127_6105874_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00000000000000000000000000000000000000000000000000000000006355 234.0
HKD1_k127_6110612_0 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007127 484.0
HKD1_k127_6110612_1 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 385.0
HKD1_k127_6110612_2 DNA photolyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 330.0
HKD1_k127_6110612_3 monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005583 250.0
HKD1_k127_6110612_4 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.000000000000000000000000000000000000000000000000000000000000000000004246 249.0
HKD1_k127_6110612_5 Cytochrome c mono- and diheme variants - - - 0.00000000000000000000000000000000000000000000005248 185.0
HKD1_k127_6110612_6 cobalamin biosynthesis protein CobW K02234 - - 0.00000000000000000000000000000000000000000002738 172.0
HKD1_k127_6110612_7 Rieske 2Fe-2S - - - 0.000000000000000000000000000000000004848 139.0
HKD1_k127_6110612_8 - - - - 0.0000000000000000000000034 120.0
HKD1_k127_6110612_9 ankyrin repeat K06867 - - 0.000000001215 65.0
HKD1_k127_612530_0 glycosyl - - - 0.00000000000000000000007038 114.0
HKD1_k127_612530_1 - - - - 0.0000000000001935 83.0
HKD1_k127_612530_2 Protein tyrosine serine phosphatase - - - 0.00001037 59.0
HKD1_k127_6126472_0 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 7.185e-208 673.0
HKD1_k127_6126472_1 TIGRFAM hopanoid biosynthesis associated RND transporter like protein HpnN K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 558.0
HKD1_k127_6126472_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 363.0
HKD1_k127_6126472_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004666 367.0
HKD1_k127_6126472_4 (Lipo)protein K04754 - - 0.00000000000000000000000000000000000000000000004739 180.0
HKD1_k127_6126472_5 PFAM toluene tolerance family protein K07323 - - 0.0000000000000000000000000000000000001191 151.0
HKD1_k127_612650_0 Tetratricopeptide repeat - - - 4.476e-280 889.0
HKD1_k127_612650_1 Heat shock 70 kDa protein K04043 - - 9.492e-200 638.0
HKD1_k127_612650_10 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000001185 68.0
HKD1_k127_612650_2 Tetratricopeptide repeat - - - 3.753e-197 671.0
HKD1_k127_612650_3 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006789 581.0
HKD1_k127_612650_4 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065,K13252 - 2.1.3.3,2.1.3.6,2.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009642 334.0
HKD1_k127_612650_5 Amino acid kinase family K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 334.0
HKD1_k127_612650_6 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000006469 213.0
HKD1_k127_612650_7 - - - - 0.0000000000000000000000000000000000000000000000007397 183.0
HKD1_k127_612650_8 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.0000000000000000000000002814 107.0
HKD1_k127_612650_9 DnaJ molecular chaperone homology domain - - - 0.0000000000000000002668 102.0
HKD1_k127_6128838_0 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 602.0
HKD1_k127_6128838_1 Flavoprotein involved in K transport K03379 - 1.14.13.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004586 574.0
HKD1_k127_6128838_2 Protein of unknown function (DUF1214) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005578 491.0
HKD1_k127_6128838_3 AMP-binding enzyme C-terminal domain K18661 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000613 451.0
HKD1_k127_6128838_4 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 358.0
HKD1_k127_6128838_5 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000006187 248.0
HKD1_k127_6128838_6 - - - - 0.00000000000000000000006701 106.0
HKD1_k127_6128838_7 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K18661 - - 0.000000000000000000006166 107.0
HKD1_k127_6128838_8 - - - - 0.000003761 60.0
HKD1_k127_6128980_0 ATPase associated with various cellular activities AAA_5 K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000526 370.0
HKD1_k127_6128980_1 VWA domain containing CoxE-like protein K07161 - - 0.0000000000000000000000000000000000000002734 158.0
HKD1_k127_6131045_0 Thioredoxin-like - - - 0.00000000000000000001009 98.0
HKD1_k127_6131045_1 - - - - 0.0000000007024 71.0
HKD1_k127_6136423_0 TIGRFAM phosphoenolpyruvate-protein phosphotransferase K08484 - 2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007303 573.0
HKD1_k127_6136423_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001759 262.0
HKD1_k127_6136423_2 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000003983 175.0
HKD1_k127_6136423_3 integral membrane protein - - - 0.00000000000000000001284 104.0
HKD1_k127_6136423_4 PFAM helix-turn-helix domain protein - - - 0.0000000008883 68.0
HKD1_k127_6136423_5 AsmA-like C-terminal region - - - 0.000000001825 72.0
HKD1_k127_6138478_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 551.0
HKD1_k127_6138478_1 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005543 374.0
HKD1_k127_6138478_2 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000000002052 205.0
HKD1_k127_6138478_3 CHRD domain - - - 0.000000000000000000001051 103.0
HKD1_k127_6138478_4 domain, Protein - - - 0.00000000000000007842 86.0
HKD1_k127_6149407_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.226e-286 903.0
HKD1_k127_6149407_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.9e-202 652.0
HKD1_k127_6149407_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008748 527.0
HKD1_k127_6149407_3 Protein of unknown function (DUF1295) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001089 258.0
HKD1_k127_6149407_4 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000001127 166.0
HKD1_k127_6149407_5 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000004298 152.0
HKD1_k127_6149407_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000001129 67.0
HKD1_k127_6149407_7 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.000003242 53.0
HKD1_k127_6156788_0 Nitrous oxide reductase K00376 - 1.7.2.4 1.345e-255 804.0
HKD1_k127_6156788_1 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008075 387.0
HKD1_k127_6156788_2 Cytochrome c - - - 0.000000000000000000000003315 109.0
HKD1_k127_6156788_3 - - - - 0.00000000000000000000002659 115.0
HKD1_k127_6156788_4 - - - - 0.0000000000000001342 94.0
HKD1_k127_6173809_0 PFAM nucleic acid binding, OB-fold, tRNA - - - 0.00000000000000000006829 100.0
HKD1_k127_6180508_0 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006175 532.0
HKD1_k127_6180508_1 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007954 410.0
HKD1_k127_6180508_2 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000005008 207.0
HKD1_k127_6180508_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775,K18348 - 5.1.1.1,5.1.1.18 0.00000000000000000000000000000000000000000000009902 177.0
HKD1_k127_6180508_4 Belongs to the SUA5 family K07566 GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.87 0.000000000000000000000000009464 124.0
HKD1_k127_6186957_0 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 523.0
HKD1_k127_6186957_1 4,5-dihydroxyphthalate decarboxylase K04102 - 4.1.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 404.0
HKD1_k127_6186957_2 Gentisate 1,2-dioxygenase K00450 - 1.13.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000136 286.0
HKD1_k127_6186957_3 nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003002 262.0
HKD1_k127_6186957_4 - - - - 0.000000000000000000000000000000003078 145.0
HKD1_k127_6186957_5 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000004797 79.0
HKD1_k127_6200100_0 alcohol dehydrogenase K00001,K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 449.0
HKD1_k127_6200100_1 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 353.0
HKD1_k127_6200100_2 ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000001331 219.0
HKD1_k127_6200100_3 PFAM glycosyl transferase family 9 K02843 - - 0.00000000000000000000000000000000000000000000007777 192.0
HKD1_k127_6200100_4 - - - - 0.000000000000000000000000000000000000000002011 164.0
HKD1_k127_6200100_6 enzyme involved in biosynthesis of extracellular polysaccharides - - - 0.0008195 42.0
HKD1_k127_6261431_0 Protein of unknown function (DUF3604) - - - 1.23e-203 677.0
HKD1_k127_6261431_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009213 337.0
HKD1_k127_6261431_2 cytochrome p450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 300.0
HKD1_k127_6261431_3 Cro/C1-type HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000001918 213.0
HKD1_k127_6261431_4 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000003049 156.0
HKD1_k127_6261431_5 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000006295 117.0
HKD1_k127_6261431_6 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000005819 98.0
HKD1_k127_6284994_0 glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000003227 241.0
HKD1_k127_6284994_1 Mechanosensitive ion channel K05802 - - 0.00000000000000000000000000000000000000000000181 170.0
HKD1_k127_6290794_0 ABC transporter K03701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 355.0
HKD1_k127_6290794_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000001272 171.0
HKD1_k127_6290794_2 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.00000000000000001754 94.0
HKD1_k127_6290875_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007124 372.0
HKD1_k127_6290875_1 cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007502 370.0
HKD1_k127_6290875_2 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000001203 198.0
HKD1_k127_6290875_3 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000001909 174.0
HKD1_k127_6290875_4 NnrU protein - - - 0.0000000000000000000003536 105.0
HKD1_k127_6290875_5 PFAM Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.00000000000000002198 87.0
HKD1_k127_6290875_6 Tetratricopeptide TPR_2 repeat protein - - - 0.000001073 62.0
HKD1_k127_6309033_0 PFAM Mammalian cell entry related domain protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000004787 239.0
HKD1_k127_6309033_1 ABC-type transport auxiliary lipoprotein component K18480 - - 0.000000000000000000000000000004735 132.0
HKD1_k127_6309033_2 ABC transporter K02065 - - 0.000000000000000000000000004723 111.0
HKD1_k127_631308_0 aminopeptidase - - - 0.00000000000000000000000000000000000000002173 167.0
HKD1_k127_631308_1 Methylates ribosomal protein L11 K02687 - - 0.00000000000000000000000000005614 128.0
HKD1_k127_631308_2 Sulfotransferase family - - - 0.000000005707 57.0
HKD1_k127_631308_3 GDP-mannose 4,6 dehydratase K15856 - 1.1.1.281 0.0000001347 57.0
HKD1_k127_6358945_0 Voltage gated chloride channel K03281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 581.0
HKD1_k127_6358945_1 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004069 473.0
HKD1_k127_6358945_2 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008433 391.0
HKD1_k127_6358945_3 LssY C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008892 307.0
HKD1_k127_6358945_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004285 296.0
HKD1_k127_6358945_5 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004414 278.0
HKD1_k127_6358945_6 PFAM CheB methylesterase K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000001277 196.0
HKD1_k127_6358945_7 cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000001447 121.0
HKD1_k127_6358945_8 DNA polymerase Ligase (LigD) - - - 0.000000000000000000002327 103.0
HKD1_k127_6370954_0 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007769 314.0
HKD1_k127_6370954_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K15785 - 2.6.1.76 0.000000000000000000000000007948 113.0
HKD1_k127_6370954_2 dehydratase K17865 - 4.2.1.55 0.0000006615 59.0
HKD1_k127_6380725_0 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009138 297.0
HKD1_k127_6380725_1 endonuclease activity K07451 - - 0.000000000000000000000000000000000000004858 168.0
HKD1_k127_6385510_0 Putative modulator of DNA gyrase K03568 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 580.0
HKD1_k127_6385510_1 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009655 422.0
HKD1_k127_6385510_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000001752 225.0
HKD1_k127_6449746_0 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 309.0
HKD1_k127_6449746_1 beta-N-acetylglucosaminidase K01197 - 3.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000005 258.0
HKD1_k127_6449746_2 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001956 256.0
HKD1_k127_6452369_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 4.002e-272 861.0
HKD1_k127_6452369_1 Heat shock 70 kDa protein K04043 - - 1.072e-248 781.0
HKD1_k127_6452369_2 DnaJ central domain K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 447.0
HKD1_k127_6452369_3 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000002036 259.0
HKD1_k127_6452369_4 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000001451 216.0
HKD1_k127_6452369_5 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000007138 206.0
HKD1_k127_6452369_6 ABC-type branched-chain amino acid transport K07121 - - 0.00000000000000000000000000000000000000000000002349 196.0
HKD1_k127_6452369_7 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.00000000000000000000000000007848 133.0
HKD1_k127_6452369_8 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000003243 84.0
HKD1_k127_6470730_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009016 269.0
HKD1_k127_6470730_1 hydrolase activity, acting on ester bonds K07097 - - 0.0000000000000000000000000000000000000003319 169.0
HKD1_k127_647217_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 463.0
HKD1_k127_647217_1 GatB domain K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 414.0
HKD1_k127_6496463_0 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000001204 227.0
HKD1_k127_6496463_1 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.0000000000007903 82.0
HKD1_k127_6496463_2 Tetratricopeptide repeats - - - 0.0002559 44.0
HKD1_k127_6525071_0 histidine--tRNA ligase K01892 GO:0003674,GO:0003824,GO:0004812,GO:0004821,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006427,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009536,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008774 419.0
HKD1_k127_6525071_1 DNA topoisomerase III K03169 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004066 384.0
HKD1_k127_6525071_2 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000001462 209.0
HKD1_k127_6525071_3 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.0000000000000000000000000000000000000000000008852 168.0
HKD1_k127_6525071_4 Zinc metalloprotease (Elastase) K09607 - - 0.00000009396 64.0
HKD1_k127_6539318_0 PFAM ABC transporter K02471 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 479.0
HKD1_k127_6539318_1 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000002084 245.0
HKD1_k127_6539318_2 Guanosine polyphosphate pyrophosphohydrolases synthetases - - - 0.0000000000000000000000000004961 133.0
HKD1_k127_6557393_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 2.57e-281 897.0
HKD1_k127_6557393_1 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 561.0
HKD1_k127_6557393_10 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003423 276.0
HKD1_k127_6557393_11 PFAM Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000004822 249.0
HKD1_k127_6557393_12 Redoxin K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000001526 217.0
HKD1_k127_6557393_13 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000004846 205.0
HKD1_k127_6557393_14 Two component transcriptional regulator, winged helix family - - - 0.0000000000000000000000000000000000000000000000000001193 194.0
HKD1_k127_6557393_15 Member of a two-component regulatory system K07644 - 2.7.13.3 0.000000000000000000000000000000000000000007312 171.0
HKD1_k127_6557393_16 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000003174 142.0
HKD1_k127_6557393_17 Dolichyl-phosphate-mannose-protein mannosyltransferase K07264 - 2.4.2.43 0.00000000000000000000003695 113.0
HKD1_k127_6557393_18 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000008236 101.0
HKD1_k127_6557393_19 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000003192 90.0
HKD1_k127_6557393_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003347 544.0
HKD1_k127_6557393_3 CoA-transferase family III K07544 - 2.8.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 440.0
HKD1_k127_6557393_4 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 447.0
HKD1_k127_6557393_5 PFAM Bacterial extracellular solute-binding K02048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 448.0
HKD1_k127_6557393_6 Protein of unknown function (DUF1298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009007 398.0
HKD1_k127_6557393_7 Binding-protein-dependent transport system inner membrane component K02046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000715 384.0
HKD1_k127_6557393_8 Sulfate ABC transporter, permease K02047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 379.0
HKD1_k127_6557393_9 Phosphate-selective porin O and P K07221 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001761 309.0
HKD1_k127_6575734_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 562.0
HKD1_k127_6575734_1 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III - - - 0.000000000000000000000000000000000000000000000000001007 190.0
HKD1_k127_6575734_2 - - - - 0.00000000000000000000000000000000002834 150.0
HKD1_k127_6575734_3 Transglutaminase-like superfamily - - - 0.00000000000000000000000005305 121.0
HKD1_k127_6601177_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 526.0
HKD1_k127_6601177_1 General secretion pathway protein F K02455,K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005625 362.0
HKD1_k127_6601177_2 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000001013 155.0
HKD1_k127_6601177_3 PFAM Methyltransferase type 11 K03892 - - 0.0000000000000000000000000000005758 131.0
HKD1_k127_6601177_4 Type IV pilus assembly protein PilM; K02461 - - 0.000000000000000000000000000001844 140.0
HKD1_k127_6601177_5 PFAM General secretion pathway protein K K02460 - - 0.0000000000000000002831 103.0
HKD1_k127_6601177_6 Type II secretion system (T2SS), protein M K02462 - - 0.00000000000007488 85.0
HKD1_k127_6618275_0 Proteasomal ATPase OB/ID domain K13527 GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369 - 5.559e-214 680.0
HKD1_k127_6618275_1 Pup-ligase protein K20814 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.119 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 585.0
HKD1_k127_6618275_10 Proteasome subunit K03432 - 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000006631 265.0
HKD1_k127_6618275_11 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000005655 203.0
HKD1_k127_6618275_12 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000005715 201.0
HKD1_k127_6618275_13 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000000003447 180.0
HKD1_k127_6618275_14 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016043,GO:0016829,GO:0016849,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0022607,GO:0034214,GO:0042802,GO:0043170,GO:0043545,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0051259,GO:0061799,GO:0065003,GO:0071704,GO:0071840,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.17 0.000000000000000000000000000000000000000000000003279 190.0
HKD1_k127_6618275_15 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000009451 181.0
HKD1_k127_6618275_16 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000005498 175.0
HKD1_k127_6618275_17 PAS domain containing protein - - - 0.0000000000000000000000000000000000000000008898 175.0
HKD1_k127_6618275_18 ECF sigma factor K03088 - - 0.0000000000000000000000000000003471 132.0
HKD1_k127_6618275_19 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000001318 115.0
HKD1_k127_6618275_2 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 577.0
HKD1_k127_6618275_20 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000001041 109.0
HKD1_k127_6618275_21 - - - - 0.00000000000000000000007139 109.0
HKD1_k127_6618275_22 PilZ domain K02676 - - 0.0000000000000000000002635 102.0
HKD1_k127_6618275_23 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000000001204 102.0
HKD1_k127_6618275_24 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576 3.1.3.27 0.0000000000000003172 91.0
HKD1_k127_6618275_25 Transglycosylase SLT domain - - - 0.00000001959 63.0
HKD1_k127_6618275_26 Pup-like protein K13570 - - 0.0000003675 63.0
HKD1_k127_6618275_27 SCP-2 sterol transfer family protein - - - 0.0009347 51.0
HKD1_k127_6618275_3 electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005103 549.0
HKD1_k127_6618275_4 Pup-ligase protein K13571 GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 6.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008218 534.0
HKD1_k127_6618275_5 Rad51 K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 498.0
HKD1_k127_6618275_6 Rod shape-determining protein K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008261 468.0
HKD1_k127_6618275_7 Competence-damaged protein K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006284 331.0
HKD1_k127_6618275_8 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005484 280.0
HKD1_k127_6618275_9 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019774,GO:0019899,GO:0019941,GO:0030163,GO:0032991,GO:0035375,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001143 268.0
HKD1_k127_6621015_0 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009977 327.0
HKD1_k127_6621015_1 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001548 301.0
HKD1_k127_6621015_2 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000004431 223.0
HKD1_k127_6621015_3 Cupin domain - - - 0.000000000000000000000000000000000000000000000000001817 192.0
HKD1_k127_6621015_4 4-amino-4-deoxy-L-arabinose transferase activity K02277 - 1.9.3.1 0.00000000000000000000000000000000000000000006513 179.0
HKD1_k127_6621015_5 PFAM glycosyl transferase family 39 - - - 0.000000000000000000000000000000000000000005506 173.0
HKD1_k127_6621015_6 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000008519 126.0
HKD1_k127_6621015_7 hydrolase NrgC K22027 - 1.14.13.235 0.000000000000000000000001589 105.0
HKD1_k127_6621015_8 Tetratricopeptide repeat - - - 0.000000000000003859 90.0
HKD1_k127_6621015_9 - - - - 0.000000003405 70.0
HKD1_k127_6626254_0 CYTH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 360.0
HKD1_k127_6626254_1 Phosphohistidine phosphatase SixA K08296 - - 0.00000000000000000000000000000000524 138.0
HKD1_k127_6626510_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002429 284.0
HKD1_k127_6626510_1 PFAM sulfotransferase - - - 0.00000000000000000000000000000000000000000000000000000000006442 227.0
HKD1_k127_6626510_2 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000708 181.0
HKD1_k127_6626510_3 Glycosyl transferases group 1 - - - 0.00009747 47.0
HKD1_k127_6632657_0 Belongs to the amidase family K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 435.0
HKD1_k127_6632657_1 cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004354 284.0
HKD1_k127_6632657_10 - - - - 0.0000001134 61.0
HKD1_k127_6632657_11 PFAM CBS domain - - - 0.0006341 44.0
HKD1_k127_6632657_2 2-hydroxychromene-2-carboxylate isomerase K14584 - 5.99.1.4 0.000000000000000000000000000000000001724 141.0
HKD1_k127_6632657_3 alpha beta - - - 0.0000000000000000000000000000000000368 145.0
HKD1_k127_6632657_4 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000004017 152.0
HKD1_k127_6632657_5 Glutaredoxin - - - 0.000000000000000000000000000000001565 133.0
HKD1_k127_6632657_6 Redoxin - - - 0.0000000000000000000003467 105.0
HKD1_k127_6632657_7 IucA IucC family - - - 0.000000000000002798 89.0
HKD1_k127_6632657_8 histone H2A K63-linked ubiquitination - - - 0.000000001885 68.0
HKD1_k127_6632657_9 LysM domain M23 M37 peptidase domain protein K06194 - - 0.000000008458 67.0
HKD1_k127_6634767_0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 580.0
HKD1_k127_6634767_1 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 488.0
HKD1_k127_6634767_10 Domain of unknown function (DUF1330) - - - 0.0009174 51.0
HKD1_k127_6634767_2 Alkyl sulfatase dimerisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003236 442.0
HKD1_k127_6634767_3 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006824 296.0
HKD1_k127_6634767_4 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000002582 218.0
HKD1_k127_6634767_5 Metalloenzyme superfamily - - - 0.0000000000000000000000000000000000000000000000000002687 211.0
HKD1_k127_6634767_6 Putative member of DMT superfamily (DUF486) K09922 - - 0.0000000000000000000000000000000000000000009942 178.0
HKD1_k127_6634767_7 - - - - 0.000000000000000000000000000000000003766 142.0
HKD1_k127_6634767_8 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000001326 123.0
HKD1_k127_6636921_0 Amylo-alpha-1,6-glucosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006804 601.0
HKD1_k127_6636921_1 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000722 493.0
HKD1_k127_6636921_2 Glucose dehydrogenase C-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 415.0
HKD1_k127_6636921_3 Starch synthase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 312.0
HKD1_k127_6642768_0 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 1.693e-254 812.0
HKD1_k127_6642768_1 belongs to the aldehyde dehydrogenase family K00128,K00129 - 1.2.1.3,1.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 543.0
HKD1_k127_6642768_2 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 394.0
HKD1_k127_6642768_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 338.0
HKD1_k127_6642768_4 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000542 261.0
HKD1_k127_6642768_5 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002829 263.0
HKD1_k127_6642768_6 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000002575 203.0
HKD1_k127_6642768_7 transcriptional regulator - - - 0.000000000001041 77.0
HKD1_k127_6642768_8 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000007654 62.0
HKD1_k127_6644075_0 Sulfate permease family K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 434.0
HKD1_k127_6644075_1 PFAM Band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 422.0
HKD1_k127_6644075_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 336.0
HKD1_k127_6644075_3 converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA - - - 0.00000000000000000000000000000000006264 139.0
HKD1_k127_6644075_4 - - - - 0.000000000000000000000000000003289 129.0
HKD1_k127_6644075_5 NfeD-like C-terminal, partner-binding - - - 0.000000000000000001849 90.0
HKD1_k127_6644075_7 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0005241 49.0
HKD1_k127_6679494_0 aconitate hydratase K01681 - 4.2.1.3 3.781e-314 978.0
HKD1_k127_6679494_1 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007015 428.0
HKD1_k127_6679494_10 Bacterial periplasmic substrate-binding proteins K01713 - 4.2.1.51,4.2.1.91 0.00000001796 60.0
HKD1_k127_6679494_11 N-terminal 7TM region of histidine kinase - - - 0.0001286 55.0
HKD1_k127_6679494_2 Potential Queuosine, Q, salvage protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004397 308.0
HKD1_k127_6679494_3 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.0000000000000000000000000000000000000000000000000000000003538 214.0
HKD1_k127_6679494_4 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000004163 207.0
HKD1_k127_6679494_5 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000001301 169.0
HKD1_k127_6679494_6 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000001052 145.0
HKD1_k127_6679494_7 - - - - 0.0000000000001556 83.0
HKD1_k127_6679494_8 - - - - 0.0000000007086 61.0
HKD1_k127_6679494_9 PFAM ATP-binding region, ATPase domain protein - - - 0.0000000007672 72.0
HKD1_k127_6685583_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 2.317e-224 734.0
HKD1_k127_6685583_1 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 495.0
HKD1_k127_6685583_10 Sulfatase - - - 0.00000000000000000000000000000000003036 151.0
HKD1_k127_6685583_11 - - - - 0.000000000000000000000000000000001038 139.0
HKD1_k127_6685583_12 cheY-homologous receiver domain - - - 0.00000000000000000000000001007 117.0
HKD1_k127_6685583_13 - - - - 0.0000000000000000000001719 107.0
HKD1_k127_6685583_15 Protein of unknown function (DUF1328) - - - 0.000000000003651 72.0
HKD1_k127_6685583_2 Pfam SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 486.0
HKD1_k127_6685583_3 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 346.0
HKD1_k127_6685583_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007739 299.0
HKD1_k127_6685583_5 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000007819 253.0
HKD1_k127_6685583_6 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000001549 222.0
HKD1_k127_6685583_7 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000748 228.0
HKD1_k127_6685583_8 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000001162 205.0
HKD1_k127_6685583_9 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000003714 160.0
HKD1_k127_6695046_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009933 313.0
HKD1_k127_6695046_1 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003304 281.0
HKD1_k127_6695046_2 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000001957 252.0
HKD1_k127_6695046_3 response regulator K02481,K07714,K07715 - - 0.000000000000000000000000000000000000000002215 168.0
HKD1_k127_6695046_4 Polysaccharide biosynthesis/export protein K01991 - - 0.00000000000000000003853 104.0
HKD1_k127_6695046_5 CAAX protease self-immunity K07052 - - 0.000000000000000709 87.0
HKD1_k127_6695046_6 SNARE associated Golgi protein - - - 0.000000000000001506 81.0
HKD1_k127_6695046_7 FHA domain - - - 0.000000000001531 79.0
HKD1_k127_6696383_0 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008656 535.0
HKD1_k127_6696383_1 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000003801 175.0
HKD1_k127_6696383_2 PFAM response regulator receiver K03413 - - 0.00000000000000000000000000000000000000002131 157.0
HKD1_k127_6696383_3 regulator, PATAN and FRGAF domain-containing - - - 0.00000000000000000000000000000001922 145.0
HKD1_k127_6696383_4 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000009362 112.0
HKD1_k127_6696383_5 Two component signalling adaptor domain K03408 - - 0.0000000000000000007956 93.0
HKD1_k127_6696383_6 PFAM CheW domain protein K03408 - - 0.0000000000000016 91.0
HKD1_k127_6696383_8 Protein of unknown function (DUF3426) - - - 0.000005944 57.0
HKD1_k127_6704702_0 Glycosyl transferase family group 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 462.0
HKD1_k127_6704702_1 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 432.0
HKD1_k127_6704702_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000175 271.0
HKD1_k127_6739533_0 Voltage gated chloride channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 627.0
HKD1_k127_6739533_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 466.0
HKD1_k127_6739533_2 Domain of unknown function (DUF4105) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001571 270.0
HKD1_k127_6752864_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 3.601e-204 688.0
HKD1_k127_6752864_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000004142 175.0
HKD1_k127_6752864_2 Dicarboxylate transport - - - 0.000000000000000000000000000000000002425 151.0
HKD1_k127_6752864_3 PFAM isocitrate isopropylmalate dehydrogenase K05824 - 1.1.1.87 0.000000000000000000000003579 105.0
HKD1_k127_6752864_4 Protein conserved in bacteria K09978 - - 0.00000000000000000000009994 106.0
HKD1_k127_6752864_5 WHG domain - - - 0.000000000000000007209 92.0
HKD1_k127_6788362_0 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003,K05685 - - 1.825e-238 777.0
HKD1_k127_6788362_1 PFAM Integral membrane protein TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006372 391.0
HKD1_k127_6788362_2 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 387.0
HKD1_k127_6788362_3 HlyD family secretion protein K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 376.0
HKD1_k127_6788362_4 Transcriptional regulator K03717 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000506 352.0
HKD1_k127_6788362_5 Sugar (and other) transporter K08178 - - 0.00000000000000000000000000000000000006351 160.0
HKD1_k127_6788362_6 PFAM Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000002362 140.0
HKD1_k127_6788362_7 Protein of unknown function (DUF533) - - - 0.000000000000000000000000000003289 129.0
HKD1_k127_6788362_8 CoA-transferase family III - - - 0.0000000003988 61.0
HKD1_k127_6791536_0 cytochrome p450 - GO:0003674,GO:0003824,GO:0004497,GO:0006066,GO:0006629,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008395,GO:0009056,GO:0016042,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016709,GO:0036199,GO:0044238,GO:0044281,GO:0044282,GO:0046164,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616,GO:1902652 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000765 437.0
HKD1_k127_6791536_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008616 333.0
HKD1_k127_6791536_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K15893 - 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001254 285.0
HKD1_k127_6791536_3 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000008406 236.0
HKD1_k127_6791536_4 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000007476 159.0
HKD1_k127_6791536_5 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00001032 60.0
HKD1_k127_6792341_0 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003862 253.0
HKD1_k127_6792341_1 methyltransferase - - - 0.00000000000000000000000000000000003494 143.0
HKD1_k127_6802930_0 General secretory system II, protein E domain protein K02454 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006383 560.0
HKD1_k127_681569_0 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 362.0
HKD1_k127_681569_1 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000009135 160.0
HKD1_k127_681569_2 Domain of unknown function (DUF4388) - - - 0.000000000000000000001566 108.0
HKD1_k127_681569_3 PilZ domain - - - 0.00001019 53.0
HKD1_k127_6828649_0 Ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 391.0
HKD1_k127_6828649_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000006824 158.0
HKD1_k127_6828649_2 PFAM regulatory protein TetR - - - 0.000000000000000000000000000007738 125.0
HKD1_k127_6828649_3 Ferredoxin oxidoreductase K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000007178 133.0
HKD1_k127_6828649_4 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.00000000000000000007969 100.0
HKD1_k127_6836439_0 propanoyl-CoA C-acyltransferase activity K08764 GO:0000038,GO:0000062,GO:0000166,GO:0001676,GO:0002119,GO:0002164,GO:0003008,GO:0003674,GO:0003824,GO:0003988,GO:0005102,GO:0005215,GO:0005319,GO:0005488,GO:0005496,GO:0005504,GO:0005515,GO:0005548,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005777,GO:0005782,GO:0005783,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006163,GO:0006605,GO:0006625,GO:0006629,GO:0006631,GO:0006635,GO:0006637,GO:0006694,GO:0006699,GO:0006700,GO:0006701,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006869,GO:0006886,GO:0006996,GO:0007031,GO:0007275,GO:0007568,GO:0007610,GO:0007611,GO:0007612,GO:0007635,GO:0008104,GO:0008150,GO:0008152,GO:0008202,GO:0008206,GO:0008207,GO:0008289,GO:0008306,GO:0008355,GO:0008525,GO:0008526,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009719,GO:0009725,GO:0009791,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010243,GO:0010817,GO:0010876,GO:0010883,GO:0010888,GO:0010893,GO:0010941,GO:0010942,GO:0012505,GO:0014070,GO:0015031,GO:0015248,GO:0015485,GO:0015711,GO:0015748,GO:0015833,GO:0015850,GO:0015914,GO:0015918,GO:0016020,GO:0016042,GO:0016043,GO:0016053,GO:0016054,GO:0016137,GO:0016138,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0017127,GO:0017144,GO:0019216,GO:0019218,GO:0019222,GO:0019236,GO:0019395,GO:0019637,GO:0019693,GO:0019748,GO:0019751,GO:0019752,GO:0019867,GO:0019898,GO:0022611,GO:0030258,GO:0030301,GO:0030554,GO:0031090,GO:0031312,GO:0031315,GO:0031406,GO:0031907,GO:0031966,GO:0031967,GO:0031968,GO:0031974,GO:0031975,GO:0031981,GO:0032101,GO:0032355,GO:0032368,GO:0032370,GO:0032371,GO:0032373,GO:0032374,GO:0032376,GO:0032377,GO:0032379,GO:0032380,GO:0032382,GO:0032383,GO:0032385,GO:0032386,GO:0032388,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032879,GO:0032934,GO:0032957,GO:0032958,GO:0032959,GO:0032991,GO:0033036,GO:0033218,GO:0033293,GO:0033365,GO:0033540,GO:0033559,GO:0033814,GO:0033865,GO:0033875,GO:0033993,GO:0034032,GO:0034440,GO:0034613,GO:0034641,GO:0034698,GO:0034699,GO:0034754,GO:0035383,GO:0036041,GO:0036042,GO:0036094,GO:0036109,GO:0036314,GO:0036315,GO:0040008,GO:0040012,GO:0040024,GO:0042048,GO:0042180,GO:0042181,GO:0042221,GO:0042445,GO:0042446,GO:0042448,GO:0042579,GO:0042802,GO:0042803,GO:0042810,GO:0042811,GO:0042886,GO:0042981,GO:0043053,GO:0043054,GO:0043065,GO:0043067,GO:0043068,GO:0043167,GO:0043168,GO:0043177,GO:0043178,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043434,GO:0043436,GO:0043574,GO:0043603,GO:0043647,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0044550,GO:0045184,GO:0045540,GO:0045542,GO:0045834,GO:0045927,GO:0045940,GO:0046165,GO:0046173,GO:0046394,GO:0046395,GO:0046483,GO:0046889,GO:0046890,GO:0046907,GO:0046982,GO:0046983,GO:0048037,GO:0048518,GO:0048519,GO:0048522,GO:0048580,GO:0048582,GO:0048583,GO:0048638,GO:0048639,GO:0048856,GO:0050632,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0050810,GO:0050877,GO:0050890,GO:0050896,GO:0050920,GO:0051049,GO:0051050,GO:0051094,GO:0051179,GO:0051186,GO:0051234,GO:0051239,GO:0051240,GO:0051641,GO:0051649,GO:0051716,GO:0055086,GO:0055114,GO:0055115,GO:0060341,GO:0060620,GO:0061062,GO:0061063,GO:0062012,GO:0062013,GO:0065007,GO:0065008,GO:0070013,GO:0070538,GO:0070723,GO:0070727,GO:0070887,GO:0071310,GO:0071396,GO:0071397,GO:0071407,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071981,GO:0072329,GO:0072330,GO:0072521,GO:0072594,GO:0072657,GO:0072659,GO:0072662,GO:0072663,GO:0080090,GO:0090181,GO:0090205,GO:0090407,GO:0097159,GO:0097305,GO:0097306,GO:0097367,GO:0098588,GO:0098805,GO:0106118,GO:0106120,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901373,GO:1901564,GO:1901567,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1901652,GO:1901657,GO:1901659,GO:1901681,GO:1901698,GO:1901700,GO:1901701,GO:1902930,GO:1902932,GO:1904069,GO:1904070,GO:1904109,GO:1904121,GO:1905952,GO:1905953,GO:1905954,GO:1990778,GO:2000026,GO:2000909,GO:2000911 2.3.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 351.0
HKD1_k127_6836439_1 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000002611 241.0
HKD1_k127_6836439_2 MFS/sugar transport protein K03292,K16210 - - 0.00000000000000000000000000000000000000000000000000000000000001462 234.0
HKD1_k127_6836439_3 arylsulfatase A - - - 0.00000000000000000000000000000000000000000000000002075 197.0
HKD1_k127_6836439_4 CYTH K01768,K05873 - 4.6.1.1 0.0000000000000000000000000000002028 132.0
HKD1_k127_689004_0 AMP-binding enzyme C-terminal domain K00666,K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 485.0
HKD1_k127_689004_1 Tryptophan halogenase K20940 - 1.14.13.218 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 470.0
HKD1_k127_689004_10 acetyltransferase - - - 0.000000000000000001294 100.0
HKD1_k127_689004_11 Domain of unknown function (DUF374) K09778 - - 0.000000000000000001588 96.0
HKD1_k127_689004_12 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000001201 68.0
HKD1_k127_689004_13 - - - - 0.000000001563 70.0
HKD1_k127_689004_14 Type II secretory pathway, component - - - 0.000000002464 68.0
HKD1_k127_689004_15 Bacterial regulatory proteins, tetR family - - - 0.00002511 55.0
HKD1_k127_689004_2 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 402.0
HKD1_k127_689004_3 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 324.0
HKD1_k127_689004_4 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005026 284.0
HKD1_k127_689004_5 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily K02617 - - 0.00000000000000000000000000000000000000000001168 180.0
HKD1_k127_689004_6 dehydrogenase complex catalyzes the overall conversion of - - - 0.0000000000000000000000000000000000000000004107 172.0
HKD1_k127_689004_7 Protein of unknown function (DUF1255) - - - 0.0000000000000000000000000000000000000002271 153.0
HKD1_k127_689004_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000226 130.0
HKD1_k127_689004_9 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000002277 112.0
HKD1_k127_6900291_0 Peptidase dimerisation domain K12941 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008017 325.0
HKD1_k127_696405_0 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 362.0
HKD1_k127_696405_1 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000623 327.0
HKD1_k127_696405_2 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005478 289.0
HKD1_k127_696405_3 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000003889 179.0
HKD1_k127_696405_4 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000001573 130.0
HKD1_k127_696405_5 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000000000000005872 106.0
HKD1_k127_696405_6 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000007241 88.0
HKD1_k127_6976063_0 Glutathione S-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007676 286.0
HKD1_k127_6976063_1 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001995 265.0
HKD1_k127_6976063_2 Ferredoxin - - - 0.00000000000000000000000000000006919 128.0
HKD1_k127_6976063_3 COG0859 ADP-heptose LPS heptosyltransferase K02841,K02849 - - 0.0000000000000000000000000003133 133.0
HKD1_k127_6976063_4 - - - - 0.0000000000000000000000000005924 119.0
HKD1_k127_6976063_5 Putative prokaryotic signal transducing protein - - - 0.00000000000000004331 86.0
HKD1_k127_6993709_0 CoA-transferase family III K07749,K08298 - 2.8.3.16,2.8.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004488 427.0
HKD1_k127_6993709_1 4 iron, 4 sulfur cluster binding K00113,K00176,K05524,K13795,K13796 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.1.5.3,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004775 347.0
HKD1_k127_6993709_2 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.00000000000000000000000000000000000000000000000000000576 192.0
HKD1_k127_6993709_3 DoxX family K15977 - - 0.0000000000000000000000000000000000000001305 158.0
HKD1_k127_6993709_4 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000000001155 151.0
HKD1_k127_6993709_5 RF-1 domain K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.0000000000000000000000005838 119.0
HKD1_k127_6993709_6 Belongs to the P-Pant transferase superfamily - - - 0.00000000000000000007159 99.0
HKD1_k127_6993709_7 COG1592 Rubrerythrin - - - 0.00000000001135 64.0
HKD1_k127_6993709_8 - K03286,K07275 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0007214 50.0
HKD1_k127_7018176_0 Amidohydrolase family - - - 1.156e-209 666.0
HKD1_k127_7018176_1 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 534.0
HKD1_k127_7018176_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 313.0
HKD1_k127_7018176_3 cytoskeletal adaptor activity K10380 GO:0002262,GO:0002376,GO:0002520,GO:0003674,GO:0005198,GO:0005200,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005783,GO:0005829,GO:0005856,GO:0005886,GO:0005938,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006887,GO:0006888,GO:0006996,GO:0007010,GO:0007163,GO:0007275,GO:0008092,GO:0008093,GO:0008104,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0010638,GO:0012505,GO:0014731,GO:0015672,GO:0016020,GO:0016043,GO:0016192,GO:0016323,GO:0016528,GO:0016529,GO:0018130,GO:0019438,GO:0019899,GO:0030011,GO:0030016,GO:0030017,GO:0030018,GO:0030097,GO:0030099,GO:0030154,GO:0030218,GO:0030424,GO:0030507,GO:0030673,GO:0030674,GO:0030863,GO:0031252,GO:0031253,GO:0031256,GO:0031430,GO:0031672,GO:0031674,GO:0032501,GO:0032502,GO:0032589,GO:0032940,GO:0033013,GO:0033014,GO:0033036,GO:0033043,GO:0033267,GO:0034101,GO:0034613,GO:0034641,GO:0035088,GO:0035090,GO:0042383,GO:0042592,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043292,GO:0044237,GO:0044249,GO:0044271,GO:0044304,GO:0044422,GO:0044424,GO:0044425,GO:0044444,GO:0044448,GO:0044449,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0045197,GO:0045199,GO:0045202,GO:0045211,GO:0046483,GO:0046903,GO:0046907,GO:0048193,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048534,GO:0048731,GO:0048821,GO:0048856,GO:0048869,GO:0048872,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0051117,GO:0051128,GO:0051130,GO:0051179,GO:0051186,GO:0051188,GO:0051234,GO:0051641,GO:0051649,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0060090,GO:0061245,GO:0061515,GO:0065007,GO:0065008,GO:0070727,GO:0071704,GO:0071840,GO:0071944,GO:0072657,GO:0072659,GO:0097060,GO:0097458,GO:0098590,GO:0098771,GO:0098794,GO:0099080,GO:0099081,GO:0099512,GO:0099568,GO:0120025,GO:0120038,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1990778 - 0.0000000000000000000000000000000000000003184 165.0
HKD1_k127_7018176_4 peptidyl-tyrosine sulfation - - - 0.0002145 49.0
HKD1_k127_7031765_0 COG2124 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 418.0
HKD1_k127_7031765_1 cytochrome p450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 362.0
HKD1_k127_7031765_10 - - - - 0.00000000000000000000000000000673 124.0
HKD1_k127_7031765_11 Transcriptional regulatory protein, C terminal K07658 - - 0.000000000301 62.0
HKD1_k127_7031765_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000005336 251.0
HKD1_k127_7031765_3 Phosphoenolpyruvate phosphomutase - - - 0.000000000000000000000000000000000000000000000000000000000000002617 233.0
HKD1_k127_7031765_4 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000009444 205.0
HKD1_k127_7031765_5 Protein of unknown function (DUF1298) - - - 0.00000000000000000000000000000000000000000000000417 192.0
HKD1_k127_7031765_6 Uncharacterised protein family UPF0066 - - - 0.00000000000000000000000000000000000000000009245 181.0
HKD1_k127_7031765_7 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000003219 169.0
HKD1_k127_7031765_8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000003656 154.0
HKD1_k127_7031765_9 Limonene-12-epoxide hydrolase - - - 0.00000000000000000000000000000000000003271 148.0
HKD1_k127_7038479_0 cytochrome P450 K05917 GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0008150,GO:0008152,GO:0008202,GO:0008398,GO:0016125,GO:0016491,GO:0016705,GO:0016709,GO:0020037,GO:0032451,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046906,GO:0048037,GO:0055114,GO:0070988,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901615 1.14.13.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 473.0
HKD1_k127_7038479_1 Dehydrogenase K00059 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003454 300.0
HKD1_k127_7038479_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009212 281.0
HKD1_k127_7038479_3 Rieske 2Fe-2S K03862 - 1.14.13.82 0.0000000000000000000000000000000000000000000000000000000000000000108 236.0
HKD1_k127_7038479_4 cytochrome p450 - - - 0.000000000000000000000000000000000000000000008988 182.0
HKD1_k127_7038479_5 Divergent 4Fe-4S mono-cluster - - - 0.0000000000001772 72.0
HKD1_k127_7039368_0 ATP-dependent Clp protease ATP-binding subunit ClpA K03694 - - 7.997e-264 838.0
HKD1_k127_7039368_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006803 558.0
HKD1_k127_7039368_10 Domain of unknown function (DUF4388) - - - 0.00000000000000000000003123 113.0
HKD1_k127_7039368_11 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000006667 114.0
HKD1_k127_7039368_12 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000004143 90.0
HKD1_k127_7039368_13 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0042380,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046490,GO:0048037,GO:0051536,GO:0051538,GO:0051540,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.4 0.000000000001637 68.0
HKD1_k127_7039368_14 Protein conserved in bacteria K07114 - - 0.0007574 51.0
HKD1_k127_7039368_2 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004523 458.0
HKD1_k127_7039368_3 Spermidine synthase K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005332 387.0
HKD1_k127_7039368_4 membrane-bound lytic murein transglycosylase K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000577 350.0
HKD1_k127_7039368_5 Peptidogalycan biosysnthesis/recognition K09919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006882 344.0
HKD1_k127_7039368_6 Carboxypeptidase regulatory-like domain K18235 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004804 355.0
HKD1_k127_7039368_7 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 330.0
HKD1_k127_7039368_8 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000005621 215.0
HKD1_k127_7039368_9 PFAM multi antimicrobial extrusion protein MatE - - - 0.0000000000000000000000000000000000000000000001176 188.0
HKD1_k127_7054026_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 468.0
HKD1_k127_7054026_1 ATPase family associated with various cellular activities (AAA) K06027 - 3.6.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000684 313.0
HKD1_k127_7054026_2 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.00000000002034 75.0
HKD1_k127_7061659_0 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 592.0
HKD1_k127_7061659_1 cytochrome P450 K20497 - 1.14.15.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 527.0
HKD1_k127_7061659_2 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 328.0
HKD1_k127_7061659_3 dehydratase - - - 0.00000000000000000000000000000000000000000000000000000005644 205.0
HKD1_k127_7061659_4 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000005391 177.0
HKD1_k127_7061659_5 SCO1 SenC K07152 - - 0.0000000000000000000000000000000000000000001296 171.0
HKD1_k127_7061659_6 Copper chaperone PCu(A)C K09796 - - 0.00000000000000000004939 99.0
HKD1_k127_7061659_7 Domain of Unknown Function (DUF748) - - - 0.0000000000001658 85.0
HKD1_k127_7063322_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - - 2.282e-203 659.0
HKD1_k127_7063322_1 COG1233 Phytoene dehydrogenase and related proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 600.0
HKD1_k127_7063322_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K18688 - 6.2.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 474.0
HKD1_k127_7063322_3 Sulfotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 374.0
HKD1_k127_7063322_4 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 348.0
HKD1_k127_7063322_5 Belongs to the long-chain O-acyltransferase family K00635 GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700 2.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007414 292.0
HKD1_k127_7063322_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005008 272.0
HKD1_k127_7063322_7 peptidoglycan turnover - - - 0.000000000000000000000000000000000000000000000000000000000000000001571 257.0
HKD1_k127_7063322_8 KR domain K07124 - - 0.0000000000000000000000000000000000000000000000000000000001303 215.0
HKD1_k127_7063322_9 Protein of unknown function (DUF2834) - - - 0.00000000000000000000000000000000005323 138.0
HKD1_k127_7069618_0 cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 564.0
HKD1_k127_7069618_1 Conserved Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 563.0
HKD1_k127_7069618_11 transcriptional regulator - - - 0.00000000000000000000000000005016 124.0
HKD1_k127_7069618_12 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000004394 94.0
HKD1_k127_7069618_2 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007904 526.0
HKD1_k127_7069618_3 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000939 392.0
HKD1_k127_7069618_4 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 366.0
HKD1_k127_7069618_5 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 322.0
HKD1_k127_7069618_6 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005227 271.0
HKD1_k127_7069618_7 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000003344 225.0
HKD1_k127_7069618_8 - - - - 0.0000000000000000000000000000000000000000000000000000000003348 219.0
HKD1_k127_7069618_9 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000004525 192.0
HKD1_k127_7070903_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008786 372.0
HKD1_k127_7070903_1 Protein of unknown function (DUF1298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 356.0
HKD1_k127_7070903_2 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003167 277.0
HKD1_k127_7070903_3 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000008882 232.0
HKD1_k127_7070903_5 E1-E2 ATPase K01535 - 3.6.3.6 0.0002263 45.0
HKD1_k127_7070903_6 B12- binding domain protein K01849 - 5.4.99.2 0.0003772 49.0
HKD1_k127_7073206_0 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 361.0
HKD1_k127_7073206_1 ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000005076 248.0
HKD1_k127_7073206_2 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008654,GO:0008661,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0030976,GO:0032787,GO:0034641,GO:0036094,GO:0040007,GO:0042180,GO:0042181,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1901681 2.2.1.7 0.000000000000000000000000000001136 124.0
HKD1_k127_7073206_3 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000005739 123.0
HKD1_k127_7086606_0 COG1960 Acyl-CoA dehydrogenases K00253 - 1.3.8.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 602.0
HKD1_k127_7086606_1 Thiolase, C-terminal domain K00626 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003988,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005777,GO:0005782,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0031907,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0032787,GO:0034440,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:0097159,GO:1901363,GO:1901575 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 594.0
HKD1_k127_7086606_10 enoyl-CoA hydratase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000009818 281.0
HKD1_k127_7086606_11 ABC transporter K02028,K02029,K09972,K10004 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000001463 244.0
HKD1_k127_7086606_2 SMART Integrin alpha beta-propellor repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 504.0
HKD1_k127_7086606_3 Coenzyme A transferase K01039 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 409.0
HKD1_k127_7086606_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007642 411.0
HKD1_k127_7086606_5 Binding-protein-dependent transport system inner membrane component K02029,K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 428.0
HKD1_k127_7086606_6 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 387.0
HKD1_k127_7086606_7 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 327.0
HKD1_k127_7086606_8 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 323.0
HKD1_k127_7086606_9 Acyl CoA acetate 3-ketoacid CoA transferase beta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 323.0
HKD1_k127_7087294_0 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 413.0
HKD1_k127_7087294_1 hemolysin activation secretion protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 419.0
HKD1_k127_7087294_2 CoA-transferase family III K18702 - 2.8.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001862 302.0
HKD1_k127_7087294_3 Acyl- CoA dehydrogenase type 2 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009119 276.0
HKD1_k127_7087294_4 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000001114 181.0
HKD1_k127_7087294_5 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 GO:0005575,GO:0005576 - 0.000000000000000000000000000000000000000000004897 170.0
HKD1_k127_7087294_6 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000002592 119.0
HKD1_k127_7087294_7 - - - - 0.0000000000000000000001645 98.0
HKD1_k127_709442_0 Phospholipase D Transphosphatidylase K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 471.0
HKD1_k127_709442_1 protein involved in response to NO - - - 0.0000000000000000000000000000000000005639 146.0
HKD1_k127_709442_2 lipolytic protein G-D-S-L family - - - 0.000000003282 66.0
HKD1_k127_7105196_0 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000002289 282.0
HKD1_k127_7105196_1 membrane protein required for spore maturation in B.subtilis K06374 - - 0.000000000000000000000000000000000000000000000007132 185.0
HKD1_k127_7105196_2 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 - - 0.00000000000000000001611 105.0
HKD1_k127_7110348_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K18688 - 6.2.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 568.0
HKD1_k127_7110348_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 460.0
HKD1_k127_7110348_10 MobA-like NTP transferase domain K01841,K07281,K07291 - 2.7.7.74,2.7.8.34,5.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000002394 230.0
HKD1_k127_7110348_11 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000008159 213.0
HKD1_k127_7110348_12 MobA-like NTP transferase domain - - - 0.000000000000000000000000000000000000000000000000000008799 202.0
HKD1_k127_7110348_13 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000002271 205.0
HKD1_k127_7110348_14 lipid kinase activity - - - 0.0000000000000000000000000000000000000000002613 181.0
HKD1_k127_7110348_15 Diacylglycerol kinase - - - 0.000000000000000000000000000000000000000003477 177.0
HKD1_k127_7110348_16 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000003103 76.0
HKD1_k127_7110348_17 helix_turn_helix multiple antibiotic resistance protein - - - 0.0004761 48.0
HKD1_k127_7110348_18 sugar transferase - - - 0.0008146 43.0
HKD1_k127_7110348_2 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 411.0
HKD1_k127_7110348_3 Belongs to the thiolase family K08764 GO:0000038,GO:0000062,GO:0000166,GO:0001676,GO:0002119,GO:0002164,GO:0003008,GO:0003674,GO:0003824,GO:0003988,GO:0005102,GO:0005215,GO:0005319,GO:0005488,GO:0005496,GO:0005504,GO:0005515,GO:0005548,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005777,GO:0005782,GO:0005783,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006163,GO:0006605,GO:0006625,GO:0006629,GO:0006631,GO:0006635,GO:0006637,GO:0006694,GO:0006699,GO:0006700,GO:0006701,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006869,GO:0006886,GO:0006996,GO:0007031,GO:0007275,GO:0007568,GO:0007610,GO:0007611,GO:0007612,GO:0007635,GO:0008104,GO:0008150,GO:0008152,GO:0008202,GO:0008206,GO:0008207,GO:0008289,GO:0008306,GO:0008355,GO:0008525,GO:0008526,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009719,GO:0009725,GO:0009791,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010243,GO:0010817,GO:0010876,GO:0010883,GO:0010888,GO:0010893,GO:0010941,GO:0010942,GO:0012505,GO:0014070,GO:0015031,GO:0015248,GO:0015485,GO:0015711,GO:0015748,GO:0015833,GO:0015850,GO:0015914,GO:0015918,GO:0016020,GO:0016042,GO:0016043,GO:0016053,GO:0016054,GO:0016137,GO:0016138,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0017127,GO:0017144,GO:0019216,GO:0019218,GO:0019222,GO:0019236,GO:0019395,GO:0019637,GO:0019693,GO:0019748,GO:0019751,GO:0019752,GO:0019867,GO:0019898,GO:0022611,GO:0030258,GO:0030301,GO:0030554,GO:0031090,GO:0031312,GO:0031315,GO:0031406,GO:0031907,GO:0031966,GO:0031967,GO:0031968,GO:0031974,GO:0031975,GO:0031981,GO:0032101,GO:0032355,GO:0032368,GO:0032370,GO:0032371,GO:0032373,GO:0032374,GO:0032376,GO:0032377,GO:0032379,GO:0032380,GO:0032382,GO:0032383,GO:0032385,GO:0032386,GO:0032388,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032879,GO:0032934,GO:0032957,GO:0032958,GO:0032959,GO:0032991,GO:0033036,GO:0033218,GO:0033293,GO:0033365,GO:0033540,GO:0033559,GO:0033814,GO:0033865,GO:0033875,GO:0033993,GO:0034032,GO:0034440,GO:0034613,GO:0034641,GO:0034698,GO:0034699,GO:0034754,GO:0035383,GO:0036041,GO:0036042,GO:0036094,GO:0036109,GO:0036314,GO:0036315,GO:0040008,GO:0040012,GO:0040024,GO:0042048,GO:0042180,GO:0042181,GO:0042221,GO:0042445,GO:0042446,GO:0042448,GO:0042579,GO:0042802,GO:0042803,GO:0042810,GO:0042811,GO:0042886,GO:0042981,GO:0043053,GO:0043054,GO:0043065,GO:0043067,GO:0043068,GO:0043167,GO:0043168,GO:0043177,GO:0043178,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043434,GO:0043436,GO:0043574,GO:0043603,GO:0043647,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0044550,GO:0045184,GO:0045540,GO:0045542,GO:0045834,GO:0045927,GO:0045940,GO:0046165,GO:0046173,GO:0046394,GO:0046395,GO:0046483,GO:0046889,GO:0046890,GO:0046907,GO:0046982,GO:0046983,GO:0048037,GO:0048518,GO:0048519,GO:0048522,GO:0048580,GO:0048582,GO:0048583,GO:0048638,GO:0048639,GO:0048856,GO:0050632,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0050810,GO:0050877,GO:0050890,GO:0050896,GO:0050920,GO:0051049,GO:0051050,GO:0051094,GO:0051179,GO:0051186,GO:0051234,GO:0051239,GO:0051240,GO:0051641,GO:0051649,GO:0051716,GO:0055086,GO:0055114,GO:0055115,GO:0060341,GO:0060620,GO:0061062,GO:0061063,GO:0062012,GO:0062013,GO:0065007,GO:0065008,GO:0070013,GO:0070538,GO:0070723,GO:0070727,GO:0070887,GO:0071310,GO:0071396,GO:0071397,GO:0071407,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071981,GO:0072329,GO:0072330,GO:0072521,GO:0072594,GO:0072657,GO:0072659,GO:0072662,GO:0072663,GO:0080090,GO:0090181,GO:0090205,GO:0090407,GO:0097159,GO:0097305,GO:0097306,GO:0097367,GO:0098588,GO:0098805,GO:0106118,GO:0106120,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901373,GO:1901564,GO:1901567,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1901652,GO:1901657,GO:1901659,GO:1901681,GO:1901698,GO:1901700,GO:1901701,GO:1902930,GO:1902932,GO:1904069,GO:1904070,GO:1904109,GO:1904121,GO:1905952,GO:1905953,GO:1905954,GO:1990778,GO:2000026,GO:2000909,GO:2000911 2.3.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006779 368.0
HKD1_k127_7110348_4 OST-HTH/LOTUS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007607 360.0
HKD1_k127_7110348_5 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 316.0
HKD1_k127_7110348_6 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 291.0
HKD1_k127_7110348_7 CDP-alcohol phosphatidyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004655 306.0
HKD1_k127_7110348_8 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003626 287.0
HKD1_k127_7110348_9 acid phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000002389 262.0
HKD1_k127_7152137_0 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000009276 201.0
HKD1_k127_7152137_1 protein conserved in bacteria K09793 - - 0.00000000000000000000000000000000000000000004122 166.0
HKD1_k127_7152137_2 Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000001085 81.0
HKD1_k127_7156671_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 372.0
HKD1_k127_7156671_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 291.0
HKD1_k127_7156671_2 Bacterial regulatory protein, Fis family K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006584 283.0
HKD1_k127_7156671_3 PFAM MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000001356 163.0
HKD1_k127_7156671_4 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.00000000000000000000000000000002542 130.0
HKD1_k127_7156671_5 TolB amino-terminal domain K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.0000000000000000000000003579 121.0
HKD1_k127_7156671_6 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.0000000000000000000007317 98.0
HKD1_k127_7156671_7 FHA domain - - - 0.00000000000000000003306 102.0
HKD1_k127_7156671_8 COG2133 Glucose sorbosone dehydrogenases - - - 0.0000000002685 68.0
HKD1_k127_7156671_9 TonB C terminal K03646 - - 0.00000001694 64.0
HKD1_k127_7159387_0 KR domain K07124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 322.0
HKD1_k127_7159387_1 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000008566 221.0
HKD1_k127_7159387_2 epimerase, PhzC PhzF homolog K06998 - 5.3.3.17 0.00000000000000000000000000000001717 133.0
HKD1_k127_7159387_3 carbohydrate metabolic process - - - 0.0000000000000000000003011 106.0
HKD1_k127_7160024_0 GXGXG motif K00265 - 1.4.1.13,1.4.1.14 0.0 1693.0
HKD1_k127_7160024_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 4.514e-206 652.0
HKD1_k127_7160024_10 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0030272,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 0.000000000000000000002415 105.0
HKD1_k127_7160024_11 - - - - 0.000003476 48.0
HKD1_k127_7160024_12 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000738 50.0
HKD1_k127_7160024_2 glutamate synthase K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 589.0
HKD1_k127_7160024_3 Luciferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 453.0
HKD1_k127_7160024_4 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 419.0
HKD1_k127_7160024_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 326.0
HKD1_k127_7160024_6 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005489 294.0
HKD1_k127_7160024_7 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000002163 152.0
HKD1_k127_7160024_8 helix_turn_helix ASNC type K03719 - - 0.0000000000000000000000000000005765 129.0
HKD1_k127_7160024_9 - - - - 0.00000000000000000000000003202 111.0
HKD1_k127_7172413_0 AAA-like domain - - - 3.681e-243 796.0
HKD1_k127_7172413_1 N-acyl-D-aspartate D-glutamate deacylase - - - 5.417e-217 695.0
HKD1_k127_7172413_2 Short chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 324.0
HKD1_k127_7172413_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01885,K01894 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000001262 240.0
HKD1_k127_7172413_4 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.000000000000000000000000000000000000000000000000000000001857 207.0
HKD1_k127_7172413_5 Rieske-like [2Fe-2S] domain K05710 - - 0.000000000004482 77.0
HKD1_k127_7172413_6 Dienelactone hydrolase family - - - 0.000000001802 68.0
HKD1_k127_7172413_7 nucleoside 2-deoxyribosyltransferase - - - 0.00000004005 59.0
HKD1_k127_717850_0 Phosphohydrolase-associated domain K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 374.0
HKD1_k127_717850_1 aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 376.0
HKD1_k127_717850_2 Domain of unknown function (DUF4465) - - - 0.0000000000000000000000000000000000000000000000000000007338 203.0
HKD1_k127_717850_3 Pkd domain containing protein - - - 0.00000000000000000000000000000000000000000003852 173.0
HKD1_k127_717850_4 TonB-dependent receptor K16092 - - 0.000000000000000000000000000000000000001584 168.0
HKD1_k127_717850_5 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000001785 126.0
HKD1_k127_717850_6 - - - - 0.0009807 51.0
HKD1_k127_7178840_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 475.0
HKD1_k127_7178840_1 Lysin motif K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004361 449.0
HKD1_k127_7178840_2 CoA carboxylase activity K01965,K02160 - 6.4.1.3 0.000000000000002849 90.0
HKD1_k127_7178840_3 Acetyltransferase (GNAT) domain - - - 0.000014 56.0
HKD1_k127_7194454_0 56kDa selenium binding protein (SBP56) K17285 - - 1.102e-221 699.0
HKD1_k127_7194454_1 PFAM Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000007023 209.0
HKD1_k127_7194454_2 Lipoate-protein ligase - - - 0.00000000000000000000000000000000001372 155.0
HKD1_k127_7194454_3 Methyltransferase fkbm family - - - 0.0000000000000000000000000000002544 132.0
HKD1_k127_7194454_4 Methyltransferase FkbM domain - - - 0.00000000000000007374 94.0
HKD1_k127_7194454_5 Sulfotransferase family - - - 0.0000000000000006883 92.0
HKD1_k127_7199138_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005401 527.0
HKD1_k127_7199138_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 380.0
HKD1_k127_7199138_10 outer membrane efflux protein - - - 0.0000000000000000000000000000001768 141.0
HKD1_k127_7199138_11 PTS system fructose IIA component K02793 - 2.7.1.191 0.0000000000000000000000000000006308 138.0
HKD1_k127_7199138_12 Polymer-forming cytoskeletal - - - 0.00000000000000000006819 96.0
HKD1_k127_7199138_13 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.00000000000000002282 87.0
HKD1_k127_7199138_14 COG1925 Phosphotransferase system, HPr-related proteins K08485,K11189 GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006808,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009401,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050896,GO:0051179,GO:0051234,GO:0065007,GO:0071702,GO:0071704,GO:1901564,GO:1901698 - 0.000000000000008822 82.0
HKD1_k127_7199138_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005612 332.0
HKD1_k127_7199138_3 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003793 266.0
HKD1_k127_7199138_4 SecD/SecF GG Motif K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000117 232.0
HKD1_k127_7199138_5 PFAM Stage II sporulation D domain protein K06381 - - 0.00000000000000000000000000000000000000000000000001364 204.0
HKD1_k127_7199138_6 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000008308 188.0
HKD1_k127_7199138_7 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000478 166.0
HKD1_k127_7199138_8 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000000000000000000000724 159.0
HKD1_k127_7199138_9 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.00000000000000000000000000000000003495 149.0
HKD1_k127_7207279_0 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 394.0
HKD1_k127_7207279_1 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 323.0
HKD1_k127_7207279_2 PLD-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001469 274.0
HKD1_k127_7207279_3 - - - - 0.00000000000000000000000000000000000000004003 165.0
HKD1_k127_7207279_4 - - - - 0.000000000000000000000000000000000997 149.0
HKD1_k127_7207279_5 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000001024 143.0
HKD1_k127_7207279_6 Domain of unknown function (DUF4956) - - - 0.00000000000000001122 93.0
HKD1_k127_7207279_7 - - - - 0.00000002763 65.0
HKD1_k127_7213694_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 505.0
HKD1_k127_7213694_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005253 400.0
HKD1_k127_7213694_2 cytochrome P-450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 376.0
HKD1_k127_7213694_3 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.0000000000003905 82.0
HKD1_k127_7213694_4 Smr protein MutS2 - GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.0002323 46.0
HKD1_k127_7217211_0 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 514.0
HKD1_k127_7217211_1 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 526.0
HKD1_k127_7217211_10 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000001092 144.0
HKD1_k127_7217211_11 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000000003182 156.0
HKD1_k127_7217211_12 phosphatase homologous to the C-terminal domain of histone macroH2A1 - - - 0.0000000000000000000000000000000000005159 147.0
HKD1_k127_7217211_13 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000001286 126.0
HKD1_k127_7217211_14 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000004718 115.0
HKD1_k127_7217211_15 Cytochrome c assembly protein - - - 0.000000000000000000009795 102.0
HKD1_k127_7217211_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 365.0
HKD1_k127_7217211_3 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 328.0
HKD1_k127_7217211_4 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000003569 256.0
HKD1_k127_7217211_5 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000001031 204.0
HKD1_k127_7217211_6 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000002798 183.0
HKD1_k127_7217211_7 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000003649 172.0
HKD1_k127_7217211_8 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000001771 168.0
HKD1_k127_7217211_9 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000002412 180.0
HKD1_k127_7231509_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.491e-247 781.0
HKD1_k127_7231509_1 Uncharacterized protein family (UPF0051) K09014 - - 1.465e-244 775.0
HKD1_k127_7231509_10 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008514 300.0
HKD1_k127_7231509_11 Acyl-protein synthetase, LuxE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000262 288.0
HKD1_k127_7231509_12 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005962 297.0
HKD1_k127_7231509_13 DnaJ C terminal domain K03686,K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005113 263.0
HKD1_k127_7231509_14 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 0.0000000000000000000000000000000000000000000000000000000000000000000001556 258.0
HKD1_k127_7231509_15 Sulfotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000007079 239.0
HKD1_k127_7231509_16 SUF system FeS assembly protein, NifU family K04488 - - 0.00000000000000000000000000000000000000000000000001848 183.0
HKD1_k127_7231509_17 transcriptional regulator, Rrf2 family - - - 0.000000000000000000000000000000005161 148.0
HKD1_k127_7231509_18 belongs to the aldehyde dehydrogenase family K03400 - 1.2.1.50 0.00000000000000000000000000000003955 145.0
HKD1_k127_7231509_19 Iron-sulfur cluster assembly protein - - - 0.0000000000000000000000000000003733 134.0
HKD1_k127_7231509_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 6.1.1.15 1.195e-229 727.0
HKD1_k127_7231509_22 NAD(P)H-binding K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000005719 102.0
HKD1_k127_7231509_23 Amino-transferase class IV K00826 - 2.6.1.42 0.00000000000000004445 83.0
HKD1_k127_7231509_24 Major Facilitator Superfamily - - - 0.00000000001597 76.0
HKD1_k127_7231509_25 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.6.1.19,2.6.1.22 0.0009687 42.0
HKD1_k127_7231509_3 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000271 514.0
HKD1_k127_7231509_4 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 522.0
HKD1_k127_7231509_5 Domain of unknown function (DUF4070) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005549 435.0
HKD1_k127_7231509_6 FeS assembly ATPase SufC K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 369.0
HKD1_k127_7231509_7 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 350.0
HKD1_k127_7231509_8 FeS assembly protein SufD K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 339.0
HKD1_k127_7231509_9 Putative zinc-binding metallo-peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005421 312.0
HKD1_k127_7252459_0 cytochrome P450 K05917 GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0008150,GO:0008152,GO:0008202,GO:0008398,GO:0016125,GO:0016491,GO:0016705,GO:0016709,GO:0020037,GO:0032451,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046906,GO:0048037,GO:0055114,GO:0070988,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901615 1.14.13.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 536.0
HKD1_k127_7252459_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000002622 236.0
HKD1_k127_7252459_2 - - - - 0.00000000000000000000000000000000000000000000000000007575 209.0
HKD1_k127_7252459_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000000000000000000003175 184.0
HKD1_k127_7260748_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K15868 - 6.2.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007555 546.0
HKD1_k127_7260748_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000009287 100.0
HKD1_k127_7260748_2 Heavy-metal resistance - - - 0.00000001207 66.0
HKD1_k127_7263071_0 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007614 435.0
HKD1_k127_7263071_1 Phospholipid methyltransferase - - - 0.000000000000000000000000000000000000000000000003807 187.0
HKD1_k127_7263071_2 Acetyltransferase (GNAT) domain K02348 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 - 0.0000000000000000000000000001235 121.0
HKD1_k127_7263071_3 Transglycosylase associated protein - - - 0.0000000000000000000000000001336 121.0
HKD1_k127_7263071_4 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000001055 100.0
HKD1_k127_7263071_5 BolA-like protein K05527,K22066 GO:0006807,GO:0008150,GO:0008152,GO:0010467,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0071704,GO:0097428,GO:0106035,GO:1901564 - 0.000000000000000000001124 104.0
HKD1_k127_7263071_6 - - - - 0.0000000003178 65.0
HKD1_k127_7266493_0 PFAM peptidase S15 K06978 - - 2.823e-225 717.0
HKD1_k127_7266493_1 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 349.0
HKD1_k127_7266493_10 Domain of unknown function (DUF1330) - - - 0.00000000000008884 83.0
HKD1_k127_7266493_11 - - - - 0.0000000002504 69.0
HKD1_k127_7266493_12 protein conserved in bacteria K09930 - - 0.000000002107 64.0
HKD1_k127_7266493_13 - - - - 0.000000003842 61.0
HKD1_k127_7266493_14 peptidyl-tyrosine sulfation - - - 0.00000007156 57.0
HKD1_k127_7266493_2 Protein of unknown function (DUF692) K09930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 325.0
HKD1_k127_7266493_3 PFAM O-methyltransferase family 2 K09846 - 2.1.1.210 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007171 309.0
HKD1_k127_7266493_4 PFAM Integral membrane protein TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001884 283.0
HKD1_k127_7266493_5 Enoyl-CoA hydratase/isomerase K01692,K13766 - 4.2.1.17,4.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000002828 264.0
HKD1_k127_7266493_6 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000007198 204.0
HKD1_k127_7266493_7 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000002374 178.0
HKD1_k127_7266493_8 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain - - - 0.00000000000000000000000000000000000000000000000642 179.0
HKD1_k127_7266493_9 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000001236 124.0
HKD1_k127_7266920_0 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 434.0
HKD1_k127_7266920_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000001693 215.0
HKD1_k127_7266920_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000003646 178.0
HKD1_k127_7266920_3 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000001501 128.0
HKD1_k127_7273728_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006366 565.0
HKD1_k127_7273728_1 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000000000004724 240.0
HKD1_k127_7273728_2 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000437 142.0
HKD1_k127_7273728_3 PFAM YbbR family protein - - - 0.0000000000000000000000003044 114.0
HKD1_k127_7282866_0 PFAM AMP-dependent synthetase and ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004517 523.0
HKD1_k127_7282866_1 epoxide hydrolase K01253 - 3.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005997 472.0
HKD1_k127_7282866_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009305 316.0
HKD1_k127_7282866_3 Protein of unknown function (DUF455) K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000001187 183.0
HKD1_k127_7282866_4 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000000000000000000003866 186.0
HKD1_k127_7282866_5 PFAM NAD dependent epimerase dehydratase family K01710,K01784 - 4.2.1.46,5.1.3.2 0.000000000000000000000000000000000006463 157.0
HKD1_k127_7282866_6 - - - - 0.0000000000000926 79.0
HKD1_k127_7317549_0 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K21142 - 2.8.1.12 0.000000000000000000000000000000000000000000000004689 189.0
HKD1_k127_7317549_1 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.000000000000000000000000000000000000000000002055 171.0
HKD1_k127_7317549_2 signal transduction histidine kinase K02668,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000007099 170.0
HKD1_k127_7317549_3 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.000000000000000000000000000000000000002865 166.0
HKD1_k127_7317549_4 Polymer-forming cytoskeletal - - - 0.000000000000000000005859 101.0
HKD1_k127_7317549_5 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000006433 93.0
HKD1_k127_7317549_6 Peptidase MA superfamily - - - 0.0000000000002069 83.0
HKD1_k127_7317549_7 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000007362 75.0
HKD1_k127_7317549_8 Protein of unknown function (DUF2834) - - - 0.00000001134 66.0
HKD1_k127_7320314_0 PAS domain K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 623.0
HKD1_k127_7320314_1 response regulator K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 524.0
HKD1_k127_7334331_0 serine-type endopeptidase activity K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000001248 278.0
HKD1_k127_7334331_1 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000001165 139.0
HKD1_k127_7334331_2 Galactokinase galactose-binding signature K00849 - 2.7.1.6 0.0000000000000000000000004179 108.0
HKD1_k127_7334331_3 Stress-responsive transcriptional regulator - - - 0.00000000000002351 86.0
HKD1_k127_7334331_4 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000006188 53.0
HKD1_k127_7410944_0 polysaccharide catabolic process K05991 - 3.2.1.123 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 399.0
HKD1_k127_7410944_1 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000001128 86.0
HKD1_k127_7415734_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713,K19641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008948 337.0
HKD1_k127_7415734_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000005552 106.0
HKD1_k127_7415734_2 Histidine kinase - - - 0.000000000000000000006437 103.0
HKD1_k127_7416156_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 293.0
HKD1_k127_7416156_1 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002239 262.0
HKD1_k127_7416156_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000002213 256.0
HKD1_k127_7416156_3 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000002765 246.0
HKD1_k127_7416156_4 Peptidase C26 K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000006256 243.0
HKD1_k127_7416156_5 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000001065 193.0
HKD1_k127_7416156_6 rRNA methyltransferase - - - 0.000000000000000000000000000000000000000000001275 180.0
HKD1_k127_7416156_7 Protein of unknown function, DUF393 - - - 0.0000000000000000000000000000002005 127.0
HKD1_k127_7416156_8 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000007467 102.0
HKD1_k127_7416156_9 fibroblast growth factor binding - - - 0.00004474 56.0
HKD1_k127_7427552_0 Glutathione S-transferase, C-terminal domain K00799,K03599 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 337.0
HKD1_k127_7427552_1 GMC oxidoreductase K06151 - 1.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000004028 281.0
HKD1_k127_7427552_2 asparagine synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000595 268.0
HKD1_k127_7427552_3 Gluconate 2-dehydrogenase K06152 - 1.1.99.3 0.0000000000001631 83.0
HKD1_k127_7427552_4 General secretion pathway protein C K02452 - - 0.00002319 58.0
HKD1_k127_7431984_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004909 412.0
HKD1_k127_7431984_1 aminotransferase class I and II - - - 0.000000000000000000000000000000000000001517 155.0
HKD1_k127_7435412_0 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 1.407e-278 881.0
HKD1_k127_7435412_1 Belongs to the RtcB family K14415 - 6.5.1.3 6.227e-195 631.0
HKD1_k127_7435412_10 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000006485 123.0
HKD1_k127_7435412_11 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.000000000000000000000000004561 118.0
HKD1_k127_7435412_12 HEPN domain - - - 0.0000000000000000000004194 106.0
HKD1_k127_7435412_13 Archease protein family (MTH1598/TM1083) - - - 0.0000000000004354 83.0
HKD1_k127_7435412_14 ORF6N domain - - - 0.0000000000125 68.0
HKD1_k127_7435412_15 PFAM DNA polymerase beta domain protein region - - - 0.000000002314 70.0
HKD1_k127_7435412_16 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000001704 52.0
HKD1_k127_7435412_17 Putative bacterial sensory transduction regulator - - - 0.000005039 57.0
HKD1_k127_7435412_2 S-Adenosylmethionine synthetase K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 381.0
HKD1_k127_7435412_3 acetyl-coa acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006369 360.0
HKD1_k127_7435412_4 HlyD family secretion protein K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009972 369.0
HKD1_k127_7435412_5 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008555 332.0
HKD1_k127_7435412_6 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001853 313.0
HKD1_k127_7435412_7 SEC-C Motif Domain Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000287 258.0
HKD1_k127_7435412_8 Alpha beta hydrolase K01066 - - 0.00000000000000000000000000000000000000000002348 177.0
HKD1_k127_7435412_9 ABC transporter K02003 - - 0.0000000000000000000000000000002828 124.0
HKD1_k127_7460446_0 amidohydrolase - - - 2.77e-205 656.0
HKD1_k127_7460446_1 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005598 490.0
HKD1_k127_7460446_2 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 361.0
HKD1_k127_7460446_3 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000007 179.0
HKD1_k127_7460446_4 arylsulfatase activity - - - 0.000000000000000000000000000000000000000003919 177.0
HKD1_k127_7460446_5 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000001974 117.0
HKD1_k127_7460446_6 - - - - 0.000000000003408 72.0
HKD1_k127_7460446_7 - - - - 0.00007977 49.0
HKD1_k127_7462338_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 1.99e-238 762.0
HKD1_k127_7462338_1 Carbohydrate phosphorylase K00688 - 2.4.1.1 3.268e-224 727.0
HKD1_k127_7462338_2 transferase activity, transferring glycosyl groups K02844 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0008653,GO:0008919,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0046527,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006506 343.0
HKD1_k127_7462338_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000571 97.0
HKD1_k127_7462338_4 Thiamine-binding protein - - - 0.0000000000001911 74.0
HKD1_k127_7462338_5 Belongs to the CDS family K00981,K19664 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41,2.7.7.67 0.000000000002861 80.0
HKD1_k127_7463750_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 507.0
HKD1_k127_7463750_1 16S rRNA methyltransferase RsmB/F K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004058 375.0
HKD1_k127_7463750_10 CAAX protease self-immunity K07052 - - 0.00000000000000000001307 101.0
HKD1_k127_7463750_11 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000001342 101.0
HKD1_k127_7463750_13 Fibronectin type 3 domain K01179,K06882 - 3.2.1.4 0.0003977 53.0
HKD1_k127_7463750_2 Sterol-sensing domain of SREBP cleavage-activation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004301 301.0
HKD1_k127_7463750_3 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000001668 276.0
HKD1_k127_7463750_4 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000004647 257.0
HKD1_k127_7463750_5 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000002066 213.0
HKD1_k127_7463750_6 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000001084 184.0
HKD1_k127_7463750_7 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000001489 176.0
HKD1_k127_7463750_8 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000001353 145.0
HKD1_k127_7463750_9 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000002799 129.0
HKD1_k127_7464509_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 462.0
HKD1_k127_7464509_1 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 354.0
HKD1_k127_7464509_2 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006103 252.0
HKD1_k127_7464509_3 glutathione transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000002718 215.0
HKD1_k127_7464509_4 Polyribonucleotide nucleotidyltransferase - - - 0.000000000000000000004646 101.0
HKD1_k127_7464509_5 - - - - 0.00000001805 66.0
HKD1_k127_7473686_0 Methionine synthase K00548 - 2.1.1.13 0.0 1688.0
HKD1_k127_7473686_1 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000282 249.0
HKD1_k127_7473686_2 TIGRFAM RarD protein, DMT superfamily transporter K05786 - - 0.00000000000000000000000000000000000000000000000000000000000000003455 239.0
HKD1_k127_7473686_3 Protein of unknown function DUF99 K09120 - - 0.00000000000000000000000000000000000000000000000001456 185.0
HKD1_k127_7473686_4 PFAM VacJ family lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000005652 183.0
HKD1_k127_7473686_5 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000000000000000002525 178.0
HKD1_k127_7473686_6 Protein of unknown function (DUF541) - - - 0.0000000000000000000000000000003391 133.0
HKD1_k127_7473686_7 MlaC protein K07323 - - 0.0000000000000000000000001332 116.0
HKD1_k127_7473686_8 PFAM Mammalian cell entry related domain protein K02067 - - 0.0000000000000000000000005871 106.0
HKD1_k127_7487292_0 beta-N-acetylhexosaminidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 560.0
HKD1_k127_7487292_1 Lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 366.0
HKD1_k127_7487292_2 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005376 246.0
HKD1_k127_7487292_3 Amidohydrolase K07046 - - 0.00000000000000000000000000000000000000000000000000000000000000000005919 240.0
HKD1_k127_7487292_4 NnrS protein K07234 - - 0.00000000000000000000000000000000000000001945 166.0
HKD1_k127_7487292_6 luxR family - - - 0.00000000000000000000000000000001677 145.0
HKD1_k127_7491690_0 Calcineurin-like phosphoesterase K03651 - 3.1.4.53 0.0000000000000000000000000000000000001448 156.0
HKD1_k127_7491690_1 Pfam:N_methyl_2 K02650 - - 0.0000000000000000000008936 104.0
HKD1_k127_7491690_2 Major Facilitator Superfamily K03301 - - 0.00000000005567 76.0
HKD1_k127_7491690_3 Glycosyltransferase like family 2 - - - 0.000003731 55.0
HKD1_k127_7509019_0 arylsulfatase activity - - - 0.000000000000000000000000000000000000003257 164.0
HKD1_k127_7509019_1 TonB dependent receptor K02014 - - 0.000000000000000000001563 103.0
HKD1_k127_7509019_2 repeat-containing protein - - - 0.000000007988 70.0
HKD1_k127_7511453_0 ABC transporter K05847 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008494 334.0
HKD1_k127_7511453_1 lipopolysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001616 258.0
HKD1_k127_7511453_2 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.0000000000000000000000000000000000000000000000000000000000005031 216.0
HKD1_k127_7545918_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 421.0
HKD1_k127_7545918_1 major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 403.0
HKD1_k127_7545918_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000003237 221.0
HKD1_k127_7549461_0 Zinc-binding dehydrogenase K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008122 404.0
HKD1_k127_7549461_1 Protein of unknown function (DUF2868) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002261 267.0
HKD1_k127_7549461_2 Pfam:DUF385 - - - 0.0000000000000000000000000000002377 127.0
HKD1_k127_7549461_3 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000001902 130.0
HKD1_k127_7549461_4 GTP-binding protein - - - 0.0000000000000000000000006726 121.0
HKD1_k127_7597905_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate - - - 0.0 1050.0
HKD1_k127_7597905_1 Universal stress protein family - - - 0.000000000000000000000000000001175 132.0
HKD1_k127_7597905_2 exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.0000000000000000000000000001372 117.0
HKD1_k127_7602688_0 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 409.0
HKD1_k127_7602688_1 COG2084 3-hydroxyisobutyrate dehydrogenase and related K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 408.0
HKD1_k127_7602688_2 COG2211 Na melibiose symporter and related transporters - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009906 275.0
HKD1_k127_7606854_0 glutamine synthetase K01915 - 6.3.1.2 1.698e-215 679.0
HKD1_k127_7606854_1 Belongs to the P(II) protein family K04751 GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772 - 0.00000000000000000000000000000000000000000000000000002449 190.0
HKD1_k127_7606854_2 molybdenum cofactor guanylyltransferase activity K03752,K13818 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.77 0.0000000000000000000000000000000000000002264 162.0
HKD1_k127_7606854_3 Belongs to the GcvT family K06980 - - 0.000000000000000000000000000000005887 149.0
HKD1_k127_7606854_4 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.000000000000000000000000000006744 137.0
HKD1_k127_7606854_5 Universal stress protein family - - - 0.0000000000000000000003063 104.0
HKD1_k127_761047_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 560.0
HKD1_k127_761047_1 ABC1 family - - - 0.0000000000000000000000000000000000000000000000000000001553 213.0
HKD1_k127_761047_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01896 GO:0003674,GO:0003824,GO:0003996,GO:0004321,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0015645,GO:0016053,GO:0016405,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0016874,GO:0016877,GO:0016878,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901576 6.2.1.1,6.2.1.2 0.00000000000000000000000000000000000003679 144.0
HKD1_k127_761047_3 Photosynthesis system II assembly factor YCF48 - - - 0.00000000000000000000029 111.0
HKD1_k127_761047_4 cellulose binding - - - 0.000003894 59.0
HKD1_k127_764425_0 response regulator K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000532 379.0
HKD1_k127_764425_1 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 333.0
HKD1_k127_7649274_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 472.0
HKD1_k127_7649274_1 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 438.0
HKD1_k127_7649274_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003678 242.0
HKD1_k127_7649274_3 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000005868 205.0
HKD1_k127_7672585_0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00058,K11216 - 1.1.1.399,1.1.1.95,2.7.1.189 9.875e-245 790.0
HKD1_k127_7672585_1 COG2723 Beta-glucosidase 6-phospho-beta-glucosidase beta- galactosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 507.0
HKD1_k127_7672585_10 energy transducer activity K03832 - - 0.0007 43.0
HKD1_k127_7672585_2 Belongs to the pyruvate kinase family K00873 GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 420.0
HKD1_k127_7672585_3 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001189 296.0
HKD1_k127_7672585_4 fatty acid desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000005043 243.0
HKD1_k127_7672585_5 Pfam Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000004617 233.0
HKD1_k127_7672585_6 PaaX-like protein C-terminal domain - - - 0.0000000000000000000000000000000000000000000000001903 186.0
HKD1_k127_7672585_7 eight transmembrane protein EpsH - - - 0.00000000000000000000000000008237 127.0
HKD1_k127_7672585_8 protein-(glutamine-N5) methyltransferase activity - - - 0.00000000000000000000000491 104.0
HKD1_k127_7672585_9 Polymer-forming cytoskeletal - - - 0.0000000000104 74.0
HKD1_k127_7685460_0 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 492.0
HKD1_k127_7685460_1 Glucose inhibited division protein A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001205 255.0
HKD1_k127_7685460_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000002145 177.0
HKD1_k127_7685460_3 - - - - 0.000000000000000000000000005653 121.0
HKD1_k127_7694705_0 Enoyl-CoA hydratase/isomerase K20765 - 3.7.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006073 457.0
HKD1_k127_7694705_1 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 385.0
HKD1_k127_7694705_2 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000003713 201.0
HKD1_k127_7694705_3 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000006888 169.0
HKD1_k127_7697451_0 elongation factor G domain IV K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 608.0
HKD1_k127_7697451_1 Rieske 2Fe-2S - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 400.0
HKD1_k127_7697451_10 PFAM ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000007154 141.0
HKD1_k127_7697451_11 Diguanylate cyclase - - - 0.00000000001157 79.0
HKD1_k127_7697451_12 histidine kinase, dimerisation and phosphoacceptor region - - - 0.000000002858 71.0
HKD1_k127_7697451_13 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit - - - 0.0003512 47.0
HKD1_k127_7697451_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 317.0
HKD1_k127_7697451_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K02405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003268 252.0
HKD1_k127_7697451_4 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000002018 266.0
HKD1_k127_7697451_5 - - - - 0.0000000000000000000000000000000000000000000000000006255 206.0
HKD1_k127_7697451_6 Protein phosphatase 2C K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000009623 195.0
HKD1_k127_7697451_7 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000002201 191.0
HKD1_k127_7697451_8 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000005351 186.0
HKD1_k127_7697451_9 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000003571 166.0
HKD1_k127_7700405_0 Oxygenase, catalysing oxidative methylation of damaged DNA K09990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 326.0
HKD1_k127_7700405_1 acyl-CoA thioesterase K10805 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016042,GO:0016054,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042802,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072329,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 314.0
HKD1_k127_7700405_2 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000001788 248.0
HKD1_k127_7700405_3 6-O-methylguanine DNA methyltransferase, DNA binding domain - - - 0.000000000000000000000000000000000000000000000000000001255 201.0
HKD1_k127_7700405_4 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749,K18313 - 2.8.3.16,2.8.3.20 0.00000000000000000000000000000000000000000000000147 179.0
HKD1_k127_7700405_5 Sigma-70, region 4 - - - 0.00000000000002488 74.0
HKD1_k127_7733294_0 Hydantoinase B/oxoprolinase K01469 - 3.5.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 527.0
HKD1_k127_7733294_1 Lysine-2,3-aminomutase K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 528.0
HKD1_k127_7733294_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 328.0
HKD1_k127_7733294_3 PFAM VanZ - - - 0.00000000004007 71.0
HKD1_k127_7733294_4 PFAM AMP-dependent synthetase and ligase - - - 0.000392 44.0
HKD1_k127_773979_0 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 429.0
HKD1_k127_773979_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001569 280.0
HKD1_k127_773979_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004587 291.0
HKD1_k127_773979_3 Arylsulfatase a K01133 - 3.1.6.6 0.0000000000000000000000000000000000000000000000000000000000000005144 236.0
HKD1_k127_773979_4 isochorismatase - - - 0.00000000000000000000000000000000000000000000000000000000002528 226.0
HKD1_k127_773979_5 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.00000000000000000000000000000000000000000001494 179.0
HKD1_k127_773979_6 Hemimethylated DNA-binding protein YccV like K11940 - - 0.000002113 57.0
HKD1_k127_7764936_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 371.0
HKD1_k127_7764936_1 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003154 262.0
HKD1_k127_7764936_2 transcriptional regulator - - - 0.0000000000000000000000000000000007747 142.0
HKD1_k127_7764936_3 PFAM RNA recognition motif - - - 0.0000000000000000000000000000411 122.0
HKD1_k127_7764936_4 - - - - 0.00000000000000000000003776 103.0
HKD1_k127_7779929_0 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004499 392.0
HKD1_k127_7779929_1 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002188 286.0
HKD1_k127_7779929_2 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides - - - 0.000000000000000000000000000000000000000000000006555 190.0
HKD1_k127_7779929_3 ApaG domain K06195 - - 0.00000000000000000000000000000000000003454 159.0
HKD1_k127_7779929_4 nitroreductase - - - 0.0000007783 59.0
HKD1_k127_7790413_0 Flavin-binding monooxygenase-like K03379 - 1.14.13.22 1.509e-226 715.0
HKD1_k127_7790413_1 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 541.0
HKD1_k127_7790413_2 oxidoreductases (related to aryl-alcohol dehydrogenases) - GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016491,GO:0016614,GO:0016616,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034198,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0071496,GO:1990928 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 424.0
HKD1_k127_7790413_3 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000001868 228.0
HKD1_k127_7790413_4 DinB family - - - 0.00000000000000000000000000000000000000000000000000000009369 207.0
HKD1_k127_7790413_5 Methyltransferase - - - 0.00000000000000000000000000000000000000000000003205 181.0
HKD1_k127_7790413_6 alpha beta - - - 0.00000000000000000000000000000000001318 145.0
HKD1_k127_7790413_8 Periplasmic component of the Tol biopolymer transport system - - - 0.0003775 52.0
HKD1_k127_780307_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 6.649e-227 721.0
HKD1_k127_780307_1 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 567.0
HKD1_k127_780307_2 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000514 357.0
HKD1_k127_780307_3 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000001497 265.0
HKD1_k127_780307_4 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000001244 190.0
HKD1_k127_780307_5 Phage Tail Collar - - - 0.00000000000000000000000000000000000000000000001338 175.0
HKD1_k127_780307_6 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000006449 154.0
HKD1_k127_7824976_0 DNA polymerase type-B family K02336 - 2.7.7.7 7.427e-195 640.0
HKD1_k127_7850867_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 384.0
HKD1_k127_7850867_1 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 305.0
HKD1_k127_7850867_2 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006848 271.0
HKD1_k127_7850867_3 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000005878 228.0
HKD1_k127_7850867_4 Domain of unknown function (DUF427) - - - 0.000000000000000000000000000000001697 138.0
HKD1_k127_7850867_5 PFAM Endonuclease Exonuclease phosphatase - - - 0.000000000003025 80.0
HKD1_k127_7850867_6 Ankyrin repeat K06867 - - 0.0000000000162 69.0
HKD1_k127_7850867_7 Sulfotransferase family - - - 0.00000000001941 75.0
HKD1_k127_7850867_8 sphingolipid transporter activity - - - 0.000000000666 66.0
HKD1_k127_7861543_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 2.504e-289 927.0
HKD1_k127_7861543_1 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000005218 253.0
HKD1_k127_7861543_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000008806 169.0
HKD1_k127_7861543_3 peptidyl-tyrosine sulfation - - - 0.000000000001256 79.0
HKD1_k127_7883722_0 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 414.0
HKD1_k127_7883722_1 Cytochrome P450 - - - 0.00000000000000000001636 101.0
HKD1_k127_7885271_0 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003024 270.0
HKD1_k127_7885271_1 Sterol carrier protein domain - - - 0.00000000000000000000000000000000000000000000000000001444 213.0
HKD1_k127_7885271_2 PHP domain protein - - - 0.000000000000000000000000000000000000000000000000002421 206.0
HKD1_k127_7885271_3 - - - - 0.0000000000000000000000003201 110.0
HKD1_k127_7885271_4 membrane protein (homolog of Drosophila rhomboid) - - - 0.00000000000001842 87.0
HKD1_k127_7885271_5 - - - - 0.0000000000009995 80.0
HKD1_k127_7885271_6 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.00000000002543 76.0
HKD1_k127_7920477_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004789 563.0
HKD1_k127_7920477_1 AIR synthase related protein, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003478 471.0
HKD1_k127_7920477_2 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006991 292.0
HKD1_k127_7920477_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003334 286.0
HKD1_k127_7920477_4 DoxX K15977 - - 0.000000000000000000000000000000000000000000000000005218 183.0
HKD1_k127_7932784_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005766 458.0
HKD1_k127_7932784_1 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 327.0
HKD1_k127_7932784_2 Histidine kinase K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000006844 216.0
HKD1_k127_7932784_3 Histidine kinase - - - 0.00000000000000000000004688 100.0
HKD1_k127_7932784_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.00000002507 64.0
HKD1_k127_7947794_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 4.853e-224 700.0
HKD1_k127_7947794_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 342.0
HKD1_k127_7947794_10 R3H domain protein K06346 - - 0.00000000000006534 82.0
HKD1_k127_7947794_11 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000009367 76.0
HKD1_k127_7947794_12 Polymer-forming cytoskeletal - - - 0.00000000001209 76.0
HKD1_k127_7947794_13 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000001453 70.0
HKD1_k127_7947794_14 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000642 49.0
HKD1_k127_7947794_2 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 297.0
HKD1_k127_7947794_3 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004446 280.0
HKD1_k127_7947794_4 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000001427 238.0
HKD1_k127_7947794_5 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000004234 223.0
HKD1_k127_7947794_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000008681 133.0
HKD1_k127_7947794_7 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000002289 102.0
HKD1_k127_7947794_8 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000002435 105.0
HKD1_k127_7947794_9 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.00000000000000000004617 98.0
HKD1_k127_7963334_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 328.0
HKD1_k127_7963334_1 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005005 299.0
HKD1_k127_7963334_2 Acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001966 277.0
HKD1_k127_7963334_3 protein methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003979 269.0
HKD1_k127_7963334_4 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000005896 287.0
HKD1_k127_7963334_5 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000006081 182.0
HKD1_k127_7963334_6 tRNA nucleotidyltransferase poly(A) polymerase K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000008096 165.0
HKD1_k127_7963334_7 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000001743 130.0
HKD1_k127_7963334_8 glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.00000002731 64.0
HKD1_k127_7963334_9 glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.000001181 59.0
HKD1_k127_7966022_0 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 355.0
HKD1_k127_7966022_1 histidine kinase HAMP region domain protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000001034 227.0
HKD1_k127_7966022_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000002364 158.0
HKD1_k127_7966022_3 PFAM response regulator receiver K03413 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000003966 144.0
HKD1_k127_7966022_4 CheC inhibitor of MCP methylation K03410 - - 0.00000056 63.0
HKD1_k127_7966935_0 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000000000005781 208.0
HKD1_k127_7966935_1 - - - - 0.0000000000000000000000003022 112.0
HKD1_k127_7968362_0 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001515 287.0
HKD1_k127_7968362_1 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000245 209.0
HKD1_k127_7968362_2 Glycine-zipper domain - - - 0.00000000000000008775 96.0
HKD1_k127_7975114_0 ABC transporter K02471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005986 594.0
HKD1_k127_7975114_1 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 586.0
HKD1_k127_7975114_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000001625 251.0
HKD1_k127_7975114_3 - - - - 0.00000000000000000000000000000000000001586 151.0
HKD1_k127_7975114_4 - - - - 0.000000000000000000000001477 107.0
HKD1_k127_7975114_6 Required for optimal acid stress protection. Exhibits a chaperone-like activity only at low pH by suppressing non- specifically the aggregation of denaturated periplasmic proteins K19777 GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0042802,GO:0050896,GO:0051087,GO:0051716,GO:0071214,GO:0071467,GO:0071468,GO:0104004 - 0.00001164 54.0
HKD1_k127_7995383_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 538.0
HKD1_k127_7995383_1 Glucose dehydrogenase C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 424.0
HKD1_k127_7995383_10 - - - - 0.00000000000001273 76.0
HKD1_k127_7995383_11 BON domain - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0032153,GO:0044462,GO:0044464,GO:0071944 - 0.000000002288 69.0
HKD1_k127_7995383_12 bacterial OsmY and nodulation domain - - - 0.00003012 50.0
HKD1_k127_7995383_13 bacterial OsmY and nodulation domain K04065 - - 0.00006167 55.0
HKD1_k127_7995383_2 cytochrome P450 K15981 - 1.14.13.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 375.0
HKD1_k127_7995383_3 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 355.0
HKD1_k127_7995383_4 MazG family K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000001253 232.0
HKD1_k127_7995383_5 Domain of unknown function (DUF814) - - - 0.0000000000000000000000000000000000000000000000000000000000001344 233.0
HKD1_k127_7995383_6 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000002892 220.0
HKD1_k127_7995383_7 metal-dependent phosphohydrolase, HD sub domain - - - 0.0000000000000000000000000000000004209 147.0
HKD1_k127_7995383_8 belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.000000000000000000000000000643 119.0
HKD1_k127_7995383_9 transcriptional regulator K09017 - - 0.0000000000000000000000433 107.0
HKD1_k127_8012040_0 Aminotransferase class I and II K00652 - 2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000564 462.0
HKD1_k127_8012040_1 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935,K02169 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197,6.3.3.3 0.00000000000000000000000000000000000000000000000004636 199.0
HKD1_k127_8012040_2 Aminotransferase class-III K00833 - 2.6.1.62 0.00000000000000000000000000002986 125.0
HKD1_k127_8012040_3 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 0.000006013 48.0
HKD1_k127_819272_0 PAS PAC sensor signal transduction histidine kinase K19661 - 2.7.13.3 0.0000000000000000000000000000000000009241 159.0
HKD1_k127_832893_0 Mur ligase family, catalytic domain K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 451.0
HKD1_k127_832893_1 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 314.0
HKD1_k127_832893_2 Replicative DNA helicase K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 310.0
HKD1_k127_832893_3 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003466 287.0
HKD1_k127_832893_4 LD-carboxypeptidase K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000005952 222.0
HKD1_k127_832893_5 AMMECR1 K09141 - - 0.0000000000000000000000000000000000000000003223 168.0
HKD1_k127_832893_6 Pyruvate formate lyase-activating protein K04069 - 1.97.1.4 0.000000000000000000000000000009365 118.0
HKD1_k127_839969_0 synthetase K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 608.0
HKD1_k127_839969_1 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 287.0
HKD1_k127_839969_2 F420H(2)-dependent quinone reductase - - - 0.0000000000000000000000006832 105.0
HKD1_k127_855955_0 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 544.0
HKD1_k127_855955_1 Belongs to the TPP enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 528.0
HKD1_k127_855955_2 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 422.0
HKD1_k127_855955_3 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 370.0
HKD1_k127_855955_4 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000003453 248.0
HKD1_k127_855955_5 Belongs to the Dps family K04047 - - 0.0000000000000000000000000000000000000000000000000000889 192.0
HKD1_k127_855955_6 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000001905 171.0
HKD1_k127_855955_7 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000003396 142.0
HKD1_k127_855955_8 PFAM OmpA MotB domain protein K03640 - - 0.0000000000000000000000000004131 121.0
HKD1_k127_855955_9 EXOIII K02342 - 2.7.7.7 0.0000000000000000001659 96.0
HKD1_k127_870534_0 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 383.0
HKD1_k127_870534_1 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009721 304.0
HKD1_k127_873178_0 - - - - 0.00000000000000000000001131 117.0
HKD1_k127_881955_0 UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 315.0
HKD1_k127_881955_1 ThiF family K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000003276 148.0
HKD1_k127_881955_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000006215 136.0
HKD1_k127_881955_3 SMART Tetratricopeptide domain protein - - - 0.000000000000003515 89.0
HKD1_k127_98166_0 AAA ATPase domain - - - 0.000000000000000000000000003431 130.0